IMP: Integrative Multi-species Prediction

Mus musculus

84 known processes

Nefm

neurofilament, medium polypeptide

(Aliases: NF-M,NF165,Nfm,Nef3,NF160)

Ensembl: ENSMUSG00000022054
Entrez: 18040
UniProtKB: P08553

Process Predictions
Disease Predictions

Nefm biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of schwann cell proliferation	GO:0010625	1	0.925	Mouse
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.877	Mouse
intermediate filament bundle assembly	GO:0045110	3	0.873
schwann cell proliferation	GO:0014010	2	0.823	Mouse
neurofilament cytoskeleton organization	GO:0060052	10	0.790
regulation of neuron projection development	GO:0010975	169	0.784
locomotory behavior	GO:0007626	195	0.723
synaptic transmission	GO:0007268	329	0.708	Mouse
camera type eye development	GO:0043010	266	0.707	Mouse
axonogenesis	GO:0007409	274	0.687
axon cargo transport	GO:0008088	33	0.676
regulation of schwann cell proliferation	GO:0010624	2	0.670	Mouse
gliogenesis	GO:0042063	141	0.634	Mouse
action potential	GO:0001508	78	0.612
axon guidance	GO:0007411	141	0.586
neuronal action potential	GO:0019228	54	0.579
regulation of membrane potential	GO:0042391	192	0.562
regulation of anatomical structure size	GO:0090066	178	0.524
regulation of gliogenesis	GO:0014013	50	0.524	Mouse
intermediate filament organization	GO:0045109	15	0.522
positive regulation of nervous system development	GO:0051962	221	0.487	Mouse
transmission of nerve impulse	GO:0019226	76	0.471
glial cell differentiation	GO:0010001	131	0.449	Mouse
circulatory system process	GO:0003013	197	0.448
multicellular organismal signaling	GO:0035637	91	0.442
regulation of neuron differentiation	GO:0045664	281	0.408
neuromuscular process	GO:0050905	99	0.396	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.393
adult locomotory behavior	GO:0008344	91	0.386
intermediate filament cytoskeleton organization	GO:0045104	26	0.371
regulation of ion transport	GO:0043269	215	0.370
neuron projection guidance	GO:0097485	141	0.370
regulation of cellular component size	GO:0032535	121	0.367
regulation of synaptic plasticity	GO:0048167	87	0.365	Mouse
regulation of axon diameter	GO:0031133	6	0.356
adult behavior	GO:0030534	135	0.356
microtubule cytoskeleton organization	GO:0000226	157	0.352
neuron projection extension	GO:1990138	64	0.345
inorganic ion transmembrane transport	GO:0098660	234	0.345
transmembrane transport	GO:0055085	412	0.328
synaptic vesicle priming	GO:0016082	8	0.308
developmental maturation	GO:0021700	193	0.303
glial cell development	GO:0021782	54	0.288	Mouse
positive regulation of cell development	GO:0010720	237	0.270	Mouse
microtubule based movement	GO:0007018	84	0.268
positive regulation of neuron projection development	GO:0010976	79	0.263	Mouse
regulation of cell projection organization	GO:0031344	206	0.262
positive regulation of neuron differentiation	GO:0045666	141	0.261	Mouse
organelle localization	GO:0051640	179	0.255
chemotaxis	GO:0006935	247	0.248
cell recognition	GO:0008037	83	0.245
regulation of neurotransmitter uptake	GO:0051580	6	0.240	Mouse
striated muscle tissue development	GO:0014706	293	0.239
epidermis development	GO:0008544	187	0.233
regulation of system process	GO:0044057	200	0.231
pole plasm assembly	GO:0007315	2	0.228
negative regulation of neuron projection development	GO:0010977	50	0.224	Mouse
epithelial cell development	GO:0002064	159	0.219	Mouse
sodium ion transport	GO:0006814	73	0.217
microtubule based process	GO:0007017	236	0.216
myelination	GO:0042552	74	0.215
ensheathment of neurons	GO:0007272	76	0.215
ion transmembrane transport	GO:0034220	361	0.215
regulation of cell projection size	GO:0032536	6	0.213
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.211	Mouse
neuron migration	GO:0001764	122	0.207
intermediate filament based process	GO:0045103	27	0.205
learning	GO:0007612	98	0.202
