Mus musculus

0 known processes

Plekhn1

pleckstrin homology domain containing, family N member 1

(Aliases: BC025458)

Plekhn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecule catabolic processGO:00090572810.136
nucleoside phosphate metabolic processGO:00067533380.135
leukocyte differentiationGO:00025213420.104
positive regulation of cell deathGO:00109422240.101
nucleotide metabolic processGO:00091173320.099
immune response regulating signaling pathwayGO:00027641250.097
inflammatory responseGO:00069542440.093
ras protein signal transductionGO:0007265770.087
negative regulation of immune system processGO:00026832090.080
regulation of sequence specific dna binding transcription factor activityGO:00510901060.077
lymphocyte differentiationGO:00300982420.076
cellular amino acid metabolic processGO:00065201030.075
cellular response to biotic stimulusGO:0071216920.075
regulation of cellular amino acid metabolic processGO:000652150.075
amine metabolic processGO:0009308450.069
cytokine mediated signaling pathwayGO:00192211150.068
cellular response to cytokine stimulusGO:00713451890.067
glycosyl compound metabolic processGO:19016572460.066
positive regulation of programmed cell deathGO:00430682180.066
small gtpase mediated signal transductionGO:0007264970.066
cellular amine metabolic processGO:0044106440.064
purine containing compound metabolic processGO:00725213110.063
organonitrogen compound catabolic processGO:19015652640.060
t cell activationGO:00421102890.060
purine nucleotide metabolic processGO:00061633020.060
negative regulation of cell proliferationGO:00082852960.059
cellular nitrogen compound catabolic processGO:00442702800.057
organic cyclic compound catabolic processGO:19013612950.057
regulation of cellular ketone metabolic processGO:0010565660.055
positive regulation of cellular catabolic processGO:00313311480.055
positive regulation of apoptotic processGO:00430652170.054
peptidyl amino acid modificationGO:00181933360.053
protein modification by small protein conjugation or removalGO:00706472070.052
response to molecule of bacterial originGO:00022371430.052
positive regulation of protein modification processGO:00314012990.051
cellular ketone metabolic processGO:0042180840.049
apoptotic signaling pathwayGO:00971903060.049
positive regulation of cellular amine metabolic processGO:003324050.049
nucleoside triphosphate metabolic processGO:00091412300.049
aromatic compound catabolic processGO:00194392860.048
cognitionGO:00508901490.047
purine nucleoside triphosphate metabolic processGO:00091442260.047
positive regulation of cellular amino acid metabolic processGO:004576430.046
protein catabolic processGO:00301632210.046
purine nucleoside catabolic processGO:00061522050.045
protein modification by small protein conjugationGO:00324461870.045
positive regulation of cell activationGO:00508671580.045
heterocycle catabolic processGO:00467002800.045
glycosyl compound catabolic processGO:19016582060.045
purine nucleotide catabolic processGO:00061952110.045
purine nucleoside metabolic processGO:00422782410.045
positive regulation of protein phosphorylationGO:00019342420.044
nucleoside catabolic processGO:00091642060.044
organophosphate catabolic processGO:00464342320.043
multicellular organismal homeostasisGO:00488711640.043
cation transportGO:00068123990.043
innate immune response activating signal transductionGO:0002758500.043
regulation of apoptotic signaling pathwayGO:20012331970.043
negative regulation of molecular functionGO:00440922580.043
cellular response to lipopolysaccharideGO:0071222770.043
purine ribonucleoside metabolic processGO:00461282410.043
homeostasis of number of cellsGO:00488722100.043
lymphocyte activation involved in immune responseGO:0002285930.042
activation of innate immune responseGO:0002218560.042
immune effector processGO:00022523210.042
regulation of protein transportGO:00512231630.041
regulation of t cell activationGO:00508631700.041
nucleobase containing small molecule metabolic processGO:00550863520.041
positive regulation of lymphocyte activationGO:00512511400.041
locomotory behaviorGO:00076261950.040
epithelial tube formationGO:00721751300.040
nucleoside triphosphate catabolic processGO:00091432050.040
purine ribonucleoside triphosphate catabolic processGO:00092071990.040
regulation of response to woundingGO:19030341890.040
carbohydrate derivative catabolic processGO:19011362310.040
g protein coupled receptor signaling pathwayGO:00071862430.040
regulation of cell cycleGO:00517262810.039
ribonucleoside triphosphate metabolic processGO:00091992200.039
positive regulation of hydrolase activityGO:00513451480.039
