Mus musculus

38 known processes

Spp1

secreted phosphoprotein 1

(Aliases: BSPI,Apl-1,ETA-1,Opnl,Bsp,Spp-1,Eta,2AR,BNSP,Opn,Ric,OP)

Spp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of molecule of bacterial originGO:003249020.836
innate immune response activating cell surface receptor signaling pathwayGO:000222040.808
regulation of response to woundingGO:19030341890.712
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.696
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.682
modulation by symbiont of defense related host nitric oxide productionGO:005216310.653
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.607
interleukin 18 mediated signaling pathwayGO:003565520.606
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.587
regulation of inflammatory responseGO:00507271470.581
cellular amine metabolic processGO:0044106440.563
cellular response to interleukin 18GO:007135130.534
response to molecule of fungal originGO:000223840.519
regulation of defense responseGO:00313472330.513
neuronal action potentialGO:0019228540.507
response to host immune responseGO:005257230.504
response to defense related host nitric oxide productionGO:005256520.470
cellular response to peptidoglycanGO:007122440.469
regulation of membrane potentialGO:00423911920.468
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.455
organic acid transportGO:00158491010.431
response to bacterial lipoproteinGO:003249340.431
positive regulation of response to woundingGO:1903036660.416
response to lipopolysaccharideGO:00324961280.395
transmission of nerve impulseGO:0019226760.394
axon ensheathmentGO:0008366760.394
modulation by symbiont of host immune responseGO:005255310.381
positive regulation of cellular amino acid metabolic processGO:004576430.380
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.375
amine metabolic processGO:0009308450.367
positive regulation of inflammatory responseGO:0050729470.363
peptide transportGO:00158331330.362
regulation of cellular ketone metabolic processGO:0010565660.359
response to molecule of bacterial originGO:00022371430.356
positive regulation of macrophage cytokine productionGO:006090770.347
regulation of acute inflammatory responseGO:0002673270.344
interferon beta biosynthetic processGO:004535040.341
myelinationGO:0042552740.331
action potentialGO:0001508780.329
positive regulation of programmed cell deathGO:00430682180.329
response to immune response of other organism involved in symbiotic interactionGO:005256430.327
positive regulation of cellular amine metabolic processGO:003324050.314
response to organic cyclic compoundGO:00140701980.314
regulation of cellular amine metabolic processGO:0033238200.312
positive regulation by symbiont of host immune responseGO:005255610.312
leukocyte differentiationGO:00025213420.311
negative regulation of interleukin 17 productionGO:003270050.305
carboxylic acid transportGO:00469421000.304
modification by symbiont of host morphology or physiologyGO:004400340.301
cellular response to molecule of bacterial originGO:0071219830.295
regulation of cell activationGO:00508652890.295
defense response to other organismGO:00985421970.295
negative regulation of inflammatory responseGO:0050728610.293
cytokine mediated signaling pathwayGO:00192211150.290
positive regulation of interleukin 18 productionGO:003274120.289
wound healing involved in inflammatory responseGO:000224640.284
response to host defensesGO:005220030.283
anion transportGO:00068201770.283
positive regulation of reactive oxygen species biosynthetic processGO:190342820.282
response to oxygen levelsGO:0070482620.279
cell type specific apoptotic processGO:00972852680.279
regulation of reactive oxygen species biosynthetic processGO:190342620.276
regulation of ion transportGO:00432692150.274
positive regulation of defense responseGO:00313491240.274
cellular ion homeostasisGO:00068731650.267
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.267
multicellular organismal signalingGO:0035637910.266
induction by symbiont of host immune responseGO:005255910.262
inflammatory response to woundingGO:009059440.261
positive regulation of production of molecular mediator of immune responseGO:0002702450.254
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005226310.247
cellular lipid metabolic processGO:00442553230.240
response to hostGO:007513630.240
positive regulation of reactive oxygen species metabolic processGO:2000379110.237
organic anion transportGO:00157111370.237
positive regulation of leukocyte proliferationGO:0070665730.237
