Mus musculus

0 known processes

C1rb

complement component 1, r subcomponent B

(Aliases: mC1rB,Gm8551)

C1rb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein activation cascadeGO:0072376190.673
activation of immune responseGO:00022531380.398
complement activationGO:0006956160.288
complement activation lectin pathwayGO:000186750.257
immune effector processGO:00022523210.231
innate immune responseGO:00450871570.205
protein processingGO:00164851630.130
humoral immune responseGO:0006959570.113
regulation of cytokine productionGO:00018172660.090
lipid biosynthetic processGO:00086101790.067
protein maturationGO:00516041760.062
negative regulation of protein metabolic processGO:00512482820.062
cell adhesionGO:00071553290.062
regulation of hydrolase activityGO:00513362460.054
negative regulation of molecular functionGO:00440922580.053
cellular amine metabolic processGO:0044106440.052
negative regulation of cellular protein metabolic processGO:00322692470.052
regulation of endopeptidase activityGO:0052548890.052
negative regulation of proteolysisGO:0045861740.052
oxidation reduction processGO:00551143420.052
defense response to other organismGO:00985421970.051
organic hydroxy compound metabolic processGO:19016152030.046
positive regulation of defense responseGO:00313491240.044
negative regulation of complement activationGO:004591630.042
activation of innate immune responseGO:0002218560.042
regulation of proteolysisGO:00301621640.041
negative regulation of cell proliferationGO:00082852960.041
negative regulation of protein maturationGO:1903318790.041
organonitrogen compound biosynthetic processGO:19015661920.040
amine metabolic processGO:0009308450.037
regulation of peptidase activityGO:0052547960.036
positive regulation of cytokine productionGO:00018191740.036
carbohydrate derivative catabolic processGO:19011362310.036
regulation of secretionGO:00510462740.035
organic cyclic compound catabolic processGO:19013612950.035
ribose phosphate metabolic processGO:00196932910.035
regulation of cellular ketone metabolic processGO:0010565660.035
regulation of complement activationGO:003044970.035
cholesterol metabolic processGO:0008203560.034
regulation of cellular catabolic processGO:00313292420.033
lymphocyte proliferationGO:00466511640.033
regulation of cellular amine metabolic processGO:0033238200.033
nucleotide metabolic processGO:00091173320.033
cytokine productionGO:00018163190.033
nucleoside phosphate metabolic processGO:00067533380.032
extracellular matrix organizationGO:00301981470.031
transmembrane transportGO:00550854120.031
cellular amino acid metabolic processGO:00065201030.030
cytoplasmic transportGO:00164822340.030
extracellular structure organizationGO:00430621480.030
sterol metabolic processGO:0016125580.030
purine nucleotide metabolic processGO:00061633020.030
positive regulation of cellular amine metabolic processGO:003324050.029
cellular ketone metabolic processGO:0042180840.028
gland developmentGO:00487323300.027
fatty acid metabolic processGO:00066311210.027
negative regulation of immune system processGO:00026832090.027
regulation of organelle organizationGO:00330432890.027
response to lipopolysaccharideGO:00324961280.027
regulation of protein processingGO:0070613960.027
posttranscriptional regulation of gene expressionGO:00106081550.026
nucleoside phosphate catabolic processGO:19012922220.026
epithelial cell proliferationGO:00506731740.026
cellular response to cytokine stimulusGO:00713451890.026
purine nucleoside triphosphate metabolic processGO:00091442260.025
nucleobase containing small molecule metabolic processGO:00550863520.025
regulation of defense responseGO:00313472330.025
membrane organizationGO:00610242450.025
negative regulation of phosphorus metabolic processGO:00105631840.025
purine containing compound metabolic processGO:00725213110.025
spermatogenesisGO:00072832840.025
cellular response to dna damage stimulusGO:00069742070.024
alcohol metabolic processGO:00060661160.024
protein modification by small protein conjugation or removalGO:00706472070.023
leukocyte differentiationGO:00025213420.023
response to organic cyclic compoundGO:00140701980.023
negative regulation of t cell activationGO:0050868650.023
macromolecule catabolic processGO:00090572810.023
aromatic compound catabolic processGO:00194392860.023
regulation of protein transportGO:00512231630.023
angiogenesisGO:00015252010.023
cellular lipid metabolic processGO:00442553230.023
regulation of cellular component biogenesisGO:00440871810.023
regulation of innate immune responseGO:0045088910.022
cellular response to molecule of bacterial originGO:0071219830.022
muscle cell differentiationGO:00426922610.022
inflammatory responseGO:00069542440.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
small molecule catabolic processGO:0044282710.022
