Mus musculus

0 known processes

Laptm4a

lysosomal-associated protein transmembrane 4A

(Aliases: LAPTM4,MTP,mKIAA0108,Mtrp,AA286466)

Laptm4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
endoplasmic reticulum tubular network organizationGO:007178610.152
l amino acid transportGO:0015807320.123
cation transportGO:00068123990.093
apoptotic signaling pathwayGO:00971903060.090
macromolecule catabolic processGO:00090572810.089
protein catabolic processGO:00301632210.085
intracellular protein transportGO:00068862040.082
positive regulation of cell deathGO:00109422240.075
anion transportGO:00068201770.074
carboxylic acid transportGO:00469421000.072
regulation of protein localizationGO:00328802310.071
organic anion transportGO:00157111370.069
cell adhesionGO:00071553290.066
organic acid transportGO:00158491010.061
positive regulation of apoptotic processGO:00430652170.058
negative regulation of protein metabolic processGO:00512482820.056
regulation of cellular amino acid metabolic processGO:000652150.056
positive regulation of programmed cell deathGO:00430682180.055
amine metabolic processGO:0009308450.053
cellular ketone metabolic processGO:0042180840.052
cellular amine metabolic processGO:0044106440.051
engulfment of apoptotic cellGO:004365230.051
small gtpase mediated signal transductionGO:0007264970.050
cytokine productionGO:00018163190.049
negative regulation of glycoprotein metabolic processGO:190301930.048
extracellular structure organizationGO:00430621480.046
immune effector processGO:00022523210.045
negative regulation of molecular functionGO:00440922580.044
nitrogen compound transportGO:00717052710.044
signal transduction in absence of ligandGO:0038034550.044
gonad developmentGO:00084061410.043
cellular component assembly involved in morphogenesisGO:00109271390.043
cellular amino acid metabolic processGO:00065201030.041
positive regulation of cellular amino acid metabolic processGO:004576430.039
transmission of nerve impulseGO:0019226760.039
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:190223730.037
microtubule based processGO:00070172360.037
proteolysis involved in cellular protein catabolic processGO:00516031470.037
regulation of cellular amine metabolic processGO:0033238200.037
action potentialGO:0001508780.036
regulation of protein serine threonine kinase activityGO:00719001570.036
negative regulation of protein processingGO:0010955790.036
regulation of polyamine transmembrane transportGO:190226750.035
negative regulation of cellular component organizationGO:00511291940.035
regulation of protein transportGO:00512231630.034
regulation of protein catabolic processGO:00421761080.034
nucleoside phosphate metabolic processGO:00067533380.034
neuronal action potentialGO:0019228540.034
endocytosisGO:00068971680.034
extrinsic apoptotic signaling pathwayGO:00971911260.033
negative regulation of cellular protein metabolic processGO:00322692470.033
transmembrane transportGO:00550854120.033
regulation of membrane potentialGO:00423911920.032
development of primary sexual characteristicsGO:00451371430.031
protein maturationGO:00516041760.031
regulation of cellular ketone metabolic processGO:0010565660.031
spermatogenesisGO:00072832840.031
positive regulation of cellular amine metabolic processGO:003324050.030
male gamete generationGO:00482322850.030
skeletal system developmentGO:00015013560.030
gland developmentGO:00487323300.029
regulation of acetylcholine secretion neurotransmissionGO:001405620.029
actin cytoskeleton organizationGO:00300362200.029
purine ribonucleotide catabolic processGO:00091542080.029
regulation of anatomical structure sizeGO:00900661780.028
g protein coupled receptor signaling pathwayGO:00071862430.028
amino acid transportGO:0006865610.028
regulation of neuron projection developmentGO:00109751690.028
myelinationGO:0042552740.028
mitochondrion distributionGO:004831140.028
cytoplasmic transportGO:00164822340.028
regulation of cellular response to stressGO:00801351590.028
positive regulation of macroautophagyGO:001623930.027
regulation of immunological synapse formationGO:200052020.027
regulation of neuron differentiationGO:00456642810.027
cell cell junction organizationGO:0045216720.027