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.234
inflammatory responseGO:00069542440.233
regulation of cytokine production involved in immune responseGO:0002718260.228
angiogenesisGO:00015252010.227
leukocyte migrationGO:00509001240.226
cytokine productionGO:00018163190.220
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.215
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.215
nitric oxide production involved in inflammatory responseGO:000253720.214
cellular response to lipidGO:00713961450.213
cation homeostasisGO:00550802120.208
regulation of leukocyte proliferationGO:00706631210.208
positive regulation of secretionGO:00510471300.208
cellular response to oxidative stressGO:0034599760.205
positive regulation of apoptotic cell clearanceGO:200042730.202
regulation of b cell activationGO:0050864810.202
b cell proliferationGO:0042100530.199
negative regulation of response to woundingGO:1903035770.198
metal ion homeostasisGO:00550651890.192
positive regulation of lymphocyte proliferationGO:0050671700.192
cellular amino acid metabolic processGO:00065201030.190
regulation of secretionGO:00510462740.189
blood vessel morphogenesisGO:00485142850.188
negative regulation of interleukin 6 productionGO:0032715170.187
regulation of mapk cascadeGO:00434082480.187
cellular chemical homeostasisGO:00550822150.187
response to low density lipoprotein particleGO:005509820.186
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.185
positive regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042620.184
regulation of mhc class ii biosynthetic processGO:004534670.184
lipid biosynthetic processGO:00086101790.184
antibiotic transportGO:004289110.183
acute inflammatory responseGO:0002526410.181
interleukin 18 productionGO:003262140.181
regulation of cytokine productionGO:00018172660.180
regulation of lymphocyte activationGO:00512492400.178
b cell activationGO:00421131610.177
positive regulation of acute inflammatory responseGO:0002675160.175
fatty acid metabolic processGO:00066311210.174
nitrogen compound transportGO:00717052710.174
induction by organism of defense response of other organism involved in symbiotic interactionGO:005225110.174
organic hydroxy compound metabolic processGO:19016152030.173
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.173
positive regulation of cytokine production involved in immune responseGO:0002720190.171
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.170
leukocyte apoptotic processGO:0071887710.169
eosinophil activation involved in immune responseGO:000227810.168
reactive nitrogen species metabolic processGO:200105700.167
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.165
cellular response to organonitrogen compoundGO:00714171450.165
cellular ketone metabolic processGO:0042180840.164
response to organonitrogen compoundGO:00102432460.163
response to inorganic substanceGO:0010035960.163
ensheathment of neuronsGO:0007272760.161
cellular response to bacterial lipopeptideGO:007122130.159
myeloid cell differentiationGO:00300992330.154
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.154
response to oxidative stressGO:00069791230.153
extracellular matrix organizationGO:00301981470.152
negative regulation of defense responseGO:0031348770.151
wound healingGO:00420601570.150
antibacterial peptide productionGO:000277820.150
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.149
negative regulation of cytokine productionGO:0001818840.148
cellular response to bacterial lipoproteinGO:007122030.148
peptidyl amino acid modificationGO:00181933360.148
macrophage cytokine productionGO:001093490.144
regulation of apoptotic signaling pathwayGO:20012331970.143
positive regulation by symbiont of host defense responseGO:005250910.143
positive regulation of map kinase activityGO:0043406840.142
regulation of membrane protein ectodomain proteolysisGO:005104330.142
positive regulation of protein modification processGO:00314012990.142
response to defenses of other organism involved in symbiotic interactionGO:005217330.141
regulation of cellular amino acid metabolic processGO:000652150.141
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.140
positive regulation of protein secretionGO:0050714520.137
positive regulation of membrane protein ectodomain proteolysisGO:005104430.136
positive regulation of t cell costimulationGO:200052520.136
regulation of interleukin 18 productionGO:003266130.135
extracellular structure organizationGO:00430621480.134
t cell extravasationGO:007268340.133
