Mus musculus

5 known processes

Akr1c21

aldo-keto reductase family 1, member C21

(Aliases: MGC102401,AI315367,9430025F20Rik)

Akr1c21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
progesterone metabolic processGO:004244840.568
Human
anion transportGO:00068201770.496
lipid biosynthetic processGO:00086101790.475
Human Mouse
amino acid transmembrane transportGO:0003333370.434
monocarboxylic acid metabolic processGO:00327871910.419
Human
organic acid transportGO:00158491010.413
response to phenylpropanoidGO:0080184220.371
regulation of hormone levelsGO:00108172110.351
Human
organic anion transportGO:00157111370.312
anion transmembrane transportGO:0098656710.312
negative regulation of iron ion transportGO:003475710.292
organic hydroxy compound metabolic processGO:19016152030.282
Human
dibenzo p dioxin metabolic processGO:001889410.275
carboxylic acid transportGO:00469421000.272
cellular ketone metabolic processGO:0042180840.254
Human
carnitine transmembrane transportGO:190260330.250
response to stilbenoidGO:0035634220.246
carnitine transportGO:001587930.208
hormone metabolic processGO:0042445860.206
Human
carboxylic acid biosynthetic processGO:0046394860.200
Human
cellular lipid metabolic processGO:00442553230.189
Human
steroid metabolic processGO:00082021190.187
Human Mouse
cellular response to lipidGO:00713961450.177
Human
response to organic cyclic compoundGO:00140701980.165
Human
c21 steroid hormone biosynthetic processGO:000670030.163
amino acid transportGO:0006865610.156
benzene containing compound metabolic processGO:004253750.146
cellular response to inorganic substanceGO:0071241370.144
Human
nitrogen compound transportGO:00717052710.140
amino acid betaine transportGO:001583830.136
small molecule biosynthetic processGO:00442831320.132
Human
oxidation reduction processGO:00551143420.129
cellular amino acid metabolic processGO:00065201030.122
response to organonitrogen compoundGO:00102432460.113
progesterone biosynthetic processGO:000670110.112
regulation of secretionGO:00510462740.110
glycerolipid metabolic processGO:00464861220.108
monocarboxylic acid transportGO:0015718440.105
regulation of defense responseGO:00313472330.104
cellular alcohol metabolic processGO:004410730.103
cellular response to hormone stimulusGO:00328701500.102
Human
vitamin metabolic processGO:0006766230.095
Human
alcohol metabolic processGO:00060661160.087
Human
amino acid betaine metabolic processGO:000657770.085
skin developmentGO:00435882200.084
Human
androgen metabolic processGO:0008209110.084
Human
regulation of cellular ketone metabolic processGO:0010565660.082
Human
androgen biosynthetic processGO:000670240.080
Human
response to peptide hormoneGO:00434341270.078
amine metabolic processGO:0009308450.074
cofactor metabolic processGO:0051186800.074
Human
ion transmembrane transportGO:00342203610.073
fatty acid metabolic processGO:00066311210.070
Human
steroid biosynthetic processGO:0006694470.069
Human Mouse
fat soluble vitamin biosynthetic processGO:004236240.068
protein maturationGO:00516041760.068
diterpenoid metabolic processGO:0016101240.068
Human
protein kinase b signalingGO:0043491740.066
Human
regulation of lipid biosynthetic processGO:0046890540.065
Human
response to peptideGO:19016521360.065
positive regulation of dopamine uptake involved in synaptic transmissionGO:005158620.064
response to molecule of bacterial originGO:00022371430.063
testosterone biosynthetic processGO:006137020.062
Human
neutral lipid metabolic processGO:0006638570.062
transmembrane transportGO:00550854120.061
positive regulation of cellular amine metabolic processGO:003324050.060
lymphocyte differentiationGO:00300982420.060
cellular response to steroid hormone stimulusGO:0071383330.059
Human
positive regulation of protein kinase b signalingGO:0051897320.059
Human
monocarboxylic acid biosynthetic processGO:0072330610.058
Human
regulation of membrane potentialGO:00423911920.057
catecholamine uptakeGO:009049340.057
inorganic anion transportGO:0015698430.057
negative regulation of protein metabolic processGO:00512482820.057
cellular response to antibioticGO:007123640.056
acylglycerol metabolic processGO:0006639550.055
cellular response to monosaccharide stimulusGO:0071326470.054
regulation of cell activationGO:00508652890.053
