Mus musculus

7 known processes

Casp6

caspase 6

(Aliases: Mch2,mCASP-6)

Casp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of immune system processGO:00026832090.092
Mouse
regulation of defense responseGO:00313472330.081
Mouse
cytokine productionGO:00018163190.078
Mouse
regulation of cytokine productionGO:00018172660.072
Mouse
protein maturationGO:00516041760.068
Mouse Fly
protein processingGO:00164851630.068
Mouse Fly
immune effector processGO:00022523210.057
response to lipopolysaccharideGO:00324961280.056
Mouse
oxidation reduction processGO:00551143420.056
cellular amino acid metabolic processGO:00065201030.053
negative regulation of protein metabolic processGO:00512482820.051
Mouse
regulation of cell activationGO:00508652890.050
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.050
Mouse
negative regulation of cell proliferationGO:00082852960.048
Mouse
regulation of cellular ketone metabolic processGO:0010565660.047
amine metabolic processGO:0009308450.046
response to molecule of bacterial originGO:00022371430.045
Mouse
regulation of hydrolase activityGO:00513362460.044
Mouse Fly
innate immune responseGO:00450871570.042
leukocyte differentiationGO:00025213420.041
Mouse
organic cyclic compound catabolic processGO:19013612950.041
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.041
Mouse
response to organic cyclic compoundGO:00140701980.041
Mouse
negative regulation of phosphate metabolic processGO:00459361840.040
Mouse
male gamete generationGO:00482322850.040
Fly
cellular lipid metabolic processGO:00442553230.039
apoptotic signaling pathwayGO:00971903060.039
Mouse Fly
dna metabolic processGO:00062593030.038
Mouse
cellular ketone metabolic processGO:0042180840.038
regulation of cellular amino acid metabolic processGO:000652150.037
negative regulation of molecular functionGO:00440922580.036
Mouse
regulation of transferase activityGO:00513382630.036
Mouse
cellular response to lipidGO:00713961450.036
Mouse
regulation of lymphocyte activationGO:00512492400.036
Mouse
positive regulation of protein modification processGO:00314012990.036
heterocycle catabolic processGO:00467002800.036
Mouse
cellular amine metabolic processGO:0044106440.035
regulation of cellular amine metabolic processGO:0033238200.035
negative regulation of protein modification processGO:00314001630.034
Mouse
t cell activationGO:00421102890.034
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.034
Mouse
negative regulation of protein phosphorylationGO:00019331260.034
Mouse
homeostasis of number of cellsGO:00488722100.033
Mouse
regulation of membrane potentialGO:00423911920.033
Mouse
positive regulation of apoptotic processGO:00430652170.033
Mouse Fly
inflammatory responseGO:00069542440.032
Mouse
nucleoside phosphate metabolic processGO:00067533380.032
response to organonitrogen compoundGO:00102432460.032
Mouse
cellular nitrogen compound catabolic processGO:00442702800.032
Mouse
response to oxidative stressGO:00069791230.031
Mouse
skeletal system developmentGO:00015013560.031
regulation of cellular catabolic processGO:00313292420.030
Mouse Fly
spermatogenesisGO:00072832840.030
Fly
positive regulation of cell deathGO:00109422240.030
Mouse Fly
positive regulation of cellular amino acid metabolic processGO:004576430.030
t cell proliferationGO:00420981200.030
Mouse
positive regulation of defense responseGO:00313491240.029
regulation of secretion by cellGO:19035302490.029
Mouse
organonitrogen compound biosynthetic processGO:19015661920.029
positive regulation of protein phosphorylationGO:00019342420.029
positive regulation of cytokine productionGO:00018191740.029
Mouse
immune response regulating signaling pathwayGO:00027641250.029
mapk cascadeGO:00001652810.029
regulation of inflammatory responseGO:00507271470.028
Mouse
cytoplasmic transportGO:00164822340.028
leukocyte mediated immunityGO:00024431740.028
aromatic compound catabolic processGO:00194392860.028
Mouse
macromolecule catabolic processGO:00090572810.028
Mouse
negative regulation of kinase activityGO:0033673810.028
Mouse
cellular response to cytokine stimulusGO:00713451890.028
defense response to other organismGO:00985421970.027
small gtpase mediated signal transductionGO:0007264970.027
regulation of innate immune responseGO:0045088910.027
lymphocyte mediated immunityGO:00024491390.027
regulation of t cell activationGO:00508631700.026
Mouse
activation of immune responseGO:00022531380.026
regulation of mapk cascadeGO:00434082480.026
ossificationGO:00015032160.026
cellular chemical homeostasisGO:00550822150.026
positive regulation of programmed cell deathGO:00430682180.026
Mouse Fly
purine containing compound metabolic processGO:00725213110.026