extracellular matrix organizationGO:00301981470.027
multicellular organismal signalingGO:0035637910.027
cellular macromolecule catabolic processGO:00442652060.027
protein processingGO:00164851630.027
glycoprotein biosynthetic processGO:0009101890.027
regulation of lymphocyte activationGO:00512492400.027
regulation of hydrolase activityGO:00513362460.027
regulation of transferase activityGO:00513382630.026
wnt signaling pathwayGO:00160551880.026
cellular homeostasisGO:00197252400.026
circadian sleep wake cycle rem sleepGO:004274710.026
posttranscriptional regulation of gene expressionGO:00106081550.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
organelle fissionGO:00482851700.026
microglia developmentGO:001400520.025
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.025
regulation of protein stabilityGO:0031647520.025
cellular protein catabolic processGO:00442571550.025
cellular chemical homeostasisGO:00550822150.024
cell fate commitmentGO:00451652100.024
regulation of peptidase activityGO:0052547960.024
axon ensheathmentGO:0008366760.024
dna metabolic processGO:00062593030.023
serine transportGO:003232920.023
membrane organizationGO:00610242450.023
regulation of cell motilityGO:20001452360.023
regulation of vacuole organizationGO:004408840.023
regulation of cytokine productionGO:00018172660.023
peptidyl amino acid modificationGO:00181933360.022
regulation of mapk cascadeGO:00434082480.022
cation homeostasisGO:00550802120.022
muscle tissue developmentGO:00605373080.022
positive regulation of apoptotic signaling pathwayGO:2001235950.022
regulation of reactive oxygen species biosynthetic processGO:190342620.022
cell substrate adhesionGO:00315891300.022
germ cell developmentGO:00072811850.021
multi multicellular organism processGO:00447061090.021
phospholipid metabolic processGO:0006644870.021
modification dependent macromolecule catabolic processGO:00436321330.021
regulation of apoptotic signaling pathwayGO:20012331970.021
response to peptide hormoneGO:00434341270.021
oxidation reduction processGO:00551143420.021
leukocyte differentiationGO:00025213420.020
ossificationGO:00015032160.020
endomembrane system organizationGO:00102561470.020
cellularizationGO:000734910.020
membrane fusionGO:0061025380.020
carbohydrate derivative catabolic processGO:19011362310.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
innate immune responseGO:00450871570.020
cellular lipid metabolic processGO:00442553230.020
sensory perception of touchGO:005097520.020
mitotic cell cycleGO:00002781950.020
ion transmembrane transportGO:00342203610.020
organic cyclic compound catabolic processGO:19013612950.020
leukocyte mediated cytotoxicityGO:0001909620.020
response to oxidative stressGO:00069791230.020
ribonucleotide catabolic processGO:00092612080.020
exocyst localizationGO:005160120.020
regulation of protein processingGO:0070613960.019
multicellular organismal homeostasisGO:00488711640.019
cation transmembrane transportGO:00986552660.019
regulation of intracellular protein transportGO:0033157820.019
chemotaxisGO:00069352470.019
negative regulation of proteolysisGO:0045861740.019
striated muscle tissue developmentGO:00147062930.019
response to organic cyclic compoundGO:00140701980.019
microtubule cytoskeleton organizationGO:00002261570.019
positive regulation of nervous system developmentGO:00519622210.019
regulation of establishment of protein localizationGO:00702011810.019
myeloid cell differentiationGO:00300992330.018
cellular protein complex assemblyGO:00436231160.018
ensheathment of neuronsGO:0007272760.018
leukocyte mediated immunityGO:00024431740.018
hematopoietic progenitor cell differentiationGO:00022441430.018
purine nucleoside triphosphate catabolic processGO:00091462030.018
metal ion homeostasisGO:00550651890.018
male sex differentiationGO:00466611090.018
protein localization to organelleGO:00333651850.018
forebrain developmentGO:00309003020.018
mapk cascadeGO:00001652810.017
cellular nitrogen compound catabolic processGO:00442702800.017
amyloid precursor protein biosynthetic processGO:004298330.017
rho protein signal transductionGO:0007266320.017
glycerophospholipid metabolic processGO:0006650710.017
purine containing compound metabolic processGO:00725213110.017
