Mus musculus

95 known processes

Ezh1

enhancer of zeste homolog 1 (Drosophila)

(Aliases: mKIAA0388,AW557915)

Ezh1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of histone h3 k27 methylationGO:006108740.925
regulation of histone h3 k27 methylationGO:006108560.838
histone methylationGO:0016571710.838
histone lysine methylationGO:0034968500.709
regulation of excitatory postsynaptic membrane potentialGO:0060079410.663
regulation of skeletal muscle contractionGO:001481930.639
macromolecule methylationGO:00434141200.613
negative regulation of histone methylationGO:0031061100.585
establishment or maintenance of actin cytoskeleton polarityGO:003095010.512
establishment or maintenance of cytoskeleton polarityGO:003095220.407
cation transportGO:00068123990.389
synaptic transmissionGO:00072683290.383
regulation of postsynaptic membrane potentialGO:0060078480.380
negative regulation of protein modification processGO:00314001630.369
protein methylationGO:0006479810.359
regulation of histone methylationGO:0031060300.356
regulation of synapse structural plasticityGO:005182340.344
negative regulation of transferase activityGO:0051348850.338
negative regulation of phosphorus metabolic processGO:00105631840.316
cytokinetic processGO:003250620.299
histone h3 k9 methylationGO:0051567170.285
Fly
endomembrane system organizationGO:00102561470.272
histone h3 k27 methylationGO:0070734110.269
mapk cascadeGO:00001652810.264
negative regulation of phosphate metabolic processGO:00459361840.259
negative regulation of protein metabolic processGO:00512482820.259
metal ion homeostasisGO:00550651890.249
actin cytoskeleton organizationGO:00300362200.218
negative regulation of phosphorylationGO:00423261660.215
muscle cell differentiationGO:00426922610.209
Mouse
dendrite self avoidanceGO:007059320.197
purine nucleoside triphosphate catabolic processGO:00091462030.197
regulation of striated muscle contractionGO:0006942250.191
negative regulation of map kinase activityGO:0043407340.187
cell divisionGO:00513011200.182
Worm
establishment or maintenance of cell polarityGO:0007163860.182
ribonucleoside triphosphate catabolic processGO:00092031990.176
covalent chromatin modificationGO:00165691630.168
regulation of membrane potentialGO:00423911920.168
histone modificationGO:00165701590.167
negative regulation of cellular component organizationGO:00511291940.165
regulation of neuron differentiationGO:00456642810.162
regulation of transferase activityGO:00513382630.159
calcium mediated signalingGO:0019722460.159
protein alkylationGO:0008213810.157
negative regulation of protein phosphorylationGO:00019331260.157
membrane organizationGO:00610242450.154
methylationGO:00322591340.153
negative regulation of cellular protein metabolic processGO:00322692470.151
negative regulation of mapk cascadeGO:0043409650.144
ras protein signal transductionGO:0007265770.144
cellular metal ion homeostasisGO:00068751510.143
regulation of metal ion transportGO:00109591060.141
positive regulation of histone methylationGO:0031062160.138
cellular homeostasisGO:00197252400.138
negative regulation of protein serine threonine kinase activityGO:0071901490.130
cellular ion homeostasisGO:00068731650.127
regulation of cell morphogenesis involved in differentiationGO:00107691510.126
negative regulation of cellular amino acid metabolic processGO:004576300.124
negative regulation of kinase activityGO:0033673810.122
stem cell differentiationGO:00488632680.118
cellular amine metabolic processGO:0044106440.116
regulation of cellular ketone metabolic processGO:0010565660.113
purine ribonucleoside triphosphate metabolic processGO:00092052200.111
organophosphate catabolic processGO:00464342320.109
regulation of ion transportGO:00432692150.109
purine nucleoside catabolic processGO:00061522050.108
nucleotide metabolic processGO:00091173320.106
regulation of chromatin modificationGO:1903308570.106
purine containing compound catabolic processGO:00725232130.105
purine nucleoside triphosphate metabolic processGO:00091442260.102
intracellular protein transportGO:00068862040.100
cellular nitrogen compound catabolic processGO:00442702800.100
cellular chemical homeostasisGO:00550822150.099
regulation of kinase activityGO:00435492490.099
regulation of system processGO:00440572000.099
negative regulation of organelle organizationGO:0010639900.098
ribonucleoside metabolic processGO:00091192450.096
nucleoside triphosphate metabolic processGO:00091412300.094
regulation of protein serine threonine kinase activityGO:00719001570.094
nuclear envelope organizationGO:0006998110.093
nucleoside phosphate metabolic processGO:00067533380.091
