Mus musculus

194 known processes

Madd

MAP-kinase activating death domain

(Aliases: IG20,9630059K23Rik)

Madd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide catabolic processGO:00091662170.083
purine ribonucleoside triphosphate metabolic processGO:00092052200.082
nucleoside phosphate catabolic processGO:19012922220.082
small gtpase mediated signal transductionGO:0007264970.074
Human
regulation of cellular ketone metabolic processGO:0010565660.073
cellular nitrogen compound catabolic processGO:00442702800.071
purine nucleoside catabolic processGO:00061522050.071
ribonucleoside metabolic processGO:00091192450.069
amine metabolic processGO:0009308450.067
nucleotide metabolic processGO:00091173320.066
regulation of cellular amine metabolic processGO:0033238200.065
nucleoside triphosphate catabolic processGO:00091432050.065
carbohydrate derivative catabolic processGO:19011362310.064
ribonucleotide catabolic processGO:00092612080.064
nucleoside catabolic processGO:00091642060.064
regulation of cellular amino acid metabolic processGO:000652150.062
purine ribonucleoside metabolic processGO:00461282410.062
glycosyl compound metabolic processGO:19016572460.061
nucleobase containing small molecule metabolic processGO:00550863520.060
purine ribonucleoside catabolic processGO:00461302050.059
ribose phosphate metabolic processGO:00196932910.058
organic cyclic compound catabolic processGO:19013612950.055
cellular ketone metabolic processGO:0042180840.054
cellular amine metabolic processGO:0044106440.054
cellular amino acid metabolic processGO:00065201030.054
purine ribonucleoside triphosphate catabolic processGO:00092071990.053
glycosyl compound catabolic processGO:19016582060.053
nucleoside triphosphate metabolic processGO:00091412300.052
protein catabolic processGO:00301632210.052
Worm
nucleoside metabolic processGO:00091162460.052
ribonucleoside triphosphate catabolic processGO:00092031990.052
heterocycle catabolic processGO:00467002800.051
ras protein signal transductionGO:0007265770.050
Human
purine containing compound metabolic processGO:00725213110.049
aromatic compound catabolic processGO:00194392860.049
purine ribonucleotide metabolic processGO:00091502900.049
spermatogenesisGO:00072832840.048
Mouse
ribonucleotide metabolic processGO:00092592910.048
membrane organizationGO:00610242450.046
peptidyl amino acid modificationGO:00181933360.046
purine ribonucleotide catabolic processGO:00091542080.045
nucleoside phosphate metabolic processGO:00067533380.045
organophosphate catabolic processGO:00464342320.043
ribonucleoside catabolic processGO:00424542060.042
ion transmembrane transportGO:00342203610.042
purine nucleoside triphosphate catabolic processGO:00091462030.042
purine nucleoside triphosphate metabolic processGO:00091442260.041
purine nucleotide metabolic processGO:00061633020.040
microtubule based movementGO:0007018840.039
regulation of vesicle mediated transportGO:00606271390.039
ribonucleoside triphosphate metabolic processGO:00091992200.039
purine containing compound catabolic processGO:00725232130.038
regulation of nucleotide metabolic processGO:00061401690.038
purine nucleotide catabolic processGO:00061952110.038
transmembrane transportGO:00550854120.038
cellular lipid metabolic processGO:00442553230.038
cation transportGO:00068123990.037
Worm
regulation of hydrolase activityGO:00513362460.037
regulation of kinase activityGO:00435492490.036
macromolecule catabolic processGO:00090572810.035
Worm
organonitrogen compound catabolic processGO:19015652640.035
protein modification by small protein conjugation or removalGO:00706472070.035
guanosine containing compound metabolic processGO:19010681440.034
gtp catabolic processGO:00061841430.034
inorganic cation transmembrane transportGO:00986622070.034
negative regulation of protein metabolic processGO:00512482820.034
regulation of synaptic growth at neuromuscular junctionGO:000858240.033
negative regulation of cellular protein metabolic processGO:00322692470.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
regulation of purine nucleotide metabolic processGO:19005421690.032
axonogenesisGO:00074092740.032
histone modificationGO:00165701590.032
regulation of gtp catabolic processGO:00331241130.031
dna metabolic processGO:00062593030.031
regulation of membrane potentialGO:00423911920.031
positive regulation of cellular amine metabolic processGO:003324050.031
negative regulation of molecular functionGO:00440922580.030
