Mus musculus

124 known processes

Eif2ak1

eukaryotic translation initiation factor 2 alpha kinase 1

(Aliases: MGC118066,Hri)

Eif2ak1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugationGO:00324461870.123
protein modification by small protein conjugation or removalGO:00706472070.104
small gtpase mediated signal transductionGO:0007264970.092
ras protein signal transductionGO:0007265770.085
cellular ketone metabolic processGO:0042180840.067
amine metabolic processGO:0009308450.064
regulation of cellular amino acid metabolic processGO:000652150.062
protein ubiquitinationGO:00165671710.057
peptidyl amino acid modificationGO:00181933360.054
regulation of cellular ketone metabolic processGO:0010565660.053
transmembrane transportGO:00550854120.051
membrane organizationGO:00610242450.051
cellular response to peptide hormone stimulusGO:0071375920.050
response to peptideGO:19016521360.047
endomembrane system organizationGO:00102561470.046
cellular amine metabolic processGO:0044106440.046
carbohydrate metabolic processGO:00059752300.046
regulation of cell cycleGO:00517262810.046
macroautophagyGO:0016236210.044
posttranscriptional regulation of gene expressionGO:00106081550.044
regulation of cellular amine metabolic processGO:0033238200.044
translationGO:0006412930.043
cellular lipid metabolic processGO:00442553230.043
positive regulation of cellular amino acid metabolic processGO:004576430.042
dephosphorylationGO:00163111290.041
cellular response to hormone stimulusGO:00328701500.041
t cell activationGO:00421102890.041
nucleotide metabolic processGO:00091173320.040
cell type specific apoptotic processGO:00972852680.039
ion transmembrane transportGO:00342203610.039
myeloid cell differentiationGO:00300992330.039
cellular response to organonitrogen compoundGO:00714171450.038
mitotic cell cycleGO:00002781950.038
response to organonitrogen compoundGO:00102432460.038
cellular amino acid metabolic processGO:00065201030.038
positive regulation of macroautophagyGO:001623930.037
organelle assemblyGO:00709251770.037
regulation of translationGO:0006417710.036
organonitrogen compound catabolic processGO:19015652640.035
cation transportGO:00068123990.035
spermatogenesisGO:00072832840.035
protein maturationGO:00516041760.034
positive regulation of protein modification processGO:00314012990.034
intracellular protein transportGO:00068862040.034
nitrogen compound transportGO:00717052710.033
cellular response to insulin stimulusGO:0032869780.033
positive regulation of protein phosphorylationGO:00019342420.033
glucose metabolic processGO:0006006920.033
positive regulation of cellular amine metabolic processGO:003324050.032
proteasomal protein catabolic processGO:0010498980.032
cytoplasmic transportGO:00164822340.032
macromolecule catabolic processGO:00090572810.032
protein catabolic processGO:00301632210.032
regulation of cytokine productionGO:00018172660.031
nucleobase containing small molecule metabolic processGO:00550863520.031
negative regulation of cellular amino acid metabolic processGO:004576300.031
cellular homeostasisGO:00197252400.031
glycerolipid metabolic processGO:00464861220.030
erythrocyte differentiationGO:0030218880.030
male gamete generationGO:00482322850.030
plasma membrane organizationGO:0007009900.030
glycerolipid biosynthetic processGO:0045017500.030
purine ribonucleotide metabolic processGO:00091502900.030
myeloid cell homeostasisGO:00022621140.030
regulation of transferase activityGO:00513382630.029
apoptotic signaling pathwayGO:00971903060.029
negative regulation of cellular amine metabolic processGO:003323910.029
regulation of proteolysisGO:00301621640.029
purine nucleoside triphosphate catabolic processGO:00091462030.028
regulation of translational initiationGO:0006446150.027
muscle cell differentiationGO:00426922610.027
cytokine productionGO:00018163190.027
homeostasis of number of cellsGO:00488722100.027
regulation of hydrolase activityGO:00513362460.027
lipid modificationGO:0030258650.027
cation transmembrane transportGO:00986552660.027
hexose metabolic processGO:0019318980.026
multicellular organismal signalingGO:0035637910.026
