| negative regulation of molecular function | GO:0044092 | 258 | 0.106 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.090 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.074 | |
| male gamete generation | GO:0048232 | 285 | 0.072 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.071 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.069 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.068 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.066 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.062 | |
| protein ubiquitination | GO:0016567 | 171 | 0.060 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.057 | |
| spermatogenesis | GO:0007283 | 284 | 0.056 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.056 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.056 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.051 | |
| rna interference | GO:0016246 | 2 | 0.051 | |
| rna processing | GO:0006396 | 105 | 0.050 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.049 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.049 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.048 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.047 | |
| amine metabolic process | GO:0009308 | 45 | 0.046 | |
| translation | GO:0006412 | 93 | 0.046 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.045 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.044 | |
| oocyte axis specification | GO:0007309 | 2 | 0.044 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.044 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.044 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.043 | |
| regulation of transposition | GO:0010528 | 2 | 0.043 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.043 | |
| response to osmotic stress | GO:0006970 | 21 | 0.042 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.042 | |
| dna metabolic process | GO:0006259 | 303 | 0.041 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.041 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.041 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.041 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.040 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.039 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.039 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.038 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.037 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.037 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.036 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.035 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.035 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.034 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.034 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.033 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.033 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.033 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.032 | |
| ossification | GO:0001503 | 216 | 0.031 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.031 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.031 | |
| rna splicing | GO:0008380 | 54 | 0.030 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.030 | |
| cytoplasmic translational initiation | GO:0002183 | 3 | 0.029 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.029 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.029 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 2 | 0.028 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.028 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.028 | |
| developmental maturation | GO:0021700 | 193 | 0.028 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.028 | |
| regulation of system process | GO:0044057 | 200 | 0.028 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.027 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.027 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.027 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.027 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.026 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.025 | |
| maintenance of location | GO:0051235 | 89 | 0.025 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.025 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.025 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.025 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.025 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.025 | |
| regulation of cell motility | GO:2000145 | 236 | 0.024 | |
| regulation of circadian sleep wake cycle | GO:0042749 | 3 | 0.024 | |
| pole plasm assembly | GO:0007315 | 2 | 0.024 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.024 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.024 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.024 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.023 | |
| negative regulation of transposition | GO:0010529 | 2 | 0.023 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.023 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.023 | |
| spermine metabolic process | GO:0008215 | 3 | 0.023 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.022 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.022 | |
| muscle tissue development | GO:0060537 | 308 | 0.022 | |
| cation transport | GO:0006812 | 399 | 0.022 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.022 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.022 | |
| ncrna processing | GO:0034470 | 26 | 0.022 | |
| placenta development | GO:0001890 | 140 | 0.022 | |
| cell growth | GO:0016049 | 130 | 0.022 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.022 | |
| translational initiation | GO:0006413 | 24 | 0.021 | |
| regulation of cell migration | GO:0030334 | 219 | 0.021 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.021 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.021 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.021 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.021 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.021 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.021 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.021 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.020 | |
| germ cell development | GO:0007281 | 185 | 0.020 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.020 | |
| positive regulation of striated muscle contraction | GO:0045989 | 3 | 0.020 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.020 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.020 | |
| cellular response to lipid | GO:0071396 | 145 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.020 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.020 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.019 | |
| regulation of chromatin binding | GO:0035561 | 7 | 0.019 | |
| ribosomal small subunit biogenesis | GO:0042274 | 4 | 0.019 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.018 | |
