IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Slc22a8

solute carrier family 22 (organic anion transporter), member 8

(Aliases: Roct,Oat3)

Ensembl: ENSMUSG00000063796
Entrez: 19879
UniProtKB: O88909

Process Predictions
Disease Predictions

Slc22a8 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
amino acid transmembrane transport	GO:0003333	37	0.949	Mouse
anion transmembrane transport	GO:0098656	71	0.856	Mouse
organic anion transport	GO:0015711	137	0.750	Mouse Rat
transmembrane transport	GO:0055085	412	0.688	Mouse Rat
synaptic transmission	GO:0007268	329	0.637	Mouse
amino acid transport	GO:0006865	61	0.631	Mouse Rat
ion transmembrane transport	GO:0034220	361	0.627	Mouse Rat
organic acid transport	GO:0015849	101	0.570	Mouse Rat
carboxylic acid transport	GO:0046942	100	0.492	Mouse Rat
anion transport	GO:0006820	177	0.471	Mouse Rat
inorganic ion transmembrane transport	GO:0098660	234	0.418
nitrogen compound transport	GO:0071705	271	0.407	Mouse Rat
urate transport	GO:0015747	1	0.339	Mouse
l amino acid transport	GO:0015807	32	0.335
organic hydroxy compound transport	GO:0015850	93	0.260	Mouse
organic hydroxy compound metabolic process	GO:1901615	203	0.250	Mouse
cation transport	GO:0006812	399	0.246	Mouse Rat
neuron neuron synaptic transmission	GO:0007270	69	0.221
carnitine metabolic process	GO:0009437	7	0.219	Mouse
sensory perception of light stimulus	GO:0050953	54	0.184
visual perception	GO:0007601	52	0.183
neurotransmitter transport	GO:0006836	76	0.182	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.164
regulation of peptide transport	GO:0090087	91	0.160
monocarboxylic acid metabolic process	GO:0032787	191	0.151	Mouse
modified amino acid transport	GO:0072337	5	0.149	Mouse Rat
amino acid betaine transport	GO:0015838	3	0.147	Mouse
renal system process	GO:0003014	48	0.144	Mouse
nucleoside phosphate metabolic process	GO:0006753	338	0.144
amine metabolic process	GO:0009308	45	0.143
response to organic cyclic compound	GO:0014070	198	0.140	Rat
cation homeostasis	GO:0055080	212	0.134
cell adhesion	GO:0007155	329	0.124
cellular amine metabolic process	GO:0044106	44	0.114
conditioned taste aversion	GO:0001661	4	0.109
carnitine transmembrane transport	GO:1902603	3	0.107	Mouse
action potential	GO:0001508	78	0.103
inorganic anion transport	GO:0015698	43	0.103
cation transmembrane transport	GO:0098655	266	0.102	Mouse Rat
regulation of cellular amine metabolic process	GO:0033238	20	0.100
transmission of nerve impulse	GO:0019226	76	0.095
neuronal action potential	GO:0019228	54	0.095
monoamine transport	GO:0015844	33	0.095	Mouse
response to light stimulus	GO:0009416	135	0.093
renal system development	GO:0072001	225	0.092
renal sodium ion transport	GO:0003096	2	0.091
adult behavior	GO:0030534	135	0.090
neutral amino acid transport	GO:0015804	13	0.087
response to nutrient levels	GO:0031667	109	0.087	Mouse
locomotory behavior	GO:0007626	195	0.079	Mouse
succinate transport	GO:0015744	1	0.079
cognition	GO:0050890	149	0.079
regulation of neurotransmitter levels	GO:0001505	87	0.077	Mouse
regulation of hormone levels	GO:0010817	211	0.076
inorganic cation transmembrane transport	GO:0098662	207	0.075
kidney development	GO:0001822	213	0.074
forebrain development	GO:0030900	302	0.072
amide transport	GO:0042886	138	0.072	Rat
regulation of ion transmembrane transporter activity	GO:0032412	54	0.071
c4 dicarboxylate transport	GO:0015740	3	0.070
response to radiation	GO:0009314	165	0.070
purine ribonucleotide metabolic process	GO:0009150	290	0.068
purine nucleotide metabolic process	GO:0006163	302	0.067
cellular chemical homeostasis	GO:0055082	215	0.066
regulation of g protein activated inward rectifier potassium channel activity	GO:1900128	1	0.065
organonitrogen compound biosynthetic process	GO:1901566	192	0.064
g protein coupled receptor signaling pathway	GO:0007186	243	0.063
