Mus musculus

0 known processes

Tifab

TRAF-interacting protein with forkhead-associated domain, family member B

(Aliases: MGC37193,MGC32345)

Tifab biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
serotonin secretion by mast cellGO:000255210.322
regulation of mast cell activationGO:0033003210.266
immune effector processGO:00022523210.200
regulation of innate immune responseGO:0045088910.127
regulation of toll like receptor 9 signaling pathwayGO:003416330.122
cellular response to peptidoglycanGO:007122440.116
negative regulation of immune system processGO:00026832090.095
myeloid cell differentiationGO:00300992330.091
toll like receptor 9 signaling pathwayGO:003416260.089
regulation of cell activationGO:00508652890.088
purinergic nucleotide receptor signaling pathwayGO:003559030.087
regulation of defense responseGO:00313472330.083
defense response to other organismGO:00985421970.083
regulation of secretionGO:00510462740.073
leukocyte differentiationGO:00025213420.071
defense response to bacteriumGO:00427421190.070
myeloid leukocyte differentiationGO:00025731190.070
myeloid leukocyte activationGO:0002274830.069
negative regulation of mast cell degranulationGO:004330540.069
purinergic receptor signaling pathwayGO:003558770.069
regulation of inflammatory responseGO:00507271470.068
positive regulation of toll like receptor 9 signaling pathwayGO:003416520.068
regulation of secretion by cellGO:19035302490.058
immunoglobulin transcytosis in epithelial cellsGO:000241420.058
cell adhesionGO:00071553290.055
cytokine productionGO:00018163190.054
regulation of cellular ketone metabolic processGO:0010565660.053
g protein coupled receptor signaling pathwayGO:00071862430.052
mast cell degranulationGO:0043303190.052
amine metabolic processGO:0009308450.051
chemotaxisGO:00069352470.051
leukocyte activation involved in immune responseGO:00023661260.051
activation of innate immune responseGO:0002218560.050
leukocyte mediated immunityGO:00024431740.050
cellular ketone metabolic processGO:0042180840.049
immune response regulating signaling pathwayGO:00027641250.049
regulation of leukocyte mediated immunityGO:00027031040.049
positive regulation of immune effector processGO:00026991070.048
toll like receptor 7 signaling pathwayGO:003415440.047
regulation of protein localizationGO:00328802310.047
negative regulation of serotonin secretionGO:001406320.045
ribonucleoside triphosphate catabolic processGO:00092031990.045
cation transportGO:00068123990.045
cellular lipid metabolic processGO:00442553230.045
detection of molecule of bacterial originGO:003249020.045
mast cell activation involved in immune responseGO:0002279200.043
positive regulation of protein modification processGO:00314012990.043
purine containing compound catabolic processGO:00725232130.043
exocytosisGO:00068871210.041
positive regulation of defense responseGO:00313491240.041
t cell activationGO:00421102890.040
nitrogen compound transportGO:00717052710.040
mapk cascadeGO:00001652810.039
lysosome localizationGO:0032418200.039
regulation of serotonin secretionGO:001406230.039
cytokine secretionGO:0050663720.038
ribose phosphate metabolic processGO:00196932910.038
regulation of intracellular transportGO:00323861590.038
regulation of organelle organizationGO:00330432890.038
negative regulation of immune effector processGO:0002698550.038
regulation of lymphocyte activationGO:00512492400.038
monocarboxylic acid metabolic processGO:00327871910.037
cell activation involved in immune responseGO:00022631260.036
innate immune response activating signal transductionGO:0002758500.036
purine nucleoside metabolic processGO:00422782410.036
purine containing compound metabolic processGO:00725213110.035
regulation of cytokine productionGO:00018172660.035
regulation of exocytosisGO:0017157610.035
organonitrogen compound biosynthetic processGO:19015661920.035
cellular chemical homeostasisGO:00550822150.035
cellular nitrogen compound catabolic processGO:00442702800.035
cellular amino acid metabolic processGO:00065201030.035
