Mus musculus

8 known processes

Srxn1

sulfiredoxin 1 homolog (S. cerevisiae)

(Aliases: TX01,AW488194,AI854065,1700127B04Rik,Npn3,Srx,Srx1)

Srxn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.313
oxidation reduction processGO:00551143420.129
glutathione metabolic processGO:0006749160.099
cellular amide metabolic processGO:0043603580.089
cellular lipid metabolic processGO:00442553230.081
peptide metabolic processGO:0006518460.077
response to oxidative stressGO:00069791230.075
cellular modified amino acid metabolic processGO:0006575630.075
sulfur compound metabolic processGO:00067901000.067
apoptotic signaling pathwayGO:00971903060.063
cation transportGO:00068123990.059
male gamete generationGO:00482322850.057
cellular ketone metabolic processGO:0042180840.055
amine metabolic processGO:0009308450.052
negative regulation of cellular protein metabolic processGO:00322692470.052
cellular amine metabolic processGO:0044106440.047
negative regulation of protein metabolic processGO:00512482820.046
regulation of cellular amine metabolic processGO:0033238200.045
spermatogenesisGO:00072832840.042
protein modification by small protein conjugationGO:00324461870.041
regulation of cellular amino acid metabolic processGO:000652150.041
macromolecule catabolic processGO:00090572810.040
positive regulation of cellular amine metabolic processGO:003324050.039
negative regulation of intracellular signal transductionGO:19025321670.039
negative regulation of protein modification processGO:00314001630.037
nucleobase containing small molecule metabolic processGO:00550863520.037
positive regulation of cellular amino acid metabolic processGO:004576430.035
regulation of cytokine productionGO:00018172660.034
transmembrane transportGO:00550854120.034
response to inorganic substanceGO:0010035960.033
positive regulation of cell deathGO:00109422240.033
positive regulation of protein phosphorylationGO:00019342420.033
alpha amino acid metabolic processGO:1901605590.032
regulation of transferase activityGO:00513382630.032
protein modification by small protein conjugation or removalGO:00706472070.031
cytokine productionGO:00018163190.031
glycerolipid metabolic processGO:00464861220.031
inflammatory responseGO:00069542440.031
monocarboxylic acid metabolic processGO:00327871910.031
nucleoside phosphate metabolic processGO:00067533380.029
regulation of cellular ketone metabolic processGO:0010565660.029
cellular homeostasisGO:00197252400.029
response to extracellular stimulusGO:00099911270.029
regulation of apoptotic signaling pathwayGO:20012331970.028
organonitrogen compound catabolic processGO:19015652640.028
ion transmembrane transportGO:00342203610.028
organic cyclic compound catabolic processGO:19013612950.028
positive regulation of protein modification processGO:00314012990.028
serine family amino acid metabolic processGO:000906970.028
cofactor metabolic processGO:0051186800.027
cytoplasmic transportGO:00164822340.027
response to organic cyclic compoundGO:00140701980.027
organic anion transportGO:00157111370.027
organonitrogen compound biosynthetic processGO:19015661920.026
cellular ion homeostasisGO:00068731650.026
response to reactive oxygen speciesGO:0000302560.026
selenium compound metabolic processGO:000188730.026
intracellular protein transportGO:00068862040.026
nitrogen compound transportGO:00717052710.026
peptidyl amino acid modificationGO:00181933360.026
reactive oxygen species metabolic processGO:0072593840.026
regulation of membrane potentialGO:00423911920.026
purine nucleotide metabolic processGO:00061633020.026
cellular macromolecule catabolic processGO:00442652060.026
chemotaxisGO:00069352470.025
regulation of mapk cascadeGO:00434082480.025
negative regulation of phosphorus metabolic processGO:00105631840.025
negative regulation of protein phosphorylationGO:00019331260.025
organic acid transportGO:00158491010.025
establishment or maintenance of cytoskeleton polarityGO:003095220.024
maintenance of locationGO:0051235890.024
proteolysis involved in cellular protein catabolic processGO:00516031470.024
sensory perceptionGO:00076002450.024
cation transmembrane transportGO:00986552660.024
aromatic compound catabolic processGO:00194392860.024
skeletal system developmentGO:00015013560.024
negative regulation of molecular functionGO:00440922580.023
mapk cascadeGO:00001652810.023
