Mus musculus

33 known processes

Klhl6

kelch-like 6 (Drosophila)

(Aliases: MGC118659)

Klhl6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264970.170
ras protein signal transductionGO:0007265770.148
immune effector processGO:00022523210.117
regulation of hydrolase activityGO:00513362460.106
purine nucleotide metabolic processGO:00061633020.080
organonitrogen compound catabolic processGO:19015652640.080
rho protein signal transductionGO:0007266320.080
cellular nitrogen compound catabolic processGO:00442702800.076
ribonucleoside catabolic processGO:00424542060.076
regulation of cellular amine metabolic processGO:0033238200.075
glycosyl compound catabolic processGO:19016582060.071
organic cyclic compound catabolic processGO:19013612950.070
positive regulation of gtp catabolic processGO:0033126850.070
regulation of cellular amino acid metabolic processGO:000652150.070
nucleoside phosphate catabolic processGO:19012922220.070
regulation of cellular ketone metabolic processGO:0010565660.069
purine ribonucleotide metabolic processGO:00091502900.069
aromatic compound catabolic processGO:00194392860.068
nucleotide catabolic processGO:00091662170.068
cellular ketone metabolic processGO:0042180840.066
regulation of cytokine productionGO:00018172660.065
purine ribonucleoside metabolic processGO:00461282410.064
gtp catabolic processGO:00061841430.064
carbohydrate derivative catabolic processGO:19011362310.062
guanosine containing compound metabolic processGO:19010681440.061
amine metabolic processGO:0009308450.059
nucleoside phosphate metabolic processGO:00067533380.059
mapk cascadeGO:00001652810.059
organophosphate catabolic processGO:00464342320.059
purine ribonucleoside triphosphate metabolic processGO:00092052200.058
regulation of cell activationGO:00508652890.058
ribose phosphate metabolic processGO:00196932910.057
cellular amino acid metabolic processGO:00065201030.057
cellular amine metabolic processGO:0044106440.057
nucleobase containing small molecule metabolic processGO:00550863520.056
nucleoside triphosphate catabolic processGO:00091432050.056
negative regulation of phosphorus metabolic processGO:00105631840.056
heterocycle catabolic processGO:00467002800.056
purine nucleotide catabolic processGO:00061952110.056
purine nucleoside metabolic processGO:00422782410.056
regulation of nucleotide catabolic processGO:00308111220.055
ribonucleoside metabolic processGO:00091192450.055
positive regulation of mapk cascadeGO:00434101700.054
guanosine containing compound catabolic processGO:19010691440.054
actin cytoskeleton organizationGO:00300362200.052
regulation of cellular catabolic processGO:00313292420.051
purine ribonucleoside triphosphate catabolic processGO:00092071990.050
nucleoside catabolic processGO:00091642060.050
purine nucleoside catabolic processGO:00061522050.049
ribonucleotide metabolic processGO:00092592910.049
regulation of defense responseGO:00313472330.049
nucleotide metabolic processGO:00091173320.049
purine nucleoside triphosphate catabolic processGO:00091462030.049
purine containing compound metabolic processGO:00725213110.049
purine containing compound catabolic processGO:00725232130.048
regulation of gtp catabolic processGO:00331241130.048
purine ribonucleoside catabolic processGO:00461302050.047
ribonucleotide catabolic processGO:00092612080.047
response to lipopolysaccharideGO:00324961280.047
ribonucleoside triphosphate catabolic processGO:00092031990.046
ribonucleoside triphosphate metabolic processGO:00091992200.044
negative regulation of molecular functionGO:00440922580.044
gtp metabolic processGO:00460391440.044
regulation of organelle organizationGO:00330432890.043
nucleoside metabolic processGO:00091162460.043
t cell activationGO:00421102890.043
positive regulation of gtpase activityGO:0043547850.042
transmembrane transportGO:00550854120.042
purine nucleoside triphosphate metabolic processGO:00091442260.042
negative regulation of cellular amine metabolic processGO:003323910.041
negative regulation of phosphate metabolic processGO:00459361840.040
nucleoside triphosphate metabolic processGO:00091412300.040
cation transportGO:00068123990.040
g protein coupled receptor signaling pathwayGO:00071862430.039
regulation of mapk cascadeGO:00434082480.038
regulation of ras protein signal transductionGO:00465781140.037
