IMP: Integrative Multi-species Prediction

Mus musculus

138 known processes

Celsr1

cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)

(Aliases: crash,Crsh,Scy)

Entrez: 12614
Ensembl: ENSMUSG00000016028
UniProtKB: O35161

Process Predictions
Disease Predictions

Celsr1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryonic organ morphogenesis	GO:0048562	276	0.826
epithelial tube morphogenesis	GO:0060562	303	0.817
skin development	GO:0043588	220	0.584
regionalization	GO:0003002	337	0.523
embryonic epithelial tube formation	GO:0001838	130	0.521
sensory organ morphogenesis	GO:0090596	242	0.490
establishment of tissue polarity	GO:0007164	28	0.386
neural tube development	GO:0021915	160	0.377
regulation of establishment of planar polarity	GO:0090175	28	0.363
cell adhesion	GO:0007155	329	0.356	Mouse Fly
morphogenesis of a polarized epithelium	GO:0001738	37	0.352
ear morphogenesis	GO:0042471	118	0.352
epidermis development	GO:0008544	187	0.330
ear development	GO:0043583	200	0.330
inner ear morphogenesis	GO:0042472	101	0.311
rho protein signal transduction	GO:0007266	32	0.309
gland development	GO:0048732	330	0.307
regulation of organ morphogenesis	GO:2000027	144	0.281
negative regulation of cell proliferation	GO:0008285	296	0.280
canonical wnt signaling pathway	GO:0060070	130	0.270
regulation of kinase activity	GO:0043549	249	0.269
regulation of cellular ketone metabolic process	GO:0010565	66	0.266
response to acid chemical	GO:0001101	111	0.249
morphogenesis of embryonic epithelium	GO:0016331	159	0.245
lymphocyte differentiation	GO:0030098	242	0.238
non canonical wnt signaling pathway	GO:0035567	33	0.224
skeletal system development	GO:0001501	356	0.222
establishment of planar polarity	GO:0001736	28	0.214
camera type eye development	GO:0043010	266	0.206
primary neural tube formation	GO:0014020	95	0.204
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.202
tube formation	GO:0035148	140	0.201
germ cell development	GO:0007281	185	0.199
wnt signaling pathway	GO:0016055	188	0.198
stem cell development	GO:0048864	219	0.198
cellular amine metabolic process	GO:0044106	44	0.192
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.189
neural tube closure	GO:0001843	90	0.184
regulation of cell adhesion	GO:0030155	154	0.184
regulation of cellular amino acid metabolic process	GO:0006521	5	0.180
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.179
single organismal cell cell adhesion	GO:0016337	131	0.179
cellular ketone metabolic process	GO:0042180	84	0.177
regulation of cellular amine metabolic process	GO:0033238	20	0.170
respiratory tube development	GO:0030323	167	0.166
blood vessel morphogenesis	GO:0048514	285	0.163
segmentation	GO:0035282	93	0.158	Fly
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.155	Mouse Fly
neural tube formation	GO:0001841	108	0.154
single organism cell adhesion	GO:0098602	156	0.152
epithelial tube formation	GO:0072175	130	0.151
epithelial cell proliferation	GO:0050673	174	0.148
male gamete generation	GO:0048232	285	0.145
embryonic placenta development	GO:0001892	98	0.144
cellular amino acid metabolic process	GO:0006520	103	0.142
muscle cell differentiation	GO:0042692	261	0.140
negative regulation of molecular function	GO:0044092	258	0.139
regulation of canonical wnt signaling pathway	GO:0060828	82	0.138
spermatogenesis	GO:0007283	284	0.137
forebrain development	GO:0030900	302	0.136
digestive tract development	GO:0048565	190	0.134	Zebrafish
cellular homeostasis	GO:0019725	240	0.131
stem cell maintenance	GO:0019827	130	0.129
respiratory system development	GO:0060541	190	0.127
regulation of cell activation	GO:0050865	289	0.127
actin filament organization	GO:0007015	113	0.127
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	GO:0060489	2	0.126
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.125	Fly
mapk cascade	GO:0000165	281	0.124
