Mus musculus

134 known processes

Rps6ka2

ribosomal protein S6 kinase, polypeptide 2

(Aliases: pp90rsk,D17Wsu134e,Rps6ka-rs1,p90rsk,90kDa,Rsk3)

Rps6ka2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine containing compound metabolic processGO:00725213110.122
ras protein signal transductionGO:0007265770.104
Fly
purine nucleotide metabolic processGO:00061633020.101
cellular amino acid metabolic processGO:00065201030.098
ribose phosphate metabolic processGO:00196932910.094
nucleotide metabolic processGO:00091173320.093
nucleoside phosphate metabolic processGO:00067533380.085
organic cyclic compound catabolic processGO:19013612950.077
purine ribonucleotide metabolic processGO:00091502900.076
regulation of cellular catabolic processGO:00313292420.074
nucleobase containing small molecule metabolic processGO:00550863520.071
ion transmembrane transportGO:00342203610.063
synaptic transmissionGO:00072683290.061
transmembrane transportGO:00550854120.060
cellular homeostasisGO:00197252400.060
axonogenesisGO:00074092740.058
organonitrogen compound catabolic processGO:19015652640.058
ribonucleoside triphosphate catabolic processGO:00092031990.057
locomotory behaviorGO:00076261950.056
Fly
nucleoside catabolic processGO:00091642060.056
nitrogen compound transportGO:00717052710.055
nucleoside phosphate catabolic processGO:19012922220.054
purine nucleoside catabolic processGO:00061522050.054
ribonucleoside metabolic processGO:00091192450.053
purine containing compound catabolic processGO:00725232130.052
carbohydrate derivative catabolic processGO:19011362310.052
aromatic compound catabolic processGO:00194392860.052
regulation of hydrolase activityGO:00513362460.052
purine ribonucleoside metabolic processGO:00461282410.051
purine nucleotide catabolic processGO:00061952110.050
guanosine containing compound metabolic processGO:19010681440.050
purine ribonucleotide catabolic processGO:00091542080.050
cation transportGO:00068123990.049
rho protein signal transductionGO:0007266320.049
small gtpase mediated signal transductionGO:0007264970.049
Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.048
purine nucleoside metabolic processGO:00422782410.048
nucleoside metabolic processGO:00091162460.048
purine nucleoside triphosphate catabolic processGO:00091462030.047
cellular amine metabolic processGO:0044106440.047
mapk cascadeGO:00001652810.046
Mouse
protein localization to membraneGO:00726571080.046
glycosyl compound catabolic processGO:19016582060.046
chemotaxisGO:00069352470.046
divalent inorganic cation transportGO:00725111780.045
cellular nitrogen compound catabolic processGO:00442702800.045
calcium ion transportGO:00068161590.044
purine ribonucleoside triphosphate catabolic processGO:00092071990.044
organophosphate catabolic processGO:00464342320.043
oxidation reduction processGO:00551143420.042
organic anion transportGO:00157111370.042
apoptotic signaling pathwayGO:00971903060.041
Mouse
anion transportGO:00068201770.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.041
purine nucleoside triphosphate metabolic processGO:00091442260.041
heterocycle catabolic processGO:00467002800.041
guanosine containing compound catabolic processGO:19010691440.041
regulation of hormone levelsGO:00108172110.040
cation transmembrane transportGO:00986552660.040
regulation of cellular amine metabolic processGO:0033238200.040
cellular ketone metabolic processGO:0042180840.039
negative regulation of molecular functionGO:00440922580.038
cell growthGO:00160491300.038
regulation of purine nucleotide metabolic processGO:19005421690.038
macromolecule catabolic processGO:00090572810.038
ribonucleoside triphosphate metabolic processGO:00091992200.037
glycosyl compound metabolic processGO:19016572460.037
ribonucleotide metabolic processGO:00092592910.036
regulation of gtp catabolic processGO:00331241130.036
regulation of nucleoside metabolic processGO:00091181300.036
ribonucleoside catabolic processGO:00424542060.036