cation homeostasisGO:00550802120.025
regulation of protein localizationGO:00328802310.025
Mouse
fatty acid metabolic processGO:00066311210.025
purine nucleoside triphosphate catabolic processGO:00091462030.025
leukocyte proliferationGO:00706611720.025
Mouse
regulation of secretionGO:00510462740.025
Mouse
transmembrane transportGO:00550854120.025
purine nucleotide metabolic processGO:00061633020.025
negative regulation of defense responseGO:0031348770.024
ras protein signal transductionGO:0007265770.024
wound healingGO:00420601570.024
monocarboxylic acid metabolic processGO:00327871910.024
cellular response to dna damage stimulusGO:00069742070.024
Mouse
regulation of protein kinase activityGO:00458592320.024
Mouse
purine nucleotide catabolic processGO:00061952110.024
positive regulation of cellular amine metabolic processGO:003324050.024
cellular response to molecule of bacterial originGO:0071219830.024
hematopoietic progenitor cell differentiationGO:00022441430.023
leukocyte mediated cytotoxicityGO:0001909620.023
regulation of peptidase activityGO:0052547960.023
Mouse Fly
negative regulation of intracellular signal transductionGO:19025321670.023
mitochondrion organizationGO:00070051340.023
Mouse
cellular response to lipopolysaccharideGO:0071222770.023
positive regulation of protein transportGO:0051222930.023
Mouse
negative regulation of lymphocyte activationGO:0051250910.022
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.022
production of molecular mediator of immune responseGO:00024401030.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
carbohydrate derivative biosynthetic processGO:19011371830.022
ion transmembrane transportGO:00342203610.022
lipid biosynthetic processGO:00086101790.022
sequestering of metal ionGO:0051238190.022
lipid transportGO:0006869980.022
cellular response to biotic stimulusGO:0071216920.021
myeloid cell differentiationGO:00300992330.021
Mouse
endomembrane system organizationGO:00102561470.021
cellular homeostasisGO:00197252400.021
positive regulation of secretionGO:00510471300.021
Mouse
regulation of cellular response to stressGO:00801351590.021
Fly
regulation of protein maturationGO:1903317960.021
nitrogen compound transportGO:00717052710.021
reactive oxygen species metabolic processGO:0072593840.021
nucleoside triphosphate metabolic processGO:00091412300.021
positive regulation of hydrolase activityGO:00513451480.020
Mouse Fly
sequestering of calcium ionGO:0051208180.020
lymphocyte proliferationGO:00466511640.020
Mouse
purine ribonucleotide catabolic processGO:00091542080.020
regulation of leukocyte mediated immunityGO:00027031040.020
nucleoside phosphate catabolic processGO:19012922220.020
positive regulation of mapk cascadeGO:00434101700.019
ear developmentGO:00435832000.019
positive regulation of apoptotic signaling pathwayGO:2001235950.019
Mouse Fly
cation transmembrane transportGO:00986552660.019
regulation of map kinase activityGO:00434051200.019
negative regulation of cell activationGO:00508661110.019
Mouse
carboxylic acid catabolic processGO:0046395510.019
regulation of adaptive immune responseGO:0002819900.019
divalent inorganic cation transportGO:00725111780.019
blood circulationGO:00080151950.019
muscle system processGO:00030121410.019
negative regulation of phosphorylationGO:00423261660.018
Mouse
bone developmentGO:00603481200.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
regulation of response to woundingGO:19030341890.018
Mouse
skeletal system morphogenesisGO:00487052030.018
regulation of ossificationGO:00302781120.018
glycosyl compound metabolic processGO:19016572460.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
regulation of apoptotic signaling pathwayGO:20012331970.018
Mouse Fly
carbohydrate metabolic processGO:00059752300.018
protein modification by small protein conjugation or removalGO:00706472070.018
protein catabolic processGO:00301632210.018
cellular response to extracellular stimulusGO:0031668810.018
Fly
cytokine mediated signaling pathwayGO:00192211150.018
regulation of organelle organizationGO:00330432890.018
regulation of protein processingGO:0070613960.018
nucleoside metabolic processGO:00091162460.018
ribonucleotide metabolic processGO:00092592910.018
glycosyl compound catabolic processGO:19016582060.018
anion transportGO:00068201770.018
positive regulation of transferase activityGO:00513471670.018
peptidyl amino acid modificationGO:00181933360.018
lung developmentGO:00303241640.017
organelle assemblyGO:00709251770.017
ribonucleoside metabolic processGO:00091192450.017
sensory perceptionGO:00076002450.017
Mouse
organophosphate biosynthetic processGO:00904071220.017