cation transmembrane transportGO:00986552660.030
germ cell developmentGO:00072811850.030
regulation of secretionGO:00510462740.029
Worm
forebrain developmentGO:00309003020.029
myeloid cell differentiationGO:00300992330.029
regulation of ras protein signal transductionGO:00465781140.029
regulation of neuron differentiationGO:00456642810.028
cell type specific apoptotic processGO:00972852680.028
protein maturationGO:00516041760.028
leukocyte differentiationGO:00025213420.028
guanosine containing compound catabolic processGO:19010691440.028
regulation of secretion by cellGO:19035302490.028
Worm
synaptic transmissionGO:00072683290.027
Worm
actin cytoskeleton organizationGO:00300362200.027
gtp metabolic processGO:00460391440.027
sensory perceptionGO:00076002450.027
gland developmentGO:00487323300.027
negative regulation of cellular amine metabolic processGO:003323910.026
microtubule based processGO:00070172360.026
purine nucleoside metabolic processGO:00422782410.026
positive regulation of purine nucleotide metabolic processGO:19005441140.026
cytoplasmic transportGO:00164822340.026
organelle localizationGO:00516401790.026
actin polymerization or depolymerizationGO:0008154540.026
chromatin organizationGO:00063252060.026
endomembrane system organizationGO:00102561470.025
regulation of organelle organizationGO:00330432890.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
compound eye developmentGO:004874910.025
regulation of anatomical structure sizeGO:00900661780.024
regulation of cellular catabolic processGO:00313292420.024
rho protein signal transductionGO:0007266320.024
cilium morphogenesisGO:00602711020.024
negative regulation of protein phosphorylationGO:00019331260.024
immune effector processGO:00022523210.024
regulation of transferase activityGO:00513382630.024
protein modification by small protein conjugationGO:00324461870.024
intracellular protein transportGO:00068862040.024
organelle assemblyGO:00709251770.024
endocytosisGO:00068971680.024
regulation of neuron projection developmentGO:00109751690.024
cellular component assembly involved in morphogenesisGO:00109271390.023
positive regulation of nervous system developmentGO:00519622210.023
regulation of cell projection organizationGO:00313442060.023
regulation of cellular component biogenesisGO:00440871810.023
nitrogen compound transportGO:00717052710.023
Worm
synapse organizationGO:00508081250.023
inorganic ion transmembrane transportGO:00986602340.022
regulation of nucleotide catabolic processGO:00308111220.022
male gamete generationGO:00482322850.022
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.022
positive regulation of protein phosphorylationGO:00019342420.022
dendrite developmentGO:00163581150.022
protein localization to organelleGO:00333651850.021
organelle fissionGO:00482851700.021
cellular macromolecule catabolic processGO:00442652060.021
regulation of homeostatic processGO:00328441820.021
response to organic cyclic compoundGO:00140701980.021
protein targetingGO:00066051430.021
monocarboxylic acid metabolic processGO:00327871910.021
negative regulation of cell proliferationGO:00082852960.021
asymmetric stem cell divisionGO:009872230.021
divalent inorganic cation transportGO:00725111780.021
oxidation reduction processGO:00551143420.020
multicellular organismal signalingGO:0035637910.020
positive regulation of neuron differentiationGO:00456661410.020
organic hydroxy compound metabolic processGO:19016152030.020
cellular protein complex assemblyGO:00436231160.020
negative regulation of cell developmentGO:00107211690.020
protein processingGO:00164851630.019
response to organonitrogen compoundGO:00102432460.019
rap protein signal transductionGO:003248630.019
actin filament polymerizationGO:0030041440.019
negative regulation of cellular component organizationGO:00511291940.019
negative regulation of nervous system developmentGO:00519611560.019
cellular protein catabolic processGO:00442571550.019
glycerolipid metabolic processGO:00464861220.019
nuclear divisionGO:00002801580.019
regulation of defense responseGO:00313472330.019
establishment of vesicle localizationGO:0051650810.019
regulation of cell cycleGO:00517262810.019
macromolecule methylationGO:00434141200.019
regulation of lymphocyte activationGO:00512492400.019
establishment of organelle localizationGO:00516561220.019
positive regulation of purine nucleotide catabolic processGO:0033123880.019
regulation of purine nucleotide catabolic processGO:00331211220.018
