Mus musculus

35 known processes

Erap1

endoplasmic reticulum aminopeptidase 1

(Aliases: ERAAP,PILSA,Arts1,PILSAP)

Erap1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cytokine productionGO:00018172660.408
ribose phosphate metabolic processGO:00196932910.218
aromatic compound catabolic processGO:00194392860.174
interspecies interaction between organismsGO:0044419830.168
organic cyclic compound catabolic processGO:19013612950.166
nucleoside phosphate metabolic processGO:00067533380.153
regulation of response to biotic stimulusGO:0002831380.152
regulation of intracellular transportGO:00323861590.148
type i interferon productionGO:0032606290.148
cytokine productionGO:00018163190.145
regulation of defense responseGO:00313472330.140
regulation of innate immune responseGO:0045088910.138
response to lipopolysaccharideGO:00324961280.132
innate immune responseGO:00450871570.127
positive regulation of interferon alpha productionGO:003272740.118
symbiosis encompassing mutualism through parasitismGO:0044403830.118
nucleoside catabolic processGO:00091642060.106
glycosyl compound metabolic processGO:19016572460.100
regulation of type i interferon productionGO:0032479220.099
immune effector processGO:00022523210.092
positive regulation of hydrolase activityGO:00513451480.092
nucleobase containing small molecule metabolic processGO:00550863520.089
purine ribonucleotide catabolic processGO:00091542080.087
heterocycle catabolic processGO:00467002800.087
cellular response to molecule of bacterial originGO:0071219830.086
carbohydrate derivative catabolic processGO:19011362310.084
purine nucleoside triphosphate catabolic processGO:00091462030.082
regulation of multi organism processGO:00439001110.079
negative regulation of cellular protein metabolic processGO:00322692470.078
nucleoside triphosphate metabolic processGO:00091412300.074
purine ribonucleotide metabolic processGO:00091502900.069
intracellular protein transportGO:00068862040.068
cellular nitrogen compound catabolic processGO:00442702800.067
cellular response to lipopolysaccharideGO:0071222770.064
cellular response to lipidGO:00713961450.064
nucleoside phosphate catabolic processGO:19012922220.063
defense response to other organismGO:00985421970.063
positive regulation of defense responseGO:00313491240.062
cellular response to interferon betaGO:0035458210.062
purine nucleoside catabolic processGO:00061522050.060
ribonucleoside triphosphate metabolic processGO:00091992200.059
regulation of intracellular protein transportGO:0033157820.059
nucleotide metabolic processGO:00091173320.058
cytoplasmic transportGO:00164822340.058
activation of immune responseGO:00022531380.057
purine containing compound metabolic processGO:00725213110.056
nucleoside triphosphate catabolic processGO:00091432050.056
cellular response to cytokine stimulusGO:00713451890.055
purine ribonucleoside catabolic processGO:00461302050.055
purine nucleoside triphosphate metabolic processGO:00091442260.055
rig i signaling pathwayGO:003952940.053
dna metabolic processGO:00062593030.053
purine nucleotide catabolic processGO:00061952110.053
defense response to bacteriumGO:00427421190.052
purine nucleoside metabolic processGO:00422782410.051
ribonucleotide metabolic processGO:00092592910.050
cellular response to biotic stimulusGO:0071216920.050
response to organic cyclic compoundGO:00140701980.049
protein import into nucleusGO:0006606950.049
purine nucleotide metabolic processGO:00061633020.048
negative regulation of molecular functionGO:00440922580.047
defense response to virusGO:0051607680.047
cellular ketone metabolic processGO:0042180840.047
regulation of protein localizationGO:00328802310.046
purine ribonucleoside metabolic processGO:00461282410.046
ribonucleoside triphosphate catabolic processGO:00092031990.046
response to molecule of bacterial originGO:00022371430.045
regulation of peptidase activityGO:0052547960.044
ribonucleoside metabolic processGO:00091192450.043
protein importGO:00170381010.043
purine containing compound catabolic processGO:00725232130.043
interleukin 8 productionGO:003263740.042
purine ribonucleoside triphosphate metabolic processGO:00092052200.042
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.042
regulation of antimicrobial peptide biosynthetic processGO:000280510.042
protein modification by small protein conjugation or removalGO:00706472070.042
regulation of hydrolase activityGO:00513362460.042
