Mus musculus

87 known processes

Topors

topoisomerase I binding, arginine/serine-rich

(Aliases: TP53BPL,AW105885,LUN,p53BP3/LUN)

Topors biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic signaling pathwayGO:00971903060.086
male gamete generationGO:00482322850.082
cellular ketone metabolic processGO:0042180840.058
response to radiationGO:00093141650.056
cellular amine metabolic processGO:0044106440.054
amine metabolic processGO:0009308450.050
regulation of organelle organizationGO:00330432890.048
negative regulation of molecular functionGO:00440922580.047
nucleotide metabolic processGO:00091173320.045
regulation of apoptotic signaling pathwayGO:20012331970.043
organonitrogen compound catabolic processGO:19015652640.042
spermatogenesisGO:00072832840.041
regulation of cellular response to stressGO:00801351590.041
positive regulation of programmed cell deathGO:00430682180.040
organophosphate catabolic processGO:00464342320.038
organelle fissionGO:00482851700.037
Fly
protein localization to organelleGO:00333651850.036
Human
positive regulation of apoptotic signaling pathwayGO:2001235950.036
meiotic nuclear divisionGO:00071261150.035
Fly
regulation of cellular ketone metabolic processGO:0010565660.035
purine ribonucleotide metabolic processGO:00091502900.034
glycosyl compound catabolic processGO:19016582060.034
regulation of cellular amine metabolic processGO:0033238200.034
cellular response to dna damage stimulusGO:00069742070.034
ribonucleoside metabolic processGO:00091192450.033
cellular amino acid metabolic processGO:00065201030.033
ribose phosphate metabolic processGO:00196932910.031
transmission of nerve impulseGO:0019226760.031
regulation of cellular component biogenesisGO:00440871810.030
protein modification by small protein conjugation or removalGO:00706472070.030
Human Fly
positive regulation of cell deathGO:00109422240.030
positive regulation of apoptotic processGO:00430652170.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
regulation of synaptic growth at neuromuscular junctionGO:000858240.030
nucleobase containing small molecule metabolic processGO:00550863520.029
nuclear divisionGO:00002801580.029
Fly
ion transmembrane transportGO:00342203610.029
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.028
negative regulation of cellular amino acid metabolic processGO:004576300.028
ribonucleoside catabolic processGO:00424542060.028
mitotic cell cycle processGO:19030471590.028
Fly
protein localization to nucleusGO:00345041210.026
Human
germ cell developmentGO:00072811850.026
glycosyl compound metabolic processGO:19016572460.026
multicellular organismal signalingGO:0035637910.026
skeletal system developmentGO:00015013560.025
regulation of cellular catabolic processGO:00313292420.025
ossificationGO:00015032160.025
regulation of protein complex assemblyGO:0043254830.024
regulation of cellular amino acid metabolic processGO:000652150.024
gene silencingGO:0016458380.024
posttranscriptional regulation of gene expressionGO:00106081550.024
dna metabolic processGO:00062593030.024
Fly
positive regulation of cellular amine metabolic processGO:003324050.024
regulation of membrane potentialGO:00423911920.024
mitotic cell cycleGO:00002781950.024
Fly
negative regulation of cell proliferationGO:00082852960.024
protein ubiquitinationGO:00165671710.024
Human Fly
negative regulation of protein metabolic processGO:00512482820.024
hematopoietic progenitor cell differentiationGO:00022441430.023
response to light stimulusGO:00094161350.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
single organism nuclear importGO:1902593950.022
regulation of hydrolase activityGO:00513362460.022
membrane organizationGO:00610242450.022
Fly
purine nucleotide metabolic processGO:00061633020.022
ribonucleotide catabolic processGO:00092612080.022
regulation of bindingGO:00510981110.022
action potentialGO:0001508780.021
carbohydrate derivative catabolic processGO:19011362310.021
intracellular mrna localizationGO:000829840.021
blastocyst developmentGO:0001824800.021
negative regulation of cellular amine metabolic processGO:003323910.021
leukocyte differentiationGO:00025213420.021
homeostasis of number of cellsGO:00488722100.021
cell divisionGO:00513011200.021
organic hydroxy compound metabolic processGO:19016152030.021
cellular nitrogen compound catabolic processGO:00442702800.021
ribonucleoside triphosphate catabolic processGO:00092031990.020
cellular response to gamma radiationGO:007148040.020
neural tube developmentGO:00219151600.020
organelle assemblyGO:00709251770.020
spermatid differentiationGO:00485151150.020
neuronal action potentialGO:0019228540.020
positive regulation of nervous system developmentGO:00519622210.020
negative regulation of immune system processGO:00026832090.020
microtubule cytoskeleton organizationGO:00002261570.020