regulation of neuron apoptotic process	GO:0043523	122	0.199	Mouse
neuron apoptotic process	GO:0051402	142	0.199	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.188	Mouse
macromolecular complex disassembly	GO:0032984	43	0.182
cell maturation	GO:0048469	127	0.179
axon ensheathment	GO:0008366	76	0.168
cellular protein complex disassembly	GO:0043624	36	0.164
regulation of ion transmembrane transport	GO:0034765	119	0.163
ear development	GO:0043583	200	0.162
regulation of neuron death	GO:1901214	134	0.161	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.157
actin mediated cell contraction	GO:0070252	15	0.154
intracellular protein transport	GO:0006886	204	0.154
axonal fasciculation	GO:0007413	15	0.153
cytoskeleton dependent intracellular transport	GO:0030705	50	0.153
regulation of exocytosis	GO:0017157	61	0.149
membrane organization	GO:0061024	245	0.145
negative regulation of molecular function	GO:0044092	258	0.143
oocyte anterior posterior axis specification	GO:0007314	2	0.139
sa node cell action potential	GO:0086015	4	0.139
multi organism behavior	GO:0051705	62	0.138
exocytosis	GO:0006887	121	0.138
adult walking behavior	GO:0007628	41	0.136
membrane depolarization	GO:0051899	64	0.134
microtubule polymerization or depolymerization	GO:0031109	26	0.134
sensory perception	GO:0007600	245	0.132
axon regeneration	GO:0031103	12	0.130	Mouse
regulation of muscle system process	GO:0090257	80	0.127
regulation of muscle contraction	GO:0006937	49	0.125
long term synaptic potentiation	GO:0060291	25	0.123	Mouse
neurotransmitter uptake	GO:0001504	14	0.123	Mouse
cation transport	GO:0006812	399	0.123
cardiac muscle contraction	GO:0060048	32	0.122
positive regulation of ion transport	GO:0043270	65	0.119
rhythmic process	GO:0048511	174	0.117
oocyte construction	GO:0007308	2	0.117
neuron projection regeneration	GO:0031102	14	0.117	Mouse
peripheral nervous system neuron development	GO:0048935	9	0.116	Mouse
regulation of kinase activity	GO:0043549	249	0.115
synaptic vesicle localization	GO:0097479	59	0.115
regulation of secretion by cell	GO:1903530	249	0.114
muscle contraction	GO:0006936	101	0.114
regulation of neurotransmitter transport	GO:0051588	35	0.114	Mouse
negative regulation of protein depolymerization	GO:1901880	21	0.112
regulation of transmembrane transport	GO:0034762	128	0.112
neurotransmitter secretion	GO:0007269	62	0.112
cellular protein complex assembly	GO:0043623	116	0.111
cerebral cortex cell migration	GO:0021795	44	0.111
protein complex disassembly	GO:0043241	40	0.110
telencephalon cell migration	GO:0022029	55	0.109
inorganic cation transmembrane transport	GO:0098662	207	0.106
cell growth	GO:0016049	130	0.105
astrocyte differentiation	GO:0048708	43	0.105	Mouse
lens development in camera type eye	GO:0002088	62	0.105	Mouse
oxidation reduction process	GO:0055114	342	0.105
detection of abiotic stimulus	GO:0009582	60	0.103
forebrain cell migration	GO:0021885	58	0.103
regulation of striated muscle contraction	GO:0006942	25	0.102
cation transmembrane transport	GO:0098655	266	0.102
positive regulation of cell death	GO:0010942	224	0.101
oocyte axis specification	GO:0007309	2	0.098
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.098
cell type specific apoptotic process	GO:0097285	268	0.097	Mouse
molting cycle	GO:0042303	90	0.096
regulation of purine nucleotide metabolic process	GO:1900542	169	0.095
protein depolymerization	GO:0051261	34	0.093
establishment of synaptic vesicle localization	GO:0097480	57	0.093
negative regulation of intracellular signal transduction	GO:1902532	167	0.093
fertilization	GO:0009566	127	0.092
organelle assembly	GO:0070925	177	0.090
neuromuscular process controlling balance	GO:0050885	59	0.089	Mouse
regulation of neurotransmitter levels	GO:0001505	87	0.088	Mouse
ribonucleoside catabolic process	GO:0042454	206	0.087
synaptic vesicle transport	GO:0048489	57	0.086
