| protein modification by small protein conjugation | GO:0032446 | 187 | 0.182 | |
| histone modification | GO:0016570 | 159 | 0.165 | |
| chromatin modification | GO:0016568 | 187 | 0.151 | |
| chromatin organization | GO:0006325 | 206 | 0.124 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.105 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.095 | |
| protein ubiquitination | GO:0016567 | 171 | 0.078 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.066 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.062 | |
| cellular homeostasis | GO:0019725 | 240 | 0.059 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.056 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.049 | |
| forebrain development | GO:0030900 | 302 | 0.043 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.042 | |
| stem cell differentiation | GO:0048863 | 268 | 0.039 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.037 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.036 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.036 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.035 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.035 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.034 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.034 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.033 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.033 | |
| cell division | GO:0051301 | 120 | 0.033 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.033 | |
| stem cell maintenance | GO:0019827 | 130 | 0.033 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.031 | |
| stem cell development | GO:0048864 | 219 | 0.031 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.031 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.031 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.030 | |
| cognition | GO:0050890 | 149 | 0.030 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.030 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.030 | |
| heart morphogenesis | GO:0003007 | 178 | 0.030 | |
| dna metabolic process | GO:0006259 | 303 | 0.030 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.029 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.028 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.028 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.028 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.027 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.027 | |
| muscle system process | GO:0003012 | 141 | 0.027 | |
| axonogenesis | GO:0007409 | 274 | 0.027 | |
| cation transport | GO:0006812 | 399 | 0.027 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.026 | |
| blood circulation | GO:0008015 | 195 | 0.026 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.026 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.025 | |
| macromolecule methylation | GO:0043414 | 120 | 0.025 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.025 | |
| amine metabolic process | GO:0009308 | 45 | 0.025 | |
| methylation | GO:0032259 | 134 | 0.025 | |
| dna modification | GO:0006304 | 50 | 0.025 | |
| mapk cascade | GO:0000165 | 281 | 0.025 | |
| camera type eye development | GO:0043010 | 266 | 0.025 | |
| sensory perception | GO:0007600 | 245 | 0.025 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.025 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.025 | |
| circulatory system process | GO:0003013 | 197 | 0.024 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.024 | |
| axon guidance | GO:0007411 | 141 | 0.024 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.024 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.023 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.023 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.023 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.023 | |
| protein catabolic process | GO:0030163 | 221 | 0.023 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.023 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.023 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.023 | |
| multicellular organism growth | GO:0035264 | 161 | 0.023 | |
| membrane organization | GO:0061024 | 245 | 0.022 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.022 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.022 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.022 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.022 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.022 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.021 | |
| telomere maintenance | GO:0000723 | 19 | 0.021 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.021 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.021 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.021 | |
| mitochondrion organization | GO:0007005 | 134 | 0.021 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.020 | |
| cellular response to lipid | GO:0071396 | 145 | 0.020 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.020 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.020 | |
| response to light stimulus | GO:0009416 | 135 | 0.020 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.020 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.020 | |
| learning or memory | GO:0007611 | 148 | 0.020 | |
| ossification | GO:0001503 | 216 | 0.020 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.020 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.019 | |
| response to insulin | GO:0032868 | 100 | 0.019 | |
| response to growth factor | GO:0070848 | 198 | 0.019 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.019 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.019 | |
| protein localization to organelle | GO:0033365 | 185 | 0.019 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.019 | |
| regulation of nuclear division | GO:0051783 | 56 | 0.019 | |
| cation homeostasis | GO:0055080 | 212 | 0.019 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.019 | |
| nuclear transport | GO:0051169 | 139 | 0.019 | |
| nuclear division | GO:0000280 | 158 | 0.019 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.019 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.019 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.018 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.018 | |
| respiratory system development | GO:0060541 | 190 | 0.018 | |
| response to radiation | GO:0009314 | 165 | 0.018 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.018 | |
| intracellular protein transport | GO:0006886 | 204 | 0.018 | |
| telencephalon development | GO:0021537 | 186 | 0.018 | |
| ear development | GO:0043583 | 200 | 0.018 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.018 | |
| blastocyst development | GO:0001824 | 80 | 0.018 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.018 | |
| cytokine production | GO:0001816 | 319 | 0.018 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.017 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.017 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.017 | |
| chemotaxis | GO:0006935 | 247 | 0.017 | |