proteolysis involved in cellular protein catabolic processGO:00516031470.026
modification dependent protein catabolic processGO:00199411330.025
nucleotide catabolic processGO:00091662170.025
neuronal action potentialGO:0019228540.025
actin filament polymerizationGO:0030041440.025
response to insulinGO:00328681000.025
monosaccharide metabolic processGO:00059961060.025
engulfment of apoptotic cellGO:004365230.025
anion transportGO:00068201770.024
vesicle organizationGO:0016050600.024
regulation of kinase activityGO:00435492490.024
regulation of establishment of protein localizationGO:00702011810.024
lipid biosynthetic processGO:00086101790.024
cellular response to peptideGO:1901653920.024
protein localization to membraneGO:00726571080.024
ubiquitin dependent protein catabolic processGO:00065111290.023
dna metabolic processGO:00062593030.023
positive regulation of endopeptidase activityGO:0010950430.023
organic cyclic compound catabolic processGO:19013612950.023
regulation of cellular catabolic processGO:00313292420.023
cellular protein catabolic processGO:00442571550.023
metal ion homeostasisGO:00550651890.023
regulation of lymphocyte activationGO:00512492400.023
response to endoplasmic reticulum stressGO:0034976530.023
synaptic transmissionGO:00072683290.022
regulation of protein localizationGO:00328802310.022
purine ribonucleoside catabolic processGO:00461302050.022
protein autophosphorylationGO:0046777610.022
negative regulation of cellular protein metabolic processGO:00322692470.022
regulation of cell cycle processGO:00105641600.022
cellular chemical homeostasisGO:00550822150.022
response to nutrient levelsGO:00316671090.022
protein localization to organelleGO:00333651850.022
vacuole organizationGO:0007033380.022
cation homeostasisGO:00550802120.022
multicellular organism growthGO:00352641610.022
phosphatidylinositol phosphorylationGO:0046854230.021
organophosphate catabolic processGO:00464342320.021
stem cell differentiationGO:00488632680.021
autophagic vacuole assemblyGO:0000045130.021
cellular response to starvationGO:0009267570.021
compound eye developmentGO:004874910.021
embryonic organ morphogenesisGO:00485622760.021
positive regulation of proteolysisGO:0045862850.021
nucleoside phosphate metabolic processGO:00067533380.021
regulation of transmembrane transportGO:00347621280.021
glycerophospholipid metabolic processGO:0006650710.021
negative regulation of cell cycleGO:00457861230.021
regulation of membrane potentialGO:00423911920.021
immune effector processGO:00022523210.021
cellular ion homeostasisGO:00068731650.021
organic acid transportGO:00158491010.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
chromatin modificationGO:00165681870.021
carbohydrate derivative catabolic processGO:19011362310.020
spermatid differentiationGO:00485151150.020
phospholipid metabolic processGO:0006644870.020
aromatic compound catabolic processGO:00194392860.020
cellular macromolecule catabolic processGO:00442652060.020
inorganic ion transmembrane transportGO:00986602340.020
negative regulation of cellular component organizationGO:00511291940.020
purine nucleoside triphosphate metabolic processGO:00091442260.019
rho protein signal transductionGO:0007266320.019
microtubule based processGO:00070172360.019
actin cytoskeleton organizationGO:00300362200.019
positive regulation of programmed cell deathGO:00430682180.019
purine nucleotide metabolic processGO:00061633020.019
inorganic cation transmembrane transportGO:00986622070.019
glycosyl compound metabolic processGO:19016572460.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
ribonucleotide metabolic processGO:00092592910.019
regulation of mapk cascadeGO:00434082480.019
regulation of cell activationGO:00508652890.019
oxidation reduction processGO:00551143420.019
regulation of protein stabilityGO:0031647520.019
regulation of protein kinase activityGO:00458592320.019
mapk cascadeGO:00001652810.019
protein processingGO:00164851630.019
protein polymerizationGO:0051258570.019
peptidyl threonine phosphorylationGO:0018107310.019
cellular calcium ion homeostasisGO:00068741190.019
regulation of organelle organizationGO:00330432890.019
cellular metal ion homeostasisGO:00068751510.019
