| protein refolding | GO:0042026 | 1 | 0.998 | |
| dna metabolic process | GO:0006259 | 303 | 0.747 | Rat |
| organelle assembly | GO:0070925 | 177 | 0.697 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.663 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.559 | |
| microtubule based process | GO:0007017 | 236 | 0.554 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.505 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.477 | |
| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.432 | |
| toxin transport | GO:1901998 | 38 | 0.424 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.341 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.318 | |
| fertilization | GO:0009566 | 127 | 0.273 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.271 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.268 | |
| protein complex disassembly | GO:0043241 | 40 | 0.263 | |
| sperm egg recognition | GO:0035036 | 37 | 0.250 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.248 | |
| gonad development | GO:0008406 | 141 | 0.245 | |
| protein neddylation | GO:0045116 | 1 | 0.231 | |
| protein folding | GO:0006457 | 28 | 0.206 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 2 | 0.204 | |
| protein targeting to mitochondrion | GO:0006626 | 6 | 0.200 | |
| organelle disassembly | GO:1903008 | 2 | 0.199 | |
| chaperone mediated protein folding | GO:0061077 | 10 | 0.192 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.192 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.174 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.168 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.164 | |
| single fertilization | GO:0007338 | 82 | 0.151 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 10 | 0.141 | |
| male gamete generation | GO:0048232 | 285 | 0.139 | |
| cell recognition | GO:0008037 | 83 | 0.137 | |
| chromatin modification | GO:0016568 | 187 | 0.133 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.118 | |
| genitalia development | GO:0048806 | 37 | 0.115 | |
| protein catabolic process | GO:0030163 | 221 | 0.114 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.113 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.105 | |
| detection of stimulus | GO:0051606 | 84 | 0.104 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.103 | |
| actomyosin structure organization | GO:0031032 | 56 | 0.101 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.100 | |
| protein deubiquitination | GO:0016579 | 19 | 0.100 | |
| regulation of transposition | GO:0010528 | 2 | 0.091 | |
| response to heat | GO:0009408 | 27 | 0.090 | |
| de novo protein folding | GO:0006458 | 9 | 0.089 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.087 | |
| rna transport | GO:0050658 | 18 | 0.086 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.085 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.085 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.084 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.082 | |
| centrosome cycle | GO:0007098 | 23 | 0.082 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.079 | |
| regulation of cell division | GO:0051302 | 76 | 0.075 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.075 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.073 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.072 | |
| dendrite development | GO:0016358 | 115 | 0.070 | |
| protein localization to mitochondrion | GO:0070585 | 15 | 0.069 | |
| rna interference | GO:0016246 | 2 | 0.068 | |
| myosin filament organization | GO:0031033 | 3 | 0.065 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.064 | |
| rna dependent dna replication | GO:0006278 | 3 | 0.062 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.062 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.062 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.061 | |
| ribonucleoprotein complex localization | GO:0071166 | 1 | 0.058 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.057 | |
| pole plasm assembly | GO:0007315 | 2 | 0.055 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.051 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.051 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.049 | |
| lung development | GO:0030324 | 164 | 0.046 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.046 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.046 | |
| endocytosis | GO:0006897 | 168 | 0.045 | |
| rrna containing ribonucleoprotein complex export from nucleus | GO:0071428 | 1 | 0.045 | |
| binding of sperm to zona pellucida | GO:0007339 | 34 | 0.044 | |
| positive regulation of striated muscle contraction | GO:0045989 | 3 | 0.044 | |
| centriole assembly | GO:0098534 | 6 | 0.044 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.043 | |
| chromatin organization | GO:0006325 | 206 | 0.043 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.043 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.043 | |
| cell cell recognition | GO:0009988 | 44 | 0.040 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.039 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.039 | |
| macromolecular complex disassembly | GO:0032984 | 43 | 0.039 | |
| gene silencing | GO:0016458 | 38 | 0.038 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.038 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.037 | |
