Mus musculus

11 known processes

Psenen

presenilin enhancer 2 homolog (C. elegans)

(Aliases: 1700023M09Rik,MGC102026)

Psenen biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
copper ion transportGO:0006825100.199
regulation of resting membrane potentialGO:006007530.167
modification dependent macromolecule catabolic processGO:00436321330.151
cellular protein catabolic processGO:00442571550.107
proteolysis involved in cellular protein catabolic processGO:00516031470.097
protein maturationGO:00516041760.091
Human
regulation of epidermal growth factor activated receptor activityGO:000717670.083
negative regulation of protein processingGO:0010955790.069
modification dependent protein catabolic processGO:00199411330.068
protein modification by small protein conjugationGO:00324461870.064
macromolecule catabolic processGO:00090572810.063
regulation of cellular amino acid metabolic processGO:000652150.061
choline transportGO:001587130.059
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.057
lateral inhibitionGO:004633110.056
protein catabolic processGO:00301632210.054
ubiquitin dependent protein catabolic processGO:00065111290.053
negative regulation of protein metabolic processGO:00512482820.050
negative regulation of cellular protein metabolic processGO:00322692470.049
negative regulation of protein modification processGO:00314001630.044
notch receptor processingGO:000722040.044
cellular macromolecule catabolic processGO:00442652060.043
transmembrane transportGO:00550854120.042
positive regulation of cell deathGO:00109422240.042
regulation of kinase activityGO:00435492490.041
cation transportGO:00068123990.041
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.038
ion transmembrane transportGO:00342203610.037
ribose phosphate metabolic processGO:00196932910.036
cellular amino acid metabolic processGO:00065201030.036
regulation of cellular catabolic processGO:00313292420.036
notch signaling pathwayGO:0007219710.036
Worm
protein processingGO:00164851630.036
Human
protein modification by small protein conjugation or removalGO:00706472070.036
regulation of protein processingGO:0070613960.035
regulation of apoptotic signaling pathwayGO:20012331970.035
regulation of proteolysisGO:00301621640.035
spermatogenesisGO:00072832840.035
negative regulation of molecular functionGO:00440922580.034
embryonic organ morphogenesisGO:00485622760.034
apoptotic signaling pathwayGO:00971903060.033
negative regulation of cellular amino acid metabolic processGO:004576300.033
mitochondrion organizationGO:00070051340.032
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.031
protein ubiquitinationGO:00165671710.031
regulation of protein maturationGO:1903317960.031
proteasomal protein catabolic processGO:0010498980.030
regulation of neuron differentiationGO:00456642810.029
microtubule based processGO:00070172360.029
negative regulation of epidermal growth factor activated receptor activityGO:000717530.028
beta amyloid metabolic processGO:0050435140.028
cation transmembrane transportGO:00986552660.028
cellular ketone metabolic processGO:0042180840.028
cellular protein complex assemblyGO:00436231160.027
regulation of cellular ketone metabolic processGO:0010565660.027
negative regulation of proteolysisGO:0045861740.027
negative regulation of protein tyrosine kinase activityGO:006109930.027
transition metal ion transportGO:0000041380.026
negative regulation of protein maturationGO:1903318790.026
regulation of cellular protein catabolic processGO:1903362610.026
inorganic ion transmembrane transportGO:00986602340.025
determination of left right symmetryGO:0007368800.025
organelle fissionGO:00482851700.025
positive regulation of apoptotic signaling pathwayGO:2001235950.025
endomembrane system organizationGO:00102561470.024
cellular divalent inorganic cation homeostasisGO:00725031270.024
positive regulation of proteolysisGO:0045862850.024
cellular amine metabolic processGO:0044106440.024
regulation of hydrolase activityGO:00513362460.023
negative regulation of cellular catabolic processGO:0031330470.023
regulation of cellular component biogenesisGO:00440871810.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
cytoplasmic transportGO:00164822340.022
divalent inorganic cation transportGO:00725111780.022
growth involved in heart morphogenesisGO:000324140.021
regulation of cellular amine metabolic processGO:0033238200.021
regulation of membrane potentialGO:00423911920.021
response to extracellular stimulusGO:00099911270.021
regulation of transferase activityGO:00513382630.021
negative regulation of cell developmentGO:00107211690.021
regulation of neurotransmitter levelsGO:0001505870.020
endoplasmic reticulum calcium ion homeostasisGO:0032469110.020
epithelial cell proliferationGO:00506731740.020
ossificationGO:00015032160.020
purine ribonucleotide metabolic processGO:00091502900.019
membrane lipid biosynthetic processGO:0046467320.019
inorganic cation transmembrane transportGO:00986622070.019
neuron deathGO:00709971540.019
Zebrafish