cell adhesionGO:00071553290.023
locomotory behaviorGO:00076261950.023
divalent metal ion transportGO:00708381720.022
placenta developmentGO:00018901400.022
membrane organizationGO:00610242450.022
dephosphorylationGO:00163111290.022
purine ribonucleoside metabolic processGO:00461282410.022
negative regulation of cellular amino acid metabolic processGO:004576300.022
nucleotide metabolic processGO:00091173320.022
regulation of protein serine threonine kinase activityGO:00719001570.022
regulation of organelle organizationGO:00330432890.021
wound healingGO:00420601570.021
regulation of defense responseGO:00313472330.021
carboxylic acid biosynthetic processGO:0046394860.021
regulation of reactive oxygen species metabolic processGO:2000377400.021
cellular protein catabolic processGO:00442571550.021
adult behaviorGO:00305341350.021
response to oxygen levelsGO:0070482620.021
fertilizationGO:00095661270.021
muscle cell differentiationGO:00426922610.021
small molecule biosynthetic processGO:00442831320.021
modification dependent protein catabolic processGO:00199411330.021
cellular metal ion homeostasisGO:00068751510.021
fatty acid metabolic processGO:00066311210.021
regulation of kinase activityGO:00435492490.020
negative regulation of cellular amine metabolic processGO:003323910.020
inorganic cation transmembrane transportGO:00986622070.020
protein catabolic processGO:00301632210.020
response to nutrient levelsGO:00316671090.020
regulation of cell activationGO:00508652890.020
cellular chemical homeostasisGO:00550822150.020
cellular amino acid biosynthetic processGO:0008652220.020
microtubule based processGO:00070172360.020
regulation of cell cycleGO:00517262810.020
regulation of cellular catabolic processGO:00313292420.020
cellular response to dna damage stimulusGO:00069742070.020
retrograde transport endosome to golgiGO:004214720.019
compound eye developmentGO:004874910.019
carboxylic acid transportGO:00469421000.019
negative regulation of phosphate metabolic processGO:00459361840.019
protein ubiquitinationGO:00165671710.019
divalent inorganic cation homeostasisGO:00725071380.019
nucleoside metabolic processGO:00091162460.019
regulation of ion transportGO:00432692150.019
blood circulationGO:00080151950.019
regulation of hormone levelsGO:00108172110.019
lipid biosynthetic processGO:00086101790.019
protein targetingGO:00066051430.019
lipid transportGO:0006869980.019
organic hydroxy compound metabolic processGO:19016152030.019
kidney developmentGO:00018222130.019
response to organonitrogen compoundGO:00102432460.019
cellular nitrogen compound catabolic processGO:00442702800.019
cell type specific apoptotic processGO:00972852680.019
organic acid biosynthetic processGO:0016053860.019
positive regulation of macroautophagyGO:001623930.019
regulation of secretionGO:00510462740.018
response to acid chemicalGO:00011011110.018
coenzyme metabolic processGO:0006732520.018
metal ion homeostasisGO:00550651890.018
dna metabolic processGO:00062593030.018
regulation of cellular response to stressGO:00801351590.018
cellular response to lipidGO:00713961450.018
extracellular matrix organizationGO:00301981470.018
ear developmentGO:00435832000.018
cation homeostasisGO:00550802120.018
positive regulation of apoptotic processGO:00430652170.018
inorganic ion transmembrane transportGO:00986602340.018
positive regulation of necrotic cell deathGO:001094010.018
organophosphate catabolic processGO:00464342320.018
muscle tissue developmentGO:00605373080.018
blood vessel morphogenesisGO:00485142850.018
spermatid differentiationGO:00485151150.018
sequestering of calcium ionGO:0051208180.018
anion transportGO:00068201770.018
negative regulation of phosphorylationGO:00423261660.018
t cell activationGO:00421102890.018
protein oligomerizationGO:0051259670.017
negative regulation of cellular component organizationGO:00511291940.017
sequestering of metal ionGO:0051238190.017
regulation of protein kinase activityGO:00458592320.017
divalent inorganic cation transportGO:00725111780.017
endomembrane system organizationGO:00102561470.017
myeloid cell differentiationGO:00300992330.017
defense response to other organismGO:00985421970.017
regulation of protein localizationGO:00328802310.017
glycoprotein metabolic processGO:00091001160.017
cellular response to oxidative stressGO:0034599760.017
