Mus musculus

137 known processes

Tsc1

tuberous sclerosis 1

(Aliases: hamartin,mKIAA0243)

Tsc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of insulin receptor signaling pathwayGO:0046626210.914
Fly
positive regulation of ras gtpase activityGO:0032320650.862
Human Fly
regulation of protein kinase activityGO:00458592320.858
negative regulation of insulin receptor signaling pathwayGO:0046627140.845
Fly
cellular response to dna damage stimulusGO:00069742070.813
negative regulation of organ growthGO:0046621170.779
Fly
protein transport into membrane raftGO:003259640.764
negative regulation of phosphate metabolic processGO:00459361840.709
pole plasm assemblyGO:000731520.709
cellular response to insulin stimulusGO:0032869780.698
Fly
negative regulation of transferase activityGO:0051348850.680
regulation of kinase activityGO:00435492490.676
negative regulation of cell sizeGO:004579230.673
negative regulation of phosphorus metabolic processGO:00105631840.664
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.655
negative regulation of cellular protein metabolic processGO:00322692470.638
Human
lateral inhibitionGO:004633110.635
negative regulation of phosphorylationGO:00423261660.633
regulation of synaptic growth at neuromuscular junctionGO:000858240.633
regulation of autophagyGO:0010506300.633
Fly
negative regulation of tor signalingGO:0032007130.632
Human Fly
ribonucleoside metabolic processGO:00091192450.631
Human Fly
positive regulation of gtpase activityGO:0043547850.590
Human Fly
gtp catabolic processGO:00061841430.588
Human Fly
purine ribonucleotide metabolic processGO:00091502900.571
Human Fly
negative regulation of protein modification processGO:00314001630.565
autophagyGO:0006914450.565
Fly
oocyte axis specificationGO:000730920.563
purine nucleoside metabolic processGO:00422782410.556
Human Fly
regulation of cell cycleGO:00517262810.552
Fly
nucleoside triphosphate metabolic processGO:00091412300.548
Human Fly
glycosyl compound catabolic processGO:19016582060.538
Human Fly
regulation of nucleotide metabolic processGO:00061401690.537
Human Fly
positive regulation of cellular catabolic processGO:00313311480.534
Human Fly
organic cyclic compound catabolic processGO:19013612950.533
Human Fly
regulation of gtp catabolic processGO:00331241130.523
Human Fly
ribonucleoside catabolic processGO:00424542060.508
Human Fly
negative regulation of growthGO:0045926990.507
Fly
ribonucleoside triphosphate catabolic processGO:00092031990.506
Human Fly
positive regulation of autophagyGO:001050890.505
Fly
positive regulation of nucleoside metabolic processGO:0045979910.501
Human Fly
negative regulation of protein serine threonine kinase activityGO:0071901490.494
positive regulation of nucleotide metabolic processGO:00459811140.479
Human Fly
cellular response to peptideGO:1901653920.478
Fly
cellular response to peptide hormone stimulusGO:0071375920.473
Fly
carbohydrate transportGO:0008643620.467
guanosine containing compound catabolic processGO:19010691440.466
Human Fly
negative regulation of map kinase activityGO:0043407340.463
regulation of cellular amine metabolic processGO:0033238200.463
regulation of mapk cascadeGO:00434082480.456
regulation of ras protein signal transductionGO:00465781140.453
Human Fly
cellular response to organonitrogen compoundGO:00714171450.453
Fly
nucleocytoplasmic transportGO:00069131390.441
Human
nucleoside phosphate metabolic processGO:00067533380.441
Human Fly
regulation of cell sizeGO:0008361720.436
response to insulinGO:00328681000.436
Human Fly
negative regulation of protein phosphorylationGO:00019331260.428
germ cell developmentGO:00072811850.427
Fly
purine containing compound metabolic processGO:00725213110.423
Human Fly
negative regulation of mapk cascadeGO:0043409650.420
guanosine containing compound metabolic processGO:19010681440.418
Human Fly
positive regulation of protein modification processGO:00314012990.418
aromatic compound catabolic processGO:00194392860.408
Human Fly
neural tube closureGO:0001843900.407
nucleoside triphosphate catabolic processGO:00091432050.397
Human Fly
response to nutrient levelsGO:00316671090.396
Fly
pallium developmentGO:00215431200.395
insulin receptor signaling pathwayGO:0008286490.393
Fly
negative regulation of kinase activityGO:0033673810.392
regulation of nucleoside metabolic processGO:00091181300.389
Human Fly
positive regulation of hydrolase activityGO:00513451480.387
Human Fly
