Mus musculus

50 known processes

Mdm2

transformed mouse 3T3 cell double minute 2

(Aliases: AA415488,1700007J15Rik,Mdm-2)

Mdm2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742071.000
Human
signal transduction by p53 class mediatorGO:0072331511.000
Human
signal transduction involved in mitotic dna damage checkpointGO:190240231.000
Human
negative regulation of nik nf kappab signalingGO:190122321.000
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332351.000
negative regulation of cell cycleGO:00457861230.999
Human Zebrafish
regulation of protein stabilityGO:0031647520.999
Human
apoptotic signaling pathwayGO:00971903060.999
cell cycle arrestGO:0007050370.999
Human Zebrafish
modification dependent macromolecule catabolic processGO:00436321330.999
Human
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascadeGO:003816810.998
extrinsic apoptotic signaling pathwayGO:00971911260.998
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.998
cellular response to gamma radiationGO:007148040.997
protein modification by small protein conjugationGO:00324461870.997
protein modification by small protein conjugation or removalGO:00706472070.996
modification dependent protein catabolic processGO:00199411330.996
Human
dna damage response signal transduction by p53 class mediatorGO:0030330190.996
Human
dna metabolic processGO:00062593030.995
regulation of cell cycleGO:00517262810.993
covalent chromatin modificationGO:00165691630.992
signal transduction involved in dna integrity checkpointGO:007240130.989
Human
intrinsic apoptotic signaling pathwayGO:00971931320.989
ubiquitin dependent protein catabolic processGO:00065111290.989
Human
regulation of mitotic cell cycle phase transitionGO:1901990730.989
peptidyl threonine phosphorylationGO:0018107310.987
protein ubiquitinationGO:00165671710.987
protein autophosphorylationGO:0046777610.984
negative regulation of phosphorylationGO:00423261660.984
signal transduction involved in cell cycle checkpointGO:007239530.982
Human
positive regulation of protein modification processGO:00314012990.980
negative regulation of cell proliferationGO:00082852960.976
endothelial cell apoptotic processGO:007257790.976
regulation of cell cycle processGO:00105641600.973
positive regulation of programmed cell deathGO:00430682180.972
regulation of cellular catabolic processGO:00313292420.970
Human
negative regulation of map kinase activityGO:0043407340.969
proteasomal protein catabolic processGO:0010498980.963
Human
regulation of transferase activityGO:00513382630.963
protein localization to organelleGO:00333651850.957
Human
voluntary musculoskeletal movementGO:005088230.951
regulation of protein kinase activityGO:00458592320.951
cell cycle g1 s phase transitionGO:0044843570.945
chromatin organizationGO:00063252060.941
positive regulation of apoptotic processGO:00430652170.940
mitotic cell cycle arrestGO:007185040.938
histone modificationGO:00165701590.936
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.929
proteolysis involved in cellular protein catabolic processGO:00516031470.929
Human
regulation of response to dna damage stimulusGO:2001020340.928
Human
regulation of leukocyte differentiationGO:19021051590.926
negative regulation of protein serine threonine kinase activityGO:0071901490.924
organelle fissionGO:00482851700.924
regulation of mitotic cell cycleGO:00073461260.923
negative regulation of kinase activityGO:0033673810.920
glial cell apoptotic processGO:003434930.914
negative regulation of intracellular signal transductionGO:19025321670.912
Human
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.910
Human
negative regulation of phosphatidylinositol 3 kinase activityGO:004355310.907
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activityGO:003816710.905
positive regulation of apoptotic signaling pathwayGO:2001235950.903
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.899
Human
traversing start control point of mitotic cell cycleGO:000708920.898
cellular response to transforming growth factor beta stimulusGO:0071560880.897
regulation of cell cycle g1 s phase transitionGO:1902806350.893
negative regulation of cellular protein metabolic processGO:00322692470.893
regionalizationGO:00030023370.892
positive regulation of protein phosphorylationGO:00019342420.886
g1 s transition of mitotic cell cycleGO:0000082570.882
negative regulation of phosphate metabolic processGO:00459361840.882
macroautophagyGO:0016236210.882
cellular protein catabolic processGO:00442571550.881
Human
