IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gtl3

gene trap locus 3

(Aliases: T10-2A2,AL024127,2600014O15Rik)

Ensembl: ENSMUSG00000031796
Entrez: 14894
UniProtKB: Q8BTU1

Process Predictions
Disease Predictions

Gtl3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cilium morphogenesis	GO:0060271	102	0.710
cilium assembly	GO:0042384	81	0.574
organelle assembly	GO:0070925	177	0.111
cellular response to dna damage stimulus	GO:0006974	207	0.102
intraciliary transport	GO:0042073	9	0.098
regulation of cell cycle	GO:0051726	281	0.093
cellular component assembly involved in morphogenesis	GO:0010927	139	0.088
microtubule cytoskeleton organization	GO:0000226	157	0.068
negative regulation of cell proliferation	GO:0008285	296	0.065
aromatic compound catabolic process	GO:0019439	286	0.063
organic cyclic compound catabolic process	GO:1901361	295	0.062
dna metabolic process	GO:0006259	303	0.062
dna repair	GO:0006281	107	0.059
gene silencing by mirna	GO:0035195	10	0.056
glycosyl compound metabolic process	GO:1901657	246	0.055
rna processing	GO:0006396	105	0.050
protein localization to organelle	GO:0033365	185	0.049
peptidyl amino acid modification	GO:0018193	336	0.047
regulation of cell cycle process	GO:0010564	160	0.047
organonitrogen compound catabolic process	GO:1901565	264	0.047
heterocycle catabolic process	GO:0046700	280	0.046
cell division	GO:0051301	120	0.045
cytoskeleton dependent intracellular transport	GO:0030705	50	0.044
cellular nitrogen compound catabolic process	GO:0044270	280	0.042
digestive system development	GO:0055123	200	0.041
regulation of epithelial cell proliferation	GO:0050678	141	0.041
nucleotide metabolic process	GO:0009117	332	0.041
nucleoside phosphate catabolic process	GO:1901292	222	0.039
regulation of cellular ketone metabolic process	GO:0010565	66	0.039
nucleoside phosphate metabolic process	GO:0006753	338	0.039
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.039
intracellular protein transport	GO:0006886	204	0.038
mrna metabolic process	GO:0016071	84	0.038
guanosine containing compound catabolic process	GO:1901069	144	0.038
ribonucleoside metabolic process	GO:0009119	245	0.038
nucleotide catabolic process	GO:0009166	217	0.038
carbohydrate derivative catabolic process	GO:1901136	231	0.038
ribonucleoside catabolic process	GO:0042454	206	0.036
purine nucleotide metabolic process	GO:0006163	302	0.036
regulation of organelle organization	GO:0033043	289	0.036
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.035
methylation	GO:0032259	134	0.035
urogenital system development	GO:0001655	261	0.035
apoptotic signaling pathway	GO:0097190	306	0.035
renal system development	GO:0072001	225	0.035
glycosyl compound catabolic process	GO:1901658	206	0.034
appendage development	GO:0048736	166	0.034
regulation of mitotic cell cycle	GO:0007346	126	0.034
rna splicing	GO:0008380	54	0.034
cytoplasmic transport	GO:0016482	234	0.034
kidney development	GO:0001822	213	0.034
organophosphate catabolic process	GO:0046434	232	0.033
establishment of organelle localization	GO:0051656	122	0.033
negative regulation of multi organism process	GO:0043901	68	0.033
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.033
posttranscriptional regulation of gene expression	GO:0010608	155	0.032
mitotic cell cycle	GO:0000278	195	0.032
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.032
digestive tract development	GO:0048565	190	0.031
digestive tract morphogenesis	GO:0048546	147	0.030
regulation of cellular amino acid metabolic process	GO:0006521	5	0.030
germ cell development	GO:0007281	185	0.030
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.030
gastrulation	GO:0007369	116	0.030
microtubule based process	GO:0007017	236	0.030
regulation of cellular amine metabolic process	GO:0033238	20	0.029
cellular amino acid metabolic process	GO:0006520	103	0.029
purine nucleoside catabolic process	GO:0006152	205	0.029
mitotic cell cycle process	GO:1903047	159	0.029
protein modification by small protein conjugation	GO:0032446	187	0.029
