Mus musculus

154 known processes

Prkaa1

protein kinase, AMP-activated, alpha 1 catalytic subunit

(Aliases: AI450832,AMPKalpha1,AI194361,C130083N04Rik,AL024255)

Prkaa1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysis involved in cellular protein catabolic processGO:00516031470.213
protein modification by small protein conjugation or removalGO:00706472070.187
macromolecule catabolic processGO:00090572810.182
generation of precursor metabolites and energyGO:00060911030.170
Rat
lipid homeostasisGO:0055088630.118
Rat
heterocycle catabolic processGO:00467002800.102
maintenance of locationGO:0051235890.101
Fly
protein ubiquitinationGO:00165671710.101
aromatic compound catabolic processGO:00194392860.088
organic cyclic compound catabolic processGO:19013612950.085
purine nucleoside metabolic processGO:00422782410.080
cell agingGO:0007569350.077
Yeast
energy derivation by oxidation of organic compoundsGO:0015980770.076
nucleoside phosphate metabolic processGO:00067533380.073
regulation of glucose metabolic processGO:0010906600.071
Yeast
modification dependent macromolecule catabolic processGO:00436321330.069
negative regulation of cellular protein metabolic processGO:00322692470.064
Yeast
nucleotide metabolic processGO:00091173320.063
protein modification by small protein conjugationGO:00324461870.062
cellular macromolecule catabolic processGO:00442652060.062
hexose metabolic processGO:0019318980.061
regulation of cell cycleGO:00517262810.059
Worm
meiotic cell cycleGO:00513211220.058
Worm
regulation of cellular carbohydrate metabolic processGO:0010675750.056
Yeast Rat
modification dependent protein catabolic processGO:00199411330.056
ribonucleotide metabolic processGO:00092592910.052
intracellular protein transportGO:00068862040.051
lipid localizationGO:00108761260.049
Fly
cellular nitrogen compound catabolic processGO:00442702800.047
cation transmembrane transportGO:00986552660.046
ion transmembrane transportGO:00342203610.046
monosaccharide metabolic processGO:00059961060.045
transmembrane transportGO:00550854120.045
nucleobase containing small molecule metabolic processGO:00550863520.044
membrane organizationGO:00610242450.044
purine nucleotide metabolic processGO:00061633020.043
cholesterol homeostasisGO:0042632440.042
regulation of cellular ketone metabolic processGO:0010565660.042
Yeast
cellular ketone metabolic processGO:0042180840.041
Yeast
nucleoside triphosphate metabolic processGO:00091412300.040
carbohydrate transportGO:0008643620.039
Rat
positive regulation of cell cycleGO:0045787920.037
Worm
purine containing compound metabolic processGO:00725213110.036
nucleoside metabolic processGO:00091162460.036
protein catabolic processGO:00301632210.036
glycoprotein biosynthetic processGO:0009101890.035
proteasomal protein catabolic processGO:0010498980.035
inorganic cation transmembrane transportGO:00986622070.034
cation transportGO:00068123990.032
cellular divalent inorganic cation homeostasisGO:00725031270.032
cellular lipid metabolic processGO:00442553230.031
ubiquitin dependent protein catabolic processGO:00065111290.031
sterol homeostasisGO:0055092450.031
regulation of engulfment of apoptotic cellGO:190107420.031
nucleocytoplasmic transportGO:00069131390.030
compound eye developmentGO:004874910.030
organic anion transportGO:00157111370.030
negative regulation of phosphorus metabolic processGO:00105631840.029
protein modification by small protein removalGO:0070646210.029
glycosyl compound metabolic processGO:19016572460.029
purine nucleoside catabolic processGO:00061522050.029
purine ribonucleoside catabolic processGO:00461302050.029
inorganic ion transmembrane transportGO:00986602340.028
protein localization to organelleGO:00333651850.028
purine ribonucleoside triphosphate catabolic processGO:00092071990.028
regulation of carbohydrate metabolic processGO:0006109750.028
Yeast Rat
carbohydrate derivative biosynthetic processGO:19011371830.027
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.027
hexose transportGO:0008645560.027
Rat
polysaccharide biosynthetic processGO:0000271200.026
dna templated transcriptional preinitiation complex assemblyGO:007089740.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
dephosphorylationGO:00163111290.024
purine containing compound catabolic processGO:00725232130.024
ribose phosphate metabolic processGO:00196932910.024
anion transportGO:00068201770.024
response to starvationGO:0042594650.024
carbohydrate derivative catabolic processGO:19011362310.024
purine ribonucleoside metabolic processGO:00461282410.023
multi multicellular organism processGO:00447061090.023
cellular response to external stimulusGO:0071496880.023
regulation of establishment of protein localizationGO:00702011810.023
protein oligomerizationGO:0051259670.023
Rat
positive regulation of cell deathGO:00109422240.022
Mouse
carbohydrate metabolic processGO:00059752300.022
ribonucleoside monophosphate metabolic processGO:0009161800.022
regulation of proteolysisGO:00301621640.022
cellular protein catabolic processGO:00442571550.022
endocytosisGO:00068971680.021
Fly
regulation of purine nucleotide metabolic processGO:19005421690.021