purine ribonucleotide catabolic processGO:00091542080.037
positive regulation of hydrolase activityGO:00513451480.036
leukocyte proliferationGO:00706611720.036
cellular response to cytokine stimulusGO:00713451890.036
lymphocyte differentiationGO:00300982420.035
glycosyl compound metabolic processGO:19016572460.035
regulation of kinase activityGO:00435492490.034
regulation of transferase activityGO:00513382630.034
regulation of secretionGO:00510462740.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
leukocyte mediated immunityGO:00024431740.034
regulation of purine nucleotide metabolic processGO:19005421690.033
muscle cell differentiationGO:00426922610.033
cytoplasmic transportGO:00164822340.032
negative regulation of cellular protein metabolic processGO:00322692470.032
regulation of cell projection organizationGO:00313442060.032
regulation of secretion by cellGO:19035302490.032
negative regulation of protein modification processGO:00314001630.032
leukocyte differentiationGO:00025213420.032
negative regulation of phosphorylationGO:00423261660.031
endocytosisGO:00068971680.031
peptidyl amino acid modificationGO:00181933360.030
membrane organizationGO:00610242450.030
cytokine productionGO:00018163190.030
positive regulation of nucleotide catabolic processGO:0030813880.030
positive regulation of cellular amine metabolic processGO:003324050.030
hematopoietic progenitor cell differentiationGO:00022441430.030
positive regulation of cellular catabolic processGO:00313311480.030
regulation of nucleotide metabolic processGO:00061401690.029
peptidyl tyrosine modificationGO:00182121450.029
response to organonitrogen compoundGO:00102432460.029
regulation of purine nucleotide catabolic processGO:00331211220.029
cellular response to growth factor stimulusGO:00713631970.029
positive regulation of purine nucleotide metabolic processGO:19005441140.029
regulation of protein kinase activityGO:00458592320.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.028
positive regulation of purine nucleotide catabolic processGO:0033123880.028
regulation of ion transportGO:00432692150.028
regulation of cell migrationGO:00303342190.028
cellular chemical homeostasisGO:00550822150.027
inflammatory responseGO:00069542440.027
regulation of lymphocyte activationGO:00512492400.027
regulation of protein localizationGO:00328802310.027
t cell mediated immunityGO:0002456500.027
positive regulation of programmed cell deathGO:00430682180.027
ion transmembrane transportGO:00342203610.027
regulation of anatomical structure sizeGO:00900661780.026
cellular protein complex assemblyGO:00436231160.026
divalent inorganic cation transportGO:00725111780.026
positive regulation of ras gtpase activityGO:0032320650.026
immune response regulating signaling pathwayGO:00027641250.026
adaptive immune responseGO:00022501550.026
calcium ion transportGO:00068161590.026
response to growth factorGO:00708481980.026
cellular lipid metabolic processGO:00442553230.026
regulation of actin cytoskeleton organizationGO:0032956840.026
coagulationGO:0050817780.026
muscle tissue developmentGO:00605373080.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
apoptotic signaling pathwayGO:00971903060.025
cell adhesionGO:00071553290.024
regulation of nucleoside metabolic processGO:00091181300.024
sequestering of metal ionGO:0051238190.024
actin filament organizationGO:00070151130.024
regulation of inflammatory responseGO:00507271470.023
regulation of leukocyte differentiationGO:19021051590.023
macromolecule catabolic processGO:00090572810.023
positive regulation of erk1 and erk2 cascadeGO:0070374470.023
defense response to other organismGO:00985421970.023
divalent metal ion transportGO:00708381720.023
cellular homeostasisGO:00197252400.023
striated muscle tissue developmentGO:00147062930.023
inorganic cation transmembrane transportGO:00986622070.023
lymphocyte mediated immunityGO:00024491390.023
positive regulation of cytokine productionGO:00018191740.022
negative regulation of protein phosphorylationGO:00019331260.022
positive regulation of protein modification processGO:00314012990.022
circulatory system processGO:00030131970.022
leukocyte activation involved in immune responseGO:00023661260.022
positive regulation of rho gtpase activityGO:0032321410.022
