Mus musculus

149 known processes

Casp8

caspase 8

(Aliases: CASP-8,Mch5,FLICE,MACH)

Casp8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of necroptotic processGO:0060544100.999
ripoptosome assembly involved in necroptotic processGO:190102660.999
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.999
necroptotic processGO:0070266210.999
regulation of defense responseGO:00313472330.988
Mouse
programmed necrotic cell deathGO:0097300280.973
t cell extravasationGO:007268340.972
cd8 positive alpha beta t cell extravasationGO:003569730.970
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.969
i kappab kinase nf kappab signalingGO:0007249850.961
Human Mouse
apoptotic signaling pathwayGO:00971903060.960
cd8 positive alpha beta cytotoxic t cell extravasationGO:003569820.935
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.920
regulation of cell activationGO:00508652890.911
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.897
positive regulation of t cell mediated cytotoxicityGO:0001916150.885
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.882
negative regulation of necrotic cell deathGO:0060547110.871
activation of immune responseGO:00022531380.869
necroptotic signaling pathwayGO:009752730.864
activation induced cell death of t cellsGO:0006924100.863
positive regulation of apoptotic signaling pathwayGO:2001235950.861
defense response to other organismGO:00985421970.839
leukocyte proliferationGO:00706611720.818
Mouse
regulation of necrotic cell deathGO:0010939130.808
t cell homeostasisGO:0043029350.792
Mouse
regulation of t cell proliferationGO:0042129920.780
Mouse
regulation of t cell mediated immunityGO:0002709340.752
t cell proliferationGO:00420981200.747
Mouse
positive regulation of cell deathGO:00109422240.744
t cell mediated cytotoxicityGO:0001913260.743
immune effector processGO:00022523210.734
lymphocyte proliferationGO:00466511640.729
Mouse
regulation of cytokine productionGO:00018172660.724
Mouse
negative regulation of immune system processGO:00026832090.724
Mouse
positive regulation of programmed cell deathGO:00430682180.721
regulation of leukocyte apoptotic processGO:2000106560.719
regulation of t cell mediated cytotoxicityGO:0001914180.717
intrinsic apoptotic signaling pathwayGO:00971931320.713
Mouse
necrotic cell deathGO:0070265300.713
t cell activationGO:00421102890.704
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.702
lymphocyte mediated immunityGO:00024491390.683
negative regulation of necroptotic processGO:006054690.678
leukocyte mediated immunityGO:00024431740.660
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.653
adaptive immune responseGO:00022501550.644
positive regulation of lymphocyte proliferationGO:0050671700.637
regulation of leukocyte proliferationGO:00706631210.635
Mouse
t cell mediated immunityGO:0002456500.629
lymphocyte differentiationGO:00300982420.627
lymphocyte homeostasisGO:0002260640.626
Mouse
positive regulation of apoptotic processGO:00430652170.626
cell killingGO:0001906670.619
positive regulation of defense responseGO:00313491240.603
regulation of protein localizationGO:00328802310.602
Mouse
positive regulation of innate immune responseGO:0045089800.599
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.597
spleen developmentGO:0048536390.579
regulation of lymphocyte proliferationGO:00506701170.566
Mouse
positive regulation of t cell activationGO:00508701010.560
t cell differentiation in thymusGO:0033077770.557
positive regulation of adaptive immune responseGO:0002821610.553
cytokine mediated signaling pathwayGO:00192211150.546
t cell differentiationGO:00302171740.546
jnk cascadeGO:0007254720.540
interleukin 2 productionGO:0032623330.539
positive regulation of jnk cascadeGO:0046330460.537
positive regulation of necrotic cell deathGO:001094010.525
regulation of alpha beta t cell activationGO:0046634530.524
cellular response to cytokine stimulusGO:00713451890.508
negative regulation of lymphocyte activationGO:0051250910.505
Mouse
cytokine productionGO:00018163190.505
Mouse
cell type specific apoptotic processGO:00972852680.503
regulation of leukocyte mediated cytotoxicityGO:0001910380.498
regulation of leukocyte differentiationGO:19021051590.497
Human
antigen receptor mediated signaling pathwayGO:0050851640.489
immune response regulating cell surface receptor signaling pathwayGO:0002768800.473
regulation of adaptive immune responseGO:0002819900.471
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.470
lymph node developmentGO:0048535180.470
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.464