nucleoside triphosphate catabolic processGO:00091432050.022
ribonucleotide metabolic processGO:00092592910.022
cell substrate adhesionGO:00315891300.022
positive regulation of protein modification processGO:00314012990.022
carbohydrate metabolic processGO:00059752300.021
protein modification by small protein conjugationGO:00324461870.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
nucleoside metabolic processGO:00091162460.021
protein localization to organelleGO:00333651850.021
leukocyte proliferationGO:00706611720.021
response to organonitrogen compoundGO:00102432460.020
regulation of inflammatory responseGO:00507271470.020
glycosyl compound catabolic processGO:19016582060.020
neuron deathGO:00709971540.020
regulation of lymphocyte proliferationGO:00506701170.020
heterocycle catabolic processGO:00467002800.020
monocarboxylic acid metabolic processGO:00327871910.020
cellular nitrogen compound catabolic processGO:00442702800.020
ribonucleotide catabolic processGO:00092612080.020
nucleotide catabolic processGO:00091662170.020
purine ribonucleoside metabolic processGO:00461282410.020
nucleoside triphosphate metabolic processGO:00091412300.020
ribonucleoside metabolic processGO:00091192450.020
purine nucleoside metabolic processGO:00422782410.020
positive regulation of cell deathGO:00109422240.020
positive regulation of programmed cell deathGO:00430682180.020
regulation of establishment of protein localizationGO:00702011810.019
response to radiationGO:00093141650.019
reactive oxygen species metabolic processGO:0072593840.019
negative regulation of phosphorylationGO:00423261660.019
organic acid biosynthetic processGO:0016053860.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
carbohydrate derivative biosynthetic processGO:19011371830.019
t cell activationGO:00421102890.019
antibacterial peptide productionGO:000277820.019
cation transportGO:00068123990.019
male gamete generationGO:00482322850.019
negative regulation of cellular amine metabolic processGO:003323910.019
cellular response to lipidGO:00713961450.019
lymphocyte mediated immunityGO:00024491390.018
cellular homeostasisGO:00197252400.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
muscle tissue developmentGO:00605373080.018
positive regulation of protein phosphorylationGO:00019342420.018
anion transportGO:00068201770.018
intracellular protein transportGO:00068862040.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
urogenital system developmentGO:00016552610.018
apoptotic signaling pathwayGO:00971903060.018
leukocyte mediated immunityGO:00024431740.018
negative regulation of endopeptidase activityGO:0010951440.017
purine ribonucleotide catabolic processGO:00091542080.017
glycosyl compound metabolic processGO:19016572460.017
nuclear importGO:0051170950.017
steroid metabolic processGO:00082021190.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
regulation of hormone levelsGO:00108172110.017
ribonucleoside catabolic processGO:00424542060.017
small molecule biosynthetic processGO:00442831320.017
protein ubiquitinationGO:00165671710.017
camera type eye developmentGO:00430102660.017
reactive oxygen species biosynthetic processGO:190340980.017
regulation of cell activationGO:00508652890.017
ear developmentGO:00435832000.017
antibacterial peptide biosynthetic processGO:000278020.017
peptide metabolic processGO:0006518460.016
negative regulation of protein activation cascadeGO:200025830.016
interleukin 8 productionGO:003263740.016
regulation of cellular response to stressGO:00801351590.016
homeostasis of number of cellsGO:00488722100.016
cellular chemical homeostasisGO:00550822150.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
nucleoside catabolic processGO:00091642060.016
protein targetingGO:00066051430.016
purine ribonucleotide metabolic processGO:00091502900.016
regulation of lipid metabolic processGO:00192161180.016
epithelial tube morphogenesisGO:00605623030.016
organonitrogen compound catabolic processGO:19015652640.016
nuclear transportGO:00511691390.016
compound eye developmentGO:004874910.016
myeloid leukocyte differentiationGO:00025731190.016
production of molecular mediator of immune responseGO:00024401030.016
kidney developmentGO:00018222130.016
regulation of lymphocyte activationGO:00512492400.016
regulation of secretion by cellGO:19035302490.016
nitrogen compound transportGO:00717052710.016
endocytosisGO:00068971680.015
negative regulation of hydrolase activityGO:0051346710.015
regulation of response to woundingGO:19030341890.015
nucleocytoplasmic transportGO:00069131390.015
glial cell apoptotic processGO:003434930.015
mapk cascadeGO:00001652810.015
ossificationGO:00015032160.015
phagocytosisGO:0006909660.015
purine nucleotide catabolic processGO:00061952110.015
regulation of protein maturationGO:1903317960.015
ion transmembrane transportGO:00342203610.015