cellular response to biotic stimulusGO:0071216920.132
positive regulation of apoptotic processGO:00430652170.131
regulation of sequence specific dna binding transcription factor activityGO:00510901060.131
ossificationGO:00015032160.130
negative regulation of chemokine biosynthetic processGO:004507920.129
protein kinase b signalingGO:0043491740.128
oxidation reduction processGO:00551143420.128
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.127
response to vitamin aGO:003318910.124
regulation of protein localizationGO:00328802310.124
fever generationGO:000166070.123
transmembrane transportGO:00550854120.122
negative regulation of cell proliferationGO:00082852960.122
regulation of cellular response to stressGO:00801351590.121
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.121
tyrosine phosphorylation of stat1 proteinGO:004250830.120
regulation of protein secretionGO:0050708820.119
positive regulation of lymphocyte activationGO:00512511400.118
peptide secretionGO:00027901140.116
interleukin 10 secretionGO:007260840.116
positive regulation of interleukin 6 productionGO:0032755370.115
negative regulation of chemokine productionGO:003268240.115
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.115
immune effector processGO:00022523210.114
amide transportGO:00428861380.113
positive regulation of intracellular transportGO:0032388700.113
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.112
positive regulation of b cell proliferationGO:0030890240.112
regulation of interleukin 6 productionGO:0032675550.112
positive regulation of protein phosphorylationGO:00019342420.111
regulation of kinase activityGO:00435492490.111
regulation of cell motilityGO:20001452360.110
epidermis developmentGO:00085441870.110
protein secretionGO:00093061110.108
regulation of neuron apoptotic processGO:00435231220.108
neuron deathGO:00709971540.108
apoptotic signaling pathwayGO:00971903060.107
positive regulation of secretion by cellGO:19035321140.106
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.105
chemokine productionGO:0032602340.105
immune complex clearance by monocytes and macrophagesGO:000243620.104
regulation of peptide transportGO:0090087910.103
positive regulation of cell migrationGO:00303351090.102
microglial cell activation involved in immune responseGO:000228210.102
eosinophil degranulationGO:004330810.101
regulation of inflammatory response to antigenic stimulusGO:0002861210.100
response to interleukin 1GO:0070555110.100
positive regulation of cell activationGO:00508671580.100
induction by symbiont of defense related host nitric oxide productionGO:005206310.100
cell activation involved in immune responseGO:00022631260.099
peptidyl serine modificationGO:0018209830.099
calcium ion homeostasisGO:00550741270.099
response to bacterial lipopeptideGO:007033930.097
positive regulation of hemostasisGO:1900048100.097
reactive oxygen species metabolic processGO:0072593840.097
positive regulation of glial cell proliferationGO:006025240.097
production of molecular mediator involved in inflammatory responseGO:0002532210.097
leukocyte activation involved in immune responseGO:00023661260.097
monocarboxylic acid transportGO:0015718440.096
interaction with hostGO:0051701220.096
purine nucleoside biosynthetic processGO:0042451190.096
extrinsic apoptotic signaling pathwayGO:00971911260.095
dna metabolic processGO:00062593030.095
monocarboxylic acid metabolic processGO:00327871910.095
acylglycerol metabolic processGO:0006639550.095
positive regulation of cytokine productionGO:00018191740.094
t cell activationGO:00421102890.094
neutrophil apoptotic processGO:000178130.094
positive regulation of dendritic cell chemotaxisGO:200051010.094
regulation of peptidase activityGO:0052547960.094
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108190.094
i kappab kinase nf kappab signalingGO:0007249850.094
cell surface pattern recognition receptor signaling pathwayGO:000275220.094
positive regulation of cell developmentGO:00107202370.093
reactive oxygen species biosynthetic processGO:190340980.093
cellular divalent inorganic cation homeostasisGO:00725031270.093
interleukin 5 secretionGO:007260320.093
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.093
divalent inorganic cation homeostasisGO:00725071380.092
regulation of cytokine secretionGO:0050707610.092
regulation of interleukin 6 biosynthetic processGO:0045408110.092
eosinophil activationGO:004330710.092
response to glucocorticoidGO:0051384200.092
regulation of t cell costimulationGO:200052320.091
