Mus musculus

11 known processes

Mdm4

transformed mouse 3T3 cell double minute 4

(Aliases: AU018793,4933417N07Rik,Mdmx,AL023055,AU021806,AA414968,C85810)

Mdm4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.999
Human
signal transduction involved in mitotic dna damage checkpointGO:190240230.994
dna metabolic processGO:00062593030.991
negative regulation of cell cycle arrestGO:007115710.972
negative regulation of cell cycleGO:00457861230.966
signal transduction involved in dna integrity checkpointGO:007240130.962
signal transduction by p53 class mediatorGO:0072331510.958
Human
cellular response to gamma radiationGO:007148040.958
protein modification by small protein conjugation or removalGO:00706472070.931
Mouse
dna repairGO:00062811070.927
modification dependent macromolecule catabolic processGO:00436321330.910
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.907
protein modification by small protein conjugationGO:00324461870.899
Mouse
signal transduction involved in dna damage checkpointGO:007242230.896
chromatin modificationGO:00165681870.879
positive regulation of apoptotic processGO:00430652170.867
negative regulation of mitotic cell cycleGO:0045930580.861
regulation of protein stabilityGO:0031647520.859
Human
negative regulation of phosphorylationGO:00423261660.857
signal transduction involved in mitotic dna integrity checkpointGO:190240330.852
mitotic g1 dna damage checkpointGO:003157140.846
protein maturationGO:00516041760.845
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.842
response to x rayGO:0010165110.826
proteolysis involved in cellular protein catabolic processGO:00516031470.800
signal transduction involved in cell cycle checkpointGO:007239530.798
traversing start control point of mitotic cell cycleGO:000708920.788
Mouse
negative regulation of dna replicationGO:000815640.765
ubiquitin dependent protein catabolic processGO:00065111290.764
regulation of mitotic cell cycle phase transitionGO:1901990730.756
Mouse
g1 s transition of mitotic cell cycleGO:0000082570.742
Mouse
regulation of cell cycleGO:00517262810.737
Mouse
negative regulation of nik nf kappab signalingGO:190122320.734
cell cycle checkpointGO:0000075470.728
protein processingGO:00164851630.725
modification dependent protein catabolic processGO:00199411330.719
positive regulation of cell cycle g1 s phase transitionGO:190280890.716
Mouse
negative regulation of dna damage response signal transduction by p53 class mediatorGO:004351850.709
positive regulation of macroautophagyGO:001623930.701
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.696
signal transduction involved in mitotic cell cycle checkpointGO:007241330.695
regulation of cellular response to stressGO:00801351590.692
negative regulation of protein modification processGO:00314001630.689
negative regulation of cellular protein metabolic processGO:00322692470.679
regulation of transferase activityGO:00513382630.677
response to antibioticGO:0046677110.675
negative regulation of protein metabolic processGO:00512482820.662
Human
double strand break repairGO:0006302480.659
regulation of cell cycle processGO:00105641600.647
Mouse
meiotic cell cycleGO:00513211220.634
skeletal system developmentGO:00015013560.630
protein ubiquitinationGO:00165671710.628
Mouse
cellular protein catabolic processGO:00442571550.612
regulation of cellular catabolic processGO:00313292420.610
protein localization to organelleGO:00333651850.604
regionalizationGO:00030023370.603
negative regulation of phosphate metabolic processGO:00459361840.602
appendage morphogenesisGO:00351071490.595
leukocyte differentiationGO:00025213420.583
positive regulation of cell deathGO:00109422240.582
negative regulation of phosphorus metabolic processGO:00105631840.569
negative regulation of cell cycle processGO:0010948690.556
intrinsic apoptotic signaling pathwayGO:00971931320.555
negative regulation of molecular functionGO:00440922580.547
homeostasis of number of cellsGO:00488722100.541
negative regulation of mitotic cell cycle phase transitionGO:1901991450.540
cell agingGO:0007569350.537
negative regulation of protein phosphorylationGO:00019331260.536
regulation of protein maturationGO:1903317960.534
positive regulation of protein phosphorylationGO:00019342420.532
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.529
negative regulation of intracellular signal transductionGO:19025321670.516
cell cycle g1 s phase transitionGO:0044843570.514