carbohydrate derivative catabolic processGO:19011362310.019
negative regulation of protein phosphorylationGO:00019331260.019
cation homeostasisGO:00550802120.019
neurotransmitter transportGO:0006836760.019
nuclear divisionGO:00002801580.019
release of cytochrome c from mitochondriaGO:0001836230.019
regulation of cell projection organizationGO:00313442060.019
interspecies interaction between organismsGO:0044419830.019
nucleoside triphosphate catabolic processGO:00091432050.019
extracellular structure organizationGO:00430621480.019
regulation of protein modification by small protein conjugation or removalGO:1903320570.019
nitrogen compound transportGO:00717052710.019
t cell activationGO:00421102890.019
negative regulation of cellular protein catabolic processGO:1903363220.018
regulation of protein catabolic processGO:00421761080.018
ras protein signal transductionGO:0007265770.018
amine metabolic processGO:0009308450.018
microtubule based movementGO:0007018840.018
protein localization to membraneGO:00726571080.018
regionalizationGO:00030023370.018
regulation of peptidase activityGO:0052547960.018
immune effector processGO:00022523210.018
male gamete generationGO:00482322850.018
negative regulation of kinase activityGO:0033673810.018
positive regulation of transferase activityGO:00513471670.018
regulation of secretionGO:00510462740.018
hematopoietic progenitor cell differentiationGO:00022441430.018
digestive tract developmentGO:00485651900.018
Worm
negative regulation of neuron differentiationGO:00456651010.018
autophagic vacuole fusionGO:000004610.017
organelle membrane fusionGO:009017410.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.017
cellular chemical homeostasisGO:00550822150.017
negative regulation of protein modification by small protein conjugation or removalGO:1903321200.017
organic hydroxy compound transportGO:0015850930.017
peptidyl amino acid modificationGO:00181933360.017
positive regulation of protein phosphorylationGO:00019342420.016
negative regulation of ligase activityGO:005135230.016
extrinsic apoptotic signaling pathwayGO:00971911260.016
regulation of cell migrationGO:00303342190.016
negative regulation of ubiquitin protein transferase activityGO:005144430.016
regulation of intracellular protein transportGO:0033157820.016
purine containing compound metabolic processGO:00725213110.016
cellular response to extracellular stimulusGO:0031668810.016
mapk cascadeGO:00001652810.016
regulation of establishment of protein localizationGO:00702011810.016
ribonucleoside metabolic processGO:00091192450.016
negative regulation of phosphorylationGO:00423261660.016
vesicle organizationGO:0016050600.016
autophagyGO:0006914450.016
carbohydrate homeostasisGO:00335001280.016
acidic amino acid transportGO:0015800160.016
regulation of organelle organizationGO:00330432890.015
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.015
cellular homeostasisGO:00197252400.015
regulation of cytoplasmic transportGO:19036491120.015
intracellular protein transportGO:00068862040.015
divalent metal ion transportGO:00708381720.015
negative regulation of phosphate metabolic processGO:00459361840.015
membrane organizationGO:00610242450.015
purine nucleoside metabolic processGO:00422782410.015
synaptic transmissionGO:00072683290.015
positive regulation of mapk cascadeGO:00434101700.015
regulation of ion transportGO:00432692150.015
regulation of protein localizationGO:00328802310.015
myotube differentiationGO:00149021050.015
regulation of protein kinase activityGO:00458592320.015
nucleotide metabolic processGO:00091173320.015
positive regulation of interleukin 8 productionGO:003275720.015
heart morphogenesisGO:00030071780.014
water soluble vitamin biosynthetic processGO:004236430.014
leukocyte differentiationGO:00025213420.014
respiratory tube developmentGO:00303231670.014
regulation of cell motilityGO:20001452360.014
positive regulation of protein kinase activityGO:00458601440.014
positive regulation of protein modification processGO:00314012990.014
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.014
regulation of protein serine threonine kinase activityGO:00719001570.014
autophagic vacuole assemblyGO:0000045130.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.014
cellular response to dna damage stimulusGO:00069742070.014
regulation of mapk cascadeGO:00434082480.014
regulation of vesicle mediated transportGO:00606271390.014
exocytosisGO:00068871210.014
organelle localizationGO:00516401790.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
negative regulation of phosphorus metabolic processGO:00105631840.014
negative regulation of cellular component organizationGO:00511291940.014
positive regulation of programmed cell deathGO:00430682180.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.013
positive regulation of cellular amine metabolic processGO:003324050.013
somitogenesisGO:0001756690.013
embryonic heart tube morphogenesisGO:0003143510.013
developmental maturationGO:00217001930.013
regulation of map kinase activityGO:00434051200.013