cellular response to cytokine stimulusGO:00713451890.091
regulation of interleukin 10 secretionGO:200117940.091
chemokine mediated signaling pathwayGO:0070098170.091
sensory perceptionGO:00076002450.090
lymphocyte activation involved in immune responseGO:0002285930.090
response to reactive oxygen speciesGO:0000302560.090
negative regulation of secretionGO:0051048610.089
response to extracellular stimulusGO:00099911270.089
positive regulation of protein transportGO:0051222930.089
positive regulation of phagocytosis engulfmentGO:006010030.088
glial cell differentiationGO:00100011310.088
adaptive immune responseGO:00022501550.088
regulation of establishment of protein localizationGO:00702011810.087
lipid homeostasisGO:0055088630.087
positive regulation of protein serine threonine kinase activityGO:00719021060.086
myeloid cell homeostasisGO:00022621140.086
positive regulation of t cell proliferationGO:0042102520.086
regulation of protein transportGO:00512231630.086
regulation of cell migrationGO:00303342190.084
positive regulation of interferon alpha productionGO:003272740.084
nitric oxide synthase biosynthetic processGO:005176770.084
epithelial cell proliferationGO:00506731740.084
positive regulation of cell motilityGO:20001471160.083
cytokine production involved in immune responseGO:0002367340.082
response to hypoxiaGO:0001666580.082
mapk cascadeGO:00001652810.082
positive regulation of cell deathGO:00109422240.082
glial cell apoptotic processGO:003434930.081
gliogenesisGO:00420631410.081
protein catabolic processGO:00301632210.079
response to growth factorGO:00708481980.078
morphogenesis of a branching structureGO:00017632030.078
regulation of secretion by cellGO:19035302490.077
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.076
regulation of vascular endothelial growth factor productionGO:0010574130.076
cellular calcium ion homeostasisGO:00068741190.075
b cell activation involved in immune responseGO:0002312500.075
negative regulation of hydrolase activityGO:0051346710.075
placenta developmentGO:00018901400.074
organ or tissue specific immune responseGO:0002251130.074
lymphocyte homeostasisGO:0002260640.073
leukocyte mediated immunityGO:00024431740.073
defense response to gram positive bacteriumGO:0050830500.072
positive regulation of b cell activationGO:0050871490.072
purine containing compound biosynthetic processGO:0072522700.072
chloramphenicol transportGO:004289210.072
cytokine secretionGO:0050663720.072
cellular response to lipopolysaccharideGO:0071222770.071
regulation of dendritic cell chemotaxisGO:200050810.071
cellular metal ion homeostasisGO:00068751510.071
divalent metal ion transportGO:00708381720.071
response to interleukin 15GO:007067230.070
positive regulation of cytokine secretionGO:0050715410.070
defense response to gram negative bacteriumGO:0050829280.070
positive regulation of neuron projection regenerationGO:007057220.070
response to corticosteroidGO:0031960200.069
response to nutrient levelsGO:00316671090.069
negative regulation of interleukin 23 productionGO:003270710.069
positive regulation of adaptive immune responseGO:0002821610.069
response to acid chemicalGO:00011011110.069
calcium ion transportGO:00068161590.069
regulation of interleukin 8 productionGO:003267730.068
response to drugGO:0042493750.068
positive regulation of platelet activationGO:001057250.067
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.067
positive regulation of fatty acid oxidationGO:004632140.066
myeloid leukocyte cytokine productionGO:0061082120.066
cellular response to external stimulusGO:0071496880.066
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.065
interleukin 6 mediated signaling pathwayGO:007010260.065
negative regulation of macrophage apoptotic processGO:200011030.065
regulation of monocyte extravasationGO:200043720.065
homeostasis of number of cellsGO:00488722100.065
positive regulation of coagulationGO:0050820130.065
response to amino acidGO:0043200370.064
negative regulation of immune system processGO:00026832090.064
carboxylic acid biosynthetic processGO:0046394860.064
myd88 dependent toll like receptor signaling pathwayGO:000275570.064
positive regulation of kinase activityGO:00336741550.064
regulation of cytokine biosynthetic processGO:0042035590.063
carbohydrate homeostasisGO:00335001280.063
positive regulation of interferon beta biosynthetic processGO:004535930.063
oligodendrocyte differentiationGO:0048709530.063
regulation of glial cell differentiationGO:0045685410.063