Mouse
regulation of cell cycle phase transitionGO:1901987770.514
Mouse
proteasomal protein catabolic processGO:0010498980.507
peptidyl amino acid modificationGO:00181933360.499
nuclear divisionGO:00002801580.497
amine metabolic processGO:0009308450.496
cell cycle arrestGO:0007050370.494
negative regulation of cellular amino acid metabolic processGO:004576300.493
mitotic cell cycle checkpointGO:0007093310.493
b cell activationGO:00421131610.488
glial cell apoptotic processGO:003434930.486
regulation of kinase activityGO:00435492490.486
regulation of cellular amine metabolic processGO:0033238200.485
regulation of response to dna damage stimulusGO:2001020340.485
release of cytochrome c from mitochondriaGO:0001836230.480
negative regulation of cellular amine metabolic processGO:003323910.480
ossificationGO:00015032160.477
regulation of apoptotic signaling pathwayGO:20012331970.458
dna damage response signal transduction by p53 class mediatorGO:0030330190.456
Human
regulation of protein localizationGO:00328802310.455
cellular amine metabolic processGO:0044106440.444
epithelial cell proliferationGO:00506731740.437
regulation of protein kinase activityGO:00458592320.435
ras protein signal transductionGO:0007265770.435
fibroblast proliferationGO:0048144350.434
regulation of proteolysisGO:00301621640.430
cellular response to ionizing radiationGO:0071479110.420
mitotic cell cycle arrestGO:007185040.419
cellular response to antibioticGO:007123640.418
positive regulation of proteolysisGO:0045862850.416
positive regulation of apoptotic signaling pathwayGO:2001235950.411
nucleotide excision repairGO:0006289130.410
peptidyl lysine modificationGO:0018205770.406
dna integrity checkpointGO:0031570280.406
negative regulation of transferase activityGO:0051348850.404
cellular ketone metabolic processGO:0042180840.402
response to oxygen levelsGO:0070482620.402
Human
protein catabolic processGO:00301632210.396
Human Mouse
protein localization to nucleusGO:00345041210.392
limb developmentGO:00601731660.391
dna damage checkpointGO:0000077260.387
negative regulation of cell cycle phase transitionGO:1901988480.385
regulation of mitotic cell cycleGO:00073461260.384
Mouse
negative regulation of proteolysisGO:0045861740.384
leukocyte proliferationGO:00706611720.382
regulation of cell cycle arrestGO:0071156120.382
cellular macromolecule catabolic processGO:00442652060.377
germ cell developmentGO:00072811850.377
negative regulation of map kinase activityGO:0043407340.375
reactive oxygen species metabolic processGO:0072593840.360
negative regulation of kinase activityGO:0033673810.356
skeletal muscle organ developmentGO:00605381630.355
negative regulation of leukocyte differentiationGO:1902106510.353
signal transduction involved in mitotic g1 dna damage checkpointGO:007243130.351
negative regulation of cell proliferationGO:00082852960.350
cellular senescenceGO:0090398110.350
negative regulation of immune system processGO:00026832090.347
dna replicationGO:0006260520.336
telomere cappingGO:001623340.326
negative regulation of protein maturationGO:1903318790.325
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.325
regulation of nucleocytoplasmic transportGO:0046822730.324
regulation of cellular ketone metabolic processGO:0010565660.323
cellular amino acid metabolic processGO:00065201030.320
regulation of reactive oxygen species metabolic processGO:2000377400.313
cellular response to radiationGO:0071478280.309
positive regulation of cellular amine metabolic processGO:003324050.309
positive regulation of chromatin modificationGO:1903310280.304
mitotic cell cycleGO:00002781950.304
Mouse
regulation of ossificationGO:00302781120.300
regulation of leukocyte apoptotic processGO:2000106560.297
regulation of chromatin organizationGO:1902275570.293
negative regulation of apoptotic signaling pathwayGO:20012341040.291
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.291
negative regulation of protein serine threonine kinase activityGO:0071901490.289
peptidyl serine modificationGO:0018209830.288
regulation of protein catabolic processGO:00421761080.284
Human
mitochondrion degradationGO:000042230.278
regulation of cell cycle g1 s phase transitionGO:1902806350.265
Mouse
hematopoietic progenitor cell differentiationGO:00022441430.262
embryonic limb morphogenesisGO:00303261260.259
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.257
