| microtubule severing | GO:0051013 | 5 | 0.488 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.128 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.118 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.118 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.117 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.117 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.109 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.107 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.105 | |
| protein catabolic process | GO:0030163 | 221 | 0.105 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.085 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.084 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.084 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.079 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.079 | |
| dna recombination | GO:0006310 | 92 | 0.077 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.071 | |
| dna repair | GO:0006281 | 107 | 0.069 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.060 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.059 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.055 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.053 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.051 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.047 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.047 | |
| dna metabolic process | GO:0006259 | 303 | 0.046 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.046 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.045 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.045 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.045 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.044 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.044 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.044 | |
| protein ubiquitination | GO:0016567 | 171 | 0.043 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.043 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.042 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.042 | |
| intracellular protein transport | GO:0006886 | 204 | 0.042 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.041 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.041 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.040 | |
| organelle assembly | GO:0070925 | 177 | 0.040 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.039 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.038 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.038 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.038 | |
| synaptic transmission | GO:0007268 | 329 | 0.037 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.037 | |
| regulation of protein localization | GO:0032880 | 231 | 0.037 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.036 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.034 | |
| histone h2a ubiquitination | GO:0033522 | 3 | 0.034 | |
| protein localization to organelle | GO:0033365 | 185 | 0.033 | |
| double strand break repair | GO:0006302 | 48 | 0.033 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.033 | |
| cell division | GO:0051301 | 120 | 0.033 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.033 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.032 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.031 | |
| methylation | GO:0032259 | 134 | 0.031 | |
| macromolecule methylation | GO:0043414 | 120 | 0.030 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.030 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.029 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.029 | |
| spermatid development | GO:0007286 | 108 | 0.029 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.028 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.028 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.028 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.027 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.027 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.027 | |
| amine metabolic process | GO:0009308 | 45 | 0.026 | |
| cell adhesion | GO:0007155 | 329 | 0.026 | |
| organelle fission | GO:0048285 | 170 | 0.026 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.026 | |
| microtubule based process | GO:0007017 | 236 | 0.026 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.026 | |
| immune effector process | GO:0002252 | 321 | 0.025 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.025 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.025 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.025 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.025 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.025 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.025 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.024 | |
| membrane organization | GO:0061024 | 245 | 0.024 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.024 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.024 | |
| protein targeting | GO:0006605 | 143 | 0.024 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.024 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.023 | |
| response to radiation | GO:0009314 | 165 | 0.023 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.023 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.023 | |
| transmembrane transport | GO:0055085 | 412 | 0.023 | |
| exocytosis | GO:0006887 | 121 | 0.022 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.022 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.022 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.022 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.022 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.022 | |
| t cell activation | GO:0042110 | 289 | 0.021 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.021 | |
| adult behavior | GO:0030534 | 135 | 0.021 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.021 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.020 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.020 | |
| protein import into nucleus | GO:0006606 | 95 | 0.020 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.020 | |
| positive regulation of nfat protein import into nucleus | GO:0051533 | 1 | 0.020 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.020 | |
| multicellular organism growth | GO:0035264 | 161 | 0.020 | |
| regulation of cell activation | GO:0050865 | 289 | 0.020 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.020 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.020 | |
| organelle localization | GO:0051640 | 179 | 0.019 | |
| hematopoietic stem cell migration | GO:0035701 | 1 | 0.019 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.019 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.019 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.019 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.019 | |
| response to insulin | GO:0032868 | 100 | 0.019 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.019 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.019 | |
| neuron death | GO:0070997 | 154 | 0.019 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.018 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.018 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.018 | |
| defense response to other organism | GO:0098542 | 197 | 0.018 | |
| protein import | GO:0017038 | 101 | 0.018 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.018 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.018 | |
| nuclear transport | GO:0051169 | 139 | 0.018 | |
| recombinational repair | GO:0000725 | 21 | 0.017 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.017 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 43 | 0.017 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.017 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.017 | |
