Mus musculus

0 known processes

Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

(Aliases: D130059B05Rik,BIG1,ARFGEP1,P200,D730028O18Rik)

Arfgef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide metabolic processGO:00091173320.108
Human
small gtpase mediated signal transductionGO:0007264970.083
purine containing compound metabolic processGO:00725213110.083
Human
cation transportGO:00068123990.082
purine nucleoside triphosphate catabolic processGO:00091462030.075
Human
nucleoside triphosphate catabolic processGO:00091432050.075
Human
endomembrane system organizationGO:00102561470.074
Human
organic cyclic compound catabolic processGO:19013612950.074
Human
gtp metabolic processGO:00460391440.070
Human
positive regulation of protein modification processGO:00314012990.069
Human
nucleoside phosphate metabolic processGO:00067533380.069
Human
cellular nitrogen compound catabolic processGO:00442702800.067
Human
purine nucleoside metabolic processGO:00422782410.067
Human
positive regulation of protein phosphorylationGO:00019342420.065
organelle localizationGO:00516401790.064
nucleoside metabolic processGO:00091162460.063
Human
modification dependent protein catabolic processGO:00199411330.063
positive regulation of cellular catabolic processGO:00313311480.061
Human
synaptic transmissionGO:00072683290.060
regulation of ion transportGO:00432692150.060
cation homeostasisGO:00550802120.059
purine ribonucleotide metabolic processGO:00091502900.059
Human
purine nucleoside triphosphate metabolic processGO:00091442260.059
Human
ribonucleoside triphosphate metabolic processGO:00091992200.055
Human
macromolecule catabolic processGO:00090572810.054
heterocycle catabolic processGO:00467002800.053
Human
cell type specific apoptotic processGO:00972852680.051
protein modification by small protein removalGO:0070646210.050
negative regulation of protein metabolic processGO:00512482820.050
protein deubiquitinationGO:0016579190.050
guanosine containing compound metabolic processGO:19010681440.050
Human
intracellular protein transportGO:00068862040.050
posttranscriptional regulation of gene expressionGO:00106081550.049
membrane organizationGO:00610242450.049
purine ribonucleoside triphosphate catabolic processGO:00092071990.049
Human
regulation of cellular component sizeGO:00325351210.049
Human
nucleoside phosphate catabolic processGO:19012922220.048
Human
glycosyl compound metabolic processGO:19016572460.047
Human
cellular protein catabolic processGO:00442571550.046
ras protein signal transductionGO:0007265770.045
lipid localizationGO:00108761260.045
divalent metal ion transportGO:00708381720.045
purine containing compound catabolic processGO:00725232130.043
Human
regulation of ion transmembrane transportGO:00347651190.043
establishment of organelle localizationGO:00516561220.043
positive regulation of protein kinase activityGO:00458601440.042
positive regulation of cellular amine metabolic processGO:003324050.042
purine ribonucleotide catabolic processGO:00091542080.042
Human
regulation of purine nucleotide catabolic processGO:00331211220.041
Human
purine nucleotide catabolic processGO:00061952110.041
Human
microtubule cytoskeleton organizationGO:00002261570.040
divalent inorganic cation transportGO:00725111780.040
purine ribonucleoside catabolic processGO:00461302050.040
Human
organonitrogen compound catabolic processGO:19015652640.040
Human
nucleoside triphosphate metabolic processGO:00091412300.040
Human
regulation of neuron deathGO:19012141340.039
protein modification by small protein conjugationGO:00324461870.039
regulation of vesicle mediated transportGO:00606271390.039
negative regulation of neuron deathGO:1901215980.039
regulation of cell motilityGO:20001452360.038
regulation of cellular catabolic processGO:00313292420.038
Human
regulation of protein kinase activityGO:00458592320.038
cytoplasmic transportGO:00164822340.038
negative regulation of molecular functionGO:00440922580.037
Human