positive regulation of g1 s transition of mitotic cell cycleGO:190008790.255
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.254
negative regulation of phosphatidylinositol 3 kinase activityGO:004355310.253
positive regulation of cell cycle phase transitionGO:1901989170.252
Mouse
positive regulation of cellular catabolic processGO:00313311480.251
apoptotic signaling pathwayGO:00971903060.251
negative regulation of growthGO:0045926990.251
regulation of hydrolase activityGO:00513362460.250
response to ionizing radiationGO:0010212420.249
stem cell differentiationGO:00488632680.237
lens development in camera type eyeGO:0002088620.237
mitochondrial dna repairGO:004350430.235
regulation of mapk cascadeGO:00434082480.235
response to endoplasmic reticulum stressGO:0034976530.232
negative regulation of intracellular protein transportGO:0090317270.232
signal transduction in response to dna damageGO:0042770210.231
Human
small gtpase mediated signal transductionGO:0007264970.230
stem cell developmentGO:00488642190.230
protein autophosphorylationGO:0046777610.230
stem cell maintenanceGO:00198271300.229
positive regulation of neuron deathGO:1901216280.226
methylationGO:00322591340.224
regulation of protein processingGO:0070613960.223
positive regulation of growthGO:00459271040.221
cell fate commitmentGO:00451652100.221
response to radiationGO:00093141650.220
axon guidanceGO:00074111410.215
positive regulation of kinase activityGO:00336741550.215
protein methylationGO:0006479810.214
female genitalia morphogenesisGO:004880730.214
cell divisionGO:00513011200.210
embryonic organ morphogenesisGO:00485622760.208
regulation of g1 s transition of mitotic cell cycleGO:2000045350.207
Mouse
positive regulation of keratinocyte proliferationGO:001083840.206
lymphocyte proliferationGO:00466511640.206
regulation of intracellular protein transportGO:0033157820.204
positive regulation of striated muscle cell apoptotic processGO:001066330.203
regulation of protein localization to nucleusGO:1900180600.201
regulation of proteasomal protein catabolic processGO:0061136460.201
macromolecule catabolic processGO:00090572810.201
Human Mouse
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activityGO:003816710.199
regulation of histone modificationGO:0031056560.198
neuron deathGO:00709971540.198
appendage developmentGO:00487361660.197
response to growth factorGO:00708481980.192
regulation of endopeptidase activityGO:0052548890.190
skeletal system morphogenesisGO:00487052030.189
negative regulation of mapk cascadeGO:0043409650.188
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.184
cytoplasmic transportGO:00164822340.184
cell type specific apoptotic processGO:00972852680.183
negative regulation of epithelial cell proliferationGO:0050680640.181
positive regulation of mitotic cell cycleGO:0045931410.180
Mouse
regulation of cellular protein catabolic processGO:1903362610.180
chemotaxisGO:00069352470.179
positive regulation of programmed cell deathGO:00430682180.179
positive regulation of organelle organizationGO:00106381280.179
response to reactive oxygen speciesGO:0000302560.178
negative regulation of response to dna damage stimulusGO:2001021100.178
bone developmentGO:00603481200.175
chromosome segregationGO:0007059480.175
apoptotic mitochondrial changesGO:0008637480.174
cellular response to growth factor stimulusGO:00713631970.174
central nervous system neuron differentiationGO:00219531620.169
histone modificationGO:00165701590.163
cellular response to x rayGO:007148120.160
programmed necrotic cell deathGO:0097300280.159
regulation of leukocyte proliferationGO:00706631210.158
positive regulation of cellular amino acid metabolic processGO:004576430.157
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.157
retina development in camera type eyeGO:00600411190.157
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.155
meiotic cell cycle processGO:1903046770.155
positive regulation of protein modification processGO:00314012990.155
positive regulation of peptidase activityGO:0010952490.153
regulation of fibroblast proliferationGO:0048145340.152
regulation of protein ubiquitinationGO:0031396520.152
regulation of epithelial cell proliferationGO:00506781410.152
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascadeGO:003816810.151
positive regulation of mitotic cell cycle phase transitionGO:1901992170.151
Mouse
regulation of neuron deathGO:19012141340.148