cardiac chamber morphogenesis	GO:0003206	93	0.124
regulation of hydrolase activity	GO:0051336	246	0.123
regulation of cell migration	GO:0030334	219	0.123
axon guidance	GO:0007411	141	0.121	Fly
protein maturation	GO:0051604	176	0.120
leukocyte differentiation	GO:0002521	342	0.120
locomotory behavior	GO:0007626	195	0.118
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.117
regulation of establishment of planar polarity involved in neural tube closure	GO:0090178	15	0.117
amine metabolic process	GO:0009308	45	0.116
response to nutrient levels	GO:0031667	109	0.115
wound healing	GO:0042060	157	0.115
cell cell adhesion	GO:0098609	41	0.113	Mouse Fly
positive regulation of rho gtpase activity	GO:0032321	41	0.111
gastrulation	GO:0007369	116	0.108	Zebrafish
striated muscle tissue development	GO:0014706	293	0.108
appendage morphogenesis	GO:0035107	149	0.108
t cell activation	GO:0042110	289	0.105
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.102
embryonic skeletal system morphogenesis	GO:0048704	91	0.102
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.101
cognition	GO:0050890	149	0.100
cell fate commitment	GO:0045165	210	0.100
regulation of neuron differentiation	GO:0045664	281	0.098	Fly
regulation of cell motility	GO:2000145	236	0.094
peptidyl amino acid modification	GO:0018193	336	0.094
protein targeting	GO:0006605	143	0.094
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.093
regulation of wnt signaling pathway	GO:0030111	123	0.092
epithelial cell development	GO:0002064	159	0.091
morphogenesis of a branching structure	GO:0001763	203	0.091
chemotaxis	GO:0006935	247	0.090	Fly
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.090
lung development	GO:0030324	164	0.088
regulation of mapk cascade	GO:0043408	248	0.087
positive regulation of mapk cascade	GO:0043410	170	0.086
digestive system development	GO:0055123	200	0.085	Zebrafish
negative regulation of protein metabolic process	GO:0051248	282	0.085
regulation of cellular catabolic process	GO:0031329	242	0.085
response to organonitrogen compound	GO:0010243	246	0.085
hindbrain development	GO:0030902	128	0.085
sensory perception	GO:0007600	245	0.084
sensory perception of sound	GO:0007605	97	0.084
neuron migration	GO:0001764	122	0.083
tube closure	GO:0060606	91	0.081
blood circulation	GO:0008015	195	0.079
ras protein signal transduction	GO:0007265	77	0.079
nucleoside phosphate metabolic process	GO:0006753	338	0.079
regulation of actin cytoskeleton organization	GO:0032956	84	0.079
digestive tract morphogenesis	GO:0048546	147	0.078	Zebrafish
cellular component assembly involved in morphogenesis	GO:0010927	139	0.078	Mouse
metal ion homeostasis	GO:0055065	189	0.078
t cell differentiation	GO:0030217	174	0.078
cellular response to lipid	GO:0071396	145	0.077
regulation of embryonic development	GO:0045995	71	0.077
regulation of cell cycle	GO:0051726	281	0.077
positive regulation of growth	GO:0045927	104	0.076
gtp catabolic process	GO:0006184	143	0.076
establishment or maintenance of apical basal cell polarity	GO:0035088	21	0.075
regulation of neuron projection development	GO:0010975	169	0.075	Fly
cellular response to organonitrogen compound	GO:0071417	145	0.074
regulation of rho gtpase activity	GO:0032319	58	0.074
morphogenesis of a branching epithelium	GO:0061138	193	0.074
oocyte axis specification	GO:0007309	2	0.073
skeletal muscle organ development	GO:0060538	163	0.073
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.073
oogenesis	GO:0048477	56	0.072
hair cell differentiation	GO:0035315	40	0.072
purine ribonucleotide metabolic process	GO:0009150	290	0.072
negative regulation of wnt signaling pathway	GO:0030178	73	0.071
macromolecule catabolic process	GO:0009057	281	0.070
angiogenesis	GO:0001525	201	0.070
developmental maturation	GO:0021700	193	0.070
embryonic appendage morphogenesis	GO:0035113	126	0.069