viral buddingGO:004675510.013
negative regulation of nervous system developmentGO:00519611560.013
regulation of proteasomal protein catabolic processGO:0061136460.013
purine nucleotide catabolic processGO:00061952110.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
cellular ion homeostasisGO:00068731650.013
single organism cell adhesionGO:00986021560.013
calcium ion homeostasisGO:00550741270.013
symbiosis encompassing mutualism through parasitismGO:0044403830.013
regulation of receptor recyclingGO:000191980.013
mitotic cell cycleGO:00002781950.013
nucleoside phosphate metabolic processGO:00067533380.013
posttranscriptional regulation of gene expressionGO:00106081550.013
purine nucleoside catabolic processGO:00061522050.013
ameboidal type cell migrationGO:00016671280.013
meiotic nuclear divisionGO:00071261150.013
somite developmentGO:0061053810.013
regulation of endopeptidase activityGO:0052548890.013
nucleobase containing small molecule metabolic processGO:00550863520.012
organic cyclic compound catabolic processGO:19013612950.012
meiotic cell cycleGO:00513211220.012
regulation of lymphocyte activationGO:00512492400.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
heterocycle catabolic processGO:00467002800.012
locomotory behaviorGO:00076261950.012
filopodium assemblyGO:0046847190.012
activation of mapkk activityGO:0000186150.012
blood circulationGO:00080151950.012
regulation of epithelial cell proliferationGO:00506781410.012
establishment of organelle localizationGO:00516561220.012
establishment of vesicle localizationGO:0051650810.012
regulation of secretion by cellGO:19035302490.012
embryonic limb morphogenesisGO:00303261260.012
smoothened signaling pathwayGO:00072241050.012
inflammatory responseGO:00069542440.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.012
negative regulation of transferase activityGO:0051348850.012
cell growthGO:00160491300.012
purine ribonucleotide catabolic processGO:00091542080.011
actin cytoskeleton organizationGO:00300362200.011
interleukin 8 productionGO:003263740.011
positive regulation of apoptotic processGO:00430652170.011
regulation of transmembrane transportGO:00347621280.011
nucleotide catabolic processGO:00091662170.011
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005960.011
regulation of neuron projection developmentGO:00109751690.011
negative regulation of erbb signaling pathwayGO:190118570.011
amino acid transportGO:0006865610.011
skeletal system developmentGO:00015013560.011
regulation of cell activationGO:00508652890.011
lipoprotein metabolic processGO:0042157430.011
glucose homeostasisGO:00425931280.011
striated muscle myosin thick filament assemblyGO:007168810.011
respiratory system developmentGO:00605411900.011
anatomical structure homeostasisGO:00602491450.011
response to oxidative stressGO:00069791230.011
negative regulation of cell cycleGO:00457861230.011
learning or memoryGO:00076111480.011
negative regulation of protein catabolic processGO:0042177360.011
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.011
muscle contractionGO:00069361010.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
regulation of protein transportGO:00512231630.011
response to nutrient levelsGO:00316671090.010
muscle tissue developmentGO:00605373080.010
metal ion homeostasisGO:00550651890.010
regulation of protein bindingGO:0043393600.010
limb developmentGO:00601731660.010
cellular response to cytokine stimulusGO:00713451890.010
circulatory system processGO:00030131970.010
cellular nitrogen compound catabolic processGO:00442702800.010
organonitrogen compound biosynthetic processGO:19015661920.010
cellular response to lipidGO:00713961450.010
positive regulation of kinase activityGO:00336741550.010
vesicle localizationGO:0051648860.010
virion assemblyGO:001906810.010
digestive system developmentGO:00551232000.010
Worm
limb morphogenesisGO:00351081490.010
response to starvationGO:0042594650.010
neurotransmitter secretionGO:0007269620.010
epithelial tube morphogenesisGO:00605623030.010

Psenen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.102
Human
nervous system diseaseDOID:86300.102
central nervous system diseaseDOID:33100.102
muscle tissue diseaseDOID:6600.057
myopathyDOID:42300.057
musculoskeletal system diseaseDOID:1700.057
muscular diseaseDOID:008000000.057
cardiovascular system diseaseDOID:128700.048
intrinsic cardiomyopathyDOID:006003600.048
dilated cardiomyopathyDOID:1293000.048
heart diseaseDOID:11400.048
cardiomyopathyDOID:005070000.048
neurodegenerative diseaseDOID:128900.041
skin diseaseDOID:3700.030
Human
integumentary system diseaseDOID:1600.030
Human
disease of mental healthDOID:15000.024
cognitive disorderDOID:156100.024
alzheimer s diseaseDOID:1065200.018
tauopathyDOID:68000.018
dementiaDOID:130700.018
immune system diseaseDOID:291400.017
disease of metabolismDOID:001466700.015
brain diseaseDOID:93600.013
anemiaDOID:235500.010
hematopoietic system diseaseDOID:7400.010
bone marrow diseaseDOID:496100.010
aplastic anemiaDOID:1244900.010