mitotic cell cycle processGO:19030471590.147
Mouse
negative regulation of cellular component organizationGO:00511291940.147
response to hypoxiaGO:0001666580.146
Human
regulation of leukocyte differentiationGO:19021051590.145
activation of cysteine type endopeptidase activityGO:0097202270.140
negative regulation of lymphocyte activationGO:0051250910.138
regulation of lymphocyte differentiationGO:00456191070.137
macroautophagyGO:0016236210.136
regulation of lymphocyte activationGO:00512492400.136
posttranscriptional regulation of gene expressionGO:00106081550.135
Human
regulation of chromatin modificationGO:1903308570.134
t cell differentiation in thymusGO:0033077770.134
erythrocyte differentiationGO:0030218880.132
positive regulation of bindingGO:0051099490.132
positive regulation of cell cycle processGO:0090068610.128
Mouse
cellular response to oxygen levelsGO:0071453200.127
Human
regulation of ion transportGO:00432692150.127
negative regulation of fibroblast proliferationGO:0048147140.127
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.126
striated muscle tissue developmentGO:00147062930.126
dna recombinationGO:0006310920.126
regulation of protein transportGO:00512231630.126
regulation of defense responseGO:00313472330.125
dendrite developmentGO:00163581150.123
dna conformation changeGO:0071103370.123
reciprocal dna recombinationGO:0035825160.122
dna biosynthetic processGO:0071897220.122
multicellular organism growthGO:00352641610.122
positive regulation of cardiac muscle cell apoptotic processGO:001066630.122
response to light stimulusGO:00094161350.121
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.121
myeloid cell apoptotic processGO:0033028220.121
negative regulation of cell cycle g1 s phase transitionGO:1902807180.121
cellular response to oxidative stressGO:0034599760.120
digestive tract developmentGO:00485651900.120
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.120
muscle cell differentiationGO:00426922610.120
mitochondrial membrane organizationGO:0007006260.119
telomere maintenance in response to dna damageGO:004324740.119
leukocyte homeostasisGO:0001776790.119
embryonic appendage morphogenesisGO:00351131260.118
regulation of intracellular transportGO:00323861590.118
positive regulation of muscle cell apoptotic processGO:001066160.116
regulation of autophagyGO:0010506300.116
gland developmentGO:00487323300.116
macromolecule deacylationGO:0098732370.116
lymphocyte homeostasisGO:0002260640.115
neuron projection guidanceGO:00974851410.114
regulation of cellular amino acid metabolic processGO:000652150.113
locomotory behaviorGO:00076261950.113
negative regulation of jun kinase activityGO:004350890.112
cellular response to organonitrogen compoundGO:00714171450.110
covalent chromatin modificationGO:00165691630.110
regulation of body fluid levelsGO:00508781620.108
regulation of neuron apoptotic processGO:00435231220.108
cation transportGO:00068123990.106
production of molecular mediator of immune responseGO:00024401030.105
oxidation reduction processGO:00551143420.102
cellular ion homeostasisGO:00068731650.102
embryonic skeletal system morphogenesisGO:0048704910.102
wound healingGO:00420601570.101
regulation of protein import into nucleusGO:0042306520.100
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.100
dna modificationGO:0006304500.098
myeloid cell homeostasisGO:00022621140.098
regulation of protein targetingGO:1903533610.097
organelle fissionGO:00482851700.097
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.097
chromatin organizationGO:00063252060.097
negative regulation of organelle organizationGO:0010639900.096
positive regulation of neuron apoptotic processGO:0043525250.095
mammary gland epithelium developmentGO:0061180650.094
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.094
t cell proliferationGO:00420981200.094
protection from non homologous end joining at telomereGO:003184840.093
renal system developmentGO:00720012250.093
reciprocal meiotic recombinationGO:0007131160.093
purine ribonucleotide metabolic processGO:00091502900.092
cellular response to light stimulusGO:0071482190.092
negative regulation of nuclear divisionGO:0051784190.092
immune response activating signal transductionGO:00027571160.092
developmental maturationGO:00217001930.091
nucleocytoplasmic transportGO:00069131390.091
generation of precursor metabolites and energyGO:00060911030.091
endothelial cell apoptotic processGO:007257790.090
