Mus musculus

29 known processes

Rheb

Ras homolog enriched in brain

Rheb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine ribonucleotide metabolic processGO:00091502900.333
Fly
pigment granule localizationGO:0051875130.327
establishment of melanosome localizationGO:0032401110.294
melanosome localizationGO:0032400120.245
organonitrogen compound catabolic processGO:19015652640.180
Fly
dna metabolic processGO:00062593030.174
glycosyl compound catabolic processGO:19016582060.159
Fly
glycosyl compound metabolic processGO:19016572460.155
Fly
nucleoside triphosphate metabolic processGO:00091412300.153
Fly
gtp metabolic processGO:00460391440.150
Fly
regulation of ion transportGO:00432692150.150
purine nucleoside catabolic processGO:00061522050.136
Fly
purine containing compound catabolic processGO:00725232130.134
Fly
regulation of cell motilityGO:20001452360.132
nucleoside metabolic processGO:00091162460.131
Fly
nucleotide metabolic processGO:00091173320.131
Fly
ribonucleoside metabolic processGO:00091192450.130
Fly
gtp catabolic processGO:00061841430.129
Fly
purine nucleotide metabolic processGO:00061633020.128
Fly
protein catabolic processGO:00301632210.123
regulation of cellular component biogenesisGO:00440871810.119
Fly
protein modification by small protein conjugationGO:00324461870.117
establishment of organelle localizationGO:00516561220.114
ribonucleoside catabolic processGO:00424542060.111
Fly
ribonucleotide catabolic processGO:00092612080.109
Fly
organic cyclic compound catabolic processGO:19013612950.107
Fly
organophosphate catabolic processGO:00464342320.107
Fly
positive regulation of apoptotic processGO:00430652170.101
purine ribonucleoside metabolic processGO:00461282410.100
Fly
regulation of neuron differentiationGO:00456642810.099
nucleoside phosphate metabolic processGO:00067533380.094
Fly
regulation of cellular catabolic processGO:00313292420.093
Fly
guanosine containing compound catabolic processGO:19010691440.092
Fly
positive regulation of cell deathGO:00109422240.091
purine containing compound metabolic processGO:00725213110.091
Fly
carbohydrate derivative catabolic processGO:19011362310.089
Fly
nucleoside phosphate catabolic processGO:19012922220.088
Fly
endomembrane system organizationGO:00102561470.088
purine ribonucleoside catabolic processGO:00461302050.088
Fly
regulation of cell migrationGO:00303342190.088
purine ribonucleoside triphosphate catabolic processGO:00092071990.085
Fly
purine nucleoside triphosphate catabolic processGO:00091462030.084
Fly
purine nucleoside metabolic processGO:00422782410.083
Fly
cation transportGO:00068123990.080
purine nucleoside triphosphate metabolic processGO:00091442260.079
Fly
organelle localizationGO:00516401790.075
positive regulation of programmed cell deathGO:00430682180.073
ion transmembrane transportGO:00342203610.071
membrane organizationGO:00610242450.070
aromatic compound catabolic processGO:00194392860.070
Fly
heterocycle catabolic processGO:00467002800.070
Fly
ribonucleotide metabolic processGO:00092592910.069
Fly
cellular nitrogen compound catabolic processGO:00442702800.068
Fly
cellular protein catabolic processGO:00442571550.067
purine ribonucleotide catabolic processGO:00091542080.067
Fly
synaptic transmissionGO:00072683290.065
guanosine containing compound metabolic processGO:19010681440.065
Fly
amine metabolic processGO:0009308450.065
cellular ketone metabolic processGO:0042180840.064
purine ribonucleoside triphosphate metabolic processGO:00092052200.063
Fly
macromolecule catabolic processGO:00090572810.062
negative regulation of protein metabolic processGO:00512482820.062
regulation of cellular amino acid metabolic processGO:000652150.061
vacuole organizationGO:0007033380.061
ribose phosphate metabolic processGO:00196932910.061
Fly
cation transmembrane transportGO:00986552660.059
ribonucleoside triphosphate metabolic processGO:00091992200.059
Fly
ubiquitin dependent protein catabolic processGO:00065111290.059
nucleoside triphosphate catabolic processGO:00091432050.057
Fly
organelle assemblyGO:00709251770.057
protein modification by small protein conjugation or removalGO:00706472070.057
peptidyl amino acid modificationGO:00181933360.056
transmembrane transportGO:00550854120.056
defense response to other organismGO:00985421970.055
nucleoside catabolic processGO:00091642060.055
Fly
nucleobase containing small molecule metabolic processGO:00550863520.055
Fly
regulation of cellular ketone metabolic processGO:0010565660.054
vesicle localizationGO:0051648860.054
nucleotide catabolic processGO:00091662170.054
Fly
cellular amine metabolic processGO:0044106440.052
regulation of organelle organizationGO:00330432890.052
apoptotic signaling pathwayGO:00971903060.051
cytoplasmic transportGO:00164822340.051
cellular macromolecule catabolic processGO:00442652060.050
localization within membraneGO:005166840.050
nitrogen compound transportGO:00717052710.049
striated muscle tissue developmentGO:00147062930.048
regulation of intracellular transportGO:00323861590.048
intracellular protein transportGO:00068862040.048
divalent metal ion transportGO:00708381720.047
protein targetingGO:00066051430.047
regulation of cellular amine metabolic processGO:0033238200.047
positive regulation of apoptotic signaling pathwayGO:2001235950.046
regulation of kinase activityGO:00435492490.046
regulation of transmembrane transportGO:00347621280.045
regulation of neuron projection developmentGO:00109751690.044
regulation of cell projection organizationGO:00313442060.044