synapse organizationGO:00508081250.386
cellular nitrogen compound catabolic processGO:00442702800.383
Human Fly
purine ribonucleotide catabolic processGO:00091542080.382
Human Fly
mapk cascadeGO:00001652810.379
purine ribonucleoside triphosphate catabolic processGO:00092071990.376
Human Fly
synaptic growth at neuromuscular junctionGO:005112460.371
response to light stimulusGO:00094161350.368
ribonucleotide metabolic processGO:00092592910.367
Human Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.365
Fly
negative regulation of synapse assemblyGO:005196430.364
limbic system developmentGO:0021761720.349
nucleobase containing small molecule metabolic processGO:00550863520.349
Human Fly
regulation of nucleotide catabolic processGO:00308111220.348
Human Fly
positive regulation of nucleotide catabolic processGO:0030813880.342
Human Fly
posttranscriptional regulation of gene expressionGO:00106081550.338
Human
regulation of purine nucleotide metabolic processGO:19005421690.332
Human Fly
purine nucleotide metabolic processGO:00061633020.330
Human Fly
negative regulation of cell cycleGO:00457861230.324
regulation of wnt signaling pathwayGO:00301111230.315
response to peptideGO:19016521360.310
Human Fly
glucose importGO:0046323320.309
embryonic epithelial tube formationGO:00018381300.309
purine nucleoside catabolic processGO:00061522050.307
Human Fly
regulation of cellular catabolic processGO:00313292420.305
Human Fly
epithelial tube morphogenesisGO:00605623030.302
negative regulation of glial cell proliferationGO:006025340.301
endomembrane system organizationGO:00102561470.300
regulation of tor signalingGO:0032006170.297
Human Zebrafish Fly
positive regulation of purine nucleotide catabolic processGO:0033123880.292
Human Fly
response to organonitrogen compoundGO:00102432460.290
Human Fly
developmental maturationGO:00217001930.284
response to extracellular stimulusGO:00099911270.280
Fly
chemotaxisGO:00069352470.277
regulation of transferase activityGO:00513382630.277
plasma membrane organizationGO:0007009900.275
epithelial tube formationGO:00721751300.274
glucose transportGO:0015758560.268
organonitrogen compound catabolic processGO:19015652640.263
Human Fly
dna metabolic processGO:00062593030.263
oocyte anterior posterior axis specificationGO:000731420.263
regulation of cell growthGO:0001558910.263
Fly
chromosome separationGO:0051304140.263
cellular ketone metabolic processGO:0042180840.258
negative regulation of epithelial cell proliferationGO:0050680640.258
purine ribonucleoside metabolic processGO:00461282410.257
Human Fly
oocyte constructionGO:000730820.257
ribonucleotide catabolic processGO:00092612080.255
Human Fly
spermatid developmentGO:00072861080.253
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.250
protein localization to nucleusGO:00345041210.249
wnt signaling pathwayGO:00160551880.248
epithelial cell proliferationGO:00506731740.247
regulation of cellular component sizeGO:00325351210.246
regulation of hippo signalingGO:003533010.243
odontogenesisGO:0042476780.242
negative regulation of molecular functionGO:00440922580.242
female gamete generationGO:0007292740.241
Fly
oocyte differentiationGO:0009994350.239
purine ribonucleoside catabolic processGO:00461302050.238
Human Fly
organ growthGO:00352651170.236
Fly
spermatid differentiationGO:00485151150.236
oogenesisGO:0048477560.234
Fly
cellular response to hormone stimulusGO:00328701500.234
Fly
protein kinase b signalingGO:0043491740.230
purine nucleotide catabolic processGO:00061952110.230
Human Fly
protein localization to organelleGO:00333651850.228
cell divisionGO:00513011200.224
tor signalingGO:0031929210.223
Human Zebrafish Fly
organelle fissionGO:00482851700.222
nucleoside catabolic processGO:00091642060.221
Human Fly
response to radiationGO:00093141650.221
endocytosisGO:00068971680.217
response to oxygen levelsGO:0070482620.216
Fly
cell growthGO:00160491300.211
Fly
establishment of protein localization to organelleGO:00725941180.211
negative regulation of cell growthGO:0030308440.210
Fly
male gamete generationGO:00482322850.210
negative regulation of protein metabolic processGO:00512482820.209
Human
glycosyl compound metabolic processGO:19016572460.199
Human Fly
acute inflammatory responseGO:0002526410.198
neural tube developmentGO:00219151600.197
membrane organizationGO:00610242450.191
regulation of mitotic cell cycleGO:00073461260.189
negative regulation of dna replicationGO:000815640.188