mitochondrion organizationGO:00070051340.018
homeostasis of number of cellsGO:00488722100.018
blood vessel morphogenesisGO:00485142850.018
t cell activationGO:00421102890.018
regulation of protein kinase activityGO:00458592320.018
chromatin modificationGO:00165681870.018
negative regulation of phosphorus metabolic processGO:00105631840.018
positive regulation of nucleoside metabolic processGO:0045979910.018
cell growthGO:00160491300.018
methylationGO:00322591340.018
negative regulation of phosphate metabolic processGO:00459361840.018
multicellular organism growthGO:00352641610.018
positive regulation of protein modification processGO:00314012990.018
regulation of protein localizationGO:00328802310.018
fertilizationGO:00095661270.018
spermatid differentiationGO:00485151150.018
regulation of ion transportGO:00432692150.017
Worm
response to light stimulusGO:00094161350.017
response to radiationGO:00093141650.017
response to insulinGO:00328681000.017
protein polymerizationGO:0051258570.017
amide transportGO:00428861380.017
cellular response to hormone stimulusGO:00328701500.017
cellular response to lipidGO:00713961450.017
cellularizationGO:000734910.017
muscle tissue developmentGO:00605373080.017
positive regulation of hydrolase activityGO:00513451480.017
mapk cascadeGO:00001652810.017
regulation of ion transmembrane transportGO:00347651190.017
cellular homeostasisGO:00197252400.017
protein ubiquitinationGO:00165671710.017
hematopoietic progenitor cell differentiationGO:00022441430.017
phospholipid metabolic processGO:0006644870.017
regulation of cytoskeleton organizationGO:00514931220.016
cellular response to organonitrogen compoundGO:00714171450.016
reactive oxygen species metabolic processGO:0072593840.016
transmission of nerve impulseGO:0019226760.016
myosin filament assemblyGO:003103420.016
retrograde transport endosome to golgiGO:004214720.016
multicellular organismal homeostasisGO:00488711640.016
positive regulation of cell developmentGO:00107202370.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
chemotaxisGO:00069352470.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of cell migrationGO:00303342190.016
multi multicellular organism processGO:00447061090.016
Worm
cellular ion homeostasisGO:00068731650.016
regulation of reactive oxygen species metabolic processGO:2000377400.016
sensory organ morphogenesisGO:00905962420.016
negative regulation of synapse assemblyGO:005196430.016
regulation of feeding behaviorGO:006025930.015
regulation of transmembrane transportGO:00347621280.015
regulation of neurotransmitter levelsGO:0001505870.015
Worm
lipid homeostasisGO:0055088630.015
anatomical structure homeostasisGO:00602491450.015
synaptic vesicle localizationGO:0097479590.015
learning or memoryGO:00076111480.015
regulation of cell activationGO:00508652890.015
cellular chemical homeostasisGO:00550822150.015
lipid biosynthetic processGO:00086101790.015
cellular response to biotic stimulusGO:0071216920.015
neuron deathGO:00709971540.015
cell activation involved in immune responseGO:00022631260.015
positive regulation of cellular catabolic processGO:00313311480.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
response to growth factorGO:00708481980.015
cell adhesionGO:00071553290.015
protein autophosphorylationGO:0046777610.015
regulation of lipid metabolic processGO:00192161180.015
axon guidanceGO:00074111410.015
protein alkylationGO:0008213810.015
cytokine productionGO:00018163190.015
striated muscle myosin thick filament assemblyGO:007168810.014
positive regulation of creb transcription factor activityGO:003279340.014
activation of immune responseGO:00022531380.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
innate immune responseGO:00450871570.014
anion transportGO:00068201770.014
oocyte axis specificationGO:000730920.014
regulation of cell motilityGO:20001452360.014
myosin filament organizationGO:003103330.014
positive regulation of cellular component biogenesisGO:0044089940.014
microtubule cytoskeleton organizationGO:00002261570.014
negative regulation of intracellular signal transductionGO:19025321670.014
response to peptideGO:19016521360.014
cellular response to dna damage stimulusGO:00069742070.014
covalent chromatin modificationGO:00165691630.014
small molecule biosynthetic processGO:00442831320.014
organophosphate biosynthetic processGO:00904071220.014
protein methylationGO:0006479810.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
