Mus musculus

20 known processes

Thbs4

thrombospondin 4

(Aliases: TSP4)

Thbs4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308450.094
muscle system processGO:00030121410.088
actin cytoskeleton organizationGO:00300362200.073
muscle cell differentiationGO:00426922610.067
blood vessel morphogenesisGO:00485142850.061
Human Mouse
cation transportGO:00068123990.061
regulation of system processGO:00440572000.060
response to growth factorGO:00708481980.058
Mouse
oxidation reduction processGO:00551143420.058
small gtpase mediated signal transductionGO:0007264970.056
cellular amino acid metabolic processGO:00065201030.056
muscle tissue developmentGO:00605373080.055
cellular amine metabolic processGO:0044106440.054
transmembrane transportGO:00550854120.054
cellular ketone metabolic processGO:0042180840.053
nucleotide metabolic processGO:00091173320.052
anatomical structure homeostasisGO:00602491450.049
skeletal system developmentGO:00015013560.049
Mouse
inorganic ion transmembrane transportGO:00986602340.048
circulatory system processGO:00030131970.048
rho protein signal transductionGO:0007266320.048
ossificationGO:00015032160.048
Mouse
regulation of cellular ketone metabolic processGO:0010565660.048
negative regulation of cell developmentGO:00107211690.047
regulation of cellular amine metabolic processGO:0033238200.046
developmental maturationGO:00217001930.045
Mouse
cellular response to lipidGO:00713961450.045
ras protein signal transductionGO:0007265770.045
striated muscle cell developmentGO:00550021250.043
skeletal muscle organ developmentGO:00605381630.042
Fly
ribose phosphate metabolic processGO:00196932910.042
response to organonitrogen compoundGO:00102432460.042
cell adhesionGO:00071553290.039
Human Mouse Fly
cellular lipid metabolic processGO:00442553230.039
multicellular organismal signalingGO:0035637910.039
purine ribonucleotide metabolic processGO:00091502900.039
regulation of cellular amino acid metabolic processGO:000652150.037
organonitrogen compound catabolic processGO:19015652640.037
regulation of membrane potentialGO:00423911920.037
negative regulation of molecular functionGO:00440922580.036
regulation of muscle system processGO:0090257800.035
striated muscle tissue developmentGO:00147062930.035
nucleoside phosphate metabolic processGO:00067533380.035
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
regulation of nucleotide metabolic processGO:00061401690.034
protein modification by small protein conjugation or removalGO:00706472070.033
muscle cell developmentGO:00550011330.033
negative regulation of protein metabolic processGO:00512482820.032
membrane organizationGO:00610242450.032
inflammatory responseGO:00069542440.032
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.032
sensory organ morphogenesisGO:00905962420.031
cation transmembrane transportGO:00986552660.031
purine containing compound metabolic processGO:00725213110.030
skin developmentGO:00435882200.030
cellular response to transforming growth factor beta stimulusGO:0071560880.030
Mouse
cellular response to acid chemicalGO:0071229680.029
monocarboxylic acid metabolic processGO:00327871910.029
purine nucleotide metabolic processGO:00061633020.029
organic cyclic compound catabolic processGO:19013612950.029
cellular macromolecule catabolic processGO:00442652060.029
positive regulation of cellular amine metabolic processGO:003324050.029
muscle contractionGO:00069361010.028
organ growthGO:00352651170.028
Mouse
extracellular structure organizationGO:00430621480.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
nucleoside phosphate catabolic processGO:19012922220.028
ribonucleotide metabolic processGO:00092592910.028
peptidyl amino acid modificationGO:00181933360.027
Human
purine nucleoside triphosphate metabolic processGO:00091442260.027
protein maturationGO:00516041760.027
cellular response to growth factor stimulusGO:00713631970.027
Mouse
cellular metal ion homeostasisGO:00068751510.027
regulation of proteolysisGO:00301621640.027
negative regulation of cellular protein metabolic processGO:00322692470.027
regulation of ras protein signal transductionGO:00465781140.027
cardiac muscle tissue developmentGO:00487381300.027
inorganic cation transmembrane transportGO:00986622070.027