regulation of cell cycleGO:00517262810.017
Mouse
organonitrogen compound catabolic processGO:19015652640.017
cytokine secretionGO:0050663720.017
Mouse
embryonic organ morphogenesisGO:00485622760.017
nucleotide catabolic processGO:00091662170.017
myeloid leukocyte differentiationGO:00025731190.017
Mouse
reactive nitrogen species metabolic processGO:200105700.017
muscle contractionGO:00069361010.017
organic acid catabolic processGO:0016054510.017
regulation of neuron differentiationGO:00456642810.017
metal ion homeostasisGO:00550651890.017
regulation of establishment of protein localizationGO:00702011810.017
Mouse
response to hypoxiaGO:0001666580.017
Mouse
purine nucleoside metabolic processGO:00422782410.017
regulation of protein transportGO:00512231630.017
Mouse
purine nucleoside catabolic processGO:00061522050.017
sphingolipid biosynthetic processGO:0030148260.017
nucleotide metabolic processGO:00091173320.017
carbohydrate derivative catabolic processGO:19011362310.017
organic anion transportGO:00157111370.017
sulfur compound metabolic processGO:00067901000.016
spermatid differentiationGO:00485151150.016
Fly
positive regulation of immune effector processGO:00026991070.016
response to nutrient levelsGO:00316671090.016
Fly
respiratory tube developmentGO:00303231670.016
divalent inorganic cation homeostasisGO:00725071380.016
small molecule catabolic processGO:0044282710.016
immune response activating signal transductionGO:00027571160.016
organic hydroxy compound metabolic processGO:19016152030.016
negative regulation of cellular component organizationGO:00511291940.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
positive regulation of map kinase activityGO:0043406840.016
nucleoside catabolic processGO:00091642060.016
nucleoside triphosphate catabolic processGO:00091432050.016
synaptic transmissionGO:00072683290.016
Fly
ribose phosphate metabolic processGO:00196932910.016
reactive oxygen species biosynthetic processGO:190340980.016
response to reactive oxygen speciesGO:0000302560.016
epithelial tube morphogenesisGO:00605623030.016
Mouse
response to extracellular stimulusGO:00099911270.016
Fly
positive regulation of cell developmentGO:00107202370.016
Fly
positive regulation of t cell mediated cytotoxicityGO:0001916150.016
posttranscriptional regulation of gene expressionGO:00106081550.015
purine containing compound catabolic processGO:00725232130.015
intracellular protein transportGO:00068862040.015
smoothened signaling pathwayGO:00072241050.015
protein secretionGO:00093061110.015
Mouse
regulation of leukocyte proliferationGO:00706631210.015
Mouse
lateral inhibitionGO:004633110.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
Mouse
striated muscle contractionGO:0006941450.015
negative regulation of protein processingGO:0010955790.015
rhythmic processGO:00485111740.015
muscle cell differentiationGO:00426922610.015
cellular ion homeostasisGO:00068731650.015
dephosphorylationGO:00163111290.015
negative regulation of leukocyte proliferationGO:0070664460.015
Mouse
lymphocyte differentiationGO:00300982420.015
g protein coupled receptor signaling pathwayGO:00071862430.015
leukocyte apoptotic processGO:0071887710.015
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.015
adaptive immune responseGO:00022501550.015
regulation of t cell proliferationGO:0042129920.015
Mouse
purine ribonucleoside metabolic processGO:00461282410.015
guanosine containing compound catabolic processGO:19010691440.015
organic hydroxy compound transportGO:0015850930.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
regulation of interleukin 8 productionGO:003267730.015
organelle localizationGO:00516401790.015
multicellular organismal homeostasisGO:00488711640.015
regulation of lymphocyte mediated immunityGO:0002706840.015
negative regulation of immune effector processGO:0002698550.015
cation transportGO:00068123990.015
regulation of cytokine secretionGO:0050707610.015
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
organic acid transportGO:00158491010.015
regulation of body fluid levelsGO:00508781620.015
response to growth factorGO:00708481980.015
defense response to bacteriumGO:00427421190.015
hexose metabolic processGO:0019318980.014
organophosphate catabolic processGO:00464342320.014
membrane depolarizationGO:0051899640.014
Mouse
calcium ion homeostasisGO:00550741270.014
regulation of protein catabolic processGO:00421761080.014
lymphocyte homeostasisGO:0002260640.014
Mouse
negative regulation of protein maturationGO:1903318790.014
positive regulation of secretion by cellGO:19035321140.014
Mouse
regulation of kinase activityGO:00435492490.014
Mouse