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.061
regulation of inward rectifier potassium channel activity	GO:1901979	1	0.060
insulin secretion	GO:0030073	89	0.059
developmental maturation	GO:0021700	193	0.058
adult locomotory behavior	GO:0008344	91	0.057
histamine uptake	GO:0051615	1	0.057	Mouse
multicellular organism growth	GO:0035264	161	0.056
monocarboxylic acid transport	GO:0015718	44	0.056	Mouse
positive regulation of cellular catabolic process	GO:0031331	148	0.056
cellular homeostasis	GO:0019725	240	0.056
regulation of transferase activity	GO:0051338	263	0.056
regulation of cell activation	GO:0050865	289	0.056
regulation of membrane potential	GO:0042391	192	0.054
peptide hormone secretion	GO:0030072	109	0.053
dicarboxylic acid transport	GO:0006835	29	0.053
sodium ion transport	GO:0006814	73	0.053
regulation of neuronal synaptic plasticity	GO:0048168	30	0.052
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.052
inorganic anion transmembrane transport	GO:0098661	29	0.052
peptide secretion	GO:0002790	114	0.052
carnitine transport	GO:0015879	3	0.052	Mouse
neurotransmitter uptake	GO:0001504	14	0.051	Mouse
phenol containing compound metabolic process	GO:0018958	60	0.049
bone remodeling	GO:0046849	53	0.049
regulation of cellular ketone metabolic process	GO:0010565	66	0.049
divalent inorganic cation transport	GO:0072511	178	0.049
ossification	GO:0001503	216	0.048
regulation of synaptic plasticity	GO:0048167	87	0.047
positive regulation of cyclic nucleotide metabolic process	GO:0030801	24	0.046
regulation of heart rate	GO:0002027	36	0.045
positive regulation of protein phosphorylation	GO:0001934	242	0.044
nucleoside phosphate biosynthetic process	GO:1901293	79	0.044
regulation of ion transport	GO:0043269	215	0.044
ensheathment of neurons	GO:0007272	76	0.043
metal ion homeostasis	GO:0055065	189	0.043
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.043
cellular modified amino acid metabolic process	GO:0006575	63	0.042
catecholamine transport	GO:0051937	21	0.042
intracellular protein transport	GO:0006886	204	0.042
divalent inorganic cation homeostasis	GO:0072507	138	0.042
gliogenesis	GO:0042063	141	0.041
sensory perception	GO:0007600	245	0.041
monosaccharide metabolic process	GO:0005996	106	0.040
membrane organization	GO:0061024	245	0.040
regulation of protein serine threonine kinase activity	GO:0071900	157	0.040
operant conditioning	GO:0035106	2	0.040
regulation of mapk cascade	GO:0043408	248	0.040
regulation of kinase activity	GO:0043549	249	0.040
g protein coupled receptor internalization	GO:0002031	3	0.039
glycosyl compound metabolic process	GO:1901657	246	0.039
ribonucleotide metabolic process	GO:0009259	291	0.039
toxin transport	GO:1901998	38	0.039
regulation of cellular amino acid metabolic process	GO:0006521	5	0.038
mapk cascade	GO:0000165	281	0.038
negative regulation of molecular function	GO:0044092	258	0.038
cellular response to growth factor stimulus	GO:0071363	197	0.038
learning or memory	GO:0007611	148	0.037
nuclear transport	GO:0051169	139	0.037
hydrogen ion transmembrane transport	GO:1902600	25	0.037
body fluid secretion	GO:0007589	53	0.037
ribose phosphate metabolic process	GO:0019693	291	0.037
glial cell differentiation	GO:0010001	131	0.037
positive regulation of protein modification process	GO:0031401	299	0.036
sulfur compound transport	GO:0072348	9	0.036	Rat
regulation of peptide secretion	GO:0002791	77	0.036
immune effector process	GO:0002252	321	0.036
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.035
histamine induced gastric acid secretion	GO:0001697	1	0.035
positive regulation of transferase activity	GO:0051347	167	0.035
peptide transport	GO:0015833	133	0.035	Rat
glial cell development	GO:0021782	54	0.035
chloride transmembrane transport	GO:1902476	24	0.035
skeletal system development	GO:0001501	356	0.035
cytoplasmic transport	GO:0016482	234	0.035