protein localization to organelleGO:00333651850.041
organonitrogen compound catabolic processGO:19015652640.041
nucleotide catabolic processGO:00091662170.041
regulation of cellular catabolic processGO:00313292420.040
b cell activationGO:00421131610.039
leukocyte mediated cytotoxicityGO:0001909620.039
positive regulation of innate immune responseGO:0045089800.038
leukocyte mediated immunityGO:00024431740.038
nucleoside metabolic processGO:00091162460.038
protein modification by small protein conjugationGO:00324461870.038
inflammatory responseGO:00069542440.038
glycosyl compound catabolic processGO:19016582060.037
positive regulation of type i interferon productionGO:0032481140.037
activation of innate immune responseGO:0002218560.037
response to organonitrogen compoundGO:00102432460.036
response to dsrnaGO:0043331300.035
nucleoside monophosphate metabolic processGO:0009123850.035
macromolecule catabolic processGO:00090572810.035
Mouse
protein maturationGO:00516041760.035
regulation of establishment of protein localizationGO:00702011810.034
negative regulation of protein metabolic processGO:00512482820.034
cell type specific apoptotic processGO:00972852680.034
response to interferon gammaGO:0034341340.034
immune response regulating signaling pathwayGO:00027641250.034
atp metabolic processGO:0046034750.033
apoptotic signaling pathwayGO:00971903060.033
defense response to gram positive bacteriumGO:0050830500.033
myeloid leukocyte differentiationGO:00025731190.033
cellular amino acid metabolic processGO:00065201030.033
membrane organizationGO:00610242450.032
establishment of protein localization to organelleGO:00725941180.032
positive regulation of immune effector processGO:00026991070.032
regulation of membrane potentialGO:00423911920.032
regulation of defense response to bacteriumGO:190042430.032
ribonucleoside monophosphate metabolic processGO:0009161800.032
ribonucleotide catabolic processGO:00092612080.032
positive regulation of cytokine productionGO:00018191740.031
nucleocytoplasmic transportGO:00069131390.031
negative regulation of cytokine productionGO:0001818840.031
regulation of proteolysisGO:00301621640.031
positive regulation of proteolysisGO:0045862850.031
leukocyte differentiationGO:00025213420.030
negative regulation of phosphorus metabolic processGO:00105631840.030
immune response activating signal transductionGO:00027571160.030
metal ion homeostasisGO:00550651890.030
nitrogen compound transportGO:00717052710.030
regulation of nucleocytoplasmic transportGO:0046822730.029
negative regulation of immune system processGO:00026832090.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
organophosphate catabolic processGO:00464342320.029
regulation of protein targetingGO:1903533610.028
cellular amine metabolic processGO:0044106440.028
lymphocyte mediated immunityGO:00024491390.028
stem cell developmentGO:00488642190.028
respiratory system developmentGO:00605411900.028
transmembrane transportGO:00550854120.028
posttranscriptional regulation of gene expressionGO:00106081550.028
hatchingGO:003518840.028
regulation of schwann cell proliferationGO:001062420.027
cellular response to dna damage stimulusGO:00069742070.026
reactive oxygen species metabolic processGO:0072593840.026
regulation of reactive oxygen species metabolic processGO:2000377400.026
negative regulation of phosphorylationGO:00423261660.026
negative regulation of multi organism processGO:0043901680.026
protein processingGO:00164851630.025
single organism nuclear importGO:1902593950.025
negative regulation of cell proliferationGO:00082852960.025
negative regulation of phosphate metabolic processGO:00459361840.025
negative regulation of protein phosphorylationGO:00019331260.025
negative regulation of protein modification processGO:00314001630.025
regulation of leukocyte apoptotic processGO:2000106560.025
compound eye developmentGO:004874910.024
gtp catabolic processGO:00061841430.024
nuclear transportGO:00511691390.024
regulation of interferon alpha productionGO:003264750.024
purine nucleoside monophosphate metabolic processGO:0009126810.024
negative regulation of intracellular transportGO:0032387380.024
positive regulation of programmed cell deathGO:00430682180.024
positive regulation of antimicrobial humoral responseGO:000276020.024
epithelial tube morphogenesisGO:00605623030.023
oxidation reduction processGO:00551143420.023
