Mus musculus

183 known processes

Igf1r

insulin-like growth factor I receptor

(Aliases: D930020L01,CD221,IGF-1R,A330103N21Rik,hyft)

Igf1r biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of insulin receptor signaling pathwayGO:0046626210.972
hexose metabolic processGO:0019318980.965
Mouse
monosaccharide metabolic processGO:00059961060.942
Mouse
regulation of polysaccharide metabolic processGO:0032881130.931
Mouse
regulation of glucan biosynthetic processGO:001096270.925
Mouse
regulation of glycogen metabolic processGO:0070873130.878
Mouse
glucose metabolic processGO:0006006920.793
Mouse
glycogen metabolic processGO:0005977320.778
Mouse
cellular amino acid metabolic processGO:00065201030.768
positive regulation of glucose metabolic processGO:0010907210.755
Mouse
carbohydrate biosynthetic processGO:0016051740.732
Mouse
cellular polysaccharide metabolic processGO:0044264380.701
Mouse
sensory organ morphogenesisGO:00905962420.695
Zebrafish
generation of precursor metabolites and energyGO:00060911030.688
Mouse
regulation of t cell activationGO:00508631700.681
cellular carbohydrate metabolic processGO:00442621190.671
Mouse
insulin like growth factor receptor signaling pathwayGO:0048009210.663
Human Zebrafish
negative regulation of insulin receptor signaling pathwayGO:0046627140.659
regulation of cellular ketone metabolic processGO:0010565660.650
energy reserve metabolic processGO:0006112390.649
Mouse
gland developmentGO:00487323300.620
polysaccharide biosynthetic processGO:0000271200.619
Mouse
regulation of cellular amino acid metabolic processGO:000652150.612
circadian rhythmGO:00076231140.612
Fly
epidermis developmentGO:00085441870.610
release of cytochrome c from mitochondriaGO:0001836230.592
polysaccharide metabolic processGO:0005976390.575
Mouse
cellular amine metabolic processGO:0044106440.566
regulation of carbohydrate biosynthetic processGO:0043255400.534
Mouse
epithelial tube morphogenesisGO:00605623030.520
response to organic cyclic compoundGO:00140701980.519
Rat Fly
amine metabolic processGO:0009308450.515
regulation of glucose metabolic processGO:0010906600.510
Mouse
leukocyte differentiationGO:00025213420.500
respiratory tube developmentGO:00303231670.488
cellular glucan metabolic processGO:0006073320.480
Mouse
insulin receptor signaling pathwayGO:0008286490.480
Mouse Fly
cation transportGO:00068123990.472
regulation of cell migrationGO:00303342190.467
Human
forebrain developmentGO:00309003020.461
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.455
Human Zebrafish Mouse Fly
multicellular organism growthGO:00352641610.454
Worm Fly
glycogen biosynthetic processGO:0005978140.453
Mouse
ossificationGO:00015032160.445
oxidation reduction processGO:00551143420.433
Mouse
adult behaviorGO:00305341350.426
myotube differentiationGO:00149021050.424
Fly
muscle tissue developmentGO:00605373080.412
negative regulation of glycogen biosynthetic processGO:004571910.406
syncytium formation by plasma membrane fusionGO:0000768420.403
Fly
posttranscriptional regulation of gene expressionGO:00106081550.399
negative regulation of release of cytochrome c from mitochondriaGO:009020160.395
central nervous system neuron differentiationGO:00219531620.386
Zebrafish
wound healingGO:00420601570.385
Zebrafish
gonad developmentGO:00084061410.374
Fly
single organismal cell cell adhesionGO:00163371310.370
glucan biosynthetic processGO:0009250140.369
Mouse
type i pneumocyte differentiationGO:006050970.366
peptidyl amino acid modificationGO:00181933360.364
carbohydrate metabolic processGO:00059752300.359
Mouse Fly
positive regulation of protein serine threonine kinase activityGO:00719021060.353
Human
regulation of generation of precursor metabolites and energyGO:0043467380.350
Mouse
sensory perception of umami tasteGO:005091740.341
