Mus musculus

16 known processes

Klhl2

kelch-like 2, Mayven (Drosophila)

(Aliases: KIAA4249,Mav,AU020744,mKIAA4249,ABP-KELCH,6030411N21Rik)

Klhl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleoside phosphate metabolic processGO:00067533380.111
purine nucleoside metabolic processGO:00422782410.100
cellular nitrogen compound catabolic processGO:00442702800.081
nucleobase containing small molecule metabolic processGO:00550863520.081
regulation of synaptic growth at neuromuscular junctionGO:000858240.075
purine nucleotide metabolic processGO:00061633020.072
organophosphate catabolic processGO:00464342320.070
organonitrogen compound catabolic processGO:19015652640.063
nucleotide metabolic processGO:00091173320.063
organic cyclic compound catabolic processGO:19013612950.061
purine ribonucleotide metabolic processGO:00091502900.061
cellular lipid metabolic processGO:00442553230.060
regulation of ion transportGO:00432692150.060
glycosyl compound metabolic processGO:19016572460.060
purine ribonucleoside triphosphate metabolic processGO:00092052200.059
heterocycle catabolic processGO:00467002800.056
actin cytoskeleton organizationGO:00300362200.056
protein modification by small protein conjugationGO:00324461870.054
membrane organizationGO:00610242450.052
aromatic compound catabolic processGO:00194392860.052
small gtpase mediated signal transductionGO:0007264970.052
establishment of protein localization to organelleGO:00725941180.052
melanosome localizationGO:0032400120.051
organonitrogen compound biosynthetic processGO:19015661920.050
ras protein signal transductionGO:0007265770.050
rho protein signal transductionGO:0007266320.050
positive regulation of cellular amino acid metabolic processGO:004576430.049
cellular ketone metabolic processGO:0042180840.049
regulation of cellular ketone metabolic processGO:0010565660.048
ribonucleotide metabolic processGO:00092592910.048
positive regulation of cellular catabolic processGO:00313311480.045
lipid localizationGO:00108761260.044
regulation of cellular component biogenesisGO:00440871810.044
peptidyl amino acid modificationGO:00181933360.042
purine containing compound metabolic processGO:00725213110.042
ribose phosphate metabolic processGO:00196932910.041
endomembrane system organizationGO:00102561470.041
nucleotide catabolic processGO:00091662170.041
nucleoside metabolic processGO:00091162460.041
negative regulation of cell proliferationGO:00082852960.040
regulation of cell motilityGO:20001452360.040
carbohydrate metabolic processGO:00059752300.039
regionalizationGO:00030023370.039
regulation of purine nucleotide metabolic processGO:19005421690.038
regulation of purine nucleotide catabolic processGO:00331211220.037
axonogenesisGO:00074092740.037
glycosyl compound catabolic processGO:19016582060.037
dephosphorylationGO:00163111290.036
glycerolipid metabolic processGO:00464861220.036
protein targetingGO:00066051430.036
wnt signaling pathwayGO:00160551880.035
positive regulation of nucleotide metabolic processGO:00459811140.035
purine containing compound catabolic processGO:00725232130.034
cellular amino acid metabolic processGO:00065201030.034
regulation of cellular amino acid metabolic processGO:000652150.033
intracellular protein transportGO:00068862040.033
lipid transportGO:0006869980.033
nucleoside phosphate catabolic processGO:19012922220.033
nucleoside catabolic processGO:00091642060.033
regulation of cellular amine metabolic processGO:0033238200.032
protein localization to organelleGO:00333651850.032
mitotic cell cycleGO:00002781950.032
actin filament organizationGO:00070151130.032
cation transportGO:00068123990.032
negative regulation of phosphorus metabolic processGO:00105631840.032
rac protein signal transductionGO:0016601130.032
nucleotide sugar metabolic processGO:000922540.031
purine ribonucleoside metabolic processGO:00461282410.031
ribonucleoside triphosphate metabolic processGO:00091992200.031
purine ribonucleoside triphosphate catabolic processGO:00092071990.031
endocytosisGO:00068971680.031
lymphocyte differentiationGO:00300982420.031
purine ribonucleotide catabolic processGO:00091542080.030
ion transmembrane transportGO:00342203610.030
regulation of hydrolase activityGO:00513362460.029
positive regulation of hydrolase activityGO:00513451480.029
nucleoside triphosphate catabolic processGO:00091432050.029
nucleocytoplasmic transportGO:00069131390.029
phosphatidylinositol metabolic processGO:0046488450.029
