Mus musculus

5 known processes

Tph2

tryptophan hydroxylase 2

(Aliases: AU043594,Ntph,MGC159133)

Tph2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.116
circulatory system processGO:00030131970.079
Mouse
regulation of system processGO:00440572000.073
Mouse
response to organonitrogen compoundGO:00102432460.070
cellular amino acid metabolic processGO:00065201030.068
Mouse Worm
cellular lipid metabolic processGO:00442553230.066
regulation of secretionGO:00510462740.059
regulation of cellular ketone metabolic processGO:0010565660.057
cellular response to lipidGO:00713961450.054
regulation of neuron differentiationGO:00456642810.054
sensory perceptionGO:00076002450.051
Mouse
placenta developmentGO:00018901400.051
nitrogen compound transportGO:00717052710.050
transmembrane transportGO:00550854120.048
negative regulation of protein metabolic processGO:00512482820.047
norepinephrine transportGO:001587420.046
cation transmembrane transportGO:00986552660.045
muscle contractionGO:00069361010.045
hormone secretionGO:00468791280.044
fatty acid metabolic processGO:00066311210.044
negative regulation of cellular protein metabolic processGO:00322692470.044
regulation of hormone levelsGO:00108172110.044
regulation of secretion by cellGO:19035302490.042
male gamete generationGO:00482322850.042
spermatogenesisGO:00072832840.042
ion transmembrane transportGO:00342203610.041
regulation of circadian sleep wake cycle sleepGO:004518730.041
Fly
organic hydroxy compound transportGO:0015850930.041
lipid biosynthetic processGO:00086101790.039
peptide transportGO:00158331330.039
reactive nitrogen species metabolic processGO:200105700.039
monocarboxylic acid metabolic processGO:00327871910.038
carbohydrate metabolic processGO:00059752300.038
norepinephrine secretionGO:004824320.038
macromolecule catabolic processGO:00090572810.038
inorganic cation transmembrane transportGO:00986622070.038
inorganic ion transmembrane transportGO:00986602340.037
cellular ketone metabolic processGO:0042180840.037
drug catabolic processGO:004273720.036
regulation of response to woundingGO:19030341890.036
purine containing compound metabolic processGO:00725213110.036
nucleobase containing small molecule metabolic processGO:00550863520.035
cellular amine metabolic processGO:0044106440.035
Worm
muscle system processGO:00030121410.034
regulation of cellular amino acid metabolic processGO:000652150.034
negative regulation of phosphorus metabolic processGO:00105631840.034
regulation of adrenergic receptor signaling pathwayGO:007187740.033
nucleotide metabolic processGO:00091173320.033
regulation of norepinephrine secretionGO:001406120.033
cell adhesionGO:00071553290.033
response to peptide hormoneGO:00434341270.033
exogenous drug catabolic processGO:004273810.032
nucleoside phosphate metabolic processGO:00067533380.032
sodium ion transmembrane transportGO:0035725490.031
cellular homeostasisGO:00197252400.031
positive regulation of protein modification processGO:00314012990.031
regulation of protein localizationGO:00328802310.031
cellular response to epinephrine stimulusGO:007187230.031
response to lipopolysaccharideGO:00324961280.031
regulation of inflammatory responseGO:00507271470.031
carbohydrate derivative biosynthetic processGO:19011371830.031
regulation of cellular amine metabolic processGO:0033238200.030
rhythmic processGO:00485111740.030
Fly
protein catabolic processGO:00301632210.030
regulation of hormone secretionGO:0046883880.030
glucose homeostasisGO:00425931280.030
response to molecule of bacterial originGO:00022371430.030
organonitrogen compound catabolic processGO:19015652640.029
multi multicellular organism processGO:00447061090.029
Worm
purine nucleotide metabolic processGO:00061633020.028
regulation of feeding behaviorGO:006025930.028
Worm
chromatin organizationGO:00063252060.027
response to organic cyclic compoundGO:00140701980.027
negative regulation of cellular amino acid metabolic processGO:004576300.027