macrophage differentiationGO:0030225200.461
defense response to bacteriumGO:00427421190.458
positive regulation of immune effector processGO:00026991070.455
stress activated protein kinase signaling cascadeGO:0031098810.443
t cell apoptotic processGO:0070231390.440
regulation of cysteine type endopeptidase activityGO:2000116650.431
t cell receptor signaling pathwayGO:0050852460.427
extrinsic apoptotic signaling pathwayGO:00971911260.425
regulation of innate immune responseGO:0045088910.419
leukocyte mediated cytotoxicityGO:0001909620.418
positive regulation of cytokine productionGO:00018191740.417
Mouse
innate immune responseGO:00450871570.414
response to interleukin 12GO:007067120.413
homeostasis of number of cellsGO:00488722100.407
Mouse
regulation of kinase activityGO:00435492490.405
Mouse
regulation of peptidase activityGO:0052547960.397
response to organic cyclic compoundGO:00140701980.396
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.396
regulation of lymphocyte activationGO:00512492400.396
Mouse
regulation of t cell extravasationGO:200040730.393
regulation of response to cytokine stimulusGO:0060759230.392
protein maturationGO:00516041760.390
response to molecule of bacterial originGO:00022371430.386
Mouse
reactive oxygen species metabolic processGO:0072593840.384
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.373
Mouse
immune response activating signal transductionGO:00027571160.372
positive regulation of t cell proliferationGO:0042102520.369
regulation of hydrolase activityGO:00513362460.355
positive regulation of leukocyte proliferationGO:0070665730.355
negative regulation of molecular functionGO:00440922580.352
Mouse
positive regulation of interleukin 2 productionGO:0032743190.347
immune response activating cell surface receptor signaling pathwayGO:0002429720.346
response to lipopolysaccharideGO:00324961280.341
Mouse
regulation of proteolysisGO:00301621640.337
regulation of tumor necrosis factor productionGO:0032680490.326
regulation of cell killingGO:0031341400.323
hepatocyte apoptotic processGO:0097284110.323
activation of cysteine type endopeptidase activityGO:0097202270.320
intracellular protein transportGO:00068862040.314
leukocyte differentiationGO:00025213420.311
regulation of activated t cell proliferationGO:0046006160.310
Mouse
immune response regulating signaling pathwayGO:00027641250.308
positive regulation of cell activationGO:00508671580.307
alpha beta t cell activationGO:0046631910.300
lymphocyte apoptotic processGO:0070227540.292
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.290
positive regulation of interleukin 8 productionGO:003275720.289
positive regulation of lymphocyte activationGO:00512511400.285
cellular response to lipopolysaccharideGO:0071222770.280
regulation of membrane potentialGO:00423911920.273
Mouse
aromatic compound catabolic processGO:00194392860.272
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.271
defense response to virusGO:0051607680.267
anion transportGO:00068201770.267
regulation of t cell apoptotic processGO:0070232280.264
leukocyte apoptotic processGO:0071887710.264
regulation of protein kinase activityGO:00458592320.262
Mouse
t cell migrationGO:0072678190.257
stress activated mapk cascadeGO:0051403800.256
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.256
regulation of cell cycleGO:00517262810.254
Mouse
positive regulation of interferon gamma productionGO:0032729390.252
regulation of lymphocyte mediated immunityGO:0002706840.251
regulation of t cell activationGO:00508631700.250
Mouse
positive regulation of t cell extravasationGO:200040920.250
positive regulation of hydrolase activityGO:00513451480.247
regulation of cell motilityGO:20001452360.247
cellular response to peptidoglycanGO:007122440.244
positive regulation of myeloid leukocyte differentiationGO:0002763260.243
Human
gland developmentGO:00487323300.236
regulation of alpha beta t cell proliferationGO:0046640180.233
regulation of endopeptidase activityGO:0052548890.233
regulation of homeostatic processGO:00328441820.232
innate immune response activating signal transductionGO:0002758500.231
positive regulation of response to cytokine stimulusGO:0060760110.231
protein autophosphorylationGO:0046777610.230
cellular ketone metabolic processGO:0042180840.230
regulation of sequence specific dna binding transcription factor activityGO:00510901060.230
lymphocyte migrationGO:0072676260.230
protein oligomerizationGO:0051259670.225
leukocyte migrationGO:00509001240.222
thymus developmentGO:0048538410.220