nucleotide metabolic processGO:00091173320.186
Human Fly
response to decreased oxygen levelsGO:0036293590.186
Fly
neural tube formationGO:00018411080.184
cell type specific apoptotic processGO:00972852680.181
regulation of epithelial cell proliferationGO:00506781410.179
cell fate commitmentGO:00451652100.177
regulation of actin cytoskeleton organizationGO:0032956840.176
Human
regulation of protein stabilityGO:0031647520.174
Human
heterocycle catabolic processGO:00467002800.172
Human Fly
gtp metabolic processGO:00460391440.171
Human Fly
protein localization to plasma membraneGO:0072659570.170
negative regulation of cell proliferationGO:00082852960.169
tube closureGO:0060606910.169
actin filament organizationGO:00070151130.166
Human
positive regulation of protein phosphorylationGO:00019342420.165
negative regulation of cellular amino acid metabolic processGO:004576300.163
nucleoside phosphate catabolic processGO:19012922220.160
Human Fly
protein import into nucleusGO:0006606950.158
regulation of endocytosisGO:0030100690.157
purine containing compound catabolic processGO:00725232130.156
Human Fly
negative regulation of cellular component organizationGO:00511291940.154
negative regulation of wnt signaling pathwayGO:0030178730.150
cellular amine metabolic processGO:0044106440.149
positive regulation of organelle organizationGO:00106381280.148
meiotic nuclear divisionGO:00071261150.148
protein modification by small protein conjugation or removalGO:00706472070.147
purine nucleoside triphosphate metabolic processGO:00091442260.144
Human Fly
protein localization to membrane raftGO:190304440.143
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252420.143
nucleotide catabolic processGO:00091662170.143
Human Fly
regulation of vesicle mediated transportGO:00606271390.142
sperm individualizationGO:000729110.141
negative regulation of cellular amine metabolic processGO:003323910.140
angiogenesisGO:00015252010.140
cellularizationGO:000734910.139
response to nutrientGO:0007584120.139
Fly
dna damage checkpointGO:0000077260.139
determination of adult lifespanGO:0008340110.137
Fly
regulation of cellular component biogenesisGO:00440871810.137
Human
intracellular protein transportGO:00068862040.137
cell maturationGO:00484691270.135
carbohydrate derivative catabolic processGO:19011362310.135
Human Fly
phagocytosisGO:0006909660.133
regulation of protein kinase b signalingGO:0051896560.132
ubiquitin dependent protein catabolic processGO:00065111290.131
nucleoside metabolic processGO:00091162460.131
Human Fly
protein importGO:00170381010.130
regulation of anatomical structure sizeGO:00900661780.128
amine metabolic processGO:0009308450.127
hippo signalingGO:0035329110.125
primary neural tube formationGO:0014020950.124
cell cell signaling involved in cell fate commitmentGO:0045168350.117
nuclear importGO:0051170950.117
positive regulation of apoptotic processGO:00430652170.116
negative regulation of leukocyte differentiationGO:1902106510.115
tyrosine phosphorylation of stat5 proteinGO:004250690.115
negative regulation of protein kinase b signalingGO:0051898180.115
modification dependent protein catabolic processGO:00199411330.115
protein localization to membraneGO:00726571080.113
protein oligomerizationGO:0051259670.112
modification dependent macromolecule catabolic processGO:00436321330.108
regulation of microtubule polymerizationGO:003111370.106
segmentationGO:0035282930.106
multicellular organismal agingGO:0010259240.105
Fly
muscle cell differentiationGO:00426922610.105
mitotic cell cycleGO:00002781950.104
regulation of protein localizationGO:00328802310.104
chromosome segregationGO:0007059480.102
blood vessel morphogenesisGO:00485142850.102
single organism nuclear importGO:1902593950.100
g1 s transition of mitotic cell cycleGO:0000082570.099
tube formationGO:00351481400.098
positive regulation of purine nucleotide metabolic processGO:19005441140.098
Human Fly
rna localizationGO:0006403230.097
Human
synapse assemblyGO:0007416560.095
single organismal cell cell adhesionGO:00163371310.093
regulation of actin filament based processGO:0032970990.093
Human
skeletal system developmentGO:00015013560.093
actin filament bundle assemblyGO:0051017400.092
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.090
apoptotic signaling pathwayGO:00971903060.090
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.090
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.089