skeletal system developmentGO:00015013560.014
exocytosisGO:00068871210.014
calcium ion transmembrane transportGO:0070588850.014
cellular metal ion homeostasisGO:00068751510.014
carbohydrate derivative biosynthetic processGO:19011371830.014
regulation of t cell activationGO:00508631700.014
regulation of actin filament based processGO:0032970990.014
muscle contractionGO:00069361010.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
placenta developmentGO:00018901400.014
positive regulation of cell deathGO:00109422240.013
locomotory behaviorGO:00076261950.013
regulation of hormone levelsGO:00108172110.013
peptide secretionGO:00027901140.013
positive regulation of nucleotide metabolic processGO:00459811140.013
negative regulation of protein modification processGO:00314001630.013
nucleoside monophosphate metabolic processGO:0009123850.013
atp metabolic processGO:0046034750.013
embryonic organ morphogenesisGO:00485622760.013
glycerophospholipid metabolic processGO:0006650710.013
sensory perception of soundGO:0007605970.013
histone methylationGO:0016571710.013
lateral inhibitionGO:004633110.013
cytokine mediated signaling pathwayGO:00192211150.013
maintenance of locationGO:0051235890.013
lymphocyte differentiationGO:00300982420.013
divalent metal ion transportGO:00708381720.013
actin filament organizationGO:00070151130.013
cilium assemblyGO:0042384810.013
lipid modificationGO:0030258650.013
membrane tubulationGO:009732040.013
developmental cell growthGO:0048588840.013
response to peptide hormoneGO:00434341270.013
regulation of rho gtpase activityGO:0032319580.013
peptide hormone secretionGO:00300721090.013
regulation of endocytosisGO:0030100690.013
negative regulation of phosphorylationGO:00423261660.013
regulation of establishment of protein localizationGO:00702011810.013
positive regulation of mapk cascadeGO:00434101700.013
carbohydrate metabolic processGO:00059752300.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
regulation of proteolysisGO:00301621640.013
positive regulation of gtpase activityGO:0043547850.013
oocyte constructionGO:000730820.013
regulation of cytokine productionGO:00018172660.013
regulation of nucleoside metabolic processGO:00091181300.013
skin developmentGO:00435882200.013
positive regulation of programmed cell deathGO:00430682180.013
vesicle localizationGO:0051648860.013
striated muscle tissue developmentGO:00147062930.012
modification dependent protein catabolic processGO:00199411330.012
camera type eye developmentGO:00430102660.012
positive regulation of gtp catabolic processGO:0033126850.012
regulation of cellular component sizeGO:00325351210.012
regulation of body fluid levelsGO:00508781620.012
spermatid developmentGO:00072861080.012
carbohydrate homeostasisGO:00335001280.012
neuron apoptotic processGO:00514021420.012
skeletal muscle organ developmentGO:00605381630.012
positive regulation of growthGO:00459271040.012
microtubule based transportGO:0010970500.012
protein localization to membraneGO:00726571080.012
regionalizationGO:00030023370.012
nuclear transportGO:00511691390.012
protein localization to plasma membraneGO:0072659570.012
response to molecule of bacterial originGO:00022371430.012
adult behaviorGO:00305341350.012
neurotransmitter transportGO:0006836760.012
Worm
engulfment of apoptotic cellGO:004365230.012
cellular response to molecule of bacterial originGO:0071219830.012
immune response regulating signaling pathwayGO:00027641250.012
sequestering of metal ionGO:0051238190.012
tissue homeostasisGO:00018941150.012
alcohol metabolic processGO:00060661160.012
organonitrogen compound biosynthetic processGO:19015661920.012
negative regulation of growthGO:0045926990.012
sequestering of calcium ionGO:0051208180.012
respiratory system developmentGO:00605411900.012
muscle system processGO:00030121410.012
positive regulation of neuron projection developmentGO:0010976790.012
organic anion transportGO:00157111370.012
nucleoside monophosphate catabolic processGO:0009125590.012
response to transforming growth factor betaGO:0071559880.012
regulation of protein maturationGO:1903317960.011
response to lipopolysaccharideGO:00324961280.011
detection of abiotic stimulusGO:0009582600.011
positive regulation of transferase activityGO:00513471670.011
regulation of system processGO:00440572000.011
regulation of cellular response to stressGO:00801351590.011
cellular response to growth factor stimulusGO:00713631970.011
