Mus musculus

42 known processes

Comt

catechol-O-methyltransferase

(Aliases: D16Wsu103e,D330014B15Rik,Comt1)

Comt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.278
cellular lipid metabolic processGO:00442553230.137
cellular ketone metabolic processGO:0042180840.093
cellular amino acid metabolic processGO:00065201030.081
cellular amine metabolic processGO:0044106440.078
regulation of cellular ketone metabolic processGO:0010565660.078
response to organic cyclic compoundGO:00140701980.076
regulation of cellular amino acid metabolic processGO:000652150.071
amine metabolic processGO:0009308450.066
monocarboxylic acid metabolic processGO:00327871910.062
lipid biosynthetic processGO:00086101790.056
regulation of cellular amine metabolic processGO:0033238200.055
sulfur compound metabolic processGO:00067901000.054
negative regulation of protein metabolic processGO:00512482820.047
organic anion transportGO:00157111370.045
negative regulation of molecular functionGO:00440922580.045
glycerolipid metabolic processGO:00464861220.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
lipid modificationGO:0030258650.043
apoptotic signaling pathwayGO:00971903060.042
alcohol metabolic processGO:00060661160.042
maintenance of locationGO:0051235890.040
positive regulation of cellular amine metabolic processGO:003324050.040
cation transportGO:00068123990.039
organonitrogen compound biosynthetic processGO:19015661920.039
regulation of defense responseGO:00313472330.039
ion transmembrane transportGO:00342203610.038
cellular lipid catabolic processGO:0044242520.037
transmembrane transportGO:00550854120.037
small molecule catabolic processGO:0044282710.037
small molecule biosynthetic processGO:00442831320.036
negative regulation of cellular protein metabolic processGO:00322692470.035
fatty acid metabolic processGO:00066311210.035
carbohydrate derivative biosynthetic processGO:19011371830.034
organic hydroxy compound metabolic processGO:19016152030.034
regulation of mapk cascadeGO:00434082480.032
nucleoside phosphate metabolic processGO:00067533380.032
cofactor metabolic processGO:0051186800.032
response to organonitrogen compoundGO:00102432460.032
regulation of cytokine productionGO:00018172660.032
regulation of apoptotic signaling pathwayGO:20012331970.031
organophosphate biosynthetic processGO:00904071220.031
cell type specific apoptotic processGO:00972852680.031
regulation of cell activationGO:00508652890.030
innate immune responseGO:00450871570.030
lipid catabolic processGO:0016042690.030
cellular homeostasisGO:00197252400.030
lipid localizationGO:00108761260.030
peptidyl amino acid modificationGO:00181933360.029
negative regulation of cell proliferationGO:00082852960.029
protein maturationGO:00516041760.029
nucleobase containing small molecule metabolic processGO:00550863520.029
anion transportGO:00068201770.029
nucleotide metabolic processGO:00091173320.029
nitrogen compound transportGO:00717052710.029
purine containing compound metabolic processGO:00725213110.029
homeostasis of number of cellsGO:00488722100.029
inflammatory responseGO:00069542440.029
sterol metabolic processGO:0016125580.028
acylglycerol metabolic processGO:0006639550.028
cytoplasmic transportGO:00164822340.028
myeloid cell differentiationGO:00300992330.027
endocytosisGO:00068971680.027
ribose phosphate metabolic processGO:00196932910.026
cytokine productionGO:00018163190.026
leukocyte differentiationGO:00025213420.026
regulation of protein localizationGO:00328802310.026
response to acid chemicalGO:00011011110.026
multicellular organismal homeostasisGO:00488711640.025
mapk cascadeGO:00001652810.025
protein processingGO:00164851630.025
cholesterol metabolic processGO:0008203560.025
gland developmentGO:00487323300.025
organic acid catabolic processGO:0016054510.025
regulation of intracellular transportGO:00323861590.025
regulation of protein kinase activityGO:00458592320.025
cellular modified amino acid metabolic processGO:0006575630.024
ribonucleoside metabolic processGO:00091192450.024
regulation of organelle organizationGO:00330432890.023