fertilizationGO:00095661270.026
protein processingGO:00164851630.026
glycosyl compound metabolic processGO:19016572460.026
negative regulation of cell proliferationGO:00082852960.026
Mouse
muscle adaptationGO:0043500390.026
response to acid chemicalGO:00011011110.026
regulation of organelle organizationGO:00330432890.026
renal system developmentGO:00720012250.026
cytoplasmic transportGO:00164822340.025
sensory perceptionGO:00076002450.025
purine containing compound catabolic processGO:00725232130.025
hematopoietic progenitor cell differentiationGO:00022441430.025
positive regulation of protein phosphorylationGO:00019342420.025
Human
organic hydroxy compound metabolic processGO:19016152030.025
protein modification by small protein conjugationGO:00324461870.025
regulation of ion transportGO:00432692150.025
regulation of neuron differentiationGO:00456642810.025
nucleoside metabolic processGO:00091162460.024
axonogenesisGO:00074092740.024
cellular chemical homeostasisGO:00550822150.024
potassium ion transmembrane transportGO:0071805430.024
limb developmentGO:00601731660.024
regulation of response to woundingGO:19030341890.024
heterocycle catabolic processGO:00467002800.024
nucleoside triphosphate metabolic processGO:00091412300.023
camera type eye developmentGO:00430102660.023
actin filament organizationGO:00070151130.023
organonitrogen compound biosynthetic processGO:19015661920.023
urogenital system developmentGO:00016552610.023
negative regulation of phosphorus metabolic processGO:00105631840.023
regulation of cellular response to growth factor stimulusGO:0090287820.022
Mouse
angiogenesisGO:00015252010.022
Human Mouse
ribonucleoside metabolic processGO:00091192450.022
regulation of cellular component biogenesisGO:00440871810.022
purine nucleoside metabolic processGO:00422782410.022
divalent inorganic cation transportGO:00725111780.022
cellular protein complex assemblyGO:00436231160.022
divalent metal ion transportGO:00708381720.022
cellular homeostasisGO:00197252400.022
macromolecule catabolic processGO:00090572810.022
regulation of cell adhesionGO:00301551540.022
Mouse
cell substrate adhesionGO:00315891300.022
Mouse
negative regulation of nervous system developmentGO:00519611560.022
reactive oxygen species metabolic processGO:0072593840.021
heart morphogenesisGO:00030071780.021
Mouse
connective tissue developmentGO:00614481790.021
Zebrafish Mouse
regulation of metal ion transportGO:00109591060.021
cellular component assembly involved in morphogenesisGO:00109271390.021
anion transportGO:00068201770.021
protein localization to organelleGO:00333651850.021
purine nucleoside catabolic processGO:00061522050.021
cellular response to nitric oxideGO:007173240.020
Mouse
response to inorganic substanceGO:0010035960.020
Mouse
regulation of anatomical structure sizeGO:00900661780.020
cognitionGO:00508901490.020
regulation of muscle adaptationGO:0043502310.020
potassium ion transportGO:0006813520.020
negative regulation of cellular amine metabolic processGO:003323910.020
negative regulation of phosphate metabolic processGO:00459361840.020
forebrain developmentGO:00309003020.020
ion transmembrane transportGO:00342203610.020
cell maturationGO:00484691270.020
negative regulation of cellular amino acid metabolic processGO:004576300.020
regulation of protein processingGO:0070613960.020
organophosphate catabolic processGO:00464342320.020
respiratory system developmentGO:00605411900.020
regulation of cellular catabolic processGO:00313292420.020
nucleotide catabolic processGO:00091662170.020
cellular nitrogen compound catabolic processGO:00442702800.019
apoptotic signaling pathwayGO:00971903060.019
mitotic cell cycleGO:00002781950.019
regulation of protein maturationGO:1903317960.019
microtubule based processGO:00070172360.019
nucleoside triphosphate catabolic processGO:00091432050.019
positive regulation of protein modification processGO:00314012990.019
Human
regulation of purine nucleotide metabolic processGO:19005421690.019
nucleoside catabolic processGO:00091642060.019
regulation of blood circulationGO:1903522930.019
regulation of hormone levelsGO:00108172110.019
embryonic organ morphogenesisGO:00485622760.019
protein ubiquitinationGO:00165671710.019