regulation of cell migrationGO:00303342190.220
epithelial tube morphogenesisGO:00605623030.217
positive regulation of cysteine type endopeptidase activityGO:2001056390.216
protein processingGO:00164851630.215
regulation of interleukin 8 productionGO:003267730.214
positive regulation of macrophage differentiationGO:004565150.212
Human
establishment of protein localization to organelleGO:00725941180.210
interleukin 8 productionGO:003263740.203
regulation of intracellular transportGO:00323861590.202
neuron apoptotic processGO:00514021420.201
Mouse
nik nf kappab signalingGO:0038061140.201
zymogen activationGO:0031638410.200
regulation of transferase activityGO:00513382630.200
Mouse
cellular response to oxidative stressGO:0034599760.198
Mouse
signal transduction in absence of ligandGO:0038034550.195
Mouse
tumor necrosis factor productionGO:0032640500.194
cellular response to biotic stimulusGO:0071216920.193
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.193
regulation of alpha beta t cell differentiationGO:0046637350.192
lymphocyte activation involved in immune responseGO:0002285930.189
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.187
regulation of interferon gamma productionGO:0032649570.187
regulation of interleukin 6 productionGO:0032675550.186
regulation of inflammatory responseGO:00507271470.186
Mouse
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.184
mapk cascadeGO:00001652810.182
nitrogen compound transportGO:00717052710.180
regulation of mapk cascadeGO:00434082480.179
cellular response to dna damage stimulusGO:00069742070.179
Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.177
regulation of intracellular protein transportGO:0033157820.174
response to growth factorGO:00708481980.173
blood vessel morphogenesisGO:00485142850.173
regulation of secretionGO:00510462740.170
Mouse
positive regulation of tumor necrosis factor productionGO:0032760300.169
regulation of lymphocyte apoptotic processGO:0070228410.169
positive regulation of mapk cascadeGO:00434101700.169
chemokine productionGO:0032602340.167
cell activation involved in immune responseGO:00022631260.163
leukocyte homeostasisGO:0001776790.163
Mouse
regulation of interleukin 2 productionGO:0032663280.160
cellular amine metabolic processGO:0044106440.158
positive regulation of alpha beta t cell differentiationGO:0046638280.156
cellular response to growth factor stimulusGO:00713631970.152
regulation of reactive oxygen species metabolic processGO:2000377400.152
protein import into nucleusGO:0006606950.148
tumor necrosis factor superfamily cytokine productionGO:0071706510.148
cellular extravasationGO:0045123170.147
myeloid cell differentiationGO:00300992330.145
regulation of myeloid leukocyte differentiationGO:0002761580.143
Human
glycoprotein biosynthetic processGO:0009101890.142
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.141
regulation of establishment of protein localizationGO:00702011810.138
Mouse
ripoptosome assemblyGO:009734360.136
epidermis developmentGO:00085441870.135
Mouse
activation of innate immune responseGO:0002218560.134
neuron deathGO:00709971540.131
Mouse
response to organonitrogen compoundGO:00102432460.130
Mouse
organic acid transportGO:00158491010.130
positive regulation of secretionGO:00510471300.130
Mouse
amine metabolic processGO:0009308450.129
regulation of cd4 positive alpha beta t cell activationGO:2000514240.128
antibacterial peptide productionGO:000277820.124
b cell activationGO:00421131610.121
Mouse
pattern recognition receptor signaling pathwayGO:0002221470.120
positive regulation of proteolysisGO:0045862850.119
organonitrogen compound biosynthetic processGO:19015661920.118
organic cyclic compound catabolic processGO:19013612950.116
Mouse
membrane organizationGO:00610242450.116
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.115
positive regulation of nf kappab transcription factor activityGO:0051092300.115
fibril organizationGO:009743520.114
cellular response to lipidGO:00713961450.114
Mouse
negative regulation of b cell activationGO:0050869270.114
Mouse
alpha beta t cell differentiationGO:0046632690.113
macromolecule deacylationGO:0098732370.112
carbohydrate derivative biosynthetic processGO:19011371830.108
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.107
positive regulation of type i interferon mediated signaling pathwayGO:006034040.107
peptide transportGO:00158331330.107
transmembrane transportGO:00550854120.106
ion transmembrane transportGO:00342203610.105
positive regulation of peptidase activityGO:0010952490.105
