Mus musculus

131 known processes

Pias4

protein inhibitor of activated STAT 4

(Aliases: PIASY,Piasg,Pias-gamma)

Pias4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic signaling pathwayGO:00971903060.168
regulation of apoptotic signaling pathwayGO:20012331970.155
intrinsic apoptotic signaling pathwayGO:00971931320.144
positive regulation of nervous system developmentGO:00519622210.106
cellular response to dna damage stimulusGO:00069742070.096
positive regulation of cell deathGO:00109422240.090
positive regulation of apoptotic signaling pathwayGO:2001235950.079
positive regulation of programmed cell deathGO:00430682180.079
muscle tissue developmentGO:00605373080.077
macromolecule catabolic processGO:00090572810.070
Mouse
cellular ketone metabolic processGO:0042180840.069
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.068
male gamete generationGO:00482322850.063
germ cell developmentGO:00072811850.061
positive regulation of cell developmentGO:00107202370.061
spermatogenesisGO:00072832840.059
regulation of cellular ketone metabolic processGO:0010565660.059
multicellular organism growthGO:00352641610.056
Worm
acylglycerol biosynthetic processGO:0046463180.055
urogenital system developmentGO:00016552610.055
striated muscle tissue developmentGO:00147062930.051
chromatin modificationGO:00165681870.049
peptidyl amino acid modificationGO:00181933360.048
chromatin organizationGO:00063252060.045
covalent chromatin modificationGO:00165691630.044
positive regulation of apoptotic processGO:00430652170.044
protein localization to organelleGO:00333651850.043
mitotic cell cycleGO:00002781950.043
Fly
cytoplasmic transportGO:00164822340.043
dna metabolic processGO:00062593030.042
Fly
actin cytoskeleton organizationGO:00300362200.041
regulation of cell cycleGO:00517262810.040
Fly
cellular amino acid metabolic processGO:00065201030.040
protein modification by small protein conjugationGO:00324461870.039
protein catabolic processGO:00301632210.038
Mouse
regulation of bindingGO:00510981110.038
homeostasis of number of cellsGO:00488722100.038
posttranscriptional regulation of gene expressionGO:00106081550.037
regulation of neuron differentiationGO:00456642810.036
negative regulation of cellular protein metabolic processGO:00322692470.036
gliogenesisGO:00420631410.036
protein ubiquitinationGO:00165671710.035
regulation of cell cycle processGO:00105641600.035
Fly
negative regulation of cell proliferationGO:00082852960.035
membrane organizationGO:00610242450.034
response to organonitrogen compoundGO:00102432460.034
regulation of plasma lipoprotein particle levelsGO:0097006230.033
histone modificationGO:00165701590.033
cellular macromolecule catabolic processGO:00442652060.031
Mouse
gene silencingGO:0016458380.031
cell fate commitmentGO:00451652100.031
development of primary sexual characteristicsGO:00451371430.030
Worm
compound eye developmentGO:004874910.030
Fly
stem cell differentiationGO:00488632680.030
mrna metabolic processGO:0016071840.029
rhythmic processGO:00485111740.029
nitrogen compound transportGO:00717052710.029
oocyte axis specificationGO:000730920.029
limb developmentGO:00601731660.028
regulation of cellular amino acid metabolic processGO:000652150.028
rna splicingGO:0008380540.028
spermatid differentiationGO:00485151150.028
protein maturationGO:00516041760.027
skeletal muscle organ developmentGO:00605381630.027
negative regulation of protein metabolic processGO:00512482820.027
regulation of cell morphogenesis involved in differentiationGO:00107691510.027
camera type eye developmentGO:00430102660.026
triglyceride biosynthetic processGO:0019432170.026
gland developmentGO:00487323300.026
rna processingGO:00063961050.026
carbohydrate metabolic processGO:00059752300.026
protein lipid complex subunit organizationGO:0071825120.026
protein acylationGO:0043543640.026
synaptic transmissionGO:00072683290.026
lipid biosynthetic processGO:00086101790.026
mrna processingGO:0006397630.026
negative regulation of dna replicationGO:000815640.025