positive regulation of nervous system developmentGO:00519622210.036
dephosphorylationGO:00163111290.035
protein catabolic processGO:00301632210.035
endomembrane system organizationGO:00102561470.034
gtp catabolic processGO:00061841430.034
peptidyl amino acid modificationGO:00181933360.034
intracellular protein transportGO:00068862040.034
Fly
organelle assemblyGO:00709251770.034
positive regulation of cell developmentGO:00107202370.033
regulation of cellular ketone metabolic processGO:0010565660.033
membrane organizationGO:00610242450.033
carbohydrate metabolic processGO:00059752300.033
nucleoside triphosphate catabolic processGO:00091432050.033
regulation of purine nucleotide catabolic processGO:00331211220.032
cellular chemical homeostasisGO:00550822150.032
regulation of cellular amino acid metabolic processGO:000652150.032
regulation of synaptic growth at neuromuscular junctionGO:000858240.032
regulation of nucleotide metabolic processGO:00061401690.032
regulation of secretionGO:00510462740.032
regulation of ion transportGO:00432692150.032
muscle system processGO:00030121410.032
divalent metal ion transportGO:00708381720.031
gtp metabolic processGO:00460391440.030
organonitrogen compound biosynthetic processGO:19015661920.030
response to organonitrogen compoundGO:00102432460.030
regulation of system processGO:00440572000.030
regulation of apoptotic signaling pathwayGO:20012331970.030
Mouse
cell adhesionGO:00071553290.030
response to oxidative stressGO:00069791230.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
regulation of ras protein signal transductionGO:00465781140.029
Fly
protein localization to organelleGO:00333651850.029
Fly
response to radiationGO:00093141650.029
organic acid transportGO:00158491010.028
positive regulation of hydrolase activityGO:00513451480.028
response to light stimulusGO:00094161350.028
negative regulation of intracellular signal transductionGO:19025321670.028
Mouse Fly
inorganic ion transmembrane transportGO:00986602340.028
regulation of cell growthGO:0001558910.028
plasma membrane organizationGO:0007009900.027
regulation of anatomical structure sizeGO:00900661780.027
g protein coupled receptor signaling pathwayGO:00071862430.027
protein targetingGO:00066051430.027
Fly
ribonucleotide catabolic processGO:00092612080.027
developmental maturationGO:00217001930.026
amine metabolic processGO:0009308450.026
purine ribonucleoside catabolic processGO:00461302050.026
regulation of mapk cascadeGO:00434082480.026
Mouse
negative regulation of cellular amine metabolic processGO:003323910.026
proteolysis involved in cellular protein catabolic processGO:00516031470.026
inorganic cation transmembrane transportGO:00986622070.026
ossificationGO:00015032160.026
regulation of proteolysisGO:00301621640.026
male gamete generationGO:00482322850.025
retina development in camera type eyeGO:00600411190.025
nucleoside triphosphate metabolic processGO:00091412300.025
negative regulation of cell proliferationGO:00082852960.025
Human
alpha amino acid metabolic processGO:1901605590.025
response to molecule of bacterial originGO:00022371430.025
Mouse
cellular response to organonitrogen compoundGO:00714171450.025
sensory perceptionGO:00076002450.024
regulation of ion transmembrane transportGO:00347651190.024
organelle localizationGO:00516401790.024
regulation of cell projection organizationGO:00313442060.024
nucleotide catabolic processGO:00091662170.024
cation homeostasisGO:00550802120.024
regulation of protein localizationGO:00328802310.024
Fly
positive regulation of cell deathGO:00109422240.024
Human
negative regulation of phosphorus metabolic processGO:00105631840.024
Mouse
regulation of protein kinase activityGO:00458592320.024
regulation of secretion by cellGO:19035302490.024
regulation of neuron differentiationGO:00456642810.023
Fly
muscle contractionGO:00069361010.023
carboxylic acid transportGO:00469421000.023
positive regulation of protein modification processGO:00314012990.023