Fly
myeloid cell differentiationGO:00300992330.020
nucleoside triphosphate metabolic processGO:00091412300.019
ribonucleotide metabolic processGO:00092592910.019
purine ribonucleoside catabolic processGO:00461302050.019
gene silencing by rnaGO:0031047190.019
nucleoside phosphate metabolic processGO:00067533380.019
chromatin silencing at rdnaGO:000018330.019
myeloid leukocyte differentiationGO:00025731190.019
epithelial tube formationGO:00721751300.019
positive regulation of cell cycle processGO:0090068610.019
regulation of cell activationGO:00508652890.019
regulation of cell cycle processGO:00105641600.018
Fly
positive regulation of organelle organizationGO:00106381280.018
regulation of response to woundingGO:19030341890.018
dna repairGO:00062811070.018
response to acid chemicalGO:00011011110.018
regulation of protein kinase activityGO:00458592320.018
negative regulation of cell cycleGO:00457861230.018
Fly
cellular response to radiationGO:0071478280.018
cellular lipid metabolic processGO:00442553230.018
regulation of mitotic cell cycleGO:00073461260.018
Fly
gland developmentGO:00487323300.018
purine ribonucleoside triphosphate metabolic processGO:00092052200.018
transmembrane transportGO:00550854120.017
tube formationGO:00351481400.017
purine ribonucleotide catabolic processGO:00091542080.017
purine nucleotide catabolic processGO:00061952110.017
male meiosis iGO:0007141160.017
negative regulation of cellular protein metabolic processGO:00322692470.017
nuclear importGO:0051170950.017
camera type eye developmentGO:00430102660.017
aromatic compound catabolic processGO:00194392860.017
rna interferenceGO:001624620.017
regulation of ossificationGO:00302781120.017
nucleoside phosphate catabolic processGO:19012922220.017
purine ribonucleoside metabolic processGO:00461282410.017
placenta developmentGO:00018901400.017
negative regulation of protein processingGO:0010955790.016
posttranscriptional gene silencingGO:0016441100.016
purine nucleoside catabolic processGO:00061522050.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
organic cyclic compound catabolic processGO:19013612950.016
nucleoside monophosphate metabolic processGO:0009123850.016
developmental maturationGO:00217001930.016
regulation of lymphocyte activationGO:00512492400.016
myelinationGO:0042552740.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
respiratory system developmentGO:00605411900.016
purine containing compound catabolic processGO:00725232130.016
oocyte axis specificationGO:000730920.016
negative regulation of intracellular signal transductionGO:19025321670.016
regulation of cell cycleGO:00517262810.016
Fly
positive regulation of hydrolase activityGO:00513451480.015
bone developmentGO:00603481200.015
peptidyl amino acid modificationGO:00181933360.015
dephosphorylationGO:00163111290.015
compound eye developmentGO:004874910.015
epithelial tube morphogenesisGO:00605623030.015
regulation of purine nucleotide metabolic processGO:19005421690.015
forebrain developmentGO:00309003020.015
protein import into nucleusGO:0006606950.015
protein importGO:00170381010.015
nucleoside catabolic processGO:00091642060.015
lymphocyte differentiationGO:00300982420.015
b cell activationGO:00421131610.015
microtubule based processGO:00070172360.015
Fly
ensheathment of neuronsGO:0007272760.015
positive regulation of protein modification processGO:00314012990.015
Human
ribonucleoside triphosphate metabolic processGO:00091992200.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
axon ensheathmentGO:0008366760.015
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.015
erythrocyte differentiationGO:0030218880.014
cation transportGO:00068123990.014
regulation of defense responseGO:00313472330.014
circulatory system processGO:00030131970.014
heterochromatin organizationGO:007082840.014
immune effector processGO:00022523210.014
epithelial cell developmentGO:00020641590.014
male sex differentiationGO:00466611090.014
regulation of nucleotide metabolic processGO:00061401690.014
cytoplasmic transportGO:00164822340.014
positive regulation of cell developmentGO:00107202370.014
nucleoside triphosphate catabolic processGO:00091432050.014
negative regulation of protein modification processGO:00314001630.014
regulation of protein localizationGO:00328802310.014
protein acylationGO:0043543640.014
regulation of transferase activityGO:00513382630.014
Human
chromatin organizationGO:00063252060.014
heterocycle catabolic processGO:00467002800.014
respiratory tube developmentGO:00303231670.014
regulation of transcription by chromatin organizationGO:003440100.014
cation transmembrane transportGO:00986552660.014
development of primary sexual characteristicsGO:00451371430.013
mitotic nuclear divisionGO:0007067480.013
cell type specific apoptotic processGO:00972852680.013