regulation of nucleoside metabolic processGO:00091181300.036
Human
regulation of transmembrane transportGO:00347621280.036
synaptic vesicle localizationGO:0097479590.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.036
Human
purine nucleotide metabolic processGO:00061633020.036
Human
protein targetingGO:00066051430.035
ion transmembrane transportGO:00342203610.035
guanosine containing compound catabolic processGO:19010691440.035
Human
cellular ketone metabolic processGO:0042180840.035
regulation of cellular ketone metabolic processGO:0010565660.035
calcium ion homeostasisGO:00550741270.035
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
cellular homeostasisGO:00197252400.035
cellular amino acid metabolic processGO:00065201030.035
cellular response to dna damage stimulusGO:00069742070.034
cellular chemical homeostasisGO:00550822150.034
establishment of vesicle localizationGO:0051650810.034
apical constrictionGO:000338340.034
regulation of cell migrationGO:00303342190.034
calcium ion transportGO:00068161590.033
metal ion homeostasisGO:00550651890.033
synapse organizationGO:00508081250.033
ribonucleotide metabolic processGO:00092592910.032
Human
regulation of nucleotide catabolic processGO:00308111220.032
Human
cell adhesionGO:00071553290.032
rho protein signal transductionGO:0007266320.032
centrosome cycleGO:0007098230.032
endocytosisGO:00068971680.032
regulation of metal ion transportGO:00109591060.031
gland developmentGO:00487323300.031
positive regulation of ras gtpase activityGO:0032320650.031
cell substrate adhesionGO:00315891300.031
cell junction organizationGO:0034330770.031
amine metabolic processGO:0009308450.030
glycosyl compound catabolic processGO:19016582060.030
Human
purine nucleoside catabolic processGO:00061522050.030
Human
cellular ion homeostasisGO:00068731650.030
regulation of neuron apoptotic processGO:00435231220.030
regulation of transferase activityGO:00513382630.030
protein localization to nucleusGO:00345041210.030
regulation of neuron differentiationGO:00456642810.030
protein modification by small protein conjugation or removalGO:00706472070.030
organophosphate catabolic processGO:00464342320.030
Human
neuron apoptotic processGO:00514021420.030
ribose phosphate metabolic processGO:00196932910.030
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.029
ribonucleotide catabolic processGO:00092612080.029
Human
regulation of nucleotide metabolic processGO:00061401690.029
Human
regulation of cell projection organizationGO:00313442060.029
maintenance of locationGO:0051235890.029
ameboidal type cell migrationGO:00016671280.028
regulation of organelle organizationGO:00330432890.028
Human
gtp catabolic processGO:00061841430.028
Human
response to transforming growth factor betaGO:0071559880.028
positive regulation of kinase activityGO:00336741550.028
dna repairGO:00062811070.028
regulation of hydrolase activityGO:00513362460.027
Human
cellular amine metabolic processGO:0044106440.027
mapk cascadeGO:00001652810.027
negative regulation of phosphorylationGO:00423261660.027
ribonucleoside metabolic processGO:00091192450.027
Human
microtubule based processGO:00070172360.026
aromatic compound catabolic processGO:00194392860.026
Human
nucleotide catabolic processGO:00091662170.026
Human
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.026
transmembrane transportGO:00550854120.026
nucleoside catabolic processGO:00091642060.026
Human
positive regulation of nucleoside metabolic processGO:0045979910.026
Human
response to osmotic stressGO:0006970210.026
homeostasis of number of cellsGO:00488722100.026
response to growth factorGO:00708481980.026
neuron deathGO:00709971540.026
regulation of cellular amine metabolic processGO:0033238200.026
establishment of synaptic vesicle localizationGO:0097480570.025
apoptotic signaling pathwayGO:00971903060.025
regulation of protein localizationGO:00328802310.025
blood vessel morphogenesisGO:00485142850.025
morphogenesis of embryonic epitheliumGO:00163311590.025
