Mus musculus

61 known processes

Casp2

caspase 2

(Aliases: Caspase-2,ICH-1,Nedd2)

Casp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecule catabolic processGO:00090572810.342
Mouse Worm
histone methylationGO:0016571710.174
cellular nitrogen compound catabolic processGO:00442702800.168
Mouse
regulation of chromatin silencingGO:003193520.162
negative regulation of cellular protein metabolic processGO:00322692470.149
Mouse
cellular macromolecule catabolic processGO:00442652060.135
Mouse
cellular amine metabolic processGO:0044106440.124
heterocycle catabolic processGO:00467002800.110
Mouse
germ cell developmentGO:00072811850.099
Fly
amine metabolic processGO:0009308450.097
cellular amino acid metabolic processGO:00065201030.095
regulation of cellular catabolic processGO:00313292420.086
Mouse Fly
regulation of cellular ketone metabolic processGO:0010565660.084
development of primary sexual characteristicsGO:00451371430.084
Rat
gene silencingGO:0016458380.084
regulation of cellular amine metabolic processGO:0033238200.081
regulation of cellular amino acid metabolic processGO:000652150.078
cellular protein catabolic processGO:00442571550.077
regulation of protein stabilityGO:0031647520.073
gonad morphogenesisGO:003526210.072
signal transduction involved in dna damage checkpointGO:007242230.067
Human
rhythmic processGO:00485111740.067
Rat
intrinsic apoptotic signaling pathwayGO:00971931320.067
Mouse
regulation of cell cycleGO:00517262810.065
Human Mouse
negative regulation of protein metabolic processGO:00512482820.062
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.061
response to lipopolysaccharideGO:00324961280.061
Mouse
nucleotide metabolic processGO:00091173320.059
chromatin modificationGO:00165681870.059
male gamete generationGO:00482322850.058
Fly
leukocyte differentiationGO:00025213420.058
Mouse
developmental maturationGO:00217001930.058
Fly
negative regulation of molecular functionGO:00440922580.057
Mouse
mitotic cell cycle processGO:19030471590.057
Human
response to molecule of bacterial originGO:00022371430.057
Mouse
macromolecule methylationGO:00434141200.057
proteolysis involved in cellular protein catabolic processGO:00516031470.056
apoptotic signaling pathwayGO:00971903060.056
rna 3 end processingGO:0031123200.054
cellular ketone metabolic processGO:0042180840.053
negative regulation of cellular component organizationGO:00511291940.053
nucleobase containing small molecule metabolic processGO:00550863520.052
regulation of cell cycle processGO:00105641600.052
Human
skeletal system developmentGO:00015013560.052
epithelial tube formationGO:00721751300.047
Mouse
methylationGO:00322591340.046
purine containing compound metabolic processGO:00725213110.045
purine ribonucleotide metabolic processGO:00091502900.045
histone lysine methylationGO:0034968500.045
regulation of chromatin modificationGO:1903308570.045
dna metabolic processGO:00062593030.044
Mouse
regulation of organelle organizationGO:00330432890.042
histone h3 k9 dimethylationGO:003612340.041
purine nucleotide metabolic processGO:00061633020.041
circulatory system processGO:00030131970.040
tube formationGO:00351481400.039
Mouse
rna processingGO:00063961050.038
multicellular organism growthGO:00352641610.037
peptidyl amino acid modificationGO:00181933360.037
protein polyubiquitinationGO:0000209330.036
purine nucleoside triphosphate metabolic processGO:00091442260.035
endomembrane system organizationGO:00102561470.034
response to organic cyclic compoundGO:00140701980.034
Mouse
chromatin organizationGO:00063252060.034
negative regulation of translationGO:0017148220.034
regulation of cell cycle g2 m phase transitionGO:1902749100.034
protein methylationGO:0006479810.033
histone modificationGO:00165701590.033
regulation of apoptotic signaling pathwayGO:20012331970.032
ossificationGO:00015032160.032
cellular response to dna damage stimulusGO:00069742070.032
Human Mouse
epithelial tube morphogenesisGO:00605623030.032
Mouse
negative regulation of protein modification processGO:00314001630.031
Mouse
regulation of myeloid cell differentiationGO:0045637960.031
blood circulationGO:00080151950.031
aromatic compound catabolic processGO:00194392860.030
Mouse
dna alkylationGO:0006305430.030
cardiac muscle contractionGO:0060048320.030
organelle fissionGO:00482851700.029
glycosyl compound metabolic processGO:19016572460.029
negative regulation of cellular amine metabolic processGO:003323910.029
ribonucleoside metabolic processGO:00091192450.029
regulation of chromatin organizationGO:1902275570.029
heart contractionGO:0060047930.029
regulation of circadian rhythmGO:0042752580.029
negative regulation of organelle organizationGO:0010639900.029
modification dependent macromolecule catabolic processGO:00436321330.029