cation transportGO:00068123990.053
response to acid chemicalGO:00011011110.053
Human
cellular amine metabolic processGO:0044106440.051
regulation of transferase activityGO:00513382630.050
cellular response to peptide hormone stimulusGO:0071375920.049
negative regulation of cellular protein metabolic processGO:00322692470.049
response to insulinGO:00328681000.049
regulation of neurotransmitter levelsGO:0001505870.049
regulation of ion transportGO:00432692150.045
regulation of secretion by cellGO:19035302490.045
intracellular protein transportGO:00068862040.045
Human
cellular response to carbohydrate stimulusGO:0071322500.044
sensory perceptionGO:00076002450.044
inflammatory responseGO:00069542440.044
mitochondrion organizationGO:00070051340.043
organic acid biosynthetic processGO:0016053860.043
Human
cellular response to peptideGO:1901653920.043
regulation of metal ion transportGO:00109591060.042
response to oxidative stressGO:00069791230.042
Human
lipid localizationGO:00108761260.042
maintenance of locationGO:0051235890.041
regulation of cellular amine metabolic processGO:0033238200.041
isoprenoid metabolic processGO:0006720290.041
Human
triglyceride metabolic processGO:0006641510.040
cellular response to hexose stimulusGO:0071331470.040
response to corticosteroneGO:005141210.040
carbohydrate homeostasisGO:00335001280.040
positive regulation of defense responseGO:00313491240.040
negative regulation of molecular functionGO:00440922580.040
membrane organizationGO:00610242450.039
naphthalene metabolic processGO:001893110.039
protein processingGO:00164851630.038
calcitriol biosynthetic process from calciolGO:003637830.038
cellular response to cadmium ionGO:007127630.038
Human
regulation of lymphocyte mediated immunityGO:0002706840.037
leukocyte mediated immunityGO:00024431740.036
cellular response to insulin stimulusGO:0032869780.036
dopamine uptakeGO:009049440.036
response to mineralocorticoidGO:005138510.036
carbohydrate metabolic processGO:00059752300.035
urate transportGO:001574710.035
regulation of protein processingGO:0070613960.034
g protein coupled receptor signaling pathwayGO:00071862430.034
Human
cellular response to growth factor stimulusGO:00713631970.033
cellular response to organic cyclic compoundGO:0071407870.033
Human
response to follicle stimulating hormoneGO:003235410.033
negative regulation of cell proliferationGO:00082852960.033
sulfur compound metabolic processGO:00067901000.033
alpha amino acid metabolic processGO:1901605590.032
regulation of blood pressureGO:0008217930.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.032
cellular homeostasisGO:00197252400.032
response to monosaccharideGO:0034284670.032
immune effector processGO:00022523210.031
cellular glucose homeostasisGO:0001678520.031
regulation of catecholamine uptake involved in synaptic transmissionGO:005194020.031
response to growth factorGO:00708481980.031
response to fibroblast growth factorGO:0071774470.031
modified amino acid transportGO:007233750.031
regulation of cellular amino acid metabolic processGO:000652150.031
multi multicellular organism processGO:00447061090.031
regulation of carbohydrate biosynthetic processGO:0043255400.030
protein localization to organelleGO:00333651850.030
Human
peptide transportGO:00158331330.030
regulation of protein maturationGO:1903317960.030
chloride transmembrane transportGO:1902476240.030
vitamin d3 metabolic processGO:007064030.030
macromolecule catabolic processGO:00090572810.029
skeletal muscle organ developmentGO:00605381630.029
glutathione metabolic processGO:0006749160.028
acute inflammatory responseGO:0002526410.028
response to lipopolysaccharideGO:00324961280.028
endocytosisGO:00068971680.028
icosanoid metabolic processGO:0006690330.027
Human
muscle contractionGO:00069361010.027
positive regulation of catecholamine uptake involved in synaptic transmissionGO:005194420.027
response to xenobiotic stimulusGO:0009410130.027
regulation of inflammatory responseGO:00507271470.027
regulation of reactive oxygen species metabolic processGO:2000377400.027
Human
inorganic ion transmembrane transportGO:00986602340.027
mapk cascadeGO:00001652810.026
carbohydrate biosynthetic processGO:0016051740.026
maternal process involved in female pregnancyGO:0060135320.026