multicellular organism growthGO:00352641610.023
establishment of organelle localizationGO:00516561220.023
muscle tissue developmentGO:00605373080.023
cytoplasmic transportGO:00164822340.023
Fly
response to organic cyclic compoundGO:00140701980.022
response to lipopolysaccharideGO:00324961280.022
Mouse
regulation of rho protein signal transductionGO:0035023710.022
epithelial tube morphogenesisGO:00605623030.022
posttranscriptional regulation of gene expressionGO:00106081550.022
positive regulation of purine nucleotide metabolic processGO:19005441140.022
regulation of nucleotide catabolic processGO:00308111220.021
neuron projection guidanceGO:00974851410.021
camera type eye developmentGO:00430102660.021
maintenance of locationGO:0051235890.021
nucleocytoplasmic transportGO:00069131390.021
Fly
regulation of cellular response to stressGO:00801351590.021
positive regulation of purine nucleotide catabolic processGO:0033123880.021
cellular ion homeostasisGO:00068731650.021
homeostasis of number of cellsGO:00488722100.021
regulation of ras gtpase activityGO:0032318880.021
regulation of metal ion transportGO:00109591060.021
negative regulation of protein metabolic processGO:00512482820.021
regionalizationGO:00030023370.021
Fly
regulation of bindingGO:00510981110.020
regulation of cell cycleGO:00517262810.020
cellular lipid metabolic processGO:00442553230.020
carbohydrate derivative biosynthetic processGO:19011371830.020
ubiquitin dependent protein catabolic processGO:00065111290.020
regulation of cell motilityGO:20001452360.020
establishment of vesicle localizationGO:0051650810.020
regulation of organelle organizationGO:00330432890.020
microtubule based processGO:00070172360.020
blood vessel morphogenesisGO:00485142850.020
striated muscle tissue developmentGO:00147062930.020
positive regulation of cellular amine metabolic processGO:003324050.020
reactive oxygen species metabolic processGO:0072593840.019
positive regulation of nucleotide metabolic processGO:00459811140.019
regulation of ion transmembrane transporter activityGO:0032412540.019
negative regulation of protein phosphorylationGO:00019331260.019
regulation of cellular component biogenesisGO:00440871810.019
response to peptideGO:19016521360.019
cellular macromolecule catabolic processGO:00442652060.019
lipid localizationGO:00108761260.019
skeletal system developmentGO:00015013560.019
regulation of transmembrane transportGO:00347621280.019
blood circulationGO:00080151950.019
hormone secretionGO:00468791280.019
response to insulinGO:00328681000.019
positive regulation of cell projection organizationGO:0031346950.018
metal ion homeostasisGO:00550651890.018
retina morphogenesis in camera type eyeGO:0060042450.018
positive regulation of protein phosphorylationGO:00019342420.018
skin developmentGO:00435882200.018
protein modification by small protein conjugationGO:00324461870.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
rhythmic processGO:00485111740.018
Fly
mitochondrion transport along microtubuleGO:004749730.018
mitotic cell cycle processGO:19030471590.018
response to peptide hormoneGO:00434341270.018
protein localization to plasma membraneGO:0072659570.018
fertilizationGO:00095661270.018
microtubule based transportGO:0010970500.018
regulation of neurotransmitter levelsGO:0001505870.018
spermatogenesisGO:00072832840.018
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.017
modification dependent protein catabolic processGO:00199411330.017
regulation of transporter activityGO:0032409570.017
cellular response to biotic stimulusGO:0071216920.017
sensory organ morphogenesisGO:00905962420.017
Fly
regulation of transferase activityGO:00513382630.017
organic hydroxy compound metabolic processGO:19016152030.017
regulation of vasculature developmentGO:1901342880.017
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.017
cellular protein catabolic processGO:00442571550.017