oocyte axis specificationGO:000730920.028
organophosphate biosynthetic processGO:00904071220.028
spermatogenesisGO:00072832840.028
Fly
modification dependent protein catabolic processGO:00199411330.028
peptidyl lysine modificationGO:0018205770.027
organelle assemblyGO:00709251770.027
meiotic cell cycleGO:00513211220.027
posttranscriptional regulation of gene expressionGO:00106081550.027
embryonic epithelial tube formationGO:00018381300.027
Mouse
nucleoside metabolic processGO:00091162460.025
hematopoietic progenitor cell differentiationGO:00022441430.025
meiotic nuclear divisionGO:00071261150.025
translationGO:0006412930.025
heart processGO:0003015940.024
protein localization to organelleGO:00333651850.024
positive regulation of neuron differentiationGO:00456661410.024
cell maturationGO:00484691270.023
Fly
regulation of histone modificationGO:0031056560.023
regulation of organ morphogenesisGO:20000271440.023
Fly
positive regulation of nervous system developmentGO:00519622210.023
oxidation reduction processGO:00551143420.023
spermatid developmentGO:00072861080.023
Fly
localization within membraneGO:005166840.023
nucleoside catabolic processGO:00091642060.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.023
protein modification by small protein conjugationGO:00324461870.022
negative regulation of histone h3 k9 methylationGO:005157340.022
purine ribonucleoside monophosphate metabolic processGO:0009167800.022
carbohydrate homeostasisGO:00335001280.022
camera type eye developmentGO:00430102660.022
Rat
cellular homeostasisGO:00197252400.022
histone acetylationGO:0016573410.022
dna integrity checkpointGO:0031570280.022
Human
negative regulation of cellular amino acid metabolic processGO:004576300.022
response to alcoholGO:0097305480.022
Mouse
organic cyclic compound catabolic processGO:19013612950.022
Mouse
ribose phosphate metabolic processGO:00196932910.022
protein modification by small protein conjugation or removalGO:00706472070.021
female gamete generationGO:0007292740.021
Fly
response to radiationGO:00093141650.021
Mouse
regulation of neuron differentiationGO:00456642810.021
myeloid cell homeostasisGO:00022621140.020
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.020
Mouse
muscle tissue developmentGO:00605373080.020
purine ribonucleoside metabolic processGO:00461282410.020
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.020
circadian rhythmGO:00076231140.020
nucleoside phosphate metabolic processGO:00067533380.020
muscle contractionGO:00069361010.020
dna repairGO:00062811070.020
circadian regulation of gene expressionGO:0032922480.020
microtubule cytoskeleton organizationGO:00002261570.020
nucleoside phosphate catabolic processGO:19012922220.020
divalent metal ion transportGO:00708381720.020
negative regulation of cell developmentGO:00107211690.020
striated muscle contractionGO:0006941450.019
histone h4 k16 acetylationGO:004398430.019
cellular lipid metabolic processGO:00442553230.019
protein catabolic processGO:00301632210.019
Worm
spermatid differentiationGO:00485151150.019
Fly
positive regulation of cell cycle processGO:0090068610.019
Human
canonical wnt signaling pathwayGO:00600701300.019
ribonucleotide metabolic processGO:00092592910.019
regulation of hormone levelsGO:00108172110.019
cell type specific apoptotic processGO:00972852680.019
Mouse Rat Fly
regulation of cell divisionGO:0051302760.019
regulation of histone h3 k9 methylationGO:005157080.019
mrna 3 end processingGO:0031124160.019
carbohydrate derivative biosynthetic processGO:19011371830.018
lymphocyte differentiationGO:00300982420.018
response to extracellular stimulusGO:00099911270.018
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.018
negative regulation of chromatin silencingGO:003193610.018
protein secretionGO:00093061110.018
Mouse
protein maturationGO:00516041760.018
Human Mouse Worm Fly
oocyte anterior posterior axis specificationGO:000731420.018
b cell activationGO:00421131610.018
Mouse
purine nucleoside catabolic processGO:00061522050.018
mitotic cell cycleGO:00002781950.018
Human
negative regulation of cell proliferationGO:00082852960.018
Mouse Fly
purine nucleoside monophosphate metabolic processGO:0009126810.018
asymmetric neuroblast divisionGO:005505910.017
microtubule based processGO:00070172360.017
covalent chromatin modificationGO:00165691630.017
ion transmembrane transportGO:00342203610.017
innate immune responseGO:00450871570.017
Fly
purine nucleoside metabolic processGO:00422782410.017
sulfur compound metabolic processGO:00067901000.017
regulation of mrna stabilityGO:0043488230.017
negative regulation of nervous system developmentGO:00519611560.017
response to transforming growth factor betaGO:0071559880.017
