Mus musculus

0 known processes

Smg1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

(Aliases: 5430435M13Rik,2610207I05Rik,mKIAA0421,C130002K18Rik)

Smg1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.250
heterocycle catabolic processGO:00467002800.174
Human Fly
aromatic compound catabolic processGO:00194392860.165
Human Fly
regulation of organelle organizationGO:00330432890.164
cellular nitrogen compound catabolic processGO:00442702800.158
Human Fly
organonitrogen compound catabolic processGO:19015652640.153
nucleoside phosphate metabolic processGO:00067533380.149
positive regulation of cellular amino acid metabolic processGO:004576430.134
ras protein signal transductionGO:0007265770.134
positive regulation of cellular amine metabolic processGO:003324050.133
purine ribonucleotide catabolic processGO:00091542080.127
small gtpase mediated signal transductionGO:0007264970.125
regulation of cellular amino acid metabolic processGO:000652150.118
purine containing compound metabolic processGO:00725213110.117
purine nucleotide catabolic processGO:00061952110.108
regulation of protein complex assemblyGO:0043254830.105
nucleoside catabolic processGO:00091642060.103
purine ribonucleotide metabolic processGO:00091502900.100
regulation of mapk cascadeGO:00434082480.099
cellular ketone metabolic processGO:0042180840.099
nucleotide metabolic processGO:00091173320.098
regulation of histone methylationGO:0031060300.097
regulation of neuron differentiationGO:00456642810.096
positive regulation of protein modification processGO:00314012990.093
nucleoside triphosphate catabolic processGO:00091432050.088
protein methylationGO:0006479810.088
ribonucleotide catabolic processGO:00092612080.087
ribonucleoside catabolic processGO:00424542060.087
positive regulation of organelle organizationGO:00106381280.086
histone methylationGO:0016571710.086
organophosphate catabolic processGO:00464342320.086
glycosyl compound catabolic processGO:19016582060.084
purine ribonucleoside catabolic processGO:00461302050.083
cellular amino acid metabolic processGO:00065201030.082
covalent chromatin modificationGO:00165691630.081
nucleoside phosphate catabolic processGO:19012922220.080
glycosyl compound metabolic processGO:19016572460.079
rho protein signal transductionGO:0007266320.079
purine nucleoside triphosphate metabolic processGO:00091442260.079
purine ribonucleoside triphosphate catabolic processGO:00092071990.078
nuclear divisionGO:00002801580.077
regulation of cellular catabolic processGO:00313292420.076
purine nucleoside metabolic processGO:00422782410.076
regulation of cell projection organizationGO:00313442060.076
regulation of cellular amine metabolic processGO:0033238200.074
cellular amine metabolic processGO:0044106440.074
protein modification by small protein conjugation or removalGO:00706472070.074
carbohydrate derivative catabolic processGO:19011362310.073
purine nucleoside catabolic processGO:00061522050.072
ribose phosphate metabolic processGO:00196932910.071
methylationGO:00322591340.070
purine ribonucleoside triphosphate metabolic processGO:00092052200.069
axonogenesisGO:00074092740.069
ribonucleoside metabolic processGO:00091192450.069
positive regulation of protein phosphorylationGO:00019342420.068
ribonucleoside triphosphate metabolic processGO:00091992200.067
purine nucleoside triphosphate catabolic processGO:00091462030.067
nucleoside metabolic processGO:00091162460.066
purine nucleotide metabolic processGO:00061633020.063
organic cyclic compound catabolic processGO:19013612950.063
Human Fly
ribonucleotide metabolic processGO:00092592910.062
purine containing compound catabolic processGO:00725232130.061
negative regulation of cellular component organizationGO:00511291940.060
actin cytoskeleton organizationGO:00300362200.058
forebrain developmentGO:00309003020.058
amine metabolic processGO:0009308450.058
regulation of ras protein signal transductionGO:00465781140.057
cellular response to dna damage stimulusGO:00069742070.056
regulation of cellular response to stressGO:00801351590.054
nucleoside triphosphate metabolic processGO:00091412300.054
ribonucleoside triphosphate catabolic processGO:00092031990.053
response to organic cyclic compoundGO:00140701980.052
nucleobase containing small molecule metabolic processGO:00550863520.052
guanosine containing compound metabolic processGO:19010681440.051
cell type specific apoptotic processGO:00972852680.051
regulation of hydrolase activityGO:00513362460.051
regulation of nucleoside metabolic processGO:00091181300.050