negative regulation of nervous system developmentGO:00519611560.089
negative regulation of lymphocyte activationGO:0051250910.089
intrinsic apoptotic signaling pathwayGO:00971931320.087
odontogenesis of dentin containing toothGO:0042475660.087
digestive system developmentGO:00551232000.085
intra s dna damage checkpointGO:003157340.083
protein transport within lipid bilayerGO:003259450.082
lens development in camera type eyeGO:0002088620.082
regulation of map kinase activityGO:00434051200.082
cellular response to hypoxiaGO:0071456170.081
Fly
positive regulation of cytoskeleton organizationGO:0051495490.081
phosphatidylinositol mediated signalingGO:0048015410.081
regionalizationGO:00030023370.080
schwann cell proliferationGO:001401020.079
establishment of protein localization to plasma membraneGO:0090002340.079
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.079
cellular response to growth factor stimulusGO:00713631970.078
insulin like growth factor receptor signaling pathwayGO:0048009210.078
regulation of protein serine threonine kinase activityGO:00719001570.078
nuclear transportGO:00511691390.078
Human
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251810.078
cellular amino acid metabolic processGO:00065201030.078
macromolecule methylationGO:00434141200.078
regulation of neural precursor cell proliferationGO:2000177700.077
regulation of protein transportGO:00512231630.077
negative regulation of mitotic cell cycleGO:0045930580.076
oocyte developmentGO:0048599330.076
mesoderm developmentGO:00074981000.076
intracellular mrna localizationGO:000829840.075
methylationGO:00322591340.075
morphogenesis of embryonic epitheliumGO:00163311590.074
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.074
regulation of stress fiber assemblyGO:0051492150.074
Human
inositol lipid mediated signalingGO:0048017410.073
single organism cell adhesionGO:00986021560.073
negative regulation of intracellular signal transductionGO:19025321670.073
Human Fly
positive regulation of macroautophagyGO:001623930.071
phosphatidylinositol 3 kinase signalingGO:0014065360.071
t cell differentiationGO:00302171740.071
regulation of nucleocytoplasmic transportGO:0046822730.070
protein targetingGO:00066051430.070
regulation of leukocyte differentiationGO:19021051590.070
positive regulation of microtubule polymerizationGO:003111630.069
maternal determination of anterior posterior axis embryoGO:000835820.069
oxidation reduction processGO:00551143420.069
cell agingGO:0007569350.069
axonogenesisGO:00074092740.069
regulation of cellular amino acid metabolic processGO:000652150.069
digestive tract morphogenesisGO:00485461470.069
meiotic cytokinesisGO:003320650.066
cellular macromolecule catabolic processGO:00442652060.066
regulation of synapse assemblyGO:0051963290.066
regulation of cell adhesionGO:00301551540.065
Human
cell junction organizationGO:0034330770.065
Human
regulation of cell morphogenesis involved in differentiationGO:00107691510.064
establishment or maintenance of cytoskeleton polarityGO:003095220.064
regulation of cellular response to insulin stimulusGO:1900076300.064
Fly
signal transduction involved in mitotic dna damage checkpointGO:190240230.063
mesoderm morphogenesisGO:0048332640.063
inflammatory responseGO:00069542440.063
organonitrogen compound biosynthetic processGO:19015661920.063
maintenance of locationGO:0051235890.062
regulation of cytoskeleton organizationGO:00514931220.062
Human
camera type eye developmentGO:00430102660.061
striated muscle tissue developmentGO:00147062930.061
embryonic skeletal system developmentGO:00487061200.061
regulation of response to drugGO:200102320.060
response to oxidative stressGO:00069791230.060
regulation of neuron differentiationGO:00456642810.060
t cell activationGO:00421102890.058
organelle localizationGO:00516401790.057
cytokinesisGO:0000910170.056
skin developmentGO:00435882200.056
regulation of hydrolase activityGO:00513362460.056
Human Fly
peptidyl tyrosine modificationGO:00182121450.055
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.054
engulfment of apoptotic cellGO:004365230.054
regulation of neuron apoptotic processGO:00435231220.054
cellular response to external stimulusGO:0071496880.054
regulation of membrane potentialGO:00423911920.053
negative regulation of cell developmentGO:00107211690.053
regulation of cellular response to growth factor stimulusGO:0090287820.053
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.052