negative regulation of cell divisionGO:0051782240.090
carbohydrate transportGO:0008643620.089
positive regulation of lymphocyte apoptotic processGO:0070230130.088
inflammatory responseGO:00069542440.088
cellular response to lipidGO:00713961450.088
neuron apoptotic processGO:00514021420.088
muscle cell apoptotic processGO:0010657180.088
t cell activationGO:00421102890.088
axonogenesisGO:00074092740.087
regulation of cellular component biogenesisGO:00440871810.087
notch signaling pathwayGO:0007219710.087
muscle tissue developmentGO:00605373080.086
cellular response to drugGO:0035690150.086
response to oxidative stressGO:00069791230.086
respiratory tube developmentGO:00303231670.086
response to acid chemicalGO:00011011110.085
skeletal muscle cell differentiationGO:0035914660.085
regulation of map kinase activityGO:00434051200.085
regulation of b cell activationGO:0050864810.085
jnk cascadeGO:0007254720.085
regulation of cellular component sizeGO:00325351210.085
somatic stem cell maintenanceGO:0035019470.084
regulation of chromosome organizationGO:0033044830.084
somatic cell dna recombinationGO:0016444510.084
positive regulation of nucleotide metabolic processGO:00459811140.083
cellular response to acid chemicalGO:0071229680.083
aromatic compound catabolic processGO:00194392860.083
negative regulation of reactive oxygen species metabolic processGO:2000378100.082
female gamete generationGO:0007292740.082
regulation of cysteine type endopeptidase activityGO:2000116650.082
regulation of peptidyl tyrosine phosphorylationGO:0050730930.081
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.080
positive regulation of cellular protein catabolic processGO:1903364340.080
signal transduction in absence of ligandGO:0038034550.080
regulation of sequence specific dna binding transcription factor activityGO:00510901060.080
sequestering of calcium ionGO:0051208180.079
b cell proliferationGO:0042100530.079
cation homeostasisGO:00550802120.079
regulation of establishment of protein localizationGO:00702011810.078
anatomical structure homeostasisGO:00602491450.078
stress activated protein kinase signaling cascadeGO:0031098810.077
camera type eye developmentGO:00430102660.077
dna packagingGO:0006323300.076
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.076
necrotic cell deathGO:0070265300.076
regulation of organelle organizationGO:00330432890.076
muscle cell developmentGO:00550011330.075
base excision repairGO:000628490.075
limb morphogenesisGO:00351081490.074
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.074
embryonic epithelial tube formationGO:00018381300.074
positive regulation of histone modificationGO:0031058280.073
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.073
membrane organizationGO:00610242450.073
dna endoreduplicationGO:004202340.072
response to organic cyclic compoundGO:00140701980.072
myeloid leukocyte differentiationGO:00025731190.072
t cell differentiationGO:00302171740.072
regulation of neuron differentiationGO:00456642810.071
columnar cuboidal epithelial cell differentiationGO:0002065820.071
response to drugGO:0042493750.071
wnt signaling pathwayGO:00160551880.070
neural tube developmentGO:00219151600.070
microtubule cytoskeleton organizationGO:00002261570.070
digestive system developmentGO:00551232000.070
branching morphogenesis of an epithelial tubeGO:00487541590.070
response to lipopolysaccharideGO:00324961280.069
regulation of protein modification by small protein conjugation or removalGO:1903320570.069
cellular response to external stimulusGO:0071496880.069
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.069
cellular divalent inorganic cation homeostasisGO:00725031270.069
mesoderm developmentGO:00074981000.068
positive regulation of cytokine biosynthetic processGO:0042108400.068
negative regulation of peptidase activityGO:0010466460.067
action potentialGO:0001508780.067
regulation of protein deacetylationGO:0090311170.067
male gamete generationGO:00482322850.067
kidney developmentGO:00018222130.066
positive regulation of cell cycle arrestGO:0071158100.066
multicellular organismal response to stressGO:0033555620.065
gene silencingGO:0016458380.065
intracellular protein transportGO:00068862040.064
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.064
histone deacetylationGO:0016575260.064
negative regulation of lipid kinase activityGO:009021910.063
