Mus musculus

221 known processes

Npm1

nucleophosmin 1

(Aliases: NO38,MGC107291,MGC102162,Npm,B23)

Npm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
translationGO:0006412930.875
development of primary sexual characteristicsGO:00451371430.854
rna localizationGO:0006403230.811
oocyte anterior posterior axis specificationGO:000731420.809
body morphogenesisGO:0010171450.801
genitalia developmentGO:0048806370.741
rna processingGO:00063961050.719
germ cell developmentGO:00072811850.621
translational initiationGO:0006413240.617
oogenesisGO:0048477560.588
positive regulation of peptidase activityGO:0010952490.586
female gamete generationGO:0007292740.586
regulation of cellular component biogenesisGO:00440871810.450
rna splicingGO:0008380540.437
regulation of mitotic cell cycleGO:00073461260.424
dna repairGO:00062811070.396
gonad developmentGO:00084061410.372
positive regulation of cellular protein catabolic processGO:1903364340.369
positive regulation of proteolysisGO:0045862850.350
oocyte constructionGO:000730820.337
cellular response to cytokine stimulusGO:00713451890.296
regulation of proteolysisGO:00301621640.287
ossificationGO:00015032160.283
segmentationGO:0035282930.245
positive regulation of cellular catabolic processGO:00313311480.238
regulation of peptidase activityGO:0052547960.228
ribosomal small subunit biogenesisGO:004227440.226
mrna catabolic processGO:0006402220.203
positive regulation of hydrolase activityGO:00513451480.202
epithelial cell proliferationGO:00506731740.199
regulation of rna splicingGO:0043484370.197
organic cyclic compound catabolic processGO:19013612950.189
positive regulation of apoptotic processGO:00430652170.174
nuclear transportGO:00511691390.171
positive regulation of endopeptidase activityGO:0010950430.171
regulation of cell cycleGO:00517262810.167
organelle fissionGO:00482851700.165
nucleic acid transportGO:0050657180.159
cellular macromolecule catabolic processGO:00442652060.158
regulation of protein localizationGO:00328802310.157
mitotic cell cycle processGO:19030471590.150
positive regulation of cysteine type endopeptidase activityGO:2001056390.149
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.144
meiotic cell cycleGO:00513211220.138
regulation of cell activationGO:00508652890.125
positive regulation of mrna metabolic processGO:1903313170.125
regulation of embryonic developmentGO:0045995710.123
pole plasm assemblyGO:000731520.121
ncrna processingGO:0034470260.121
cell growthGO:00160491300.118
intracellular mrna localizationGO:000829840.113
oocyte developmentGO:0048599330.112
posttranscriptional regulation of gene expressionGO:00106081550.112
leukocyte differentiationGO:00025213420.103
striated muscle tissue developmentGO:00147062930.101
modification dependent macromolecule catabolic processGO:00436321330.098
positive regulation of programmed cell deathGO:00430682180.097
hematopoietic progenitor cell differentiationGO:00022441430.096
positive regulation of cell deathGO:00109422240.094
regulation of endopeptidase activityGO:0052548890.094
regulation of cell cycle processGO:00105641600.094
lung developmentGO:00303241640.093
cellular nitrogen compound catabolic processGO:00442702800.091
regulation of epithelial cell proliferationGO:00506781410.091
stem cell differentiationGO:00488632680.090
apoptotic signaling pathwayGO:00971903060.089
nucleocytoplasmic transportGO:00069131390.086
single fertilizationGO:0007338820.085
rrna metabolic processGO:0016072100.083
oocyte axis specificationGO:000730920.081
regulation of muscle tissue developmentGO:1901861970.081
mitotic nuclear divisionGO:0007067480.077
stem cell developmentGO:00488642190.076
regulation of cell divisionGO:0051302760.076
regulation of mrna splicing via spliceosomeGO:0048024320.074
ribosome biogenesisGO:0042254200.073
regulation of cellular catabolic processGO:00313292420.072
mitotic cell cycleGO:00002781950.068
cellular protein catabolic processGO:00442571550.068
positive regulation of rna splicingGO:0033120120.068
protein localization to nucleusGO:00345041210.068
regulation of striated muscle cell differentiationGO:0051153810.066
maternal determination of anterior posterior axis embryoGO:000835820.063
positive regulation of nucleotide metabolic processGO:00459811140.062
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.061
regulation of translationGO:0006417710.060
protein maturationGO:00516041760.060
regulation of cellular response to stressGO:00801351590.060
activation of cysteine type endopeptidase activityGO:0097202270.059
fertilizationGO:00095661270.058
oocyte differentiationGO:0009994350.058
cell divisionGO:00513011200.053
microtubule cytoskeleton organizationGO:00002261570.053
negative regulation of cellular protein metabolic processGO:00322692470.052
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.051
cell type specific apoptotic processGO:00972852680.049
blood vessel morphogenesisGO:00485142850.049
response to lipopolysaccharideGO:00324961280.049
negative regulation of growthGO:0045926990.048