regulation of cellular ketone metabolic processGO:0010565660.052
cell cell junction organizationGO:0045216720.052
Human
regulation of organelle organizationGO:00330432890.052
Human
cation transportGO:00068123990.052
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.052
regulation of jak stat cascadeGO:0046425340.051
regulation of protein localization to nucleusGO:1900180600.051
gland developmentGO:00487323300.050
generation of precursor metabolites and energyGO:00060911030.050
positive regulation of cellular amine metabolic processGO:003324050.049
cellular protein complex assemblyGO:00436231160.049
hippocampus developmentGO:0021766520.049
regulation of canonical wnt signaling pathwayGO:0060828820.048
regulation of apoptotic signaling pathwayGO:20012331970.048
actin cytoskeleton organizationGO:00300362200.048
Human
spermatogenesisGO:00072832840.047
negative regulation of nuclear divisionGO:0051784190.047
negative regulation of immune system processGO:00026832090.047
negative regulation of cell cycle processGO:0010948690.047
negative regulation of t cell activationGO:0050868650.047
microtubule cytoskeleton organizationGO:00002261570.046
meiotic cell cycleGO:00513211220.046
cellular response to decreased oxygen levelsGO:0036294180.046
Fly
jak stat cascadeGO:0007259420.045
regulation of cell cycle processGO:00105641600.045
dendrite developmentGO:00163581150.045
digestive tract developmentGO:00485651900.045
axon guidanceGO:00074111410.044
negative regulation of cell divisionGO:0051782240.044
regulation of nuclear divisionGO:0051783560.044
cellular response to starvationGO:0009267570.044
protein polymerizationGO:0051258570.044
regulation of cell cycle phase transitionGO:1901987770.044
protein catabolic processGO:00301632210.044
sensory perception of soundGO:0007605970.043
epidermis developmentGO:00085441870.043
proteolysis involved in cellular protein catabolic processGO:00516031470.043
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.043
organelle assemblyGO:00709251770.042
regulation of neuron projection developmentGO:00109751690.042
myeloid cell homeostasisGO:00022621140.042
lung developmentGO:00303241640.042
regulation of nucleotide biosynthetic processGO:0030808340.042
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.041
negative regulation of cell cycle phase transitionGO:1901988480.041
positive regulation of cellular component biogenesisGO:0044089940.041
Human
circadian rhythmGO:00076231140.041
positive chemotaxisGO:0050918180.041
glial cell apoptotic processGO:003434930.041
regulation of system processGO:00440572000.041
positive regulation of cellular amino acid metabolic processGO:004576430.040
regulation of actin filament bundle assemblyGO:0032231180.040
Human
microtubule based processGO:00070172360.040
cellular response to oxidative stressGO:0034599760.039
protein methylationGO:0006479810.039
somitogenesisGO:0001756690.039
establishment or maintenance of cell polarityGO:0007163860.039
sensory perceptionGO:00076002450.039
dna integrity checkpointGO:0031570280.038
ectoderm developmentGO:0007398150.038
regulation of cellular response to stressGO:00801351590.038
organic acid biosynthetic processGO:0016053860.038
erythrocyte differentiationGO:0030218880.038
regulation of t cell differentiationGO:0045580830.038
nucleotide excision repairGO:0006289130.037
regulation of gliogenesisGO:0014013500.037
gene silencingGO:0016458380.037
negative regulation of organelle organizationGO:0010639900.037
protein processingGO:00164851630.037
regulation of protein import into nucleusGO:0042306520.037
histone lysine methylationGO:0034968500.037
multicellular organismal signalingGO:0035637910.037
muscle cell developmentGO:00550011330.037
ossificationGO:00015032160.036
nucleoside phosphate biosynthetic processGO:1901293790.036
dna modificationGO:0006304500.036
cellular homeostasisGO:00197252400.036
apical protein localizationGO:004517670.036
regulation of cell motilityGO:20001452360.036
syncytium formation by plasma membrane fusionGO:0000768420.036
regulation of lymphocyte differentiationGO:00456191070.036
regulation of peptidyl tyrosine phosphorylationGO:0050730930.036
positive regulation of programmed cell deathGO:00430682180.036
signal transduction involved in dna damage checkpointGO:007242230.036
mesenchyme developmentGO:00604851520.035
regulation of cell projection organizationGO:00313442060.035
macroautophagyGO:0016236210.035