glycosyl compound metabolic processGO:19016572460.104
cation homeostasisGO:00550802120.102
intracellular receptor signaling pathwayGO:0030522740.101
glycoprotein metabolic processGO:00091001160.101
macromolecule catabolic processGO:00090572810.100
Human Mouse
negative regulation of phosphorus metabolic processGO:00105631840.100
Mouse
regulation of cellular ketone metabolic processGO:0010565660.100
positive regulation of endopeptidase activityGO:0010950430.099
lipid localizationGO:00108761260.097
multicellular organism growthGO:00352641610.097
negative regulation of homeostatic processGO:0032845710.096
protein homooligomerizationGO:0051260430.094
purine nucleotide metabolic processGO:00061633020.094
regulation of response to woundingGO:19030341890.092
Mouse
regulation of cellular catabolic processGO:00313292420.092
Mouse
positive regulation of protein transportGO:0051222930.091
Mouse
positive regulation of protein modification processGO:00314012990.091
peptidyl serine modificationGO:0018209830.090
positive regulation of t helper 1 cell differentiationGO:004562740.090
cellular response to molecule of bacterial originGO:0071219830.090
negative regulation of cell proliferationGO:00082852960.089
Mouse
cellular macromolecule catabolic processGO:00442652060.088
Human Mouse
cellular response to type i interferonGO:0071357100.087
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.086
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.086
cellular response to external stimulusGO:0071496880.085
Human
positive regulation of protein kinase activityGO:00458601440.084
regulation of protein deacetylationGO:0090311170.083
negative regulation of t cell apoptotic processGO:0070233180.083
erk1 and erk2 cascadeGO:0070371770.083
cellular amino acid metabolic processGO:00065201030.082
regulation of erk1 and erk2 cascadeGO:0070372710.082
cellular nitrogen compound catabolic processGO:00442702800.082
Mouse
positive regulation of t cell differentiationGO:0045582520.081
negative regulation of phosphorylationGO:00423261660.081
Mouse
cellular ion homeostasisGO:00068731650.079
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.078
spermatogenesisGO:00072832840.077
cytoplasmic transportGO:00164822340.077
nucleoside phosphate metabolic processGO:00067533380.077
autophagyGO:0006914450.077
Mouse
positive regulation of alpha beta t cell activationGO:0046635390.076
neural tube developmentGO:00219151600.076
regulation of antibacterial peptide productionGO:000278610.076
sensory perceptionGO:00076002450.075
Mouse
regulation of secretion by cellGO:19035302490.075
Mouse
protein localization to nucleusGO:00345041210.075
interferon gamma productionGO:0032609670.074
cd4 positive alpha beta t cell differentiationGO:0043367410.074
cellular response to organonitrogen compoundGO:00714171450.074
positive regulation of kinase activityGO:00336741550.073
negative regulation of cellular amine metabolic processGO:003323910.073
regulation of cellular amino acid metabolic processGO:000652150.071
regulation of interleukin 1 alpha productionGO:003265040.070
Mouse
peptidyl amino acid modificationGO:00181933360.069
regulation of immunological synapse formationGO:200052020.069
organic anion transportGO:00157111370.069
regulation of macrophage differentiationGO:004564990.069
Human
negative regulation of t cell activationGO:0050868650.068
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.068
Mouse
type i interferon productionGO:0032606290.068
positive regulation of transferase activityGO:00513471670.066
positive regulation of interleukin 6 productionGO:0032755370.066
negative regulation of phosphate metabolic processGO:00459361840.066
Mouse
regulation of protein transportGO:00512231630.066
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.066
positive regulation of leukocyte differentiationGO:1902107860.066
Human
forebrain developmentGO:00309003020.065
regulation of lymphocyte differentiationGO:00456191070.065
organonitrogen compound catabolic processGO:19015652640.064
regulation of defense response to bacteriumGO:190042430.064
maintenance of locationGO:0051235890.064
positive regulation of lymphocyte differentiationGO:0045621610.064
positive regulation of intracellular transportGO:0032388700.063
protein targetingGO:00066051430.063
positive regulation of leukocyte mediated immunityGO:0002705700.062
sequestering of calcium ionGO:0051208180.062
regulation of cellular amine metabolic processGO:0033238200.062
ribonucleotide metabolic processGO:00092592910.061
cellular homeostasisGO:00197252400.061
