Mus musculus

0 known processes

Cdc42se2

CDC42 small effector 2

(Aliases: AA408783,SPEC2,AA536669,2810404F18Rik)

Cdc42se2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238200.167
cellular amino acid metabolic processGO:00065201030.143
cellular amine metabolic processGO:0044106440.124
regulation of cellular amino acid metabolic processGO:000652150.115
regulation of cellular ketone metabolic processGO:0010565660.103
amine metabolic processGO:0009308450.098
ras protein signal transductionGO:0007265770.082
ribonucleoside metabolic processGO:00091192450.081
nucleoside phosphate metabolic processGO:00067533380.078
peptidyl amino acid modificationGO:00181933360.077
cellular ketone metabolic processGO:0042180840.076
gtp catabolic processGO:00061841430.074
purine containing compound metabolic processGO:00725213110.071
purine nucleotide metabolic processGO:00061633020.067
heterocycle catabolic processGO:00467002800.063
actin cytoskeleton organizationGO:00300362200.063
glycosyl compound metabolic processGO:19016572460.062
ribose phosphate metabolic processGO:00196932910.060
positive regulation of protein modification processGO:00314012990.060
nucleoside metabolic processGO:00091162460.060
regulation of kinase activityGO:00435492490.059
ribonucleotide catabolic processGO:00092612080.056
mapk cascadeGO:00001652810.056
purine ribonucleotide metabolic processGO:00091502900.055
purine containing compound catabolic processGO:00725232130.055
regulation of protein kinase activityGO:00458592320.054
ribonucleoside catabolic processGO:00424542060.052
negative regulation of cellular amine metabolic processGO:003323910.051
nucleoside catabolic processGO:00091642060.051
aromatic compound catabolic processGO:00194392860.049
ribonucleoside triphosphate catabolic processGO:00092031990.048
purine nucleoside triphosphate catabolic processGO:00091462030.047
regulation of transferase activityGO:00513382630.047
organic cyclic compound catabolic processGO:19013612950.047
purine nucleoside metabolic processGO:00422782410.046
regulation of cell cycleGO:00517262810.046
organonitrogen compound catabolic processGO:19015652640.046
regulation of synaptic growth at neuromuscular junctionGO:000858240.045
ribonucleotide metabolic processGO:00092592910.045
nucleoside phosphate catabolic processGO:19012922220.044
nucleobase containing small molecule metabolic processGO:00550863520.044
nucleotide metabolic processGO:00091173320.043
cell type specific apoptotic processGO:00972852680.042
apoptotic signaling pathwayGO:00971903060.042
regulation of organelle organizationGO:00330432890.041
regulation of purine nucleotide metabolic processGO:19005421690.040
purine ribonucleoside metabolic processGO:00461282410.040
cytoplasmic transportGO:00164822340.040
positive regulation of cellular amine metabolic processGO:003324050.040
nucleotide catabolic processGO:00091662170.039
protein modification by small protein conjugation or removalGO:00706472070.039
carbohydrate derivative biosynthetic processGO:19011371830.039
organelle fissionGO:00482851700.039
regulation of t cell activationGO:00508631700.038
regulation of defense responseGO:00313472330.038
positive regulation of protein phosphorylationGO:00019342420.038
ion transmembrane transportGO:00342203610.038
regulation of cell motilityGO:20001452360.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
positive regulation of cell developmentGO:00107202370.037
protein autophosphorylationGO:0046777610.037
small gtpase mediated signal transductionGO:0007264970.037
regulation of cell projection organizationGO:00313442060.037
organophosphate catabolic processGO:00464342320.036
protein modification by small protein conjugationGO:00324461870.036
rho protein signal transductionGO:0007266320.036
negative regulation of cellular component organizationGO:00511291940.036
negative regulation of molecular functionGO:00440922580.035
rap protein signal transductionGO:003248630.034
immune effector processGO:00022523210.034
cellular protein complex assemblyGO:00436231160.034
organonitrogen compound biosynthetic processGO:19015661920.034