membrane organization	GO:0061024	245	0.029
epithelial cell proliferation	GO:0050673	174	0.029
skin development	GO:0043588	220	0.028
purine containing compound catabolic process	GO:0072523	213	0.028
purine containing compound metabolic process	GO:0072521	311	0.028
nucleobase containing small molecule metabolic process	GO:0055086	352	0.028
response to radiation	GO:0009314	165	0.028
nuclear division	GO:0000280	158	0.028
purine nucleoside metabolic process	GO:0042278	241	0.028
skeletal system development	GO:0001501	356	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.028
nucleoside triphosphate catabolic process	GO:0009143	205	0.028
mrna processing	GO:0006397	63	0.028
camera type eye development	GO:0043010	266	0.028
response to transforming growth factor beta	GO:0071559	88	0.028
smoothened signaling pathway	GO:0007224	105	0.026
ribonucleotide catabolic process	GO:0009261	208	0.026
nucleoside catabolic process	GO:0009164	206	0.026
purine nucleotide catabolic process	GO:0006195	211	0.026
hematopoietic progenitor cell differentiation	GO:0002244	143	0.025
protein modification by small protein conjugation or removal	GO:0070647	207	0.025
male gamete generation	GO:0048232	285	0.025
nucleoside metabolic process	GO:0009116	246	0.025
meiotic nuclear division	GO:0007126	115	0.025
cellular response to growth factor stimulus	GO:0071363	197	0.025
gtp metabolic process	GO:0046039	144	0.025
regulation of mapk cascade	GO:0043408	248	0.024
regionalization	GO:0003002	337	0.024
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.024
cell fate commitment	GO:0045165	210	0.024
purine ribonucleotide catabolic process	GO:0009154	208	0.023
ribonucleotide metabolic process	GO:0009259	291	0.023
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.023
nucleotide excision repair	GO:0006289	13	0.023
histone modification	GO:0016570	159	0.023
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.023
ribose phosphate metabolic process	GO:0019693	291	0.023
purine ribonucleoside catabolic process	GO:0046130	205	0.023
positive regulation of protein modification process	GO:0031401	299	0.022
amine metabolic process	GO:0009308	45	0.022
wnt signaling pathway	GO:0016055	188	0.022
regulation of hydrolase activity	GO:0051336	246	0.021
cell adhesion	GO:0007155	329	0.021
regulation of apoptotic signaling pathway	GO:2001233	197	0.021
establishment of protein localization to organelle	GO:0072594	118	0.021
regulation of nuclear division	GO:0051783	56	0.021
microtubule based transport	GO:0010970	50	0.021
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	57	0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.020
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.020
double strand break repair	GO:0006302	48	0.020
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.020
cellular ketone metabolic process	GO:0042180	84	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.020
gtp catabolic process	GO:0006184	143	0.020
regulation of cell activation	GO:0050865	289	0.020
microtubule based movement	GO:0007018	84	0.020
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.019
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.019
negative regulation of cellular protein metabolic process	GO:0032269	247	0.019
nuclear transport	GO:0051169	139	0.019
regulation of cellular catabolic process	GO:0031329	242	0.019
response to growth factor	GO:0070848	198	0.019
substantia nigra development	GO:0021762	2	0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.019
dna recombination	GO:0006310	92	0.019
carbohydrate derivative biosynthetic process	GO:1901137	183	0.018
retina development in camera type eye	GO:0060041	119	0.018
positive regulation of programmed cell death	GO:0043068	218	0.018
organelle fission	GO:0048285	170	0.018
spermatogenesis	GO:0007283	284	0.018
organelle localization	GO:0051640	179	0.018
immune effector process	GO:0002252	321	0.018
asymmetric stem cell division	GO:0098722	3	0.018
chemotaxis	GO:0006935	247	0.018
regulation of nucleotide catabolic process	GO:0030811	122	0.018