response to alkaloidGO:0043279340.341
Fly
positive regulation of cellular amine metabolic processGO:003324050.337
muscle cell differentiationGO:00426922610.335
Fly
positive regulation of map kinase activityGO:0043406840.329
Human
negative regulation of cell proliferationGO:00082852960.327
myelination in peripheral nervous systemGO:0022011190.315
cellular macromolecule catabolic processGO:00442652060.313
skeletal system developmentGO:00015013560.311
establishment or maintenance of cell polarityGO:0007163860.302
Rat
translationGO:0006412930.301
negative regulation of intracellular signal transductionGO:19025321670.298
t cell activationGO:00421102890.296
proteasomal protein catabolic processGO:0010498980.295
regulation of cellular amine metabolic processGO:0033238200.293
lung epithelium developmentGO:0060428370.290
lung cell differentiationGO:0060479300.290
mesodermal cell migrationGO:000807840.285
urogenital system developmentGO:00016552610.285
synapse organizationGO:00508081250.284
skin developmentGO:00435882200.283
regulation of release of cytochrome c from mitochondriaGO:0090199110.279
t cell proliferationGO:00420981200.278
negative regulation of cellular response to insulin stimulusGO:1900077160.276
proteoglycan biosynthetic processGO:0030166200.274
modification dependent protein catabolic processGO:00199411330.269
mitotic cell cycle processGO:19030471590.267
regulation of bindingGO:00510981110.266
regulation of leukocyte proliferationGO:00706631210.266
cellular response to peptide hormone stimulusGO:0071375920.264
Mouse Fly
ameboidal type cell migrationGO:00016671280.263
positive regulation of cellular carbohydrate metabolic processGO:0010676290.261
Mouse
locomotory behaviorGO:00076261950.261
Fly
multi multicellular organism processGO:00447061090.259
Fly
proteolysis involved in cellular protein catabolic processGO:00516031470.259
rhythmic processGO:00485111740.256
Fly
regulation of cellular catabolic processGO:00313292420.254
Worm Fly
negative regulation of cellular protein metabolic processGO:00322692470.250
Human Zebrafish
renal system developmentGO:00720012250.248
glucose transportGO:0015758560.242
connective tissue developmentGO:00614481790.242
regulation of cell motilityGO:20001452360.239
Human
regulation of cell activationGO:00508652890.236
regulation of membrane potentialGO:00423911920.233
organelle assemblyGO:00709251770.232
Worm
retina development in camera type eyeGO:00600411190.231
positive regulation of cell cycleGO:0045787920.231
regulation of organ growthGO:0046620610.229
Fly
striated muscle tissue developmentGO:00147062930.226
action potentialGO:0001508780.226
digestive system developmentGO:00551232000.224
positive regulation of protein phosphorylationGO:00019342420.224
Human
cellular ketone metabolic processGO:0042180840.220
cellular response to insulin stimulusGO:0032869780.220
Mouse Fly
morphogenesis of a branching epitheliumGO:00611381930.219
camera type eye developmentGO:00430102660.212
Zebrafish
cytoplasmic transportGO:00164822340.210
Worm
regulation of cytoplasmic transportGO:19036491120.210
Worm
cerebellar granule cell precursor proliferationGO:0021930100.208
positive regulation of cellular amino acid metabolic processGO:004576430.208
respiratory system developmentGO:00605411900.208
neuronal action potentialGO:0019228540.206
developmental maturationGO:00217001930.205
Fly
response to insulinGO:00328681000.205
Mouse Fly
cellular response to peptideGO:1901653920.202
Mouse Fly
response to radiationGO:00093141650.201
regulation of cellular carbohydrate metabolic processGO:0010675750.200
Mouse
positive regulation of nervous system developmentGO:00519622210.199
steroid metabolic processGO:00082021190.196
Rat
lung developmentGO:00303241640.195
kidney developmentGO:00018222130.193