negative regulation of serotonin secretion	GO:0014063	2	0.035
myelination	GO:0042552	74	0.035
digestive tract development	GO:0048565	190	0.034
sodium ion transmembrane transport	GO:0035725	49	0.034
regulation of secretion	GO:0051046	274	0.034
heart morphogenesis	GO:0003007	178	0.034
negative regulation of phosphorus metabolic process	GO:0010563	184	0.033
l glutamate uptake involved in synaptic transmission	GO:0051935	3	0.033
carbohydrate homeostasis	GO:0033500	128	0.033
positive regulation of kinase activity	GO:0033674	155	0.033
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.033
carbohydrate derivative biosynthetic process	GO:1901137	183	0.033
regulation of neuron death	GO:1901214	134	0.033
multicellular organismal signaling	GO:0035637	91	0.033
nucleotide metabolic process	GO:0009117	332	0.033
blood circulation	GO:0008015	195	0.032
response to extracellular stimulus	GO:0009991	127	0.031	Mouse
regulation of neuron apoptotic process	GO:0043523	122	0.031
nucleobase containing small molecule metabolic process	GO:0055086	352	0.031
potassium ion import	GO:0010107	1	0.031
response to organonitrogen compound	GO:0010243	246	0.031	Rat
glycine transport	GO:0015816	4	0.030
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.030
l alpha amino acid transmembrane transport	GO:1902475	23	0.030
chloride transport	GO:0006821	32	0.030
multicellular organismal homeostasis	GO:0048871	164	0.030
regulation of cytoskeleton organization	GO:0051493	122	0.030
glucose homeostasis	GO:0042593	128	0.029
positive regulation of heart rate by epinephrine norepinephrine	GO:0001996	4	0.029
learning	GO:0007612	98	0.029
angiogenesis	GO:0001525	201	0.029
memory	GO:0007613	58	0.029
regulation of blood pressure	GO:0008217	93	0.029
potassium ion homeostasis	GO:0055075	4	0.029
cellular ketone metabolic process	GO:0042180	84	0.029
regulation of system process	GO:0044057	200	0.029
midgut development	GO:0007494	4	0.029
nucleoside triphosphate metabolic process	GO:0009141	230	0.028
regulation of actin filament based process	GO:0032970	99	0.028
muscle tissue development	GO:0060537	308	0.028
regulation of cell adhesion	GO:0030155	154	0.028
regulation of transporter activity	GO:0032409	57	0.027
heterocycle catabolic process	GO:0046700	280	0.027
purine containing compound metabolic process	GO:0072521	311	0.027
cellular calcium ion homeostasis	GO:0006874	119	0.027
amino acid import into cell	GO:1902837	4	0.027
habituation	GO:0046959	3	0.027
cellular lipid metabolic process	GO:0044255	323	0.027
hormone secretion	GO:0046879	128	0.027
hormone metabolic process	GO:0042445	86	0.026
organic cyclic compound catabolic process	GO:1901361	295	0.026
axon ensheathment	GO:0008366	76	0.026
smooth muscle contraction	GO:0006939	44	0.026
positive regulation of the force of heart contraction by epinephrine norepinephrine	GO:0001997	3	0.026
response to growth factor	GO:0070848	198	0.026
protein import into nucleus	GO:0006606	95	0.026
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.026
negative regulation of neuron death	GO:1901215	98	0.026
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
sensory perception of mechanical stimulus	GO:0050954	107	0.026
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.026
multicellular organismal response to stress	GO:0033555	62	0.025
regulation of protein kinase activity	GO:0045859	232	0.025
urogenital system development	GO:0001655	261	0.025
histamine transport	GO:0051608	2	0.025	Mouse
regulation of response to wounding	GO:1903034	189	0.025
response to oxidative stress	GO:0006979	123	0.025
activation of adenylate cyclase activity	GO:0007190	4	0.025
regulation of hormone secretion	GO:0046883	88	0.025
regulation of circadian sleep wake cycle	GO:0042749	3	0.025
central nervous system neuron differentiation	GO:0021953	162	0.025
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.025
muscle contraction	GO:0006936	101	0.025