response to light stimulus	GO:0009416	135	0.086
regulation of blood circulation	GO:1903522	93	0.086
blood circulation	GO:0008015	195	0.086
vesicle localization	GO:0051648	86	0.086
negative regulation of cell development	GO:0010721	169	0.086	Mouse
negative regulation of neuron differentiation	GO:0045665	101	0.084	Mouse
asymmetric neuroblast division	GO:0055059	1	0.084
protein polymerization	GO:0051258	57	0.082
mechanoreceptor differentiation	GO:0042490	67	0.081
purine containing compound metabolic process	GO:0072521	311	0.081
hindbrain development	GO:0030902	128	0.080
regulation of mapk cascade	GO:0043408	248	0.080
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.079
response to organonitrogen compound	GO:0010243	246	0.079
detection of stimulus	GO:0051606	84	0.079
auditory receptor cell fate determination	GO:0042668	3	0.077
oligodendrocyte development	GO:0014003	20	0.077
striated muscle contraction	GO:0006941	45	0.076
telencephalon development	GO:0021537	186	0.076
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.076	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.076
protein processing	GO:0016485	163	0.075
negative regulation of neuron death	GO:1901215	98	0.075	Mouse
muscle system process	GO:0003012	141	0.075
oligodendrocyte differentiation	GO:0048709	53	0.073
organic cyclic compound catabolic process	GO:1901361	295	0.073
purine nucleotide metabolic process	GO:0006163	302	0.073
ribose phosphate metabolic process	GO:0019693	291	0.073
neuroblast proliferation	GO:0007405	49	0.072
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.072
glycosyl compound metabolic process	GO:1901657	246	0.072
regulation of secretion	GO:0051046	274	0.072
regulation of vasculature development	GO:1901342	88	0.071
glucose metabolic process	GO:0006006	92	0.071
single fertilization	GO:0007338	82	0.070
regulation of axon extension	GO:0030516	43	0.069
regulation of microtubule polymerization or depolymerization	GO:0031110	20	0.069
regulation of intracellular transport	GO:0032386	159	0.069
urogenital system development	GO:0001655	261	0.068
regionalization	GO:0003002	337	0.068
negative regulation of cytoskeleton organization	GO:0051494	36	0.067
developmental growth involved in morphogenesis	GO:0060560	138	0.066
muscle tissue development	GO:0060537	308	0.066
neuron recognition	GO:0008038	25	0.066
gonad development	GO:0008406	141	0.066
purine ribonucleoside metabolic process	GO:0046128	241	0.065
actin filament based movement	GO:0030048	23	0.065
positive regulation of glial cell proliferation	GO:0060252	4	0.065	Mouse
defecation	GO:0030421	1	0.063
neuron death	GO:0070997	154	0.063	Mouse
directional locomotion	GO:0033058	3	0.062
positive regulation of high voltage gated calcium channel activity	GO:1901843	1	0.062
protein maturation	GO:0051604	176	0.062
regulation of hydrolase activity	GO:0051336	246	0.061
cell proliferation in hindbrain	GO:0021534	10	0.061
respiratory system development	GO:0060541	190	0.061
nucleoside phosphate metabolic process	GO:0006753	338	0.060
heart process	GO:0003015	94	0.060
posttranscriptional regulation of gene expression	GO:0010608	155	0.059
organophosphate catabolic process	GO:0046434	232	0.059
nuclear transport	GO:0051169	139	0.059
appendage morphogenesis	GO:0035107	149	0.059
memory	GO:0007613	58	0.058
monosaccharide metabolic process	GO:0005996	106	0.058
limb development	GO:0060173	166	0.058
intracellular mrna localization	GO:0008298	4	0.058
sensory organ morphogenesis	GO:0090596	242	0.058
regulation of metal ion transport	GO:0010959	106	0.057
regulation of cardiac muscle contraction	GO:0055117	21	0.057
purine nucleotide catabolic process	GO:0006195	211	0.056
regulation of extent of cell growth	GO:0061387	52	0.056
extracellular matrix organization	GO:0030198	147	0.056	Mouse
negative regulation of cell projection organization	GO:0031345	56	0.056	Mouse