negative regulation of cell development	GO:0010721	169	0.068
lateral line system development	GO:0048925	1	0.068
cytokine mediated signaling pathway	GO:0019221	115	0.067
regulation of homeostatic process	GO:0032844	182	0.067
limb development	GO:0060173	166	0.066
formation of radial glial scaffolds	GO:0021943	4	0.066
peptidyl tyrosine modification	GO:0018212	145	0.066
cation homeostasis	GO:0055080	212	0.066
pallium development	GO:0021543	120	0.066
nucleoside phosphate catabolic process	GO:1901292	222	0.065
leukocyte proliferation	GO:0070661	172	0.065
placenta blood vessel development	GO:0060674	31	0.065
muscular septum morphogenesis	GO:0003150	4	0.065
renal system development	GO:0072001	225	0.065
branching morphogenesis of an epithelial tube	GO:0048754	159	0.064
muscle cell development	GO:0055001	133	0.064
kidney development	GO:0001822	213	0.063
neuron projection guidance	GO:0097485	141	0.063	Fly
somitogenesis	GO:0001756	69	0.063
positive regulation of cellular amine metabolic process	GO:0033240	5	0.062
protein processing	GO:0016485	163	0.062
regulation of nucleotide metabolic process	GO:0006140	169	0.062
regulation of lymphocyte activation	GO:0051249	240	0.062
response to extracellular stimulus	GO:0009991	127	0.062
cellular chemical homeostasis	GO:0055082	215	0.062
heart morphogenesis	GO:0003007	178	0.061
axonogenesis	GO:0007409	274	0.061	Fly
apoptotic signaling pathway	GO:0097190	306	0.061
cellular lipid metabolic process	GO:0044255	323	0.061
ribonucleotide metabolic process	GO:0009259	291	0.059
regulation of protein kinase activity	GO:0045859	232	0.059
axis elongation involved in somitogenesis	GO:0090245	4	0.059
cellular response to acid chemical	GO:0071229	68	0.059
intracellular protein transport	GO:0006886	204	0.059
nucleobase containing small molecule metabolic process	GO:0055086	352	0.058
placenta development	GO:0001890	140	0.058
synapse organization	GO:0050808	125	0.058	Fly
stem cell differentiation	GO:0048863	268	0.058
salivary gland morphogenesis	GO:0007435	33	0.057
regulation of purine nucleotide metabolic process	GO:1900542	169	0.057
cardiac chamber development	GO:0003205	108	0.057
skeletal system morphogenesis	GO:0048705	203	0.057
mammary gland epithelium development	GO:0061180	65	0.057
nucleocytoplasmic transport	GO:0006913	139	0.056
planar cell polarity pathway involved in neural tube closure	GO:0090179	14	0.056
regulation of membrane potential	GO:0042391	192	0.056
regulation of organelle organization	GO:0033043	289	0.055
insulin secretion	GO:0030073	89	0.055
establishment or maintenance of bipolar cell polarity	GO:0061245	21	0.055
circulatory system process	GO:0003013	197	0.055
rhythmic process	GO:0048511	174	0.055
multicellular organismal signaling	GO:0035637	91	0.055
regulation of map kinase activity	GO:0043405	120	0.054
action potential	GO:0001508	78	0.054
posttranscriptional regulation of gene expression	GO:0010608	155	0.054
mechanoreceptor differentiation	GO:0042490	67	0.054
cellular response to biotic stimulus	GO:0071216	92	0.053
nitrogen compound transport	GO:0071705	271	0.053
negative regulation of hydrolase activity	GO:0051346	71	0.053
somatic stem cell maintenance	GO:0035019	47	0.053
formation of primary germ layer	GO:0001704	77	0.053
negative regulation of immune system process	GO:0002683	209	0.053
oocyte construction	GO:0007308	2	0.052
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.052
cellular response to growth factor stimulus	GO:0071363	197	0.052
nucleoside triphosphate catabolic process	GO:0009143	205	0.052
amide transport	GO:0042886	138	0.051
immune effector process	GO:0002252	321	0.051
lymphocyte proliferation	GO:0046651	164	0.051
regulation of gtp catabolic process	GO:0033124	113	0.051
regulation of secretion	GO:0051046	274	0.051
positive regulation of programmed cell death	GO:0043068	218	0.051