regulation of anatomical structure sizeGO:00900661780.029
regulation of organelle organizationGO:00330432890.028
establishment of protein localization to vacuoleGO:007266640.028
purine nucleoside triphosphate catabolic processGO:00091462030.028
t cell activationGO:00421102890.028
ribonucleotide catabolic processGO:00092612080.028
guanosine containing compound metabolic processGO:19010681440.028
regulation of ion transmembrane transportGO:00347651190.028
transmembrane transportGO:00550854120.027
regulation of neuron differentiationGO:00456642810.027
positive regulation of cellular amine metabolic processGO:003324050.027
lipid homeostasisGO:0055088630.027
positive regulation of purine nucleotide metabolic processGO:19005441140.027
leukocyte differentiationGO:00025213420.027
nitrogen compound transportGO:00717052710.027
camera type eye developmentGO:00430102660.026
g protein coupled receptor signaling pathwayGO:00071862430.026
regulation of transmembrane transportGO:00347621280.026
regulation of membrane potentialGO:00423911920.026
regulation of ras gtpase activityGO:0032318880.026
gtp metabolic processGO:00460391440.026
establishment of vesicle localizationGO:0051650810.025
morphogenesis of embryonic epitheliumGO:00163311590.025
lipid biosynthetic processGO:00086101790.025
establishment or maintenance of cell polarityGO:0007163860.025
cell type specific apoptotic processGO:00972852680.025
dendrite developmentGO:00163581150.024
regulation of nucleotide metabolic processGO:00061401690.024
regulation of cell projection organizationGO:00313442060.024
purine nucleoside triphosphate metabolic processGO:00091442260.024
purine nucleotide catabolic processGO:00061952110.024
cofactor metabolic processGO:0051186800.024
sensory perceptionGO:00076002450.024
nuclear divisionGO:00002801580.024
carbohydrate derivative biosynthetic processGO:19011371830.024
protein ubiquitinationGO:00165671710.024
ribonucleoside metabolic processGO:00091192450.024
synapse organizationGO:00508081250.023
cell adhesionGO:00071553290.023
guanosine containing compound catabolic processGO:19010691440.023
localization within membraneGO:005166840.023
positive regulation of nervous system developmentGO:00519622210.023
inositol phosphate catabolic processGO:007154540.023
positive regulation of growthGO:00459271040.023
organic hydroxy compound metabolic processGO:19016152030.023
ribonucleoside catabolic processGO:00424542060.023
carbohydrate derivative catabolic processGO:19011362310.023
homeostasis of number of cellsGO:00488722100.023
transmission of nerve impulseGO:0019226760.023
response to organonitrogen compoundGO:00102432460.023
cellular homeostasisGO:00197252400.022
oocyte constructionGO:000730820.022
amine metabolic processGO:0009308450.022
sensory perception of soundGO:0007605970.022
chemotaxisGO:00069352470.022
regulation of nucleotide catabolic processGO:00308111220.022
positive regulation of cellular component biogenesisGO:0044089940.021
negative regulation of phosphate metabolic processGO:00459361840.021
intracellular lipid transportGO:003236530.021
maintenance of locationGO:0051235890.021
chromatin organizationGO:00063252060.021
glycerophospholipid metabolic processGO:0006650710.020
pole plasm assemblyGO:000731520.020
regulation of cellular catabolic processGO:00313292420.020
cellular response to organonitrogen compoundGO:00714171450.020
cellular ion homeostasisGO:00068731650.020
oxidation reduction processGO:00551143420.020
cation transmembrane transportGO:00986552660.020
positive regulation of cell projection organizationGO:0031346950.020
protein localization to nucleusGO:00345041210.020
regulation of cytokine productionGO:00018172660.020
cellular carbohydrate metabolic processGO:00442621190.020
synaptic transmissionGO:00072683290.020
exocytosisGO:00068871210.020
multicellular organismal homeostasisGO:00488711640.019
nucleoside triphosphate metabolic processGO:00091412300.019
blood vessel morphogenesisGO:00485142850.019
positive regulation of purine nucleotide catabolic processGO:0033123880.019
cell divisionGO:00513011200.019
cytoplasmic transportGO:00164822340.019
membrane tubulationGO:009732040.019
cellular amine metabolic processGO:0044106440.019
phospholipid metabolic processGO:0006644870.019
regulation of cellular component sizeGO:00325351210.019
regulation of intracellular transportGO:00323861590.019
organophosphate biosynthetic processGO:00904071220.019
meiotic cell cycleGO:00513211220.019
protein catabolic processGO:00301632210.019