organic cyclic compound catabolic processGO:19013612950.034
mast cell mediated immunityGO:0002448200.034
mast cell activationGO:0045576270.034
immune response activating signal transductionGO:00027571160.034
negative regulation of cell activationGO:00508661110.034
regulation of vesicle mediated transportGO:00606271390.034
purine ribonucleoside triphosphate metabolic processGO:00092052200.033
membrane organizationGO:00610242450.033
positive regulation of protein transportGO:0051222930.033
myeloid leukocyte mediated immunityGO:0002444420.033
positive regulation of innate immune responseGO:0045089800.032
carbohydrate metabolic processGO:00059752300.032
positive regulation of cell deathGO:00109422240.032
nucleobase containing small molecule metabolic processGO:00550863520.032
nucleoside metabolic processGO:00091162460.032
cellular homeostasisGO:00197252400.032
purine ribonucleoside metabolic processGO:00461282410.031
aromatic compound catabolic processGO:00194392860.031
heterocycle catabolic processGO:00467002800.030
detection of peptidoglycanGO:003249910.030
purine ribonucleotide catabolic processGO:00091542080.030
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558910.030
organelle localizationGO:00516401790.030
maintenance of locationGO:0051235890.030
transmembrane transportGO:00550854120.030
adaptive immune responseGO:00022501550.030
hematopoietic progenitor cell differentiationGO:00022441430.030
negative regulation of lymphocyte activationGO:0051250910.030
positive regulation of secretion by cellGO:19035321140.030
cellular carbohydrate metabolic processGO:00442621190.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
protein secretionGO:00093061110.030
b cell activationGO:00421131610.030
organelle assemblyGO:00709251770.029
lymphocyte mediated immunityGO:00024491390.029
protein ubiquitinationGO:00165671710.029
response to organonitrogen compoundGO:00102432460.029
serotonin secretion involved in inflammatory responseGO:000244240.029
toll like receptor signaling pathwayGO:0002224380.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
sequestering of calcium ionGO:0051208180.029
regulation of cellular amino acid metabolic processGO:000652150.029
regulation of cell motilityGO:20001452360.029
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.029
cellular response to organonitrogen compoundGO:00714171450.029
inflammatory responseGO:00069542440.029
oxidation reduction processGO:00551143420.028
histamine transportGO:005160820.028
cellular amine metabolic processGO:0044106440.028
homeostasis of number of cellsGO:00488722100.028
response to lipopolysaccharideGO:00324961280.028
reactive oxygen species metabolic processGO:0072593840.027
camera type eye developmentGO:00430102660.027
regulation of mapk cascadeGO:00434082480.027
regulation of kinase activityGO:00435492490.027
pattern recognition receptor signaling pathwayGO:0002221470.027
ion transmembrane transportGO:00342203610.027
regulation of protein secretionGO:0050708820.027
peptidyl amino acid modificationGO:00181933360.027
ribonucleoside metabolic processGO:00091192450.027
nucleoside catabolic processGO:00091642060.027
myeloid cell activation involved in immune responseGO:0002275340.027
cell type specific apoptotic processGO:00972852680.027
protein modification by small protein conjugation or removalGO:00706472070.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
sequestering of metal ionGO:0051238190.026
positive regulation of cytokine productionGO:00018191740.026
response to molecule of bacterial originGO:00022371430.026
purine nucleotide metabolic processGO:00061633020.026
positive regulation of cellular amine metabolic processGO:003324050.026
positive regulation of protein secretionGO:0050714520.026
tissue homeostasisGO:00018941150.026
ras protein signal transductionGO:0007265770.026
regulation of membrane potentialGO:00423911920.025
positive regulation of cytokine secretionGO:0050715410.025
regulation of interleukin 6 productionGO:0032675550.025
calcium ion transportGO:00068161590.025