nucleoside phosphate catabolic processGO:19012922220.019
inflammatory responseGO:00069542440.019
cellular protein complex assemblyGO:00436231160.018
regulation of cellular component sizeGO:00325351210.018
cellular component assembly involved in morphogenesisGO:00109271390.018
regulation of reactive oxygen species biosynthetic processGO:190342620.018
leukocyte differentiationGO:00025213420.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
negative regulation of phosphorylationGO:00423261660.018
cell adhesionGO:00071553290.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
regulation of ion transmembrane transportGO:00347651190.018
cellular response to dna damage stimulusGO:00069742070.018
cellular carbohydrate metabolic processGO:00442621190.018
negative regulation of intracellular signal transductionGO:19025321670.018
purine nucleotide catabolic processGO:00061952110.018
regulation of apoptotic signaling pathwayGO:20012331970.018
ribose phosphate metabolic processGO:00196932910.018
response to acid chemicalGO:00011011110.018
response to oxidative stressGO:00069791230.018
divalent inorganic cation transportGO:00725111780.018
cognitionGO:00508901490.018
positive regulation of cell deathGO:00109422240.017
purine containing compound metabolic processGO:00725213110.017
sequestering of metal ionGO:0051238190.017
chromatin organizationGO:00063252060.017
ribonucleoside catabolic processGO:00424542060.017
purine ribonucleoside metabolic processGO:00461282410.017
regulation of secretionGO:00510462740.017
endocytosisGO:00068971680.017
response to growth factorGO:00708481980.017
regulation of homeostatic processGO:00328441820.017
purine ribonucleotide catabolic processGO:00091542080.017
gland developmentGO:00487323300.017
lipid phosphorylationGO:0046834250.017
establishment of vesicle localizationGO:0051650810.017
response to light stimulusGO:00094161350.017
positive regulation of cellular catabolic processGO:00313311480.017
meiotic cell cycle processGO:1903046770.017
organic anion transportGO:00157111370.017
maintenance of locationGO:0051235890.017
regulation of protein catabolic processGO:00421761080.017
regulation of vesicle mediated transportGO:00606271390.017
negative regulation of protein metabolic processGO:00512482820.016
divalent inorganic cation homeostasisGO:00725071380.016
negative regulation of protein modification processGO:00314001630.016
regulation of proteasomal protein catabolic processGO:0061136460.016
divalent metal ion transportGO:00708381720.016
mitotic cell cycle processGO:19030471590.016
positive regulation of necrotic cell deathGO:001094010.016
regulation of ras protein signal transductionGO:00465781140.016
transmission of nerve impulseGO:0019226760.016
glucose homeostasisGO:00425931280.016
glycosyl compound catabolic processGO:19016582060.016
reactive nitrogen species metabolic processGO:200105700.016
sequestering of calcium ionGO:0051208180.016
negative regulation of cell developmentGO:00107211690.016
autophagyGO:0006914450.016
mrna metabolic processGO:0016071840.016
response to extracellular stimulusGO:00099911270.016
heterocycle catabolic processGO:00467002800.016
learning or memoryGO:00076111480.016
ribonucleoside metabolic processGO:00091192450.016
carboxylic acid transportGO:00469421000.016
organonitrogen compound biosynthetic processGO:19015661920.015
hexose biosynthetic processGO:0019319390.015
regulation of cell projection organizationGO:00313442060.015
carbohydrate biosynthetic processGO:0016051740.015
nucleoside triphosphate catabolic processGO:00091432050.015
regulation of mitotic cell cycleGO:00073461260.015
action potentialGO:0001508780.015
carbohydrate derivative biosynthetic processGO:19011371830.015
single organism cell adhesionGO:00986021560.015
mitochondrion organizationGO:00070051340.015
establishment of organelle localizationGO:00516561220.015
negative regulation of protein phosphorylationGO:00019331260.015
innate immune responseGO:00450871570.015
methylationGO:00322591340.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
germ cell developmentGO:00072811850.015
wnt signaling pathwayGO:00160551880.015