carbohydrate derivative catabolic processGO:19011362310.024
Human
mesodermal cell migrationGO:000807840.024
regulation of kinase activityGO:00435492490.024
regulation of cytoskeleton organizationGO:00514931220.024
Human
negative regulation of intracellular signal transductionGO:19025321670.024
regulation of endocytosisGO:0030100690.024
sequestering of calcium ionGO:0051208180.024
plasma membrane organizationGO:0007009900.024
lipid homeostasisGO:0055088630.023
cellular response to growth factor stimulusGO:00713631970.023
regulation of cellular amino acid metabolic processGO:000652150.023
actin filament polymerizationGO:0030041440.023
Human
tube formationGO:00351481400.023
neural tube developmentGO:00219151600.023
vesicle coatingGO:000690120.023
regulation of cellular response to stressGO:00801351590.023
intermediate filament based processGO:0045103270.023
positive regulation of hydrolase activityGO:00513451480.022
Human
regulation of peptidase activityGO:0052547960.022
response to radiationGO:00093141650.022
stress activated protein kinase signaling cascadeGO:0031098810.022
cellular macromolecule catabolic processGO:00442652060.022
synaptic vesicle transportGO:0048489570.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
sensory organ morphogenesisGO:00905962420.022
protein ubiquitinationGO:00165671710.022
embryonic epithelial tube formationGO:00018381300.022
cell divisionGO:00513011200.021
actin cytoskeleton organizationGO:00300362200.021
Human
inorganic ion transmembrane transportGO:00986602340.021
positive regulation of transferase activityGO:00513471670.021
positive regulation of organelle organizationGO:00106381280.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.021
centrosome duplicationGO:0051298160.021
chemotaxisGO:00069352470.021
locomotory behaviorGO:00076261950.021
exocytosisGO:00068871210.021
stress activated mapk cascadeGO:0051403800.020
positive regulation of ion transportGO:0043270650.020
cell junction assemblyGO:0034329520.020
negative regulation of immune system processGO:00026832090.020
amide transportGO:00428861380.020
transforming growth factor beta receptor signaling pathwayGO:0007179710.020
neural tube formationGO:00018411080.020
dendrite developmentGO:00163581150.020
cytokine productionGO:00018163190.020
response to oxidative stressGO:00069791230.019
negative regulation of phosphate metabolic processGO:00459361840.019
Human
intermediate filament cytoskeleton organizationGO:0045104260.019
peptide transportGO:00158331330.019
regulation of cellular component biogenesisGO:00440871810.019
Human
ribonucleoside catabolic processGO:00424542060.019
Human
muscle system processGO:00030121410.019
covalent chromatin modificationGO:00165691630.019
divalent inorganic cation homeostasisGO:00725071380.018
regulation of cell shapeGO:0008360390.018
golgi to endosome transportGO:000689530.018
lipid biosynthetic processGO:00086101790.018
cellular response to transforming growth factor beta stimulusGO:0071560880.018
response to uvGO:0009411440.018
regulation of calcium ion transportGO:0051924690.018
regulation of proteolysisGO:00301621640.018
cellular metal ion homeostasisGO:00068751510.018
positive regulation of gtpase activityGO:0043547850.018
Human
regulation of apoptotic signaling pathwayGO:20012331970.018
establishment of protein localization to organelleGO:00725941180.018
vesicle localizationGO:0051648860.018
response to peptideGO:19016521360.018
response to organic cyclic compoundGO:00140701980.018
ribonucleoside triphosphate catabolic processGO:00092031990.017
Human
lipid transportGO:0006869980.017
regulation of mapk cascadeGO:00434082480.017
granulocyte migrationGO:0097530430.017
peptidyl amino acid modificationGO:00181933360.017
protein polymerizationGO:0051258570.017
Human
mitotic cytokinesisGO:000028140.017
phosphatidylethanolamine metabolic processGO:004633720.017
epithelial cell developmentGO:00020641590.017
nitrogen compound transportGO:00717052710.017