defense response to bacteriumGO:00427421190.063
response to fatty acidGO:007054280.063
lipopolysaccharide mediated signaling pathwayGO:0031663250.063
ion transmembrane transportGO:00342203610.062
response to increased oxygen levelsGO:003629620.062
macrophage activationGO:0042116270.062
lymphocyte differentiationGO:00300982420.061
macromolecule catabolic processGO:00090572810.061
small molecule biosynthetic processGO:00442831320.061
positive regulation of interleukin 12 productionGO:0032735210.061
regulation of chemokine secretionGO:009019640.061
interleukin 11 mediated signaling pathwayGO:003815420.060
toxin transportGO:1901998380.060
coagulationGO:0050817780.059
intestinal epithelial structure maintenanceGO:006072940.059
regulation of protein kinase activityGO:00458592320.059
negative regulation of interleukin 5 secretionGO:200066310.059
myeloid leukocyte activationGO:0002274830.059
regulation of type 2 immune responseGO:0002828180.059
neuron apoptotic processGO:00514021420.058
positive regulation by organism of immune response of other organism involved in symbiotic interactionGO:005255510.058
sensory perception of painGO:0019233470.058
response to peptide hormoneGO:00434341270.057
multicellular organismal macromolecule metabolic processGO:0044259190.057
immune complex clearanceGO:000243420.057
glucose homeostasisGO:00425931280.057
regulation of transferase activityGO:00513382630.056
odontogenesisGO:0042476780.056
fatty acid transportGO:0015908280.055
regulation of ossificationGO:00302781120.055
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.055
purine nucleobase metabolic processGO:000614440.055
tissue migrationGO:0090130680.055
muscle system processGO:00030121410.055
cellular homeostasisGO:00197252400.054
immunoglobulin productionGO:0002377730.054
response to tumor necrosis factorGO:0034612260.054
regulation of cytokine secretion involved in immune responseGO:000273940.054
nucleobase containing small molecule metabolic processGO:00550863520.054
somatic recombination of immunoglobulin gene segmentsGO:0016447420.054
negative regulation of intracellular signal transductionGO:19025321670.054
regulation of vitamin d biosynthetic processGO:006055610.054
vascular endothelial growth factor productionGO:0010573130.054
bone mineralizationGO:0030282540.053
cellular response to acid chemicalGO:0071229680.053
negative regulation of multicellular organismal metabolic processGO:004425210.053
lymphocyte migrationGO:0072676260.053
nucleoside metabolic processGO:00091162460.053
regulation of b cell proliferationGO:0030888390.053
lipid localizationGO:00108761260.053
ras protein signal transductionGO:0007265770.053
positive regulation of nervous system developmentGO:00519622210.053
positive regulation of homeostatic processGO:0032846640.052
regulation of immunological synapse formationGO:200052020.052
b cell proliferation involved in immune responseGO:000232250.052
cellular response to hexose stimulusGO:0071331470.051
interleukin 6 productionGO:0032635580.051
interleukin 33 mediated signaling pathwayGO:003817210.051
negative regulation of erk1 and erk2 cascadeGO:0070373210.051
regulation of neuron deathGO:19012141340.051
regulation of immunoglobulin secretionGO:0051023120.051
regulation of macrophage cytokine productionGO:001093580.050
multi multicellular organism processGO:00447061090.050
anatomical structure homeostasisGO:00602491450.050
regulation of wound healingGO:0061041400.050
positive regulation of t cell extravasationGO:200040920.050
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.049
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.049
regulation of immunoglobulin productionGO:0002637420.049
activation of mapk activityGO:0000187590.049
response to insulinGO:00328681000.049
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.049
erk1 and erk2 cascadeGO:0070371770.049
detection of lipopolysaccharideGO:003249710.049
interleukin 27 mediated signaling pathwayGO:007010610.049
cell cell recognitionGO:0009988440.049
carbohydrate derivative biosynthetic processGO:19011371830.048
dna recombinationGO:0006310920.048
purine ribonucleoside metabolic processGO:00461282410.048
glycerolipid metabolic processGO:00464861220.048
regulation of lymphocyte proliferationGO:00506701170.048
negative regulation of multi organism processGO:0043901680.048
nuclear importGO:0051170950.047
negative regulation of molecular functionGO:00440922580.047
acid secretionGO:0046717330.047
response to monosaccharideGO:0034284670.047