reactive nitrogen species metabolic processGO:200105700.017
leukocyte migrationGO:00509001240.017
protein maturationGO:00516041760.017
germ cell developmentGO:00072811850.017
digestive system developmentGO:00551232000.017
muscle contractionGO:00069361010.017
regulation of cell motilityGO:20001452360.017
synaptic transmissionGO:00072683290.016
regulation of homeostatic processGO:00328441820.016
glycerophospholipid metabolic processGO:0006650710.016
axonogenesisGO:00074092740.016
circulatory system processGO:00030131970.016
sensory organ morphogenesisGO:00905962420.016
negative regulation of transferase activityGO:0051348850.016
cell chemotaxisGO:0060326810.016
ras protein signal transductionGO:0007265770.016
cellular response to inorganic substanceGO:0071241370.016
exocytosisGO:00068871210.016
purine ribonucleotide metabolic processGO:00091502900.016
nonribosomal peptide biosynthetic processGO:001918450.016
small gtpase mediated signal transductionGO:0007264970.016
spermatid developmentGO:00072861080.016
modification dependent macromolecule catabolic processGO:00436321330.016
heterocycle catabolic processGO:00467002800.016
positive regulation of cell developmentGO:00107202370.016
renal system developmentGO:00720012250.016
sulfur compound biosynthetic processGO:0044272370.016
regulation of cytoplasmic transportGO:19036491120.016
response to peptide hormoneGO:00434341270.016
multi multicellular organism processGO:00447061090.016
lipid localizationGO:00108761260.016
regulation of response to woundingGO:19030341890.016
single organism cell adhesionGO:00986021560.016
positive regulation of cellular catabolic processGO:00313311480.016
ribose phosphate metabolic processGO:00196932910.016
regulation of establishment of protein localizationGO:00702011810.015
cellular response to external stimulusGO:0071496880.015
steroid metabolic processGO:00082021190.015
protein localization to organelleGO:00333651850.015
mitochondrion organizationGO:00070051340.015
muscle system processGO:00030121410.015
proteasomal protein catabolic processGO:0010498980.015
actin cytoskeleton organizationGO:00300362200.015
organelle localizationGO:00516401790.015
fat cell differentiationGO:00454441600.015
phospholipid metabolic processGO:0006644870.015
carbohydrate derivative catabolic processGO:19011362310.015
cell substrate adhesionGO:00315891300.015
regulation of cell adhesionGO:00301551540.015
purine containing compound metabolic processGO:00725213110.015
cellular response to arsenic containing substanceGO:007124340.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
microtubule cytoskeleton organizationGO:00002261570.015
g protein coupled receptor signaling pathwayGO:00071862430.015
purine containing compound catabolic processGO:00725232130.015
engulfment of apoptotic cellGO:004365230.015
regulation of cell migrationGO:00303342190.015
skeletal muscle organ developmentGO:00605381630.015
response to peptideGO:19016521360.015
response to radiationGO:00093141650.015
gland developmentGO:00487323300.015
positive regulation of programmed cell deathGO:00430682180.015
nucleoside phosphate catabolic processGO:19012922220.015
regulation of secretion by cellGO:19035302490.015
immune effector processGO:00022523210.015
homeostasis of number of cellsGO:00488722100.014
posttranscriptional regulation of gene expressionGO:00106081550.014
hematopoietic progenitor cell differentiationGO:00022441430.014
second messenger mediated signalingGO:0019932730.014
ribonucleoside metabolic processGO:00091192450.014
leukocyte differentiationGO:00025213420.014
carbohydrate metabolic processGO:00059752300.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
regulation of cellular component biogenesisGO:00440871810.014
nucleoside triphosphate metabolic processGO:00091412300.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
regulation of cellular component sizeGO:00325351210.014
regulation of protein transportGO:00512231630.014
cellular component assembly involved in morphogenesisGO:00109271390.014
protein processingGO:00164851630.014
neuronal action potentialGO:0019228540.014
small molecule catabolic processGO:0044282710.014
oocyte constructionGO:000730820.014
nucleocytoplasmic transportGO:00069131390.014
cellular response to hormone stimulusGO:00328701500.014
carbohydrate derivative biosynthetic processGO:19011371830.014