organic cyclic compound catabolic processGO:19013612950.023
cellular chemical homeostasisGO:00550822150.023
membrane organizationGO:00610242450.023
regulation of homeostatic processGO:00328441820.023
cation transmembrane transportGO:00986552660.023
male gamete generationGO:00482322850.023
glycerolipid biosynthetic processGO:0045017500.023
skin developmentGO:00435882200.023
Mouse
reactive oxygen species metabolic processGO:0072593840.023
carboxylic acid biosynthetic processGO:0046394860.023
metal ion homeostasisGO:00550651890.023
macromolecule catabolic processGO:00090572810.022
immune effector processGO:00022523210.022
regulation of hormone levelsGO:00108172110.022
regulation of body fluid levelsGO:00508781620.022
amide transportGO:00428861380.022
carboxylic acid catabolic processGO:0046395510.022
peptide metabolic processGO:0006518460.022
purine nucleotide metabolic processGO:00061633020.022
positive regulation of protein phosphorylationGO:00019342420.022
response to inorganic substanceGO:0010035960.021
positive regulation of mapk cascadeGO:00434101700.021
regulation of hydrolase activityGO:00513362460.021
divalent inorganic cation homeostasisGO:00725071380.021
negative regulation of phosphorylationGO:00423261660.021
positive regulation of protein modification processGO:00314012990.021
purine ribonucleotide metabolic processGO:00091502900.021
glycerophospholipid metabolic processGO:0006650710.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.021
regulation of lymphocyte activationGO:00512492400.020
spermatogenesisGO:00072832840.020
regulation of neuron deathGO:19012141340.020
response to molecule of bacterial originGO:00022371430.020
heart contractionGO:0060047930.020
cellular response to organonitrogen compoundGO:00714171450.020
inorganic ion transmembrane transportGO:00986602340.020
t cell activationGO:00421102890.020
positive regulation of cell deathGO:00109422240.020
transmission of nerve impulseGO:0019226760.019
regulation of cellular response to stressGO:00801351590.019
organic acid transportGO:00158491010.019
intracellular protein transportGO:00068862040.019
regulation of kinase activityGO:00435492490.019
neuronal action potentialGO:0019228540.019
regulation of ion transportGO:00432692150.019
regulation of map kinase activityGO:00434051200.019
circulatory system processGO:00030131970.019
defense response to other organismGO:00985421970.019
muscle cell differentiationGO:00426922610.019
negative regulation of phosphorus metabolic processGO:00105631840.019
regulation of plasma lipoprotein particle levelsGO:0097006230.019
sensory perceptionGO:00076002450.019
Mouse
leukocyte migrationGO:00509001240.019
negative regulation of immune system processGO:00026832090.019
carbohydrate metabolic processGO:00059752300.018
endomembrane system organizationGO:00102561470.018
striated muscle tissue developmentGO:00147062930.018
forebrain developmentGO:00309003020.018
regulation of transferase activityGO:00513382630.018
regulation of membrane potentialGO:00423911920.018
cellular response to lipidGO:00713961450.018
inter male aggressive behaviorGO:000212130.018
protein localization to organelleGO:00333651850.018
regulation of leukocyte differentiationGO:19021051590.018
lymphocyte differentiationGO:00300982420.018
regulation of lipid metabolic processGO:00192161180.018
blood circulationGO:00080151950.017
epithelial cell developmentGO:00020641590.017
Mouse
tissue homeostasisGO:00018941150.017
response to oxidative stressGO:00069791230.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
neuron deathGO:00709971540.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
cation homeostasisGO:00550802120.017
phospholipid metabolic processGO:0006644870.017
ribonucleotide metabolic processGO:00092592910.017
inorganic cation transmembrane transportGO:00986622070.017
negative regulation of transferase activityGO:0051348850.017
posttranscriptional regulation of gene expressionGO:00106081550.017
dna metabolic processGO:00062593030.017
muscle tissue developmentGO:00605373080.017
