Mus musculus

70 known processes

Phgdh

3-phosphoglycerate dehydrogenase

(Aliases: PGD,A10,3-PGDH,MGC117966,PGDH,MGC113796,SERA,PGAD,3PGDH,4930479N23)

Phgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.151
cellular ketone metabolic processGO:0042180840.106
purine nucleobase biosynthetic processGO:000911330.105
cellular amine metabolic processGO:0044106440.067
positive regulation of cellular amino acid metabolic processGO:004576430.059
negative regulation of protein metabolic processGO:00512482820.051
mapk cascadeGO:00001652810.051
regulation of cellular ketone metabolic processGO:0010565660.050
negative regulation of cellular protein metabolic processGO:00322692470.049
cellular response to dna damage stimulusGO:00069742070.046
organic cyclic compound catabolic processGO:19013612950.043
male gamete generationGO:00482322850.041
amine metabolic processGO:0009308450.040
positive regulation of cellular amine metabolic processGO:003324050.040
peptidyl tyrosine modificationGO:00182121450.040
regulation of protein kinase activityGO:00458592320.038
chromatin organizationGO:00063252060.037
regulation of kinase activityGO:00435492490.037
regulation of cellular amine metabolic processGO:0033238200.036
peptidyl amino acid modificationGO:00181933360.036
positive regulation of protein phosphorylationGO:00019342420.035
nitrogen compound transportGO:00717052710.034
heterocycle catabolic processGO:00467002800.033
purine nucleobase metabolic processGO:000614440.032
organonitrogen compound biosynthetic processGO:19015661920.032
lymphocyte mediated immunityGO:00024491390.031
positive regulation of apoptotic processGO:00430652170.028
small gtpase mediated signal transductionGO:0007264970.027
negative regulation of protein modification processGO:00314001630.026
regulation of organelle organizationGO:00330432890.026
anion transportGO:00068201770.026
aromatic compound catabolic processGO:00194392860.026
regulation of mapk cascadeGO:00434082480.026
organic acid transportGO:00158491010.025
positive regulation of protein modification processGO:00314012990.025
regulation of cellular amino acid metabolic processGO:000652150.025
leukocyte mediated immunityGO:00024431740.025
purine ribonucleoside metabolic processGO:00461282410.025
folic acid containing compound metabolic processGO:000676030.024
leukocyte proliferationGO:00706611720.024
negative regulation of phosphorylationGO:00423261660.024
carboxylic acid biosynthetic processGO:0046394860.023
purine nucleotide metabolic processGO:00061633020.023
ras protein signal transductionGO:0007265770.023
dna recombinationGO:0006310920.023
nucleobase containing small molecule metabolic processGO:00550863520.023
cellular homeostasisGO:00197252400.023
inflammatory responseGO:00069542440.022
cellular amino acid biosynthetic processGO:0008652220.022
cellular nitrogen compound catabolic processGO:00442702800.022
cell maturationGO:00484691270.022
nucleoside triphosphate catabolic processGO:00091432050.022
alpha amino acid biosynthetic processGO:1901607150.021
alpha amino acid metabolic processGO:1901605590.021
oxidation reduction processGO:00551143420.021
defense response to other organismGO:00985421970.021
regulation of defense responseGO:00313472330.021
organophosphate catabolic processGO:00464342320.020
translationGO:0006412930.020
organic acid biosynthetic processGO:0016053860.020
microtubule based processGO:00070172360.020
transmembrane transportGO:00550854120.019
negative regulation of molecular functionGO:00440922580.019
carbohydrate metabolic processGO:00059752300.019
cytoplasmic transportGO:00164822340.019
nucleoside triphosphate metabolic processGO:00091412300.019
nucleoside metabolic processGO:00091162460.018
regulation of cell projection organizationGO:00313442060.018
regulation of transferase activityGO:00513382630.018
epithelial cell developmentGO:00020641590.018
endocytosisGO:00068971680.018
compound eye developmentGO:004874910.018
positive regulation of transferase activityGO:00513471670.017
organelle fissionGO:00482851700.017
purine containing compound metabolic processGO:00725213110.017
regulation of response to woundingGO:19030341890.017
glycosyl compound catabolic processGO:19016582060.017
immune effector processGO:00022523210.017
peptidyl tyrosine phosphorylationGO:00181081430.016
spermatogenesisGO:00072832840.016
regulation of neuron differentiationGO:00456642810.016
small molecule biosynthetic processGO:00442831320.016
protein processingGO:00164851630.016
regulation of protein serine threonine kinase activityGO:00719001570.016
regulation of secretionGO:00510462740.016
regulation of neuron deathGO:19012141340.016
glycosyl compound metabolic processGO:19016572460.016
regulation of secretion by cellGO:19035302490.016
positive regulation of immune effector processGO:00026991070.016
carbohydrate homeostasisGO:00335001280.016
regulation of cytokine productionGO:00018172660.016
lateral inhibitionGO:004633110.016
purine ribonucleoside catabolic processGO:00461302050.016
response to organonitrogen compoundGO:00102432460.016
chemotaxisGO:00069352470.016
negative regulation of protein processingGO:0010955790.016
cellular response to lipidGO:00713961450.016
organonitrogen compound catabolic processGO:19015652640.015
t cell activationGO:00421102890.015