regulation of resting membrane potential	GO:0060075	3	0.025
heart contraction	GO:0060047	93	0.024
nucleoside phosphate catabolic process	GO:1901292	222	0.024
regulation of peptide hormone secretion	GO:0090276	75	0.024
gtp catabolic process	GO:0006184	143	0.024
actin filament organization	GO:0007015	113	0.024
organ growth	GO:0035265	117	0.024
establishment of protein localization to organelle	GO:0072594	118	0.024
ras protein signal transduction	GO:0007265	77	0.024
regulation of gtp catabolic process	GO:0033124	113	0.024
negative regulation of defense response	GO:0031348	77	0.024
regulation of anatomical structure size	GO:0090066	178	0.024
amino acid betaine metabolic process	GO:0006577	7	0.023	Mouse
dopamine transport	GO:0015872	15	0.023
actin cytoskeleton organization	GO:0030036	220	0.023
regulation of potassium ion transmembrane transporter activity	GO:1901016	7	0.023
regulation of action potential	GO:0098900	4	0.023
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.023
organophosphate biosynthetic process	GO:0090407	122	0.023
organophosphate catabolic process	GO:0046434	232	0.023
oxidation reduction process	GO:0055114	342	0.023
metanephric loop of henle development	GO:0072236	4	0.023
inflammatory response	GO:0006954	244	0.023
regulation of transmembrane transport	GO:0034762	128	0.023
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.023
social behavior	GO:0035176	21	0.023
organonitrogen compound catabolic process	GO:1901565	264	0.023
regulation of protein localization	GO:0032880	231	0.023
ribonucleotide biosynthetic process	GO:0009260	59	0.022
glycerolipid metabolic process	GO:0046486	122	0.022
negative regulation of inflammatory response	GO:0050728	61	0.022
protein targeting	GO:0006605	143	0.022
gastrin induced gastric acid secretion	GO:0001698	1	0.022
regulation of map kinase activity	GO:0043405	120	0.022
purine ribonucleotide biosynthetic process	GO:0009152	59	0.022
negative regulation of phosphorylation	GO:0042326	166	0.022
tissue remodeling	GO:0048771	102	0.022
monosaccharide transport	GO:0015749	58	0.022
regulation of ph	GO:0006885	26	0.022
circulatory system process	GO:0003013	197	0.022
sensory perception of sound	GO:0007605	97	0.022
succinate transmembrane transport	GO:0071422	1	0.022
nucleotide catabolic process	GO:0009166	217	0.022
nucleoside triphosphate catabolic process	GO:0009143	205	0.022
positive regulation of cellular amine metabolic process	GO:0033240	5	0.022
l glutamate import into cell	GO:1990123	3	0.022
regulation of hydrolase activity	GO:0051336	246	0.022
negative regulation of response to wounding	GO:1903035	77	0.021
protein localization to organelle	GO:0033365	185	0.021
nucleocytoplasmic transport	GO:0006913	139	0.021
camera type eye development	GO:0043010	266	0.021
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.021
monovalent inorganic cation homeostasis	GO:0055067	33	0.021
positive regulation of cell motility	GO:2000147	116	0.021
cellular ion homeostasis	GO:0006873	165	0.021
regulation of nucleotide metabolic process	GO:0006140	169	0.021
cellular potassium ion transport	GO:0071804	43	0.021
cerebellum morphogenesis	GO:0021587	42	0.021
response to ammonium ion	GO:0060359	21	0.021
regulation of muscle contraction	GO:0006937	49	0.021
neuron death	GO:0070997	154	0.021
positive regulation of nucleotide metabolic process	GO:0045981	114	0.021
ribonucleoside catabolic process	GO:0042454	206	0.021
cellular protein complex assembly	GO:0043623	116	0.021
regulation of cell projection organization	GO:0031344	206	0.021
single organism cell adhesion	GO:0098602	156	0.021
regulation of purine nucleotide metabolic process	GO:1900542	169	0.021
positive regulation of cell adhesion	GO:0045785	80	0.020
positive regulation of catecholamine secretion	GO:0033605	2	0.020
regulation of cell motility	GO:2000145	236	0.020