| microtubule based process | GO:0007017 | 236 | 0.018 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.018 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.018 | |
| atp catabolic process | GO:0006200 | 55 | 0.018 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.018 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.018 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.018 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.018 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.017 | |
| positive regulation of homeostatic process | GO:0032846 | 64 | 0.017 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.017 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.017 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.017 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.017 | |
| negative regulation of growth | GO:0045926 | 99 | 0.017 | |
| cellular homeostasis | GO:0019725 | 240 | 0.017 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.017 | |
| protein processing | GO:0016485 | 163 | 0.017 | |
| regulation of protein localization | GO:0032880 | 231 | 0.017 | |
| mitotic chromosome condensation | GO:0007076 | 1 | 0.017 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.017 | |
| innate immune response | GO:0045087 | 157 | 0.017 | |
| muscle system process | GO:0003012 | 141 | 0.017 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.016 | |
| negative regulation of endopeptidase activity | GO:0010951 | 44 | 0.016 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.016 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.016 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.016 | |
| regulation of meiotic cell cycle | GO:0051445 | 34 | 0.016 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.015 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.015 | |
| gene silencing by rna | GO:0031047 | 19 | 0.015 | |
| centrosome separation | GO:0051299 | 4 | 0.015 | |
| regulation of binding | GO:0051098 | 111 | 0.015 | |
| myosin filament assembly | GO:0031034 | 2 | 0.015 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.015 | |
| regulation of cell growth | GO:0001558 | 91 | 0.015 | |
| regulation of cell division | GO:0051302 | 76 | 0.015 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.015 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.015 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.015 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.014 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.014 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.014 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.014 | |
| dendrite development | GO:0016358 | 115 | 0.014 | |
| negative regulation of neuron differentiation | GO:0045665 | 101 | 0.014 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.014 | |
| atp metabolic process | GO:0046034 | 75 | 0.014 | |
| regulation of protein stability | GO:0031647 | 52 | 0.014 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.014 | |
| regulation of defense response | GO:0031347 | 233 | 0.014 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.014 | |
| cell maturation | GO:0048469 | 127 | 0.014 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.014 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.014 | |
| female gamete generation | GO:0007292 | 74 | 0.014 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.014 | |
| synaptic transmission | GO:0007268 | 329 | 0.014 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.014 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.013 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.013 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.013 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.013 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.013 | |
| compound eye development | GO:0048749 | 1 | 0.013 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.013 | |
| negative regulation of binding | GO:0051100 | 39 | 0.013 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.013 | |
| regulation of protein processing | GO:0070613 | 96 | 0.013 | |
| ribonucleoprotein complex disassembly | GO:0032988 | 3 | 0.013 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.013 | |
| muscle cell development | GO:0055001 | 133 | 0.013 | |
| gonad development | GO:0008406 | 141 | 0.013 | |
| muscle contraction | GO:0006936 | 101 | 0.013 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.013 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.013 | |
| regulation of lamellipodium assembly | GO:0010591 | 3 | 0.013 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.012 | |
| activation of adenylate cyclase activity | GO:0007190 | 4 | 0.012 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.012 | |
| locomotory behavior | GO:0007626 | 195 | 0.012 | |
| mapk cascade | GO:0000165 | 281 | 0.012 | |
| mitochondrion organization | GO:0007005 | 134 | 0.012 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.012 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.012 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.012 | |
| endocytosis | GO:0006897 | 168 | 0.012 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.011 | |
| regulation of circadian sleep wake cycle sleep | GO:0045187 | 3 | 0.011 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.011 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.011 | |
| male meiosis | GO:0007140 | 37 | 0.011 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.011 | |
| protein maturation | GO:0051604 | 176 | 0.011 | |
| methylation | GO:0032259 | 134 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.011 | |
| cell division | GO:0051301 | 120 | 0.011 | |
| cellular response to arsenic containing substance | GO:0071243 | 4 | 0.011 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.011 | |
| gtp catabolic process | GO:0006184 | 143 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.011 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.011 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.011 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.011 | |
| positive regulation of necrotic cell death | GO:0010940 | 1 | 0.011 | |
| detection of stimulus | GO:0051606 | 84 | 0.011 | |
| stem cell differentiation | GO:0048863 | 268 | 0.011 | |
| male meiosis i | GO:0007141 | 16 | 0.011 | |
| striated muscle cell development | GO:0055002 | 125 | 0.010 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.010 | |
| negative regulation of peptidase activity | GO:0010466 | 46 | 0.010 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.010 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.010 | |
| spliceosomal complex disassembly | GO:0000390 | 1 | 0.010 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.010 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.010 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.010 | |
| sensory perception | GO:0007600 | 245 | 0.010 | |