carbohydrate metabolic process	GO:0005975	230	0.056
regulation of body fluid levels	GO:0050878	162	0.056
purine nucleoside metabolic process	GO:0042278	241	0.055
carboxylic acid transport	GO:0046942	100	0.055
appendage development	GO:0048736	166	0.055
calcium ion transport	GO:0006816	159	0.054
regulation of astrocyte differentiation	GO:0048710	20	0.054
regulation of cell growth	GO:0001558	91	0.054
reproductive behavior	GO:0019098	32	0.054
cellular response to peptide hormone stimulus	GO:0071375	92	0.054
regulation of postsynaptic membrane potential	GO:0060078	48	0.053
negative regulation of nervous system development	GO:0051961	156	0.053	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.053
hexose metabolic process	GO:0019318	98	0.053
extracellular structure organization	GO:0043062	148	0.053	Mouse
sperm motility	GO:0030317	47	0.053
regulation of blood pressure	GO:0008217	93	0.053
neurotransmitter transport	GO:0006836	76	0.053	Mouse
myelination in peripheral nervous system	GO:0022011	19	0.052
response to radiation	GO:0009314	165	0.052
regulation of glial cell differentiation	GO:0045685	41	0.052
immune effector process	GO:0002252	321	0.052
apoptotic signaling pathway	GO:0097190	306	0.052
cell fate commitment	GO:0045165	210	0.052
ribonucleotide catabolic process	GO:0009261	208	0.052
cellular lipid metabolic process	GO:0044255	323	0.052
male genitalia morphogenesis	GO:0048808	4	0.052
cation homeostasis	GO:0055080	212	0.051
cardiac muscle cell contraction	GO:0086003	7	0.051
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.051
skeletal system development	GO:0001501	356	0.050
cerebral cortex development	GO:0021987	86	0.050
negative regulation of microtubule polymerization or depolymerization	GO:0031111	15	0.050
microtubule based transport	GO:0010970	50	0.050
negative regulation of phosphorylation	GO:0042326	166	0.050
cell cell signaling involved in lung development	GO:0060495	1	0.049
bronchiole development	GO:0060435	3	0.048
germ cell development	GO:0007281	185	0.048
response to organic cyclic compound	GO:0014070	198	0.048
glycosyl compound catabolic process	GO:1901658	206	0.048
smad protein signal transduction	GO:0060395	21	0.048	Mouse
dendrite development	GO:0016358	115	0.048
reflex	GO:0060004	22	0.047
nitrogen compound transport	GO:0071705	271	0.047
developmental cell growth	GO:0048588	84	0.047
stem cell maintenance	GO:0019827	130	0.047
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.047
mitochondrion organization	GO:0007005	134	0.047
regulation of organelle organization	GO:0033043	289	0.046
nerve development	GO:0021675	67	0.046
neural precursor cell proliferation	GO:0061351	121	0.046
regulation of neurotransmitter secretion	GO:0046928	29	0.046
positive regulation of transferase activity	GO:0051347	167	0.046
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.046
mitochondrion transport along microtubule	GO:0047497	3	0.046
regulation of cellular ketone metabolic process	GO:0010565	66	0.046
organonitrogen compound catabolic process	GO:1901565	264	0.046
negative regulation of protein metabolic process	GO:0051248	282	0.046
nucleoside phosphate catabolic process	GO:1901292	222	0.045
sensory system development	GO:0048880	3	0.045
purine ribonucleotide metabolic process	GO:0009150	290	0.045
positive regulation of protein phosphorylation	GO:0001934	242	0.045
negative regulation of phosphate metabolic process	GO:0045936	184	0.045
nucleoside catabolic process	GO:0009164	206	0.045
glycerolipid metabolic process	GO:0046486	122	0.044
negative regulation of protein complex disassembly	GO:0043242	22	0.044
rna splicing	GO:0008380	54	0.044
positive regulation of mapk cascade	GO:0043410	170	0.044
neuron neuron synaptic transmission	GO:0007270	69	0.044
asymmetric stem cell division	GO:0098722	3	0.044
divalent metal ion transport	GO:0070838	172	0.044
development of primary sexual characteristics	GO:0045137	143	0.043