negative regulation of phosphorylationGO:00423261660.050
histone h3 k4 trimethylationGO:008018250.049
regulation of purine nucleotide metabolic processGO:19005421690.049
actin filament organizationGO:00070151130.049
histone modificationGO:00165701590.048
regulation of gtp catabolic processGO:00331241130.047
purine ribonucleoside metabolic processGO:00461282410.047
negative regulation of protein metabolic processGO:00512482820.047
regulation of purine nucleotide catabolic processGO:00331211220.046
guanosine containing compound catabolic processGO:19010691440.045
intracellular protein transportGO:00068862040.045
protein alkylationGO:0008213810.045
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.045
positive regulation of cell developmentGO:00107202370.045
histone lysine methylationGO:0034968500.045
synaptic vesicle localizationGO:0097479590.044
Fly
peptidyl lysine methylationGO:0018022290.043
peptidyl amino acid modificationGO:00181933360.043
Human
cellular response to organonitrogen compoundGO:00714171450.043
regulation of cellular component biogenesisGO:00440871810.043
regulation of protein kinase activityGO:00458592320.043
regulation of neuron projection developmentGO:00109751690.042
cell divisionGO:00513011200.042
regulation of nucleotide metabolic processGO:00061401690.041
organelle fissionGO:00482851700.041
mapk cascadeGO:00001652810.040
nucleotide catabolic processGO:00091662170.040
inorganic cation transmembrane transportGO:00986622070.040
regulation of kinase activityGO:00435492490.039
positive regulation of nervous system developmentGO:00519622210.039
peptidyl serine modificationGO:0018209830.038
Human
spermatogenesisGO:00072832840.038
positive regulation of apoptotic processGO:00430652170.037
regulation of cell migrationGO:00303342190.037
chromatin organizationGO:00063252060.036
gtp catabolic processGO:00061841430.036
germ cell developmentGO:00072811850.036
regulation of cytoskeleton organizationGO:00514931220.036
gland developmentGO:00487323300.035
cytoplasmic transportGO:00164822340.035
regulation of nucleotide catabolic processGO:00308111220.034
organic hydroxy compound metabolic processGO:19016152030.034
regulation of cell shapeGO:0008360390.034
microtubule cytoskeleton organizationGO:00002261570.034
regulation of ras gtpase activityGO:0032318880.034
peptidyl threonine phosphorylationGO:0018107310.033
negative regulation of cellular protein metabolic processGO:00322692470.033
regulation of cell motilityGO:20001452360.032
negative regulation of molecular functionGO:00440922580.032
cytokine productionGO:00018163190.032
regulation of cellular component sizeGO:00325351210.032
male gamete generationGO:00482322850.032
posttranscriptional regulation of gene expressionGO:00106081550.031
histone h3 k9 methylationGO:0051567170.031
cellular protein complex assemblyGO:00436231160.031
positive regulation of programmed cell deathGO:00430682180.031
nitrogen compound transportGO:00717052710.030
regulation of cell morphogenesis involved in differentiationGO:00107691510.030
mitotic cell cycleGO:00002781950.030
regulation of apoptotic signaling pathwayGO:20012331970.030
nucleocytoplasmic transportGO:00069131390.029
apoptotic signaling pathwayGO:00971903060.029
macromolecule methylationGO:00434141200.029
actin polymerization or depolymerizationGO:0008154540.029
negative regulation of cell proliferationGO:00082852960.028
establishment of organelle localizationGO:00516561220.028
Fly
positive regulation of kinase activityGO:00336741550.028
chromatin modificationGO:00165681870.028
negative regulation of organelle organizationGO:0010639900.028
response to organonitrogen compoundGO:00102432460.028
positive regulation of cell deathGO:00109422240.027
regulation of actin filament based processGO:0032970990.027
organic hydroxy compound biosynthetic processGO:1901617770.027
regulation of chromatin organizationGO:1902275570.027
regulation of nuclear divisionGO:0051783560.027
peptidyl lysine trimethylationGO:0018023120.026
intracellular receptor signaling pathwayGO:0030522740.026
regulation of cell cycle processGO:00105641600.026
positive regulation of hydrolase activityGO:00513451480.026
positive regulation of mapk cascadeGO:00434101700.026
carbohydrate metabolic processGO:00059752300.026
macromolecule catabolic processGO:00090572810.026
Human Fly
response to peptideGO:19016521360.026
regulation of rho gtpase activityGO:0032319580.025
cellular response to lipidGO:00713961450.025
nuclear transportGO:00511691390.025