nucleoside triphosphate metabolic processGO:00091412300.033
regulation of cell activationGO:00508652890.033
regulation of lymphocyte activationGO:00512492400.033
nucleoside triphosphate catabolic processGO:00091432050.032
negative regulation of phosphorylationGO:00423261660.032
carbohydrate derivative catabolic processGO:19011362310.032
cellular homeostasisGO:00197252400.032
cation transportGO:00068123990.032
dorsal ventral axon guidanceGO:003356330.031
cellular nitrogen compound catabolic processGO:00442702800.031
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
positive regulation of nucleotide metabolic processGO:00459811140.030
response to organonitrogen compoundGO:00102432460.030
regulation of hydrolase activityGO:00513362460.029
gtp metabolic processGO:00460391440.029
innate immune responseGO:00450871570.029
cellular chemical homeostasisGO:00550822150.029
meiotic cell cycleGO:00513211220.029
regulation of vesicle mediated transportGO:00606271390.029
peptidyl tyrosine phosphorylationGO:00181081430.029
regulation of protein localizationGO:00328802310.029
retrograde transport endosome to golgiGO:004214720.029
organelle assemblyGO:00709251770.028
g protein coupled receptor signaling pathwayGO:00071862430.028
purine ribonucleoside catabolic processGO:00461302050.028
positive regulation of nervous system developmentGO:00519622210.028
regulation of cell migrationGO:00303342190.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
activation of immune responseGO:00022531380.027
purine nucleotide catabolic processGO:00061952110.027
response to organic cyclic compoundGO:00140701980.027
protein polymerizationGO:0051258570.027
regulation of mapk cascadeGO:00434082480.027
regulation of lamellipodium assemblyGO:001059130.027
sequestering of metal ionGO:0051238190.027
protein ubiquitinationGO:00165671710.027
digestive tract developmentGO:00485651900.027
cation homeostasisGO:00550802120.026
response to lipopolysaccharideGO:00324961280.026
male gamete generationGO:00482322850.026
microtubule based processGO:00070172360.026
neuron deathGO:00709971540.026
meiotic nuclear divisionGO:00071261150.026
regulation of actin cytoskeleton organizationGO:0032956840.026
positive regulation of hydrolase activityGO:00513451480.026
regulation of actin nucleationGO:005112540.026
regulation of protein transportGO:00512231630.026
regulation of ras protein signal transductionGO:00465781140.026
response to molecule of bacterial originGO:00022371430.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
compound eye developmentGO:004874910.025
purine nucleoside triphosphate metabolic processGO:00091442260.025
cation transmembrane transportGO:00986552660.025
regulation of secretionGO:00510462740.025
cell adhesionGO:00071553290.025
dna metabolic processGO:00062593030.025
transmembrane transportGO:00550854120.024
inorganic cation transmembrane transportGO:00986622070.024
peptidyl tyrosine modificationGO:00182121450.024
cellular lipid metabolic processGO:00442553230.024
regulation of intracellular transportGO:00323861590.024
leukocyte differentiationGO:00025213420.024
cellular response to growth factor stimulusGO:00713631970.024
maintenance of locationGO:0051235890.024
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.024
divalent metal ion transportGO:00708381720.024
neuron apoptotic processGO:00514021420.023
regulation of cellular component biogenesisGO:00440871810.023
central nervous system neuron differentiationGO:00219531620.023
arp2 3 complex mediated actin nucleationGO:003431430.023
positive regulation of programmed cell deathGO:00430682180.023
regulation of purine nucleotide catabolic processGO:00331211220.023
nucleocytoplasmic transportGO:00069131390.023
spermatogenesisGO:00072832840.023
axonogenesisGO:00074092740.023
purine ribonucleotide catabolic processGO:00091542080.023
sequestering of calcium ionGO:0051208180.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.023
intracellular protein transportGO:00068862040.023
dendrite developmentGO:00163581150.023
locomotory behaviorGO:00076261950.023
negative regulation of cell proliferationGO:00082852960.022
cellular response to hormone stimulusGO:00328701500.022