purine ribonucleotide metabolic processGO:00091502900.039
cellular ion homeostasisGO:00068731650.038
regulation of cellular amine metabolic processGO:0033238200.038
cellular response to organonitrogen compoundGO:00714171450.038
dna metabolic processGO:00062593030.038
regulation of defense responseGO:00313472330.037
cell type specific apoptotic processGO:00972852680.037
ion transmembrane transportGO:00342203610.037
nucleoside phosphate catabolic processGO:19012922220.036
toll like receptor signaling pathwayGO:0002224380.036
response to lipopolysaccharideGO:00324961280.036
cellular macromolecule catabolic processGO:00442652060.036
ribonucleoside triphosphate catabolic processGO:00092031990.036
nucleoside metabolic processGO:00091162460.036
gtp catabolic processGO:00061841430.036
leukocyte activation involved in immune responseGO:00023661260.035
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
regulation of cytokine productionGO:00018172660.035
regulation of hydrolase activityGO:00513362460.035
regulation of kinase activityGO:00435492490.035
purine nucleoside triphosphate catabolic processGO:00091462030.034
t cell differentiationGO:00302171740.034
purine ribonucleoside catabolic processGO:00461302050.033
negative regulation of protein metabolic processGO:00512482820.033
b cell activationGO:00421131610.032
cellular lipid metabolic processGO:00442553230.032
cell activation involved in immune responseGO:00022631260.032
divalent inorganic cation transportGO:00725111780.032
regulation of cell projection organizationGO:00313442060.032
purine ribonucleotide catabolic processGO:00091542080.031
regulation of map kinase activityGO:00434051200.031
calcium ion homeostasisGO:00550741270.031
gtp metabolic processGO:00460391440.031
negative regulation of cell activationGO:00508661110.031
protein ubiquitinationGO:00165671710.030
nucleotide catabolic processGO:00091662170.030
purine containing compound catabolic processGO:00725232130.030
muscle tissue developmentGO:00605373080.030
leukocyte apoptotic processGO:0071887710.030
striated muscle tissue developmentGO:00147062930.029
guanosine containing compound catabolic processGO:19010691440.029
muscle cell differentiationGO:00426922610.029
interleukin 6 productionGO:0032635580.029
leukocyte proliferationGO:00706611720.029
ribose phosphate metabolic processGO:00196932910.029
ribonucleoside metabolic processGO:00091192450.029
response to radiationGO:00093141650.028
gland developmentGO:00487323300.028
regulation of lymphocyte activationGO:00512492400.028
neuron deathGO:00709971540.028
regulation of neuron differentiationGO:00456642810.028
myeloid cell homeostasisGO:00022621140.028
inorganic ion transmembrane transportGO:00986602340.028
negative regulation of cellular component organizationGO:00511291940.028
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.028
ribonucleoside catabolic processGO:00424542060.027
cytokine productionGO:00018163190.027
lymphocyte apoptotic processGO:0070227540.027
mapk cascadeGO:00001652810.027
positive regulation of cell developmentGO:00107202370.027
modification dependent protein catabolic processGO:00199411330.027
cellular chemical homeostasisGO:00550822150.027
sensory perceptionGO:00076002450.026
phospholipid metabolic processGO:0006644870.026
negative regulation of nervous system developmentGO:00519611560.026
regulation of bindingGO:00510981110.026
fat cell differentiationGO:00454441600.026
cytokine secretionGO:0050663720.026
t cell apoptotic processGO:0070231390.026
respiratory tube developmentGO:00303231670.026
regulation of inflammatory responseGO:00507271470.026
male gamete generationGO:00482322850.026
immune response activating signal transductionGO:00027571160.026
tissue homeostasisGO:00018941150.026
cellular protein catabolic processGO:00442571550.025
innate immune responseGO:00450871570.025
ribonucleotide metabolic processGO:00092592910.025
positive regulation of nucleotide metabolic processGO:00459811140.025
regulation of cell activationGO:00508652890.025
regulation of protein kinase activityGO:00458592320.024
nitrogen compound transportGO:00717052710.024
negative regulation of cellular protein metabolic processGO:00322692470.024
myotube differentiationGO:00149021050.024
regulation of protein localizationGO:00328802310.024
regulation of cellular catabolic processGO:00313292420.024
germ cell developmentGO:00072811850.024
cellular homeostasisGO:00197252400.024
ribonucleotide catabolic processGO:00092612080.024
guanosine containing compound metabolic processGO:19010681440.023
activation of mapk activity involved in innate immune responseGO:003541920.023
anatomical structure homeostasisGO:00602491450.023