divalent inorganic cation homeostasisGO:00725071380.090
cellular calcium ion homeostasisGO:00068741190.088
positive regulation of histone h3 k9 methylationGO:005157440.086
regulation of map kinase activityGO:00434051200.085
glycosyl compound metabolic processGO:19016572460.084
cation homeostasisGO:00550802120.082
purine ribonucleoside catabolic processGO:00461302050.081
positive regulation of chromatin modificationGO:1903310280.079
purine ribonucleotide catabolic processGO:00091542080.077
glycerophospholipid metabolic processGO:0006650710.077
sodium ion transportGO:0006814730.076
lipid modificationGO:0030258650.075
regulation of mapk cascadeGO:00434082480.075
calcium ion homeostasisGO:00550741270.074
purine ribonucleoside triphosphate catabolic processGO:00092071990.071
purine ribonucleotide metabolic processGO:00091502900.071
ribose phosphate metabolic processGO:00196932910.070
regulation of cell projection organizationGO:00313442060.070
second messenger mediated signalingGO:0019932730.070
chromatin modificationGO:00165681870.070
negative regulation of molecular functionGO:00440922580.070
muscle contractionGO:00069361010.069
nucleoside triphosphate catabolic processGO:00091432050.069
nucleobase containing small molecule metabolic processGO:00550863520.065
positive regulation of dna templated transcription elongationGO:003278620.065
regulation of blood circulationGO:1903522930.065
protein ubiquitinationGO:00165671710.064
regulation of protein kinase activityGO:00458592320.064
defense response to other organismGO:00985421970.063
cellular lipid metabolic processGO:00442553230.062
purine ribonucleoside metabolic processGO:00461282410.062
cellular amino acid metabolic processGO:00065201030.062
regulation of sodium ion transportGO:0002028290.062
regulation of chromosome organizationGO:0033044830.061
regulation of cellular amino acid metabolic processGO:000652150.060
cellular ketone metabolic processGO:0042180840.060
peptidyl serine phosphorylationGO:0018105740.059
guanosine containing compound metabolic processGO:19010681440.058
purine containing compound metabolic processGO:00725213110.058
ribonucleoside catabolic processGO:00424542060.058
cellular divalent inorganic cation homeostasisGO:00725031270.058
glycosyl compound catabolic processGO:19016582060.057
aromatic compound catabolic processGO:00194392860.057
dna metabolic processGO:00062593030.056
Mouse
myotube differentiationGO:00149021050.056
regulation of nucleoside metabolic processGO:00091181300.056
heterocycle catabolic processGO:00467002800.054
generation of precursor metabolites and energyGO:00060911030.054
purine nucleotide metabolic processGO:00061633020.054
regulation of histone h3 k9 methylationGO:005157080.053
regulation of cellular amine metabolic processGO:0033238200.053
establishment of protein localization to membraneGO:0090150540.052
ribonucleotide metabolic processGO:00092592910.052
negative regulation of cellular amine metabolic processGO:003323910.051
muscle system processGO:00030121410.051
regulation of neuron projection developmentGO:00109751690.050
peptidyl amino acid modificationGO:00181933360.050
regulation of striated muscle cell differentiationGO:0051153810.049
Mouse
dna modificationGO:0006304500.049
Mouse
ribonucleoside triphosphate metabolic processGO:00091992200.049
dephosphorylationGO:00163111290.047
regulation of histone modificationGO:0031056560.046
organonitrogen compound catabolic processGO:19015652640.046
striated muscle contractionGO:0006941450.046
histone acetylationGO:0016573410.045
stem cell developmentGO:00488642190.045
positive regulation of organelle organizationGO:00106381280.045
cellular carbohydrate metabolic processGO:00442621190.045
inositol phosphate catabolic processGO:007154540.045
protein modification by small protein conjugationGO:00324461870.045
actin filament organizationGO:00070151130.044
organelle localizationGO:00516401790.043
small gtpase mediated signal transductionGO:0007264970.043
regulation of intracellular transportGO:00323861590.043
regulation of reactive oxygen species metabolic processGO:2000377400.043
blood circulationGO:00080151950.043
cytoplasmic transportGO:00164822340.042
cellular response to organonitrogen compoundGO:00714171450.042
positive regulation of histone modificationGO:0031058280.042
carbohydrate derivative catabolic processGO:19011362310.042
regulation of skeletal muscle contraction by calcium ion signalingGO:001472230.042
ventral midline developmentGO:000741840.041
positive regulation of gtp catabolic processGO:0033126850.041
circulatory system processGO:00030131970.041
regulation of purine nucleotide catabolic processGO:00331211220.040