regulation of cell cycle processGO:00105641600.022
positive regulation of ras gtpase activityGO:0032320650.022
macromolecule methylationGO:00434141200.022
negative regulation of organelle organizationGO:0010639900.022
regulation of homeostatic processGO:00328441820.022
endomembrane system organizationGO:00102561470.022
myeloid cell differentiationGO:00300992330.022
nitrogen compound transportGO:00717052710.022
actin polymerization or depolymerizationGO:0008154540.022
regulation of inflammatory responseGO:00507271470.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
immune response regulating signaling pathwayGO:00027641250.021
positive regulation of cell deathGO:00109422240.021
activation of adenylate cyclase activityGO:000719040.021
positive regulation of protein kinase activityGO:00458601440.021
nuclear transportGO:00511691390.021
negative regulation of intracellular signal transductionGO:19025321670.021
regulation of cytoskeleton organizationGO:00514931220.021
guanosine containing compound catabolic processGO:19010691440.021
glycosyl compound catabolic processGO:19016582060.021
membrane organizationGO:00610242450.021
divalent inorganic cation transportGO:00725111780.021
carbohydrate metabolic processGO:00059752300.021
regulation of cellular catabolic processGO:00313292420.021
t cell activationGO:00421102890.021
peptidyl serine modificationGO:0018209830.021
regulation of secretion by cellGO:19035302490.021
golgi to endosome transportGO:000689530.021
photoreceptor cell morphogenesisGO:000859430.021
negative regulation of phosphorus metabolic processGO:00105631840.021
regulation of voltage gated calcium channel activityGO:190138540.020
regulation of gtp catabolic processGO:00331241130.020
cellular response to organonitrogen compoundGO:00714171450.020
chemotaxisGO:00069352470.020
endocytosisGO:00068971680.020
regulation of cytokine productionGO:00018172660.020
positive regulation of cytokine productionGO:00018191740.020
regulation of establishment of protein localizationGO:00702011810.020
methylationGO:00322591340.020
regulation of system processGO:00440572000.020
circulatory system processGO:00030131970.020
peptidyl serine phosphorylationGO:0018105740.020
ameboidal type cell migrationGO:00016671280.019
regulation of apoptotic signaling pathwayGO:20012331970.019
positive regulation of dna templated transcription elongationGO:003278620.019
negative regulation of immune system processGO:00026832090.019
regulation of hormone levelsGO:00108172110.019
positive regulation of gtp catabolic processGO:0033126850.019
homeostasis of number of cellsGO:00488722100.019
regulation of protein complex assemblyGO:0043254830.019
nuclear divisionGO:00002801580.019
regulation of cell adhesionGO:00301551540.019
leukocyte mediated immunityGO:00024431740.019
negative regulation of phosphate metabolic processGO:00459361840.019
negative regulation of neuron deathGO:1901215980.019
cellular ion homeostasisGO:00068731650.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
regulation of nucleotide catabolic processGO:00308111220.019
organophosphate biosynthetic processGO:00904071220.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
canonical wnt signaling pathwayGO:00600701300.018
cell substrate adhesionGO:00315891300.018
positive regulation of gtpase activityGO:0043547850.018
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.018
regulation of exocytosisGO:0017157610.018
regulation of anatomical structure sizeGO:00900661780.018
digestive system developmentGO:00551232000.018
multicellular organismal signalingGO:0035637910.018
regulation of leukocyte differentiationGO:19021051590.018
morphogenesis of embryonic epitheliumGO:00163311590.018
peptidyl threonine phosphorylationGO:0018107310.018
regulation of protein serine threonine kinase activityGO:00719001570.018
metal ion homeostasisGO:00550651890.018
regulation of ras gtpase activityGO:0032318880.018
post embryonic retina morphogenesis in camera type eyeGO:006006030.018
regulation of nucleoside metabolic processGO:00091181300.018
wnt signaling pathwayGO:00160551880.017