| b cell activation | GO:0042113 | 161 | 0.017 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.017 | |
| mapk cascade | GO:0000165 | 281 | 0.017 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.017 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.017 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.017 | |
| adaptive immune response | GO:0002250 | 155 | 0.017 | |
| nuclear division | GO:0000280 | 158 | 0.017 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.017 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.016 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.016 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.016 | |
| microtubule depolymerization | GO:0007019 | 15 | 0.016 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.016 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.016 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.016 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.016 | |
| amide transport | GO:0042886 | 138 | 0.016 | |
| vesicle organization | GO:0016050 | 60 | 0.016 | |
| regulation of protein transport | GO:0051223 | 163 | 0.016 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.016 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.016 | |
| histone modification | GO:0016570 | 159 | 0.016 | |
| centrosome cycle | GO:0007098 | 23 | 0.016 | |
| protein refolding | GO:0042026 | 1 | 0.016 | |
| regulation of microtubule based process | GO:0032886 | 52 | 0.016 | |
| spindle assembly involved in meiosis | GO:0090306 | 4 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.015 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.015 | |
| tube closure | GO:0060606 | 91 | 0.015 | |
| positive regulation of cell adhesion | GO:0045785 | 80 | 0.015 | |
| single organism nuclear import | GO:1902593 | 95 | 0.015 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.015 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.015 | |
| cation transport | GO:0006812 | 399 | 0.015 | |
| gtp metabolic process | GO:0046039 | 144 | 0.015 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.015 | |
| response to light stimulus | GO:0009416 | 135 | 0.015 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.015 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.015 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.015 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.015 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.015 | |
| chromatin modification | GO:0016568 | 187 | 0.015 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.015 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.015 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.015 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.015 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.014 | |
| cell growth | GO:0016049 | 130 | 0.014 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.014 | |
| genetic imprinting | GO:0071514 | 27 | 0.014 | |
| regionalization | GO:0003002 | 337 | 0.014 | |
| spermatid differentiation | GO:0048515 | 115 | 0.014 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.014 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.014 | |
| t cell differentiation | GO:0030217 | 174 | 0.014 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.014 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.014 | |
| endomembrane system organization | GO:0010256 | 147 | 0.014 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.013 | |
| protein lipidation | GO:0006497 | 28 | 0.013 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.013 | |
| regulation of secretion | GO:0051046 | 274 | 0.013 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.013 | |
| locomotory behavior | GO:0007626 | 195 | 0.013 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.013 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.013 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.013 | |
| stem cell development | GO:0048864 | 219 | 0.013 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.013 | |
| response to uv | GO:0009411 | 44 | 0.013 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.013 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.013 | |
| response to growth factor | GO:0070848 | 198 | 0.013 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.013 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.013 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.012 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.012 | |
| neural tube development | GO:0021915 | 160 | 0.012 | |
| protein acylation | GO:0043543 | 64 | 0.012 | |
| neural tube closure | GO:0001843 | 90 | 0.012 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.012 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.012 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.012 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.012 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.012 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.012 | |
| blastocyst development | GO:0001824 | 80 | 0.012 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.012 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.012 | |
| rna processing | GO:0006396 | 105 | 0.012 | Human |
| establishment of vesicle localization | GO:0051650 | 81 | 0.012 | |
| chromatin organization | GO:0006325 | 206 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.012 | |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 46 | 0.012 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.012 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.012 | |
| cytokine production | GO:0001816 | 319 | 0.012 | |
| sperm motility | GO:0030317 | 47 | 0.011 | |
| dna dependent dna replication | GO:0006261 | 24 | 0.011 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 37 | 0.011 | |
| tube formation | GO:0035148 | 140 | 0.011 | |
| spermatogenesis | GO:0007283 | 284 | 0.011 | |
| stem cell maintenance | GO:0019827 | 130 | 0.011 | |
| centrosome duplication | GO:0051298 | 16 | 0.011 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.011 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.011 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.011 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.011 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.011 | |
| secretory granule organization | GO:0033363 | 20 | 0.011 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.011 | |
| regulation of ion transport | GO:0043269 | 215 | 0.011 | |
| positive regulation of homeostatic process | GO:0032846 | 64 | 0.011 | |
| nuclear import | GO:0051170 | 95 | 0.011 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.011 | |
| negative regulation of insulin receptor signaling pathway | GO:0046627 | 14 | 0.011 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.011 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.011 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.010 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.010 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.010 | |
| chemotaxis | GO:0006935 | 247 | 0.010 | |
| gland development | GO:0048732 | 330 | 0.010 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.010 | |
| synapse organization | GO:0050808 | 125 | 0.010 | |
| regulation of histone modification | GO:0031056 | 56 | 0.010 | |
| smoothened signaling pathway | GO:0007224 | 105 | 0.010 | |
| muscle tissue development | GO:0060537 | 308 | 0.010 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.010 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.010 | |
| regulation of protein stability | GO:0031647 | 52 | 0.010 | |
| positive regulation of axon extension | GO:0045773 | 20 | 0.010 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.010 | |