positive regulation of programmed cell deathGO:00430682180.019
regulation of transporter activityGO:0032409570.019
negative regulation of cell sizeGO:004579230.019
carbohydrate homeostasisGO:00335001280.018
establishment of melanosome localizationGO:0032401110.018
positive regulation of proteolysisGO:0045862850.018
purine ribonucleoside catabolic processGO:00461302050.018
lipid modificationGO:0030258650.018
regulation of rho gtpase activityGO:0032319580.018
nuclear transportGO:00511691390.018
gtp catabolic processGO:00061841430.018
regulation of cell activationGO:00508652890.018
negative regulation of synapse assemblyGO:005196430.018
leukocyte homeostasisGO:0001776790.018
peptidyl serine modificationGO:0018209830.018
inorganic cation transmembrane transportGO:00986622070.018
peptide transportGO:00158331330.018
negative regulation of protein metabolic processGO:00512482820.018
positive regulation of nucleotide catabolic processGO:0030813880.018
purine nucleoside catabolic processGO:00061522050.018
cellular response to hormone stimulusGO:00328701500.018
organelle localizationGO:00516401790.017
regulation of nucleoside metabolic processGO:00091181300.017
regulation of kinase activityGO:00435492490.017
action potentialGO:0001508780.017
negative regulation of intracellular signal transductionGO:19025321670.017
oocyte axis specificationGO:000730920.017
gland developmentGO:00487323300.017
fatty acid metabolic processGO:00066311210.017
alcohol metabolic processGO:00060661160.017
angiogenesisGO:00015252010.017
regulation of mapk cascadeGO:00434082480.017
microtubule cytoskeleton organizationGO:00002261570.017
regulation of engulfment of apoptotic cellGO:190107420.017
skeletal system developmentGO:00015013560.017
myeloid cell differentiationGO:00300992330.017
maternal determination of anterior posterior axis embryoGO:000835820.017
neuronal action potentialGO:0019228540.017
protein localization to endosomeGO:003601020.017
inorganic ion transmembrane transportGO:00986602340.017
regulation of lipid transportGO:0032368360.016
microtubule based processGO:00070172360.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
hematopoietic progenitor cell differentiationGO:00022441430.016
macromolecule catabolic processGO:00090572810.016
divalent inorganic cation transportGO:00725111780.016
cellular protein complex assemblyGO:00436231160.016
udp n acetylglucosamine metabolic processGO:000604730.016
positive regulation of ras gtpase activityGO:0032320650.016
cellularizationGO:000734910.016
lymphocyte activation involved in immune responseGO:0002285930.016
striated muscle tissue developmentGO:00147062930.016
cellular chemical homeostasisGO:00550822150.016
regulation of secretionGO:00510462740.016
nuclear importGO:0051170950.016
lymphocyte proliferationGO:00466511640.016
regulation of cell migrationGO:00303342190.016
female gamete generationGO:0007292740.016
positive regulation of gtp catabolic processGO:0033126850.016
regulation of cellular response to stressGO:00801351590.016
negative regulation of cellular protein metabolic processGO:00322692470.016
cell activation involved in immune responseGO:00022631260.015
regulation of cell sizeGO:0008361720.015
cellular response to biotic stimulusGO:0071216920.015
regulation of leukocyte differentiationGO:19021051590.015
plasma membrane organizationGO:0007009900.015
ossificationGO:00015032160.015
protein localization to membraneGO:00726571080.015
regulation of protein kinase b signalingGO:0051896560.015
development of primary sexual characteristicsGO:00451371430.015
regulation of metal ion transportGO:00109591060.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of rho protein signal transductionGO:0035023710.015
mitotic cell cycle processGO:19030471590.015
regulation of protein targetingGO:1903533610.015
glucose homeostasisGO:00425931280.015
negative regulation of molecular functionGO:00440922580.015
protein targeting to vacuoleGO:000662330.015
small molecule biosynthetic processGO:00442831320.015
divalent metal ion transportGO:00708381720.014
regulation of protein localizationGO:00328802310.014
negative regulation of cell migrationGO:0030336590.014
positive regulation of phagocytosis engulfmentGO:006010030.014
positive regulation of cell developmentGO:00107202370.014
respiratory tube developmentGO:00303231670.014
fertilizationGO:00095661270.014
cell maturationGO:00484691270.014
ensheathment of neuronsGO:0007272760.014
axon guidanceGO:00074111410.014