organic anion transport	GO:0015711	137	0.050
establishment or maintenance of cell polarity	GO:0007163	86	0.050	Fly
central nervous system morphogenesis	GO:0021551	2	0.050
guanosine containing compound catabolic process	GO:1901069	144	0.050
embryonic heart tube development	GO:0035050	65	0.050
purine nucleoside metabolic process	GO:0042278	241	0.049
nucleotide metabolic process	GO:0009117	332	0.049
protein localization to nucleus	GO:0034504	121	0.049
negative regulation of bmp signaling pathway	GO:0030514	35	0.049
actin cytoskeleton organization	GO:0030036	220	0.048
detection of stimulus involved in sensory perception	GO:0050906	44	0.048
motor neuron axon guidance	GO:0008045	26	0.048
limb morphogenesis	GO:0035108	149	0.048
peptidyl tyrosine phosphorylation	GO:0018108	143	0.047
developmental growth involved in morphogenesis	GO:0060560	138	0.047
transmission of nerve impulse	GO:0019226	76	0.047
purine ribonucleotide catabolic process	GO:0009154	208	0.047
cellular response to dna damage stimulus	GO:0006974	207	0.047
heterocycle catabolic process	GO:0046700	280	0.047
synaptic transmission	GO:0007268	329	0.047	Fly
stem cell proliferation	GO:0072089	117	0.047
positive regulation of map kinase activity	GO:0043406	84	0.047
positive regulation of nervous system development	GO:0051962	221	0.047
negative regulation of cellular protein metabolic process	GO:0032269	247	0.047
blastocyst development	GO:0001824	80	0.046
muscle tissue development	GO:0060537	308	0.046
response to growth factor	GO:0070848	198	0.046
peptide transport	GO:0015833	133	0.046
nucleoside catabolic process	GO:0009164	206	0.046
t cell proliferation	GO:0042098	120	0.046
non canonical wnt signaling pathway via jnk cascade	GO:0038031	3	0.046
positive regulation of ras gtpase activity	GO:0032320	65	0.046
nucleoside metabolic process	GO:0009116	246	0.045
negative regulation of lymphocyte activation	GO:0051250	91	0.045
actin filament bundle assembly	GO:0051017	40	0.045
regulation of cellular component biogenesis	GO:0044087	181	0.045	Fly
regulation of cell projection organization	GO:0031344	206	0.045	Fly
polarity specification of proximal distal axis	GO:0010085	2	0.045
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.044
cochlea development	GO:0090102	35	0.044
connective tissue development	GO:0061448	179	0.044
monocarboxylic acid metabolic process	GO:0032787	191	0.044
inorganic cation transmembrane transport	GO:0098662	207	0.044
regulation of purine nucleotide catabolic process	GO:0033121	122	0.044
oviduct development	GO:0060066	3	0.044
regulation of lymphocyte proliferation	GO:0050670	117	0.044
ribose phosphate metabolic process	GO:0019693	291	0.044
myeloid cell differentiation	GO:0030099	233	0.044
bmp signaling pathway	GO:0030509	93	0.043
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.043
organic cyclic compound catabolic process	GO:1901361	295	0.043
alpha beta t cell differentiation	GO:0046632	69	0.043
cardiac muscle tissue development	GO:0048738	130	0.043
regulation of hormone levels	GO:0010817	211	0.043
cell junction organization	GO:0034330	77	0.043
single organism nuclear import	GO:1902593	95	0.043
regulation of endopeptidase activity	GO:0052548	89	0.042
carbohydrate derivative catabolic process	GO:1901136	231	0.042
oocyte development	GO:0048599	33	0.042
nucleoside triphosphate metabolic process	GO:0009141	230	0.042
regulation of t cell proliferation	GO:0042129	92	0.042
regulation of proteolysis	GO:0030162	164	0.042
regulation of epithelial cell proliferation	GO:0050678	141	0.042
cd4 positive alpha beta t cell activation	GO:0035710	45	0.042
lipid localization	GO:0010876	126	0.042
regulation of ras gtpase activity	GO:0032318	88	0.042
cd4 positive alpha beta t cell differentiation involved in immune response	GO:0002294	28	0.042
cellular response to hormone stimulus	GO:0032870	150	0.041