skeletal muscle organ development	GO:0060538	163	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
negative regulation of intracellular signal transduction	GO:1902532	167	0.020
carboxylic acid biosynthetic process	GO:0046394	86	0.020
regulation of cellular component biogenesis	GO:0044087	181	0.020
glycosyl compound catabolic process	GO:1901658	206	0.020
epithelial cell development	GO:0002064	159	0.020
milk ejection	GO:0060156	1	0.020
divalent metal ion transport	GO:0070838	172	0.020
exocytosis	GO:0006887	121	0.020
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.020
cell cell adhesion	GO:0098609	41	0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.020
amino acid uptake involved in synaptic transmission	GO:0051933	3	0.020
sulfur compound metabolic process	GO:0006790	100	0.020
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.020
catecholamine metabolic process	GO:0006584	30	0.019
purine nucleoside catabolic process	GO:0006152	205	0.019
gland development	GO:0048732	330	0.019
synapse organization	GO:0050808	125	0.019
neurotransmitter secretion	GO:0007269	62	0.019
cyclic purine nucleotide metabolic process	GO:0052652	43	0.019
carbohydrate transport	GO:0008643	62	0.019
acetylcholine transport	GO:0015870	2	0.019
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.019
regulation of purine nucleotide biosynthetic process	GO:1900371	34	0.019
detection of stimulus	GO:0051606	84	0.019
positive regulation of mapk cascade	GO:0043410	170	0.019
protein oligomerization	GO:0051259	67	0.019
second messenger mediated signaling	GO:0019932	73	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
heart process	GO:0003015	94	0.019
peptidyl amino acid modification	GO:0018193	336	0.019
purine nucleotide biosynthetic process	GO:0006164	65	0.019
regulation of ion transmembrane transport	GO:0034765	119	0.019
vascular process in circulatory system	GO:0003018	62	0.019
positive regulation of protein transport	GO:0051222	93	0.018
digestive tract morphogenesis	GO:0048546	147	0.018
cyclic nucleotide metabolic process	GO:0009187	59	0.018
regulation of serotonin secretion	GO:0014062	3	0.018
cellular carbohydrate metabolic process	GO:0044262	119	0.018
positive regulation of map kinase activity	GO:0043406	84	0.018
anatomical structure homeostasis	GO:0060249	145	0.018
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	3	0.018
regulation of multi organism process	GO:0043900	111	0.018
acetylcholine secretion neurotransmission	GO:0014055	2	0.018
positive regulation of glycolytic process	GO:0045821	4	0.018
response to acid chemical	GO:0001101	111	0.018	Rat
olfactory learning	GO:0008355	2	0.018
regulation of nucleoside metabolic process	GO:0009118	130	0.018
aromatic compound catabolic process	GO:0019439	286	0.018
biomineral tissue development	GO:0031214	64	0.018
single organism nuclear import	GO:1902593	95	0.018
protein localization to nucleus	GO:0034504	121	0.018
fatty acid metabolic process	GO:0006631	121	0.018
regulation of cell substrate adhesion	GO:0010810	73	0.017
positive regulation of growth	GO:0045927	104	0.017
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.017
regulation of long term neuronal synaptic plasticity	GO:0048169	19	0.017
dopamine metabolic process	GO:0042417	23	0.017
regulation of protein transport	GO:0051223	163	0.017
regulation of cell migration	GO:0030334	219	0.017
potassium ion transmembrane transport	GO:0071805	43	0.017
protein catabolic process	GO:0030163	221	0.017
camp mediated signaling	GO:0019933	15	0.017
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.017
cellular amino acid catabolic process	GO:0009063	25	0.017
organic acid biosynthetic process	GO:0016053	86	0.017
positive regulation of secretion by cell	GO:1903532	114	0.017
nucleoside metabolic process	GO:0009116	246	0.017
leukocyte differentiation	GO:0002521	342	0.017
regulation of organelle organization	GO:0033043	289	0.017
endocytosis	GO:0006897	168	0.017