regulation of carbohydrate metabolic processGO:0006109750.192
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.192
germ line stem cell divisionGO:004207820.192
Fly
negative regulation of cellular amino acid metabolic processGO:004576300.190
organ growthGO:00352651170.190
Fly
regulation of protein catabolic processGO:00421761080.190
regulation of system processGO:00440572000.189
cartilage developmentGO:00512161400.189
response to endoplasmic reticulum stressGO:0034976530.188
response to nutrient levelsGO:00316671090.186
Rat Worm
positive regulation of t cell activationGO:00508701010.185
regulation of steroid biosynthetic processGO:0050810260.185
Rat
type ii pneumocyte differentiationGO:006051070.184
gliogenesisGO:00420631410.182
carbohydrate homeostasisGO:00335001280.182
glucose importGO:0046323320.180
positive regulation of protein kinase activityGO:00458601440.178
Human
immune effector processGO:00022523210.178
intracellular protein transportGO:00068862040.174
Worm
regulation of feeding behaviorGO:006025930.173
Fly
response to organonitrogen compoundGO:00102432460.172
Mouse Fly
glucan metabolic processGO:0044042320.172
Mouse
positive regulation of insulin receptor signaling pathwayGO:004662840.170
positive regulation of cell activationGO:00508671580.169
regulation of secretion by cellGO:19035302490.169
response to peptide hormoneGO:00434341270.167
Mouse Fly
positive regulation of lymphocyte proliferationGO:0050671700.166
regulation of nuclear divisionGO:0051783560.165
apoptotic mitochondrial changesGO:0008637480.165
fat cell differentiationGO:00454441600.165
negative regulation of phosphate metabolic processGO:00459361840.165
cellular lipid metabolic processGO:00442553230.163
glial cell differentiationGO:00100011310.162
cellular response to organonitrogen compoundGO:00714171450.161
Mouse Fly
positive regulation of cell migrationGO:00303351090.158
Human
activation of mapk activityGO:0000187590.157
Human
carbohydrate transportGO:0008643620.157
cellular response to abiotic stimulusGO:0071214560.155
Mouse
positive regulation of kinase activityGO:00336741550.154
Human
regulation of proteolysisGO:00301621640.153
Zebrafish
response to growth factorGO:00708481980.151
Mouse
positive regulation of cell motilityGO:20001471160.151
Human
memoryGO:0007613580.149
regulation of hormone levelsGO:00108172110.149
Rat
hormone secretionGO:00468791280.148
embryonic limb morphogenesisGO:00303261260.147
motor neuron axon guidanceGO:0008045260.147
protein kinase b signalingGO:0043491740.147
energy derivation by oxidation of organic compoundsGO:0015980770.147
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.146
regulation of protein maturationGO:1903317960.146
Zebrafish
regulation of protein bindingGO:0043393600.143
regulation of phospholipase c activityGO:190027430.142
lipid transportGO:0006869980.142
t cell activation involved in immune responseGO:0002286430.140
cell adhesionGO:00071553290.138
monosaccharide transportGO:0015749580.138
cell maturationGO:00484691270.138
Fly
lung epithelial cell differentiationGO:0060487290.137
protein heterotetramerizationGO:005129040.137
positive regulation of cellular catabolic processGO:00313311480.136
formation of radial glial scaffoldsGO:002194340.136
neuron projection guidanceGO:00974851410.136
Fly
macromolecule catabolic processGO:00090572810.136
regulation of kinase activityGO:00435492490.135
Human
exocrine system developmentGO:0035272450.134
positive regulation of cell divisionGO:0051781310.134
cell proliferation in external granule layerGO:0021924100.133
aminoglycan metabolic processGO:0006022340.132
regulation of cellular component biogenesisGO:00440871810.132
Worm
nucleocytoplasmic transportGO:00069131390.132
Worm
positive regulation of lymphocyte activationGO:00512511400.131