sequestering of calcium ionGO:0051208180.017
negative regulation of cellular amine metabolic processGO:003323910.017
response to lipopolysaccharideGO:00324961280.017
cellular response to hormone stimulusGO:00328701500.017
positive regulation of response to woundingGO:1903036660.017
organonitrogen compound catabolic processGO:19015652640.016
action potentialGO:0001508780.016
regulation of t cell activationGO:00508631700.016
regulation of secretion by cellGO:19035302490.016
leukocyte proliferationGO:00706611720.016
g protein coupled receptor signaling pathwayGO:00071862430.016
ras protein signal transductionGO:0007265770.016
peptide transportGO:00158331330.016
carboxylic acid transportGO:00469421000.016
t cell differentiationGO:00302171740.016
lung developmentGO:00303241640.016
cellular nitrogen compound catabolic processGO:00442702800.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
renal system developmentGO:00720012250.016
peptidyl tyrosine modificationGO:00182121450.016
actin cytoskeleton organizationGO:00300362200.016
positive regulation of cytokine productionGO:00018191740.016
fatty acid oxidationGO:0019395280.016
negative regulation of apoptotic signaling pathwayGO:20012341040.016
divalent inorganic cation transportGO:00725111780.016
regulation of secretionGO:00510462740.016
lipid transportGO:0006869980.015
triglyceride metabolic processGO:0006641510.015
rho protein signal transductionGO:0007266320.015
anatomical structure homeostasisGO:00602491450.015
glycoprotein metabolic processGO:00091001160.015
calcium ion homeostasisGO:00550741270.015
chromatin organizationGO:00063252060.015
regulation of cellular catabolic processGO:00313292420.015
regulation of establishment of protein localizationGO:00702011810.015
epidermis developmentGO:00085441870.015
Mouse
chemotaxisGO:00069352470.015
regulation of anatomical structure sizeGO:00900661780.015
glycoprotein biosynthetic processGO:0009101890.015
purine nucleoside metabolic processGO:00422782410.015
respiratory system developmentGO:00605411900.015
regulation of system processGO:00440572000.015
nuclear transportGO:00511691390.015
regulation of ossificationGO:00302781120.015
skeletal system developmentGO:00015013560.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of cell migrationGO:00303342190.015
aromatic compound catabolic processGO:00194392860.015
heterocycle catabolic processGO:00467002800.014
purine ribonucleoside metabolic processGO:00461282410.014
positive regulation of apoptotic processGO:00430652170.014
response to monosaccharideGO:0034284670.014
cellular response to molecule of bacterial originGO:0071219830.014
negative regulation of phosphate metabolic processGO:00459361840.014
defense response to bacteriumGO:00427421190.014
regulation of response to woundingGO:19030341890.014
cellular metal ion homeostasisGO:00068751510.014
regulation of vesicle mediated transportGO:00606271390.014
response to light stimulusGO:00094161350.014
camera type eye developmentGO:00430102660.014
telencephalon developmentGO:00215371860.014
reactive nitrogen species metabolic processGO:200105700.014
nucleocytoplasmic transportGO:00069131390.014
sequestering of metal ionGO:0051238190.014
regulation of proteolysisGO:00301621640.014
kidney developmentGO:00018222130.014
nucleoside metabolic processGO:00091162460.014
organophosphate catabolic processGO:00464342320.014
multicellular organismal signalingGO:0035637910.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
hematopoietic progenitor cell differentiationGO:00022441430.014
blood vessel morphogenesisGO:00485142850.014
nucleotide catabolic processGO:00091662170.014
peptide secretionGO:00027901140.014
cellular ion homeostasisGO:00068731650.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
lateral inhibitionGO:004633110.014
digestive system developmentGO:00551232000.014
nucleoside triphosphate metabolic processGO:00091412300.014
regulation of protein serine threonine kinase activityGO:00719001570.014
regulation of peptidase activityGO:0052547960.013
response to radiationGO:00093141650.013