organic hydroxy compound transportGO:0015850930.025
cellular response to external stimulusGO:0071496880.025
negative regulation of mast cell activationGO:003300460.025
purine ribonucleoside catabolic processGO:00461302050.024
negative regulation of leukocyte mediated immunityGO:0002704290.024
detection of lipoteichoic acidGO:007039210.024
ribonucleotide metabolic processGO:00092592910.024
sensory perceptionGO:00076002450.024
negative regulation of cellular amino acid metabolic processGO:004576300.024
response to growth factorGO:00708481980.024
regulation of establishment of protein localizationGO:00702011810.024
regulation of cellular amine metabolic processGO:0033238200.024
production of molecular mediator of immune responseGO:00024401030.024
negative regulation of phagocytosisGO:005076540.024
divalent metal ion transportGO:00708381720.024
regulation of nucleotide metabolic processGO:00061401690.023
nucleoside phosphate catabolic processGO:19012922220.023
regulation of hormone levelsGO:00108172110.023
cation transmembrane transportGO:00986552660.023
regulated secretory pathwayGO:0045055320.023
regulation of ion transportGO:00432692150.023
regulation of cellular catabolic processGO:00313292420.023
negative regulation of cellular amine metabolic processGO:003323910.023
regulation of protein transportGO:00512231630.023
purine nucleoside triphosphate catabolic processGO:00091462030.023
endocytosisGO:00068971680.023
carbohydrate derivative catabolic processGO:19011362310.023
germ cell developmentGO:00072811850.023
cellular response to lipopolysaccharideGO:0071222770.023
inorganic ion transmembrane transportGO:00986602340.022
positive regulation of kinase activityGO:00336741550.022
ribonucleotide catabolic processGO:00092612080.022
nucleotide metabolic processGO:00091173320.022
leukocyte proliferationGO:00706611720.022
activation of immune responseGO:00022531380.022
cellular response to lipidGO:00713961450.022
negative regulation of mast cell activation involved in immune responseGO:003300750.022
purine ribonucleotide metabolic processGO:00091502900.022
developmental maturationGO:00217001930.022
protein modification by small protein conjugationGO:00324461870.022
nucleotide catabolic processGO:00091662170.022
regulation of leukocyte differentiationGO:19021051590.022
nucleoside phosphate metabolic processGO:00067533380.021
glycosyl compound metabolic processGO:19016572460.021
muscle cell differentiationGO:00426922610.021
purine nucleoside triphosphate metabolic processGO:00091442260.021
organophosphate biosynthetic processGO:00904071220.021
small gtpase mediated signal transductionGO:0007264970.021
carbohydrate homeostasisGO:00335001280.020
interleukin 18 productionGO:003262140.020
reactive oxygen species biosynthetic processGO:190340980.020
negative regulation of cell proliferationGO:00082852960.020
immune response activating cell surface receptor signaling pathwayGO:0002429720.020
multicellular organismal homeostasisGO:00488711640.020
interleukin 6 productionGO:0032635580.020
production of molecular mediator involved in inflammatory responseGO:0002532210.020
purine nucleotide catabolic processGO:00061952110.020
phagocytosisGO:0006909660.020
negative regulation of protein metabolic processGO:00512482820.020
learning or memoryGO:00076111480.020
phosphatidylinositol 3 kinase signalingGO:0014065360.020
dna metabolic processGO:00062593030.019
regulation of cell migrationGO:00303342190.019
divalent inorganic cation transportGO:00725111780.019
positive regulation of interleukin 18 productionGO:003274120.019
nucleoside triphosphate catabolic processGO:00091432050.019
negative regulation of defense responseGO:0031348770.019
chromatin organizationGO:00063252060.019
intestinal epithelial structure maintenanceGO:006072940.019
regulation of actin cytoskeleton organizationGO:0032956840.019
regulation of regulated secretory pathwayGO:1903305200.019
glycosyl compound catabolic processGO:19016582060.018
axonogenesisGO:00074092740.018
positive regulation of protein kinase activityGO:00458601440.018