regulation of system process	GO:0044057	200	0.041
positive regulation of kinase activity	GO:0033674	155	0.041
purine containing compound metabolic process	GO:0072521	311	0.041
regulation of cellular response to stress	GO:0080135	159	0.041
regulation of rho protein signal transduction	GO:0035023	71	0.041
regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061178	31	0.040
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.040
compound eye development	GO:0048749	1	0.040	Fly
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.040
regulation of organ growth	GO:0046620	61	0.040
cation transmembrane transport	GO:0098655	266	0.040
defecation	GO:0030421	1	0.040
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.039
protein catabolic process	GO:0030163	221	0.039
mesenchyme development	GO:0060485	152	0.039
regulation of leukocyte proliferation	GO:0070663	121	0.039
cardiac muscle tissue morphogenesis	GO:0055008	44	0.039
negative regulation of nervous system development	GO:0051961	156	0.039
cellular response to cytokine stimulus	GO:0071345	189	0.039
establishment of mitochondrion localization	GO:0051654	4	0.039
jnk cascade	GO:0007254	72	0.039
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.039
sensory system development	GO:0048880	3	0.039
myotube differentiation	GO:0014902	105	0.039
positive regulation of cell death	GO:0010942	224	0.038
response to radiation	GO:0009314	165	0.038
stress activated protein kinase signaling cascade	GO:0031098	81	0.038
axis elongation	GO:0003401	30	0.038
keratinocyte differentiation	GO:0030216	48	0.038
purine nucleotide metabolic process	GO:0006163	302	0.038
cartilage development	GO:0051216	140	0.038
regulation of t cell activation	GO:0050863	170	0.038
mitotic cell cycle	GO:0000278	195	0.038
cellular response to amino acid stimulus	GO:0071230	29	0.038
positive regulation of transferase activity	GO:0051347	167	0.038
organ growth	GO:0035265	117	0.038
endodermal cell fate specification	GO:0001714	4	0.037
transmembrane transport	GO:0055085	412	0.037
regulation of peptide transport	GO:0090087	91	0.037
t cell differentiation in thymus	GO:0033077	77	0.037
regulation of anatomical structure size	GO:0090066	178	0.037	Fly
dephosphorylation	GO:0016311	129	0.037
exocrine system development	GO:0035272	45	0.037
cell substrate adhesion	GO:0031589	130	0.036
regulation of lymphocyte differentiation	GO:0045619	107	0.036
response to molecule of bacterial origin	GO:0002237	143	0.036
regulation of asymmetric cell division	GO:0009786	4	0.036
cilium assembly	GO:0042384	81	0.036	Mouse
glucose homeostasis	GO:0042593	128	0.036
detection of stimulus	GO:0051606	84	0.036
extracellular structure organization	GO:0043062	148	0.035
learning or memory	GO:0007611	148	0.035
regulation of fat cell differentiation	GO:0045598	81	0.035
urogenital system development	GO:0001655	261	0.035
positive regulation of cellular catabolic process	GO:0031331	148	0.035
adaptive immune response	GO:0002250	155	0.035
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.034
positive regulation of protein modification process	GO:0031401	299	0.034
positive regulation of cell projection organization	GO:0031346	95	0.034
negative regulation of growth	GO:0045926	99	0.034
purine ribonucleoside catabolic process	GO:0046130	205	0.034
hematopoietic progenitor cell differentiation	GO:0002244	143	0.034
ribonucleoside metabolic process	GO:0009119	245	0.034
organelle localization	GO:0051640	179	0.034
regulation of body fluid levels	GO:0050878	162	0.034	Mouse
ameboidal type cell migration	GO:0001667	128	0.034	Zebrafish
glycosyl compound metabolic process	GO:1901657	246	0.034
dendrite self avoidance	GO:0070593	2	0.034	Fly
establishment of monopolar cell polarity	GO:0061162	8	0.034
tissue migration	GO:0090130	68	0.034
adult locomotory behavior	GO:0008344	91	0.034
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.034