regulation of apoptotic signaling pathwayGO:20012331970.880
peptidyl serine modificationGO:0018209830.880
cell cycle checkpointGO:0000075470.879
Human
posttranscriptional regulation of gene expressionGO:00106081550.879
Human
protein processingGO:00164851630.878
protein catabolic processGO:00301632210.877
positive regulation of transferase activityGO:00513471670.877
mitotic g1 dna damage checkpointGO:003157140.874
Human
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.867
mitotic cell cycleGO:00002781950.865
ras protein signal transductionGO:0007265770.865
signal transduction in response to dna damageGO:0042770210.863
Human
regulation of protein maturationGO:1903317960.863
regulation of cellular response to stressGO:00801351590.863
Human
negative regulation of cell cycle processGO:0010948690.860
Human Zebrafish
cellular response to growth factor stimulusGO:00713631970.859
regulation of cell cycle phase transitionGO:1901987770.857
response to growth factorGO:00708481980.852
positive regulation of mitotic cell cycleGO:0045931410.847
negative regulation of transferase activityGO:0051348850.844
meiotic nuclear divisionGO:00071261150.844
homeostasis of number of cellsGO:00488722100.841
signal transduction involved in mitotic dna integrity checkpointGO:190240330.834
Human
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.829
Human
regulation of osteoblast differentiationGO:0045667670.828
peptidyl amino acid modificationGO:00181933360.826
Human
meiotic cell cycleGO:00513211220.824
mitochondrial dna repairGO:004350430.822
negative regulation of epithelial cell proliferationGO:0050680640.820
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.820
regulation of protein ubiquitinationGO:0031396520.818
regulation of kinase activityGO:00435492490.808
regulation of macroautophagyGO:0016241120.807
myeloid leukocyte differentiationGO:00025731190.806
negative regulation of mapk cascadeGO:0043409650.804
dna replicationGO:0006260520.803
negative regulation of cell cycle arrestGO:007115710.799
Human Zebrafish
negative regulation of mitotic cell cycle phase transitionGO:1901991450.797
Human
protein stabilizationGO:0050821250.793
cellular senescenceGO:0090398110.789
regulation of myeloid leukocyte differentiationGO:0002761580.787
positive regulation of cellular catabolic processGO:00313311480.785
Human
meiotic cell cycle processGO:1903046770.780
regulation of chromosome organizationGO:0033044830.780
regulation of reactive oxygen species metabolic processGO:2000377400.770
positive regulation of cell cycle phase transitionGO:1901989170.765
regulation of protein catabolic processGO:00421761080.762
Human
cell agingGO:0007569350.761
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.760
jnk cascadeGO:0007254720.752
g0 to g1 transitionGO:004502330.751
telomere maintenanceGO:0000723190.749
regulation of chromatin modificationGO:1903308570.743
positive regulation of striated muscle cell apoptotic processGO:001066330.739
negative regulation of dna replicationGO:000815640.738
regulation of hippo signalingGO:003533010.737
response to light stimulusGO:00094161350.728
regulation of autophagyGO:0010506300.726
negative regulation of phosphorus metabolic processGO:00105631840.726
cellular response to decreased oxygen levelsGO:0036294180.723
Human
negative regulation of blood vessel endothelial cell migrationGO:004353730.721
negative regulation of neuron deathGO:1901215980.718
response to endoplasmic reticulum stressGO:0034976530.711
skeletal system developmentGO:00015013560.710
blastocyst growthGO:0001832230.707
negative regulation of jnk cascadeGO:0046329120.707
positive regulation of leukocyte apoptotic processGO:2000108210.704
negative regulation of jun kinase activityGO:004350890.701
positive regulation of kinase activityGO:00336741550.692
camera type eye developmentGO:00430102660.690
stress activated protein kinase signaling cascadeGO:0031098810.688
fibroblast migrationGO:0010761210.687
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.687
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.682
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.675
Human
positive regulation of cell cycle g1 s phase transitionGO:190280890.671
cellular response to hypoxiaGO:0071456170.671
Human
b cell activationGO:00421131610.666
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.661
cellular response to nitric oxideGO:007173240.654
negative regulation of protein catabolic processGO:0042177360.651
regulation of erythrocyte differentiationGO:0045646230.646