myeloid cell differentiationGO:00300992330.025
renal system developmentGO:00720012250.025
intracellular protein transportGO:00068862040.025
limb morphogenesisGO:00351081490.025
sensory system developmentGO:004888030.025
protein methylationGO:0006479810.025
myeloid cell homeostasisGO:00022621140.024
negative regulation of triglyceride metabolic processGO:009020940.024
protein modification by small protein conjugation or removalGO:00706472070.024
glycerolipid biosynthetic processGO:0045017500.024
regulation of antimicrobial humoral responseGO:000275930.023
glycerolipid metabolic processGO:00464861220.023
protein processingGO:00164851630.023
cellular amine metabolic processGO:0044106440.023
peptidyl lysine modificationGO:0018205770.023
regulation of membrane potentialGO:00423911920.023
monocarboxylic acid metabolic processGO:00327871910.023
immune effector processGO:00022523210.022
cellular protein catabolic processGO:00442571550.022
Mouse
regulation of chromosome organizationGO:0033044830.022
retrograde transport endosome to golgiGO:004214720.022
rna interferenceGO:001624620.022
viral gene expressionGO:001908030.022
internal protein amino acid acetylationGO:0006475420.022
regulation of triglyceride biosynthetic processGO:0010866100.022
negative regulation of protein modification processGO:00314001630.021
regulation of transferase activityGO:00513382630.021
negative regulation of intracellular signal transductionGO:19025321670.021
regulation of striated muscle cell differentiationGO:0051153810.021
heterocycle catabolic processGO:00467002800.021
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.021
negative regulation of phosphorylationGO:00423261660.020
positive regulation of protein modification processGO:00314012990.020
Human
cell cycle checkpointGO:0000075470.020
Fly
regulation of cellular amine metabolic processGO:0033238200.020
asymmetric neuroblast divisionGO:005505910.020
guanosine containing compound catabolic processGO:19010691440.020
sensory perceptionGO:00076002450.020
rab protein signal transductionGO:003248210.020
reactive oxygen species metabolic processGO:0072593840.020
regulation of organelle organizationGO:00330432890.020
signal transduction by p53 class mediatorGO:0072331510.020
histone acetylationGO:0016573410.019
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.019
negative regulation of cellular amine metabolic processGO:003323910.019
nucleobase containing small molecule metabolic processGO:00550863520.019
amine metabolic processGO:0009308450.019
axonogenesisGO:00074092740.019
protein targetingGO:00066051430.019
negative regulation of protein phosphorylationGO:00019331260.019
skeletal muscle cell differentiationGO:0035914660.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
peptidyl lysine acetylationGO:0018394450.019
response to peptide hormoneGO:00434341270.019
oxidation reduction processGO:00551143420.019
forebrain developmentGO:00309003020.019
response to peptideGO:19016521360.019
locomotory behaviorGO:00076261950.019
antimicrobial peptide productionGO:000277520.018
spermatid developmentGO:00072861080.018
positive regulation of neuron differentiationGO:00456661410.018
regulation of homeostatic processGO:00328441820.018
oocyte constructionGO:000730820.018
cellular nitrogen compound catabolic processGO:00442702800.018
regulation of mitotic cell cycleGO:00073461260.018
Fly
muscle cell differentiationGO:00426922610.018
regulation of rna splicingGO:0043484370.018
maintenance of locationGO:0051235890.018
asymmetric stem cell divisionGO:009872230.018
macromolecule methylationGO:00434141200.018
regulation of cell activationGO:00508652890.018
internal peptidyl lysine acetylationGO:0018393420.018
myotube differentiationGO:00149021050.017
neutral lipid biosynthetic processGO:0046460180.017
appendage developmentGO:00487361660.017
regulation of translationGO:0006417710.017
cellular lipid metabolic processGO:00442553230.017
histone methylationGO:0016571710.017
cell growthGO:00160491300.017