regionalizationGO:00030023370.015
protein targetingGO:00066051430.015
organic hydroxy compound metabolic processGO:19016152030.015
negative regulation of nervous system developmentGO:00519611560.015
cellular response to amino acid stimulusGO:0071230290.015
phagocytosisGO:0006909660.015
regulation of protein serine threonine kinase activityGO:00719001570.015
positive regulation of apoptotic processGO:00430652170.015
regulation of glucose metabolic processGO:0010906600.014
citrate metabolic processGO:000610130.014
purine nucleoside catabolic processGO:00061522050.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
cellular response to external stimulusGO:0071496880.014
carbohydrate homeostasisGO:00335001280.014
negative regulation of phosphate metabolic processGO:00459361840.014
peptidyl serine phosphorylationGO:0018105740.014
negative regulation of cell proliferationGO:00082852960.014
membrane fusionGO:0061025380.014
vesicle localizationGO:0051648860.014
response to osmotic stressGO:0006970210.014
lymphocyte differentiationGO:00300982420.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
macromolecule methylationGO:00434141200.014
regulation of cellular protein catabolic processGO:1903362610.014
regulation of clathrin mediated endocytosisGO:200036940.014
nucleocytoplasmic transportGO:00069131390.014
organelle fissionGO:00482851700.014
b cell differentiationGO:0030183780.014
mitochondrion distributionGO:004831140.014
adaptive immune responseGO:00022501550.014
sensory organ morphogenesisGO:00905962420.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
positive regulation of mapk cascadeGO:00434101700.014
cellular response to cytokine stimulusGO:00713451890.014
guanosine containing compound metabolic processGO:19010681440.014
protein localization to nucleusGO:00345041210.014
axonogenesisGO:00074092740.014
protein methylationGO:0006479810.013
lateral inhibitionGO:004633110.013
nucleoside metabolic processGO:00091162460.013
nuclear divisionGO:00002801580.013
glycerophospholipid biosynthetic processGO:0046474320.013
positive regulation of protein transportGO:0051222930.013
insulin receptor signaling pathwayGO:0008286490.013
meiotic cell cycleGO:00513211220.013
response to inorganic substanceGO:0010035960.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
nucleoside triphosphate metabolic processGO:00091412300.013
cellular nitrogen compound catabolic processGO:00442702800.013
peptidyl serine modificationGO:0018209830.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
peptide transportGO:00158331330.013
lymphocyte proliferationGO:00466511640.013
b cell activationGO:00421131610.013
retrograde transport endosome to golgiGO:004214720.013
cell divisionGO:00513011200.013
organophosphate biosynthetic processGO:00904071220.013
ribonucleotide catabolic processGO:00092612080.013
striated muscle tissue developmentGO:00147062930.013
phosphatidylinositol metabolic processGO:0046488450.013
muscle tissue developmentGO:00605373080.013
regulation of ion transportGO:00432692150.012
guanosine containing compound catabolic processGO:19010691440.012
negative regulation of phosphorus metabolic processGO:00105631840.012
positive regulation of intracellular transportGO:0032388700.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
adult behaviorGO:00305341350.012
cilium morphogenesisGO:00602711020.012
digestive tract developmentGO:00485651900.012
histone modificationGO:00165701590.012
protein localization to plasma membraneGO:0072659570.012
response to radiationGO:00093141650.012
multi multicellular organism processGO:00447061090.012
stem cell developmentGO:00488642190.012
positive regulation of transferase activityGO:00513471670.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of cell migrationGO:00303342190.012
rna interferenceGO:001624620.012
regulation of leukocyte differentiationGO:19021051590.012
rna processingGO:00063961050.012
neuron deathGO:00709971540.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
glycoprotein biosynthetic processGO:0009101890.012
covalent chromatin modificationGO:00165691630.012
macromolecular complex disassemblyGO:0032984430.012