positive regulation of secretion by cellGO:19035321140.022
regulation of cytoskeleton organizationGO:00514931220.022
male gamete generationGO:00482322850.022
b cell activationGO:00421131610.022
carbohydrate metabolic processGO:00059752300.021
negative regulation of protein metabolic processGO:00512482820.021
response to molecule of bacterial originGO:00022371430.021
cation homeostasisGO:00550802120.021
cellular carbohydrate metabolic processGO:00442621190.021
metal ion homeostasisGO:00550651890.021
cellular response to lipopolysaccharideGO:0071222770.021
regionalizationGO:00030023370.021
cellular response to biotic stimulusGO:0071216920.021
inorganic ion transmembrane transportGO:00986602340.021
cellular component assembly involved in morphogenesisGO:00109271390.021
lymphocyte proliferationGO:00466511640.021
regulation of ras gtpase activityGO:0032318880.021
regulation of cellular component biogenesisGO:00440871810.021
positive regulation of nucleotide metabolic processGO:00459811140.021
positive regulation of organelle organizationGO:00106381280.021
gland developmentGO:00487323300.021
regulation of cell adhesionGO:00301551540.021
regulation of rho protein signal transductionGO:0035023710.021
blood vessel morphogenesisGO:00485142850.020
regulation of body fluid levelsGO:00508781620.020
actin polymerization or depolymerizationGO:0008154540.020
regulation of protein complex assemblyGO:0043254830.020
positive regulation of secretionGO:00510471300.020
positive regulation of cell developmentGO:00107202370.020
dephosphorylationGO:00163111290.020
regulation of apoptotic signaling pathwayGO:20012331970.020
positive regulation of nucleoside metabolic processGO:0045979910.020
regulation of membrane potentialGO:00423911920.020
regulation of hormone levelsGO:00108172110.020
activation of immune responseGO:00022531380.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
cation transmembrane transportGO:00986552660.019
protein localization to organelleGO:00333651850.019
protein catabolic processGO:00301632210.019
regulation of cell motilityGO:20001452360.019
homeostasis of number of cellsGO:00488722100.019
positive regulation of cell deathGO:00109422240.019
maintenance of locationGO:0051235890.019
regulation of actin filament lengthGO:0030832450.019
t cell differentiationGO:00302171740.018
cellular response to lipidGO:00713961450.018
regulation of t cell activationGO:00508631700.018
nuclear divisionGO:00002801580.018
posttranscriptional regulation of gene expressionGO:00106081550.018
regulation of system processGO:00440572000.018
cellular response to hormone stimulusGO:00328701500.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of homeostatic processGO:00328441820.018
positive regulation of protein phosphorylationGO:00019342420.018
digestive system developmentGO:00551232000.017
negative regulation of transferase activityGO:0051348850.017
morphogenesis of embryonic epitheliumGO:00163311590.017
nitrogen compound transportGO:00717052710.017
regulation of lymphocyte differentiationGO:00456191070.017
regulation of cell cycleGO:00517262810.017
regulation of actin filament based processGO:0032970990.017
cellular metal ion homeostasisGO:00068751510.017
protein maturationGO:00516041760.017
nucleocytoplasmic transportGO:00069131390.017
sensory perceptionGO:00076002450.017
organelle localizationGO:00516401790.017
negative regulation of immune system processGO:00026832090.017
striated muscle cell developmentGO:00550021250.017
positive regulation of apoptotic processGO:00430652170.017
glucose homeostasisGO:00425931280.017
retrograde transport endosome to golgiGO:004214720.017
fibroblast growth factor receptor signaling pathwayGO:0008543460.017
regulation of protein transportGO:00512231630.017
regulation of actin polymerization or depolymerizationGO:0008064450.016
mitotic cell cycleGO:00002781950.016
spermatogenesisGO:00072832840.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
cellular ion homeostasisGO:00068731650.016
regulation of protein serine threonine kinase activityGO:00719001570.016
protein polymerizationGO:0051258570.016
organelle fissionGO:00482851700.016
protein modification by small protein conjugation or removalGO:00706472070.016
developmental maturationGO:00217001930.016
oxidation reduction processGO:00551143420.016