negative regulation of molecular functionGO:00440922580.017
modification dependent macromolecule catabolic processGO:00436321330.017
Mouse
cellular homeostasisGO:00197252400.017
methylationGO:00322591340.017
cellular response to organonitrogen compoundGO:00714171450.017
organelle localizationGO:00516401790.017
epithelial cell proliferationGO:00506731740.017
endomembrane system organizationGO:00102561470.017
response to lipopolysaccharideGO:00324961280.017
regulation of neuron projection developmentGO:00109751690.017
organ growthGO:00352651170.017
appendage morphogenesisGO:00351071490.017
neural precursor cell proliferationGO:00613511210.017
histone lysine methylationGO:0034968500.016
regulation of cell cycle phase transitionGO:1901987770.016
Fly
leukocyte differentiationGO:00025213420.016
hormone secretionGO:00468791280.016
organonitrogen compound catabolic processGO:19015652640.016
small gtpase mediated signal transductionGO:0007264970.016
hematopoietic progenitor cell differentiationGO:00022441430.016
stem cell developmentGO:00488642190.016
neural tube developmentGO:00219151600.016
g1 s transition of mitotic cell cycleGO:0000082570.016
purine containing compound metabolic processGO:00725213110.016
regulation of cellular catabolic processGO:00313292420.016
Mouse
response to molecule of bacterial originGO:00022371430.016
meiotic cell cycle processGO:1903046770.016
neuron apoptotic processGO:00514021420.016
regulation of sequence specific dna binding transcription factor activityGO:00510901060.016
positive regulation of bindingGO:0051099490.016
regionalizationGO:00030023370.016
blastocyst developmentGO:0001824800.016
regulation of anatomical structure sizeGO:00900661780.015
ras protein signal transductionGO:0007265770.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
triglyceride metabolic processGO:0006641510.015
multi multicellular organism processGO:00447061090.015
meiosis iGO:0007127600.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
negative regulation of cell developmentGO:00107211690.015
regulation of cellular response to stressGO:00801351590.015
transmembrane transportGO:00550854120.015
response to acid chemicalGO:00011011110.015
peptidyl serine modificationGO:0018209830.015
female gamete generationGO:0007292740.015
translationGO:0006412930.015
regulation of secretion by cellGO:19035302490.015
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.015
carbohydrate homeostasisGO:00335001280.015
regulation of protein maturationGO:1903317960.015
regulation of cellular component sizeGO:00325351210.015
positive regulation of proteolysisGO:0045862850.015
Mouse
blood vessel morphogenesisGO:00485142850.015
cardiac muscle tissue developmentGO:00487381300.015
nucleotide metabolic processGO:00091173320.015
skeletal system developmentGO:00015013560.015
dna repairGO:00062811070.015
cell divisionGO:00513011200.015
proteasomal protein catabolic processGO:0010498980.015
Mouse
respiratory system developmentGO:00605411900.015
meiotic cell cycleGO:00513211220.015
neuroblast differentiationGO:001401620.015
neuron deathGO:00709971540.015
negative regulation of immune system processGO:00026832090.015
Zebrafish
ribonucleoside metabolic processGO:00091192450.014
acylglycerol metabolic processGO:0006639550.014
regulation of hydrolase activityGO:00513362460.014
rna splicing via transesterification reactionsGO:0000375430.014
inflammatory responseGO:00069542440.014
vesicle localizationGO:0051648860.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
Mouse
pharynx developmentGO:006046510.014
Worm
regulation of proteolysisGO:00301621640.014
Mouse
regulation of cellular component biogenesisGO:00440871810.014
zygotic determination of anterior posterior axis embryoGO:000735430.014
regulation of fibroblast proliferationGO:0048145340.014
purine ribonucleoside metabolic processGO:00461282410.014
developmental maturationGO:00217001930.014
regulation of multi organism processGO:00439001110.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.014