plasma membrane organizationGO:0007009900.013
skeletal system morphogenesisGO:00487052030.013
small gtpase mediated signal transductionGO:0007264970.013
modification dependent protein catabolic processGO:00199411330.013
heart processGO:0003015940.013
cellular response to growth factor stimulusGO:00713631970.013
mitochondrion organizationGO:00070051340.013
regulation of multi organism processGO:00439001110.013
rhythmic processGO:00485111740.013
positive regulation of lymphocyte activationGO:00512511400.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
response to oxygen levelsGO:0070482620.013
nucleotide biosynthetic processGO:0009165780.013
urogenital system developmentGO:00016552610.013
response to extracellular stimulusGO:00099911270.013
ossificationGO:00015032160.013
positive regulation of reactive oxygen species metabolic processGO:2000379110.013
cellular response to acid chemicalGO:0071229680.013
cellular response to biotic stimulusGO:0071216920.013
positive regulation of secretionGO:00510471300.013
lipid oxidationGO:0034440290.013
response to insulinGO:00328681000.013
wound healingGO:00420601570.013
axonogenesisGO:00074092740.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
muscle system processGO:00030121410.013
negative regulation of cellular component organizationGO:00511291940.013
ribonucleotide catabolic processGO:00092612080.013
neuron apoptotic processGO:00514021420.013
monocarboxylic acid catabolic processGO:0072329270.013
myeloid leukocyte differentiationGO:00025731190.013
fat cell differentiationGO:00454441600.013
morphogenesis of a branching structureGO:00017632030.012
heart morphogenesisGO:00030071780.012
carbohydrate derivative catabolic processGO:19011362310.012
synaptic transmissionGO:00072683290.012
protein ubiquitinationGO:00165671710.012
wnt signaling pathwayGO:00160551880.012
cell adhesionGO:00071553290.012
glucose homeostasisGO:00425931280.012
cellular calcium ion homeostasisGO:00068741190.012
organic hydroxy compound transportGO:0015850930.012
extracellular structure organizationGO:00430621480.012
neutral lipid metabolic processGO:0006638570.012
multicellular organism growthGO:00352641610.012
cellular response to peptideGO:1901653920.012
lymphocyte proliferationGO:00466511640.012
regulation of ion transmembrane transportGO:00347651190.012
divalent metal ion transportGO:00708381720.012
hair cycleGO:0042633900.012
regulation of cell motilityGO:20001452360.012
response to growth factorGO:00708481980.012
positive regulation of protein kinase activityGO:00458601440.012
regulation of cell cycleGO:00517262810.012
protein secretionGO:00093061110.012
nuclear importGO:0051170950.012
muscle contractionGO:00069361010.012
sensory organ morphogenesisGO:00905962420.012
cellular protein complex assemblyGO:00436231160.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
ketone catabolic processGO:004218230.012
glutathione metabolic processGO:0006749160.012
positive regulation of cell motilityGO:20001471160.012
establishment of protein localization to organelleGO:00725941180.012
ensheathment of neuronsGO:0007272760.012
peptidyl tyrosine phosphorylationGO:00181081430.012
morphogenesis of a branching epitheliumGO:00611381930.012
interleukin 8 productionGO:003263740.012
response to vitamin aGO:003318910.012
respiratory tube developmentGO:00303231670.012
response to peptideGO:19016521360.011
protein oligomerizationGO:0051259670.011
response to steroid hormoneGO:0048545560.011
positive regulation of cell activationGO:00508671580.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
negative regulation of protein modification processGO:00314001630.011
protein modification by small protein conjugation or removalGO:00706472070.011
protein catabolic processGO:00301632210.011
connective tissue developmentGO:00614481790.011
ribonucleoside catabolic processGO:00424542060.011
nucleoside catabolic processGO:00091642060.011
negative regulation of intracellular signal transductionGO:19025321670.011
regulation of lymphocyte differentiationGO:00456191070.011