actin cytoskeleton organizationGO:00300362200.023
divalent metal ion transportGO:00708381720.023
modification dependent macromolecule catabolic processGO:00436321330.023
organic hydroxy compound metabolic processGO:19016152030.023
epithelial tube morphogenesisGO:00605623030.023
negative regulation of intracellular signal transductionGO:19025321670.023
learning or memoryGO:00076111480.023
defense response to virusGO:0051607680.022
ubiquitin dependent protein catabolic processGO:00065111290.022
regulation of body fluid levelsGO:00508781620.022
negative regulation of phosphorylationGO:00423261660.022
regulation of proteolysisGO:00301621640.022
cellular metal ion homeostasisGO:00068751510.022
alpha beta t cell differentiationGO:0046632690.022
regulation of purine nucleotide catabolic processGO:00331211220.022
cellular response to lipidGO:00713961450.022
endocytosisGO:00068971680.022
regulation of nucleoside metabolic processGO:00091181300.021
inorganic cation transmembrane transportGO:00986622070.021
positive regulation of defense responseGO:00313491240.021
positive regulation of eosinophil migrationGO:200041820.021
spermatogenesisGO:00072832840.021
regulation of organelle organizationGO:00330432890.021
rho protein signal transductionGO:0007266320.021
reactive oxygen species metabolic processGO:0072593840.020
positive regulation of nervous system developmentGO:00519622210.020
regulation of protein serine threonine kinase activityGO:00719001570.020
regulation of mapk cascadeGO:00434082480.020
regulation of lymphocyte apoptotic processGO:0070228410.020
myeloid leukocyte differentiationGO:00025731190.020
pattern recognition receptor signaling pathwayGO:0002221470.020
rhythmic processGO:00485111740.020
positive regulation of gtpase activityGO:0043547850.020
epithelial cell developmentGO:00020641590.020
mitochondrion organizationGO:00070051340.020
cytoplasmic transportGO:00164822340.020
response to peptideGO:19016521360.019
positive regulation of apoptotic signaling pathwayGO:2001235950.019
protein processingGO:00164851630.019
meiotic nuclear divisionGO:00071261150.019
positive regulation of lymphocyte proliferationGO:0050671700.019
cellular component assembly involved in morphogenesisGO:00109271390.019
morphogenesis of embryonic epitheliumGO:00163311590.019
lymphocyte proliferationGO:00466511640.019
regulation of lipid metabolic processGO:00192161180.019
regulation of leukocyte differentiationGO:19021051590.019
ossificationGO:00015032160.019
response to oxidative stressGO:00069791230.019
regulation of nucleotide metabolic processGO:00061401690.019
glucose homeostasisGO:00425931280.018
activation of immune responseGO:00022531380.018
positive regulation of mapk cascadeGO:00434101700.018
carbohydrate homeostasisGO:00335001280.018
posttranscriptional regulation of gene expressionGO:00106081550.018
negative regulation of protein phosphorylationGO:00019331260.018
regulation of cytoplasmic transportGO:19036491120.018
histone modificationGO:00165701590.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
regulation of purine nucleotide metabolic processGO:19005421690.018
organonitrogen compound biosynthetic processGO:19015661920.018
chromatin modificationGO:00165681870.018
alpha beta t cell activationGO:0046631910.017
protein localization to organelleGO:00333651850.017
erythrocyte differentiationGO:0030218880.017
regulation of nucleotide catabolic processGO:00308111220.017
production of molecular mediator of immune responseGO:00024401030.017
compound eye developmentGO:004874910.017
nucleocytoplasmic transportGO:00069131390.017
cellular response to peptide hormone stimulusGO:0071375920.017
extracellular structure organizationGO:00430621480.017
regulation of transferase activityGO:00513382630.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
negative regulation of lymphocyte activationGO:0051250910.017
negative regulation of cytokine productionGO:0001818840.017
regulation of cellular response to stressGO:00801351590.017
calcium ion transportGO:00068161590.017
regulation of cell shapeGO:0008360390.017
regulation of ras gtpase activityGO:0032318880.017
osteoclast differentiationGO:0030316620.016
skeletal muscle organ developmentGO:00605381630.016
response to organic cyclic compoundGO:00140701980.016
lung developmentGO:00303241640.016
myeloid cell differentiationGO:00300992330.016
synaptic transmissionGO:00072683290.016
lipid catabolic processGO:0016042690.016
epithelial cell proliferationGO:00506731740.016
adaptive immune responseGO:00022501550.016
positive regulation of ion transportGO:0043270650.016
oxidation reduction processGO:00551143420.016
regulation of system processGO:00440572000.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
