Mus musculus

54 known processes

Sec63

SEC63-like (S. cerevisiae)

(Aliases: AI649014,5730478J10Rik,AW319215)

Sec63 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule catabolic processGO:00442652060.145
organic cyclic compound catabolic processGO:19013612950.090
proteasomal protein catabolic processGO:0010498980.083
regulation of neuron differentiationGO:00456642810.076
transmembrane transportGO:00550854120.076
cell growthGO:00160491300.074
macromolecule catabolic processGO:00090572810.073
cytoplasmic transportGO:00164822340.072
nucleobase containing small molecule metabolic processGO:00550863520.072
aromatic compound catabolic processGO:00194392860.072
membrane organizationGO:00610242450.071
cation homeostasisGO:00550802120.063
gland developmentGO:00487323300.058
ribose phosphate metabolic processGO:00196932910.056
ubiquitin dependent protein catabolic processGO:00065111290.053
organonitrogen compound catabolic processGO:19015652640.052
intra golgi vesicle mediated transportGO:000689110.052
compound eye developmentGO:004874910.052
regulation of cell projection organizationGO:00313442060.050
response to endoplasmic reticulum stressGO:0034976530.050
Zebrafish
regulation of cell motilityGO:20001452360.050
purine ribonucleotide metabolic processGO:00091502900.049
nucleoside catabolic processGO:00091642060.046
maintenance of locationGO:0051235890.046
lipid localizationGO:00108761260.045
glycosyl compound catabolic processGO:19016582060.044
carbohydrate derivative catabolic processGO:19011362310.044
cation transportGO:00068123990.043
protein catabolic processGO:00301632210.043
actin cytoskeleton organizationGO:00300362200.042
ribonucleotide metabolic processGO:00092592910.042
cellular protein catabolic processGO:00442571550.042
nucleotide catabolic processGO:00091662170.041
purine containing compound metabolic processGO:00725213110.040
response to organic cyclic compoundGO:00140701980.038
axonogenesisGO:00074092740.038
ribonucleoside catabolic processGO:00424542060.038
negative regulation of molecular functionGO:00440922580.038
neuron apoptotic processGO:00514021420.038
regulation of intracellular protein transportGO:0033157820.038
posttranscriptional regulation of gene expressionGO:00106081550.037
activation of mapk activity involved in innate immune responseGO:003541920.037
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.036
innate immune responseGO:00450871570.036
proteolysis involved in cellular protein catabolic processGO:00516031470.035
cellular response to growth factor stimulusGO:00713631970.035
lateral inhibitionGO:004633110.035
renal system developmentGO:00720012250.035
purine nucleoside catabolic processGO:00061522050.034
regulation of neuron projection developmentGO:00109751690.034
nucleoside triphosphate catabolic processGO:00091432050.034
response to topologically incorrect proteinGO:0035966250.034
Zebrafish
purine nucleoside triphosphate metabolic processGO:00091442260.033
purine nucleotide catabolic processGO:00061952110.033
response to radiationGO:00093141650.033
inorganic cation transmembrane transportGO:00986622070.033
cellular nitrogen compound catabolic processGO:00442702800.031
endocytosisGO:00068971680.031
vacuole organizationGO:0007033380.031
regulation of secretionGO:00510462740.031
positive regulation of transferase activityGO:00513471670.030
cytokine productionGO:00018163190.030
nucleotide metabolic processGO:00091173320.029
modification dependent protein catabolic processGO:00199411330.029
cation transmembrane transportGO:00986552660.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
purine ribonucleoside metabolic processGO:00461282410.029
purine nucleoside triphosphate catabolic processGO:00091462030.028
negative regulation of protein metabolic processGO:00512482820.028
nucleoside phosphate metabolic processGO:00067533380.028
regulation of hydrolase activityGO:00513362460.028
cellular ketone metabolic processGO:0042180840.028
skeletal system developmentGO:00015013560.028
inorganic ion transmembrane transportGO:00986602340.028
ribonucleoside metabolic processGO:00091192450.028
cellular amino acid metabolic processGO:00065201030.028
metencephalon developmentGO:0022037890.028
digestive tract developmentGO:00485651900.027
camera type eye developmentGO:00430102660.027
developmental growth involved in morphogenesisGO:00605601380.027
cellular response to biotic stimulusGO:0071216920.027
regulation of protein localizationGO:00328802310.027
regulation of cell adhesionGO:00301551540.027
hindbrain developmentGO:00309021280.027
regulation of cytokine productionGO:00018172660.026
transition metal ion transportGO:0000041380.026
posttranslational protein targeting to membraneGO:000662020.026
protein localization to organelleGO:00333651850.026