response to corticosteroneGO:005141210.027
histone modificationGO:00165701590.026
positive regulation of skeletal muscle cell differentiationGO:200101640.026
cellular response to monoamine stimulusGO:007186830.026
developmental maturationGO:00217001930.026
mapk cascadeGO:00001652810.026
regulation of anatomical structure sizeGO:00900661780.026
regulation of reactive oxygen species biosynthetic processGO:190342620.026
cellular chemical homeostasisGO:00550822150.026
response to catecholamineGO:007186940.026
cellular response to organic cyclic compoundGO:0071407870.026
regulation of protein serine threonine kinase activityGO:00719001570.025
ribonucleotide metabolic processGO:00092592910.025
regulation of muscle system processGO:0090257800.025
regulation of hydrolase activityGO:00513362460.025
organic acid biosynthetic processGO:0016053860.025
negative regulation of cell proliferationGO:00082852960.025
negative regulation of phosphorylationGO:00423261660.025
anion transportGO:00068201770.024
positive regulation of cell developmentGO:00107202370.024
negative regulation of molecular functionGO:00440922580.024
organic anion transportGO:00157111370.024
protein maturationGO:00516041760.024
carbohydrate homeostasisGO:00335001280.024
regulation of organelle organizationGO:00330432890.024
ribose phosphate metabolic processGO:00196932910.023
reactive oxygen species biosynthetic processGO:190340980.023
glucose metabolic processGO:0006006920.023
intracellular protein transportGO:00068862040.023
intracellular receptor signaling pathwayGO:0030522740.023
fat cell differentiationGO:00454441600.023
Mouse
forebrain developmentGO:00309003020.023
monosaccharide metabolic processGO:00059961060.022
alpha amino acid catabolic processGO:1901606180.022
positive regulation of defense responseGO:00313491240.022
g protein coupled receptor signaling pathwayGO:00071862430.022
positive regulation of nervous system developmentGO:00519622210.022
organonitrogen compound biosynthetic processGO:19015661920.022
Mouse Worm Fly
cation transportGO:00068123990.022
locomotory behaviorGO:00076261950.021
Mouse
cation homeostasisGO:00550802120.021
carboxylic acid biosynthetic processGO:0046394860.021
negative regulation of phosphate metabolic processGO:00459361840.021
positive regulation of vasoconstrictionGO:004590740.021
cellular amino acid catabolic processGO:0009063250.021
reactive oxygen species metabolic processGO:0072593840.021
purine ribonucleotide metabolic processGO:00091502900.021
maintenance of locationGO:0051235890.020
Worm
regulation of blood pressureGO:0008217930.020
divalent inorganic cation homeostasisGO:00725071380.020
regulation of transferase activityGO:00513382630.020
amide transportGO:00428861380.020
response to peptideGO:19016521360.020
learningGO:0007612980.020
Mouse
response to inorganic substanceGO:0010035960.020
epithelial cell developmentGO:00020641590.020
positive regulation of reactive oxygen species biosynthetic processGO:190342820.020
membrane organizationGO:00610242450.020
camera type eye developmentGO:00430102660.019
Mouse
metal ion homeostasisGO:00550651890.019
positive regulation of response to woundingGO:1903036660.019
cellular response to catecholamine stimulusGO:007187030.019
response to mineralocorticoidGO:005138510.019
hexose metabolic processGO:0019318980.019
regulation of tube sizeGO:0035150570.019
regulation of heart contractionGO:0008016770.019
Mouse
cellular response to hormone stimulusGO:00328701500.019
regulation of circadian sleep wake cycleGO:004274930.019
Fly
protein targetingGO:00066051430.019
negative regulation of protein modification processGO:00314001630.019
response to acid chemicalGO:00011011110.018
divalent inorganic cation transportGO:00725111780.018
learning or memoryGO:00076111480.018
Mouse
blood circulationGO:00080151950.018
Mouse
regulation of ion transmembrane transportGO:00347651190.018
regulation of blood vessel sizeGO:0050880560.018