adult walking behavior	GO:0007628	41	0.017
sensitization	GO:0046960	2	0.016
cellular response to temperature stimulus	GO:0071502	2	0.016
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.016
smoothened signaling pathway	GO:0007224	105	0.016
associative learning	GO:0008306	61	0.016
anatomical structure maturation	GO:0071695	49	0.016
cell type specific apoptotic process	GO:0097285	268	0.016
striated muscle tissue development	GO:0014706	293	0.016
placenta development	GO:0001890	140	0.016
purine ribonucleotide catabolic process	GO:0009154	208	0.016
intraspecies interaction between organisms	GO:0051703	21	0.016
visual learning	GO:0008542	44	0.016
lymphocyte mediated immunity	GO:0002449	139	0.016
regulation of body fluid levels	GO:0050878	162	0.016
cellular response to hexose stimulus	GO:0071331	47	0.016
guanosine containing compound metabolic process	GO:1901068	144	0.016
visual behavior	GO:0007632	45	0.016
av node cell to bundle of his cell communication	GO:0086067	2	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.016
positive regulation of cell substrate adhesion	GO:0010811	47	0.016
positive regulation of protein kinase activity	GO:0045860	144	0.016
peptidyl tyrosine phosphorylation	GO:0018108	143	0.015
purine containing compound catabolic process	GO:0072523	213	0.015
positive regulation of hydrolase activity	GO:0051345	148	0.015
muscle system process	GO:0003012	141	0.015
neuron apoptotic process	GO:0051402	142	0.015
regulation of heart contraction	GO:0008016	77	0.015
oligodendrocyte development	GO:0014003	20	0.015
positive regulation of gtp catabolic process	GO:0033126	85	0.015
regulation of secretion by cell	GO:1903530	249	0.015
hindbrain development	GO:0030902	128	0.015
positive regulation of secretion	GO:0051047	130	0.015
regulation of cellular response to stress	GO:0080135	159	0.015
purine ribonucleoside catabolic process	GO:0046130	205	0.015
positive regulation of dopamine secretion	GO:0033603	2	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.015
regulation of lymphocyte mediated immunity	GO:0002706	84	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015
norepinephrine transport	GO:0015874	2	0.015
establishment of organelle localization	GO:0051656	122	0.015
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.015
regulation of renin secretion into blood stream	GO:1900133	4	0.015
organic hydroxy compound catabolic process	GO:1901616	25	0.015
negative regulation of cell proliferation	GO:0008285	296	0.015
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.015
calcium ion homeostasis	GO:0055074	127	0.015
cerebellum development	GO:0021549	77	0.015
positive regulation of gtpase activity	GO:0043547	85	0.015
cyclic nucleotide biosynthetic process	GO:0009190	44	0.014
ventricular cardiac muscle cell action potential	GO:0086005	4	0.014
small gtpase mediated signal transduction	GO:0007264	97	0.014
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.014
purine ribonucleoside metabolic process	GO:0046128	241	0.014
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.014
detection of stimulus involved in sensory perception	GO:0050906	44	0.014
telencephalon development	GO:0021537	186	0.014
negative regulation of smooth muscle cell migration	GO:0014912	2	0.014
stem cell differentiation	GO:0048863	268	0.014
cellular response to carbohydrate stimulus	GO:0071322	50	0.014
positive regulation of nervous system development	GO:0051962	221	0.014
norepinephrine secretion	GO:0048243	2	0.014
defense response to virus	GO:0051607	68	0.014
regulation of camp biosynthetic process	GO:0030817	25	0.014
cellular response to acid chemical	GO:0071229	68	0.014
gtp metabolic process	GO:0046039	144	0.014
glucose metabolic process	GO:0006006	92	0.014
cellular polysaccharide metabolic process	GO:0044264	38	0.014
bone resorption	GO:0045453	38	0.014
embryonic organ morphogenesis	GO:0048562	276	0.014