cellular metal ion homeostasisGO:00068751510.131
chromatin organizationGO:00063252060.131
neural tube closureGO:0001843900.130
stem cell differentiationGO:00488632680.129
leukocyte proliferationGO:00706611720.128
embryonic appendage morphogenesisGO:00351131260.128
positive regulation of leukocyte proliferationGO:0070665730.127
negative regulation of molecular functionGO:00440922580.125
spermatogenesisGO:00072832840.125
Mouse Fly
circulatory system processGO:00030131970.124
negative regulation of translationGO:0017148220.123
axon guidanceGO:00074111410.123
Fly
regulation of apoptotic signaling pathwayGO:20012331970.122
regulation of bmp signaling pathwayGO:0030510600.122
regulation of fat cell differentiationGO:0045598810.120
reactive nitrogen species metabolic processGO:200105700.119
response to peptideGO:19016521360.119
Mouse Fly
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.118
hexose transportGO:0008645560.118
female sex differentiationGO:0046660840.117
Fly
endocytosisGO:00068971680.117
epithelial cell proliferationGO:00506731740.117
lipid catabolic processGO:0016042690.116
positive regulation of lipid metabolic processGO:0045834400.115
Rat
nucleotide metabolic processGO:00091173320.115
angiogenesisGO:00015252010.115
branching morphogenesis of an epithelial tubeGO:00487541590.114
lipid localizationGO:00108761260.114
Worm
regulation of anatomical structure sizeGO:00900661780.113
Fly
morphogenesis of a branching structureGO:00017632030.113
regulation of cell projection assemblyGO:0060491380.110
modification dependent macromolecule catabolic processGO:00436321330.109
purine containing compound catabolic processGO:00725232130.108
myeloid cell differentiationGO:00300992330.106
regulation of gtp catabolic processGO:00331241130.106
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.106
regulation of cell sizeGO:0008361720.106
Fly
regulation of epithelial cell proliferationGO:00506781410.105
negative regulation of growthGO:0045926990.105
positive regulation of interleukin 5 secretionGO:200066410.104
photoreceptor cell developmentGO:0042461400.104
regulation of glucose transportGO:0010827320.104
hindbrain developmentGO:00309021280.104
regulation of mitochondrion organizationGO:0010821270.103
clara cell differentiationGO:006048640.103
germline stem cell asymmetric divisionGO:009872820.103
Fly
hemostasisGO:0007599780.102
regulation of hydrolase activityGO:00513362460.102
Zebrafish
skeletal system morphogenesisGO:00487052030.101
axonogenesisGO:00074092740.101
Rat Fly
protein targetingGO:00066051430.101
Worm
epithelial cell developmentGO:00020641590.101
Mouse
positive regulation of lipid biosynthetic processGO:0046889180.100
Rat
embryonic skeletal system developmentGO:00487061200.100
regulation of cell cycle processGO:00105641600.099
regulation of glycogen biosynthetic processGO:000597970.099
Mouse
mitotic cell cycleGO:00002781950.099
nuclear importGO:0051170950.099
Worm
cellular protein catabolic processGO:00442571550.098
negative regulation of cellular response to growth factor stimulusGO:0090288460.097
cell fate commitmentGO:00451652100.097
positive regulation of phospholipase activityGO:001051830.097
positive regulation of protein modification processGO:00314012990.096
Human
prostate gland developmentGO:0030850480.096
positive regulation of transferase activityGO:00513471670.096
Human
negative regulation of cellular amine metabolic processGO:003323910.096
axon ensheathmentGO:0008366760.095
apical constrictionGO:000338340.095
neural tube formationGO:00018411080.095
ear developmentGO:00435832000.094
Zebrafish
epithelial cell migrationGO:0010631630.093
negative regulation of hydrolase activityGO:0051346710.093
Zebrafish
neural tube developmentGO:00219151600.093
defecationGO:003042110.093
t cell differentiationGO:00302171740.092