regulation of cellular component biogenesisGO:00440871810.061
response to waterGO:000941510.061
microtubule based processGO:00070172360.061
regulation of antigen receptor mediated signaling pathwayGO:0050854290.061
regulation of antibacterial peptide biosynthetic processGO:000280810.060
cellular response to hormone stimulusGO:00328701500.059
Mouse
ribonucleoside triphosphate metabolic processGO:00091992200.059
glial cell apoptotic processGO:003434930.059
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.058
regulation of jnk cascadeGO:0046328620.058
lipid biosynthetic processGO:00086101790.058
cd4 positive alpha beta t cell activationGO:0035710450.058
release of cytochrome c from mitochondriaGO:0001836230.057
Mouse
positive regulation of t cell mediated immunityGO:0002711240.057
regulation of myeloid cell differentiationGO:0045637960.057
Human
ribose phosphate metabolic processGO:00196932910.057
positive regulation of antibacterial peptide biosynthetic processGO:000696310.057
digestive system developmentGO:00551232000.056
axonogenesisGO:00074092740.056
regulation of autophagyGO:0010506300.056
Mouse
negative regulation of cell activationGO:00508661110.056
Mouse
inflammatory responseGO:00069542440.055
Mouse
monocarboxylic acid transportGO:0015718440.055
positive regulation of antimicrobial peptide productionGO:000222510.055
embryonic epithelial tube formationGO:00018381300.055
compound eye developmentGO:004874910.054
regulation of protein complex assemblyGO:0043254830.054
nucleobase containing small molecule metabolic processGO:00550863520.054
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.054
positive regulation of lymphocyte mediated immunityGO:0002708620.053
positive regulation of erk1 and erk2 cascadeGO:0070374470.053
regulation of type i interferon mediated signaling pathwayGO:006033870.053
positive regulation of phosphatase activityGO:001092240.052
cation transportGO:00068123990.052
proteolysis involved in cellular protein catabolic processGO:00516031470.052
Human
positive regulation of protein phosphorylationGO:00019342420.052
rhythmic processGO:00485111740.052
cellular chemical homeostasisGO:00550822150.051
regulation of protein secretionGO:0050708820.051
Mouse
angiogenesisGO:00015252010.051
keratinocyte differentiationGO:0030216480.050
Mouse
regulation of t helper cell differentiationGO:0045622140.050
translationGO:0006412930.050
interleukin 6 productionGO:0032635580.050
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.049
negative regulation of lymphocyte apoptotic processGO:0070229240.049
protein deacetylationGO:0006476320.048
protein localization to organelleGO:00333651850.048
sequestering of metal ionGO:0051238190.048
negative regulation of cellular component organizationGO:00511291940.048
regulation of t helper 1 cell differentiationGO:004562570.048
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.048
ear developmentGO:00435832000.047
negative regulation of t cell proliferationGO:0042130380.047
Mouse
male gamete generationGO:00482322850.047
regulation of cellular response to stressGO:00801351590.047
regulation of t cell migrationGO:2000404120.047
organelle localizationGO:00516401790.046
regulation of protein maturationGO:1903317960.046
regulation of lymphocyte migrationGO:2000401140.046
dna catabolic process endonucleolyticGO:0000737150.046
Mouse
anion transmembrane transportGO:0098656710.045
type i interferon signaling pathwayGO:0060337100.045
peptidyl tyrosine modificationGO:00182121450.045
purine ribonucleoside metabolic processGO:00461282410.045
cellular amide metabolic processGO:0043603580.045
protein deacylationGO:0035601360.045
negative thymic t cell selectionGO:0045060120.045
positive regulation of protein oligomerizationGO:003246140.044
protein importGO:00170381010.044
positive regulation of antimicrobial humoral responseGO:000276020.044
regulation of organelle organizationGO:00330432890.044
membrane depolarizationGO:0051899640.044
Mouse
regulation of antimicrobial humoral responseGO:000275930.043
regulation of t cell differentiationGO:0045580830.043
endodermal cell fate specificationGO:000171440.043
humoral immune responseGO:0006959570.043
cytokine biosynthetic processGO:0042089680.043
positive regulation of cellular amine metabolic processGO:003324050.043
response to interleukin 1GO:0070555110.042
regulation of body fluid levelsGO:00508781620.042
mitotic cell cycleGO:00002781950.042
positive regulation of defense response to bacteriumGO:190042610.042
ribose phosphate biosynthetic processGO:0046390590.042