neurotransmitter transportGO:0006836760.026
alcohol biosynthetic processGO:0046165430.026
Human
regulation of complement activation classical pathwayGO:003045010.026
cation transmembrane transportGO:00986552660.025
organic hydroxy compound transportGO:0015850930.025
cellular response to ketoneGO:1901655120.025
response to nutrient levelsGO:00316671090.025
Human
organic cyclic compound catabolic processGO:19013612950.024
wound healingGO:00420601570.024
negative regulation of protein maturationGO:1903318790.024
cellular modified amino acid metabolic processGO:0006575630.024
regulation of protein kinase activityGO:00458592320.024
cellular response to organonitrogen compoundGO:00714171450.024
positive regulation of lipid transportGO:0032370220.023
vitamin d biosynthetic processGO:004236830.023
inorganic anion transmembrane transportGO:0098661290.023
cation homeostasisGO:00550802120.023
muscle tissue developmentGO:00605373080.023
sterol metabolic processGO:0016125580.023
fertilizationGO:00095661270.022
cellular macromolecule catabolic processGO:00442652060.022
l amino acid transportGO:0015807320.022
regulation of multi organism processGO:00439001110.022
proline transportGO:001582430.022
positive regulation of protein modification processGO:00314012990.022
gluconeogenesisGO:0006094390.022
hormone secretionGO:00468791280.021
multicellular organism growthGO:00352641610.021
response to testosteroneGO:003357430.021
porphyrin containing compound metabolic processGO:0006778220.021
peptidyl amino acid modificationGO:00181933360.021
lipid transportGO:0006869980.021
insulin receptor signaling pathwayGO:0008286490.021
regulation of dopamine uptake involved in synaptic transmissionGO:005158420.020
apoptotic signaling pathwayGO:00971903060.020
regulation of establishment of protein localizationGO:00702011810.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
cytoplasmic transportGO:00164822340.020
Human
tetrapyrrole metabolic processGO:0033013220.020
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.020
negative regulation of protein processingGO:0010955790.020
cellular response to gonadotropin stimulusGO:007137140.020
terpenoid metabolic processGO:0006721250.020
Human
regulation of cellular component biogenesisGO:00440871810.020
response to inorganic substanceGO:0010035960.020
Human
regulation of proteolysisGO:00301621640.020
inflammatory response to antigenic stimulusGO:0002437300.020
regulation of protein localizationGO:00328802310.019
cellular response to follicle stimulating hormone stimulusGO:007137210.019
negative regulation of immune system processGO:00026832090.019
folic acid containing compound metabolic processGO:000676030.019
lipid homeostasisGO:0055088630.019
regulation of endopeptidase activityGO:0052548890.019
neurotransmitter uptakeGO:0001504140.019
cellular response to alcoholGO:0097306230.019
regulation of protein catabolic processGO:00421761080.019
nucleotide metabolic processGO:00091173320.018
cellular response to foodGO:007124010.018
metal ion homeostasisGO:00550651890.018
renal tubular secretionGO:009725420.018
modification dependent protein catabolic processGO:00199411330.018
cellular response to acid chemicalGO:0071229680.018
Human
cellular chemical homeostasisGO:00550822150.018
regulation of cytoplasmic transportGO:19036491120.018
response to alcoholGO:0097305480.018
regulation of intracellular protein transportGO:0033157820.018
cellular alcohol biosynthetic processGO:004410830.018
phenol containing compound metabolic processGO:0018958600.017
cellular response to molecule of bacterial originGO:0071219830.017
positive regulation of apoptotic processGO:00430652170.017
Human
secondary alcohol metabolic processGO:190265230.017
monosaccharide biosynthetic processGO:0046364440.017
purine containing compound metabolic processGO:00725213110.017
regulation of mapk cascadeGO:00434082480.017
retinoic acid metabolic processGO:0042573120.017
Human
monoamine transportGO:0015844330.017
reactive oxygen species metabolic processGO:0072593840.017
Human
positive regulation of inflammatory responseGO:0050729470.017
regulation of leukocyte mediated immunityGO:00027031040.017
cellular response to lipopolysaccharideGO:0071222770.016
histamine uptakeGO:005161510.016