circadian rhythmGO:00076231140.017
anatomical structure homeostasisGO:00602491450.017
negative regulation of protein metabolic processGO:00512482820.017
ubiquitin dependent protein catabolic processGO:00065111290.017
gonad developmentGO:00084061410.017
response to peptideGO:19016521360.017
positive regulation of transferase activityGO:00513471670.017
engulfment of apoptotic cellGO:004365230.017
regulation of interleukin 8 productionGO:003267730.017
positive regulation of protein export from nucleusGO:004682740.017
learning or memoryGO:00076111480.017
calcium ion homeostasisGO:00550741270.017
t cell differentiation in thymusGO:0033077770.017
inflammatory responseGO:00069542440.017
camera type eye developmentGO:00430102660.017
glucose homeostasisGO:00425931280.017
attachment of spindle microtubules to kinetochoreGO:000860840.017
cell fate commitmentGO:00451652100.017
gland developmentGO:00487323300.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
positive regulation of lymphocyte activationGO:00512511400.017
multicellular organism growthGO:00352641610.017
macromolecule catabolic processGO:00090572810.017
organic hydroxy compound metabolic processGO:19016152030.017
mitotic cell cycle processGO:19030471590.016
primary neural tube formationGO:0014020950.016
protein targetingGO:00066051430.016
protein localization to organelleGO:00333651850.016
regulation of cellular response to growth factor stimulusGO:0090287820.016
sensory perceptionGO:00076002450.016
skeletal muscle organ developmentGO:00605381630.016
regulation of cellular component sizeGO:00325351210.016
positive regulation of cell motilityGO:20001471160.016
gonad morphogenesisGO:003526210.016
epithelial cell developmentGO:00020641590.016
chromatin modificationGO:00165681870.016
blood circulationGO:00080151950.016
regulation of cell divisionGO:0051302760.016
actin filament based movementGO:0030048230.016
regulation of neuron apoptotic processGO:00435231220.016
histone modificationGO:00165701590.016
positive regulation of mapk cascadeGO:00434101700.015
regulation of neuron differentiationGO:00456642810.015
positive regulation of cell migrationGO:00303351090.015
regulation of map kinase activityGO:00434051200.015
regulation of cell substrate adhesionGO:0010810730.015
synaptic transmissionGO:00072683290.015
establishment of organelle localizationGO:00516561220.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
cognitionGO:00508901490.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of response to woundingGO:19030341890.015
positive regulation of nucleoside metabolic processGO:0045979910.015
guanosine containing compound metabolic processGO:19010681440.015
regulation of neuron projection developmentGO:00109751690.015
oocyte constructionGO:000730820.015
regulation of peptidyl tyrosine phosphorylationGO:0050730930.015
divalent inorganic cation homeostasisGO:00725071380.015
protein maturationGO:00516041760.015
regulation of transpositionGO:001052820.015
positive regulation of nucleotide catabolic processGO:0030813880.015
asymmetric stem cell divisionGO:009872230.015
stem cell developmentGO:00488642190.015
positive regulation of cellular component biogenesisGO:0044089940.015
positive regulation of kinase activityGO:00336741550.015
negative regulation of cellular protein metabolic processGO:00322692470.015
cytokine productionGO:00018163190.014
blood vessel morphogenesisGO:00485142850.014
cell divisionGO:00513011200.014
regulation of actin filament polymerizationGO:0030833380.014
protein import into nucleusGO:0006606950.014
peptidyl threonine modificationGO:0018210310.014
actin filament polymerizationGO:0030041440.014
developmental maturationGO:00217001930.014
purine nucleoside catabolic processGO:00061522050.014
response to light stimulusGO:00094161350.014
tube formationGO:00351481400.014
cellular component assembly involved in morphogenesisGO:00109271390.014
protein localization to nucleusGO:00345041210.014
positive regulation of cell projection organizationGO:0031346950.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.014
covalent chromatin modificationGO:00165691630.014
synapse assemblyGO:0007416560.014