negative regulation of cellular protein metabolic process	GO:0032269	247	0.014
single organismal cell cell adhesion	GO:0016337	131	0.014
negative regulation of cell development	GO:0010721	169	0.014
negative regulation of cellular amine metabolic process	GO:0033239	1	0.014
central nervous system neuron development	GO:0021954	67	0.014
cellular response to oxidative stress	GO:0034599	76	0.014
regulation of muscle system process	GO:0090257	80	0.014
protein import	GO:0017038	101	0.014
l glutamate transport	GO:0015813	16	0.014
regulation of erk1 and erk2 cascade	GO:0070372	71	0.014
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure	GO:0002025	3	0.014
cellular metal ion homeostasis	GO:0006875	151	0.013
regulation of metal ion transport	GO:0010959	106	0.013
forebrain neuron development	GO:0021884	30	0.013
cell substrate adhesion	GO:0031589	130	0.013
macromolecule catabolic process	GO:0009057	281	0.013
response to molecule of bacterial origin	GO:0002237	143	0.013
negative regulation of neuron apoptotic process	GO:0043524	92	0.013
mitochondrion organization	GO:0007005	134	0.013	Mouse
regulation of ossification	GO:0030278	112	0.013
somatostatin receptor signaling pathway	GO:0038169	2	0.013
hexose metabolic process	GO:0019318	98	0.013
hindbrain morphogenesis	GO:0021575	46	0.013
positive regulation of nucleoside metabolic process	GO:0045979	91	0.013
regulation of actin cytoskeleton organization	GO:0032956	84	0.013
regulation of cytokine production	GO:0001817	266	0.013
presynaptic membrane organization	GO:0097090	8	0.013
negative regulation of growth	GO:0045926	99	0.013
cytokine production	GO:0001816	319	0.013
cellular macromolecule catabolic process	GO:0044265	206	0.013
guanosine containing compound catabolic process	GO:1901069	144	0.013
ear morphogenesis	GO:0042471	118	0.013
serotonin uptake	GO:0051610	3	0.013
negative regulation of hormone metabolic process	GO:0032351	4	0.013
nucleoside catabolic process	GO:0009164	206	0.013
positive regulation of amine transport	GO:0051954	8	0.013
positive regulation of ossification	GO:0045778	47	0.013
small molecule catabolic process	GO:0044282	71	0.013
lipid transport	GO:0006869	98	0.013
positive regulation of purine nucleotide biosynthetic process	GO:1900373	26	0.013
membrane depolarization	GO:0051899	64	0.013
regulation of postsynaptic membrane potential	GO:0060078	48	0.013
nucleotide biosynthetic process	GO:0009165	78	0.013
positive regulation of growth hormone secretion	GO:0060124	3	0.013
t cell activation	GO:0042110	289	0.013
carbohydrate derivative catabolic process	GO:1901136	231	0.012
developmental growth involved in morphogenesis	GO:0060560	138	0.012
response to inorganic substance	GO:0010035	96	0.012
lateral inhibition	GO:0046331	1	0.012
apoptotic signaling pathway	GO:0097190	306	0.012
regulation of nucleotide catabolic process	GO:0030811	122	0.012
positive regulation of camp mediated signaling	GO:0043950	3	0.012
response to amphetamine	GO:0001975	16	0.012
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.012
regulation of nucleotide biosynthetic process	GO:0030808	34	0.012
cellular response to hormone stimulus	GO:0032870	150	0.012
neuromuscular process	GO:0050905	99	0.012
regulation of ras protein signal transduction	GO:0046578	114	0.012
general adaptation syndrome	GO:0051866	2	0.012
regulation of establishment of protein localization	GO:0070201	181	0.012
regulation of smooth muscle contraction	GO:0006940	22	0.012
metencephalon development	GO:0022037	89	0.012
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.012

Slc22a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.029
nervous system disease	DOID:863	0.029
central nervous system disease	DOID:331	0.029
disease of metabolism	DOID:0014667	0.013
disease of cellular proliferation	DOID:14566	0.012
cancer	DOID:162	0.012

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