guanosine containing compound metabolic processGO:19010681440.017
nucleotide metabolic processGO:00091173320.017
regulation of protein maturationGO:1903317960.017
negative regulation of cell developmentGO:00107211690.017
organic hydroxy compound metabolic processGO:19016152030.017
actin polymerization or depolymerizationGO:0008154540.017
regulation of vesicle mediated transportGO:00606271390.017
mrna metabolic processGO:0016071840.017
regulation of secretionGO:00510462740.017
forebrain cell migrationGO:0021885580.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
cleavage furrow formationGO:003608920.016
regulation of response to woundingGO:19030341890.016
positive regulation of protein serine threonine kinase activityGO:00719021060.016
protein palmitoylationGO:0018345140.016
acetylcholine transportGO:001587020.016
cellular response to hormone stimulusGO:00328701500.016
midgut developmentGO:000749440.016
cell junction maintenanceGO:003433140.016
lateral inhibitionGO:004633110.016
nuclear divisionGO:00002801580.016
production of molecular mediator of immune responseGO:00024401030.016
regulation of hormone levelsGO:00108172110.016
b cell activation involved in immune responseGO:0002312500.016
regulation of cellular component sizeGO:00325351210.016
ribonucleotide metabolic processGO:00092592910.016
positive regulation of protein phosphorylationGO:00019342420.016
hormone metabolic processGO:0042445860.016
positive regulation of lymphocyte activationGO:00512511400.016
regulation of organelle organizationGO:00330432890.016
embryonic organ morphogenesisGO:00485622760.016
angiogenesisGO:00015252010.016
ribonucleoside metabolic processGO:00091192450.015
regulation of secretion by cellGO:19035302490.015
maintenance of locationGO:0051235890.015
response to nutrient levelsGO:00316671090.015
response to inorganic substanceGO:0010035960.015
glycoprotein metabolic processGO:00091001160.015
copper ion homeostasisGO:005507090.015
inflammatory responseGO:00069542440.015
muscle cell differentiationGO:00426922610.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
reactive oxygen species biosynthetic processGO:190340980.015
negative regulation of protein maturationGO:1903318790.015
camera type eye developmentGO:00430102660.015
aromatic compound catabolic processGO:00194392860.015
microglia differentiationGO:001400420.015
cellular response to organonitrogen compoundGO:00714171450.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
regulation of lipid metabolic processGO:00192161180.015
protein ubiquitinationGO:00165671710.015
ribose phosphate metabolic processGO:00196932910.015
leukocyte activation involved in immune responseGO:00023661260.015
negative regulation of phosphorus metabolic processGO:00105631840.015
regulation of cell cycleGO:00517262810.015
lymphocyte activation involved in immune responseGO:0002285930.015
actin filament polymerizationGO:0030041440.015
positive regulation of mapk cascadeGO:00434101700.015
response to organonitrogen compoundGO:00102432460.015
t cell activationGO:00421102890.015
endoplasmic reticulum organizationGO:0007029100.014
canonical wnt signaling pathwayGO:00600701300.014
response to peptideGO:19016521360.014
monocarboxylic acid metabolic processGO:00327871910.014
fibrinolysisGO:004273030.014
digestive tract developmentGO:00485651900.014
divalent inorganic cation transportGO:00725111780.014
directional locomotionGO:003305830.014
heterocycle catabolic processGO:00467002800.014
sensory organ morphogenesisGO:00905962420.014
small molecule biosynthetic processGO:00442831320.014
golgi localizationGO:005164540.014
carbohydrate homeostasisGO:00335001280.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
regulation of mitotic cell cycleGO:00073461260.014
regulation of cell migrationGO:00303342190.014
divalent metal ion transportGO:00708381720.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
calcium ion transportGO:00068161590.014
regulation of transmembrane transportGO:00347621280.014
digestive system developmentGO:00551232000.013
regulation of cell adhesionGO:00301551540.013
nucleoside triphosphate metabolic processGO:00091412300.013
antigen processing and presentationGO:0019882470.013