dna endoreduplicationGO:004202340.646
regulation of protein modification by small protein conjugation or removalGO:1903320570.633
osteoclast differentiationGO:0030316620.626
peptidyl threonine modificationGO:0018210310.625
peptidyl serine phosphorylationGO:0018105740.623
dna integrity checkpointGO:0031570280.622
Human
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771240.619
oocyte differentiationGO:0009994350.618
negative regulation of fibroblast migrationGO:001076420.618
positive regulation of macroautophagyGO:001623930.617
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.611
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.610
Human
negative regulation of cellular amine metabolic processGO:003323910.610
negative regulation of lipid kinase activityGO:009021910.609
positive regulation of mitotic cell cycle phase transitionGO:1901992170.608
positive regulation of protein ubiquitinationGO:0031398270.606
negative regulation of cellular amino acid metabolic processGO:004576300.603
regulation of cellular protein catabolic processGO:1903362610.603
Human
mitochondrion degradationGO:000042230.599
negative regulation of protein metabolic processGO:00512482820.588
germ cell developmentGO:00072811850.587
negative regulation of mammary gland epithelial cell proliferationGO:003360030.587
mitotic cell cycle checkpointGO:0007093310.587
Human
regulation of b cell proliferationGO:0030888390.579
cellular macromolecule catabolic processGO:00442652060.576
Human
epidermal cell divisionGO:001048130.566
regulation of g1 s transition of mitotic cell cycleGO:2000045350.566
positive regulation of reactive oxygen species metabolic processGO:2000379110.565
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.562
chromosome segregationGO:0007059480.561
muscle cell apoptotic processGO:0010657180.558
leukocyte differentiationGO:00025213420.556
hippo signalingGO:0035329110.553
erythrocyte differentiationGO:0030218880.552
nuclear divisionGO:00002801580.550
negative regulation of proteolysisGO:0045861740.550
response to hypoxiaGO:0001666580.549
Human
dendrite developmentGO:00163581150.548
dna damage checkpointGO:0000077260.547
Human
cellular response to drugGO:0035690150.546
myeloid cell differentiationGO:00300992330.544
regulation of cell cycle arrestGO:0071156120.544
Human Zebrafish
locomotory behaviorGO:00076261950.536
neuron deathGO:00709971540.534
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.530
embryonic appendage morphogenesisGO:00351131260.528
nucleotide excision repairGO:0006289130.527
negative regulation of stress activated mapk cascadeGO:0032873140.525
cellular amine metabolic processGO:0044106440.525
epithelial cell proliferationGO:00506731740.522
cellular response to oxygen levelsGO:0071453200.520
Human
negative regulation of cell growthGO:0030308440.519
regulation of neuron deathGO:19012141340.516
regulation of stress activated mapk cascadeGO:0032872690.515
cellular response to tumor necrosis factorGO:0071356210.514
negative regulation of lymphocyte activationGO:0051250910.512
activation of adenylate cyclase activityGO:000719040.503
positive regulation of keratinocyte proliferationGO:001083840.493
regulation of neuron apoptotic processGO:00435231220.490
response to x rayGO:0010165110.489
Zebrafish
autophagyGO:0006914450.481
cell divisionGO:00513011200.480
microtubule polymerization or depolymerizationGO:0031109260.476
response to tumor necrosis factorGO:0034612260.476
regulation of hydrolase activityGO:00513362460.476
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.476
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.472
negative regulation of cellular catabolic processGO:0031330470.471
mitotic cell cycle processGO:19030471590.470
positive regulation of lymphocyte apoptotic processGO:0070230130.468
retina morphogenesis in camera type eyeGO:0060042450.466
regulation of protein localization to nucleusGO:1900180600.462
regulation of cellular amine metabolic processGO:0033238200.459
response to transforming growth factor betaGO:0071559880.456
histone phosphorylationGO:001657290.453
leukocyte proliferationGO:00706611720.452
regulation of muscle cell apoptotic processGO:0010660170.446
embryonic organ morphogenesisGO:00485622760.441
response to antibioticGO:0046677110.437
Human
stress activated mapk cascadeGO:0051403800.437
negative regulation of protein maturationGO:1903318790.436
central nervous system neuron differentiationGO:00219531620.436
regulation of osteoclast differentiationGO:0045670360.430