erk1 and erk2 cascadeGO:0070371770.016
small molecule biosynthetic processGO:00442831320.016
regulation of establishment of protein localizationGO:00702011810.016
intracellular protein transportGO:00068862040.016
synaptic transmissionGO:00072683290.015
immune response regulating cell surface receptor signaling pathwayGO:0002768800.015
myosin filament assemblyGO:003103420.015
leukocyte migrationGO:00509001240.015
cellular response to organonitrogen compoundGO:00714171450.015
meiotic cell cycleGO:00513211220.015
locomotory behaviorGO:00076261950.015
regulation of neuron differentiationGO:00456642810.015
carbohydrate derivative biosynthetic processGO:19011371830.015
alcohol metabolic processGO:00060661160.015
blood circulationGO:00080151950.015
regulation of blood circulationGO:1903522930.015
regulation of response to woundingGO:19030341890.015
hormone secretionGO:00468791280.015
tube formationGO:00351481400.015
protein targetingGO:00066051430.015
organic hydroxy compound metabolic processGO:19016152030.015
dna metabolic processGO:00062593030.015
protein localization to membraneGO:00726571080.015
carbohydrate homeostasisGO:00335001280.015
negative regulation of intracellular signal transductionGO:19025321670.015
regulation of intracellular transportGO:00323861590.014
negative regulation of kinase activityGO:0033673810.014
sequestering of calcium ionGO:0051208180.014
single organism cell adhesionGO:00986021560.014
organelle assemblyGO:00709251770.014
mitochondrion distributionGO:004831140.014
cellular response to molecule of bacterial originGO:0071219830.014
cell type specific apoptotic processGO:00972852680.014
regulation of cellular component sizeGO:00325351210.014
antigen receptor mediated signaling pathwayGO:0050851640.014
cognitionGO:00508901490.014
innate immune responseGO:00450871570.014
axonogenesisGO:00074092740.014
regulation of cytoplasmic transportGO:19036491120.014
myeloid cell differentiationGO:00300992330.014
divalent inorganic cation homeostasisGO:00725071380.014
calcium ion homeostasisGO:00550741270.014
nuclear transportGO:00511691390.014
cardiac muscle tissue developmentGO:00487381300.014
response to acid chemicalGO:00011011110.014
morphogenesis of a branching structureGO:00017632030.014
regulation of actin filament polymerizationGO:0030833380.014
myosin filament organizationGO:003103330.014
protein ubiquitinationGO:00165671710.013
neural tube closureGO:0001843900.013
regulation of proteolysisGO:00301621640.013
sensory organ morphogenesisGO:00905962420.013
regulation of erk1 and erk2 cascadeGO:0070372710.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
meiotic nuclear divisionGO:00071261150.013
hemostasisGO:0007599780.013
regulation of heart contractionGO:0008016770.013
chemotaxisGO:00069352470.013
stem cell differentiationGO:00488632680.013
cell activation involved in immune responseGO:00022631260.013
regulation of vesicle mediated transportGO:00606271390.013
blood coagulationGO:0007596760.013
tissue homeostasisGO:00018941150.013
glycerolipid metabolic processGO:00464861220.013
regulation of leukocyte mediated immunityGO:00027031040.013
striated muscle myosin thick filament assemblyGO:007168810.013
response to organic cyclic compoundGO:00140701980.013
intestinal epithelial structure maintenanceGO:006072940.013
thrombin receptor signaling pathwayGO:007049320.013
positive regulation of cellular component biogenesisGO:0044089940.013
lateral inhibitionGO:004633110.013
regulation of peptidyl tyrosine phosphorylationGO:0050730930.013
mitotic cell cycle processGO:19030471590.013
peptidyl tyrosine phosphorylationGO:00181081430.013
negative regulation of cell proliferationGO:00082852960.013
skeletal system developmentGO:00015013560.013
placenta developmentGO:00018901400.013
anion transportGO:00068201770.013
b cell proliferationGO:0042100530.013
muscle contractionGO:00069361010.013
lipid biosynthetic processGO:00086101790.013
exocytosisGO:00068871210.012
b cell differentiationGO:0030183780.012
action potentialGO:0001508780.012
wnt signaling pathwayGO:00160551880.012
regulation of rho gtpase activityGO:0032319580.012
negative regulation of cell activationGO:00508661110.012
positive regulation of cell motilityGO:20001471160.012
positive regulation of lymphocyte activationGO:00512511400.012