compound eye developmentGO:004874910.025
epithelial cell developmentGO:00020641590.025
fertilizationGO:00095661270.024
negative regulation of phosphate metabolic processGO:00459361840.024
muscle system processGO:00030121410.024
organelle localizationGO:00516401790.024
Fly
homeostasis of number of cellsGO:00488722100.024
endomembrane system organizationGO:00102561470.024
cation transportGO:00068123990.024
skeletal system morphogenesisGO:00487052030.024
endocytosisGO:00068971680.023
positive regulation of purine nucleotide metabolic processGO:19005441140.023
regulation of anatomical structure sizeGO:00900661780.023
cellular response to hormone stimulusGO:00328701500.023
regulation of chromosome organizationGO:0033044830.023
actin filament polymerizationGO:0030041440.023
histone h3 k9 trimethylationGO:003612460.023
cellular lipid metabolic processGO:00442553230.023
Human
protein localization to nucleusGO:00345041210.023
membrane organizationGO:00610242450.022
negative regulation of nervous system developmentGO:00519611560.022
central nervous system neuron differentiationGO:00219531620.022
peptidyl tyrosine modificationGO:00182121450.022
gtp metabolic processGO:00460391440.022
divalent inorganic cation transportGO:00725111780.021
myeloid cell differentiationGO:00300992330.021
regulation of wnt signaling pathwayGO:00301111230.021
establishment of vesicle localizationGO:0051650810.021
Fly
adaptive immune responseGO:00022501550.021
cation transmembrane transportGO:00986552660.021
embryonic placenta developmentGO:0001892980.020
protein catabolic processGO:00301632210.020
regulation of cytokine productionGO:00018172660.020
synapse organizationGO:00508081250.020
Fly
response to acid chemicalGO:00011011110.020
regulation of protein localizationGO:00328802310.020
positive regulation of cellular catabolic processGO:00313311480.020
developmental maturationGO:00217001930.020
regulation of intracellular transportGO:00323861590.019
skeletal system developmentGO:00015013560.019
positive regulation of gtpase activityGO:0043547850.019
neuron migrationGO:00017641220.019
negative regulation of cell developmentGO:00107211690.019
rna interferenceGO:001624620.019
regulation of actin filament lengthGO:0030832450.019
regulation of chromatin modificationGO:1903308570.019
regulation of establishment of protein localizationGO:00702011810.019
negative regulation of phosphorus metabolic processGO:00105631840.019
calcium ion transportGO:00068161590.019
dendrite developmentGO:00163581150.019
rhythmic processGO:00485111740.019
blood vessel morphogenesisGO:00485142850.019
cellular response to lipopolysaccharideGO:0071222770.019
protein modification by small protein conjugationGO:00324461870.018
dna metabolic processGO:00062593030.018
small molecule biosynthetic processGO:00442831320.018
chemotaxisGO:00069352470.018
mitotic nuclear divisionGO:0007067480.018
cellular response to insulin stimulusGO:0032869780.018
histone h3 k4 methylationGO:0051568230.018
protein localization to membraneGO:00726571080.018
mitotic cell cycle processGO:19030471590.018
protein polymerizationGO:0051258570.018
peptidyl threonine modificationGO:0018210310.018
primary neural tube formationGO:0014020950.018
cellular homeostasisGO:00197252400.018
mrna processingGO:0006397630.018
morphogenesis of embryonic epitheliumGO:00163311590.018
positive regulation of cell cycleGO:0045787920.018
response to insulinGO:00328681000.018
respiratory tube developmentGO:00303231670.018
developmental growth involved in morphogenesisGO:00605601380.017
multicellular organism growthGO:00352641610.017
regulation of actin polymerization or depolymerizationGO:0008064450.017
regulation of neuron deathGO:19012141340.017
regulation of cell divisionGO:0051302760.017
regulation of transferase activityGO:00513382630.017
positive regulation of nucleotide catabolic processGO:0030813880.016
protein localization to organelleGO:00333651850.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
immune effector processGO:00022523210.016
cellular response to molecule of bacterial originGO:0071219830.016
regulation of rho protein signal transductionGO:0035023710.016
meiotic cell cycleGO:00513211220.016
skin developmentGO:00435882200.016
cellular response to peptide hormone stimulusGO:0071375920.016
peptidyl serine phosphorylationGO:0018105740.016
Human
heart morphogenesisGO:00030071780.016
microtubule based processGO:00070172360.016
regulation of hormone levelsGO:00108172110.016
inorganic ion transmembrane transportGO:00986602340.016
jak stat cascadeGO:0007259420.016