nuclear transcribed mrna catabolic processGO:0000956160.048
respiratory tube developmentGO:00303231670.047
nuclear divisionGO:00002801580.047
muscle tissue developmentGO:00605373080.047
positive regulation of cell cycle phase transitionGO:1901989170.046
negative regulation of rna splicingGO:0033119120.042
multicellular organismal agingGO:0010259240.041
regulation of mrna processingGO:0050684410.041
zymogen activationGO:0031638410.040
ras protein signal transductionGO:0007265770.040
mrna metabolic processGO:0016071840.040
positive regulation of cellular component biogenesisGO:0044089940.040
maturation of ssu rrnaGO:003049010.039
regulation of cell cycle phase transitionGO:1901987770.039
digestive tract morphogenesisGO:00485461470.037
determination of left right symmetryGO:0007368800.037
positive regulation of transcription from rna polymerase i promoterGO:004594330.036
3 utr mediated mrna stabilizationGO:007093520.036
protein localization to organelleGO:00333651850.036
regulation of lymphocyte differentiationGO:00456191070.034
nuclear importGO:0051170950.034
rna catabolic processGO:0006401290.033
regulation of nucleocytoplasmic transportGO:0046822730.033
rna splicing via transesterification reactionsGO:0000375430.033
microtubule organizing center organizationGO:0031023280.033
cellular response to dna damage stimulusGO:00069742070.032
cell maturationGO:00484691270.032
camera type eye developmentGO:00430102660.031
regulation of leukocyte differentiationGO:19021051590.031
regulation of organ morphogenesisGO:20000271440.031
stem cell maintenanceGO:00198271300.031
regulation of nucleotide catabolic processGO:00308111220.030
lymphocyte differentiationGO:00300982420.030
ribonucleoprotein complex subunit organizationGO:0071826280.030
posttranscriptional gene silencing by rnaGO:0035194100.029
cellular response to lipidGO:00713961450.029
regulation of hydrolase activityGO:00513362460.029
spermatid differentiationGO:00485151150.029
lymphocyte proliferationGO:00466511640.029
heart morphogenesisGO:00030071780.029
regulation of synaptic growth at neuromuscular junctionGO:000858240.029
aromatic compound catabolic processGO:00194392860.028
cartilage developmentGO:00512161400.028
regulation of mitotic cell cycle phase transitionGO:1901990730.028
spermatid developmentGO:00072861080.027
positive regulation of mitotic cell cycleGO:0045931410.027
heterocycle catabolic processGO:00467002800.026
small gtpase mediated signal transductionGO:0007264970.025
regulation of establishment of protein localizationGO:00702011810.025
digestive system developmentGO:00551232000.025
regulation of alternative mrna splicing via spliceosomeGO:000038180.025
inflammatory responseGO:00069542440.025
glycosyl compound catabolic processGO:19016582060.024
regionalizationGO:00030023370.024
cytoplasmic transportGO:00164822340.024
angiogenesisGO:00015252010.024
positive regulation of mrna splicing via spliceosomeGO:0048026110.024
maintenance of locationGO:0051235890.024
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225480.024
regulation of cellular protein catabolic processGO:1903362610.023
regulation of lymphocyte activationGO:00512492400.023
cell chemotaxisGO:0060326810.023
negative regulation of cell growthGO:0030308440.023
myotube differentiationGO:00149021050.023
regulation of protein catabolic processGO:00421761080.022
alternative mrna splicing via spliceosomeGO:0000380120.022
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.022
positive regulation of growthGO:00459271040.021
regulation of cell growthGO:0001558910.021
negative regulation of epithelial cell proliferationGO:0050680640.021
chemotaxisGO:00069352470.020
regulation of cysteine type endopeptidase activityGO:2000116650.020
negative regulation of neuron deathGO:1901215980.020
cell cell recognitionGO:0009988440.020
establishment of organelle localizationGO:00516561220.020
epithelial tube morphogenesisGO:00605623030.020
chromatin organizationGO:00063252060.020
Mouse
regulation of mrna stabilityGO:0043488230.019
blastoderm segmentationGO:0007350130.019
positive regulation of protein phosphorylationGO:00019342420.019
molting cycleGO:0042303900.019
ribonucleotide catabolic processGO:00092612080.019
response to temperature stimulusGO:0009266550.019
digestive tract developmentGO:00485651900.019
regulation of oocyte developmentGO:006028190.019
placenta developmentGO:00018901400.019
negative regulation of immune system processGO:00026832090.019
regulation of apoptotic signaling pathwayGO:20012331970.019
regulation of reproductive processGO:2000241660.019
skeletal system developmentGO:00015013560.018
regulation of carbohydrate metabolic processGO:0006109750.018
viral gene expressionGO:001908030.018
dna packagingGO:0006323300.018
cyclic nucleotide metabolic processGO:0009187590.018
positive regulation of glycogen catabolic processGO:004581920.018
regulation of homeostatic processGO:00328441820.017
polysaccharide metabolic processGO:0005976390.017
embryonic organ morphogenesisGO:00485622760.017
response to oxygen levelsGO:0070482620.017