regulation of response to woundingGO:19030341890.016
regulation of acute inflammatory responseGO:0002673270.016
regulation of muscle tissue developmentGO:1901861970.016
regulation of anatomical structure sizeGO:00900661780.016
cellular response to oxidative stressGO:0034599760.016
Human
cellular aldehyde metabolic processGO:0006081120.016
Human
positive regulation of protein kinase activityGO:00458601440.016
glucose homeostasisGO:00425931280.016
renal system processGO:0003014480.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
cell activation involved in immune responseGO:00022631260.016
nucleocytoplasmic transportGO:00069131390.016
Human
ribose phosphate metabolic processGO:00196932910.015
cell substrate adhesionGO:00315891300.015
calcium ion homeostasisGO:00550741270.015
response to estrogenGO:0043627240.015
regulation of kinase activityGO:00435492490.015
regulation of peptide transportGO:0090087910.015
negative regulation of phosphorylationGO:00423261660.015
protein modification by small protein conjugation or removalGO:00706472070.015
pigment metabolic processGO:0042440320.015
regulation of body fluid levelsGO:00508781620.015
organic hydroxy compound biosynthetic processGO:1901617770.015
Human
negative regulation of protein modification processGO:00314001630.015
trachea cartilage morphogenesisGO:006053540.015
temperature homeostasisGO:0001659260.015
regulation of hydrolase activityGO:00513362460.015
cellular protein complex assemblyGO:00436231160.015
fibrinolysisGO:004273030.015
leukocyte differentiationGO:00025213420.015
organonitrogen compound catabolic processGO:19015652640.015
inter male aggressive behaviorGO:000212130.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
erk1 and erk2 cascadeGO:0070371770.014
purine containing compound catabolic processGO:00725232130.014
cellular response to glucose stimulusGO:0071333450.014
peptide secretionGO:00027901140.014
monosaccharide metabolic processGO:00059961060.014
response to drugGO:0042493750.014
regulation of protein kinase b signalingGO:0051896560.014
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
organonitrogen compound biosynthetic processGO:19015661920.014
regulation of organelle organizationGO:00330432890.014
negative regulation of protein phosphorylationGO:00019331260.014
cellular response to toxic substanceGO:009723770.014
response to steroid hormoneGO:0048545560.014
Human
catecholamine uptake involved in synaptic transmissionGO:005193440.014
fatty acid derivative metabolic processGO:1901568330.014
Human
regulation of cytokine productionGO:00018172660.013
regulation of endocytosisGO:0030100690.013
multicellular organismal signalingGO:0035637910.013
hexose biosynthetic processGO:0019319390.013
neuron neuron synaptic transmissionGO:0007270690.013
carnitine metabolic processGO:000943770.013
interspecies interaction between organismsGO:0044419830.013
cellular protein catabolic processGO:00442571550.013
symbiosis encompassing mutualism through parasitismGO:0044403830.013
cellular response to cytokine stimulusGO:00713451890.013
heme metabolic processGO:0042168160.013
regulation of anion transportGO:0044070270.013
homeostasis of number of cellsGO:00488722100.013
neuron deathGO:00709971540.013
positive regulation of lipid metabolic processGO:0045834400.013
fatty acid biosynthetic processGO:0006633410.013
cytokine mediated signaling pathwayGO:00192211150.013
synaptic transmissionGO:00072683290.013
positive regulation of cellular ph reductionGO:003284920.013
regulation of vesicle mediated transportGO:00606271390.013
innate immune responseGO:00450871570.013
response to dexamethasoneGO:007154880.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
mineralocorticoid biosynthetic processGO:000670510.013
regulation of apoptotic signaling pathwayGO:20012331970.013
c21 steroid hormone metabolic processGO:000820770.013
Human
organophosphate catabolic processGO:00464342320.013
protein catabolic processGO:00301632210.013
purine nucleotide catabolic processGO:00061952110.013
protein targetingGO:00066051430.012
Human
positive regulation of organelle organizationGO:00106381280.012
response to extracellular stimulusGO:00099911270.012
Human
negative regulation of phosphorus metabolic processGO:00105631840.012
myeloid cell differentiationGO:00300992330.012