negative regulation of synapse assemblyGO:005196430.092
positive regulation of phospholipase c activityGO:001086320.092
regulation of protein targetingGO:1903533610.091
Worm
forebrain generation of neuronsGO:0021872630.090
nitrogen compound transportGO:00717052710.090
cell proliferation in hindbrainGO:0021534100.090
male gamete generationGO:00482322850.090
Mouse Fly
ras protein signal transductionGO:0007265770.089
regulation of protein serine threonine kinase activityGO:00719001570.089
Human
multi organism reproductive behaviorGO:0044705290.089
Fly
ensheathment of neuronsGO:0007272760.089
schwann cell developmentGO:0014044220.088
positive regulation of purine nucleotide catabolic processGO:0033123880.088
regulation of protein import into nucleusGO:0042306520.087
Worm
positive regulation of hydrolase activityGO:00513451480.087
retina morphogenesis in camera type eyeGO:0060042450.087
lipid biosynthetic processGO:00086101790.086
Rat
neuron maturationGO:0042551290.086
Fly
regulation of nucleotide metabolic processGO:00061401690.086
cognitionGO:00508901490.086
regulation of reactive oxygen species biosynthetic processGO:190342620.086
positive regulation of cell growthGO:0030307330.085
Fly
apoptotic signaling pathwayGO:00971903060.084
regulation of polysaccharide biosynthetic processGO:003288570.084
Mouse
regulation of organelle organizationGO:00330432890.084
intracellular receptor signaling pathwayGO:0030522740.084
purine containing compound metabolic processGO:00725213110.083
purine nucleotide metabolic processGO:00061633020.083
syncytium formationGO:0006949430.083
Fly
erk1 and erk2 cascadeGO:0070371770.083
Mouse
molting cycleGO:0042303900.082
maintenance of locationGO:0051235890.082
Worm
ribonucleoside catabolic processGO:00424542060.082
regulation of cell cycleGO:00517262810.082
regulation of mitotic cell cycleGO:00073461260.081
prostate gland morphogenesisGO:0060512320.081
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.081
nucleoside catabolic processGO:00091642060.081
compound eye developmentGO:004874910.080
negative regulation of epithelial cell proliferationGO:0050680640.080
negative regulation of proteolysisGO:0045861740.080
Zebrafish
cation homeostasisGO:00550802120.080
response to painGO:0048265260.080
peptidyl tyrosine phosphorylationGO:00181081430.079
lymphocyte differentiationGO:00300982420.078
cellular nitrogen compound catabolic processGO:00442702800.078
nucleoside triphosphate catabolic processGO:00091432050.078
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.077
eye photoreceptor cell differentiationGO:0001754410.077
leukocyte activation involved in immune responseGO:00023661260.077
gtp metabolic processGO:00460391440.077
organic hydroxy compound transportGO:0015850930.077
plasma membrane long chain fatty acid transportGO:001591110.076
regulation of transferase activityGO:00513382630.076
Human
negative regulation of mapk cascadeGO:0043409650.076
wnt signaling pathwayGO:00160551880.076
regulation of cellular response to insulin stimulusGO:1900076300.076
nucleoside phosphate metabolic processGO:00067533380.075
mitotic nuclear divisionGO:0007067480.075
cellular response to hormone stimulusGO:00328701500.075
Mouse Fly
filopodium assemblyGO:0046847190.075
negative regulation of protein metabolic processGO:00512482820.074
Human Zebrafish
regulation of lipid metabolic processGO:00192161180.074
Rat
regulation of protein kinase activityGO:00458592320.074
Human
cellular response to growth factor stimulusGO:00713631970.073
Mouse
regulation of lymphocyte activationGO:00512492400.073
ribose phosphate biosynthetic processGO:0046390590.073
nucleobase containing small molecule metabolic processGO:00550863520.072
mapk cascadeGO:00001652810.072
synaptic transmissionGO:00072683290.072