| polyamine biosynthetic process | GO:0006596 | 2 | 0.037 | |
| histone modification | GO:0016570 | 159 | 0.037 | |
| nuclear division | GO:0000280 | 158 | 0.037 | |
| oocyte construction | GO:0007308 | 2 | 0.037 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 37 | 0.037 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.037 | |
| ribosomal subunit export from nucleus | GO:0000054 | 1 | 0.036 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.036 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.036 | |
| regulation of centrosome cycle | GO:0046605 | 10 | 0.036 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.035 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.034 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.034 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.034 | |
| protein ubiquitination | GO:0016567 | 171 | 0.034 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.034 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.032 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.032 | |
| rna processing | GO:0006396 | 105 | 0.032 | |
| respiratory system development | GO:0060541 | 190 | 0.032 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.032 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.031 | |
| determination of adult lifespan | GO:0008340 | 11 | 0.030 | |
| multicellular organismal aging | GO:0010259 | 24 | 0.029 | |
| proteasome assembly | GO:0043248 | 1 | 0.028 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.028 | |
| regulation of cell size | GO:0008361 | 72 | 0.028 | |
| cognition | GO:0050890 | 149 | 0.027 | |
| mitochondrion organization | GO:0007005 | 134 | 0.027 | |
| germ cell development | GO:0007281 | 185 | 0.027 | |
| mapk cascade | GO:0000165 | 281 | 0.027 | |
| female gamete generation | GO:0007292 | 74 | 0.027 | |
| spermatogenesis | GO:0007283 | 284 | 0.026 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.026 | |
| learning or memory | GO:0007611 | 148 | 0.026 | |
| positive regulation of lamellipodium organization | GO:1902745 | 3 | 0.026 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.025 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.025 | |
| telencephalon development | GO:0021537 | 186 | 0.024 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.024 | |
| response to light stimulus | GO:0009416 | 135 | 0.024 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.024 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.024 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.023 | |
| stress granule disassembly | GO:0035617 | 2 | 0.023 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.023 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.023 | |
| mitotic spindle organization | GO:0007052 | 10 | 0.023 | |
| pallium development | GO:0021543 | 120 | 0.023 | |
| regulation of microtubule based process | GO:0032886 | 52 | 0.023 | |
| mrna catabolic process | GO:0006402 | 22 | 0.023 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.022 | |
| regulation of protein transport | GO:0051223 | 163 | 0.022 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.021 | Rat |
| amine metabolic process | GO:0009308 | 45 | 0.021 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.021 | |
| organelle localization | GO:0051640 | 179 | 0.021 | |
| negative regulation of transposition | GO:0010529 | 2 | 0.021 | |
| histone acetylation | GO:0016573 | 41 | 0.021 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.021 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.020 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.020 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.020 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.020 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.020 | |
| neuron death | GO:0070997 | 154 | 0.020 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.019 | |
| protein transmembrane transport | GO:0071806 | 8 | 0.019 | |
| nucleic acid transport | GO:0050657 | 18 | 0.019 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 52 | 0.019 | |
| cellularization | GO:0007349 | 1 | 0.019 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.019 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.019 | |
| regulation of ion transport | GO:0043269 | 215 | 0.019 | |
| negative regulation of cell morphogenesis involved in differentiation | GO:0010771 | 48 | 0.019 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.019 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.019 | |
| negative regulation of protein ubiquitination | GO:0031397 | 19 | 0.019 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.018 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.018 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.018 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.018 | |
| negative regulation of neuron projection development | GO:0010977 | 50 | 0.018 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.018 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.018 | |
| mitochondrial transport | GO:0006839 | 36 | 0.018 | |
| muscle system process | GO:0003012 | 141 | 0.018 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.018 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.017 | |
| heart process | GO:0003015 | 94 | 0.017 | |