regulation of cellular catabolic processGO:00313292420.040
transmembrane transportGO:00550854120.040
regulation of gtp catabolic processGO:00331241130.040
protein targetingGO:00066051430.040
regulation of ras gtpase activityGO:0032318880.040
gliogenesisGO:00420631410.040
Mouse
myeloid cell differentiationGO:00300992330.039
nucleoside catabolic processGO:00091642060.039
positive regulation of protein modification processGO:00314012990.038
regulation of cellular carbohydrate metabolic processGO:0010675750.038
stem cell maintenanceGO:00198271300.038
cellular response to dna damage stimulusGO:00069742070.038
cation transmembrane transportGO:00986552660.038
regulation of actin filament based processGO:0032970990.038
circadian rhythmGO:00076231140.038
Mouse
multicellular organism growthGO:00352641610.037
response to organonitrogen compoundGO:00102432460.037
regulation of protein localizationGO:00328802310.036
regulation of heart contractionGO:0008016770.036
spleen developmentGO:0048536390.036
peptidyl lysine modificationGO:0018205770.035
cellular response to hormone stimulusGO:00328701500.034
regulation of insulin receptor signaling pathwayGO:0046626210.034
regulation of purine nucleotide metabolic processGO:19005421690.034
protein localization to plasma membraneGO:0072659570.034
amine metabolic processGO:0009308450.034
regulation of organelle organizationGO:00330432890.034
rho protein signal transductionGO:0007266320.033
regulation of protein transportGO:00512231630.033
divalent inorganic cation transportGO:00725111780.033
negative regulation of peptidyl serine phosphorylationGO:0033137100.032
sperm motilityGO:0030317470.032
nucleoside metabolic processGO:00091162460.032
oxidation reduction processGO:00551143420.032
regulation of homeostatic processGO:00328441820.032
positive regulation of gtpase activityGO:0043547850.031
regulation of vesicle mediated transportGO:00606271390.031
protein localization to chromatinGO:007116830.030
Mouse
heart contractionGO:0060047930.030
cell recognitionGO:0008037830.030
regulation of nucleotide metabolic processGO:00061401690.030
energy derivation by oxidation of organic compoundsGO:0015980770.030
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.030
viral gene expressionGO:001908030.030
golgi to endosome transportGO:000689530.029
positive regulation of tor signalingGO:003200830.029
cellular response to cytokine stimulusGO:00713451890.029
mitochondrion distributionGO:004831140.029
posttranscriptional regulation of gene expressionGO:00106081550.029
positive regulation of cellular catabolic processGO:00313311480.029
heart processGO:0003015940.028
microtubule based processGO:00070172360.028
glycerolipid metabolic processGO:00464861220.028
regulation of protein targeting to membraneGO:009031390.028
ribonucleotide catabolic processGO:00092612080.028
regulation of nucleotide catabolic processGO:00308111220.027
negative regulation of cellular response to insulin stimulusGO:1900077160.027
positive regulation of chromosome organizationGO:2001252330.027
mitochondrion organizationGO:00070051340.027
alcohol metabolic processGO:00060661160.026
guanosine containing compound catabolic processGO:19010691440.026
divalent metal ion transportGO:00708381720.026
organic hydroxy compound metabolic processGO:19016152030.026
regulation of chromatin organizationGO:1902275570.026
g protein coupled receptor signaling pathwayGO:00071862430.026
phospholipid metabolic processGO:0006644870.026
phosphorylated carbohydrate dephosphorylationGO:004683840.026
reactive oxygen species metabolic processGO:0072593840.026
internal peptidyl lysine acetylationGO:0018393420.026
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.026
positive regulation of cellular amine metabolic processGO:003324050.025
negative regulation of chromosome organizationGO:2001251300.025
synapse organizationGO:00508081250.025
plasma membrane organizationGO:0007009900.025
response to peptideGO:19016521360.025
nucleotide catabolic processGO:00091662170.025
multicellular organismal signalingGO:0035637910.025
response to peptide hormoneGO:00434341270.025
negative regulation of chromatin modificationGO:1903309190.025
engulfment of apoptotic cellGO:004365230.024
inorganic cation transmembrane transportGO:00986622070.024
negative regulation of cell proliferationGO:00082852960.024
monosaccharide metabolic processGO:00059961060.024
nucleoside phosphate catabolic processGO:19012922220.024
regulation of myotube differentiationGO:0010830620.024
regulation of cellular component biogenesisGO:00440871810.024
vacuole organizationGO:0007033380.023
wound healingGO:00420601570.023
Mouse
negative regulation of glycogen biosynthetic processGO:004571910.023