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.043
lymphocyte differentiation	GO:0030098	242	0.042
calcium ion dependent exocytosis	GO:0017156	35	0.042
muscle cell differentiation	GO:0042692	261	0.042
regulation of voltage gated calcium channel activity	GO:1901385	4	0.042
t cell activation	GO:0042110	289	0.042
canonical wnt signaling pathway	GO:0060070	130	0.042
regulation of defense response	GO:0031347	233	0.042
stem cell proliferation	GO:0072089	117	0.042
anion transport	GO:0006820	177	0.042
positive regulation of sodium ion transport	GO:0010765	13	0.042
positive regulation of apoptotic process	GO:0043065	217	0.041
endocrine system development	GO:0035270	98	0.041
male sex differentiation	GO:0046661	109	0.040
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.040
substantia nigra development	GO:0021762	2	0.040
establishment of glial blood brain barrier	GO:0060857	2	0.040
negative regulation of organelle organization	GO:0010639	90	0.040
organophosphate biosynthetic process	GO:0090407	122	0.040
spermatogenesis	GO:0007283	284	0.039
positive regulation of growth	GO:0045927	104	0.039
lateral line system development	GO:0048925	1	0.039
nuclear import	GO:0051170	95	0.039
response to peptide hormone	GO:0043434	127	0.039
heart contraction	GO:0060047	93	0.039
regulation of cell size	GO:0008361	72	0.038
carbohydrate derivative catabolic process	GO:1901136	231	0.038
inner ear receptor cell differentiation	GO:0060113	61	0.038
regulation of systemic arterial blood pressure	GO:0003073	61	0.037
translation	GO:0006412	93	0.037
inflammatory response	GO:0006954	244	0.037
forebrain generation of neurons	GO:0021872	63	0.037
protein localization to nucleus	GO:0034504	121	0.037
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.037
cerebellum development	GO:0021549	77	0.037
mitochondrial transport	GO:0006839	36	0.037
auditory receptor cell differentiation	GO:0042491	37	0.037
potassium ion homeostasis	GO:0055075	4	0.037
lung development	GO:0030324	164	0.037
regulation of nucleotide metabolic process	GO:0006140	169	0.037
spleen development	GO:0048536	39	0.036
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.036
epidermis morphogenesis	GO:0048730	33	0.036
establishment of mitochondrion localization	GO:0051654	4	0.036
peripheral nervous system axon regeneration	GO:0014012	2	0.036	Mouse
hair follicle morphogenesis	GO:0031069	29	0.036
transdifferentiation	GO:0060290	1	0.036
heterocycle catabolic process	GO:0046700	280	0.036
hematopoietic progenitor cell differentiation	GO:0002244	143	0.036
sensory perception of sound	GO:0007605	97	0.036
respiratory tube development	GO:0030323	167	0.036
rna processing	GO:0006396	105	0.035
purine ribonucleotide catabolic process	GO:0009154	208	0.035
nucleotide catabolic process	GO:0009166	217	0.035
learning or memory	GO:0007611	148	0.035
embryonic limb morphogenesis	GO:0030326	126	0.035
hindbrain maturation	GO:0021578	6	0.035
establishment of vesicle localization	GO:0051650	81	0.035
regulation of dendritic spine morphogenesis	GO:0061001	17	0.035
acylglycerol metabolic process	GO:0006639	55	0.035
mrna splicing via spliceosome	GO:0000398	43	0.035
kidney development	GO:0001822	213	0.035
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.035
motor neuron migration	GO:0097475	4	0.035
white fat cell proliferation	GO:0070343	2	0.034
vesicle organization	GO:0016050	60	0.034
axon target recognition	GO:0007412	4	0.034
intracellular distribution of mitochondria	GO:0048312	1	0.034
leukocyte differentiation	GO:0002521	342	0.034
calcium ion transmembrane transport	GO:0070588	85	0.034
regulation of homeostatic process	GO:0032844	182	0.034
central nervous system neuron development	GO:0021954	67	0.034
positive regulation of cell projection organization	GO:0031346	95	0.034	Mouse
hormone secretion	GO:0046879	128	0.034