positive regulation of secretionGO:00510471300.014
negative regulation of cell motilityGO:2000146610.014
carbohydrate homeostasisGO:00335001280.014
dephosphorylationGO:00163111290.014
cytokine mediated signaling pathwayGO:00192211150.014
dendritic spine developmentGO:0060996300.014
activation of mapkkk activityGO:000018510.014
actin filament organizationGO:00070151130.014
skin developmentGO:00435882200.014
synapse organizationGO:00508081250.014
lymphocyte differentiationGO:00300982420.014
spermatid differentiationGO:00485151150.014
nucleotide biosynthetic processGO:0009165780.014
negative regulation of neuron apoptotic processGO:0043524920.014
striated muscle tissue developmentGO:00147062930.014
purine nucleotide biosynthetic processGO:0006164650.014
regulation of circadian sleep wake cycle sleepGO:004518730.014
negative regulation of protein phosphorylationGO:00019331260.014
muscle cell differentiationGO:00426922610.013
epithelial tube formationGO:00721751300.013
regulation of proteolysisGO:00301621640.013
calcium ion transportGO:00068161590.013
response to growth factorGO:00708481980.013
response to oxygen levelsGO:0070482620.013
positive regulation of cellular catabolic processGO:00313311480.013
forebrain developmentGO:00309003020.013
regulation of ion transportGO:00432692150.013
ossificationGO:00015032160.013
spermatid developmentGO:00072861080.013
fat cell differentiationGO:00454441600.013
myeloid leukocyte differentiationGO:00025731190.013
protein catabolic processGO:00301632210.013
negative regulation of protein complex disassemblyGO:0043242220.013
positive regulation of neuron differentiationGO:00456661410.013
sensory system developmentGO:004888030.013
establishment of protein localization to organelleGO:00725941180.013
small molecule biosynthetic processGO:00442831320.013
muscle tissue developmentGO:00605373080.013
response to peptide hormoneGO:00434341270.013
multicellular organismal homeostasisGO:00488711640.013
regulation of nucleotide metabolic processGO:00061401690.013
inorganic ion transmembrane transportGO:00986602340.013
negative regulation of protein modification processGO:00314001630.013
epidermis developmentGO:00085441870.013
cellular response to dna damage stimulusGO:00069742070.013
chromatin organizationGO:00063252060.013
t cell proliferationGO:00420981200.013
regulation of cell growthGO:0001558910.012
organelle localizationGO:00516401790.012
meiotic cell cycle processGO:1903046770.012
stem cell differentiationGO:00488632680.012
negative regulation of cell migrationGO:0030336590.012
single organism cell adhesionGO:00986021560.012
localization within membraneGO:005166840.012
cardiac muscle contractionGO:0060048320.012
exocytosisGO:00068871210.012
regulation of transmembrane transportGO:00347621280.012
regulation of actin filament lengthGO:0030832450.012
phospholipid metabolic processGO:0006644870.012
response to radiationGO:00093141650.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
cellular response to lipidGO:00713961450.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
protein importGO:00170381010.012
gastrulationGO:00073691160.012
response to insulinGO:00328681000.012
epithelial tube morphogenesisGO:00605623030.012
fertilizationGO:00095661270.012
cellular response to insulin stimulusGO:0032869780.012
cellular carbohydrate metabolic processGO:00442621190.012
myosin filament organizationGO:003103330.012
inter male aggressive behaviorGO:000212130.012
negative regulation of kinase activityGO:0033673810.012
transmission of nerve impulseGO:0019226760.012
single organism nuclear importGO:1902593950.012
regulation of cytoplasmic transportGO:19036491120.012
positive regulation of cell adhesionGO:0045785800.012
germ cell developmentGO:00072811850.012
neural tube formationGO:00018411080.012
positive regulation of organelle organizationGO:00106381280.012
negative regulation of cell cycleGO:00457861230.012
regulation of protein localization to nucleusGO:1900180600.011
negative regulation of transferase activityGO:0051348850.011
regulation of lipid metabolic processGO:00192161180.011
cellular response to peptideGO:1901653920.011