regulation of establishment of protein localizationGO:00702011810.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
phospholipid dephosphorylationGO:004683960.022
positive regulation of purine nucleotide catabolic processGO:0033123880.022
energy reserve metabolic processGO:0006112390.022
protein localization to membraneGO:00726571080.022
regionalizationGO:00030023370.022
glucose homeostasisGO:00425931280.022
mitotic cytokinesisGO:000028140.021
response to insulinGO:00328681000.021
polyol metabolic processGO:0019751260.021
carbohydrate homeostasisGO:00335001280.021
regenerationGO:0031099380.021
Mouse
gland developmentGO:00487323300.021
homeostasis of number of cellsGO:00488722100.021
polysaccharide metabolic processGO:0005976390.021
protein processingGO:00164851630.021
monosaccharide transportGO:0015749580.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
regulation of intracellular protein transportGO:0033157820.020
ion transmembrane transportGO:00342203610.020
protein localization to organelleGO:00333651850.020
Mouse
regulation of lymphocyte activationGO:00512492400.020
potassium ion transportGO:0006813520.020
negative regulation of stress fiber assemblyGO:005149740.020
calcium ion transportGO:00068161590.019
positive regulation of potassium ion transportGO:004326830.019
cellular glucan metabolic processGO:0006073320.019
maintenance of locationGO:0051235890.019
cellular response to lipidGO:00713961450.019
nucleus organizationGO:0006997450.019
positive regulation of nucleotide metabolic processGO:00459811140.019
male gamete generationGO:00482322850.019
establishment of organelle localizationGO:00516561220.018
neuron apoptotic processGO:00514021420.018
rhythmic processGO:00485111740.018
Mouse
defense response to fungusGO:0050832120.018
regulation of hydrolase activityGO:00513362460.018
response to epidermal growth factorGO:007084940.018
organic cyclic compound catabolic processGO:19013612950.018
regulation of apoptotic signaling pathwayGO:20012331970.017
protein modification by small protein conjugation or removalGO:00706472070.017
organophosphate biosynthetic processGO:00904071220.017
chemotaxisGO:00069352470.017
Fly
dna repairGO:00062811070.017
autophagyGO:0006914450.017
reactive oxygen species biosynthetic processGO:190340980.017
establishment of protein localization to plasma membraneGO:0090002340.017
regulation of secretion by cellGO:19035302490.017
anion transportGO:00068201770.017
positive regulation of homeostatic processGO:0032846640.017
negative regulation of viral transcriptionGO:003289730.017
cellular protein complex assemblyGO:00436231160.017
apoptotic signaling pathwayGO:00971903060.017
peptidyl serine modificationGO:0018209830.017
regulation of carbohydrate biosynthetic processGO:0043255400.016
action potentialGO:0001508780.016
positive regulation of protein catabolic processGO:0045732600.016
cellular component assembly involved in morphogenesisGO:00109271390.016
glycogen metabolic processGO:0005977320.016
positive regulation of apoptotic processGO:00430652170.016
purine nucleotide catabolic processGO:00061952110.016
positive regulation of ras gtpase activityGO:0032320650.016
nitrogen compound transportGO:00717052710.016
negative regulation of insulin receptor signaling pathwayGO:0046627140.016
regulation of reactive oxygen species biosynthetic processGO:190342620.016
cellular response to insulin stimulusGO:0032869780.015
retrograde transport endosome to golgiGO:004214720.015
regulation of carbohydrate metabolic processGO:0006109750.015
innate immune responseGO:00450871570.015
negative regulation of protein transportGO:0051224460.015
negative regulation of nervous system developmentGO:00519611560.015
positive regulation of nucleotide catabolic processGO:0030813880.015
regulation of viral transcriptionGO:004678230.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
neuron deathGO:00709971540.015
regulation of circadian rhythmGO:0042752580.015
Mouse
regulation of peptidyl serine phosphorylationGO:0033135390.015
atp metabolic processGO:0046034750.014
response to inorganic substanceGO:0010035960.014
Mouse
cellular response to organic cyclic compoundGO:0071407870.014
carbohydrate biosynthetic processGO:0016051740.014
small molecule catabolic processGO:0044282710.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
translationGO:0006412930.014
segment specificationGO:0007379150.014
regulation of secretionGO:00510462740.014
positive regulation of hydrolase activityGO:00513451480.014
calcium ion transmembrane transportGO:0070588850.014
negative regulation of glycogen metabolic processGO:007087420.014
