Mus musculus

141 known processes

Aars

alanyl-tRNA synthetase

(Aliases: MGC37368,C76919,AI316495,sti)

Aars biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amino acid activationGO:004303810.816
trna aminoacylation for protein translationGO:000641810.694
trna metabolic processGO:0006399110.421
cellular amino acid metabolic processGO:00065201030.352
translationGO:0006412930.164
nucleobase containing small molecule metabolic processGO:00550863520.116
ribonucleoside triphosphate catabolic processGO:00092031990.090
cellular amine metabolic processGO:0044106440.088
nucleoside triphosphate metabolic processGO:00091412300.087
purine nucleoside triphosphate catabolic processGO:00091462030.082
protein modification by small protein conjugation or removalGO:00706472070.080
nucleotide metabolic processGO:00091173320.078
cytoplasmic translational initiationGO:000218330.074
trna aminoacylationGO:004303910.073
regulation of cellular amine metabolic processGO:0033238200.065
ribonucleotide catabolic processGO:00092612080.062
gonad developmentGO:00084061410.060
organonitrogen compound catabolic processGO:19015652640.057
purine ribonucleoside metabolic processGO:00461282410.057
purine containing compound catabolic processGO:00725232130.056
regulation of cellular ketone metabolic processGO:0010565660.056
purine containing compound metabolic processGO:00725213110.056
modification dependent macromolecule catabolic processGO:00436321330.055
ribose phosphate metabolic processGO:00196932910.054
purine nucleoside metabolic processGO:00422782410.054
cellular protein catabolic processGO:00442571550.050
purine ribonucleoside triphosphate catabolic processGO:00092071990.047
carbohydrate metabolic processGO:00059752300.047
heterocycle catabolic processGO:00467002800.047
positive regulation of cellular catabolic processGO:00313311480.046
male gamete generationGO:00482322850.046
ribonucleoside monophosphate catabolic processGO:0009158570.044
amine metabolic processGO:0009308450.044
carbohydrate derivative catabolic processGO:19011362310.044
carbohydrate biosynthetic processGO:0016051740.043
dna metabolic processGO:00062593030.043
negative regulation of protein metabolic processGO:00512482820.043
glycosyl compound catabolic processGO:19016582060.043
protein modification by small protein conjugationGO:00324461870.041
ribonucleoside metabolic processGO:00091192450.040
cellular ketone metabolic processGO:0042180840.040
glucose metabolic processGO:0006006920.039
cristae formationGO:004240730.039
purine ribonucleoside triphosphate metabolic processGO:00092052200.039
positive regulation of cellular amine metabolic processGO:003324050.037
nucleoside phosphate metabolic processGO:00067533380.037
nucleoside catabolic processGO:00091642060.036
response to endoplasmic reticulum stressGO:0034976530.036
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046310.034
ribonucleoside catabolic processGO:00424542060.034
regulation of cellular response to oxidative stressGO:1900407190.034
monosaccharide metabolic processGO:00059961060.034
macromolecule catabolic processGO:00090572810.033
positive regulation of protein modification processGO:00314012990.033
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.033
protein ubiquitinationGO:00165671710.032
spermatogenesisGO:00072832840.032
hexose biosynthetic processGO:0019319390.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
regulation of translationGO:0006417710.032
aromatic compound catabolic processGO:00194392860.031
neuron apoptotic processGO:00514021420.031
purine ribonucleotide metabolic processGO:00091502900.031
rhythmic processGO:00485111740.030
organophosphate catabolic processGO:00464342320.030
purine ribonucleoside catabolic processGO:00461302050.030
regulation of ras protein signal transductionGO:00465781140.030
purine nucleoside triphosphate metabolic processGO:00091442260.029
multicellular organism growthGO:00352641610.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.029
nucleoside phosphate catabolic processGO:19012922220.029
purine nucleoside catabolic processGO:00061522050.028
sensory organ morphogenesisGO:00905962420.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
cytokine productionGO:00018163190.028
hexose metabolic processGO:0019318980.028
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.027
purine nucleotide metabolic processGO:00061633020.027
spermatid differentiationGO:00485151150.026
development of primary sexual characteristicsGO:00451371430.026
ion transmembrane transportGO:00342203610.026
mitotic cell cycleGO:00002781950.026
ribonucleotide metabolic processGO:00092592910.025
negative regulation of molecular functionGO:00440922580.025