transition metal ion homeostasisGO:0055076540.013
regulation of cell cycle processGO:00105641600.013
cellular response to peptideGO:1901653920.013
gtp metabolic processGO:00460391440.013
cellular response to extracellular stimulusGO:0031668810.013
glycerolipid metabolic processGO:00464861220.013
compound eye developmentGO:004874910.013
regulation of lamellipodium assemblyGO:001059130.013
regulation of leukocyte mediated cytotoxicityGO:0001910380.013
response to extracellular stimulusGO:00099911270.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
protein localization to plasma membraneGO:0072659570.013
lateral line system developmentGO:004892510.013
purine nucleotide metabolic processGO:00061633020.013
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.013
telencephalon developmentGO:00215371860.013
regulation of lymphocyte mediated immunityGO:0002706840.013
response to water deprivationGO:000941410.013
inter male aggressive behaviorGO:000212130.013
cellular response to external stimulusGO:0071496880.013
embryonic olfactory bulb interneuron precursor migrationGO:002183120.013
regulation of cell activationGO:00508652890.013
rna processingGO:00063961050.013
defense response to other organismGO:00985421970.013
response to molecule of bacterial originGO:00022371430.013
regulation of t cell activationGO:00508631700.013
oocyte anterior posterior axis specificationGO:000731420.013
acetylcholine secretion neurotransmissionGO:001405520.013
positive regulation of secretion by cellGO:19035321140.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
cellular response to dna damage stimulusGO:00069742070.013
positive regulation of cell adhesionGO:0045785800.013
nucleoside metabolic processGO:00091162460.013
glial cell differentiationGO:00100011310.012
stem cell differentiationGO:00488632680.012
maintenance of epithelial cell apical basal polarityGO:004519920.012
nucleobase containing small molecule metabolic processGO:00550863520.012
gliogenesisGO:00420631410.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
regulation of cellular catabolic processGO:00313292420.012
inorganic ion transmembrane transportGO:00986602340.012
actin filament organizationGO:00070151130.012
lipid localizationGO:00108761260.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
carbohydrate derivative biosynthetic processGO:19011371830.012
ras protein signal transductionGO:0007265770.012
developmental maturationGO:00217001930.012
positive regulation of protein modification processGO:00314012990.012
regulation of amyloid precursor protein biosynthetic processGO:004298430.012
regulation of endocytosisGO:0030100690.012
cardiac muscle tissue developmentGO:00487381300.012
regulation of defense responseGO:00313472330.012
positive regulation of podosome assemblyGO:007180330.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
adaptive immune responseGO:00022501550.012
lipid biosynthetic processGO:00086101790.012
vacuole organizationGO:0007033380.012
cellular metal ion homeostasisGO:00068751510.012
reactive nitrogen species metabolic processGO:200105700.012
male anatomical structure morphogenesisGO:009059840.012
lymphocyte proliferationGO:00466511640.012
positive regulation of secretionGO:00510471300.012
defense response to bacteriumGO:00427421190.012
purine containing compound catabolic processGO:00725232130.012
lymphocyte differentiationGO:00300982420.012
myeloid leukocyte differentiationGO:00025731190.012
rna splicingGO:0008380540.012
organonitrogen compound catabolic processGO:19015652640.012
peptidyl tyrosine modificationGO:00182121450.012
circulatory system processGO:00030131970.012
cell recognitionGO:0008037830.012
protein targetingGO:00066051430.012
mitotic nuclear divisionGO:0007067480.012
reactive oxygen species metabolic processGO:0072593840.012
glycosyl compound metabolic processGO:19016572460.012
cellular response to peptide hormone stimulusGO:0071375920.012
water soluble vitamin biosynthetic processGO:004236430.012
regulation of body fluid levelsGO:00508781620.012
inorganic cation transmembrane transportGO:00986622070.012
ear developmentGO:00435832000.012
connective tissue developmentGO:00614481790.012
pole plasm assemblyGO:000731520.011