cellular response to biotic stimulusGO:0071216920.018
action potentialGO:0001508780.018
organonitrogen compound catabolic processGO:19015652640.018
regulation of anatomical structure sizeGO:00900661780.018
inorganic cation transmembrane transportGO:00986622070.018
positive regulation of secretionGO:00510471300.018
lipid biosynthetic processGO:00086101790.018
glucose homeostasisGO:00425931280.018
organophosphate catabolic processGO:00464342320.018
regulation of system processGO:00440572000.018
interferon beta biosynthetic processGO:004535040.018
gtp catabolic processGO:00061841430.018
lymphocyte differentiationGO:00300982420.018
regulation of protein kinase activityGO:00458592320.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
anatomical structure homeostasisGO:00602491450.018
regulation of reactive oxygen species biosynthetic processGO:190342620.018
serotonin production involved in inflammatory responseGO:000235140.018
skeletal system developmentGO:00015013560.017
regulation of antimicrobial peptide biosynthetic processGO:000280510.017
glycerophospholipid metabolic processGO:0006650710.017
regulation of cellular response to stressGO:00801351590.017
cell fate commitmentGO:00451652100.017
positive regulation of cellular catabolic processGO:00313311480.017
positive regulation of interferon alpha productionGO:003272740.017
spermatogenesisGO:00072832840.017
antimicrobial peptide biosynthetic processGO:000277720.017
hemostasisGO:0007599780.017
male gamete generationGO:00482322850.017
fatty acid derivative metabolic processGO:1901568330.017
carbohydrate derivative biosynthetic processGO:19011371830.017
positive regulation of transferase activityGO:00513471670.017
regulation of myeloid cell differentiationGO:0045637960.017
regulation of transferase activityGO:00513382630.017
regulation of b cell activationGO:0050864810.017
rho protein signal transductionGO:0007266320.017
glycerolipid metabolic processGO:00464861220.017
regulation of hydrolase activityGO:00513362460.017
response to extracellular stimulusGO:00099911270.017
innate immune responseGO:00450871570.017
positive regulation of apoptotic processGO:00430652170.017
mitotic cell cycleGO:00002781950.016
skin developmentGO:00435882200.016
posttranscriptional regulation of gene expressionGO:00106081550.016
negative regulation of cellular protein metabolic processGO:00322692470.016
regulation of cytokine secretionGO:0050707610.016
hormone secretionGO:00468791280.016
erk1 and erk2 cascadeGO:0070371770.016
positive regulation of mapk cascadeGO:00434101700.016
negative regulation of intracellular signal transductionGO:19025321670.016
negative regulation of cellular component organizationGO:00511291940.016
intracellular protein transportGO:00068862040.016
regulation of neuron differentiationGO:00456642810.016
cellular metal ion homeostasisGO:00068751510.016
renal system developmentGO:00720012250.016
stem cell differentiationGO:00488632680.016
negative regulation of secretion by cellGO:1903531540.016
regulation of response to woundingGO:19030341890.016
negative regulation of secretionGO:0051048610.016
blood circulationGO:00080151950.016
osteoclast differentiationGO:0030316620.016
lymphocyte homeostasisGO:0002260640.016
cellular response to extracellular stimulusGO:0031668810.016
urogenital system developmentGO:00016552610.015
lymphocyte activation involved in immune responseGO:0002285930.015
microtubule based processGO:00070172360.015
reactive nitrogen species metabolic processGO:200105700.015
purine nucleoside catabolic processGO:00061522050.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
epithelial tube morphogenesisGO:00605623030.015
neutrophil mediated immunityGO:0002446190.015
synapse organizationGO:00508081250.015
macromolecule methylationGO:00434141200.015
microtubule cytoskeleton organizationGO:00002261570.015
regulation of mast cell degranulationGO:0043304160.015
cognitionGO:00508901490.015
leukocyte degranulationGO:0043299270.015
protein kinase b signalingGO:0043491740.015