muscle cell differentiationGO:00426922610.013
regulation of leukocyte differentiationGO:19021051590.013
cellular response to lipidGO:00713961450.013
muscle tissue developmentGO:00605373080.013
carbohydrate metabolic processGO:00059752300.013
modification dependent protein catabolic processGO:00199411330.013
Human Fly
production of molecular mediator of immune responseGO:00024401030.013
purine nucleoside metabolic processGO:00422782410.013
regulation of cell divisionGO:0051302760.013
intestinal epithelial structure maintenanceGO:006072940.013
chromatin modificationGO:00165681870.013
embryonic epithelial tube formationGO:00018381300.013
gonad developmentGO:00084061410.013
establishment of protein localization to organelleGO:00725941180.013
nucleotide catabolic processGO:00091662170.013
protein maturationGO:00516041760.013
positive regulation of cell cycleGO:0045787920.013
regulation of system processGO:00440572000.013
protein processingGO:00164851630.013
anatomical structure homeostasisGO:00602491450.013
regulation of neuron projection developmentGO:00109751690.013
nucleoside metabolic processGO:00091162460.013
chromosome segregationGO:0007059480.013
Fly
cell maturationGO:00484691270.013
cellular response to cytokine stimulusGO:00713451890.013
morphogenesis of embryonic epitheliumGO:00163311590.013
response to growth factorGO:00708481980.013
multicellular organismal homeostasisGO:00488711640.013
cellular response to abiotic stimulusGO:0071214560.012
protein modification by small protein conjugationGO:00324461870.012
Human Fly
striated muscle tissue developmentGO:00147062930.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
regulation of nuclear divisionGO:0051783560.012
regulation of cell projection organizationGO:00313442060.012
lateral inhibitionGO:004633110.012
macromolecule catabolic processGO:00090572810.012
Human Fly
nuclear transportGO:00511691390.012
intracellular protein transportGO:00068862040.012
negative regulation of phosphate metabolic processGO:00459361840.012
rna splicingGO:0008380540.012
spermatid developmentGO:00072861080.012
regulation of kinase activityGO:00435492490.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
regionalizationGO:00030023370.012
positive regulation of cellular component biogenesisGO:0044089940.012
regulation of chromosome organizationGO:0033044830.012
regulation of cytokine productionGO:00018172660.012
neural tube formationGO:00018411080.011
positive regulation of protein phosphorylationGO:00019342420.011
response to organic cyclic compoundGO:00140701980.011
negative regulation of dna replicationGO:000815640.011
meiotic cell cycle processGO:1903046770.011
Fly
connective tissue developmentGO:00614481790.011
gliogenesisGO:00420631410.011
retina development in camera type eyeGO:00600411190.011
cellular homeostasisGO:00197252400.011
inorganic cation transmembrane transportGO:00986622070.011
regulation of secretion by cellGO:19035302490.011
divalent inorganic cation transportGO:00725111780.011
purine containing compound metabolic processGO:00725213110.011
negative regulation of neuron differentiationGO:00456651010.011
atp catabolic processGO:0006200550.011
response to uvGO:0009411440.011
skin developmentGO:00435882200.011
regulation of cell cycle phase transitionGO:1901987770.011
Fly
fat cell differentiationGO:00454441600.011
cytokine productionGO:00018163190.011
positive regulation of protein kinase activityGO:00458601440.011
skeletal system morphogenesisGO:00487052030.011
regulation of response to dna damage stimulusGO:2001020340.011
regulation of proteolysisGO:00301621640.011
covalent chromatin modificationGO:00165691630.011
inorganic ion transmembrane transportGO:00986602340.011
regulation of chromatin organizationGO:1902275570.011
nucleocytoplasmic transportGO:00069131390.010
protein oligomerizationGO:0051259670.010
small molecule biosynthetic processGO:00442831320.010
blood circulationGO:00080151950.010
reactive oxygen species metabolic processGO:0072593840.010
g protein coupled receptor signaling pathwayGO:00071862430.010
cellular chemical homeostasisGO:00550822150.010
purine nucleoside monophosphate catabolic processGO:0009128580.010
positive regulation of growthGO:00459271040.010
regulation of establishment of protein localizationGO:00702011810.010
multicellular organism growthGO:00352641610.010
b cell differentiationGO:0030183780.010
modification dependent macromolecule catabolic processGO:00436321330.010
Human Fly
positive regulation of mitotic cell cycleGO:0045931410.010
nitrogen compound transportGO:00717052710.010
regulation of protein maturationGO:1903317960.010
inflammatory responseGO:00069542440.010

Topors disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
Human
nervous system diseaseDOID:86300.012
Human
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011