regulation of peptidyl tyrosine phosphorylationGO:0050730930.072
heterocycle catabolic processGO:00467002800.072
negative regulation of endothelial cell migrationGO:001059640.071
anion transportGO:00068201770.071
Mouse
sulfur compound biosynthetic processGO:0044272370.071
neuron migrationGO:00017641220.071
dna metabolic processGO:00062593030.071
Human Rat
guanosine containing compound metabolic processGO:19010681440.071
regulation of cellular protein catabolic processGO:1903362610.071
multicellular organismal signalingGO:0035637910.071
regulation of protein complex assemblyGO:0043254830.071
primary neural tube formationGO:0014020950.070
establishment of protein localization to organelleGO:00725941180.069
Worm
regulation of sequence specific dna binding transcription factor activityGO:00510901060.069
positive regulation of apoptotic signaling pathwayGO:2001235950.068
regulation of wnt signaling pathwayGO:00301111230.068
actin cytoskeleton organizationGO:00300362200.068
regulation of purine nucleotide metabolic processGO:19005421690.068
appendage morphogenesisGO:00351071490.067
hair cycleGO:0042633900.067
regulation of ion transportGO:00432692150.067
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.067
protein localization to nucleusGO:00345041210.067
Worm
single organism cell adhesionGO:00986021560.066
regulation of mapk cascadeGO:00434082480.065
regulation of melanocyte differentiationGO:004563470.065
learning or memoryGO:00076111480.065
lung alveolus developmentGO:0048286450.065
nuclear transportGO:00511691390.064
Worm
response to alcoholGO:0097305480.063
positive regulation of leukocyte differentiationGO:1902107860.063
negative regulation of mitochondrion organizationGO:001082390.063
central nervous system neuron developmentGO:0021954670.063
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.063
fatty acid transmembrane transportGO:190200110.063
response to light stimulusGO:00094161350.063
muscle adaptationGO:0043500390.063
fibroblast proliferationGO:0048144350.062
organic cyclic compound catabolic processGO:19013612950.062
positive regulation of intracellular transportGO:0032388700.062
regulation of glucose importGO:0046324260.061
methylationGO:00322591340.061
neuroblast differentiationGO:001401620.061
divalent metal ion transportGO:00708381720.061
protein import into nucleusGO:0006606950.061
Worm
retinal cone cell developmentGO:004654980.061
peptidyl tyrosine modificationGO:00182121450.060
somitogenesisGO:0001756690.060
hindlimb morphogenesisGO:0035137420.060
prostate glandular acinus morphogenesisGO:006052670.060
regionalizationGO:00030023370.060
Zebrafish
peptide secretionGO:00027901140.060
regulation of secretionGO:00510462740.060
mammary gland epithelium developmentGO:0061180650.060
axis elongation involved in somitogenesisGO:009024540.060
central nervous system projection neuron axonogenesisGO:0021952210.059
neuron projection regenerationGO:0031102140.059
g protein coupled receptor signaling pathwayGO:00071862430.059
cardiac right atrium morphogenesisGO:000321330.059
inorganic ion transmembrane transportGO:00986602340.059
calcium ion homeostasisGO:00550741270.059
reactive oxygen species biosynthetic processGO:190340980.058
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.058
regulation of filopodium assemblyGO:0051489130.058
calcium ion transportGO:00068161590.057
lung lobe morphogenesisGO:006046390.057
glial cell developmentGO:0021782540.057
positive regulation of dna templated transcription elongationGO:003278620.057
transmembrane transportGO:00550854120.057
lipid storageGO:0019915360.056
Worm
negative regulation of apoptotic signaling pathwayGO:20012341040.056
purine ribonucleoside metabolic processGO:00461282410.056
negative regulation of protein processingGO:0010955790.056
Zebrafish