maintenance of locationGO:0051235890.016
sensory system developmentGO:004888030.016
establishment of synaptic vesicle localizationGO:0097480570.016
Fly
positive regulation of nucleotide metabolic processGO:00459811140.016
regulation of organ morphogenesisGO:20000271440.016
cellular response to peptideGO:1901653920.016
epidermis developmentGO:00085441870.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
response to peptide hormoneGO:00434341270.015
regulation of cell adhesionGO:00301551540.015
respiratory system developmentGO:00605411900.015
regulation of histone modificationGO:0031056560.015
response to lipopolysaccharideGO:00324961280.015
wnt signaling pathwayGO:00160551880.015
regulation of mitosisGO:0007088290.015
formation of primary germ layerGO:0001704770.015
carbohydrate derivative biosynthetic processGO:19011371830.015
learning or memoryGO:00076111480.015
transmembrane transportGO:00550854120.014
positive regulation of nucleoside metabolic processGO:0045979910.014
muscle cell differentiationGO:00426922610.014
regulation of cell activationGO:00508652890.014
tissue homeostasisGO:00018941150.014
negative regulation of synapse assemblyGO:005196430.014
synaptic transmissionGO:00072683290.014
Fly
regulation of lymphocyte activationGO:00512492400.014
positive regulation of protein kinase activityGO:00458601440.014
development of primary female sexual characteristicsGO:0046545730.014
regulation of meiotic cell cycleGO:0051445340.014
negative regulation of protein modification processGO:00314001630.014
actin filament bundle assemblyGO:0051017400.014
purine ribonucleoside monophosphate catabolic processGO:0009169570.014
defense response to other organismGO:00985421970.014
positive regulation of lymphocyte activationGO:00512511400.014
wound healingGO:00420601570.014
positive regulation of cytoskeleton organizationGO:0051495490.014
regulation of embryonic developmentGO:0045995710.014
neuromuscular processGO:0050905990.014
cell adhesionGO:00071553290.014
rap protein signal transductionGO:003248630.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
neural tube developmentGO:00219151600.014
positive regulation of erk1 and erk2 cascadeGO:0070374470.014
positive regulation of cell divisionGO:0051781310.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
female gamete generationGO:0007292740.014
positive regulation of cell motilityGO:20001471160.013
positive regulation of mitotic cell cycleGO:0045931410.013
cellular ion homeostasisGO:00068731650.013
stem cell developmentGO:00488642190.013
cellular response to biotic stimulusGO:0071216920.013
ear morphogenesisGO:00424711180.013
regulation of neuron apoptotic processGO:00435231220.013
phagocytosisGO:0006909660.013
vesicle localizationGO:0051648860.013
Fly
response to molecule of bacterial originGO:00022371430.013
peptidyl tyrosine phosphorylationGO:00181081430.013
positive regulation of dna templated transcription elongationGO:003278620.013
regulation of ion transportGO:00432692150.013
divalent metal ion transportGO:00708381720.013
reactive oxygen species metabolic processGO:0072593840.013
hindbrain developmentGO:00309021280.013
regulation of metal ion transportGO:00109591060.013
telencephalon developmentGO:00215371860.013
inner ear morphogenesisGO:00424721010.013
histone h4 k20 methylationGO:003477080.013
peptide transportGO:00158331330.013
biomineral tissue developmentGO:0031214640.013
regulation of cytoplasmic transportGO:19036491120.013
regulation of cell sizeGO:0008361720.013
cell substrate adhesionGO:00315891300.013
negative regulation of hormone metabolic processGO:003235140.013
cellular response to organic cyclic compoundGO:0071407870.013
neuron deathGO:00709971540.013
divalent inorganic cation homeostasisGO:00725071380.013
stem cell maintenanceGO:00198271300.013
cellularizationGO:000734910.013
negative regulation of secondary metabolite biosynthetic processGO:190037720.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
insulin like growth factor receptor signaling pathwayGO:0048009210.012
placenta developmentGO:00018901400.012
b cell activationGO:00421131610.012
positive regulation of cell cycle processGO:0090068610.012
regulation of vesicle mediated transportGO:00606271390.012
regulation of cell cycleGO:00517262810.012
regulation of ion transmembrane transportGO:00347651190.012
regulation of response to woundingGO:19030341890.012
glycoprotein metabolic processGO:00091001160.012
cellular response to cytokine stimulusGO:00713451890.012
amide transportGO:00428861380.012