immune response activating signal transductionGO:00027571160.015
myeloid cell differentiationGO:00300992330.015
negative regulation of defense responseGO:0031348770.015
regulation of apoptotic signaling pathwayGO:20012331970.015
cellular response to interferon betaGO:0035458210.015
cation transmembrane transportGO:00986552660.015
cellular response to growth factor stimulusGO:00713631970.015
purine nucleoside catabolic processGO:00061522050.015
purine ribonucleoside catabolic processGO:00461302050.015
negative regulation of cytokine productionGO:0001818840.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
cellular response to biotic stimulusGO:0071216920.014
regulation of system processGO:00440572000.014
triglyceride metabolic processGO:0006641510.014
pattern recognition receptor signaling pathwayGO:0002221470.014
positive regulation of kinase activityGO:00336741550.014
defense response to bacteriumGO:00427421190.014
negative regulation of protein modification processGO:00314001630.014
sulfur compound metabolic processGO:00067901000.014
regulation of neuron differentiationGO:00456642810.014
regulation of purine nucleotide metabolic processGO:19005421690.014
regulation of cellular amino acid metabolic processGO:000652150.014
regulation of cell cycleGO:00517262810.014
cellular response to lipopolysaccharideGO:0071222770.014
protein import into nucleusGO:0006606950.014
glial cell differentiationGO:00100011310.014
response to steroid hormoneGO:0048545560.014
negative regulation of cellular component organizationGO:00511291940.014
cation homeostasisGO:00550802120.014
developmental maturationGO:00217001930.014
inorganic ion transmembrane transportGO:00986602340.014
monocarboxylic acid biosynthetic processGO:0072330610.014
regulation of multi organism processGO:00439001110.014
positive regulation of apoptotic cell clearanceGO:200042730.013
response to molecule of bacterial originGO:00022371430.013
carbohydrate homeostasisGO:00335001280.013
nucleoside monophosphate metabolic processGO:0009123850.013
engulfment of apoptotic cellGO:004365230.013
circulatory system processGO:00030131970.013
regulation of glucose metabolic processGO:0010906600.013
immune response regulating signaling pathwayGO:00027641250.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
carboxylic acid biosynthetic processGO:0046394860.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
purine containing compound catabolic processGO:00725232130.013
cell type specific apoptotic processGO:00972852680.013
organophosphate biosynthetic processGO:00904071220.013
regulation of epithelial cell proliferationGO:00506781410.013
gliogenesisGO:00420631410.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
anatomical structure homeostasisGO:00602491450.013
organic anion transportGO:00157111370.013
regulation of nucleotide metabolic processGO:00061401690.013
positive regulation of secretion by cellGO:19035321140.013
positive regulation of cytokine secretionGO:0050715410.013
regulation of mapk cascadeGO:00434082480.013
regulation of body fluid levelsGO:00508781620.013
t cell proliferationGO:00420981200.013
dna metabolic processGO:00062593030.013
regulation of transferase activityGO:00513382630.013
connective tissue developmentGO:00614481790.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
regulation of membrane potentialGO:00423911920.013
regulation of ossificationGO:00302781120.013
regulation of intracellular transportGO:00323861590.012
negative regulation of epithelial cell proliferationGO:0050680640.012
regulation of cell projection organizationGO:00313442060.012
response to nutrient levelsGO:00316671090.012
protein catabolic processGO:00301632210.012
regulation of defense response to bacteriumGO:190042430.012
regulation of t cell activationGO:00508631700.012
fat soluble vitamin biosynthetic processGO:004236240.012
regulation of leukocyte proliferationGO:00706631210.012
organelle localizationGO:00516401790.012
rho protein signal transductionGO:0007266320.012
activation of nf kappab inducing kinase activityGO:000725040.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
epithelial cell developmentGO:00020641590.012
regulation of cytoskeleton organizationGO:00514931220.012
neuron apoptotic processGO:00514021420.012
regulation of osteoblast differentiationGO:0045667670.012
lipid transportGO:0006869980.012
modification dependent protein catabolic processGO:00199411330.012
skeletal system developmentGO:00015013560.012
actin cytoskeleton organizationGO:00300362200.012
positive regulation of protein kinase activityGO:00458601440.012
cellular response to organonitrogen compoundGO:00714171450.012
lung developmentGO:00303241640.012
antimicrobial peptide productionGO:000277520.012
regulation of lymphocyte mediated immunityGO:0002706840.012
sensory perceptionGO:00076002450.012