camera type eye developmentGO:00430102660.014
regionalizationGO:00030023370.014
cellular response to organonitrogen compoundGO:00714171450.014
positive regulation of nervous system developmentGO:00519622210.014
regulation of lymphocyte activationGO:00512492400.014
lipoprotein metabolic processGO:0042157430.014
positive regulation of organelle organizationGO:00106381280.014
regulation of map kinase activityGO:00434051200.014
regulation of body fluid levelsGO:00508781620.013
extracellular structure organizationGO:00430621480.013
oocyte axis specificationGO:000730920.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
substantia nigra developmentGO:002176220.013
lipid modificationGO:0030258650.013
cellular calcium ion homeostasisGO:00068741190.013
rho protein signal transductionGO:0007266320.013
organelle assemblyGO:00709251770.013
multicellular organismal signalingGO:0035637910.013
peptidyl tyrosine modificationGO:00182121450.013
cellular protein complex assemblyGO:00436231160.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
ribonucleotide metabolic processGO:00092592910.013
regulation of inflammatory responseGO:00507271470.013
muscle cell developmentGO:00550011330.013
innate immune responseGO:00450871570.013
cognitionGO:00508901490.013
response to endoplasmic reticulum stressGO:0034976530.013
purine nucleotide catabolic processGO:00061952110.013
calcium ion transportGO:00068161590.013
positive regulation of homeostatic processGO:0032846640.013
transition metal ion transportGO:0000041380.013
amide transportGO:00428861380.013
purine ribonucleoside catabolic processGO:00461302050.013
signal transduction by p53 class mediatorGO:0072331510.013
regulation of multi organism processGO:00439001110.013
regulation of system processGO:00440572000.013
response to lipopolysaccharideGO:00324961280.013
regulation of proteolysisGO:00301621640.013
negative regulation of proteolysisGO:0045861740.013
production of molecular mediator of immune responseGO:00024401030.013
regulation of vesicle mediated transportGO:00606271390.013
regulation of transmembrane transportGO:00347621280.013
striated muscle tissue developmentGO:00147062930.013
calcium ion homeostasisGO:00550741270.013
organic hydroxy compound transportGO:0015850930.013
regulation of cytoskeleton organizationGO:00514931220.012
negative regulation of immune system processGO:00026832090.012
peptide transportGO:00158331330.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
striated muscle cell developmentGO:00550021250.012
reactive oxygen species biosynthetic processGO:190340980.012
nuclear transportGO:00511691390.012
hormone secretionGO:00468791280.012
response to vitamin aGO:003318910.012
cellular response to extracellular stimulusGO:0031668810.012
regulation of protein catabolic processGO:00421761080.012
cellular response to peptide hormone stimulusGO:0071375920.012
ubiquitin dependent protein catabolic processGO:00065111290.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
lateral inhibitionGO:004633110.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
nucleoside monophosphate metabolic processGO:0009123850.012
regulation of endopeptidase activityGO:0052548890.012
developmental maturationGO:00217001930.012
alcohol metabolic processGO:00060661160.012
regulation of cell cycle processGO:00105641600.012
action potentialGO:0001508780.012
cellular response to cytokine stimulusGO:00713451890.012
positive regulation of protein kinase activityGO:00458601440.012
leukocyte mediated immunityGO:00024431740.012
regulation of hydrolase activityGO:00513362460.012
dendritic spine maintenanceGO:009706240.012
cellular response to lipopolysaccharideGO:0071222770.012
nucleoside triphosphate catabolic processGO:00091432050.012
endocytosisGO:00068971680.012
forebrain developmentGO:00309003020.012
negative regulation of protein processingGO:0010955790.012
ossificationGO:00015032160.012
cell growthGO:00160491300.012
epithelial cell developmentGO:00020641590.012
positive regulation of cell activationGO:00508671580.012
positive regulation of secretionGO:00510471300.012
lipid catabolic processGO:0016042690.012
l amino acid transportGO:0015807320.012
regulation of protein maturationGO:1903317960.012
protein importGO:00170381010.011
regulation of peptidase activityGO:0052547960.011
amino acid transmembrane transportGO:0003333370.011