regulation of epithelial cell proliferationGO:00506781410.047
inflammatory cell apoptotic processGO:0006925110.047
organonitrogen compound biosynthetic processGO:19015661920.047
purine ribonucleotide metabolic processGO:00091502900.047
positive regulation of protein localization to nucleusGO:1900182300.047
lymphocyte proliferationGO:00466511640.046
regulation of growth of symbiont in hostGO:0044126190.046
peptidyl serine phosphorylationGO:0018105740.046
positive regulation of chemokine productionGO:0032722220.046
regulation of homeostatic processGO:00328441820.046
positive regulation by organism of defense response of other organism involved in symbiotic interactionGO:005251010.046
positive regulation of cytoplasmic transportGO:1903651400.046
response to hyperoxiaGO:005509320.046
regulation of interferon beta biosynthetic processGO:004535740.046
response to radiationGO:00093141650.045
regulation of peptidyl serine phosphorylationGO:0033135390.045
regulation of cellular catabolic processGO:00313292420.045
regulation of smad protein import into nucleusGO:006039030.045
regulation of map kinase activityGO:00434051200.045
negative regulation of reactive oxygen species biosynthetic processGO:190342700.045
protein maturationGO:00516041760.045
production of molecular mediator of immune responseGO:00024401030.045
small molecule catabolic processGO:0044282710.045
regulation of response to oxidative stressGO:1902882190.044
cell maturationGO:00484691270.044
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.044
regulation of angiogenesisGO:0045765810.044
female gamete generationGO:0007292740.044
cation transportGO:00068123990.044
tissue homeostasisGO:00018941150.044
protein localization to organelleGO:00333651850.044
modulation of growth of symbiont involved in interaction with hostGO:0044144190.044
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.043
cytokine secretion involved in immune responseGO:000237460.043
regulation of interleukin 13 secretionGO:200066520.043
interleukin 13 secretionGO:007261120.043
positive regulation of monocyte extravasationGO:200043910.043
regulation of hormone secretionGO:0046883880.043
alpha amino acid metabolic processGO:1901605590.043
cellular response to lipoteichoic acidGO:007122360.043
fat cell differentiationGO:00454441600.042
response to nitric oxideGO:007173140.042
t cell differentiationGO:00302171740.042
regulation of t cell activationGO:00508631700.042
nitric oxide mediated signal transductionGO:000726340.042
positive regulation of proteolysisGO:0045862850.042
ammonia assimilation cycleGO:001967620.042
regulation of mammary gland involutionGO:190351940.041
regulation of reactive oxygen species metabolic processGO:2000377400.041
regulation of tumor necrosis factor biosynthetic processGO:0042534100.041
regulation of interleukin 23 productionGO:003266720.041
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.041
regulation of transmembrane transportGO:00347621280.041
regulation of nucleocytoplasmic transportGO:0046822730.041
somatic diversification of immune receptorsGO:0002200530.041
response to metal ionGO:0010038470.041
regulation of interleukin 5 secretionGO:200066220.041
negative regulation of odontogenesis of dentin containing toothGO:004248910.040
myeloid leukocyte differentiationGO:00025731190.040
epithelium migrationGO:0090132630.040
lipid transportGO:0006869980.040
hemostasisGO:0007599780.040
response to interleukin 6GO:0070741100.040
interleukin 8 productionGO:003263740.040
response to light stimulusGO:00094161350.040
skin developmentGO:00435882200.039
purine nucleoside metabolic processGO:00422782410.039

Spp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinal diseaseDOID:567900.437
sensory system diseaseDOID:005015500.437
disease of anatomical entityDOID:700.437
eye and adnexa diseaseDOID:149200.437
nervous system diseaseDOID:86300.437
eye diseaseDOID:561400.437
retinal degenerationDOID:846600.247
disease of metabolismDOID:001466700.168
degeneration of macula and posterior poleDOID:200700.115
macular degenerationDOID:444800.115
age related macular degenerationDOID:1087100.115
inflammatory bowel diseaseDOID:005058900.081
gastrointestinal system diseaseDOID:7700.081
intestinal diseaseDOID:529500.081
carbohydrate metabolism diseaseDOID:005001300.062
acquired metabolic diseaseDOID:006015800.062
diabetes mellitusDOID:935100.044
type 2 diabetes mellitusDOID:935200.044
glucose metabolism diseaseDOID:419400.044
inherited metabolic disorderDOID:65500.043
central nervous system diseaseDOID:33100.043