glycerolipid metabolic processGO:00464861220.012
endomembrane system organizationGO:00102561470.012
small gtpase mediated signal transductionGO:0007264970.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
cellular macromolecule catabolic processGO:00442652060.011
ras protein signal transductionGO:0007265770.011
positive regulation of innate immune responseGO:0045089800.011
regulation of interleukin 8 productionGO:003267730.011
response to growth factorGO:00708481980.011
negative regulation of cell cycleGO:00457861230.011
regulation of protein catabolic processGO:00421761080.011
positive regulation of interferon alpha productionGO:003272740.011
regulation of kinase activityGO:00435492490.011
amide transportGO:00428861380.011
regulation of response to biotic stimulusGO:0002831380.011
cellular response to extracellular stimulusGO:0031668810.011
regulation of carbohydrate metabolic processGO:0006109750.011
microtubule cytoskeleton organizationGO:00002261570.011
protein secretionGO:00093061110.011
positive regulation of cellular catabolic processGO:00313311480.011
regulation of cell migrationGO:00303342190.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
microtubule based processGO:00070172360.011
single organism nuclear importGO:1902593950.011
regulation of protein localizationGO:00328802310.011
mitotic cell cycleGO:00002781950.011
positive regulation of activation of membrane attack complexGO:000197020.011
maintenance of locationGO:0051235890.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
guanosine containing compound catabolic processGO:19010691440.011
protein glycosylationGO:0006486550.011
positive regulation of osteoblast differentiationGO:0045669340.011
positive regulation of hydrolase activityGO:00513451480.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
negative regulation of protein phosphorylationGO:00019331260.011
striated muscle tissue developmentGO:00147062930.011
inorganic cation transmembrane transportGO:00986622070.011
glucose transportGO:0015758560.011
regulation of cell adhesionGO:00301551540.011
regulation of anatomical structure sizeGO:00900661780.011
cellular carbohydrate metabolic processGO:00442621190.011
regulation of purine nucleotide catabolic processGO:00331211220.011
glycoprotein biosynthetic processGO:0009101890.011
divalent inorganic cation transportGO:00725111780.011
positive regulation of nucleotide metabolic processGO:00459811140.011
gtp metabolic processGO:00460391440.011
monosaccharide metabolic processGO:00059961060.011
blood circulationGO:00080151950.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
organophosphate catabolic processGO:00464342320.011
rna interferenceGO:001624620.011
regulation of protein serine threonine kinase activityGO:00719001570.010
cellular protein catabolic processGO:00442571550.010
axonogenesisGO:00074092740.010
skin developmentGO:00435882200.010
regulation of intracellular protein transportGO:0033157820.010
response to acid chemicalGO:00011011110.010
hormone secretionGO:00468791280.010
spermatid differentiationGO:00485151150.010
regulation of nucleocytoplasmic transportGO:0046822730.010
regulation of ion transportGO:00432692150.010
negative regulation of growthGO:0045926990.010
mitochondrion organizationGO:00070051340.010
hematopoietic progenitor cell differentiationGO:00022441430.010
regulation of interleukin 8 secretionGO:200048220.010
activation of membrane attack complexGO:000190540.010
midgut developmentGO:000749440.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
sequestering of metal ionGO:0051238190.010
response to organophosphorusGO:0046683220.010
negative regulation of leukocyte differentiationGO:1902106510.010
localization within membraneGO:005166840.010
negative regulation of phosphate metabolic processGO:00459361840.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
ubiquitin dependent protein catabolic processGO:00065111290.010
regulation of autophagyGO:0010506300.010

C1rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.090
disease of anatomical entityDOID:700.090
hemolytic anemiaDOID:58300.075
hematopoietic system diseaseDOID:7400.075
normocytic anemiaDOID:72000.075
hemolytic uremic syndromeDOID:1255400.075
anemiaDOID:235500.075
immune system diseaseDOID:291400.075
eye diseaseDOID:561400.072
retinal diseaseDOID:567900.072
eye and adnexa diseaseDOID:149200.072
sensory system diseaseDOID:005015500.072
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.017
macular degenerationDOID:444800.012
retinal degenerationDOID:846600.012
integumentary system diseaseDOID:1600.012
musculoskeletal system diseaseDOID:1700.011
age related macular degenerationDOID:1087100.010
degeneration of macula and posterior poleDOID:200700.010
neurodegenerative diseaseDOID:128900.010
central nervous system diseaseDOID:33100.010