muscle cell developmentGO:00550011330.012
respiratory system developmentGO:00605411900.012
second messenger mediated signalingGO:0019932730.012
forebrain developmentGO:00309003020.012
mitochondrion organizationGO:00070051340.012
anatomical structure homeostasisGO:00602491450.012
regulation of b cell activationGO:0050864810.012
engulfment of apoptotic cellGO:004365230.012
synapse organizationGO:00508081250.012
camera type eye developmentGO:00430102660.012
single organismal cell cell adhesionGO:00163371310.012
fertilizationGO:00095661270.012
peptide hormone secretionGO:00300721090.012
wound healingGO:00420601570.012
protein modification by small protein conjugationGO:00324461870.012
regulation of leukocyte proliferationGO:00706631210.012
immune response activating cell surface receptor signaling pathwayGO:0002429720.012
response to inorganic substanceGO:0010035960.012
regulation of endopeptidase activityGO:0052548890.011
organophosphate biosynthetic processGO:00904071220.011
negative regulation of hydrolase activityGO:0051346710.011
ossificationGO:00015032160.011
monosaccharide metabolic processGO:00059961060.011
angiogenesisGO:00015252010.011
regulation of cell cycle processGO:00105641600.011
phospholipid metabolic processGO:0006644870.011
muscle system processGO:00030121410.011
negative regulation of cellular component organizationGO:00511291940.011
regulation of alpha beta t cell differentiationGO:0046637350.011
positive regulation of cardiac muscle contractionGO:006045220.011
regulation of intracellular protein transportGO:0033157820.011
regulation of metal ion transportGO:00109591060.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
receptor mediated endocytosisGO:0006898510.011
regulation of mitotic cell cycleGO:00073461260.011
regulation of cell divisionGO:0051302760.011
heart processGO:0003015940.011
production of molecular mediator of immune responseGO:00024401030.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
positive regulation of nervous system developmentGO:00519622210.011
negative regulation of protein maturationGO:1903318790.011
organonitrogen compound biosynthetic processGO:19015661920.011
positive regulation of alpha beta t cell activationGO:0046635390.011
regulation of transmembrane transportGO:00347621280.011
regulation of neuron projection developmentGO:00109751690.011
positive regulation of cell activationGO:00508671580.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
lymphocyte activation involved in immune responseGO:0002285930.011
modification dependent protein catabolic processGO:00199411330.011
epithelial tube morphogenesisGO:00605623030.011
positive regulation of phosphatase activityGO:001092240.011
digestive tract developmentGO:00485651900.011
negative regulation of camp mediated signalingGO:004395130.011
protein importGO:00170381010.011
monocarboxylic acid metabolic processGO:00327871910.011
multicellular organismal signalingGO:0035637910.011
positive regulation of transferase activityGO:00513471670.011
positive regulation of cell projection organizationGO:0031346950.011
glycoprotein metabolic processGO:00091001160.011
cardiac muscle contractionGO:0060048320.010
modification dependent macromolecule catabolic processGO:00436321330.010
learning or memoryGO:00076111480.010
purinergic nucleotide receptor signaling pathwayGO:003559030.010
negative regulation of lymphocyte activationGO:0051250910.010
megakaryocyte differentiationGO:0030219260.010
endomembrane system organizationGO:00102561470.010
leukocyte mediated cytotoxicityGO:0001909620.010
regulation of nucleocytoplasmic transportGO:0046822730.010
ubiquitin dependent protein catabolic processGO:00065111290.010
regulation of lymphocyte mediated immunityGO:0002706840.010
regulation of engulfment of apoptotic cellGO:190107420.010
compound eye developmentGO:004874910.010
regulation of interleukin 1 alpha productionGO:003265040.010
heart contractionGO:0060047930.010
alpha beta t cell differentiationGO:0046632690.010
respiratory tube developmentGO:00303231670.010
regulation of protein processingGO:0070613960.010
cell growthGO:00160491300.010

Klhl6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
immune system diseaseDOID:291400.017
disease of metabolismDOID:001466700.016
disease of cellular proliferationDOID:1456600.010