skeletal muscle cell differentiationGO:0035914660.017
cellular response to transforming growth factor beta stimulusGO:0071560880.017
amp metabolic processGO:004603340.017
nucleus organizationGO:0006997450.016
protein alkylationGO:0008213810.016
negative regulation of histone methylationGO:0031061100.016
purine containing compound catabolic processGO:00725232130.016
cytokine productionGO:00018163190.016
Mouse
regulation of multi organism processGO:00439001110.016
Fly
sensory organ morphogenesisGO:00905962420.016
Fly
regulation of system processGO:00440572000.016
regulation of cellular component biogenesisGO:00440871810.016
nuclear transcribed mrna poly a tail shorteningGO:000028970.016
regulation of cell activationGO:00508652890.016
Mouse
axonogenesisGO:00074092740.016
cation transmembrane transportGO:00986552660.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
rna catabolic processGO:0006401290.016
dna templated transcriptional preinitiation complex assemblyGO:007089740.016
immune effector processGO:00022523210.016
Fly
purine nucleotide catabolic processGO:00061952110.016
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.016
nucleoside phosphate biosynthetic processGO:1901293790.016
transmembrane transportGO:00550854120.016
membrane organizationGO:00610242450.016
Worm
purine nucleoside triphosphate catabolic processGO:00091462030.016
regulation of blood circulationGO:1903522930.016
negative regulation of cell cycle processGO:0010948690.015
Human
mitotic chromosome condensationGO:000707610.015
gonad developmentGO:00084061410.015
Rat
glial cell apoptotic processGO:003434930.015
Mouse
protein deacetylationGO:0006476320.015
negative regulation of gene silencingGO:006096920.015
cell growthGO:00160491300.015
cellular response to organonitrogen compoundGO:00714171450.015
protein acylationGO:0043543640.015
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.015
protein ubiquitinationGO:00165671710.015
regulation of establishment of protein localizationGO:00702011810.015
Mouse
regulation of purine nucleotide metabolic processGO:19005421690.015
negative regulation of neuron differentiationGO:00456651010.015
divalent inorganic cation transportGO:00725111780.015
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.015
regulation of asymmetric cell divisionGO:000978640.015
positive regulation of protein modification processGO:00314012990.015
somatic diversification of immune receptors via somatic mutationGO:000256680.015
organophosphate catabolic processGO:00464342320.015
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.015
response to organonitrogen compoundGO:00102432460.015
Mouse
regulation of mitotic cell cycleGO:00073461260.015
Human
ribonucleoside triphosphate metabolic processGO:00091992200.015
nuclear divisionGO:00002801580.015
response to nutrient levelsGO:00316671090.014
neural tube developmentGO:00219151600.014
Mouse
rna interferenceGO:001624620.014
cell junction organizationGO:0034330770.014
nitrogen compound transportGO:00717052710.014
lung developmentGO:00303241640.014
glucose homeostasisGO:00425931280.014
positive regulation of proteolysisGO:0045862850.014
Mouse Fly
negative regulation of transcription from rna polymerase i promoterGO:001647920.014
peptidyl lysine methylationGO:0018022290.014
myeloid cell differentiationGO:00300992330.014
Mouse
pharynx developmentGO:006046510.014
positive regulation of cell developmentGO:00107202370.014
Fly
lateral inhibitionGO:004633110.014
positive regulation of cell deathGO:00109422240.014
muscle cell differentiationGO:00426922610.014
nucleoside monophosphate metabolic processGO:0009123850.014
nucleoside bisphosphate biosynthetic processGO:003386660.014
positive regulation of cellular amine metabolic processGO:003324050.014
histone h3 k9 methylationGO:0051567170.013
immunoglobulin productionGO:0002377730.013
regulation of cytoplasmic mrna processing body assemblyGO:001060320.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
learning or memoryGO:00076111480.013
positive regulation of apoptotic processGO:00430652170.013
negative regulation of ossificationGO:0030279490.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
morphogenesis of a branching epitheliumGO:00611381930.013
mitotic nuclear divisionGO:0007067480.013
production of molecular mediator of immune responseGO:00024401030.013
Fly
wound healingGO:00420601570.013
glycerolipid metabolic processGO:00464861220.013
positive regulation of hydrolase activityGO:00513451480.013
Mouse Fly
skeletal system morphogenesisGO:00487052030.013
positive regulation of defense responseGO:00313491240.013
Fly
dna modificationGO:0006304500.013
asymmetric stem cell divisionGO:009872230.013
gland developmentGO:00487323300.013