regulation of fat cell differentiationGO:0045598810.018
Mouse
regulation of kinase activityGO:00435492490.018
regulation of cell projection organizationGO:00313442060.018
cellular response to dna damage stimulusGO:00069742070.018
epinephrine transportGO:004824110.018
regulation of protein kinase activityGO:00458592320.018
organic cyclic compound catabolic processGO:19013612950.018
regulation of cell cycleGO:00517262810.018
negative regulation of intracellular signal transductionGO:19025321670.018
monocarboxylic acid biosynthetic processGO:0072330610.018
peptidyl amino acid modificationGO:00181933360.018
negative regulation of cellular amine metabolic processGO:003323910.018
regulation of mapk cascadeGO:00434082480.017
aromatic compound catabolic processGO:00194392860.017
urogenital system developmentGO:00016552610.017
response to light stimulusGO:00094161350.017
cytoplasmic transportGO:00164822340.017
epidermis developmentGO:00085441870.017
developmental growth involved in morphogenesisGO:00605601380.017
regulation of protein transportGO:00512231630.017
regulation of peptide transportGO:0090087910.017
regulation of establishment of protein localizationGO:00702011810.017
negative regulation of peptidyl serine phosphorylationGO:0033137100.017
skeletal muscle organ developmentGO:00605381630.017
detection of stimulusGO:0051606840.017
cellular nitrogen compound catabolic processGO:00442702800.017
cellular response to lipopolysaccharideGO:0071222770.017
inflammatory responseGO:00069542440.017
regulation of androgen receptor signaling pathwayGO:006076530.017
monoamine transportGO:0015844330.017
striated muscle contractionGO:0006941450.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
purine nucleoside metabolic processGO:00422782410.017
regulation of purine nucleotide metabolic processGO:19005421690.017
peptide secretionGO:00027901140.016
negative regulation of cellular component organizationGO:00511291940.016
response to steroid hormoneGO:0048545560.016
nucleoside metabolic processGO:00091162460.016
regulation of blood circulationGO:1903522930.016
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.016
insulin secretionGO:0030073890.016
divalent metal ion transportGO:00708381720.016
cellular response to cytokine stimulusGO:00713451890.016
axonogenesisGO:00074092740.016
heart contractionGO:0060047930.016
Mouse
regulation of defense responseGO:00313472330.016
small molecule biosynthetic processGO:00442831320.016
embryonic placenta developmentGO:0001892980.016
striated muscle tissue developmentGO:00147062930.016
cellular protein complex assemblyGO:00436231160.016
muscle tissue developmentGO:00605373080.015
apoptotic signaling pathwayGO:00971903060.015
hematopoietic progenitor cell differentiationGO:00022441430.015
multicellular organismal signalingGO:0035637910.015
heart processGO:0003015940.015
Mouse
cell growthGO:00160491300.015
nucleotide catabolic processGO:00091662170.015
peptide hormone secretionGO:00300721090.015
cellular response to molecule of bacterial originGO:0071219830.015
organelle localizationGO:00516401790.015
regulation of protein catabolic processGO:00421761080.015
negative regulation of protein phosphorylationGO:00019331260.015
negative regulation of hormone secretionGO:0046888200.015
synaptic transmissionGO:00072683290.015
Mouse
heterocycle catabolic processGO:00467002800.015
defense response to other organismGO:00985421970.015
nuclear divisionGO:00002801580.015
covalent chromatin modificationGO:00165691630.015
purine ribonucleoside catabolic processGO:00461302050.015
positive regulation of sodium ion transmembrane transportGO:190230740.014
nucleotide biosynthetic processGO:0009165780.014
organelle fissionGO:00482851700.014
regulation of neurotransmitter levelsGO:0001505870.014
positive regulation of neuron differentiationGO:00456661410.014
positive regulation of cell deathGO:00109422240.014
fertilizationGO:00095661270.014