response to ischemiaGO:0002931140.011
leukocyte chemotaxisGO:0030595690.011
cytokine biosynthetic processGO:0042089680.011
glycoprotein biosynthetic processGO:0009101890.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
maternal determination of anterior posterior axis embryoGO:000835820.011
organelle fissionGO:00482851700.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
myeloid cell homeostasisGO:00022621140.011
actin filament organizationGO:00070151130.011
regulation of protein processingGO:0070613960.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
amino acid transportGO:0006865610.011
response to molecule of bacterial originGO:00022371430.011
angiogenesisGO:00015252010.011
leukocyte proliferationGO:00706611720.011
organic hydroxy compound biosynthetic processGO:1901617770.011
establishment of protein localization to organelleGO:00725941180.011
glycosyl compound metabolic processGO:19016572460.011
glial cell differentiationGO:00100011310.011
regulation of purine nucleotide metabolic processGO:19005421690.011
purine nucleoside metabolic processGO:00422782410.011
cytokine metabolic processGO:0042107710.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
glycosyl compound catabolic processGO:19016582060.011
i kappab kinase nf kappab signalingGO:0007249850.011
plasma membrane organizationGO:0007009900.011
olfactory learningGO:000835520.011
cellular response to molecule of bacterial originGO:0071219830.011
cellular response to growth factor stimulusGO:00713631970.011
b cell activationGO:00421131610.011
regulation of neuron deathGO:19012141340.011
regulation of intracellular transportGO:00323861590.011
sphingolipid metabolic processGO:0006665450.011
nucleoside catabolic processGO:00091642060.011
ribonucleoside catabolic processGO:00424542060.011
response to drugGO:0042493750.011
response to light stimulusGO:00094161350.011
membrane lipid metabolic processGO:0006643530.011
positive regulation of mapk cascadeGO:00434101700.011
phosphatidylinositol metabolic processGO:0046488450.011
intracellular mrna localizationGO:000829840.011
digestive tract morphogenesisGO:00485461470.011
organ growthGO:00352651170.011
cell maturationGO:00484691270.011
cellular response to cadmium ionGO:007127630.011
peptidyl tyrosine phosphorylationGO:00181081430.011
cellular lipid catabolic processGO:0044242520.011
lymphocyte proliferationGO:00466511640.011
peptide secretionGO:00027901140.011
skin developmentGO:00435882200.011
nuclear importGO:0051170950.011
response to growth factorGO:00708481980.011
regulation of anatomical structure sizeGO:00900661780.011
defense response to bacteriumGO:00427421190.011
response to insulinGO:00328681000.011
positive regulation of hydrolase activityGO:00513451480.011
transmission of nerve impulseGO:0019226760.010
lymphocyte differentiationGO:00300982420.010
adaptive immune responseGO:00022501550.010
cellularizationGO:000734910.010
epidermis developmentGO:00085441870.010
protein localization to nucleusGO:00345041210.010
positive regulation of lymphocyte activationGO:00512511400.010
positive regulation of cytokine productionGO:00018191740.010
microglia developmentGO:001400520.010
response to oxygen radicalGO:0000305160.010
hormone metabolic processGO:0042445860.010
negative regulation of protein maturationGO:1903318790.010
response to steroid hormoneGO:0048545560.010
rhythmic processGO:00485111740.010
regulation of cell projection organizationGO:00313442060.010
regulation of fat cell differentiationGO:0045598810.010
regulation of neuron apoptotic processGO:00435231220.010
learning or memoryGO:00076111480.010
digestive tract developmentGO:00485651900.010
striated muscle myosin thick filament assemblyGO:007168810.010
regulation of intracellular protein transportGO:0033157820.010

Srxn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
neuropathyDOID:87000.032
musculoskeletal system diseaseDOID:1700.030
neuromuscular diseaseDOID:44000.024
organ system cancerDOID:005068600.019
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
connective tissue diseaseDOID:6500.018
charcot marie tooth diseaseDOID:1059500.017
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.015
bone diseaseDOID:008000100.013
immune system diseaseDOID:291400.012
central nervous system diseaseDOID:33100.012
neurodegenerative diseaseDOID:128900.010