purine containing compound catabolic processGO:00725232130.014
microtubule based processGO:00070172360.014
purine ribonucleotide catabolic processGO:00091542080.014
histone h3 acetylationGO:0043966140.014
transmission of nerve impulseGO:0019226760.014
wnt signaling pathwayGO:00160551880.014
signal transduction involved in mitotic dna damage checkpointGO:190240230.014
lymphocyte differentiationGO:00300982420.014
lateral inhibitionGO:004633110.014
purine nucleotide catabolic processGO:00061952110.014
viral transcriptionGO:001908330.014
regulation of mrna processingGO:0050684410.013
cellular response to peptideGO:1901653920.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
carboxylic acid biosynthetic processGO:0046394860.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
meiotic nuclear divisionGO:00071261150.013
ribonucleoside catabolic processGO:00424542060.013
endocytosisGO:00068971680.013
carbohydrate derivative catabolic processGO:19011362310.013
response to oxidative stressGO:00069791230.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
epithelial tube formationGO:00721751300.013
negative regulation of cell cycleGO:00457861230.013
Fly
neutral lipid metabolic processGO:0006638570.013
protein localization to nucleusGO:00345041210.013
neural tube formationGO:00018411080.013
regulation of secretionGO:00510462740.013
nucleoside triphosphate metabolic processGO:00091412300.013
positive regulation of cellular catabolic processGO:00313311480.013
Mouse
reactive oxygen species biosynthetic processGO:190340980.013
response to growth factorGO:00708481980.013
gtp metabolic processGO:00460391440.013
small molecule biosynthetic processGO:00442831320.013
metencephalon developmentGO:0022037890.013
telencephalon developmentGO:00215371860.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
purine nucleotide metabolic processGO:00061633020.013
aromatic compound catabolic processGO:00194392860.013
hindbrain developmentGO:00309021280.013
establishment of protein localization to organelleGO:00725941180.013
multicellular organismal signalingGO:0035637910.013
purine nucleoside metabolic processGO:00422782410.013
ribose phosphate metabolic processGO:00196932910.013
gtp catabolic processGO:00061841430.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
negative regulation of neuron differentiationGO:00456651010.013
phagocytosisGO:0006909660.013
negative regulation of proteolysisGO:0045861740.013
cellular response to lipidGO:00713961450.013
gonad developmentGO:00084061410.013
Worm
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.013
oocyte anterior posterior axis specificationGO:000731420.013
positive regulation of cellular amine metabolic processGO:003324050.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
Mouse
regulation of actin filament based processGO:0032970990.012
negative regulation of protein processingGO:0010955790.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
positive regulation of organelle organizationGO:00106381280.012
positive regulation of transferase activityGO:00513471670.012
neuronal action potentialGO:0019228540.012
regulation of protein catabolic processGO:00421761080.012
Mouse
regulation of mapk cascadeGO:00434082480.012
primary neural tube formationGO:0014020950.012
regulation of mrna splicing via spliceosomeGO:0048024320.012
response to inorganic substanceGO:0010035960.012
circadian rhythmGO:00076231140.012
exocytosisGO:00068871210.012
negative regulation of cellular component organizationGO:00511291940.012
organic acid biosynthetic processGO:0016053860.012
negative regulation of phosphate metabolic processGO:00459361840.012
protein alkylationGO:0008213810.012
glycosyl compound catabolic processGO:19016582060.012
oogenesisGO:0048477560.012
cardiocyte differentiationGO:0035051870.012
response to organic cyclic compoundGO:00140701980.012
regulation of lipid biosynthetic processGO:0046890540.012
segmentationGO:0035282930.012
protein autophosphorylationGO:0046777610.012