response to growth factorGO:00708481980.017
cellular carbohydrate metabolic processGO:00442621190.017
protein processingGO:00164851630.017
multicellular organismal homeostasisGO:00488711640.017
adult behaviorGO:00305341350.017
positive regulation of nucleoside metabolic processGO:0045979910.016
amino acid transportGO:0006865610.016
negative regulation of cellular component organizationGO:00511291940.016
regulation of endopeptidase activityGO:0052548890.016
sensory perception of mechanical stimulusGO:00509541070.016
positive regulation of cellular catabolic processGO:00313311480.016
positive regulation of neuron differentiationGO:00456661410.016
actin cytoskeleton organizationGO:00300362200.016
positive regulation of nucleotide catabolic processGO:0030813880.016
monocarboxylic acid metabolic processGO:00327871910.016
anatomical structure homeostasisGO:00602491450.016
adult locomotory behaviorGO:0008344910.016
regulation of axon extensionGO:0030516430.016
sequestering of calcium ionGO:0051208180.016
establishment of mitochondrion localizationGO:005165440.016
tube formationGO:00351481400.016
amide transportGO:00428861380.016
peptide transportGO:00158331330.016
reactive oxygen species biosynthetic processGO:190340980.016
positive regulation of gtp catabolic processGO:0033126850.016
developmental growth involved in morphogenesisGO:00605601380.016
microtubule based movementGO:0007018840.016
negative regulation of apoptotic signaling pathwayGO:20012341040.016
Mouse
calcium ion homeostasisGO:00550741270.016
cell type specific apoptotic processGO:00972852680.016
appendage developmentGO:00487361660.015
Fly
regulation of muscle system processGO:0090257800.015
striated muscle contractionGO:0006941450.015
single organism cell adhesionGO:00986021560.015
regulation of neuron projection developmentGO:00109751690.015
muscle cell differentiationGO:00426922610.015
glucose homeostasisGO:00425931280.015
inflammatory responseGO:00069542440.015
single organismal cell cell adhesionGO:00163371310.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
positive regulation of programmed cell deathGO:00430682180.015
Human
cellular component assembly involved in morphogenesisGO:00109271390.015
response to oxygen levelsGO:0070482620.015
neuron migrationGO:00017641220.015
establishment or maintenance of cytoskeleton polarityGO:003095220.015
positive regulation of apoptotic processGO:00430652170.015
Human
protein hydroxylationGO:001812640.015
calcium ion transmembrane transportGO:0070588850.015
engulfment of apoptotic cellGO:004365230.015
negative regulation of phosphate metabolic processGO:00459361840.015
Mouse
connective tissue developmentGO:00614481790.015
dna metabolic processGO:00062593030.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
cellular metal ion homeostasisGO:00068751510.015
positive regulation of neuron projection developmentGO:0010976790.015
vesicle localizationGO:0051648860.015
histone modificationGO:00165701590.015
cellular response to cytokine stimulusGO:00713451890.015
cellular protein complex assemblyGO:00436231160.015
regulation of multi organism processGO:00439001110.014
negative regulation of cellular protein metabolic processGO:00322692470.014
chromatin organizationGO:00063252060.014
divalent inorganic cation homeostasisGO:00725071380.014
protein modification by small protein conjugation or removalGO:00706472070.014
spermatid differentiationGO:00485151150.014
single fertilizationGO:0007338820.014
oocyte constructionGO:000730820.014
myosin filament assemblyGO:003103420.014
cellular response to lipidGO:00713961450.014
germ cell developmentGO:00072811850.014
cognitionGO:00508901490.014
Fly
action potentialGO:0001508780.014
regulation of homeostatic processGO:00328441820.014
glycerolipid metabolic processGO:00464861220.014
transmission of nerve impulseGO:0019226760.014
compound eye developmentGO:004874910.014
Fly
striated muscle myosin thick filament assemblyGO:007168810.014