regulation of chromosome organizationGO:0033044830.015
ribose phosphate metabolic processGO:00196932910.015
b cell activationGO:00421131610.015
organic hydroxy compound metabolic processGO:19016152030.015
ion transmembrane transportGO:00342203610.015
cellular macromolecule catabolic processGO:00442652060.015
positive regulation of protein kinase activityGO:00458601440.014
regulation of cellular component sizeGO:00325351210.014
morphogenesis of a branching structureGO:00017632030.014
regulation of protein maturationGO:1903317960.014
sensory perceptionGO:00076002450.014
nucleoside catabolic processGO:00091642060.014
mrna metabolic processGO:0016071840.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
nucleotide metabolic processGO:00091173320.014
ribonucleotide catabolic processGO:00092612080.014
regulation of circadian sleep wake cycle sleepGO:004518730.014
monocarboxylic acid metabolic processGO:00327871910.014
cell divisionGO:00513011200.014
carbohydrate derivative catabolic processGO:19011362310.014
regulation of anatomical structure sizeGO:00900661780.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
regulation of cell activationGO:00508652890.014
hatchingGO:003518840.013
mitotic cell cycle processGO:19030471590.013
gonad developmentGO:00084061410.013
posttranscriptional regulation of gene expressionGO:00106081550.013
regulation of hormone levelsGO:00108172110.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
production of molecular mediator of immune responseGO:00024401030.013
maintenance of locationGO:0051235890.013
alcohol metabolic processGO:00060661160.013
developmental maturationGO:00217001930.013
lymphocyte proliferationGO:00466511640.013
meiotic nuclear divisionGO:00071261150.013
regulation of cell morphogenesis involved in differentiationGO:00107691510.013
regulation of ion transportGO:00432692150.013
germ cell developmentGO:00072811850.013
nucleoside phosphate catabolic processGO:19012922220.013
regulation of cell cycleGO:00517262810.013
purine nucleoside metabolic processGO:00422782410.013
positive regulation of neuron differentiationGO:00456661410.012
response to light stimulusGO:00094161350.012
stem cell proliferationGO:00720891170.012
cell type specific apoptotic processGO:00972852680.012
ribonucleoside metabolic processGO:00091192450.012
purine ribonucleotide metabolic processGO:00091502900.012
regulation of cell cycle processGO:00105641600.012
membrane organizationGO:00610242450.012
negative regulation of proteolysisGO:0045861740.012
carboxylic acid transportGO:00469421000.012
organelle assemblyGO:00709251770.012
regulation of cell sizeGO:0008361720.012
negative regulation of immune system processGO:00026832090.012
regulation of cellular response to stressGO:00801351590.012
nucleotide catabolic processGO:00091662170.012
oocyte constructionGO:000730820.011
gliogenesisGO:00420631410.011
axonogenesisGO:00074092740.011
negative regulation of phosphorus metabolic processGO:00105631840.011
dephosphorylationGO:00163111290.011
regulation of vesicle mediated transportGO:00606271390.011
regulation of protein localizationGO:00328802310.011
apoptotic signaling pathwayGO:00971903060.011
nucleobase biosynthetic processGO:004611230.011
anatomical structure homeostasisGO:00602491450.011
negative regulation of nervous system developmentGO:00519611560.011
regulation of hydrolase activityGO:00513362460.011
positive regulation of kinase activityGO:00336741550.011
cellular chemical homeostasisGO:00550822150.011
glial cell differentiationGO:00100011310.011
regulation of interleukin 6 productionGO:0032675550.011
striated muscle tissue developmentGO:00147062930.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
regulation of erk1 and erk2 cascadeGO:0070372710.011
regulation of engulfment of apoptotic cellGO:190107420.011
negative regulation of protein maturationGO:1903318790.011
leukocyte differentiationGO:00025213420.011
camera type eye developmentGO:00430102660.011
nuclear divisionGO:00002801580.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
neuron apoptotic processGO:00514021420.011
reactive oxygen species metabolic processGO:0072593840.011
rna processingGO:00063961050.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.010
nuclear dna replicationGO:003326030.010
positive regulation of cytokine productionGO:00018191740.010
cellularizationGO:000734910.010
response to lipopolysaccharideGO:00324961280.010
nucleoside phosphate metabolic processGO:00067533380.010
coenzyme metabolic processGO:0006732520.010
regulation of neuron projection developmentGO:00109751690.010
gland developmentGO:00487323300.010
actin cytoskeleton organizationGO:00300362200.010
digestive tract developmentGO:00485651900.010
dna repairGO:00062811070.010
chromatin modificationGO:00165681870.010
cation transportGO:00068123990.010
microtubule cytoskeleton organizationGO:00002261570.010
response to organic cyclic compoundGO:00140701980.010
response to peptideGO:19016521360.010
regionalizationGO:00030023370.010
positive regulation of programmed cell deathGO:00430682180.010

Phgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
disease of metabolismDOID:001466700.020
Human
inherited metabolic disorderDOID:65500.020
Human
organ system cancerDOID:005068600.016
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013