chromatin organizationGO:00063252060.017
regulation of cell substrate adhesionGO:0010810730.017
cellular calcium ion homeostasisGO:00068741190.017
nucleobase containing small molecule metabolic processGO:00550863520.017
Human
negative regulation of cellular response to growth factor stimulusGO:0090288460.017
epithelial tube formationGO:00721751300.017
cell cell junction organizationGO:0045216720.017
protein catabolic processGO:00301632210.017
adult behaviorGO:00305341350.017
compound eye developmentGO:004874910.016
establishment of protein localization to membraneGO:0090150540.016
neural tube closureGO:0001843900.016
inorganic cation transmembrane transportGO:00986622070.016
regulation of lymphocyte activationGO:00512492400.016
regulation of actin filament based processGO:0032970990.015
Human
regulation of anatomical structure sizeGO:00900661780.015
Human
rac protein signal transductionGO:0016601130.015
asymmetric stem cell divisionGO:009872230.015
methylationGO:00322591340.015
ubiquitin dependent protein catabolic processGO:00065111290.015
sequestering of metal ionGO:0051238190.015
regulation of microtubule cytoskeleton organizationGO:0070507370.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
cation transmembrane transportGO:00986552660.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of secretionGO:00510462740.015
regulation of purine nucleotide metabolic processGO:19005421690.015
Human
negative regulation of transferase activityGO:0051348850.015
modification dependent macromolecule catabolic processGO:00436321330.014
regulation of gtp catabolic processGO:00331241130.014
Human
regulation of hormone levelsGO:00108172110.014
epithelium migrationGO:0090132630.014
monoubiquitinated protein deubiquitinationGO:003552020.014
purine ribonucleoside metabolic processGO:00461282410.014
Human
chromatin modificationGO:00165681870.014
regulation of cell activationGO:00508652890.014
jnk cascadeGO:0007254720.014
immune effector processGO:00022523210.014
axonogenesisGO:00074092740.014
mitotic cell cycle processGO:19030471590.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
synapsisGO:0007129340.013
response to organonitrogen compoundGO:00102432460.013
neuronal action potentialGO:0019228540.013
negative regulation of mapk cascadeGO:0043409650.013
actin filament based movementGO:0030048230.013
cellular lipid metabolic processGO:00442553230.013
actin mediated cell contractionGO:0070252150.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
Human
phagocytosisGO:0006909660.013
cellular protein complex assemblyGO:00436231160.013
Human
negative regulation of apoptotic signaling pathwayGO:20012341040.013
peptide secretionGO:00027901140.013
tissue homeostasisGO:00018941150.013
positive regulation of ion transmembrane transportGO:0034767240.013
regulation of endopeptidase activityGO:0052548890.013
neurofilament cytoskeleton organizationGO:0060052100.013
glycerolipid biosynthetic processGO:0045017500.013
lymphocyte proliferationGO:00466511640.013
epithelial tube morphogenesisGO:00605623030.013
protein localization to organelleGO:00333651850.013
macromolecule methylationGO:00434141200.013
protein localization to membraneGO:00726571080.013
transmission of nerve impulseGO:0019226760.013
regulation of intracellular transportGO:00323861590.013
adherens junction organizationGO:0034332280.012
regulation of androgen receptor signaling pathwayGO:006076530.012
angiogenesisGO:00015252010.012
regulation of cell cycle processGO:00105641600.012
carbohydrate metabolic processGO:00059752300.012
Human
mitotic cell cycleGO:00002781950.012
dephosphorylationGO:00163111290.012
positive regulation of transmembrane transportGO:0034764290.012
protein autophosphorylationGO:0046777610.012
organelle fissionGO:00482851700.012
actin filament bundle assemblyGO:0051017400.012
leukocyte differentiationGO:00025213420.012
insulin secretionGO:0030073890.012
cellular response to biotic stimulusGO:0071216920.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