| vesicle uncoating | GO:0072319 | 4 | 0.017 | |
| centrosome organization | GO:0051297 | 26 | 0.017 | |
| cell maturation | GO:0048469 | 127 | 0.017 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.017 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.017 | |
| nuclear transport | GO:0051169 | 139 | 0.017 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.017 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.016 | |
| negative regulation of cell motility | GO:2000146 | 61 | 0.016 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.016 | |
| transmembrane transport | GO:0055085 | 412 | 0.016 | |
| intracellular protein transport | GO:0006886 | 204 | 0.016 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.016 | |
| synaptic transmission | GO:0007268 | 329 | 0.016 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.016 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.016 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.016 | |
| fungiform papilla morphogenesis | GO:0061197 | 5 | 0.016 | |
| response to radiation | GO:0009314 | 165 | 0.016 | |
| cellular protein complex disassembly | GO:0043624 | 36 | 0.016 | |
| negative regulation of protein modification by small protein conjugation or removal | GO:1903321 | 20 | 0.015 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.015 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.015 | |
| cellular response to heat | GO:0034605 | 15 | 0.015 | |
| protein maturation | GO:0051604 | 176 | 0.015 | |
| forebrain development | GO:0030900 | 302 | 0.014 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.014 | |
| regulation of dna templated transcription elongation | GO:0032784 | 10 | 0.014 | |
| regulation of binding | GO:0051098 | 111 | 0.014 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.014 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.014 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.014 | |
| organelle fission | GO:0048285 | 170 | 0.014 | |
| respiratory tube development | GO:0030323 | 167 | 0.014 | |
| centrosome separation | GO:0051299 | 4 | 0.014 | |
| regulation of protein localization | GO:0032880 | 231 | 0.014 | |
| neuron migration | GO:0001764 | 122 | 0.014 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.014 | |
| dna replication | GO:0006260 | 52 | 0.014 | Rat |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.013 | |
| muscle contraction | GO:0006936 | 101 | 0.013 | |
| protein import into nucleus | GO:0006606 | 95 | 0.013 | |
| nucleus localization | GO:0051647 | 20 | 0.013 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.013 | |
| developmental maturation | GO:0021700 | 193 | 0.013 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.013 | |
| forebrain morphogenesis | GO:0048853 | 17 | 0.013 | |
| ossification | GO:0001503 | 216 | 0.013 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.013 | |
| spindle organization | GO:0007051 | 28 | 0.013 | |
| blood circulation | GO:0008015 | 195 | 0.013 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.013 | |
| gastrin induced gastric acid secretion | GO:0001698 | 1 | 0.013 | |
| negative regulation of neuron differentiation | GO:0045665 | 101 | 0.013 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.013 | |
| regulation of ubiquitin protein ligase activity involved in mitotic cell cycle | GO:0051439 | 1 | 0.013 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.013 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.012 | |
| negative regulation of cell projection organization | GO:0031345 | 56 | 0.012 | |
| oocyte axis specification | GO:0007309 | 2 | 0.012 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.012 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.012 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.012 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.012 | |
| regulation of translational initiation | GO:0006446 | 15 | 0.012 | |
| positive regulation of gene expression epigenetic | GO:0045815 | 4 | 0.012 | |
| muscle tissue development | GO:0060537 | 308 | 0.012 | Rat |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.012 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| sensory perception of pain | GO:0019233 | 47 | 0.011 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 41 | 0.011 | |
| sensory perception | GO:0007600 | 245 | 0.011 | |
| regulation of dna templated transcription initiation | GO:2000142 | 7 | 0.011 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.011 | |
| protein depolymerization | GO:0051261 | 34 | 0.011 | |
| regulation of system process | GO:0044057 | 200 | 0.011 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.011 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.011 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.011 | |
| polyamine transport | GO:0015846 | 5 | 0.011 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.011 | |
| regulation of protein export from nucleus | GO:0046825 | 11 | 0.011 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.011 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.011 | |
| lateral ventricle development | GO:0021670 | 11 | 0.010 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.010 | |
| protein polymerization | GO:0051258 | 57 | 0.010 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.010 | |