response to organic cyclic compoundGO:00140701980.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.019
Mouse
cellular response to organonitrogen compoundGO:00714171450.019
extracellular matrix organizationGO:00301981470.018
male gamete generationGO:00482322850.018
blood circulationGO:00080151950.018
carboxylic acid transportGO:00469421000.018
positive regulation of nervous system developmentGO:00519622210.018
lipid biosynthetic processGO:00086101790.018
tissue homeostasisGO:00018941150.018
proteolysis involved in cellular protein catabolic processGO:00516031470.018
skeletal system morphogenesisGO:00487052030.018
Mouse
cellular response to external stimulusGO:0071496880.018
cellular response to hormone stimulusGO:00328701500.018
intracellular protein transportGO:00068862040.018
negative regulation of protein processingGO:0010955790.018
response to light stimulusGO:00094161350.018
telencephalon developmentGO:00215371860.018
regulation of cytokine productionGO:00018172660.018
limb morphogenesisGO:00351081490.018
action potentialGO:0001508780.018
regulation of ion transmembrane transportGO:00347651190.018
regulation of apoptotic signaling pathwayGO:20012331970.018
bone developmentGO:00603481200.018
Mouse
transmission of nerve impulseGO:0019226760.018
negative regulation of cellular component organizationGO:00511291940.018
spermatogenesisGO:00072832840.018
cation homeostasisGO:00550802120.018
calcium ion transmembrane transportGO:0070588850.017
regulation of rho protein signal transductionGO:0035023710.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
homeostasis of number of cellsGO:00488722100.017
modification dependent protein catabolic processGO:00199411330.017
carbohydrate metabolic processGO:00059752300.017
aromatic compound catabolic processGO:00194392860.017
organelle assemblyGO:00709251770.017
regulation of hydrolase activityGO:00513362460.017
organic anion transportGO:00157111370.017
negative regulation of phosphorylationGO:00423261660.017
mapk cascadeGO:00001652810.017
immune effector processGO:00022523210.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
regulation of body fluid levelsGO:00508781620.017
metal ion homeostasisGO:00550651890.017
actin mediated cell contractionGO:0070252150.017
cellular calcium ion homeostasisGO:00068741190.017
cellular protein catabolic processGO:00442571550.017
single fertilizationGO:0007338820.017
developmental growth involved in morphogenesisGO:00605601380.016
Mouse
nitrogen compound transportGO:00717052710.016
glycoprotein metabolic processGO:00091001160.016
positive regulation of cell developmentGO:00107202370.016
organophosphate biosynthetic processGO:00904071220.016
myotube differentiationGO:00149021050.016
glycosyl compound catabolic processGO:19016582060.016
carbohydrate derivative catabolic processGO:19011362310.016
regulation of reactive oxygen species biosynthetic processGO:190342620.016
regulation of cell migrationGO:00303342190.016
Human Mouse
reactive oxygen species biosynthetic processGO:190340980.016
purine ribonucleoside metabolic processGO:00461282410.016
digestive system developmentGO:00551232000.016
cellular response to inorganic substanceGO:0071241370.015
Mouse
rhythmic processGO:00485111740.015
protein catabolic processGO:00301632210.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
sensory perception of light stimulusGO:0050953540.015
negative regulation of hydrolase activityGO:0051346710.015
detection of stimulusGO:0051606840.015
striated muscle myosin thick filament assemblyGO:007168810.015
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.015
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.015
epithelial cell proliferationGO:00506731740.015
Human Mouse
negative regulation of proteolysisGO:0045861740.015
organelle fissionGO:00482851700.015
ribonucleotide catabolic processGO:00092612080.015
cell fate commitmentGO:00451652100.015
hormone metabolic processGO:0042445860.015
actin filament polymerizationGO:0030041440.015
cellular ion homeostasisGO:00068731650.015
ribonucleoside catabolic processGO:00424542060.015
proteasomal protein catabolic processGO:0010498980.015
regionalizationGO:00030023370.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
Mouse
regulation of epithelial cell proliferationGO:00506781410.015