nuclear importGO:0051170950.012
organophosphate biosynthetic processGO:00904071220.012
protein localization to plasma membraneGO:0072659570.012
regulation of ras gtpase activityGO:0032318880.012
Human
calcium mediated signalingGO:0019722460.012
cellular response to peptide hormone stimulusGO:0071375920.012
primary neural tube formationGO:0014020950.012
protein maturationGO:00516041760.012
positive regulation of cytoskeleton organizationGO:0051495490.012
dna metabolic processGO:00062593030.012
positive regulation of actin filament bundle assemblyGO:0032233110.012
positive regulation of protein complex assemblyGO:0031334450.012
carbohydrate derivative biosynthetic processGO:19011371830.012
Human
receptor mediated endocytosisGO:0006898510.012
respiratory system developmentGO:00605411900.012
monocarboxylic acid metabolic processGO:00327871910.012
learning or memoryGO:00076111480.011
regulation of neuron projection developmentGO:00109751690.011
cellular response to organonitrogen compoundGO:00714171450.011
respiratory tube developmentGO:00303231670.011
multicellular organismal homeostasisGO:00488711640.011
negative regulation of cellular protein metabolic processGO:00322692470.011
negative regulation of neuron apoptotic processGO:0043524920.011
positive regulation of cell motilityGO:20001471160.011
negative regulation of phosphorus metabolic processGO:00105631840.011
Human
epidermis developmentGO:00085441870.011
positive regulation of cell adhesionGO:0045785800.011
regulation of angiogenesisGO:0045765810.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
establishment of tissue polarityGO:0007164280.011
actin filament organizationGO:00070151130.011
Human
leukocyte mediated immunityGO:00024431740.011
regulation of rho protein signal transductionGO:0035023710.011
Human
regulation of cell cycleGO:00517262810.011
cognitionGO:00508901490.011
cell activation involved in immune responseGO:00022631260.011
cellular response to radiationGO:0071478280.011
protein polyubiquitinationGO:0000209330.011
cofactor biosynthetic processGO:0051188410.011
intracellular steroid hormone receptor signaling pathwayGO:0030518290.011
organonitrogen compound biosynthetic processGO:19015661920.011
sensory perception of soundGO:0007605970.011
glucose homeostasisGO:00425931280.011
histone modificationGO:00165701590.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
non canonical wnt signaling pathwayGO:0035567330.011
protein import into nucleusGO:0006606950.011
positive regulation of nucleotide catabolic processGO:0030813880.011
Human
response to calcium ionGO:0051592200.011
maintenance of apical basal cell polarityGO:003509030.010
multicellular organismal signalingGO:0035637910.010
centrosome organizationGO:0051297260.010
germ cell developmentGO:00072811850.010
regulation of cytoplasmic transportGO:19036491120.010
negative regulation of protein phosphorylationGO:00019331260.010
regulation of ras protein signal transductionGO:00465781140.010
Human
single organism cell adhesionGO:00986021560.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
protein glycosylationGO:0006486550.010
Human
cofactor metabolic processGO:0051186800.010
positive regulation of proteolysisGO:0045862850.010
rhythmic processGO:00485111740.010
leukocyte migrationGO:00509001240.010
regulation of innate immune responseGO:0045088910.010
bmp signaling pathwayGO:0030509930.010
small molecule biosynthetic processGO:00442831320.010
epithelial cell morphogenesisGO:0003382410.010
cell chemotaxisGO:0060326810.010

Arfgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.049
cancerDOID:16200.049
organ system cancerDOID:005068600.046
musculoskeletal system diseaseDOID:1700.024
disease of anatomical entityDOID:700.024
connective tissue diseaseDOID:6500.018
bone diseaseDOID:008000100.017
bone development diseaseDOID:008000600.014
osteochondrodysplasiaDOID:225600.013
integumentary system diseaseDOID:1600.010