cellular carbohydrate metabolic processGO:00442621190.021
Yeast Rat
stem cell developmentGO:00488642190.021
organophosphate catabolic processGO:00464342320.021
protein localization to plasma membraneGO:0072659570.021
purine ribonucleotide metabolic processGO:00091502900.021
glucose transportGO:0015758560.020
Rat
negative regulation of protein metabolic processGO:00512482820.020
Yeast
response to extracellular stimulusGO:00099911270.020
nuclear divisionGO:00002801580.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
divalent inorganic cation transportGO:00725111780.020
negative regulation of cellular response to growth factor stimulusGO:0090288460.020
meiotic nuclear divisionGO:00071261150.020
purine ribonucleotide catabolic processGO:00091542080.020
cellularizationGO:000734910.020
hematopoietic progenitor cell differentiationGO:00022441430.019
ribonucleoside metabolic processGO:00091192450.019
calcium ion homeostasisGO:00550741270.018
cellular amino acid metabolic processGO:00065201030.018
cell adhesionGO:00071553290.018
Yeast
positive regulation of hydrolase activityGO:00513451480.018
microtubule based processGO:00070172360.018
ribonucleotide catabolic processGO:00092612080.018
nitrogen compound transportGO:00717052710.018
positive regulation of programmed cell deathGO:00430682180.018
Mouse
positive regulation of cellular catabolic processGO:00313311480.018
regulation of ion transportGO:00432692150.018
regulation of cytoplasmic transportGO:19036491120.018
regulation of gluconeogenesisGO:0006111300.018
Yeast
glycoprotein metabolic processGO:00091001160.017
retrograde transport endosome to golgiGO:004214720.017
energy reserve metabolic processGO:0006112390.017
sequestering of triglycerideGO:003073060.017
Fly
response to nutrient levelsGO:00316671090.017
cofactor transportGO:005118140.017
lymphocyte differentiationGO:00300982420.017
negative regulation of cell proliferationGO:00082852960.017
Worm
ribonucleoside triphosphate metabolic processGO:00091992200.017
nucleoside catabolic processGO:00091642060.017
cytoplasmic transportGO:00164822340.017
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.017
cellular metal ion homeostasisGO:00068751510.017
glucan biosynthetic processGO:0009250140.017
cellular response to growth factor stimulusGO:00713631970.017
mesodermal cell migrationGO:000807840.017
positive regulation of tor signalingGO:003200830.016
cellular response to nutrient levelsGO:0031669640.016
cellular response to starvationGO:0009267570.016
positive regulation of nfat protein import into nucleusGO:005153310.016
organonitrogen compound catabolic processGO:19015652640.016
nucleoside triphosphate catabolic processGO:00091432050.016
regulation of protein transportGO:00512231630.016
protein deubiquitinationGO:0016579190.016
negative regulation of cellular amine metabolic processGO:003323910.016
positive regulation of glucose metabolic processGO:0010907210.016
Yeast
positive regulation of leukocyte differentiationGO:1902107860.016
positive regulation of dna templated transcription elongationGO:003278620.016
developmental maturationGO:00217001930.016
purine nucleoside triphosphate catabolic processGO:00091462030.015
multicellular organism growthGO:00352641610.015
glycogen metabolic processGO:0005977320.015
regulation of protein catabolic processGO:00421761080.015
muscle cell differentiationGO:00426922610.015
nucleobase containing compound transportGO:0015931270.015
leukocyte differentiationGO:00025213420.015
endomembrane system organizationGO:00102561470.015
cellular ion homeostasisGO:00068731650.015
regulation of intracellular protein transportGO:0033157820.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.015
nucleoside phosphate catabolic processGO:19012922220.015
divalent inorganic cation homeostasisGO:00725071380.015
oxidation reduction processGO:00551143420.015
purine nucleoside triphosphate metabolic processGO:00091442260.014
purine nucleotide catabolic processGO:00061952110.014
response to oxidative stressGO:00069791230.014
atp metabolic processGO:0046034750.014
establishment of vesicle localizationGO:0051650810.014
regulation of purine nucleotide catabolic processGO:00331211220.014
nucleotide catabolic processGO:00091662170.014
organic hydroxy compound metabolic processGO:19016152030.014
cellular polysaccharide metabolic processGO:0044264380.014
positive regulation of engulfment of apoptotic cellGO:190107610.014
cell divisionGO:00513011200.014
macromolecule methylationGO:00434141200.014
behavioral response to starvationGO:004259520.014
Fly
neural precursor cell proliferationGO:00613511210.014
Mouse
purine nucleotide transportGO:001586520.013
cellular calcium ion homeostasisGO:00068741190.013
macromolecule glycosylationGO:0043413550.013
cell type specific apoptotic processGO:00972852680.013
positive regulation of cellular carbohydrate metabolic processGO:0010676290.013
Yeast Rat
positive regulation of sequestering of triglycerideGO:001089040.013
nucleic acid phosphodiester bond hydrolysisGO:0090305490.013
mitotic cell cycleGO:00002781950.013
Worm Fly
regulation of protein kinase activityGO:00458592320.013
metal ion homeostasisGO:00550651890.013
cellular homeostasisGO:00197252400.013