regulation of cell cycle processGO:00105641600.042
positive regulation of stress activated mapk cascadeGO:0032874480.041
stem cell differentiationGO:00488632680.041
muscle cell differentiationGO:00426922610.041
amide transportGO:00428861380.041
positive regulation of alpha beta t cell proliferationGO:0046641120.041
regulation of protein serine threonine kinase activityGO:00719001570.041
Mouse
antibacterial peptide biosynthetic processGO:000278020.040
wnt signaling pathwayGO:00160551880.040
regulation of antimicrobial peptide biosynthetic processGO:000280510.040
leukocyte activation involved in immune responseGO:00023661260.040
skin developmentGO:00435882200.040
Mouse
toll like receptor signaling pathwayGO:0002224380.040
organophosphate biosynthetic processGO:00904071220.040
regulation of protein targetingGO:1903533610.039
myeloid cell homeostasisGO:00022621140.039
respiratory system developmentGO:00605411900.039
nuclear transportGO:00511691390.039
cellular response to steroid hormone stimulusGO:0071383330.039
Mouse
regulation of stress activated mapk cascadeGO:0032872690.039
peptidyl serine phosphorylationGO:0018105740.039
branching morphogenesis of an epithelial tubeGO:00487541590.039
endomembrane system organizationGO:00102561470.039
negative regulation of defense responseGO:0031348770.038
antimicrobial peptide productionGO:000277520.038
epithelial cell proliferationGO:00506731740.038
response to starvationGO:0042594650.038
positive regulation of protein deacetylationGO:009031290.038
lung developmentGO:00303241640.038
nucleoside metabolic processGO:00091162460.038
cellular lipid metabolic processGO:00442553230.037
regulation of nucleocytoplasmic transportGO:0046822730.037
g protein coupled receptor signaling pathwayGO:00071862430.037
lipid transportGO:0006869980.037
negative regulation of cellular amino acid metabolic processGO:004576300.037
ribonucleoside catabolic processGO:00424542060.037
regulation of ion transmembrane transporter activityGO:0032412540.037
ribonucleotide catabolic processGO:00092612080.037
inflammatory response to antigenic stimulusGO:0002437300.036
nucleoside phosphate catabolic processGO:19012922220.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.036
defense response to gram negative bacteriumGO:0050829280.036
extracellular structure organizationGO:00430621480.036
regulation of leukocyte mediated immunityGO:00027031040.036
ubiquitin dependent protein catabolic processGO:00065111290.036
cellular metal ion homeostasisGO:00068751510.036
regulation of osteoblast differentiationGO:0045667670.036
dephosphorylationGO:00163111290.035
purine ribonucleotide metabolic processGO:00091502900.035
t cell activation involved in immune responseGO:0002286430.035
divalent inorganic cation homeostasisGO:00725071380.034
response to endoplasmic reticulum stressGO:0034976530.034
Mouse
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.034
anatomical structure homeostasisGO:00602491450.034
purine containing compound metabolic processGO:00725213110.034
positive regulation of cd4 positive alpha beta t cell differentiationGO:0043372140.033
purine nucleoside metabolic processGO:00422782410.033
vesicle organizationGO:0016050600.033
positive regulation of necroptotic processGO:006054510.033
purine nucleoside triphosphate metabolic processGO:00091442260.033
regulation of neuron differentiationGO:00456642810.032
purine containing compound catabolic processGO:00725232130.032
urogenital system developmentGO:00016552610.032
dna metabolic processGO:00062593030.032
Mouse
myeloid leukocyte differentiationGO:00025731190.032
carboxylic acid transportGO:00469421000.032
nuclear importGO:0051170950.032
glycerolipid biosynthetic processGO:0045017500.032
small molecule biosynthetic processGO:00442831320.032
cytokine secretionGO:0050663720.031
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.031
regulation of neuron deathGO:19012141340.031
Mouse
actin filament polymerizationGO:0030041440.031
regulation of interleukin 1 beta secretionGO:0050706150.030
Mouse
regulation of antimicrobial peptide productionGO:000278410.030
cardiac muscle cell contractionGO:008600370.030
positive regulation of interferon alpha productionGO:003272740.030

Casp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.152
disease of anatomical entityDOID:700.152
hypersensitivity reaction diseaseDOID:006005600.152
disease of cellular proliferationDOID:1456600.053
Human
cancerDOID:16200.042
Human
organ system cancerDOID:005068600.042
Human
disease by infectious agentDOID:005011700.031