Human Mouse
bmp signaling pathwayGO:0030509930.015
fatty acid metabolic processGO:00066311210.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
cellular potassium ion transportGO:0071804430.014
regulation of transmembrane transportGO:00347621280.014
mitochondrion organizationGO:00070051340.014
learning or memoryGO:00076111480.014
endocytosisGO:00068971680.014
synaptic transmissionGO:00072683290.014
appendage developmentGO:00487361660.014
defecationGO:003042110.014
positive regulation of neuron differentiationGO:00456661410.014
regulation of protein kinase activityGO:00458592320.014
sequestering of calcium ionGO:0051208180.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
striated muscle contractionGO:0006941450.014
regulation of defense responseGO:00313472330.014
lung developmentGO:00303241640.014
adult behaviorGO:00305341350.014
regulation of secretion by cellGO:19035302490.014
sensory perception of mechanical stimulusGO:00509541070.014
regulation of secretionGO:00510462740.014
reactive nitrogen species metabolic processGO:200105700.014
negative regulation of protein modification processGO:00314001630.014
regulation of heart contractionGO:0008016770.014
oocyte constructionGO:000730820.014
regulation of cell cycleGO:00517262810.014
regulation of kinase activityGO:00435492490.014
regulation of vesicle mediated transportGO:00606271390.014
divalent inorganic cation homeostasisGO:00725071380.014
embryonic epithelial tube formationGO:00018381300.014
retina development in camera type eyeGO:00600411190.014
regulation of neuron projection developmentGO:00109751690.014
cytokine productionGO:00018163190.014
mesenchyme developmentGO:00604851520.014
Mouse
response to nitric oxideGO:007173140.014
Mouse
response to extracellular stimulusGO:00099911270.014
cardiocyte differentiationGO:0035051870.013
epithelial cell morphogenesisGO:0003382410.013
actin polymerization or depolymerizationGO:0008154540.013
cellular modified amino acid metabolic processGO:0006575630.013
cardiac chamber morphogenesisGO:0003206930.013
gonad developmentGO:00084061410.013
leukocyte differentiationGO:00025213420.013
multicellular organismal response to stressGO:0033555620.013
cell type specific apoptotic processGO:00972852680.013
wound healingGO:00420601570.013
negative regulation of immune system processGO:00026832090.013
g protein coupled receptor signaling pathwayGO:00071862430.013
protein targetingGO:00066051430.013
protein localization to membraneGO:00726571080.013
small molecule biosynthetic processGO:00442831320.013
regulation of cytoskeleton organizationGO:00514931220.013
mitochondrion distributionGO:004831140.013
carbohydrate derivative biosynthetic processGO:19011371830.013
trabecula formationGO:0060343240.013
Mouse
positive regulation of cell adhesionGO:0045785800.013
Mouse
learningGO:0007612980.013
heart contractionGO:0060047930.013
epithelial cell developmentGO:00020641590.013
chemotaxisGO:00069352470.013
Human Mouse
purine ribonucleoside catabolic processGO:00461302050.013
response to starvationGO:0042594650.013
wnt signaling pathwayGO:00160551880.013
response to oxygen levelsGO:0070482620.013
response to molecule of bacterial originGO:00022371430.012
regulation of cell activationGO:00508652890.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
regulation of inflammatory responseGO:00507271470.012
calcium ion homeostasisGO:00550741270.012
neuron neuron synaptic transmissionGO:0007270690.012
multicellular organismal homeostasisGO:00488711640.012
protein polymerizationGO:0051258570.012
kidney developmentGO:00018222130.012
microtubule cytoskeleton organizationGO:00002261570.012
negative regulation of intracellular signal transductionGO:19025321670.012
mitotic cell cycle processGO:19030471590.012
posttranscriptional regulation of gene expressionGO:00106081550.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
pallium developmentGO:00215431200.012
physiological cardiac muscle hypertrophyGO:000330130.012
t cell activationGO:00421102890.012
interleukin 8 productionGO:003263740.012
regulation of ossificationGO:00302781120.012
carbohydrate homeostasisGO:00335001280.012
engulfment of apoptotic cellGO:004365230.012
cellular response to oxidative stressGO:0034599760.012