positive regulation of neuron differentiationGO:00456661410.016
regionalizationGO:00030023370.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
hematopoietic progenitor cell differentiationGO:00022441430.016
regulation of interleukin 6 productionGO:0032675550.016
positive regulation of thymocyte migrationGO:200041220.016
sequestering of metal ionGO:0051238190.016
divalent inorganic cation homeostasisGO:00725071380.016
interferon beta productionGO:0032608160.016
protein maturationGO:00516041760.016
regulation of leukocyte proliferationGO:00706631210.016
organophosphate biosynthetic processGO:00904071220.015
regulation of cell cycle processGO:00105641600.015
heart processGO:0003015940.015
organic acid biosynthetic processGO:0016053860.015
cellular protein complex assemblyGO:00436231160.015
response to peptide hormoneGO:00434341270.015
cation transmembrane transportGO:00986552660.015
organelle fissionGO:00482851700.015
regulation of establishment of protein localizationGO:00702011810.015
positive regulation of protein transportGO:0051222930.015
cation homeostasisGO:00550802120.015
protein localization to nucleusGO:00345041210.015
nuclear divisionGO:00002801580.015
lateral inhibitionGO:004633110.015
cellular response to oxidative stressGO:0034599760.015
organism emergence from protective structureGO:007168440.015
cellular response to molecule of bacterial originGO:0071219830.015
stem cell differentiationGO:00488632680.015
nuclear transportGO:00511691390.015
cellular response to dna damage stimulusGO:00069742070.015
positive regulation of gtp catabolic processGO:0033126850.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
wound healingGO:00420601570.014
tube formationGO:00351481400.014
plasma membrane organizationGO:0007009900.014
wnt signaling pathwayGO:00160551880.014
regulation of multi organism processGO:00439001110.014
detection of molecule of bacterial originGO:003249020.014
female gamete generationGO:0007292740.014
protein targetingGO:00066051430.014
proteasomal protein catabolic processGO:0010498980.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
cellular response to extracellular stimulusGO:0031668810.014
neuron apoptotic processGO:00514021420.014
regulation of gtp catabolic processGO:00331241130.014
skin developmentGO:00435882200.014
microtubule cytoskeleton organizationGO:00002261570.014
transmembrane transportGO:00550854120.014
positive regulation of proteolysisGO:0045862850.014
sequestering of calcium ionGO:0051208180.014
regulation of epithelial cell proliferationGO:00506781410.014
carboxylic acid biosynthetic processGO:0046394860.014
glycoprotein metabolic processGO:00091001160.014
thymocyte migrationGO:007267920.013
positive regulation of innate immune responseGO:0045089800.013
primary neural tube formationGO:0014020950.013
regulation of neuron apoptotic processGO:00435231220.013
regulation of secretionGO:00510462740.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
neural tube formationGO:00018411080.013
cellularizationGO:000734910.013
second messenger mediated signalingGO:0019932730.013
regulation of b cell activationGO:0050864810.013
positive regulation of organelle organizationGO:00106381280.013
negative regulation of neuron differentiationGO:00456651010.013
cellular response to organic cyclic compoundGO:0071407870.013
organelle localizationGO:00516401790.013
cellular response to hormone stimulusGO:00328701500.013
organelle assemblyGO:00709251770.013
membrane organizationGO:00610242450.013
negative regulation of inflammatory responseGO:0050728610.013
positive regulation of t cell activationGO:00508701010.013
connective tissue developmentGO:00614481790.013
gonad developmentGO:00084061410.013
heart contractionGO:0060047930.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
embryonic epithelial tube formationGO:00018381300.013
response to light stimulusGO:00094161350.013
positive regulation of nucleotide catabolic processGO:0030813880.013
regulation of cell migrationGO:00303342190.013
negative regulation of map kinase activityGO:0043407340.013
positive regulation of nucleoside metabolic processGO:0045979910.013
microtubule based processGO:00070172360.012
response to inorganic substanceGO:0010035960.012
positive regulation of cytokine productionGO:00018191740.012
peptidyl serine modificationGO:0018209830.012
covalent chromatin modificationGO:00165691630.012
regulation of eosinophil migrationGO:200041620.012
development of primary sexual characteristicsGO:00451371430.012
response to growth factorGO:00708481980.012
respiratory system developmentGO:00605411900.012
negative regulation of defense responseGO:0031348770.012