wnt signaling pathwayGO:00160551880.014
cell killingGO:0001906670.014
positive regulation of interleukin 1 alpha productionGO:003273040.014
Mouse
chemotaxisGO:00069352470.014
respiratory system developmentGO:00605411900.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
response to inorganic substanceGO:0010035960.014
regulation of protein secretionGO:0050708820.014
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.014
cell activation involved in immune responseGO:00022631260.014
purine ribonucleoside catabolic processGO:00461302050.014
extracellular matrix organizationGO:00301981470.014
glycoprotein metabolic processGO:00091001160.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
cellular lipid catabolic processGO:0044242520.014
rho protein signal transductionGO:0007266320.014
ribonucleoside catabolic processGO:00424542060.014
lipid localizationGO:00108761260.014
regulation of system processGO:00440572000.014
regulation of hormone levelsGO:00108172110.014
divalent metal ion transportGO:00708381720.014
purine ribonucleotide metabolic processGO:00091502900.013
urogenital system developmentGO:00016552610.013
microtubule based processGO:00070172360.013
regulation of lymphocyte proliferationGO:00506701170.013
Mouse
carbohydrate homeostasisGO:00335001280.013
interleukin 1 productionGO:0032612310.013
Mouse
regulation of interleukin 1 beta productionGO:0032651250.013
Mouse
regulation of interferon gamma productionGO:0032649570.013
exocytosisGO:00068871210.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
forebrain developmentGO:00309003020.013
extracellular structure organizationGO:00430621480.013
methylationGO:00322591340.013
regulation of vesicle mediated transportGO:00606271390.013
positive regulation of innate immune responseGO:0045089800.013
negative regulation of cellular amine metabolic processGO:003323910.013
response to oxygen levelsGO:0070482620.013
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.013
Mouse
canonical wnt signaling pathwayGO:00600701300.013
asymmetric stem cell divisionGO:009872230.013
regulation of proteolysisGO:00301621640.013
Mouse Fly
myeloid cell homeostasisGO:00022621140.013
positive regulation of nervous system developmentGO:00519622210.013
fertilizationGO:00095661270.013
cell adhesionGO:00071553290.013
cellular response to hormone stimulusGO:00328701500.013
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.013
ribonucleotide catabolic processGO:00092612080.013
regulation of intracellular transportGO:00323861590.013
regulation of endopeptidase activityGO:0052548890.013
Mouse Fly
i kappab kinase nf kappab signalingGO:0007249850.013
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of interleukin 1 alpha productionGO:003265040.013
Mouse
circulatory system processGO:00030131970.013
small molecule biosynthetic processGO:00442831320.013
epithelial cell proliferationGO:00506731740.013
b cell proliferationGO:0042100530.013
Mouse
regulation of cell projection organizationGO:00313442060.013
leukocyte homeostasisGO:0001776790.012
Mouse
response to light stimulusGO:00094161350.012
Mouse
compound eye developmentGO:004874910.012
Fly
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
germ cell developmentGO:00072811850.012
Fly
positive regulation of kinase activityGO:00336741550.012
response to acid chemicalGO:00011011110.012
gland developmentGO:00487323300.012
Fly
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.012
rna processingGO:00063961050.012
lipid catabolic processGO:0016042690.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
positive regulation of protein kinase activityGO:00458601440.012
cell type specific apoptotic processGO:00972852680.012
Mouse Fly
angiogenesisGO:00015252010.012
Mouse
spermatid developmentGO:00072861080.012
positive regulation of leukocyte differentiationGO:1902107860.012
activation of cysteine type endopeptidase activityGO:0097202270.012
Mouse
cellular response to organic cyclic compoundGO:0071407870.012
Mouse
glucose homeostasisGO:00425931280.012
cellular response to external stimulusGO:0071496880.012
Fly
cellular metal ion homeostasisGO:00068751510.012
regulation of neuron projection developmentGO:00109751690.012
gtp metabolic processGO:00460391440.012
negative regulation of protein serine threonine kinase activityGO:0071901490.012
Mouse
retrograde transport endosome to golgiGO:004214720.012
regulation of leukocyte differentiationGO:19021051590.012
regulation of myeloid cell differentiationGO:0045637960.012
membrane organizationGO:00610242450.012
developmental maturationGO:00217001930.012
Fly
cellular response to oxidative stressGO:0034599760.012
Mouse
regulation of b cell activationGO:0050864810.012