locomotory behaviorGO:00076261950.026
organelle disassemblyGO:190300820.026
urogenital system developmentGO:00016552610.025
carbohydrate metabolic processGO:00059752300.025
purine nucleotide metabolic processGO:00061633020.025
liver developmentGO:0001889660.024
regulation of kinase activityGO:00435492490.024
positive regulation of apoptotic processGO:00430652170.024
action potentialGO:0001508780.024
Zebrafish
response to extracellular stimulusGO:00099911270.024
regulation of cell migrationGO:00303342190.024
negative regulation of cytokine productionGO:0001818840.024
nucleoside phosphate catabolic processGO:19012922220.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
forebrain developmentGO:00309003020.024
positive regulation of cell motilityGO:20001471160.024
positive regulation of glial cell proliferationGO:006025240.023
metal ion homeostasisGO:00550651890.023
neuron deathGO:00709971540.023
neuronal action potentialGO:0019228540.023
Zebrafish
translationGO:0006412930.023
regulation of organelle organizationGO:00330432890.023
cell substrate adhesionGO:00315891300.023
purine containing compound catabolic processGO:00725232130.023
establishment of vesicle localizationGO:0051650810.022
thymocyte migrationGO:007267920.022
ion transmembrane transportGO:00342203610.022
cerebellum developmentGO:0021549770.022
ribonucleotide catabolic processGO:00092612080.022
er nucleus signaling pathwayGO:0006984270.022
Zebrafish
positive regulation of hydrolase activityGO:00513451480.022
kidney developmentGO:00018222130.022
regionalizationGO:00030023370.022
regulation of mapk cascadeGO:00434082480.022
regulation of establishment of protein localizationGO:00702011810.021
epithelial tube formationGO:00721751300.021
endoplasmic reticulum unfolded protein responseGO:0030968190.021
Zebrafish
cerebellar cortex developmentGO:0021695480.021
midgut developmentGO:000749440.021
negative regulation of nervous system developmentGO:00519611560.020
organophosphate catabolic processGO:00464342320.020
regulation of cellular catabolic processGO:00313292420.020
inflammatory responseGO:00069542440.020
positive regulation of nervous system developmentGO:00519622210.020
lipid transportGO:0006869980.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
modification dependent macromolecule catabolic processGO:00436321330.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.020
purine nucleoside metabolic processGO:00422782410.020
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
positive regulation of cell migrationGO:00303351090.019
cellular metal ion homeostasisGO:00068751510.019
regulation of protein kinase activityGO:00458592320.019
response to transforming growth factor betaGO:0071559880.019
circulatory system processGO:00030131970.019
response to unfolded proteinGO:0006986210.019
Zebrafish
regulation of thymocyte migrationGO:200041020.019
connective tissue developmentGO:00614481790.019
negative regulation of growthGO:0045926990.019
positive regulation of growthGO:00459271040.019
cellular response to lipidGO:00713961450.019
regulation of membrane potentialGO:00423911920.018
Zebrafish
regulation of transferase activityGO:00513382630.018
positive regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030910.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
purine ribonucleoside catabolic processGO:00461302050.018
cellular ion homeostasisGO:00068731650.018
striated muscle tissue developmentGO:00147062930.018
negative regulation of phosphorus metabolic processGO:00105631840.018
developmental maturationGO:00217001930.018
regulation of proteolysisGO:00301621640.018
anion transportGO:00068201770.018
negative regulation of cellular protein metabolic processGO:00322692470.018
regulation of cell growthGO:0001558910.018
positive regulation of cell growthGO:0030307330.018
cellular protein complex assemblyGO:00436231160.018
muscle cell differentiationGO:00426922610.018
lipid biosynthetic processGO:00086101790.017
ribonucleoprotein complex disassemblyGO:003298830.017
protein oligomerizationGO:0051259670.017
adult locomotory behaviorGO:0008344910.017
ensheathment of neuronsGO:0007272760.017
Zebrafish
regulation of eosinophil migrationGO:200041620.017
muscle tissue developmentGO:00605373080.017
cellular homeostasisGO:00197252400.017
skin developmentGO:00435882200.017
cellular amine metabolic processGO:0044106440.017
cell type specific apoptotic processGO:00972852680.017
mapk cascadeGO:00001652810.017
regulation of hormone levelsGO:00108172110.017
epidermis developmentGO:00085441870.017
male gamete generationGO:00482322850.017
purine ribonucleotide catabolic processGO:00091542080.017
glycoprotein metabolic processGO:00091001160.016
regulation of defense responseGO:00313472330.016
golgi vesicle transportGO:0048193300.016