retrograde transport endosome to golgiGO:004214720.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
positive regulation of ras gtpase activityGO:0032320650.014
cellular response to hormone stimulusGO:00328701500.014
maternal determination of anterior posterior axis embryoGO:000835820.014
chromatin modificationGO:00165681870.014
tissue homeostasisGO:00018941150.014
negative regulation of growthGO:0045926990.014
mitotic cell cycleGO:00002781950.014
rac protein signal transductionGO:0016601130.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
oocyte axis specificationGO:000730920.014
negative regulation of protein modification processGO:00314001630.014
cellular calcium ion homeostasisGO:00068741190.014
sensory perception of soundGO:0007605970.014
regulation of calcium ion transportGO:0051924690.014
regulation of defense responseGO:00313472330.014
Mouse
modification dependent macromolecule catabolic processGO:00436321330.014
nuclear transportGO:00511691390.014
Fly
negative regulation of cell growthGO:0030308440.013
carbohydrate homeostasisGO:00335001280.013
regulation of establishment of protein localizationGO:00702011810.013
Fly
negative regulation of cellular amino acid metabolic processGO:004576300.013
intracellular mrna localizationGO:000829840.013
skeletal system morphogenesisGO:00487052030.013
visual perceptionGO:0007601520.013
embryonic organ morphogenesisGO:00485622760.013
regulation of body fluid levelsGO:00508781620.013
positive regulation of necrotic cell deathGO:001094010.013
peptide hormone secretionGO:00300721090.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
regulation of cytoskeleton organizationGO:00514931220.013
extracellular matrix organizationGO:00301981470.013
myosin filament organizationGO:003103330.013
cellular response to peptide hormone stimulusGO:0071375920.013
lipid transportGO:0006869980.013
regulation of protein serine threonine kinase activityGO:00719001570.013
sympathetic neuron projection extensionGO:009749040.013
heart contractionGO:0060047930.013
regulation of extent of cell growthGO:0061387520.013
synapse organizationGO:00508081250.013
Fly
circulatory system processGO:00030131970.013
lipid biosynthetic processGO:00086101790.013
wound healingGO:00420601570.013
cellular response to insulin stimulusGO:0032869780.013
gonadotrophin releasing hormone neuronal migration to the hypothalamusGO:002182830.013
gland developmentGO:00487323300.013
regulation of cytoplasmic transportGO:19036491120.013
Fly
regulation of cell adhesionGO:00301551540.013
leukocyte differentiationGO:00025213420.013
carboxylic acid biosynthetic processGO:0046394860.012
cellular modified amino acid metabolic processGO:0006575630.012
extracellular structure organizationGO:00430621480.012
sulfur compound metabolic processGO:00067901000.012
golgi to endosome transportGO:000689530.012
regulation of cell migrationGO:00303342190.012
regulation of kinase activityGO:00435492490.012
establishment or maintenance of cell polarityGO:0007163860.012
neuromuscular processGO:0050905990.012
nucleotide biosynthetic processGO:0009165780.012
morphogenesis of a branching epitheliumGO:00611381930.012
spermatid developmentGO:00072861080.012
hematopoietic progenitor cell differentiationGO:00022441430.012
exocytosisGO:00068871210.012
mitotic cytokinesisGO:000028140.012
protein localization to nucleusGO:00345041210.012
Fly
regulation of cellular component sizeGO:00325351210.012
cell divisionGO:00513011200.012
proteasomal protein catabolic processGO:0010498980.012
cellular response to lipopolysaccharideGO:0071222770.012
asymmetric neuroblast divisionGO:005505910.012
monocarboxylic acid transportGO:0015718440.012
regulation of cell activationGO:00508652890.012
mitochondrion distributionGO:004831140.011
t cell activationGO:00421102890.011
negative regulation of synapse assemblyGO:005196430.011
establishment of protein localization to membraneGO:0090150540.011
heart morphogenesisGO:00030071780.011