organelle fissionGO:00482851700.014
protein localization to vacuoleGO:007266540.014
apoptotic signaling pathwayGO:00971903060.014
response to radiationGO:00093141650.014
negative regulation of cellular component organizationGO:00511291940.014
compound eye developmentGO:004874910.014
multicellular organismal signalingGO:0035637910.014
protein kinase b signalingGO:0043491740.014
neural precursor cell proliferationGO:00613511210.014
regulation of neuron projection developmentGO:00109751690.014
positive regulation of secretionGO:00510471300.014
regulation of cytoplasmic transportGO:19036491120.014
retrograde transport endosome to golgiGO:004214720.014
monocarboxylic acid metabolic processGO:00327871910.014
intracellular mrna localizationGO:000829840.014
forebrain developmentGO:00309003020.014
regulation of dna damage checkpointGO:200000130.014
myosin filament organizationGO:003103330.014
positive regulation of organelle organizationGO:00106381280.014
sterol transportGO:0015918380.014
regulation of intracellular protein transportGO:0033157820.014
positive regulation of protein modification processGO:00314012990.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
protein modification by small protein conjugation or removalGO:00706472070.013
stem cell differentiationGO:00488632680.013
positive regulation of nucleoside metabolic processGO:0045979910.013
regulation of gtp catabolic processGO:00331241130.013
protein importGO:00170381010.013
regulation of proteolysisGO:00301621640.013
t cell differentiationGO:00302171740.013
peptidyl serine phosphorylationGO:0018105740.013
cognitionGO:00508901490.013
response to peptideGO:19016521360.013
positive regulation of rho gtpase activityGO:0032321410.013
negative regulation of protein phosphorylationGO:00019331260.013
positive regulation of apoptotic processGO:00430652170.013
negative regulation of phosphorylationGO:00423261660.013
positive regulation of gtpase activityGO:0043547850.013
reactive oxygen species metabolic processGO:0072593840.013
myotube differentiationGO:00149021050.013
golgi to endosome transportGO:000689530.013
peptidyl tyrosine phosphorylationGO:00181081430.013
immune effector processGO:00022523210.013
negative regulation of cell cycleGO:00457861230.013
calcium ion homeostasisGO:00550741270.013
regulation of cell cycleGO:00517262810.013
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.013
peptide hormone secretionGO:00300721090.013
hormone secretionGO:00468791280.013
organic acid biosynthetic processGO:0016053860.013
vesicle localizationGO:0051648860.013
negative regulation of neuron deathGO:1901215980.013
cellular response to growth factor stimulusGO:00713631970.013
rhythmic processGO:00485111740.013
positive regulation of smooth muscle cell migrationGO:001491140.013
cofactor biosynthetic processGO:0051188410.013
establishment of protein localization to membraneGO:0090150540.013
positive regulation of glycolytic processGO:004582140.013
respiratory system developmentGO:00605411900.012
regulation of synaptic plasticityGO:0048167870.012
cell cycle switching mitotic to meiotic cell cycleGO:005172810.012
early endosome to late endosome transportGO:004502220.012
carboxylic acid biosynthetic processGO:0046394860.012
chromatin modificationGO:00165681870.012
locomotory behaviorGO:00076261950.012
regulation of exocytosisGO:0017157610.012
generation of precursor metabolites and energyGO:00060911030.012
activation of adenylate cyclase activityGO:000719040.012
regulation of lymphocyte differentiationGO:00456191070.012
neuron projection guidanceGO:00974851410.012
ubiquitin dependent protein catabolic processGO:00065111290.012
regulation of neuronal synaptic plasticityGO:0048168300.012
establishment of pigment granule localizationGO:0051905120.012
skeletal muscle organ developmentGO:00605381630.012
regulation of interferon beta biosynthetic processGO:004535740.012
meiotic nuclear divisionGO:00071261150.012
mapk cascadeGO:00001652810.012
cytokinetic processGO:003250620.012
regulation of t cell differentiationGO:0045580830.012
regulation of hormone levelsGO:00108172110.012
fat cell differentiationGO:00454441600.012
carbohydrate biosynthetic processGO:0016051740.012
covalent chromatin modificationGO:00165691630.012
response to organic cyclic compoundGO:00140701980.012
organic hydroxy compound transportGO:0015850930.012
positive regulation of protein kinase activityGO:00458601440.012
single organism nuclear importGO:1902593950.012