central nervous system projection neuron axonogenesis	GO:0021952	21	0.034
cellular ketone metabolic process	GO:0042180	84	0.034
digestive tract development	GO:0048565	190	0.034
multi multicellular organism process	GO:0044706	109	0.034
motor neuron axon guidance	GO:0008045	26	0.034
regulation of high voltage gated calcium channel activity	GO:1901841	2	0.033
protein oligomerization	GO:0051259	67	0.033
nucleoside metabolic process	GO:0009116	246	0.033
zygotic determination of anterior posterior axis embryo	GO:0007354	3	0.033
protein catabolic process	GO:0030163	221	0.033
circadian rhythm	GO:0007623	114	0.033
negative regulation of cellular protein metabolic process	GO:0032269	247	0.033
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.032
cellular nitrogen compound catabolic process	GO:0044270	280	0.032
astrocyte development	GO:0014002	12	0.032	Mouse
skin development	GO:0043588	220	0.032
protein import	GO:0017038	101	0.032
blood vessel morphogenesis	GO:0048514	285	0.032
brain segmentation	GO:0035284	3	0.032
multicellular organism growth	GO:0035264	161	0.031
positive regulation of ion transmembrane transporter activity	GO:0032414	15	0.031
retina development in camera type eye	GO:0060041	119	0.031
divalent inorganic cation transport	GO:0072511	178	0.031
ribonucleoside metabolic process	GO:0009119	245	0.031
feeding behavior	GO:0007631	62	0.031
maintenance of presynaptic active zone structure	GO:0048790	1	0.031
regeneration	GO:0031099	38	0.031	Mouse
leukocyte mediated immunity	GO:0002443	174	0.031
cellular carbohydrate metabolic process	GO:0044262	119	0.031
phospholipid metabolic process	GO:0006644	87	0.031
developmental induction	GO:0031128	34	0.031
excretion	GO:0007588	22	0.031
multicellular organismal reproductive behavior	GO:0033057	23	0.031
regulation of protein localization	GO:0032880	231	0.030
central nervous system neuron differentiation	GO:0021953	162	0.030
positive regulation of fat cell proliferation	GO:0070346	1	0.030
stem cell differentiation	GO:0048863	268	0.030
somatotropin secreting cell development	GO:0060133	2	0.030
g protein coupled receptor signaling pathway	GO:0007186	243	0.030
regulation of nucleotide catabolic process	GO:0030811	122	0.030
embryonic appendage morphogenesis	GO:0035113	126	0.030
multi organism reproductive behavior	GO:0044705	29	0.030
kidney epithelium development	GO:0072073	121	0.030
production of molecular mediator of immune response	GO:0002440	103	0.030
cytoplasmic transport	GO:0016482	234	0.030
positive regulation of synaptic plasticity	GO:0031915	4	0.030
male gamete generation	GO:0048232	285	0.030
microtubule polymerization	GO:0046785	12	0.030
plasma membrane organization	GO:0007009	90	0.030
male courtship behavior	GO:0008049	2	0.029
determination of left right asymmetry in nervous system	GO:0035545	1	0.029
dephosphorylation	GO:0016311	129	0.029
cellular response to cytokine stimulus	GO:0071345	189	0.029
protein localization to membrane	GO:0072657	108	0.029
mating	GO:0007618	27	0.029
neuron maturation	GO:0042551	29	0.029
mating behavior sex discrimination	GO:0048047	1	0.029
establishment of organelle localization	GO:0051656	122	0.029
ectoderm formation	GO:0001705	3	0.029
regulation of protein kinase activity	GO:0045859	232	0.029
hair follicle development	GO:0001942	85	0.029
lung epithelial cell differentiation	GO:0060487	29	0.029
microtubule depolymerization	GO:0007019	15	0.029
negative regulation of transferase activity	GO:0051348	85	0.029
multicellular organismal response to stress	GO:0033555	62	0.028
regulation of purine nucleotide catabolic process	GO:0033121	122	0.028
corticotropin hormone secreting cell differentiation	GO:0060128	3	0.028
endocytosis	GO:0006897	168	0.028
synaptic transmission cholinergic	GO:0007271	7	0.028
regulation of cell migration	GO:0030334	219	0.028
regulation of circadian rhythm	GO:0042752	58	0.028