glycoprotein metabolic processGO:00091001160.056
positive regulation of gtp catabolic processGO:0033126850.056
interleukin 5 secretionGO:007260320.055
purine ribonucleotide metabolic processGO:00091502900.055
lymphocyte proliferationGO:00466511640.055
negative regulation of protein modification processGO:00314001630.055
Human
adult locomotory behaviorGO:0008344910.055
bmp signaling pathwayGO:0030509930.055
pancreas developmentGO:0031016570.055
appendage developmentGO:00487361660.054
ribonucleoprotein complex subunit organizationGO:0071826280.054
negative regulation of nervous system developmentGO:00519611560.054
embryonic organ morphogenesisGO:00485622760.054
Zebrafish
dna methylationGO:0006306430.054
cellular response to cytokine stimulusGO:00713451890.053
regulation of map kinase activityGO:00434051200.053
Human
lymphocyte activation involved in immune responseGO:0002285930.053
peptide transportGO:00158331330.053
regulation of body fluid levelsGO:00508781620.053
protein alkylationGO:0008213810.053
regulation of mesenchymal cell proliferation involved in lung developmentGO:200079020.053
receptor mediated endocytosisGO:0006898510.053
positive regulation of growthGO:00459271040.052
Worm Fly
proteoglycan metabolic processGO:0006029380.052
protein maturationGO:00516041760.052
Zebrafish
regulation of protein transportGO:00512231630.052
Worm
regulation of cerebellar granule cell precursor proliferationGO:0021936120.052
protein catabolic processGO:00301632210.052
organelle fissionGO:00482851700.052
olfactory learningGO:000835520.051
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.051
regulation of hormone secretionGO:0046883880.051
forebrain neuron differentiationGO:0021879520.051
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.051
regulation of cell shapeGO:0008360390.051
cerebellum morphogenesisGO:0021587420.051
cytosolic calcium ion homeostasisGO:0051480700.051
cell differentiation in hindbrainGO:0021533240.051
cellular calcium ion homeostasisGO:00068741190.051
digestive tract developmentGO:00485651900.051
reproductive behaviorGO:0019098320.050
Fly
activation of adenylate cyclase activityGO:000719040.050
carbohydrate derivative biosynthetic processGO:19011371830.050
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.050
inorganic cation transmembrane transportGO:00986622070.050
myeloid leukocyte differentiationGO:00025731190.050
regulation of cellular response to growth factor stimulusGO:0090287820.050
protein importGO:00170381010.050
Worm
regulation of peptide hormone secretionGO:0090276750.050
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.049
positive regulation of steroid biosynthetic processGO:001089340.049
Rat
positive regulation of interleukin 13 secretionGO:200066710.049
positive regulation of protein catabolic processGO:0045732600.049
substrate dependent cerebral cortex tangential migrationGO:002182530.049
peptide hormone secretionGO:00300721090.049
positive regulation of gtpase activityGO:0043547850.049
negative regulation of phosphorylationGO:00423261660.049
carbohydrate derivative catabolic processGO:19011362310.048
regulation of steroid metabolic processGO:0019218390.048
Rat
microtubule based processGO:00070172360.048
sensory system developmentGO:004888030.048
blood circulationGO:00080151950.048
germ cell developmentGO:00072811850.048
Fly
muscle system processGO:00030121410.048
regulation of vesicle mediated transportGO:00606271390.048
purine nucleoside metabolic processGO:00422782410.048

Igf1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.825
cancerDOID:16200.652
organ system cancerDOID:005068600.358
disease of metabolismDOID:001466700.132
gastrointestinal system cancerDOID:311900.090
inherited metabolic disorderDOID:65500.080
acquired metabolic diseaseDOID:006015800.057