actin filament bundle assemblyGO:0051017400.012
sulfur compound metabolic processGO:00067901000.012
skin developmentGO:00435882200.012
methylationGO:00322591340.012
regulation of protein kinase activityGO:00458592320.012
tissue homeostasisGO:00018941150.012
response to light stimulusGO:00094161350.012
mrna metabolic processGO:0016071840.012
regulation of epithelial cell proliferationGO:00506781410.012
regulation of cell growthGO:0001558910.012
regulation of t cell activationGO:00508631700.012
phosphorylated carbohydrate dephosphorylationGO:004683840.012
coenzyme biosynthetic processGO:0009108230.012
regulation of protein transportGO:00512231630.011
learning or memoryGO:00076111480.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
cytokine productionGO:00018163190.011
regulation of ras protein signal transductionGO:00465781140.011
cell cycle switchingGO:006018410.011
vesicle organizationGO:0016050600.011
myeloid leukocyte differentiationGO:00025731190.011
positive regulation of transcription from rna polymerase i promoterGO:004594330.011
neuron apoptotic processGO:00514021420.011
regulation of defense responseGO:00313472330.011
tube formationGO:00351481400.011
epidermis developmentGO:00085441870.011
modification dependent protein catabolic processGO:00199411330.011
gonad developmentGO:00084061410.011
meiotic cell cycle processGO:1903046770.011
skeletal system morphogenesisGO:00487052030.011
axon ensheathmentGO:0008366760.011
regulation of feeding behaviorGO:006025930.011
epithelial cell proliferationGO:00506731740.011
regulation of system processGO:00440572000.011
regulation of vasculature developmentGO:1901342880.011
activation of immune responseGO:00022531380.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of transferase activityGO:00513382630.011
posttranscriptional regulation of gene expressionGO:00106081550.011
response to insulinGO:00328681000.011
interferon beta biosynthetic processGO:004535040.011
muscle tissue developmentGO:00605373080.011
cellular protein catabolic processGO:00442571550.011
negative regulation of secretionGO:0051048610.011
regulation of secretion by cellGO:19035302490.011
regulation of interleukin 8 productionGO:003267730.011
purine containing compound biosynthetic processGO:0072522700.011
acetylcholine transportGO:001587020.011
modification dependent macromolecule catabolic processGO:00436321330.011
multi multicellular organism processGO:00447061090.011
neuron deathGO:00709971540.011
negative regulation of growthGO:0045926990.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
p38mapk cascadeGO:003806640.011
regulation of lymphocyte activationGO:00512492400.011
limb morphogenesisGO:00351081490.010
segmentationGO:0035282930.010
leukocyte activation involved in immune responseGO:00023661260.010
cell growthGO:00160491300.010
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.010
positive regulation of protein catabolic processGO:0045732600.010
digestionGO:0007586400.010
actomyosin structure organizationGO:0031032560.010
sensory organ morphogenesisGO:00905962420.010
response to extracellular stimulusGO:00099911270.010
central nervous system neuron differentiationGO:00219531620.010
positive regulation of cell deathGO:00109422240.010
regulation of protein catabolic processGO:00421761080.010
inflammatory responseGO:00069542440.010
amide transportGO:00428861380.010
response to inorganic substanceGO:0010035960.010
cell agingGO:0007569350.010
positive regulation of engulfment of apoptotic cellGO:190107610.010
histone modificationGO:00165701590.010
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.010
cellular amino acid biosynthetic processGO:0008652220.010
cellular response to peptide hormone stimulusGO:0071375920.010
striated muscle myosin thick filament assemblyGO:007168810.010
regulation of bindingGO:00510981110.010
regulation of cell morphogenesis involved in differentiationGO:00107691510.010
leukocyte proliferationGO:00706611720.010
ameboidal type cell migrationGO:00016671280.010
negative regulation of protein modification processGO:00314001630.010
regulation of cell adhesionGO:00301551540.010
cellular metal ion homeostasisGO:00068751510.010
regulation of cellular carbohydrate metabolic processGO:0010675750.010
stem cell developmentGO:00488642190.010

Klhl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.017
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
organ system cancerDOID:005068600.010
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010