cellular nitrogen compound catabolic processGO:00442702800.025
lymphocyte differentiationGO:00300982420.024
purine ribonucleotide catabolic processGO:00091542080.024
regulation of cell cycleGO:00517262810.024
purine nucleotide catabolic processGO:00061952110.024
membrane organizationGO:00610242450.023
gland developmentGO:00487323300.023
regulation of lymphocyte activationGO:00512492400.023
small gtpase mediated signal transductionGO:0007264970.023
myeloid leukocyte differentiationGO:00025731190.023
oligosaccharide catabolic processGO:000931320.023
regulation of cellular amino acid metabolic processGO:000652150.022
stem cell differentiationGO:00488632680.022
nucleoside metabolic processGO:00091162460.022
response to extracellular stimulusGO:00099911270.022
translational initiationGO:0006413240.022
methionine transportGO:001582110.022
endocytosisGO:00068971680.021
proteasomal protein catabolic processGO:0010498980.021
nucleoside triphosphate catabolic processGO:00091432050.021
blastocyst developmentGO:0001824800.021
metal ion homeostasisGO:00550651890.021
nucleoside monophosphate metabolic processGO:0009123850.020
regulation of cellular catabolic processGO:00313292420.020
organic hydroxy compound metabolic processGO:19016152030.020
cell type specific apoptotic processGO:00972852680.020
protein catabolic processGO:00301632210.020
maintenance of locationGO:0051235890.020
nucleoside monophosphate catabolic processGO:0009125590.020
cellular response to external stimulusGO:0071496880.020
modification dependent protein catabolic processGO:00199411330.019
positive regulation of gtpase activityGO:0043547850.019
cellular lipid metabolic processGO:00442553230.019
organonitrogen compound biosynthetic processGO:19015661920.019
cellular macromolecule catabolic processGO:00442652060.019
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.019
development of primary female sexual characteristicsGO:0046545730.019
regulation of leukocyte differentiationGO:19021051590.019
atp catabolic processGO:0006200550.019
nucleotide catabolic processGO:00091662170.019
attachment of spindle microtubules to kinetochoreGO:000860840.019
camera type eye developmentGO:00430102660.019
ovarian follicle developmentGO:0001541400.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
protein targetingGO:00066051430.018
regulation of cell activationGO:00508652890.018
spermatid developmentGO:00072861080.018
rna interferenceGO:001624620.018
divalent metal ion transportGO:00708381720.018
connective tissue developmentGO:00614481790.017
inclusion body assemblyGO:007084130.017
folic acid containing compound metabolic processGO:000676030.017
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.017
negative regulation of neuron deathGO:1901215980.017
protein localization to organelleGO:00333651850.017
transmembrane transportGO:00550854120.017
regulation of wnt signaling pathwayGO:00301111230.017
branched chain amino acid transportGO:001580320.017
leukocyte differentiationGO:00025213420.017
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.017
gluconeogenesisGO:0006094390.017
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.016
regulation of transferase activityGO:00513382630.016
neuron deathGO:00709971540.016
circadian regulation of gene expressionGO:0032922480.016
anion transmembrane transportGO:0098656710.016
cation transmembrane transportGO:00986552660.016
forebrain developmentGO:00309003020.016
positive regulation of apoptotic processGO:00430652170.016
regulation of organelle organizationGO:00330432890.016
response to organic cyclic compoundGO:00140701980.016
cellular response to organonitrogen compoundGO:00714171450.016
cellular chemical homeostasisGO:00550822150.016
female sex differentiationGO:0046660840.016
monosaccharide biosynthetic processGO:0046364440.016
carbohydrate derivative biosynthetic processGO:19011371830.016
cellular homeostasisGO:00197252400.016
positive regulation of protein phosphorylationGO:00019342420.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
muscle cell differentiationGO:00426922610.015
t cell activationGO:00421102890.015
negative regulation of phosphorus metabolic processGO:00105631840.015
central nervous system neuron differentiationGO:00219531620.015
regulation of purine nucleotide catabolic processGO:00331211220.015
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.015
carboxylic acid catabolic processGO:0046395510.015
ras protein signal transductionGO:0007265770.015
liver developmentGO:0001889660.015
skeletal system developmentGO:00015013560.015
ubiquitin dependent protein catabolic processGO:00065111290.014
cellular carbohydrate metabolic processGO:00442621190.014
response to acid chemicalGO:00011011110.014