apoptotic signaling pathwayGO:00971903060.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
gliogenesisGO:00420631410.016
fibronectin dependent thymocyte migrationGO:007268110.016
cell divisionGO:00513011200.016
positive regulation of cell deathGO:00109422240.016
positive regulation of programmed cell deathGO:00430682180.016
adult behaviorGO:00305341350.016
regulation of ion transportGO:00432692150.016
cellular component assembly involved in morphogenesisGO:00109271390.016
morphogenesis of a branching epitheliumGO:00611381930.016
negative regulation of cellular component organizationGO:00511291940.016
regulation of actin filament based processGO:0032970990.016
mrna metabolic processGO:0016071840.016
heterocycle catabolic processGO:00467002800.016
regulation of protein transportGO:00512231630.016
rna interferenceGO:001624620.016
regulation of cellular response to stressGO:00801351590.016
guanosine containing compound metabolic processGO:19010681440.016
blood vessel morphogenesisGO:00485142850.016
regulation of intracellular transportGO:00323861590.015
transmission of nerve impulseGO:0019226760.015
Zebrafish
retina morphogenesis in camera type eyeGO:0060042450.015
positive regulation of cell activationGO:00508671580.015
cellular response to dna damage stimulusGO:00069742070.015
establishment of protein localization to membraneGO:0090150540.015
bmp signaling pathwayGO:0030509930.015
nucleoside triphosphate metabolic processGO:00091412300.015
retina development in camera type eyeGO:00600411190.015
cartilage developmentGO:00512161400.015
positive regulation of thymocyte migrationGO:200041220.015
gtp catabolic processGO:00061841430.015
extracellular structure organizationGO:00430621480.014
immune effector processGO:00022523210.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
myelinationGO:0042552740.014
Zebrafish
positive regulation of eosinophil migrationGO:200041820.014
bone developmentGO:00603481200.014
regulation of cellular ketone metabolic processGO:0010565660.014
lung developmentGO:00303241640.014
organic hydroxy compound metabolic processGO:19016152030.014
regulation of neuron deathGO:19012141340.014
regulation of ossificationGO:00302781120.014
fertilizationGO:00095661270.014
ear developmentGO:00435832000.014
neural tube formationGO:00018411080.014
regulation of cellular component sizeGO:00325351210.014
regulation of bmp signaling pathwayGO:0030510600.014
response to growth factorGO:00708481980.014
phagocytosisGO:0006909660.014
activation of adenylate cyclase activityGO:000719040.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
axon ensheathmentGO:0008366760.014
Zebrafish
cellular chemical homeostasisGO:00550822150.013
prevention of polyspermyGO:006046840.013
regulation of anatomical structure sizeGO:00900661780.013
angiogenesisGO:00015252010.013
regulation of protein localization to nucleusGO:1900180600.013
transforming growth factor beta receptor signaling pathwayGO:0007179710.013
nephron developmentGO:00720061090.013
response to organonitrogen compoundGO:00102432460.013
nucleoside metabolic processGO:00091162460.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
endomembrane system organizationGO:00102561470.013
positive regulation of cell developmentGO:00107202370.013
schwann cell differentiationGO:0014037260.013
stress activated mapk cascadeGO:0051403800.013
heart morphogenesisGO:00030071780.013
regulation of cellular amine metabolic processGO:0033238200.013
regulation of neuron apoptotic processGO:00435231220.013
fat cell differentiationGO:00454441600.013
multicellular organismal signalingGO:0035637910.013
Zebrafish
guanosine containing compound catabolic processGO:19010691440.013
immune response regulating signaling pathwayGO:00027641250.013
amine metabolic processGO:0009308450.013
establishment of endothelial blood brain barrierGO:001404530.013
protein importGO:00170381010.013
positive regulation of neuron differentiationGO:00456661410.013
carbohydrate derivative biosynthetic processGO:19011371830.013
cellular lipid metabolic processGO:00442553230.013
establishment of protein localization to organelleGO:00725941180.013
epithelial tube morphogenesisGO:00605623030.013
positive regulation of secretionGO:00510471300.013
embryonic digit morphogenesisGO:0042733560.012
response to nutrient levelsGO:00316671090.012
regulation of secretion by cellGO:19035302490.012
skeletal system morphogenesisGO:00487052030.012
regulation of metal ion transportGO:00109591060.012
regulation of vesicle mediated transportGO:00606271390.012
positive regulation of protein kinase activityGO:00458601440.012
regulation of gtp catabolic processGO:00331241130.012
morphogenesis of embryonic epitheliumGO:00163311590.012
male anatomical structure morphogenesisGO:009059840.012
male sex differentiationGO:00466611090.012