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
placenta developmentGO:00018901400.012
regulation of mitotic cell cycleGO:00073461260.012
regulation of peptidase activityGO:0052547960.012
sulfur compound metabolic processGO:00067901000.012
regulation of actin filament based processGO:0032970990.012
skeletal myofibril assemblyGO:001486640.012
nuclear divisionGO:00002801580.012
regulation of interleukin 8 productionGO:003267730.012
regulation of ras gtpase activityGO:0032318880.012
regulation of cell motilityGO:20001452360.012
Human Mouse
cellular response to steroid hormone stimulusGO:0071383330.012
regulation of neuron deathGO:19012141340.012
calcium ion transportGO:00068161590.012
regulation of intracellular transportGO:00323861590.012
negative regulation of protein maturationGO:1903318790.012
regulation of protein transportGO:00512231630.012
epidermis developmentGO:00085441870.012
cardiac chamber developmentGO:00032051080.012
regulation of purine nucleotide catabolic processGO:00331211220.012
response to transforming growth factor betaGO:0071559880.012
Mouse
positive regulation of secretionGO:00510471300.011
myeloid cell differentiationGO:00300992330.011
heart processGO:0003015940.011
ubiquitin dependent protein catabolic processGO:00065111290.011
t cell differentiationGO:00302171740.011
ear developmentGO:00435832000.011
lymphocyte proliferationGO:00466511640.011
b cell activationGO:00421131610.011
purine ribonucleotide catabolic processGO:00091542080.011
regulation of endocytosisGO:0030100690.011
actin filament based movementGO:0030048230.011
organelle localizationGO:00516401790.011
negative regulation of cytokine productionGO:0001818840.011
cerebral cortex developmentGO:0021987860.011
respiratory tube developmentGO:00303231670.011
cardiac muscle cell differentiationGO:0055007690.011
morphogenesis of embryonic epitheliumGO:00163311590.011
maintenance of locationGO:0051235890.011
appendage morphogenesisGO:00351071490.011
cellular response to biotic stimulusGO:0071216920.011
purine nucleotide catabolic processGO:00061952110.011
cardiac cell developmentGO:0055006410.011
peptidyl serine modificationGO:0018209830.011
cellular response to cytokine stimulusGO:00713451890.011
neuromuscular processGO:0050905990.011
negative regulation of epithelial cell proliferationGO:0050680640.011
Mouse
regulation of cell projection organizationGO:00313442060.011
positive regulation of transferase activityGO:00513471670.011
long chain fatty acid importGO:004453920.011
neuron deathGO:00709971540.011
regulation of neuron apoptotic processGO:00435231220.010
regulation of leukocyte differentiationGO:19021051590.010
modification dependent macromolecule catabolic processGO:00436321330.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.010
cellular response to extracellular stimulusGO:0031668810.010
compound eye developmentGO:004874910.010
positive regulation of mapk cascadeGO:00434101700.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
organic acid transportGO:00158491010.010
sequestering of metal ionGO:0051238190.010
regulation of cell growthGO:0001558910.010
regulation of vasculature developmentGO:1901342880.010
Human Mouse
positive regulation of growthGO:00459271040.010
lymphocyte differentiationGO:00300982420.010
positive regulation of vasoconstrictionGO:004590740.010
amino acid transportGO:0006865610.010
primary neural tube formationGO:0014020950.010
organic hydroxy compound biosynthetic processGO:1901617770.010
visceral serous pericardium developmentGO:006103220.010
endochondral bone morphogenesisGO:0060350500.010
Mouse
cardiac muscle contractionGO:0060048320.010

Thbs4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.137
disease of anatomical entityDOID:700.137
connective tissue diseaseDOID:6500.069
muscular diseaseDOID:008000000.061
muscle tissue diseaseDOID:6600.061
myopathyDOID:42300.043
nervous system diseaseDOID:86300.028
sensory system diseaseDOID:005015500.017
heart diseaseDOID:11400.017
cardiovascular system diseaseDOID:128700.017
cardiomyopathyDOID:005070000.017
bone diseaseDOID:008000100.016
bone development diseaseDOID:008000600.016
osteochondrodysplasiaDOID:225600.014
eye and adnexa diseaseDOID:149200.011
disease of metabolismDOID:001466700.011