leukocyte proliferationGO:00706611720.011
rhythmic processGO:00485111740.011
immune response activating signal transductionGO:00027571160.011
heart processGO:0003015940.011
leukocyte activation involved in immune responseGO:00023661260.011
regulation of cellular response to stressGO:00801351590.011
t cell differentiationGO:00302171740.011
mitotic cell cycleGO:00002781950.011
regulation of nuclear divisionGO:0051783560.011
substantia nigra developmentGO:002176220.011
negative regulation of response to woundingGO:1903035770.011
cytosolic calcium ion homeostasisGO:0051480700.011
cellular macromolecule catabolic processGO:00442652060.011
positive regulation of lamellipodium assemblyGO:001059220.011
lymphocyte mediated immunityGO:00024491390.011
skeletal system developmentGO:00015013560.011
cellular metal ion homeostasisGO:00068751510.011
regulation of muscle system processGO:0090257800.011
digestive tract morphogenesisGO:00485461470.011
regulation of vasculature developmentGO:1901342880.011
positive regulation of cell activationGO:00508671580.011
regulation of actin filament based processGO:0032970990.011
modification dependent protein catabolic processGO:00199411330.011
response to extracellular stimulusGO:00099911270.011
anion transportGO:00068201770.011
oxidation reduction processGO:00551143420.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
cellular response to interleukin 15GO:007135020.011
cell activation involved in immune responseGO:00022631260.011
positive regulation of apoptotic processGO:00430652170.011
regulation of metal ion transportGO:00109591060.011
neural tube closureGO:0001843900.011
positive regulation of monocyte chemotaxisGO:009002620.011
sulfur compound metabolic processGO:00067901000.011
embryonic epithelial tube formationGO:00018381300.011
regulation of neuron deathGO:19012141340.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
nucleoside phosphate biosynthetic processGO:1901293790.011
respiratory system developmentGO:00605411900.011
peptide hormone secretionGO:00300721090.011
response to nutrient levelsGO:00316671090.011
lymphocyte proliferationGO:00466511640.011
tissue homeostasisGO:00018941150.011
i kappab kinase nf kappab signalingGO:0007249850.011
regulation of arp2 3 complex mediated actin nucleationGO:003431510.011
amide transportGO:00428861380.011
sensory organ morphogenesisGO:00905962420.011
connective tissue developmentGO:00614481790.010
nuclear importGO:0051170950.010
leukocyte migrationGO:00509001240.010
phagocytosisGO:0006909660.010
ear morphogenesisGO:00424711180.010
regulation of rho gtpase activityGO:0032319580.010
ear developmentGO:00435832000.010
regulation of synapse assemblyGO:0051963290.010
peptide secretionGO:00027901140.010
regulation of circadian sleep wake cycleGO:004274930.010
positive regulation of leukocyte proliferationGO:0070665730.010
negative regulation of cytoskeleton organizationGO:0051494360.010
rac protein signal transductionGO:0016601130.010
establishment or maintenance of cell polarityGO:0007163860.010
muscle system processGO:00030121410.010
regulation of endopeptidase activityGO:0052548890.010
mesodermal cell migrationGO:000807840.010
heart contractionGO:0060047930.010
regulation of membrane potentialGO:00423911920.010
neuronal action potentialGO:0019228540.010
microtubule cytoskeleton organizationGO:00002261570.010
positive regulation of cytoskeleton organizationGO:0051495490.010
cellular response to molecule of bacterial originGO:0071219830.010
dna repairGO:00062811070.010
secretory granule organizationGO:0033363200.010
alcohol metabolic processGO:00060661160.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.010
regulation of leukocyte proliferationGO:00706631210.010

Cdc42se2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone diseaseDOID:008000100.015
disease of anatomical entityDOID:700.015
musculoskeletal system diseaseDOID:1700.015
connective tissue diseaseDOID:6500.015
nervous system diseaseDOID:86300.015
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.011
organ system cancerDOID:005068600.011
disease of metabolismDOID:001466700.010