organophosphate catabolic process	GO:0046434	232	0.033
positive regulation of protein phosphorylation	GO:0001934	242	0.033
response to peptide	GO:1901652	136	0.033
regulation of mitotic cell cycle	GO:0007346	126	0.033
mitotic cell cycle process	GO:1903047	159	0.033
positive regulation of protein kinase activity	GO:0045860	144	0.033
response to amino acid	GO:0043200	37	0.033
purine ribonucleoside metabolic process	GO:0046128	241	0.033
hormone metabolic process	GO:0042445	86	0.033
epithelium migration	GO:0090132	63	0.033
glial cell differentiation	GO:0010001	131	0.033
regulation of stem cell proliferation	GO:0072091	78	0.033
leukocyte activation involved in immune response	GO:0002366	126	0.032
cellular ion homeostasis	GO:0006873	165	0.032
hormone secretion	GO:0046879	128	0.032
detection of abiotic stimulus	GO:0009582	60	0.032
limbic system development	GO:0021761	72	0.032
regulation of bmp signaling pathway	GO:0030510	60	0.032
regulation of actin filament based process	GO:0032970	99	0.032
regulation of leukocyte differentiation	GO:1902105	159	0.032
positive regulation of cell development	GO:0010720	237	0.032
detection of external stimulus	GO:0009581	61	0.031
lipid biosynthetic process	GO:0008610	179	0.031
cellular response to molecule of bacterial origin	GO:0071219	83	0.031
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.031
microtubule cytoskeleton organization	GO:0000226	157	0.031
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.031
interleukin 8 production	GO:0032637	4	0.031
positive regulation of apoptotic process	GO:0043065	217	0.031
sulfur compound metabolic process	GO:0006790	100	0.030
regulation of synaptic plasticity	GO:0048167	87	0.030
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.030
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.030
mesoderm formation	GO:0001707	62	0.030
cell cell junction organization	GO:0045216	72	0.030
protein localization to organelle	GO:0033365	185	0.030
cytokine production	GO:0001816	319	0.030
organic acid transport	GO:0015849	101	0.030
regulation of protein localization	GO:0032880	231	0.030	Mouse
intrinsic apoptotic signaling pathway	GO:0097193	132	0.030
ribonucleotide catabolic process	GO:0009261	208	0.030
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.030
cerebellum development	GO:0021549	77	0.030
apoptotic process involved in morphogenesis	GO:0060561	25	0.029
negative regulation of epithelial cell proliferation	GO:0050680	64	0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.029
neuroblast proliferation	GO:0007405	49	0.029
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.029
cell type specific apoptotic process	GO:0097285	268	0.029
negative regulation of cell cycle	GO:0045786	123	0.029
covalent chromatin modification	GO:0016569	163	0.029
regulation of peptidase activity	GO:0052547	96	0.029
negative regulation of phosphorus metabolic process	GO:0010563	184	0.029
neuronal action potential	GO:0019228	54	0.029
cochlea morphogenesis	GO:0090103	22	0.029
maintenance of location	GO:0051235	89	0.029
planar cell polarity pathway involved in axis elongation	GO:0003402	4	0.029
central nervous system neuron differentiation	GO:0021953	162	0.029
skin morphogenesis	GO:0043589	38	0.029
carbohydrate metabolic process	GO:0005975	230	0.029
kidney morphogenesis	GO:0060993	83	0.029
nucleotide catabolic process	GO:0009166	217	0.029
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.029
mesoderm morphogenesis	GO:0048332	64	0.029
negative regulation of t cell activation	GO:0050868	65	0.029
cytoplasmic transport	GO:0016482	234	0.028
activation of immune response	GO:0002253	138	0.028
lymphocyte mediated immunity	GO:0002449	139	0.028
positive regulation of hydrolase activity	GO:0051345	148	0.028
negative regulation of protein phosphorylation	GO:0001933	126	0.028
purine nucleoside catabolic process	GO:0006152	205	0.028