Fly
respiratory tube developmentGO:00303231670.013
organonitrogen compound catabolic processGO:19015652640.013
positive regulation of cell cycleGO:0045787920.013
Human
response to heatGO:0009408270.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
oocyte constructionGO:000730820.012
definitive hemopoiesisGO:0060216200.012
maternal determination of anterior posterior axis embryoGO:000835820.012
protein localization to nucleusGO:00345041210.012
signal transduction involved in dna integrity checkpointGO:007240130.012
Human
anatomical structure homeostasisGO:00602491450.012
regulation of protein transportGO:00512231630.012
Mouse
regulation of rna stabilityGO:0043487260.012
developmental growth involved in morphogenesisGO:00605601380.012
proteasomal protein catabolic processGO:0010498980.012
regulation of inflammatory responseGO:00507271470.012
Mouse
regulation of heart contractionGO:0008016770.012
protein processingGO:00164851630.012
Human Mouse Worm Fly
ribonucleoside monophosphate metabolic processGO:0009161800.012
germ line stem cell divisionGO:004207820.012
signal transduction involved in mitotic dna damage checkpointGO:190240230.012
Human
negative regulation of phagocytosisGO:005076540.012
ribonucleotide biosynthetic processGO:0009260590.012
negative regulation of cell activationGO:00508661110.012
Mouse
inflammatory responseGO:00069542440.012
Mouse
embryonic organ morphogenesisGO:00485622760.012
dendrite developmentGO:00163581150.012
Fly
establishment or maintenance of cytoskeleton polarityGO:003095220.012
carbohydrate derivative catabolic processGO:19011362310.012
regulation of neuron projection developmentGO:00109751690.012
response to temperature stimulusGO:0009266550.011
negative regulation of protein phosphorylationGO:00019331260.011
Mouse
organic hydroxy compound metabolic processGO:19016152030.011
Fly
establishment or maintenance of neuroblast polarityGO:004519610.011
receptor mediated endocytosisGO:0006898510.011
development of primary male sexual characteristicsGO:0046546880.011
cardiac muscle cell contractionGO:008600370.011
regulation of lymphocyte activationGO:00512492400.011
Mouse
developmental cell growthGO:0048588840.011
internal peptidyl lysine acetylationGO:0018393420.011
positive regulation of cellular catabolic processGO:00313311480.011
positive regulation of nucleoside metabolic processGO:0045979910.011
negative regulation of phosphate metabolic processGO:00459361840.011
Mouse
nuclear envelope organizationGO:0006998110.011
ribonucleoside biosynthetic processGO:0042455210.011
regulation of osteoblast differentiationGO:0045667670.011
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.011
macromolecular complex disassemblyGO:0032984430.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
peptidyl serine phosphorylationGO:0018105740.011
response to monosaccharideGO:0034284670.011
nucleocytoplasmic transportGO:00069131390.011
cytoplasmic transportGO:00164822340.011
nuclear transportGO:00511691390.011
regulation of cytoskeleton organizationGO:00514931220.011
negative regulation of gene expression epigeneticGO:0045814150.011
somatic cell dna recombinationGO:0016444510.011
positive regulation of myeloid cell differentiationGO:0045639430.011
neural precursor cell proliferationGO:00613511210.011
skeletal muscle organ developmentGO:00605381630.011
regulation of nucleotide catabolic processGO:00308111220.011
signal transduction involved in cell cycle checkpointGO:007239530.010
Human
inorganic cation transmembrane transportGO:00986622070.010
positive regulation of histone h3 k4 methylationGO:005157150.010
protein targetingGO:00066051430.010
response to endoplasmic reticulum stressGO:0034976530.010
Mouse
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.010
cation transportGO:00068123990.010
endocytosisGO:00068971680.010
Worm
cellular protein complex assemblyGO:00436231160.010
sulfur compound biosynthetic processGO:0044272370.010
neuron deathGO:00709971540.010
Mouse Rat
regulation of homeostatic processGO:00328441820.010
ribonucleoside bisphosphate metabolic processGO:003387590.010
establishment or maintenance of cell polarityGO:0007163860.010
mrna metabolic processGO:0016071840.010
kidney developmentGO:00018222130.010
megakaryocyte differentiationGO:0030219260.010
maintenance of locationGO:0051235890.010
tube closureGO:0060606910.010
cellular response to hormone stimulusGO:00328701500.010
Mouse
regulation of myeloid leukocyte differentiationGO:0002761580.010
cellular response to cytokine stimulusGO:00713451890.010

Casp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:15000.019
central nervous system diseaseDOID:33100.017
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
physical disorderDOID:008001500.010