morphogenesis of a branching epithelium	GO:0061138	193	0.028
forebrain neuron differentiation	GO:0021879	52	0.028
anatomical structure homeostasis	GO:0060249	145	0.028
ras protein signal transduction	GO:0007265	77	0.028
protein targeting	GO:0006605	143	0.028
cellular component assembly involved in morphogenesis	GO:0010927	139	0.028
regulation of vesicle mediated transport	GO:0060627	139	0.028
hatching	GO:0035188	4	0.028
gland development	GO:0048732	330	0.028
vascular endothelial growth factor receptor signaling pathway	GO:0048010	24	0.028
sensory perception of mechanical stimulus	GO:0050954	107	0.027
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.027
regulation of microtubule based process	GO:0032886	52	0.027
purine ribonucleoside catabolic process	GO:0046130	205	0.027
carbohydrate derivative biosynthetic process	GO:1901137	183	0.027
innervation	GO:0060384	22	0.027
nucleotide metabolic process	GO:0009117	332	0.027
regulation of cytoskeleton organization	GO:0051493	122	0.027
negative regulation of phosphorus metabolic process	GO:0010563	184	0.027
regulation of renin secretion into blood stream	GO:1900133	4	0.027
positive regulation of secretion	GO:0051047	130	0.027
nucleocytoplasmic transport	GO:0006913	139	0.027
positive regulation of transmembrane transport	GO:0034764	29	0.027
ventricular cardiac muscle cell action potential	GO:0086005	4	0.027
lung pattern specification process	GO:0060432	1	0.027
relaxation of vascular smooth muscle	GO:0060087	7	0.027
regulation of cellular component biogenesis	GO:0044087	181	0.027
positive regulation of gliogenesis	GO:0014015	27	0.027	Mouse
male gonad development	GO:0008584	88	0.027
single organism nuclear import	GO:1902593	95	0.027
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.027
regulation of protein serine threonine kinase activity	GO:0071900	157	0.026
regulation of calcium ion transmembrane transport	GO:1903169	20	0.026
negative regulation of immune system process	GO:0002683	209	0.026
semicircular canal fusion	GO:0060879	1	0.026
hair cell differentiation	GO:0035315	40	0.026
regulation of neuronal synaptic plasticity	GO:0048168	30	0.026
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.026
regulation of microtubule depolymerization	GO:0031114	13	0.026
organic acid transport	GO:0015849	101	0.026
striated muscle cell development	GO:0055002	125	0.026
limb morphogenesis	GO:0035108	149	0.026
endomembrane system organization	GO:0010256	147	0.025
optic nerve structural organization	GO:0021633	2	0.025
lung morphogenesis	GO:0060425	50	0.025
regulation of synaptic vesicle exocytosis	GO:2000300	11	0.025
hormone metabolic process	GO:0042445	86	0.025
positive regulation of ion transmembrane transport	GO:0034767	24	0.025
regulation of white fat cell proliferation	GO:0070350	2	0.025
regulation of translation	GO:0006417	71	0.025
regulation of lymphocyte activation	GO:0051249	240	0.025
regulation of mrna metabolic process	GO:1903311	43	0.025
peripheral nervous system development	GO:0007422	53	0.025	Mouse
negative regulation of microtubule depolymerization	GO:0007026	13	0.025
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.025
regulation of sodium ion transport	GO:0002028	29	0.025
cardiac muscle cell action potential	GO:0086001	11	0.025
synaptic transmission glutamatergic	GO:0035249	36	0.025
membrane depolarization during sa node cell action potential	GO:0086046	2	0.025
cerebral cortex radial glia guided migration	GO:0021801	17	0.024
transcription from rna polymerase iii promoter	GO:0006383	3	0.024
regulation of lipid metabolic process	GO:0019216	118	0.024
response to temperature stimulus	GO:0009266	55	0.024
regulation of protein kinase b signaling	GO:0051896	56	0.024

Nefm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.210
disease of anatomical entity	DOID:7	0.210
neuropathy	DOID:870	0.055

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