positive regulation of gtpase activityGO:0043547850.011
regulation of t cell activationGO:00508631700.011
relaxation of muscleGO:0090075180.011
dendrite developmentGO:00163581150.011
axon cargo transportGO:0008088330.011
cellular response to peptideGO:1901653920.011
myotube differentiationGO:00149021050.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
protein ubiquitinationGO:00165671710.011
cellular response to molecule of bacterial originGO:0071219830.011
negative regulation of protein kinase activity by regulation of protein phosphorylationGO:004438720.011
synaptic vesicle transportGO:0048489570.011
peptidyl proline hydroxylationGO:001951130.011
negative regulation of kinase activityGO:0033673810.011
regulation of reproductive processGO:2000241660.011
synaptic vesicle localizationGO:0097479590.011
regulation of hormone secretionGO:0046883880.011
cellular response to oxidative stressGO:0034599760.011
regulation of protein catabolic processGO:00421761080.011
positive regulation of proteolysisGO:0045862850.011
macromolecule methylationGO:00434141200.011
generation of precursor metabolites and energyGO:00060911030.011
peptide secretionGO:00027901140.011
regulation of intracellular transportGO:00323861590.011
Fly
regulation of synaptic plasticityGO:0048167870.011
lymphocyte differentiationGO:00300982420.011
sodium ion transportGO:0006814730.011
eye photoreceptor cell differentiationGO:0001754410.011
mitochondrion organizationGO:00070051340.011
placenta developmentGO:00018901400.011
nuclear importGO:0051170950.011
Fly
regulation of cell cycle processGO:00105641600.011
regulation of peptidase activityGO:0052547960.011
negative regulation of phosphorylationGO:00423261660.011
Mouse
neural tube closureGO:0001843900.011
sensory perception of light stimulusGO:0050953540.011
cellular response to dna damage stimulusGO:00069742070.011
regulation of map kinase activityGO:00434051200.011
defecationGO:003042110.011
regulation of vesicle mediated transportGO:00606271390.011
response to inorganic substanceGO:0010035960.011
regulation of rho gtpase activityGO:0032319580.011
lateral line system developmentGO:004892510.011
actomyosin structure organizationGO:0031032560.011
establishment of protein localization to organelleGO:00725941180.011
Fly
wnt signaling pathwayGO:00160551880.011
positive regulation of protein kinase activityGO:00458601440.010
regulation of neuron deathGO:19012141340.010
renal system developmentGO:00720012250.010
endocytosisGO:00068971680.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
regulation of cytokine productionGO:00018172660.010
methylationGO:00322591340.010
sequestering of metal ionGO:0051238190.010
axon guidanceGO:00074111410.010
protein maturationGO:00516041760.010
metencephalon developmentGO:0022037890.010
neuron projection extensionGO:1990138640.010
response to monosaccharideGO:0034284670.010
circadian rhythmGO:00076231140.010
Fly
digestive tract developmentGO:00485651900.010
forebrain developmentGO:00309003020.010
limb developmentGO:00601731660.010
sympathetic neuron projection guidanceGO:009749140.010
myeloid cell differentiationGO:00300992330.010
neurotransmitter transportGO:0006836760.010
positive regulation of cell cycle processGO:0090068610.010
neuron neuron synaptic transmissionGO:0007270690.010
response to extracellular stimulusGO:00099911270.010
sperm motilityGO:0030317470.010
regulation of peptide transportGO:0090087910.010
regulation of receptor activityGO:0010469410.010
circadian regulation of gene expressionGO:0032922480.010

Rps6ka2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.055
disease of anatomical entityDOID:700.055
central nervous system diseaseDOID:33100.037
musculoskeletal system diseaseDOID:1700.018
disease of metabolismDOID:001466700.017
muscular diseaseDOID:008000000.017
muscle tissue diseaseDOID:6600.017
neuromuscular diseaseDOID:44000.015
neuropathyDOID:87000.015
neurodegenerative diseaseDOID:128900.014
myopathyDOID:42300.012