mitochondrion organizationGO:00070051340.023
viral life cycleGO:0019058360.023
regulation of autophagyGO:0010506300.023
membrane depolarizationGO:0051899640.023
regulation of cytoplasmic transportGO:19036491120.023
regulation of antimicrobial humoral responseGO:000275930.023
carbohydrate metabolic processGO:00059752300.023
ribonucleoside catabolic processGO:00424542060.022
protein ubiquitinationGO:00165671710.022
cation transportGO:00068123990.022
regulation of nlrp3 inflammasome complex assemblyGO:190022540.022
epidermis developmentGO:00085441870.022
maintenance of locationGO:0051235890.022
defense response to gram negative bacteriumGO:0050829280.022
positive regulation of rig i signaling pathwayGO:190024610.022
protein localization to nucleusGO:00345041210.022
antimicrobial peptide biosynthetic processGO:000277720.022
lung developmentGO:00303241640.022
regulation of interleukin 1 alpha productionGO:003265040.021
pattern recognition receptor signaling pathwayGO:0002221470.021
regulation of rig i signaling pathwayGO:003953520.021
negative regulation of intracellular protein transportGO:0090317270.021
regulation of cellular ketone metabolic processGO:0010565660.021
positive regulation of apoptotic processGO:00430652170.021
protein targetingGO:00066051430.021
cellular lipid metabolic processGO:00442553230.021
regulation of protein transportGO:00512231630.021
extrinsic apoptotic signaling pathwayGO:00971911260.020
regulation of endopeptidase activityGO:0052548890.020
negative regulation of interferon alpha productionGO:003268710.020
regulation of lymphocyte activationGO:00512492400.020
regulation of secretionGO:00510462740.020
ion transmembrane transportGO:00342203610.020
macromolecule glycosylationGO:0043413550.020
regulation of protein localization to nucleusGO:1900180600.019
respiratory tube developmentGO:00303231670.019
progesterone metabolic processGO:004244840.019
cellular response to hormone stimulusGO:00328701500.019
negative regulation of nervous system developmentGO:00519611560.019
extracellular matrix organizationGO:00301981470.019
glycoprotein metabolic processGO:00091001160.019
natural killer cell proliferationGO:000178730.019
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.019
negative regulation of protein transportGO:0051224460.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
protein catabolic processGO:00301632210.018
Mouse
cell killingGO:0001906670.018
regulation of cell cycleGO:00517262810.018
response to endoplasmic reticulum stressGO:0034976530.018
organophosphate biosynthetic processGO:00904071220.018
positive regulation of cellular catabolic processGO:00313311480.018
pyroptosisGO:007026980.018
positive regulation of cell deathGO:00109422240.018
innate immune response activating signal transductionGO:0002758500.018
endomembrane system organizationGO:00102561470.018
regulation of response to woundingGO:19030341890.018
regulation of interleukin 8 productionGO:003267730.018
nucleic acid phosphodiester bond hydrolysisGO:0090305490.018
antibacterial peptide productionGO:000277820.017
rna processingGO:00063961050.017
nuclear importGO:0051170950.017
cellular macromolecule catabolic processGO:00442652060.017
adaptive immune responseGO:00022501550.017
purine ribonucleoside monophosphate metabolic processGO:0009167800.017
regulation of protein import into nucleusGO:0042306520.017
monocarboxylic acid metabolic processGO:00327871910.017
regulation of transferase activityGO:00513382630.017
peptide metabolic processGO:0006518460.017
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.017
regulation of leukocyte differentiationGO:19021051590.017
cellular component assembly involved in morphogenesisGO:00109271390.017
multicellular organismal signalingGO:0035637910.016
muscle cell differentiationGO:00426922610.016
regulation of protein ubiquitinationGO:0031396520.016
stem cell differentiationGO:00488632680.016
regulation of protein modification by small protein conjugation or removalGO:1903320570.016
viral processGO:0016032410.016
spleen developmentGO:0048536390.016
cellular amide metabolic processGO:0043603580.016
positive regulation of endopeptidase activityGO:0010950430.016
positive regulation of viral entry into host cellGO:004659830.016
blood vessel morphogenesisGO:00485142850.016
regulation of cell activationGO:00508652890.016
dna repairGO:00062811070.016
amine metabolic processGO:0009308450.016