male genitalia morphogenesisGO:004880840.011
organic acid biosynthetic processGO:0016053860.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of immune effector processGO:00026991070.011
negative regulation of cell proliferationGO:00082852960.011
negative regulation of phosphorylationGO:00423261660.011
dorsal ventral axon guidanceGO:003356330.011
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:1902235110.011
l glutamate transportGO:0015813160.011
establishment or maintenance of cell polarityGO:0007163860.011
regulation of interferon gamma productionGO:0032649570.011
retrograde transport endosome to golgiGO:004214720.011
regulation of proteolysisGO:00301621640.011
regulation of ossificationGO:00302781120.011
positive regulation of protein kinase activityGO:00458601440.011
oogenesisGO:0048477560.011
positive regulation of cell cycleGO:0045787920.011
nucleotide catabolic processGO:00091662170.011
regulation of endopeptidase activityGO:0052548890.011
locomotory behaviorGO:00076261950.011
forebrain radial glial cell differentiationGO:002186140.011
ameboidal type cell migrationGO:00016671280.011
acidic amino acid transportGO:0015800160.011
transition metal ion transportGO:0000041380.011
neutral amino acid transportGO:0015804130.011
organonitrogen compound biosynthetic processGO:19015661920.011
regulation of ion transportGO:00432692150.011
wound healingGO:00420601570.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
regulation of leukocyte mediated immunityGO:00027031040.011
negative regulation of organelle organizationGO:0010639900.011
establishment or maintenance of actin cytoskeleton polarityGO:003095010.011
negative regulation of hydrolase activityGO:0051346710.011
protein modification by small protein conjugation or removalGO:00706472070.011
regulation of intracellular transportGO:00323861590.011
nuclear transportGO:00511691390.011
lymphocyte mediated immunityGO:00024491390.011
protein modification by small protein conjugationGO:00324461870.011
skeletal muscle myosin thick filament assemblyGO:003024110.011
calcium ion homeostasisGO:00550741270.011
cellular divalent inorganic cation homeostasisGO:00725031270.010
regulation of kinase activityGO:00435492490.010
regulation of wnt signaling pathwayGO:00301111230.010
i kappab kinase nf kappab signalingGO:0007249850.010
striated muscle myosin thick filament assemblyGO:007168810.010
b cell activationGO:00421131610.010
negative regulation of cell projection organizationGO:0031345560.010
blood circulationGO:00080151950.010
protein localization to cell junctionGO:190241430.010
cell chemotaxisGO:0060326810.010
neuron apoptotic processGO:00514021420.010
protein secretionGO:00093061110.010
cerebral cortex developmentGO:0021987860.010
mrna processingGO:0006397630.010
cytokinetic processGO:003250620.010
regulation of leukocyte proliferationGO:00706631210.010
negative regulation of immune system processGO:00026832090.010
spindle assembly involved in mitosisGO:009030740.010
nucleoside catabolic processGO:00091642060.010
regulation of dna replicationGO:0006275170.010
plasma membrane organizationGO:0007009900.010
placenta developmentGO:00018901400.010
positive regulation of cell developmentGO:00107202370.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
organophosphate catabolic processGO:00464342320.010
positive regulation of cell killingGO:0031343330.010
t cell proliferationGO:00420981200.010
regulation of mrna metabolic processGO:1903311430.010
negative regulation of amyloid precursor protein biosynthetic processGO:004298520.010

Laptm4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.054
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
sensory system diseaseDOID:005015500.030
eye and adnexa diseaseDOID:149200.030
acquired metabolic diseaseDOID:006015800.028
musculoskeletal system diseaseDOID:1700.027
connective tissue diseaseDOID:6500.027
retinal diseaseDOID:567900.023
eye diseaseDOID:561400.023
retinal degenerationDOID:846600.023
amyloidosisDOID:912000.023
inherited metabolic disorderDOID:65500.022
bone diseaseDOID:008000100.021
bone development diseaseDOID:008000600.014
immune system diseaseDOID:291400.013
central nervous system diseaseDOID:33100.012
hematopoietic system diseaseDOID:7400.012