| regulation of cell activation | GO:0050865 | 289 | 0.017 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.017 | |
| cell aging | GO:0007569 | 35 | 0.017 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.017 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.017 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.016 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.016 | |
| muscle contraction | GO:0006936 | 101 | 0.016 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.016 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.016 | |
| skeletal system development | GO:0001501 | 356 | 0.016 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.016 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.016 | |
| telomere maintenance in response to dna damage | GO:0043247 | 4 | 0.016 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.016 | |
| protein acylation | GO:0043543 | 64 | 0.016 | |
| glucose homeostasis | GO:0042593 | 128 | 0.016 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.016 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.016 | |
| artery development | GO:0060840 | 53 | 0.016 | |
| cellular magnesium ion homeostasis | GO:0010961 | 3 | 0.015 | |
| transmembrane transport | GO:0055085 | 412 | 0.015 | |
| stem cell proliferation | GO:0072089 | 117 | 0.015 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.015 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.015 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.015 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.015 | |
| dna recombination | GO:0006310 | 92 | 0.015 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.015 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.015 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.014 | |
| oxidation reduction process | GO:0055114 | 342 | 0.014 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.014 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.014 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.014 | |
| cellular response to peptide | GO:1901653 | 92 | 0.014 | |
| maintenance of location | GO:0051235 | 89 | 0.014 | |
| regulation of system process | GO:0044057 | 200 | 0.014 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.014 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.014 | |
| neuron projection guidance | GO:0097485 | 141 | 0.014 | |
| organelle localization | GO:0051640 | 179 | 0.014 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.014 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.014 | |
| protein maturation | GO:0051604 | 176 | 0.014 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.014 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.014 | |
| organelle fission | GO:0048285 | 170 | 0.014 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.014 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.013 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.013 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.013 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.013 | |
| sodium ion transport | GO:0006814 | 73 | 0.013 | |
| histone methylation | GO:0016571 | 71 | 0.013 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.013 | |
| protection from non homologous end joining at telomere | GO:0031848 | 4 | 0.013 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.013 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.013 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.013 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.013 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.013 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.013 | |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.013 | |
| gland development | GO:0048732 | 330 | 0.012 | |
| regulation of protein localization | GO:0032880 | 231 | 0.012 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.012 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.012 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.012 | |
| regulation of cell division | GO:0051302 | 76 | 0.012 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.012 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.012 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.012 | |
| limb morphogenesis | GO:0035108 | 149 | 0.012 | |
| response to peptide hormone | GO:0043434 | 127 | 0.012 | |
| microtubule based process | GO:0007017 | 236 | 0.012 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.012 | |
| muscle tissue development | GO:0060537 | 308 | 0.012 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.012 | |
| protein targeting | GO:0006605 | 143 | 0.012 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.012 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.012 | |
| translesion synthesis | GO:0019985 | 1 | 0.012 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.012 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.012 | |
| atp metabolic process | GO:0046034 | 75 | 0.011 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.011 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.011 | |
| tube formation | GO:0035148 | 140 | 0.011 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.011 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.011 | |
| t cell activation | GO:0042110 | 289 | 0.011 | |
| immune effector process | GO:0002252 | 321 | 0.011 | |
| appendage development | GO:0048736 | 166 | 0.011 | |
| defecation | GO:0030421 | 1 | 0.011 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.011 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.011 | |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.011 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.011 | |
| memory | GO:0007613 | 58 | 0.011 | |
| rna processing | GO:0006396 | 105 | 0.011 | |
| epithelial cell development | GO:0002064 | 159 | 0.011 | |
| endomembrane system organization | GO:0010256 | 147 | 0.011 | |
| negative regulation of immune effector process | GO:0002698 | 55 | 0.011 | |
| positive regulation of growth | GO:0045927 | 104 | 0.011 | |
| sensory perception of mechanical stimulus | GO:0050954 | 107 | 0.011 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.011 | |
| eye photoreceptor cell differentiation | GO:0001754 | 41 | 0.010 | |
| negative regulation of mesenchymal cell proliferation | GO:0072201 | 3 | 0.010 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.010 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.010 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.010 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.010 | |
| regulation of ossification | GO:0030278 | 112 | 0.010 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.010 | |
| jnk cascade | GO:0007254 | 72 | 0.010 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.010 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.010 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.010 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.010 | |
| male gamete generation | GO:0048232 | 285 | 0.010 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.010 | |