b cell activationGO:00421131610.012
engulfment of apoptotic cellGO:004365230.012
myeloid leukocyte differentiationGO:00025731190.012
male courtship behaviorGO:000804920.012
male meiosis iGO:0007141160.012
negative regulation of growthGO:0045926990.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
epithelial tube morphogenesisGO:00605623030.012
negative regulation of protein maturationGO:1903318790.012
cation homeostasisGO:00550802120.011
regulation of protein processingGO:0070613960.011
nucleocytoplasmic transportGO:00069131390.011
t cell activationGO:00421102890.011
cell type specific apoptotic processGO:00972852680.011
positive regulation of hydrolase activityGO:00513451480.011
purine ribonucleoside catabolic processGO:00461302050.011
cellular response to lipopolysaccharideGO:0071222770.011
negative regulation of cell cycle processGO:0010948690.011
Fly
fertilizationGO:00095661270.011
fibroblast proliferationGO:0048144350.011
cytokine productionGO:00018163190.011
Zebrafish
lens development in camera type eyeGO:0002088620.011
organophosphate catabolic processGO:00464342320.011
response to light stimulusGO:00094161350.011
regulation of lipid metabolic processGO:00192161180.011
regulation of leukocyte differentiationGO:19021051590.011
stem cell maintenanceGO:00198271300.011
regulation of neuron deathGO:19012141340.011
defecationGO:003042110.011
spleen developmentGO:0048536390.011
regulation of chromatin organizationGO:1902275570.011
regulation of cell projection organizationGO:00313442060.011
organonitrogen compound biosynthetic processGO:19015661920.011
positive regulation of cellular component biogenesisGO:0044089940.011
response to reactive oxygen speciesGO:0000302560.011
dendrite developmentGO:00163581150.011
regulation of myeloid cell differentiationGO:0045637960.011
glycoprotein metabolic processGO:00091001160.011
embryonic limb morphogenesisGO:00303261260.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
regulation of system processGO:00440572000.011
anion transportGO:00068201770.011
maternal determination of anterior posterior axis embryoGO:000835820.011
response to radiationGO:00093141650.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
organelle fissionGO:00482851700.011
regulation of viral transcriptionGO:004678230.011
regulation of neuron apoptotic processGO:00435231220.011
learning or memoryGO:00076111480.011
cell cycle g1 s phase transitionGO:0044843570.011
development of primary male sexual characteristicsGO:0046546880.011
symbiosis encompassing mutualism through parasitismGO:0044403830.010
cellular response to hormone stimulusGO:00328701500.010
organic cyclic compound catabolic processGO:19013612950.010
regulation of antimicrobial peptide productionGO:000278410.010
regulation of mrna metabolic processGO:1903311430.010
autophagyGO:0006914450.010
regulation of protein sumoylationGO:003323340.010
Human
regulation of protein bindingGO:0043393600.010
sensory perception of mechanical stimulusGO:00509541070.010
chemotaxisGO:00069352470.010
cellular component assembly involved in morphogenesisGO:00109271390.010
positive regulation of protein kinase activityGO:00458601440.010
actin filament organizationGO:00070151130.010
regulation of lymphocyte differentiationGO:00456191070.010
nucleoside phosphate catabolic processGO:19012922220.010
negative regulation of phosphorus metabolic processGO:00105631840.010
vesicle organizationGO:0016050600.010
notch signaling pathwayGO:0007219710.010
male sex differentiationGO:00466611090.010
actin polymerization or depolymerizationGO:0008154540.010

Pias4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.019
neuromuscular diseaseDOID:44000.019
neuropathyDOID:87000.019
charcot marie tooth diseaseDOID:1059500.019
organ system cancerDOID:005068600.015
immune system diseaseDOID:291400.014
muscular diseaseDOID:008000000.013
musculoskeletal system diseaseDOID:1700.013
hematopoietic system diseaseDOID:7400.010
muscle tissue diseaseDOID:6600.010
myopathyDOID:42300.010