regulation of protein transportGO:00512231630.011
epithelial cell proliferationGO:00506731740.011
leukocyte mediated immunityGO:00024431740.011
cellular response to oxidative stressGO:0034599760.011
regulation of cell adhesionGO:00301551540.011
cofactor transportGO:005118140.011
regulation of protein catabolic processGO:00421761080.011
positive regulation of defense responseGO:00313491240.011
nucleoside phosphate catabolic processGO:19012922220.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
cellularizationGO:000734910.011
phospholipid biosynthetic processGO:0008654360.011
developmental growth involved in morphogenesisGO:00605601380.011
nadph regenerationGO:000674020.011
regulation of protein maturationGO:1903317960.011
myeloid cell homeostasisGO:00022621140.011
regulation of neuron projection developmentGO:00109751690.011
carbohydrate homeostasisGO:00335001280.011
epithelial tube morphogenesisGO:00605623030.011
protein localization to membraneGO:00726571080.011
phagocytosisGO:0006909660.011
locomotory behaviorGO:00076261950.011
regulation of interleukin 8 productionGO:003267730.011
methylationGO:00322591340.011
regulation of neuron apoptotic processGO:00435231220.011
plasma lipoprotein particle clearanceGO:0034381130.011
regulation of transmembrane transportGO:00347621280.011
regulation of cytoplasmic transportGO:19036491120.011
positive regulation of secretion by cellGO:19035321140.011
cellular response to peptide hormone stimulusGO:0071375920.011
cellular response to cytokine stimulusGO:00713451890.011
purine ribonucleotide biosynthetic processGO:0009152590.011
response to nutrient levelsGO:00316671090.011
positive regulation of fatty acid oxidationGO:004632140.011
covalent chromatin modificationGO:00165691630.011
negative regulation of neuron apoptotic processGO:0043524920.011
positive regulation of proteolysisGO:0045862850.011
regulation of leukocyte proliferationGO:00706631210.011
response to peptide hormoneGO:00434341270.011
protein localization to nucleusGO:00345041210.011
cell activation involved in immune responseGO:00022631260.011
purine nucleotide catabolic processGO:00061952110.011
chromatin modificationGO:00165681870.011
glycosyl compound metabolic processGO:19016572460.011
positive regulation of programmed cell deathGO:00430682180.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
germ cell developmentGO:00072811850.011
protein importGO:00170381010.011
lymphocyte mediated immunityGO:00024491390.011
positive regulation of cell developmentGO:00107202370.010
embryonic organ morphogenesisGO:00485622760.010
nucleoside monophosphate metabolic processGO:0009123850.010
purine containing compound biosynthetic processGO:0072522700.010
cellular response to lipopolysaccharideGO:0071222770.010
compound eye developmentGO:004874910.010
placenta developmentGO:00018901400.010
positive regulation of kinase activityGO:00336741550.010
reactive oxygen species biosynthetic processGO:190340980.010
blood coagulationGO:0007596760.010
myelinationGO:0042552740.010
cell chemotaxisGO:0060326810.010
hair follicle developmentGO:0001942850.010
cellular alcohol metabolic processGO:004410730.010
regulation of inflammatory responseGO:00507271470.010
skeletal muscle organ developmentGO:00605381630.010
organelle fissionGO:00482851700.010
angiogenesisGO:00015252010.010
purine nucleoside catabolic processGO:00061522050.010
calcium ion transportGO:00068161590.010
spermatid differentiationGO:00485151150.010
nucleoside phosphate biosynthetic processGO:1901293790.010
erythrocyte differentiationGO:0030218880.010
response to metal ionGO:0010038470.010
purine ribonucleotide catabolic processGO:00091542080.010
hormone secretionGO:00468791280.010

Comt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
disease of metabolismDOID:001466700.019
sensory system diseaseDOID:005015500.015
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
central nervous system diseaseDOID:33100.011
immune system diseaseDOID:291400.011
bone diseaseDOID:008000100.011
eye and adnexa diseaseDOID:149200.010
hematopoietic system diseaseDOID:7400.010