amine metabolic processGO:0009308450.014
Worm
negative regulation of blood pressureGO:0045776220.014
ossificationGO:00015032160.014
chromatin modificationGO:00165681870.014
tissue remodelingGO:00487711020.014
Mouse
renal system developmentGO:00720012250.014
circadian regulation of gene expressionGO:0032922480.014
chemotaxisGO:00069352470.014
regulation of apoptotic signaling pathwayGO:20012331970.014
lipid transportGO:0006869980.014
response to glucagonGO:003376230.014
nucleocytoplasmic transportGO:00069131390.013
response to radiationGO:00093141650.013
positive regulation of programmed cell deathGO:00430682180.013
regulation of ion transportGO:00432692150.013
response to oxygen levelsGO:0070482620.013
blood vessel morphogenesisGO:00485142850.013
nuclear transportGO:00511691390.013
cytokine productionGO:00018163190.013
microtubule based processGO:00070172360.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
catecholamine transportGO:0051937210.013
organelle assemblyGO:00709251770.013
histone acetylationGO:0016573410.013
regulation of circadian rhythmGO:0042752580.013
Fly
alpha amino acid metabolic processGO:1901605590.012
Mouse Worm
negative regulation of secretion by cellGO:1903531540.012
photoreceptor cell differentiationGO:0046530520.012
Mouse
regulation of reactive oxygen species metabolic processGO:2000377400.012
anatomical structure homeostasisGO:00602491450.012
potassium ion transportGO:0006813520.012
circadian rhythmGO:00076231140.012
Fly
response to monoamineGO:007186740.012
cellular response to organonitrogen compoundGO:00714171450.012
serotonin uptakeGO:005161030.012
circadian sleep wake cycleGO:004274550.012
Fly
l glutamate uptake involved in synaptic transmissionGO:005193530.012
regulation of transmembrane transportGO:00347621280.012
nucleoside phosphate catabolic processGO:19012922220.012
regulation of vasculature developmentGO:1901342880.012
positive regulation of phospholipase c activityGO:001086320.012
regulation of protein maturationGO:1903317960.012
response to vitamin aGO:003318910.012
vasodilationGO:0042311280.012
response to nutrient levelsGO:00316671090.012
small gtpase mediated signal transductionGO:0007264970.012
modification dependent protein catabolic processGO:00199411330.012
regulation of cell migrationGO:00303342190.012
positive regulation of mapk cascadeGO:00434101700.012
cellular response to biotic stimulusGO:0071216920.012
regulation of cellular catabolic processGO:00313292420.012
neurotransmitter uptakeGO:0001504140.012
calcium ion homeostasisGO:00550741270.012
regulation of presynaptic membrane organizationGO:190162930.012
protein modification by small protein conjugation or removalGO:00706472070.012
regulation of sodium ion transmembrane transportGO:190230590.012
protein localization to organelleGO:00333651850.012
cellular macromolecule catabolic processGO:00442652060.012
response to oxidative stressGO:00069791230.012
female sex differentiationGO:0046660840.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
peptidyl cysteine modificationGO:001819880.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
positive regulation of nitric oxide synthase activityGO:005100020.011
regulation of neuron projection developmentGO:00109751690.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
regulation of muscle contractionGO:0006937490.011
cyclic nucleotide metabolic processGO:0009187590.011
regulation of dna damage checkpointGO:200000130.011
negative regulation of secretionGO:0051048610.011
establishment of protein localization to organelleGO:00725941180.011
respiratory tube developmentGO:00303231670.011
organic acid transportGO:00158491010.011
purine nucleoside catabolic processGO:00061522050.011
organophosphate biosynthetic processGO:00904071220.011
cellular response to peptideGO:1901653920.011
positive regulation of transferase activityGO:00513471670.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