organic hydroxy compound metabolic processGO:19016152030.015
embryonic organ morphogenesisGO:00485622760.015
glycoprotein metabolic processGO:00091001160.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
regulation of ion homeostasisGO:2000021640.015
regulation of myeloid leukocyte differentiationGO:0002761580.015
immune response regulating cell surface receptor signaling pathwayGO:0002768800.014
phospholipid metabolic processGO:0006644870.014
methylationGO:00322591340.014
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.014
ossificationGO:00015032160.014
glycosylationGO:0070085620.014
positive regulation of programmed cell deathGO:00430682180.014
regulation of body fluid levelsGO:00508781620.014
b cell mediated immunityGO:0019724710.014
regulation of purine nucleotide catabolic processGO:00331211220.014
forebrain developmentGO:00309003020.014
ribonucleoside catabolic processGO:00424542060.014
extracellular matrix organizationGO:00301981470.014
cardiac muscle tissue developmentGO:00487381300.014
leukocyte migrationGO:00509001240.014
regulation of nucleotide catabolic processGO:00308111220.014
epidermis developmentGO:00085441870.014
regulation of purine nucleotide metabolic processGO:19005421690.014
guanosine containing compound metabolic processGO:19010681440.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
multicellular organismal signalingGO:0035637910.014
phosphatidylinositol mediated signalingGO:0048015410.014
cellular response to growth factor stimulusGO:00713631970.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
positive regulation of hydrolase activityGO:00513451480.014
neural precursor cell proliferationGO:00613511210.013
positive regulation of cell migrationGO:00303351090.013
fatty acid metabolic processGO:00066311210.013
transmission of nerve impulseGO:0019226760.013
wound healingGO:00420601570.013
nucleoside triphosphate metabolic processGO:00091412300.013
regulation of interferon beta biosynthetic processGO:004535740.013
ear developmentGO:00435832000.013
immunoglobulin productionGO:0002377730.013
cation homeostasisGO:00550802120.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.013
connective tissue developmentGO:00614481790.013
regulation of homeostatic processGO:00328441820.013
kidney developmentGO:00018222130.013
metal ion homeostasisGO:00550651890.013
circulatory system processGO:00030131970.013
regulation of antimicrobial peptide productionGO:000278410.013
macromolecule catabolic processGO:00090572810.013
multicellular organism growthGO:00352641610.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
lymphocyte proliferationGO:00466511640.013
b cell proliferationGO:0042100530.013
regionalizationGO:00030023370.012
cellular calcium ion homeostasisGO:00068741190.012
regulation of cell cycleGO:00517262810.012
tube formationGO:00351481400.012
regulation of actin filament based processGO:0032970990.012
antimicrobial peptide productionGO:000277520.012
neuron projection guidanceGO:00974851410.012
regulation of blood pressureGO:0008217930.012
regulation of lymphocyte proliferationGO:00506701170.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
positive regulation of gtp catabolic processGO:0033126850.012
negative regulation of homeostatic processGO:0032845710.012
retrograde transport endosome to golgiGO:004214720.012
cell chemotaxisGO:0060326810.012
cellular response to molecule of bacterial originGO:0071219830.012
spermatid developmentGO:00072861080.012
positive regulation of cell activationGO:00508671580.012
cell surface pattern recognition receptor signaling pathwayGO:000275220.012
positive regulation of intracellular transportGO:0032388700.012
digestive tract developmentGO:00485651900.012
cell killingGO:0001906670.012
positive regulation of organelle organizationGO:00106381280.012
response to organic cyclic compoundGO:00140701980.012
cell maturationGO:00484691270.012
regulation of phagocytosisGO:0050764330.012
respiratory system developmentGO:00605411900.012
regulation of tube sizeGO:0035150570.012