negative regulation of translationGO:0017148220.017
ribosomal small subunit assemblyGO:000002810.017
regulation of glycogen catabolic processGO:000598120.016
positive regulation of protein catabolic processGO:0045732600.016
response to organic cyclic compoundGO:00140701980.016
embryonic axis specificationGO:0000578300.016
ion transmembrane transportGO:00342203610.016
ribosomal large subunit biogenesisGO:004227350.016
dendrite developmentGO:00163581150.016
positive regulation of epithelial cell proliferationGO:0050679680.016
organophosphate catabolic processGO:00464342320.016
t cell activationGO:00421102890.016
wound healingGO:00420601570.015
nucleotide metabolic processGO:00091173320.015
meiotic nuclear divisionGO:00071261150.015
neural tube formationGO:00018411080.015
negative regulation of oxidative stress induced neuron deathGO:190320420.015
single organism nuclear importGO:1902593950.015
positive regulation of mrna processingGO:0050685160.015
gene silencingGO:0016458380.015
multicellular organism growthGO:00352641610.015
purine nucleoside catabolic processGO:00061522050.015
regulation of bindingGO:00510981110.015
regulation of neuron deathGO:19012141340.015
skeletal muscle organ developmentGO:00605381630.015
inorganic ion transmembrane transportGO:00986602340.015
regulation of purine nucleotide metabolic processGO:19005421690.015
negative regulation of bindingGO:0051100390.015
mesenchymal cell differentiationGO:00487621070.015
positive regulation of mitotic cell cycle phase transitionGO:1901992170.014
negative regulation of intracellular signal transductionGO:19025321670.014
muscle cell differentiationGO:00426922610.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
cellular ketone metabolic processGO:0042180840.014
purine nucleotide biosynthetic processGO:0006164650.014
trna processingGO:0008033110.014
protein processingGO:00164851630.014
regulation of translational initiationGO:0006446150.014
response to heatGO:0009408270.014
purine containing compound biosynthetic processGO:0072522700.013
positive regulation of neuron differentiationGO:00456661410.013
sperm individualizationGO:000729110.013
regulation of g1 s transition of mitotic cell cycleGO:2000045350.013
myeloid cell differentiationGO:00300992330.013
male gamete generationGO:00482322850.013
male sex differentiationGO:00466611090.013
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.013
regulation of cellular amine metabolic processGO:0033238200.013
positive regulation of glucose metabolic processGO:0010907210.012
development of primary female sexual characteristicsGO:0046545730.012
neuron apoptotic processGO:00514021420.012
organelle assemblyGO:00709251770.012
cation transmembrane transportGO:00986552660.012
protein secretionGO:00093061110.012
protein importGO:00170381010.012
dna metabolic processGO:00062593030.012
regulation of organelle organizationGO:00330432890.012
regulation of t cell costimulationGO:200052320.012
epidermis developmentGO:00085441870.012
response to starvationGO:0042594650.012
morphogenesis of embryonic epitheliumGO:00163311590.012
tube closureGO:0060606910.011
respiratory system developmentGO:00605411900.011
positive regulation of erk1 and erk2 cascadeGO:0070374470.011
positive regulation of nucleoside metabolic processGO:0045979910.011
positive regulation of nucleotide catabolic processGO:0030813880.011
negative regulation of mrna metabolic processGO:1903312130.011
regulation of ras protein signal transductionGO:00465781140.011
response to molecule of bacterial originGO:00022371430.011
male gonad developmentGO:0008584880.011
positive regulation of cyclic nucleotide metabolic processGO:0030801240.011
positive regulation of oxidative stress induced cell deathGO:190320960.011
protein import into nucleusGO:0006606950.011
development of primary male sexual characteristicsGO:0046546880.011
modification dependent protein catabolic processGO:00199411330.011
carbohydrate metabolic processGO:00059752300.011
leukocyte proliferationGO:00706611720.010
positive regulation of nucleocytoplasmic transportGO:0046824300.010
rrna processingGO:0006364100.010
determination of heart left right asymmetryGO:0061371480.010
axon guidanceGO:00074111410.010
axonogenesisGO:00074092740.010
lymphocyte activation involved in immune responseGO:0002285930.010
locomotory behaviorGO:00076261950.010
leukocyte migrationGO:00509001240.010
negative regulation of molecular functionGO:00440922580.010
blood circulationGO:00080151950.010
endocytosisGO:00068971680.010

Npm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.031
disease of anatomical entityDOID:700.031
muscle tissue diseaseDOID:6600.031
muscular diseaseDOID:008000000.031
neurodegenerative diseaseDOID:128900.017
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.017
immune system cancerDOID:006008300.017
organ system cancerDOID:005068600.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
hematologic cancerDOID:253100.017
physical disorderDOID:008001500.015
motor neuron diseaseDOID:23100.015
amyotrophic lateral sclerosisDOID:33200.013