lipid localizationGO:00108761260.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
digestive system developmentGO:00551232000.011
dephosphorylationGO:00163111290.011
Mouse
positive regulation of secretionGO:00510471300.011
Worm
regulation of protein processingGO:0070613960.011
regulation of intracellular transportGO:00323861590.011
positive regulation of dna templated transcription elongationGO:003278620.011
sensory perception of mechanical stimulusGO:00509541070.011
mrna metabolic processGO:0016071840.011
positive regulation of organelle organizationGO:00106381280.011
neuronal action potentialGO:0019228540.011
cation homeostasisGO:00550802120.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
mitotic cytokinesisGO:000028140.011
myotube differentiationGO:00149021050.011
regulation of protein catabolic processGO:00421761080.011
developmental maturationGO:00217001930.011
nucleocytoplasmic transportGO:00069131390.011
insulin secretionGO:0030073890.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
glucose homeostasisGO:00425931280.011
cellular response to peptide hormone stimulusGO:0071375920.011
mitotic cell cycleGO:00002781950.011
rna interferenceGO:001624620.011
positive regulation of rho gtpase activityGO:0032321410.011
regulation of mapk cascadeGO:00434082480.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
positive regulation of ras gtpase activityGO:0032320650.011
asymmetric neuroblast divisionGO:005505910.011
regulation of chromosome organizationGO:0033044830.011
negative regulation of transferase activityGO:0051348850.011
inflammatory responseGO:00069542440.011
hormone secretionGO:00468791280.011
apoptotic signaling pathwayGO:00971903060.011
protein localization to nucleusGO:00345041210.011
fat cell differentiationGO:00454441600.011
fatty acid metabolic processGO:00066311210.011
mitotic cell cycle processGO:19030471590.011
response to inorganic substanceGO:0010035960.011
regulation of multi organism processGO:00439001110.011
response to acid chemicalGO:00011011110.011
peptide transportGO:00158331330.011
cell divisionGO:00513011200.011
telencephalon developmentGO:00215371860.011
glycoprotein metabolic processGO:00091001160.011
organophosphate ester transportGO:0015748280.011
defecationGO:003042110.011
Worm
regulation of apoptotic signaling pathwayGO:20012331970.011
regulation of actin cytoskeleton organizationGO:0032956840.011
circulatory system processGO:00030131970.011
dna repairGO:00062811070.011
gonad developmentGO:00084061410.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
myeloid leukocyte differentiationGO:00025731190.011
cellular response to cytokine stimulusGO:00713451890.011
regulation of metal ion transportGO:00109591060.011
positive regulation of cell activationGO:00508671580.011
response to nutrient levelsGO:00316671090.010
angiogenesisGO:00015252010.010
response to extracellular stimulusGO:00099911270.010
calcium ion transportGO:00068161590.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010
calcium ion homeostasisGO:00550741270.010
g protein coupled receptor signaling pathwayGO:00071862430.010
ubiquitin dependent protein catabolic processGO:00065111290.010
cellular response to peptideGO:1901653920.010
detection of external stimulusGO:0009581610.010
positive regulation of defense responseGO:00313491240.010
carboxylic acid biosynthetic processGO:0046394860.010
muscle cell differentiationGO:00426922610.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010
photoreceptor cell maintenanceGO:0045494190.010
atp catabolic processGO:0006200550.010
histone lysine methylationGO:0034968500.010
gene silencingGO:0016458380.010
peptidyl tyrosine phosphorylationGO:00181081430.010
regulation of leukocyte differentiationGO:19021051590.010
reactive oxygen species biosynthetic processGO:190340980.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
hindbrain developmentGO:00309021280.010
rac protein signal transductionGO:0016601130.010
organic hydroxy compound biosynthetic processGO:1901617770.010
positive regulation of protein catabolic processGO:0045732600.010
synaptic vesicle transportGO:0048489570.010
blood circulationGO:00080151950.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
Human
regulation of transporter activityGO:0032409570.010

Madd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.040
central nervous system diseaseDOID:33100.021
disease of metabolismDOID:001466700.014
neurodegenerative diseaseDOID:128900.013
inherited metabolic disorderDOID:65500.011