positive regulation of cytokine productionGO:00018191740.012
actin filament organizationGO:00070151130.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
p38mapk cascadeGO:003806640.012
retrograde vesicle mediated transport golgi to erGO:000689010.012
ameboidal type cell migrationGO:00016671280.012
hormone secretionGO:00468791280.012
regulation of multi organism processGO:00439001110.012
protein modification by small protein conjugationGO:00324461870.012
nucleoside monophosphate metabolic processGO:0009123850.012
developmental cell growthGO:0048588840.012
regulation of apoptotic signaling pathwayGO:20012331970.012
positive regulation of protein phosphorylationGO:00019342420.012
germinal center formationGO:0002467160.012
leukocyte differentiationGO:00025213420.012
calcium ion homeostasisGO:00550741270.012
response to light stimulusGO:00094161350.012
limb morphogenesisGO:00351081490.012
cellular response to external stimulusGO:0071496880.012
zinc ion transportGO:0006829120.012
actin cytoskeleton reorganizationGO:0031532210.012
extracellular matrix organizationGO:00301981470.012
organelle localizationGO:00516401790.011
neural tube developmentGO:00219151600.011
actin modificationGO:003004710.011
eosinophil migrationGO:007267730.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
regulation of purine nucleotide metabolic processGO:19005421690.011
organ growthGO:00352651170.011
divalent inorganic cation transportGO:00725111780.011
determination of left right symmetryGO:0007368800.011
cellular response to radiationGO:0071478280.011
nucleoside monophosphate catabolic processGO:0009125590.011
positive regulation of phospholipase activityGO:001051830.011
glycosyl compound metabolic processGO:19016572460.011
epithelial cell developmentGO:00020641590.011
anatomical structure maturationGO:0071695490.011
regulation of actin cytoskeleton organizationGO:0032956840.011
cell chemotaxisGO:0060326810.011
lymphocyte activation involved in immune responseGO:0002285930.011
embryonic epithelial tube formationGO:00018381300.011
cerebellar purkinje cell layer developmentGO:0021680260.011
fc receptor mediated stimulatory signaling pathwayGO:000243140.011
endodermal digestive tract morphogenesisGO:006103140.011
positive regulation of protein modification processGO:00314012990.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
negative regulation of neuron deathGO:1901215980.011
cellular response to hormone stimulusGO:00328701500.011
mesoderm developmentGO:00074981000.011
regulation of cell activationGO:00508652890.011
stress activated protein kinase signaling cascadeGO:0031098810.011
protein processingGO:00164851630.011
cellular response to transforming growth factor beta stimulusGO:0071560880.011
respiratory system developmentGO:00605411900.011
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.011
dephosphorylationGO:00163111290.011
positive regulation of defense responseGO:00313491240.011
positive regulation of innate immune responseGO:0045089800.011
organophosphate biosynthetic processGO:00904071220.011
rna processingGO:00063961050.011
morphogenesis of a branching structureGO:00017632030.010
regulation of cellular amino acid metabolic processGO:000652150.010
interleukin 8 productionGO:003263740.010
asymmetric stem cell divisionGO:009872230.010
positive regulation of t cell activationGO:00508701010.010
protein targetingGO:00066051430.010
regulation of transmembrane transportGO:00347621280.010
lipid storageGO:0019915360.010
regulation of homeostatic processGO:00328441820.010
regulation of inflammatory responseGO:00507271470.010
single organism cell adhesionGO:00986021560.010
multi multicellular organism processGO:00447061090.010
cellular response to abiotic stimulusGO:0071214560.010
macromolecule methylationGO:00434141200.010
ossificationGO:00015032160.010
methylationGO:00322591340.010
regulation of vacuole organizationGO:004408840.010

Sec63 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.057
eye and adnexa diseaseDOID:149200.057
eye diseaseDOID:561400.057
sensory system diseaseDOID:005015500.057
retinal degenerationDOID:846600.057
disease of anatomical entityDOID:700.057
retinal diseaseDOID:567900.057
disease of metabolismDOID:001466700.032
inherited metabolic disorderDOID:65500.032
disease of cellular proliferationDOID:1456600.018
glomerulosclerosisDOID:005085100.017
urinary system diseaseDOID:1800.017
kidney diseaseDOID:55700.017
glomerulonephritisDOID:292100.017
focal segmental glomerulosclerosisDOID:131200.017
nephritisDOID:1095200.017
intellectual disabilityDOID:105900.016
developmental disorder of mental healthDOID:006003700.016
specific developmental disorderDOID:006003800.016
disease of mental healthDOID:15000.016
non syndromic intellectual disabilityDOID:005088900.016