pentose phosphate shuntGO:000609820.014
regulation of cellular component biogenesisGO:00440871810.014
carbohydrate catabolic processGO:0016052320.014
positive regulation of nucleotide metabolic processGO:00459811140.014
cation homeostasisGO:00550802120.014
nuclear importGO:0051170950.014
calcium ion homeostasisGO:00550741270.014
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.014
inorganic ion transmembrane transportGO:00986602340.014
organic acid transportGO:00158491010.014
disaccharide metabolic processGO:000598410.013
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.013
cellular response to extracellular stimulusGO:0031668810.013
defense response to other organismGO:00985421970.013
positive regulation of hydrolase activityGO:00513451480.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
positive regulation of cell deathGO:00109422240.013
cellular protein complex assemblyGO:00436231160.013
positive regulation of cell developmentGO:00107202370.013
apoptotic signaling pathwayGO:00971903060.013
small molecule biosynthetic processGO:00442831320.013
response to nutrient levelsGO:00316671090.013
lung developmentGO:00303241640.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
cellular response to hormone stimulusGO:00328701500.013
organic cyclic compound catabolic processGO:19013612950.012
g protein coupled receptor signaling pathwayGO:00071862430.012
sulfur amino acid transportGO:000010120.012
regulation of cytoskeleton organizationGO:00514931220.012
glycosyl compound metabolic processGO:19016572460.012
polyamine biosynthetic processGO:000659620.012
negative regulation of cellular protein metabolic processGO:00322692470.012
cellular amide metabolic processGO:0043603580.012
response to organonitrogen compoundGO:00102432460.012
maturation of 5 8s rrnaGO:000046010.012
stem cell developmentGO:00488642190.012
fertilizationGO:00095661270.012
regulation of mapk cascadeGO:00434082480.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
protein maturationGO:00516041760.011
regulation of protein catabolic processGO:00421761080.011
chromatin organizationGO:00063252060.011
cellular calcium ion homeostasisGO:00068741190.011
divalent inorganic cation transportGO:00725111780.011
regulation of protein kinase activityGO:00458592320.011
respiratory tube developmentGO:00303231670.011
telencephalon developmentGO:00215371860.011
phospholipid metabolic processGO:0006644870.011
germ cell developmentGO:00072811850.011
Worm
protein polymerizationGO:0051258570.011
renal system developmentGO:00720012250.011
respiratory system developmentGO:00605411900.011
negative regulation of cellular amine metabolic processGO:003323910.011
anion transportGO:00068201770.011
posttranscriptional regulation of gene expressionGO:00106081550.011
nadph regenerationGO:000674020.011
positive regulation of protein catabolic processGO:0045732600.011
response to molecule of bacterial originGO:00022371430.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
microtubule based processGO:00070172360.011
macromolecular complex disassemblyGO:0032984430.011
amino acid transmembrane transportGO:0003333370.011
nuclear transportGO:00511691390.010
intracellular protein transportGO:00068862040.010
cation transportGO:00068123990.010
circadian rhythmGO:00076231140.010
ossificationGO:00015032160.010
hepaticobiliary system developmentGO:0061008670.010
nucleoside phosphate biosynthetic processGO:1901293790.010
cellular response to lipidGO:00713961450.010
transmission of nerve impulseGO:0019226760.010
response to inorganic substanceGO:0010035960.010
gtp catabolic processGO:00061841430.010
nucleotide biosynthetic processGO:0009165780.010
regulation of neuron apoptotic processGO:00435231220.010
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.010
regulation of cytokine productionGO:00018172660.010
positive regulation of protein kinase activityGO:00458601440.010
wnt signaling pathwayGO:00160551880.010
cellular response to dna damage stimulusGO:00069742070.010
response to peptideGO:19016521360.010
cell adhesionGO:00071553290.010
epithelial cell developmentGO:00020641590.010
regulation of neuron projection developmentGO:00109751690.010

Aars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:87000.502
Human
nervous system diseaseDOID:86300.502
Human
disease of anatomical entityDOID:700.502
Human
neuromuscular diseaseDOID:44000.390
Human
charcot marie tooth disease type 2DOID:005053900.385
Human
charcot marie tooth diseaseDOID:1059500.385
Human
central nervous system diseaseDOID:33100.077
neurodegenerative diseaseDOID:128900.033
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
retinal degenerationDOID:846600.013
retinal diseaseDOID:567900.013