innate immune response	GO:0045087	157	0.028
microtubule based process	GO:0007017	236	0.028	Mouse
chromatin modification	GO:0016568	187	0.028
fatty acid metabolic process	GO:0006631	121	0.028
mesodermal cell migration	GO:0008078	4	0.028
regulation of apoptotic signaling pathway	GO:2001233	197	0.028
steroid metabolic process	GO:0008202	119	0.028
myeloid leukocyte differentiation	GO:0002573	119	0.027
regulation of cell cycle process	GO:0010564	160	0.027
fat cell differentiation	GO:0045444	160	0.027
negative regulation of cellular amine metabolic process	GO:0033239	1	0.027
epithelial cell morphogenesis	GO:0003382	41	0.027
gonad development	GO:0008406	141	0.027
regulation of nucleotide catabolic process	GO:0030811	122	0.027
homeostasis of number of cells	GO:0048872	210	0.027
regulation of protein serine threonine kinase activity	GO:0071900	157	0.027
anatomical structure homeostasis	GO:0060249	145	0.027
regulation of interleukin 8 production	GO:0032677	3	0.027
cardiac septum morphogenesis	GO:0060411	46	0.027
cellular metal ion homeostasis	GO:0006875	151	0.027
renal vesicle induction	GO:0072034	3	0.027
actin filament based movement	GO:0030048	23	0.027
retina development in camera type eye	GO:0060041	119	0.027
chromatin organization	GO:0006325	206	0.027
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.027	Mouse Fly
regulation of binding	GO:0051098	111	0.027
inorganic ion transmembrane transport	GO:0098660	234	0.026
leukocyte mediated immunity	GO:0002443	174	0.026
response to light stimulus	GO:0009416	135	0.026
cell maturation	GO:0048469	127	0.026
positive regulation of epithelial cell proliferation	GO:0050679	68	0.026
auditory receptor cell differentiation	GO:0042491	37	0.026
lymphocyte activation involved in immune response	GO:0002285	93	0.026
negative regulation of protein maturation	GO:1903318	79	0.026
nerve development	GO:0021675	67	0.026
protein modification by small protein conjugation or removal	GO:0070647	207	0.026
t helper cell differentiation	GO:0042093	28	0.026
regulation of protein transport	GO:0051223	163	0.026
lateral sprouting involved in lung morphogenesis	GO:0060490	2	0.026
regulation of protein import into nucleus	GO:0042306	52	0.025
nephron epithelium development	GO:0072009	92	0.025
nephric duct formation	GO:0072179	4	0.025
post anal tail morphogenesis	GO:0036342	23	0.025
mesonephric tubule development	GO:0072164	94	0.025
negative regulation of neuron differentiation	GO:0045665	101	0.025
cellular response to monosaccharide stimulus	GO:0071326	47	0.025
developmental cell growth	GO:0048588	84	0.025
regulation of protein targeting	GO:1903533	61	0.025
ovulation	GO:0030728	15	0.025
purine nucleotide catabolic process	GO:0006195	211	0.025
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.025
regulation of muscle tissue development	GO:1901861	97	0.025
regulation of intracellular transport	GO:0032386	159	0.025
regulation of vesicle mediated transport	GO:0060627	139	0.025
negative regulation of proteolysis	GO:0045861	74	0.025
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.025
organonitrogen compound catabolic process	GO:1901565	264	0.025
striated muscle cell development	GO:0055002	125	0.025
positive regulation of cell activation	GO:0050867	158	0.025
dna metabolic process	GO:0006259	303	0.025
establishment of epithelial cell polarity	GO:0090162	10	0.025
cellular modified amino acid metabolic process	GO:0006575	63	0.025
cellular protein complex assembly	GO:0043623	116	0.025
cardiac ventricle morphogenesis	GO:0003208	50	0.024
extracellular matrix organization	GO:0030198	147	0.024

Celsr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.063
nervous system disease	DOID:863	0.063
sensory system disease	DOID:0050155	0.050
cardiovascular system disease	DOID:1287	0.039

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