epithelial cell proliferationGO:00506731740.012
negative regulation of synapse assemblyGO:005196430.012
calcium ion homeostasisGO:00550741270.012
negative regulation of protein modification processGO:00314001630.012
fat cell differentiationGO:00454441600.012
positive regulation of regulated secretory pathwayGO:1903307100.012
regulation of toll like receptor signaling pathwayGO:0034121200.012
generation of precursor metabolites and energyGO:00060911030.012
neuronal action potentialGO:0019228540.012
cellular response to cytokine stimulusGO:00713451890.011
regulation of nucleoside metabolic processGO:00091181300.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
nucleoside monophosphate metabolic processGO:0009123850.011
positive regulation of interferon alpha biosynthetic processGO:004535610.011
cytoplasmic transportGO:00164822340.011
regulation of lipid metabolic processGO:00192161180.011
response to acid chemicalGO:00011011110.011
cellular response to carbohydrate stimulusGO:0071322500.011
response to radiationGO:00093141650.011
extracellular structure organizationGO:00430621480.011
sensory organ morphogenesisGO:00905962420.011
negative regulation of leukocyte differentiationGO:1902106510.011
regulation of erk1 and erk2 cascadeGO:0070372710.011
positive regulation of phospholipase activityGO:001051830.011
negative regulation of organelle organizationGO:0010639900.011
detection of lipopolysaccharideGO:003249710.011
cytosolic calcium ion transportGO:0060401480.011
cellular protein complex assemblyGO:00436231160.011
erythrocyte differentiationGO:0030218880.011
regulation of ossificationGO:00302781120.011
positive regulation of neuron differentiationGO:00456661410.011
regulation of cytoskeleton organizationGO:00514931220.011
morphogenesis of embryonic epitheliumGO:00163311590.011
intracellular distribution of mitochondriaGO:004831210.011
blood vessel morphogenesisGO:00485142850.011
guanosine containing compound catabolic processGO:19010691440.011
cellular response to hexose stimulusGO:0071331470.011
positive regulation of ion transportGO:0043270650.011
regulation of leukocyte degranulationGO:0043300200.011
regulation of cellular component biogenesisGO:00440871810.011
gliogenesisGO:00420631410.011
inositol lipid mediated signalingGO:0048017410.011
muscle contractionGO:00069361010.011
regulation of chemokine productionGO:0032642300.011
calcium mediated signalingGO:0019722460.011
regulation of leukocyte proliferationGO:00706631210.011
positive regulation of cell developmentGO:00107202370.011
negative regulation of nik nf kappab signalingGO:190122320.011
histone modificationGO:00165701590.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
positive regulation of interleukin 8 productionGO:003275720.010
small molecule biosynthetic processGO:00442831320.010
chemokine productionGO:0032602340.010
regulation of calcium mediated signalingGO:0050848190.010
b cell homeostasisGO:0001782340.010
morphogenesis of a branching structureGO:00017632030.010
cellular response to hormone stimulusGO:00328701500.010
positive regulation of leukocyte mediated immunityGO:0002705700.010
regulation of mast cell activation involved in immune responseGO:0033006170.010
canonical wnt signaling pathwayGO:00600701300.010
body fluid secretionGO:0007589530.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
glucose metabolic processGO:0006006920.010
cellular macromolecule catabolic processGO:00442652060.010
compound eye developmentGO:004874910.010
negative regulation of cell developmentGO:00107211690.010
potassium ion transportGO:0006813520.010
angiogenesisGO:00015252010.010
response to peptidoglycanGO:003249490.010
regulation of metal ion transportGO:00109591060.010
wnt signaling pathwayGO:00160551880.010
gtp metabolic processGO:00460391440.010
muscle system processGO:00030121410.010
response to oxidative stressGO:00069791230.010
positive regulation of exocytosisGO:0045921200.010

Tifab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.019
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.010