regulation of carbohydrate metabolic processGO:0006109750.012
atp catabolic processGO:0006200550.012
regulation of protein serine threonine kinase activityGO:00719001570.012
protein autophosphorylationGO:0046777610.012
Human
cardiac ventricle developmentGO:0003231830.012
gastrulationGO:00073691160.012
ossificationGO:00015032160.012
regulation of defense responseGO:00313472330.012
cell activation involved in immune responseGO:00022631260.012
engulfment of apoptotic cellGO:004365230.012
negative regulation of growthGO:0045926990.012
regulation of map kinase activityGO:00434051200.012
regulation of jak stat cascadeGO:0046425340.012
cellular metal ion homeostasisGO:00068751510.011
positive regulation of gtp catabolic processGO:0033126850.011
calcium ion transmembrane transportGO:0070588850.011
stem cell differentiationGO:00488632680.011
muscle contractionGO:00069361010.011
angiogenesisGO:00015252010.011
organ growthGO:00352651170.011
cellular response to acid chemicalGO:0071229680.011
dephosphorylationGO:00163111290.011
nucleoside monophosphate metabolic processGO:0009123850.011
sensory organ morphogenesisGO:00905962420.011
sequestering of calcium ionGO:0051208180.011
second messenger mediated signalingGO:0019932730.011
neuron apoptotic processGO:00514021420.011
negative regulation of lymphocyte activationGO:0051250910.011
establishment of protein localization to organelleGO:00725941180.011
regulation of cell substrate adhesionGO:0010810730.011
monocarboxylic acid metabolic processGO:00327871910.011
negative regulation of intracellular signal transductionGO:19025321670.011
gene silencing by rnaGO:0031047190.011
cation homeostasisGO:00550802120.011
circulatory system processGO:00030131970.011
inflammatory responseGO:00069542440.011
leukocyte differentiationGO:00025213420.011
protein targetingGO:00066051430.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
regulation of voltage gated calcium channel activityGO:190138540.011
cell junction assemblyGO:0034329520.011
regulation of secretionGO:00510462740.011
positive regulation of nuclear divisionGO:0051785270.011
leukocyte activation involved in immune responseGO:00023661260.011
positive regulation of protein complex assemblyGO:0031334450.011
regulation of multi organism processGO:00439001110.011
regulation of dendritic cell apoptotic processGO:200066830.011
ear developmentGO:00435832000.011
lung developmentGO:00303241640.011
male sex differentiationGO:00466611090.011
apical constrictionGO:000338340.011
bone developmentGO:00603481200.011
cerebral cortex developmentGO:0021987860.011
locomotory behaviorGO:00076261950.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
leukocyte migrationGO:00509001240.011
hormone metabolic processGO:0042445860.011
protein maturationGO:00516041760.011
regulation of lipid metabolic processGO:00192161180.011
metal ion homeostasisGO:00550651890.010
cell fate commitmentGO:00451652100.010
cell junction organizationGO:0034330770.010
positive regulation of transferase activityGO:00513471670.010
response to inorganic substanceGO:0010035960.010
histone deubiquitinationGO:001657820.010
cognitionGO:00508901490.010
retrograde transport endosome to golgiGO:004214720.010
cellular response to amino acid stimulusGO:0071230290.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
blood circulationGO:00080151950.010
negative regulation of protein phosphorylationGO:00019331260.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
substrate dependent cell migration cell extensionGO:000693040.010
regulation of peptidyl serine phosphorylationGO:0033135390.010
development of primary sexual characteristicsGO:00451371430.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
intracellular steroid hormone receptor signaling pathwayGO:0030518290.010
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.010
regulation of erk1 and erk2 cascadeGO:0070372710.010
sequestering of metal ionGO:0051238190.010
regulation of system processGO:00440572000.010
multicellular organismal homeostasisGO:00488711640.010
regulation of reactive oxygen species metabolic processGO:2000377400.010

Smg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.021
organ system cancerDOID:005068600.021
disease of cellular proliferationDOID:1456600.021
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
musculoskeletal system diseaseDOID:1700.012
immune system diseaseDOID:291400.011
osteochondrodysplasiaDOID:225600.011
bone development diseaseDOID:008000600.011
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011