neuronal action potentialGO:0019228540.014
organic hydroxy compound catabolic processGO:1901616250.014
response to oxygen levelsGO:0070482620.014
positive regulation of programmed cell deathGO:00430682180.013
hexose metabolic processGO:0019318980.013
histone ubiquitinationGO:0016574100.013
regulation of cell activationGO:00508652890.013
response to oxidative stressGO:00069791230.013
Mouse
carbohydrate metabolic processGO:00059752300.013
leukocyte differentiationGO:00025213420.013
skeletal system developmentGO:00015013560.013
peptidyl lysine methylationGO:0018022290.013
transmission of nerve impulseGO:0019226760.013
regulation of circadian sleep wake cycle sleepGO:004518730.013
protein kinase b signalingGO:0043491740.013
cellular polysaccharide metabolic processGO:0044264380.013
cellular response to oxidative stressGO:0034599760.013
Mouse
regulation of body fluid levelsGO:00508781620.013
macroautophagyGO:0016236210.013
nucleoside phosphate biosynthetic processGO:1901293790.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
vesicle localizationGO:0051648860.013
cellular potassium ion transportGO:0071804430.013
neurotransmitter secretionGO:0007269620.012
regulation of transmembrane transportGO:00347621280.012
regulation of neurotransmitter levelsGO:0001505870.012
response to reactive oxygen speciesGO:0000302560.012
Mouse
rab protein signal transductionGO:003248210.012
inorganic ion transmembrane transportGO:00986602340.012
insulin receptor signaling pathwayGO:0008286490.012
regulation of cell cycleGO:00517262810.012
Mouse
organic anion transportGO:00157111370.012
cellular response to epidermal growth factor stimulusGO:007136440.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
developmental maturationGO:00217001930.012
hematopoietic progenitor cell differentiationGO:00022441430.012
cellular response to biotic stimulusGO:0071216920.012
alcohol catabolic processGO:0046164160.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
internal protein amino acid acetylationGO:0006475420.012
regulation of multi organism processGO:00439001110.012
skin developmentGO:00435882200.012
Mouse
lipid homeostasisGO:0055088630.012
defecationGO:003042110.011
regulation of anatomical structure sizeGO:00900661780.011
spermatogenesisGO:00072832840.011
carbohydrate transportGO:0008643620.011
negative regulation of viral genome replicationGO:0045071100.011
negative regulation of protein targeting to membraneGO:009031510.011
peptidyl threonine phosphorylationGO:0018107310.011
regulation of cell growthGO:0001558910.011
sensory perceptionGO:00076002450.011
heart morphogenesisGO:00030071780.011
regulation of transcription from rna polymerase iii promoterGO:000635920.011
pole plasm assemblyGO:000731520.011
fat cell differentiationGO:00454441600.011
protein polymerizationGO:0051258570.011
regulation of endocytosisGO:0030100690.011
limb developmentGO:00601731660.011
regulation of feeding behaviorGO:006025930.011
cognitionGO:00508901490.011
response to organic cyclic compoundGO:00140701980.011
regulation of rho gtpase activityGO:0032319580.011
hepaticobiliary system developmentGO:0061008670.011
sequestering of calcium ionGO:0051208180.011
endocytosisGO:00068971680.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
protein targeting to membraneGO:0006612200.011
regulation of synaptic plasticityGO:0048167870.011
hexose transportGO:0008645560.011
appendage developmentGO:00487361660.011
liver developmentGO:0001889660.011
cellularizationGO:000734910.011
renal water homeostasisGO:000309170.011
nucleoside monophosphate metabolic processGO:0009123850.010
negative regulation of neuron projection developmentGO:0010977500.010
cellular response to peptide hormone stimulusGO:0071375920.010
syncytium formationGO:0006949430.010
nucleocytoplasmic transportGO:00069131390.010
regulation of tor signalingGO:0032006170.010
water transportGO:0006833120.010
negative regulation of dna templated transcription elongationGO:003278560.010
Mouse
immune effector processGO:00022523210.010
nuclear transportGO:00511691390.010
locomotory behaviorGO:00076261950.010
carbohydrate derivative biosynthetic processGO:19011371830.010
potassium ion transmembrane transportGO:0071805430.010
regulation of translationGO:0006417710.010
regulation of cytokine productionGO:00018172660.010
multicellular organismal movementGO:0050879160.010
organic acid transportGO:00158491010.010
regulation of neurotransmitter transportGO:0051588350.010
cellular response to peptideGO:1901653920.010
regulation of glucose metabolic processGO:0010906600.010
exocytosisGO:00068871210.010

Ezh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.015
neuropathyDOID:87000.011