cellular response to cytokine stimulusGO:00713451890.429
positive regulation of g1 s transition of mitotic cell cycleGO:190008790.427
reactive oxygen species metabolic processGO:0072593840.427
transforming growth factor beta receptor signaling pathwayGO:0007179710.418
positive regulation of proteolysisGO:0045862850.414
Human
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.414
regulation of organelle organizationGO:00330432890.411
methylationGO:00322591340.409
positive regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:190223160.399
reciprocal dna recombinationGO:0035825160.396
negative regulation of fibroblast proliferationGO:0048147140.394
macromolecule catabolic processGO:00090572810.391
negative regulation of protein phosphorylationGO:00019331260.389
regulation of map kinase activityGO:00434051200.389
signal transduction involved in dna damage checkpointGO:007242230.385
Human
t cell differentiation in thymusGO:0033077770.384
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.383
cellular response to toxic substanceGO:009723770.381
cohesin localization to chromatinGO:007192110.380
pole plasm assemblyGO:000731520.376
cellular response to extracellular stimulusGO:0031668810.374
fatty acid transmembrane transportGO:190200110.370
response to drugGO:0042493750.368
amine metabolic processGO:0009308450.362
limb developmentGO:00601731660.359
cellular response to radiationGO:0071478280.356
negative regulation of neuron apoptotic processGO:0043524920.354
purine ribonucleotide metabolic processGO:00091502900.354
positive regulation of cell deathGO:00109422240.353
regulation of protein serine threonine kinase activityGO:00719001570.350
regulation of sister chromatid segregationGO:0033045130.348
positive regulation of cellular amino acid metabolic processGO:004576430.347
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.344
cell fate commitmentGO:00451652100.343
multicellular organismal agingGO:0010259240.339
mitotic sister chromatid separationGO:005130690.339
cellular response to external stimulusGO:0071496880.338
negative regulation of fatty acid transportGO:200019210.337
t cell proliferation involved in immune responseGO:000230940.335
cellular amino acid metabolic processGO:00065201030.335
genetic imprintingGO:0071514270.334
male meiosis iGO:0007141160.333
cerebrospinal fluid secretionGO:003332640.330
negative regulation of leukocyte differentiationGO:1902106510.329
photoreceptor cell morphogenesisGO:000859430.328
dna recombinationGO:0006310920.327
cellular response to x rayGO:007148120.326
regulation of epithelial cell proliferationGO:00506781410.325
positive regulation of cellular amine metabolic processGO:003324050.323
cellular response to inorganic substanceGO:0071241370.320
intra s dna damage checkpointGO:003157340.319
positive regulation of protein kinase activityGO:00458601440.319
negative regulation of macroautophagyGO:001624250.319
regulation of synaptic plasticityGO:0048167870.318
oocyte developmentGO:0048599330.317
regulation of proteolysisGO:00301621640.314
Human
negative regulation of fatty acid metabolic processGO:0045922100.313
negative regulation of response to dna damage stimulusGO:2001021100.307
Human
telomere cappingGO:001623340.307
fibroblast proliferationGO:0048144350.302
negative regulation of molecular functionGO:00440922580.301
protein modification by small protein removalGO:0070646210.298
protein maturationGO:00516041760.297
developmental maturationGO:00217001930.295
regulation of intracellular protein transportGO:0033157820.293
cell type specific apoptotic processGO:00972852680.292
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.287
cellular response to starvationGO:0009267570.280
negative regulation of leukocyte proliferationGO:0070664460.279
female gamete generationGO:0007292740.277
notch signaling pathwayGO:0007219710.277
negative regulation of reactive oxygen species metabolic processGO:2000378100.276
mammary gland epithelium developmentGO:0061180650.272
positive regulation of mitotic sister chromatid separationGO:190197020.271
response to reactive oxygen speciesGO:0000302560.270
neuron apoptotic processGO:00514021420.268
tissue remodelingGO:00487711020.266
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225520.265
regulation of dna bindingGO:0051101390.264
metaphase anaphase transition of mitotic cell cycleGO:000709190.263
regulation of cytoplasmic transportGO:19036491120.262
adult behaviorGO:00305341350.260
positive regulation of smooth muscle cell migrationGO:001491140.259