rhythmic processGO:00485111740.035
positive regulation of cell developmentGO:00107202370.035
regulation of intracellular transportGO:00323861590.035
macromolecule catabolic processGO:00090572810.035
histone methylationGO:0016571710.035
cellular lipid metabolic processGO:00442553230.034
establishment or maintenance of bipolar cell polarityGO:0061245210.034
gastrulationGO:00073691160.034
myeloid leukocyte differentiationGO:00025731190.034
regulation of dna replicationGO:0006275170.034
negative regulation of mammary gland epithelial cell proliferationGO:003360030.034
cell adhesionGO:00071553290.033
Human
regulation of protein complex assemblyGO:0043254830.033
regulation of lymphocyte activationGO:00512492400.033
neuron deathGO:00709971540.033
dna damage response signal transduction by p53 class mediatorGO:0030330190.033
leukocyte differentiationGO:00025213420.033
activation of adenylate cyclase activityGO:000719040.033
cell cycle arrestGO:0007050370.033
energy derivation by oxidation of organic compoundsGO:0015980770.033
fatty acid biosynthetic processGO:0006633410.032
negative regulation of ligase activityGO:005135230.032
cellular response to lipidGO:00713961450.032
signal transduction by p53 class mediatorGO:0072331510.032
mitotic g1 dna damage checkpointGO:003157140.032
regulation of blood pressureGO:0008217930.032
protein maturationGO:00516041760.032
positive regulation of smooth muscle cell migrationGO:001491140.032
carbohydrate derivative biosynthetic processGO:19011371830.032
organophosphate biosynthetic processGO:00904071220.032
regulation of lymphocyte proliferationGO:00506701170.031
ion transmembrane transportGO:00342203610.031
mitotic sister chromatid separationGO:005130690.031
cohesin localization to chromatinGO:007192110.031
dna replicationGO:0006260520.031
myotube differentiationGO:00149021050.031
immune response activating signal transductionGO:00027571160.030
positive regulation of microtubule polymerization or depolymerizationGO:003111230.030
cellular response to oxygen levelsGO:0071453200.030
Fly
somatic stem cell maintenanceGO:0035019470.030
chromatin organizationGO:00063252060.030
regulation of cytoplasmic transportGO:19036491120.030
regulation of ras gtpase activityGO:0032318880.030
Human Fly
negative regulation of mitotic cell cycle phase transitionGO:1901991450.030
negative regulation of fibroblast migrationGO:001076420.030
monocarboxylic acid metabolic processGO:00327871910.030
positive regulation of mitotic cell cycleGO:0045931410.030
positive regulation of kinase activityGO:00336741550.030
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.030
peptidyl tyrosine phosphorylationGO:00181081430.030
response to growth factorGO:00708481980.029
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.029
regulation of ion transportGO:00432692150.029
anatomical structure homeostasisGO:00602491450.029
regulation of macroautophagyGO:0016241120.029
regulation of feeding behaviorGO:006025930.029
gliogenesisGO:00420631410.029
ribonucleotide biosynthetic processGO:0009260590.029
negative regulation of lymphocyte differentiationGO:0045620320.029
positive regulation of rap gtpase activityGO:003285430.029
negative regulation of rac protein signal transductionGO:003502140.029
forebrain developmentGO:00309003020.028
g protein coupled receptor signaling pathwayGO:00071862430.028
purine containing compound biosynthetic processGO:0072522700.028
formation of primary germ layerGO:0001704770.028
establishment of protein localization to membraneGO:0090150540.028
regulation of cell migrationGO:00303342190.028
embryonic axis specificationGO:0000578300.028
positive regulation of protein catabolic processGO:0045732600.028
regulation of cohesin localization to chromatinGO:007192210.028
positive regulation of protein export from nucleusGO:004682740.028
camp biosynthetic processGO:0006171310.027
heart morphogenesisGO:00030071780.027
positive regulation of apoptotic signaling pathwayGO:2001235950.027

Tsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.338
cancerDOID:16200.133
organ system cancerDOID:005068600.133
intestinal cancerDOID:1015500.055
gastrointestinal system cancerDOID:311900.055
colon cancerDOID:21900.055
colorectal cancerDOID:925600.055
large intestine cancerDOID:567200.055
disease of metabolismDOID:001466700.045
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.040
benign neoplasmDOID:006007200.037
thoracic cancerDOID:509300.029