purine ribonucleotide catabolic processGO:00091542080.063
cellular response to decreased oxygen levelsGO:0036294180.063
Human
pallium developmentGO:00215431200.063
protein targetingGO:00066051430.063
cellular response to hypoxiaGO:0071456170.062
Human
cellular response to biotic stimulusGO:0071216920.062
meiotic nuclear divisionGO:00071261150.062
myotube differentiationGO:00149021050.062
multicellular organismal homeostasisGO:00488711640.061
morphogenesis of embryonic epitheliumGO:00163311590.061
chromatin silencingGO:0006342150.061
nephron developmentGO:00720061090.061
negative regulation of wnt signaling pathwayGO:0030178730.060
b cell differentiationGO:0030183780.060
positive regulation of chromosome organizationGO:2001252330.060
cellular calcium ion homeostasisGO:00068741190.060
muscle fiber developmentGO:0048747760.060
positive regulation of nervous system developmentGO:00519622210.059
somatic recombination of immunoglobulin gene segmentsGO:0016447420.059
positive regulation of cell cycleGO:0045787920.059
Mouse
positive regulation of erk1 and erk2 cascadeGO:0070374470.059
myeloid cell differentiationGO:00300992330.059
response to transforming growth factor betaGO:0071559880.059
immune response regulating signaling pathwayGO:00027641250.058
negative regulation of nervous system developmentGO:00519611560.058
regulation of protein bindingGO:0043393600.058
syncytium formation by plasma membrane fusionGO:0000768420.058
neural tube closureGO:0001843900.058
negative regulation of intracellular transportGO:0032387380.057
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.057
protein modification by small protein removalGO:0070646210.057
second messenger mediated signalingGO:0019932730.057
regulation of muscle tissue developmentGO:1901861970.057
negative regulation of chromosome organizationGO:2001251300.057
organic cyclic compound catabolic processGO:19013612950.056
cell growthGO:00160491300.056
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.056
urogenital system developmentGO:00016552610.056
response to starvationGO:0042594650.056
regulation of t cell differentiationGO:0045580830.056
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.056
rna dependent dna replicationGO:000627830.056
cellular response to nitric oxideGO:007173240.055
regulation of angiogenesisGO:0045765810.055
cell cycle g2 m phase transitionGO:0044839200.055
purine ribonucleoside catabolic processGO:00461302050.055
oogenesisGO:0048477560.055
cardiac right ventricle formationGO:000321930.054
regulation of histone methylationGO:0031060300.054
metal ion homeostasisGO:00550651890.054
negative regulation of neuron apoptotic processGO:0043524920.054
skin developmentGO:00435882200.054
embryonic digit morphogenesisGO:0042733560.054
meiosis iGO:0007127600.054
regulation of muscle cell apoptotic processGO:0010660170.054
regulation of cytoplasmic transportGO:19036491120.054
phagocytosisGO:0006909660.054
cell maturationGO:00484691270.054
response to tumor necrosis factorGO:0034612260.053
cellular chemical homeostasisGO:00550822150.053
negative regulation of leukocyte proliferationGO:0070664460.053
positive regulation of myeloid cell differentiationGO:0045639430.053
positive regulation of smooth muscle cell migrationGO:001491140.053
bone morphogenesisGO:0060349780.053
negative regulation of cellular catabolic processGO:0031330470.053
regulation of peptidase activityGO:0052547960.052
negative regulation of lymphocyte proliferationGO:0050672450.052
regulation of nucleotide metabolic processGO:00061401690.052
regulation of multi organism processGO:00439001110.052
digestive tract morphogenesisGO:00485461470.051
protein importGO:00170381010.051
calcium ion homeostasisGO:00550741270.051
cellular response to extracellular stimulusGO:0031668810.051
mitochondrial transportGO:0006839360.051
ribonucleoside catabolic processGO:00424542060.051
cellular response to peptideGO:1901653920.050

Mdm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.686
disease of cellular proliferationDOID:1456600.686
organ system cancerDOID:005068600.686
immune system cancerDOID:006008300.297
hematologic cancerDOID:253100.297
breast cancerDOID:161200.115
thoracic cancerDOID:509300.115
gastrointestinal system cancerDOID:311900.081
liver carcinomaDOID:68600.081
liver cancerDOID:357100.081
large intestine cancerDOID:567200.074
colon cancerDOID:21900.074
intestinal cancerDOID:1015500.074
colorectal cancerDOID:925600.074