regulation of lymphocyte activation	GO:0051249	240	0.018
deoxyribose phosphate metabolic process	GO:0019692	9	0.018
production of molecular mediator of immune response	GO:0002440	103	0.018
macromolecule methylation	GO:0043414	120	0.018
epidermis development	GO:0008544	187	0.018
single organism nuclear import	GO:1902593	95	0.017
regulation of protein transport	GO:0051223	163	0.017
negative regulation of cell cycle	GO:0045786	123	0.017
cellular amine metabolic process	GO:0044106	44	0.017
positive regulation of cell development	GO:0010720	237	0.017
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.017
purine ribonucleotide metabolic process	GO:0009150	290	0.017
negative regulation of protein metabolic process	GO:0051248	282	0.016
negative regulation of mitotic cell cycle phase transition	GO:1901991	45	0.016
protein import	GO:0017038	101	0.016
positive regulation of protein phosphorylation	GO:0001934	242	0.016
positive regulation of growth	GO:0045927	104	0.016
leukocyte proliferation	GO:0070661	172	0.016
homeostasis of number of cells	GO:0048872	210	0.016
guanosine containing compound metabolic process	GO:1901068	144	0.016
positive regulation of protein kinase activity	GO:0045860	144	0.016
hematopoietic stem cell differentiation	GO:0060218	8	0.016
small gtpase mediated signal transduction	GO:0007264	97	0.015
intrinsic apoptotic signaling pathway	GO:0097193	132	0.015
organophosphate biosynthetic process	GO:0090407	122	0.015
transmembrane transport	GO:0055085	412	0.015
nitrogen compound transport	GO:0071705	271	0.015
positive regulation of cell death	GO:0010942	224	0.015
regulation of multi organism process	GO:0043900	111	0.015
regulation of cell cycle phase transition	GO:1901987	77	0.015
cytokine production	GO:0001816	319	0.015
phagosome maturation	GO:0090382	4	0.015
fat cell differentiation	GO:0045444	160	0.015
covalent chromatin modification	GO:0016569	163	0.014
response to organic cyclic compound	GO:0014070	198	0.014
extracellular matrix organization	GO:0030198	147	0.014
cell type specific apoptotic process	GO:0097285	268	0.014
transmission of nerve impulse	GO:0019226	76	0.014
protein ubiquitination	GO:0016567	171	0.014
negative regulation of epithelial cell proliferation	GO:0050680	64	0.014
regulation of nucleoside metabolic process	GO:0009118	130	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
neuron projection guidance	GO:0097485	141	0.014
cellular response to organic cyclic compound	GO:0071407	87	0.014
tube formation	GO:0035148	140	0.014
protein localization to nucleus	GO:0034504	121	0.014
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.014
regulation of purine nucleotide catabolic process	GO:0033121	122	0.014
protein maturation	GO:0051604	176	0.014
dna templated transcription termination	GO:0006353	4	0.013
positive regulation of kinase activity	GO:0033674	155	0.013
regulation of protein serine threonine kinase activity	GO:0071900	157	0.013
nucleocytoplasmic transport	GO:0006913	139	0.013
peptidyl lysine modification	GO:0018205	77	0.013
nuclear import	GO:0051170	95	0.013
adult behavior	GO:0030534	135	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
immunoglobulin production	GO:0002377	73	0.013
somatic cell dna recombination	GO:0016444	51	0.013
regulation of protein stability	GO:0031647	52	0.013
negative regulation of cell cycle process	GO:0010948	69	0.013
sensory organ morphogenesis	GO:0090596	242	0.013
terminal button organization	GO:0072553	3	0.013
leukocyte mediated immunity	GO:0002443	174	0.013
protein import into nucleus	GO:0006606	95	0.013
mitotic cytokinesis	GO:0000281	4	0.013
forebrain development	GO:0030900	302	0.012
meiotic cell cycle	GO:0051321	122	0.012
positive regulation of transferase activity	GO:0051347	167	0.012
positive regulation of map kinase activity	GO:0043406	84	0.012
negative regulation of organelle organization	GO:0010639	90	0.012
cellular homeostasis	GO:0019725	240	0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.012
ncrna 3 end processing	GO:0043628	2	0.012