positive regulation of adaptive immune responseGO:0002821610.013
cellular response to transforming growth factor beta stimulusGO:0071560880.013
regulation of nucleoside metabolic processGO:00091181300.013
mrna metabolic processGO:0016071840.013
positive regulation of carbohydrate metabolic processGO:0045913300.013
Yeast Rat
axonogenesisGO:00074092740.013
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
lipid biosynthetic processGO:00086101790.013
bone developmentGO:00603481200.013
regulation of secretionGO:00510462740.013
negative regulation of protein modification processGO:00314001630.013
glycerolipid metabolic processGO:00464861220.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
regulation of cellular amino acid metabolic processGO:000652150.012
regulation of protein localizationGO:00328802310.012
negative regulation of phosphate metabolic processGO:00459361840.012
glucan metabolic processGO:0044042320.012
response to inorganic substanceGO:0010035960.012
glycosyl compound catabolic processGO:19016582060.012
nucleoside monophosphate metabolic processGO:0009123850.012
replicative cell agingGO:000130220.012
Yeast
cellular protein complex assemblyGO:00436231160.012
vesicle organizationGO:0016050600.012
organophosphate biosynthetic processGO:00904071220.012
cation homeostasisGO:00550802120.012
regulation of tor signalingGO:0032006170.012
divalent metal ion transportGO:00708381720.012
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.012
calcium ion transmembrane transportGO:0070588850.012
response to growth factorGO:00708481980.012
stem cell differentiationGO:00488632680.012
synaptic transmissionGO:00072683290.012
oocyte constructionGO:000730820.012
positive regulation of cellular amine metabolic processGO:003324050.012
wnt signaling pathwayGO:00160551880.012
positive regulation of phagocytosis engulfmentGO:006010030.012
radial glia guided migration of purkinje cellGO:002194260.012
neuron projection guidanceGO:00974851410.012
Fly
regulation of cell shapeGO:0008360390.011
monosaccharide biosynthetic processGO:0046364440.011
Yeast
ribonucleoside catabolic processGO:00424542060.011
skeletal system developmentGO:00015013560.011
multicellular organismal homeostasisGO:00488711640.011
Rat
regulation of cellular response to stressGO:00801351590.011
positive regulation of t helper 1 cell differentiationGO:004562740.011
positive regulation of protein transportGO:0051222930.011
nuclear transportGO:00511691390.011
proteoglycan biosynthetic processGO:0030166200.011
connective tissue developmentGO:00614481790.011
positive regulation of nucleotide catabolic processGO:0030813880.011
locomotory behaviorGO:00076261950.011
protein glycosylationGO:0006486550.011
regulation of lipid metabolic processGO:00192161180.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
regulation of cellular catabolic processGO:00313292420.011
protein autophosphorylationGO:0046777610.011
regulation of nucleotide catabolic processGO:00308111220.011
regulation of protein complex assemblyGO:0043254830.011
segmentationGO:0035282930.011
regulation of activation of jak2 kinase activityGO:001053410.011
cellular response to extracellular stimulusGO:0031668810.011
pole plasm assemblyGO:000731520.011
negative regulation of phosphorylationGO:00423261660.011
regulation of hydrolase activityGO:00513362460.011
monoubiquitinated histone h2a deubiquitinationGO:003552210.011
multi organism reproductive behaviorGO:0044705290.011
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.011
g protein coupled receptor signaling pathwayGO:00071862430.011
protein importGO:00170381010.011
sensory organ morphogenesisGO:00905962420.011
monosaccharide transportGO:0015749580.011
Rat
positive regulation of apoptotic processGO:00430652170.011
Mouse
cellular response to peptide hormone stimulusGO:0071375920.011
Rat
regulation of kinase activityGO:00435492490.010
positive regulation of nucleotide metabolic processGO:00459811140.010
adult behaviorGO:00305341350.010
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.010
sequestering of metal ionGO:0051238190.010
nuclear importGO:0051170950.010
organonitrogen compound biosynthetic processGO:19015661920.010
regulation of cellular protein catabolic processGO:1903362610.010
microtubule cytoskeleton organizationGO:00002261570.010
glycosylationGO:0070085620.010
response to transforming growth factor betaGO:0071559880.010
fertilizationGO:00095661270.010
muscle fiber developmentGO:0048747760.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.010
regulation of t cell activationGO:00508631700.010

Prkaa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.027
disease of cellular proliferationDOID:1456600.027
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
eye and adnexa diseaseDOID:149200.017
sensory system diseaseDOID:005015500.017
retinal diseaseDOID:567900.017
eye diseaseDOID:561400.017
organ system cancerDOID:005068600.015
retinal degenerationDOID:846600.014
central nervous system diseaseDOID:33100.012
intestinal cancerDOID:1015500.011
gastrointestinal system cancerDOID:311900.011
large intestine cancerDOID:567200.011
colorectal cancerDOID:925600.011
colon cancerDOID:21900.011