striated muscle cell apoptotic processGO:0010658120.259
positive regulation of protein autophosphorylationGO:003195440.258
peptidyl tyrosine modificationGO:00182121450.255
erbb signaling pathwayGO:0038127320.255
apoptotic process involved in mammary gland involutionGO:006005740.255
negative regulation of lymphocyte proliferationGO:0050672450.254
negative regulation of cellular response to growth factor stimulusGO:0090288460.254
regulation of dna templated transcription in response to stressGO:004362090.251
negative regulation of neural precursor cell proliferationGO:2000178180.248
histone h4 k16 acetylationGO:004398430.245
small gtpase mediated signal transductionGO:0007264970.245
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.239
b cell proliferationGO:0042100530.238
oocyte maturationGO:0001556180.236
skeletal muscle organ developmentGO:00605381630.236
negative regulation of dna damage response signal transduction by p53 class mediatorGO:004351850.235
Human
cation transportGO:00068123990.235
positive regulation of cell cycle processGO:0090068610.234
positive regulation of cell cycleGO:0045787920.233
positive regulation of release of cytochrome c from mitochondriaGO:009020050.230
regulation of cellular ketone metabolic processGO:0010565660.227
mitochondrial membrane organizationGO:0007006260.225
positive regulation of nucleotide metabolic processGO:00459811140.223
positive regulation of bindingGO:0051099490.222
activation of mapk activityGO:0000187590.219
appendage developmentGO:00487361660.219
mitochondrion distributionGO:004831140.217
regulation of cyclic nucleotide metabolic processGO:0030799400.216
response to inorganic substanceGO:0010035960.214
cellular response to light stimulusGO:0071482190.213
negative regulation of endothelial cell migrationGO:001059640.212
cellular response to antibioticGO:007123640.211
positive regulation of mitochondrion organizationGO:0010822170.210
regulation of mitosisGO:0007088290.210
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.210
Human
regulation of ion transmembrane transportGO:00347651190.210
t cell activationGO:00421102890.208
retina development in camera type eyeGO:00600411190.208
positive regulation of autophagyGO:001050890.207
ribonucleoside catabolic processGO:00424542060.207
negative regulation of organ growthGO:0046621170.207
response to nitric oxideGO:007173140.206
chromatin modificationGO:00165681870.205
oocyte axis specificationGO:000730920.204
dna damage response signal transduction resulting in transcriptionGO:004277220.204
dendritic spine morphogenesisGO:0060997220.203
negative regulation of apoptotic signaling pathwayGO:20012341040.202
regulation of protein localizationGO:00328802310.200
positive regulation of macrophage apoptotic processGO:200011130.199
positive regulation of peptidase activityGO:0010952490.199
negative regulation of growthGO:0045926990.199
regulation of mesoderm developmentGO:2000380120.198
neuron projection guidanceGO:00974851410.197
release of cytochrome c from mitochondriaGO:0001836230.197
response to oxygen levelsGO:0070482620.194
Human
regulation of histone modificationGO:0031056560.194
cellular response to nutrient levelsGO:0031669640.194
positive regulation of growthGO:00459271040.194
b cell lineage commitmentGO:000232640.194
purine containing compound metabolic processGO:00725213110.193
cellular response to oxidative stressGO:0034599760.191
negative regulation of cellular protein catabolic processGO:1903363220.191
positive regulation of protein serine threonine kinase activityGO:00719021060.189
regulation of jun kinase activityGO:0043506400.189
regulation of purine nucleotide metabolic processGO:19005421690.189
regulation of jnk cascadeGO:0046328620.187
aromatic compound catabolic processGO:00194392860.186
cell growthGO:00160491300.186
regulation of peptidase activityGO:0052547960.185
lymphocyte proliferationGO:00466511640.185
regulation of microtubule polymerizationGO:003111370.184
regulation of bindingGO:00510981110.184
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.183
phosphatidylinositol biosynthetic processGO:0006661150.183
compound eye developmentGO:004874910.182
regulation of nucleotide metabolic processGO:00061401690.181
dendritic spine developmentGO:0060996300.180
regulation of mapk cascadeGO:00434082480.179
attachment of spindle microtubules to kinetochoreGO:000860840.179
translationGO:0006412930.178
mitotic sister chromatid segregationGO:0000070140.177
regulation of intracellular transportGO:00323861590.177
negative regulation of mitotic cell cycleGO:0045930580.176