regulation of translation	GO:0006417	71	0.012
t cell differentiation	GO:0030217	174	0.012
response to inorganic substance	GO:0010035	96	0.012
cation transmembrane transport	GO:0098655	266	0.012
somatic diversification of immune receptors	GO:0002200	53	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
photoreceptor cell differentiation	GO:0046530	52	0.012
regulation of transferase activity	GO:0051338	263	0.012
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.012
positive regulation of nucleoside metabolic process	GO:0045979	91	0.012
negative regulation of cell cycle phase transition	GO:1901988	48	0.012
cardiac muscle tissue development	GO:0048738	130	0.012
positive regulation of cellular catabolic process	GO:0031331	148	0.012
regulation of kinase activity	GO:0043549	249	0.012
positive regulation of hydrolase activity	GO:0051345	148	0.012
negative regulation of cellular component organization	GO:0051129	194	0.012
response to light stimulus	GO:0009416	135	0.012
regulation of intracellular transport	GO:0032386	159	0.012
lateral inhibition	GO:0046331	1	0.012
b cell activation	GO:0042113	161	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.011
regulation of protein localization	GO:0032880	231	0.011
chromatin organization	GO:0006325	206	0.011
cell activation involved in immune response	GO:0002263	126	0.011
t cell activation	GO:0042110	289	0.011
leukocyte differentiation	GO:0002521	342	0.011
hypoxia inducible factor 1alpha signaling pathway	GO:0097411	2	0.011
axonogenesis	GO:0007409	274	0.011
negative regulation of cellular response to growth factor stimulus	GO:0090288	46	0.011
muscle tissue development	GO:0060537	308	0.011
regulation of protein kinase activity	GO:0045859	232	0.011
nucleoside phosphate biosynthetic process	GO:1901293	79	0.011
regulation of mrna metabolic process	GO:1903311	43	0.011
myeloid cell differentiation	GO:0030099	233	0.011
positive regulation of mapk cascade	GO:0043410	170	0.011
mrna splicing via spliceosome	GO:0000398	43	0.011
immunoglobulin mediated immune response	GO:0016064	69	0.011
regulation of chromatin silencing	GO:0031935	2	0.011
protein targeting	GO:0006605	143	0.011
neuronal action potential	GO:0019228	54	0.011
regulation of cell division	GO:0051302	76	0.011
cellular response to lipid	GO:0071396	145	0.011
synaptic transmission	GO:0007268	329	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
mapk cascade	GO:0000165	281	0.011
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	51	0.011
regulation of map kinase activity	GO:0043405	120	0.011
asymmetric neuroblast division	GO:0055059	1	0.010
purine ribonucleoside metabolic process	GO:0046128	241	0.010
positive regulation of apoptotic process	GO:0043065	217	0.010
protein processing	GO:0016485	163	0.010
somatic recombination of immunoglobulin gene segments	GO:0016447	42	0.010
bone development	GO:0060348	120	0.010
negative regulation of immune system process	GO:0002683	209	0.010
regulation of leukocyte differentiation	GO:1902105	159	0.010
multicellular organismal signaling	GO:0035637	91	0.010
organonitrogen compound biosynthetic process	GO:1901566	192	0.010
gene silencing	GO:0016458	38	0.010
regulation of establishment of protein localization	GO:0070201	181	0.010
g protein coupled receptor signaling pathway	GO:0007186	243	0.010
lymphocyte mediated immunity	GO:0002449	139	0.010
limb development	GO:0060173	166	0.010
lymphocyte activation involved in immune response	GO:0002285	93	0.010
regulation of cell projection organization	GO:0031344	206	0.010
negative regulation of mitotic cell cycle	GO:0045930	58	0.010
response to oxidative stress	GO:0006979	123	0.010
regulation of cytokine production	GO:0001817	266	0.010
multicellular organism growth	GO:0035264	161	0.010

Gtl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.023
nervous system disease	DOID:863	0.023
sensory system disease	DOID:0050155	0.015
eye and adnexa disease	DOID:1492	0.015
retinal disease	DOID:5679	0.015
eye disease	DOID:5614	0.015

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