purine nucleotide metabolic processGO:00061633020.012
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.012
reactive oxygen species biosynthetic processGO:190340980.012
response to hydrogen peroxideGO:0042542320.012
lipid storageGO:0019915360.012
positive regulation of response to woundingGO:1903036660.012
development of primary female sexual characteristicsGO:0046545730.012
regulation of cellular catabolic processGO:00313292420.012
naphthalene containing compound metabolic processGO:009042010.012
locomotory behaviorGO:00076261950.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
dopamine uptake involved in synaptic transmissionGO:005158340.012
chemokine metabolic processGO:0050755100.012
muscle cell differentiationGO:00426922610.012
cellular calcium ion homeostasisGO:00068741190.012
regulation of striated muscle cell differentiationGO:0051153810.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
nucleoside catabolic processGO:00091642060.012
positive regulation of cell developmentGO:00107202370.012
sensory perception of mechanical stimulusGO:00509541070.012
regulation of complement activationGO:003044970.012
striated muscle tissue developmentGO:00147062930.012
protein polymerizationGO:0051258570.012
positive regulation of secretionGO:00510471300.012
regulation of gluconeogenesisGO:0006111300.011
regulation of lipid metabolic processGO:00192161180.011
Human
regulation of feeding behaviorGO:006025930.011
keratinocyte migrationGO:005154630.011
nucleoside metabolic processGO:00091162460.011
regulation of protein serine threonine kinase activityGO:00719001570.011
bile acid metabolic processGO:0008206170.011
Human
regulation of transmembrane transportGO:00347621280.011
response to metal ionGO:0010038470.011
Human
dopamine transportGO:0015872150.011
secondary metabolic processGO:0019748180.011
Human
leydig cell differentiationGO:0033327100.011
negative regulation of proteolysisGO:0045861740.011
generation of precursor metabolites and energyGO:00060911030.011
organophosphate biosynthetic processGO:00904071220.011
positive regulation of secretion by cellGO:19035321140.011
fatty acid transportGO:0015908280.011
negative regulation of sterol transportGO:003237240.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
midgut developmentGO:000749440.011
leukocyte proliferationGO:00706611720.011
calcium ion transportGO:00068161590.011
peptide hormone secretionGO:00300721090.011
negative regulation of cholesterol effluxGO:009037040.011
fat soluble vitamin metabolic processGO:0006775110.011
endocrine processGO:0050886390.011
protein localization to nucleusGO:00345041210.011
Human
development of primary male sexual characteristicsGO:0046546880.011
Human
endomembrane system organizationGO:00102561470.011
regulation of map kinase activityGO:00434051200.011
adaptive immune responseGO:00022501550.010
negative regulation of phosphate metabolic processGO:00459361840.010
hematopoietic progenitor cell differentiationGO:00022441430.010
hexose metabolic processGO:0019318980.010
fat soluble vitamin catabolic processGO:004236310.010
cellular carbohydrate metabolic processGO:00442621190.010
transmission of nerve impulseGO:0019226760.010
female gamete generationGO:0007292740.010
regulation of system processGO:00440572000.010
positive regulation of vasoconstrictionGO:004590740.010
positive regulation of proteolysisGO:0045862850.010
positive regulation of ion transportGO:0043270650.010
ribonucleoside metabolic processGO:00091192450.010
cellular nitrogen compound catabolic processGO:00442702800.010
regulation of intracellular transportGO:00323861590.010
cognitionGO:00508901490.010
drug metabolic processGO:001714440.010
prevention of polyspermyGO:006046840.010
response to bile acidGO:190341210.010

Akr1c21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
steroid inherited metabolic disorderDOID:170100.305
inherited metabolic disorderDOID:65500.305
disease of metabolismDOID:001466700.305
lipid metabolism disorderDOID:314600.305
immune system diseaseDOID:291400.031
disease of anatomical entityDOID:700.031
congenital adrenal hyperplasiaDOID:005081100.031
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.021
hematopoietic system diseaseDOID:7400.019
urinary system diseaseDOID:1800.013