muscle cell developmentGO:00550011330.016
guanosine containing compound metabolic processGO:19010681440.016
connective tissue developmentGO:00614481790.016
carbohydrate derivative biosynthetic processGO:19011371830.016
cell adhesionGO:00071553290.016
regulation of hormone levelsGO:00108172110.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
guanosine containing compound catabolic processGO:19010691440.016
digestive system developmentGO:00551232000.016
interferon beta productionGO:0032608160.016
cell activation involved in immune responseGO:00022631260.016
multicellular organism growthGO:00352641610.016
multicellular organismal homeostasisGO:00488711640.016
leukocyte apoptotic processGO:0071887710.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
organonitrogen compound biosynthetic processGO:19015661920.015
i kappab kinase nf kappab signalingGO:0007249850.015
regulation of purine nucleotide metabolic processGO:19005421690.015
positive regulation of type i interferon mediated signaling pathwayGO:006034040.015
myeloid cell differentiationGO:00300992330.015
action potentialGO:0001508780.015
regulation of mapk cascadeGO:00434082480.015
er nucleus signaling pathwayGO:0006984270.015
anion transportGO:00068201770.015
lipid biosynthetic processGO:00086101790.015
regulation of defense response to virus by hostGO:005069180.015
cellular carbohydrate metabolic processGO:00442621190.015
positive regulation of viral genome replicationGO:004507020.015
lymphocyte apoptotic processGO:0070227540.015
negative regulation of intracellular signal transductionGO:19025321670.015
cellular metal ion homeostasisGO:00068751510.014
muscle tissue developmentGO:00605373080.014
sensory perceptionGO:00076002450.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
glycosylationGO:0070085620.014
cellular ion homeostasisGO:00068731650.014
fatty acid metabolic processGO:00066311210.014
rna interferenceGO:001624620.014
viral gene expressionGO:001908030.014
angiogenesisGO:00015252010.014
adhesion of symbiont to hostGO:004440680.014
cation homeostasisGO:00550802120.014
regulation of cellular amino acid metabolic processGO:000652150.014
negative regulation of cell developmentGO:00107211690.014
organic hydroxy compound metabolic processGO:19016152030.014
cellular response to oxidative stressGO:0034599760.014
epithelial cell proliferationGO:00506731740.014
regulation of secretion by cellGO:19035302490.014
positive regulation of mda 5 signaling pathwayGO:190024510.014
ossificationGO:00015032160.014
neuronal action potentialGO:0019228540.014
purine ribonucleoside monophosphate catabolic processGO:0009169570.013
lymphocyte differentiationGO:00300982420.013
regulation of neuron differentiationGO:00456642810.013
peptidyl amino acid modificationGO:00181933360.013
regulation of b cell activationGO:0050864810.013
cation transmembrane transportGO:00986552660.013
chromatin organizationGO:00063252060.013
covalent chromatin modificationGO:00165691630.013
positive regulation of peptidase activityGO:0010952490.013
positive regulation of cysteine type endopeptidase activityGO:2001056390.013
autophagyGO:0006914450.013
amide transportGO:00428861380.013
leukocyte homeostasisGO:0001776790.013
skeletal system developmentGO:00015013560.013
cellular response to external stimulusGO:0071496880.013
regulation of apoptotic signaling pathwayGO:20012331970.013
negative regulation of cytoplasmic transportGO:1903650290.013
alcohol metabolic processGO:00060661160.013
hormone metabolic processGO:0042445860.013
epithelial cell developmentGO:00020641590.013
negative regulation of cellular component organizationGO:00511291940.013
striated muscle tissue developmentGO:00147062930.012
urogenital system developmentGO:00016552610.012
Mouse
anatomical structure homeostasisGO:00602491450.012
interleukin 6 productionGO:0032635580.012
antimicrobial peptide productionGO:000277520.012
regulation of interferon gamma productionGO:0032649570.012
regulation of cellular amine metabolic processGO:0033238200.012
positive regulation of nervous system developmentGO:00519622210.012
regulation of neuron deathGO:19012141340.012
positive regulation of cellular amine metabolic processGO:003324050.012
limb morphogenesisGO:00351081490.012
ear developmentGO:00435832000.012
engulfment of apoptotic cellGO:004365230.012
synaptic transmissionGO:00072683290.012
positive regulation of protein transportGO:0051222930.012