Human
cognitionGO:00508901490.176
regulation of cell sizeGO:0008361720.174
positive regulation of response to dna damage stimulusGO:2001022140.174
positive regulation of histone modificationGO:0031058280.173
tor signalingGO:0031929210.171
response to nutrient levelsGO:00316671090.171
response to radiationGO:00093141650.170
Zebrafish
anatomical structure homeostasisGO:00602491450.169
embryonic skeletal system developmentGO:00487061200.168
regulation of leukocyte proliferationGO:00706631210.168
apoptotic mitochondrial changesGO:0008637480.166
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.165
positive regulation of hydrolase activityGO:00513451480.165
bone developmentGO:00603481200.164
regulation of fibrinolysisGO:005191710.163
second messenger mediated signalingGO:0019932730.163
negative regulation of synaptic vesicle exocytosisGO:200030130.162
hematopoietic progenitor cell differentiationGO:00022441430.162
membrane organizationGO:00610242450.162
myeloid cell homeostasisGO:00022621140.161
regulation of fibroblast proliferationGO:0048145340.161
monocarboxylic acid metabolic processGO:00327871910.160
positive regulation of neuron apoptotic processGO:0043525250.158
cyclic nucleotide metabolic processGO:0009187590.158
engulfment of apoptotic cellGO:004365230.157
regulation of cellular amino acid metabolic processGO:000652150.157
regulation of mammary gland epithelial cell proliferationGO:0033599120.156
negative regulation of protein modification processGO:00314001630.153
chromatin assemblyGO:0031497130.153
regulation of epidermal cell divisionGO:001048230.152
negative regulation of b cell activationGO:0050869270.152
negative regulation of epithelial cell proliferation involved in prostate gland developmentGO:006077070.151
immunoglobulin productionGO:0002377730.151
protein kinase b signalingGO:0043491740.151
mapk cascadeGO:00001652810.150
blastocyst developmentGO:0001824800.150
cytokine mediated signaling pathwayGO:00192211150.149
oocyte constructionGO:000730820.147
regulation of lymphocyte proliferationGO:00506701170.147
columnar cuboidal epithelial cell differentiationGO:0002065820.146
stem cell differentiationGO:00488632680.146
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.144
mitotic g2 dna damage checkpointGO:000709580.144
regulation of sequence specific dna binding transcription factor activityGO:00510901060.144
negative regulation of immune system processGO:00026832090.144
regulation of ion transportGO:00432692150.143
positive regulation of cell motilityGO:20001471160.143
purine nucleotide metabolic processGO:00061633020.141
immature b cell differentiationGO:0002327100.141
g2 dna damage checkpointGO:003157280.140
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.140
negative regulation of cell divisionGO:0051782240.139
central nervous system projection neuron axonogenesisGO:0021952210.139
axon guidanceGO:00074111410.138
positive regulation of mitotic metaphase anaphase transitionGO:004584220.137
regulation of mitochondrion degradationGO:190314620.136
regulation of cell activationGO:00508652890.136
cytokinesisGO:0000910170.136
dna alkylationGO:0006305430.135
double strand break repairGO:0006302480.135
neuron maturationGO:0042551290.135
embryonic retina morphogenesis in camera type eyeGO:006005970.135
regulation of defense responseGO:00313472330.135
regulation of plasminogen activationGO:001075540.134
positive regulation of rac protein signal transductionGO:003502210.134
response to extracellular stimulusGO:00099911270.133
ion transmembrane transportGO:00342203610.132
negative regulation of angiogenesisGO:0016525250.132

Mdm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.998
cancerDOID:16200.990
organ system cancerDOID:005068600.990
thoracic cancerDOID:509300.898
endocrine gland cancerDOID:17000.885
immune system diseaseDOID:291400.696
disease of anatomical entityDOID:700.696
bone marrow diseaseDOID:496100.696
hematopoietic system diseaseDOID:7400.696
large intestine cancerDOID:567200.644
colon cancerDOID:21900.644
gastrointestinal system cancerDOID:311900.644
intestinal cancerDOID:1015500.644
colorectal cancerDOID:925600.644
pancreatic cancerDOID:179300.502
immune system cancerDOID:006008300.423
breast cancerDOID:161200.374
male reproductive organ cancerDOID:385600.327
reproductive organ cancerDOID:19300.327
hematologic cancerDOID:253100.309
respiratory system cancerDOID:005061500.192
lung cancerDOID:132400.192
urinary system cancerDOID:399600.192
colon carcinomaDOID:152000.156