positive regulation of membrane protein ectodomain proteolysisGO:005104430.012
positive regulation of nf kappab transcription factor activityGO:0051092300.012
skeletal muscle cell differentiationGO:0035914660.012
intracellular protein transportGO:00068862040.012
mammary gland epithelium developmentGO:0061180650.012
camera type eye developmentGO:00430102660.012
stress activated protein kinase signaling cascadeGO:0031098810.012
regulation of ion transportGO:00432692150.012
negative regulation of cellular amine metabolic processGO:003323910.012
digestive tract morphogenesisGO:00485461470.012
regulation of intracellular transportGO:00323861590.012
negative regulation of t cell activationGO:0050868650.012
leukocyte migrationGO:00509001240.012
cellular response to peptideGO:1901653920.012
negative regulation of protein modification processGO:00314001630.012
maintenance of locationGO:0051235890.012
i kappab kinase nf kappab signalingGO:0007249850.012
regulation of protein catabolic processGO:00421761080.012
defecationGO:003042110.012
negative regulation of immune effector processGO:0002698550.012
response to transforming growth factor betaGO:0071559880.012
leukocyte homeostasisGO:0001776790.012
response to hostGO:007513630.012
regulation of homeostatic processGO:00328441820.011
rac protein signal transductionGO:0016601130.011
defense response to other organismGO:00985421970.011
regulation of hormone levelsGO:00108172110.011
b cell differentiationGO:0030183780.011
regulation of cellular component biogenesisGO:00440871810.011
carbohydrate derivative biosynthetic processGO:19011371830.011
negative regulation of leukocyte differentiationGO:1902106510.011
regulation of ion transmembrane transportGO:00347651190.011
protein polyubiquitinationGO:0000209330.011
canonical wnt signaling pathwayGO:00600701300.011
renal system developmentGO:00720012250.011
response to organonitrogen compoundGO:00102432460.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
response to nutrient levelsGO:00316671090.011
mitotic cell cycleGO:00002781950.011
heart morphogenesisGO:00030071780.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
response to acid chemicalGO:00011011110.011
positive regulation of protein catabolic processGO:0045732600.011
glial cell differentiationGO:00100011310.011
type i interferon productionGO:0032606290.011
regulation of nucleocytoplasmic transportGO:0046822730.011
regulation of feeding behaviorGO:006025930.011
cell substrate adhesionGO:00315891300.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
regulation of cytoskeleton organizationGO:00514931220.011
epidermis developmentGO:00085441870.011
response to extracellular stimulusGO:00099911270.011
intracellular receptor signaling pathwayGO:0030522740.011
cellular response to acid chemicalGO:0071229680.011
negative regulation of interleukin 10 secretionGO:200118020.011
gastrulationGO:00073691160.011
protein autophosphorylationGO:0046777610.011
regulation of leukocyte apoptotic processGO:2000106560.011
positive regulation of insulin secretionGO:0032024260.011
odontogenesisGO:0042476780.011
spermatid differentiationGO:00485151150.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010
single organismal cell cell adhesionGO:00163371310.010
blood circulationGO:00080151950.010
mitotic cytokinesisGO:000028140.010
viral gene expressionGO:001908030.010
placenta developmentGO:00018901400.010
anion transportGO:00068201770.010
regulation of dendritic cell apoptotic processGO:200066830.010
positive regulation of homeostatic processGO:0032846640.010
regulation of secretion by cellGO:19035302490.010
telencephalon developmentGO:00215371860.010
tube closureGO:0060606910.010
lipopolysaccharide mediated signaling pathwayGO:0031663250.010
negative regulation of neuron apoptotic processGO:0043524920.010
small molecule biosynthetic processGO:00442831320.010
negative regulation of cell developmentGO:00107211690.010
positive regulation of interleukin 6 productionGO:0032755370.010
regulation of lymphocyte differentiationGO:00456191070.010
spermatid developmentGO:00072861080.010
regulation of ras protein signal transductionGO:00465781140.010
multi multicellular organism processGO:00447061090.010
muscle system processGO:00030121410.010
peptidyl tyrosine phosphorylationGO:00181081430.010
digestive system developmentGO:00551232000.010
angiogenesisGO:00015252010.010

Plekhn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.039
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.036
eye and adnexa diseaseDOID:149200.018
sensory system diseaseDOID:005015500.018
eye diseaseDOID:561400.012
immune system diseaseDOID:291400.011