negative regulation of molecular functionGO:00440922580.012
negative regulation of immune system processGO:00026832090.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.012
development of primary sexual characteristicsGO:00451371430.011
exocytosisGO:00068871210.011
calcium ion homeostasisGO:00550741270.011
skeletal system developmentGO:00015013560.011
cellular response to growth factor stimulusGO:00713631970.011
regulation of nucleoside metabolic processGO:00091181300.011
chemotaxisGO:00069352470.011
blastocyst developmentGO:0001824800.011
establishment of protein localization to membraneGO:0090150540.011
calcium ion transportGO:00068161590.011
cellular response to extracellular stimulusGO:0031668810.011
regulation of t cell activationGO:00508631700.011
g protein coupled receptor signaling pathwayGO:00071862430.011
notch signaling pathwayGO:0007219710.011
regulation of actin filament based processGO:0032970990.011
retina development in camera type eyeGO:00600411190.011
regulation of purine nucleotide metabolic processGO:19005421690.011
skeletal system morphogenesisGO:00487052030.011
regulation of hormone levelsGO:00108172110.011
regulation of cytoplasmic transportGO:19036491120.011
regulation of peptidase activityGO:0052547960.011
glycoprotein metabolic processGO:00091001160.011
intra golgi vesicle mediated transportGO:000689110.011
cell growthGO:00160491300.011
regulation of cellular component biogenesisGO:00440871810.011
negative regulation of glial cell proliferationGO:006025340.011
regulation of endocytosisGO:0030100690.011
regulation of endopeptidase activityGO:0052548890.011
response to peptide hormoneGO:00434341270.011
positive regulation of gtpase activityGO:0043547850.011
phosphorylated carbohydrate dephosphorylationGO:004683840.011
defense response to other organismGO:00985421970.011
cell fate commitmentGO:00451652100.011
transition metal ion transportGO:0000041380.011
regulation of cell sizeGO:0008361720.011
negative regulation of cell cycle processGO:0010948690.011
positive regulation of secretion by cellGO:19035321140.011
phospholipid biosynthetic processGO:0008654360.011
wound healingGO:00420601570.011
amide transportGO:00428861380.010
regulation of protein processingGO:0070613960.010
gtp catabolic processGO:00061841430.010
anion transmembrane transportGO:0098656710.010
positive regulation of cell activationGO:00508671580.010
regulation of cytoskeleton organizationGO:00514931220.010
regulation of striated muscle cell differentiationGO:0051153810.010
regulation of body fluid levelsGO:00508781620.010
regulation of anatomical structure sizeGO:00900661780.010
ear developmentGO:00435832000.010
organic acid biosynthetic processGO:0016053860.010
regulation of cellular carbohydrate metabolic processGO:0010675750.010
peptidyl threonine modificationGO:0018210310.010
organelle localizationGO:00516401790.010
neuron apoptotic processGO:00514021420.010
meiotic nuclear divisionGO:00071261150.010
ossificationGO:00015032160.010
actin filament organizationGO:00070151130.010
receptor mediated endocytosisGO:0006898510.010
fatty acid transmembrane transportGO:190200110.010
positive regulation of peptidase activityGO:0010952490.010
oocyte axis specificationGO:000730920.010
positive regulation of homeostatic processGO:0032846640.010
axon ensheathmentGO:0008366760.010
purine containing compound catabolic processGO:00725232130.010
cell substrate adhesionGO:00315891300.010
actin polymerization or depolymerizationGO:0008154540.010
l amino acid transportGO:0015807320.010
carbohydrate transportGO:0008643620.010
asymmetric stem cell divisionGO:009872230.010
small molecule catabolic processGO:0044282710.010
reactive oxygen species metabolic processGO:0072593840.010
multicellular organismal homeostasisGO:00488711640.010
monosaccharide transportGO:0015749580.010

Eif2ak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
immune system diseaseDOID:291400.027
hematopoietic system diseaseDOID:7400.025
nervous system diseaseDOID:86300.021
central nervous system diseaseDOID:33100.018
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.014
disease of metabolismDOID:001466700.011
neurodegenerative diseaseDOID:128900.011