blastocyst growthGO:0001832230.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.011
mitochondrion distributionGO:004831140.011
protein ubiquitinationGO:00165671710.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
endocrine system developmentGO:0035270980.011
organophosphate catabolic processGO:00464342320.011
response to temperature stimulusGO:0009266550.011
ubiquitin dependent protein catabolic processGO:00065111290.011
glycosyl compound metabolic processGO:19016572460.011
regulation of anion transportGO:0044070270.011
l amino acid transportGO:0015807320.011
anatomical structure maturationGO:0071695490.011
nucleoside catabolic processGO:00091642060.011
generation of precursor metabolites and energyGO:00060911030.011
cellular ion homeostasisGO:00068731650.011
cellular protein catabolic processGO:00442571550.011
intracellular steroid hormone receptor signaling pathwayGO:0030518290.011
negative regulation of androgen receptor signaling pathwayGO:006076630.011
peptidyl serine phosphorylationGO:0018105740.011
protein modification by small protein conjugationGO:00324461870.011
cellular response to acid chemicalGO:0071229680.011
developmental cell growthGO:0048588840.011
nucleoside monophosphate metabolic processGO:0009123850.011
positive regulation of cellular amine metabolic processGO:003324050.011
response to drugGO:0042493750.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
carbohydrate derivative catabolic processGO:19011362310.011
response to extracellular stimulusGO:00099911270.011
liver developmentGO:0001889660.011
regulation of cell cycle processGO:00105641600.011
regulation of cell activationGO:00508652890.011
regulation of peptide secretionGO:0002791770.011
cellular component assembly involved in morphogenesisGO:00109271390.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
fatty acid biosynthetic processGO:0006633410.011
respiratory system developmentGO:00605411900.011
purine ribonucleoside metabolic processGO:00461282410.011
innate immune responseGO:00450871570.011
small molecule catabolic processGO:0044282710.011
calcium ion transmembrane transportGO:0070588850.010
positive regulation of fatty acid oxidationGO:004632140.010
hormone metabolic processGO:0042445860.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
regulation of cell adhesionGO:00301551540.010
pancreas developmentGO:0031016570.010
leukocyte mediated immunityGO:00024431740.010
feeding behaviorGO:0007631620.010
Mouse Worm
cytosolic calcium ion homeostasisGO:0051480700.010
regulation of membrane potentialGO:00423911920.010
regulation of cytokine productionGO:00018172660.010
ribonucleoside catabolic processGO:00424542060.010
cellular calcium ion homeostasisGO:00068741190.010
transmission of nerve impulseGO:0019226760.010
cellular metal ion homeostasisGO:00068751510.010
carbohydrate biosynthetic processGO:0016051740.010
positive regulation of monooxygenase activityGO:003277020.010
vascular process in circulatory systemGO:0003018620.010
regulation of chromatin silencingGO:003193520.010
regulation of action potentialGO:009890040.010
purine nucleotide catabolic processGO:00061952110.010
icosanoid metabolic processGO:0006690330.010
myosin filament assemblyGO:003103420.010
leukocyte differentiationGO:00025213420.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
carboxylic acid transportGO:00469421000.010
epinephrine secretionGO:004824210.010
carboxylic acid catabolic processGO:0046395510.010
response to insulinGO:00328681000.010
response to hyperoxiaGO:005509320.010
negative regulation of fat cell differentiationGO:0045599360.010
purine containing compound biosynthetic processGO:0072522700.010

Tph2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
nervous system diseaseDOID:86300.065
central nervous system diseaseDOID:33100.023
musculoskeletal system diseaseDOID:1700.015
neurodegenerative diseaseDOID:128900.013
connective tissue diseaseDOID:6500.012
sensory system diseaseDOID:005015500.011