Mouse
axonogenesisGO:00074092740.012
histone modificationGO:00165701590.012
cellular protein complex assemblyGO:00436231160.012
interleukin 6 productionGO:0032635580.012
t cell differentiationGO:00302171740.012
transmission of nerve impulseGO:0019226760.012
stem cell differentiationGO:00488632680.012
antigen receptor mediated signaling pathwayGO:0050851640.012
negative regulation of cytokine productionGO:0001818840.012
regulation of cell killingGO:0031341400.012
positive regulation of lymphocyte activationGO:00512511400.012
positive regulation of interleukin 1 alpha secretionGO:005071730.012
Mouse
anatomical structure homeostasisGO:00602491450.012
response to starvationGO:0042594650.012
Fly
developmental growth involved in morphogenesisGO:00605601380.012
interleukin 1 beta productionGO:0032611300.012
Mouse
inorganic cation transmembrane transportGO:00986622070.012
cellular macromolecule catabolic processGO:00442652060.012
Mouse
striated muscle tissue developmentGO:00147062930.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
cellular component assembly involved in morphogenesisGO:00109271390.011
maintenance of locationGO:0051235890.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
Mouse Fly
negative regulation of mapk cascadeGO:0043409650.011
carboxylic acid transportGO:00469421000.011
morphogenesis of a branching epitheliumGO:00611381930.011
peptide transportGO:00158331330.011
interleukin 8 productionGO:003263740.011
positive regulation of interleukin 1 beta productionGO:0032731160.011
Mouse
t cell mediated immunityGO:0002456500.011
immune response regulating cell surface receptor signaling pathwayGO:0002768800.011
macromolecular complex disassemblyGO:0032984430.011
striated muscle cell developmentGO:00550021250.011
cellular calcium ion homeostasisGO:00068741190.011
regulation of cell migrationGO:00303342190.011
mrna metabolic processGO:0016071840.011
cofactor metabolic processGO:0051186800.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
embryonic epithelial tube formationGO:00018381300.011
Mouse
positive regulation of cellular catabolic processGO:00313311480.011
Fly
peptide secretionGO:00027901140.011
steroid metabolic processGO:00082021190.011
b cell activationGO:00421131610.011
Mouse
guanosine containing compound metabolic processGO:19010681440.011
positive regulation of neuron differentiationGO:00456661410.011
erythrocyte differentiationGO:0030218880.011
action potentialGO:0001508780.011
positive regulation of lymphocyte mediated immunityGO:0002708620.011
blood vessel morphogenesisGO:00485142850.011
Mouse
mitotic cell cycle processGO:19030471590.011
regulation of homeostatic processGO:00328441820.011
regulation of stress activated mapk cascadeGO:0032872690.011
hemostasisGO:0007599780.011
cell substrate adhesionGO:00315891300.011
regulation of cell motilityGO:20001452360.011
tumor necrosis factor superfamily cytokine productionGO:0071706510.010
fat soluble vitamin biosynthetic processGO:004236240.010
interferon gamma productionGO:0032609670.010
peptidyl tyrosine phosphorylationGO:00181081430.010
blood coagulationGO:0007596760.010
organism emergence from protective structureGO:007168440.010
membrane lipid biosynthetic processGO:0046467320.010
digestive system developmentGO:00551232000.010
protein localization to organelleGO:00333651850.010
negative regulation of cell developmentGO:00107211690.010
regulation of striated muscle cell differentiationGO:0051153810.010
cell growthGO:00160491300.010
negative regulation of t cell activationGO:0050868650.010
Mouse
pharynx developmentGO:006046510.010
positive regulation of t cell activationGO:00508701010.010
placenta developmentGO:00018901400.010
calcium ion transportGO:00068161590.010
negative regulation of protein catabolic processGO:0042177360.010
nucleic acid phosphodiester bond hydrolysisGO:0090305490.010
Mouse
regulation of purine nucleotide metabolic processGO:19005421690.010
cofactor transportGO:005118140.010
renal system developmentGO:00720012250.010
male sex differentiationGO:00466611090.010
positive regulation of interleukin 8 productionGO:003275720.010
t cell homeostasisGO:0043029350.010
Mouse
b cell differentiationGO:0030183780.010
tissue homeostasisGO:00018941150.010
synaptic vesicle localizationGO:0097479590.010
protein complex disassemblyGO:0043241400.010
negative regulation of proteolysisGO:0045861740.010
innate immune response activating signal transductionGO:0002758500.010
establishment of organelle localizationGO:00516561220.010
multicellular organismal signalingGO:0035637910.010

Casp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
immune system diseaseDOID:291400.011