meiotic cell cycle processGO:1903046770.012
regulation of viral genome replicationGO:0045069130.012
positive regulation of cell developmentGO:00107202370.012
double strand break repairGO:0006302480.012
homeostasis of number of cellsGO:00488722100.012
negative regulation of protein localization to nucleusGO:1900181230.012
regulation of actin nucleationGO:005112540.012
rhythmic processGO:00485111740.011
regulation of protein catabolic processGO:00421761080.011
t cell activationGO:00421102890.011
regulation of lipid metabolic processGO:00192161180.011
extracellular structure organizationGO:00430621480.011
t cell mediated cytotoxicityGO:0001913260.011
atp catabolic processGO:0006200550.011
regulation of body fluid levelsGO:00508781620.011
defense response to protozoanGO:0042832250.011
cellular response to organic cyclic compoundGO:0071407870.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
regulation of t cell activationGO:00508631700.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
regulation of natural killer cell mediated cytotoxicityGO:0042269190.011
mapk cascadeGO:00001652810.011
neuron apoptotic processGO:00514021420.011
morphogenesis of a branching structureGO:00017632030.011
b cell activation involved in immune responseGO:0002312500.011
stem cell maintenanceGO:00198271300.011
regulation of antimicrobial peptide productionGO:000278410.011
mrna metabolic processGO:0016071840.011
regulation of lymphocyte differentiationGO:00456191070.011
inorganic ion transmembrane transportGO:00986602340.011
sequestering of metal ionGO:0051238190.011
activation of cysteine type endopeptidase activityGO:0097202270.011
organism emergence from protective structureGO:007168440.011
organic anion transportGO:00157111370.011
lymphocyte activation involved in immune responseGO:0002285930.011
positive regulation of interleukin 1 alpha secretionGO:005071730.011
response to nutrient levelsGO:00316671090.011
gtp metabolic processGO:00460391440.011
positive regulation of nucleotide metabolic processGO:00459811140.011
small gtpase mediated signal transductionGO:0007264970.011
hematopoietic progenitor cell differentiationGO:00022441430.011
regulation of lymphocyte apoptotic processGO:0070228410.011
lipid localizationGO:00108761260.011
natural killer cell activationGO:0030101440.011
sequestering of calcium ionGO:0051208180.011
regulation of kinase activityGO:00435492490.011
regulation of production of molecular mediator of immune responseGO:0002700650.011
glycoprotein biosynthetic processGO:0009101890.011
immunoglobulin productionGO:0002377730.011
microtubule based processGO:00070172360.011
response to oxidative stressGO:00069791230.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
limb developmentGO:00601731660.010
response to peptide hormoneGO:00434341270.010
schwann cell proliferationGO:001401020.010
regulation of purine nucleotide catabolic processGO:00331211220.010
positive regulation of lymphocyte activationGO:00512511400.010
inorganic cation transmembrane transportGO:00986622070.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
cartilage developmentGO:00512161400.010
negative regulation of cellular amine metabolic processGO:003323910.010
striated muscle cell developmentGO:00550021250.010
response to light stimulusGO:00094161350.010
negative regulation of protein modification by small protein conjugation or removalGO:1903321200.010
cellular chemical homeostasisGO:00550822150.010
cellular response to organonitrogen compoundGO:00714171450.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
carbohydrate homeostasisGO:00335001280.010
skin developmentGO:00435882200.010
positive regulation of nucleotide catabolic processGO:0030813880.010
regulation of reactive oxygen species biosynthetic processGO:190342620.010
t cell apoptotic processGO:0070231390.010
negative regulation of immune effector processGO:0002698550.010
response to radiationGO:00093141650.010
protein glycosylationGO:0006486550.010
response to growth factorGO:00708481980.010
glial cell differentiationGO:00100011310.010
production of molecular mediator of immune responseGO:00024401030.010
cytokine mediated signaling pathwayGO:00192211150.010
cell fate commitmentGO:00451652100.010
nucleoside monophosphate catabolic processGO:0009125590.010

Erap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.037
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013