organic acid transportGO:00158491010.044
regulation of cytoplasmic transportGO:19036491120.044
copii coated vesicle buddingGO:009011420.044
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.043
cell adhesionGO:00071553290.043
interleukin 8 secretionGO:007260630.042
regulation of anatomical structure sizeGO:00900661780.042
Fly
establishment of pigment granule localizationGO:0051905120.042
ribonucleoside triphosphate catabolic processGO:00092031990.042
Fly
positive regulation of cell projection organizationGO:0031346950.041
divalent inorganic cation transportGO:00725111780.041
cellular response to organonitrogen compoundGO:00714171450.041
regulation of establishment of protein localizationGO:00702011810.039
regulation of protein localizationGO:00328802310.039
purine nucleotide catabolic processGO:00061952110.038
Fly
proteasomal protein catabolic processGO:0010498980.038
inorganic cation transmembrane transportGO:00986622070.038
negative regulation of synaptic vesicle transportGO:190280430.037
modification dependent macromolecule catabolic processGO:00436321330.037
positive regulation of protein modification processGO:00314012990.037
cellular amino acid metabolic processGO:00065201030.036
regulation of secretionGO:00510462740.036
establishment of vesicle localizationGO:0051650810.035
dendrite developmentGO:00163581150.035
negative regulation of cell proliferationGO:00082852960.034
regionalizationGO:00030023370.034
melanosome transportGO:0032402110.034
regulation of proteolysisGO:00301621640.033
t cell activationGO:00421102890.033
cellular homeostasisGO:00197252400.032
interleukin 8 productionGO:003263740.032
cellular chemical homeostasisGO:00550822150.032
regulation of apoptotic signaling pathwayGO:20012331970.032
neurotransmitter transportGO:0006836760.031
positive regulation of hydrolase activityGO:00513451480.031
response to organonitrogen compoundGO:00102432460.031
regulation of protein catabolic processGO:00421761080.031
regulation of cellular response to stressGO:00801351590.031
nuclear divisionGO:00002801580.030
regulation of secretion by cellGO:19035302490.030
negative regulation of phosphorus metabolic processGO:00105631840.030
protein localization to organelleGO:00333651850.030
lipid transportGO:0006869980.030
meiotic cell cycleGO:00513211220.029
negative regulation of cellular protein metabolic processGO:00322692470.029
regulation of neurotransmitter secretionGO:0046928290.029
muscle tissue developmentGO:00605373080.029
immune effector processGO:00022523210.029
response to starvationGO:0042594650.029
Fly
regulation of protein serine threonine kinase activityGO:00719001570.028
protein refoldingGO:004202610.028
carbohydrate homeostasisGO:00335001280.028
regulation of transferase activityGO:00513382630.027
nuclear transportGO:00511691390.027
histone modificationGO:00165701590.027
intra golgi vesicle mediated transportGO:000689110.027
negative regulation of intracellular protein transportGO:0090317270.027
regulation of membrane potentialGO:00423911920.027
positive regulation of cell developmentGO:00107202370.027
retrograde transport endosome to golgiGO:004214720.026
regulation of protein kinase activityGO:00458592320.026
pigment granule transportGO:0051904120.026
positive regulation of nervous system developmentGO:00519622210.025
actin cytoskeleton organizationGO:00300362200.025
connective tissue developmentGO:00614481790.025
regulation of cell cycleGO:00517262810.025
regulation of nucleotide catabolic processGO:00308111220.025
inorganic ion transmembrane transportGO:00986602340.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of ion transmembrane transportGO:00347651190.025
chromatin organizationGO:00063252060.025
regulation of cell divisionGO:0051302760.025
regulation of vesicle mediated transportGO:00606271390.024
cellularizationGO:000734910.024
positive regulation of proteolysisGO:0045862850.024
skeletal system developmentGO:00015013560.024
macromolecular complex disassemblyGO:0032984430.024
anion transportGO:00068201770.024
dephosphorylationGO:00163111290.024
regulation of vacuole organizationGO:004408840.024
dna templated transcriptional preinitiation complex assemblyGO:007089740.024
small gtpase mediated signal transductionGO:0007264970.024
response to nutrient levelsGO:00316671090.024
Fly
metal ion homeostasisGO:00550651890.024
peptidyl tyrosine phosphorylationGO:00181081430.023
calcium ion transportGO:00068161590.023
protein processingGO:00164851630.023
positive regulation of protein phosphorylationGO:00019342420.023
cellular lipid metabolic processGO:00442553230.023
protein ubiquitinationGO:00165671710.023
regulation of calcium ion transportGO:0051924690.022
regulation of purine nucleotide catabolic processGO:00331211220.022
modification dependent protein catabolic processGO:00199411330.022
lymphocyte mediated immunityGO:00024491390.022
positive regulation of cellular amine metabolic processGO:003324050.022
blood vessel morphogenesisGO:00485142850.022
glycoprotein metabolic processGO:00091001160.022
positive regulation of neuron differentiationGO:00456661410.022
cellular protein complex assemblyGO:00436231160.022
protein neddylationGO:004511610.022
cell growthGO:00160491300.022
Fly
protein methylationGO:0006479810.021
cellular ion homeostasisGO:00068731650.021
muscle cell differentiationGO:00426922610.021
chromosome segregationGO:0007059480.021
response to light stimulusGO:00094161350.021
Fly
regulation of system processGO:00440572000.021
fertilizationGO:00095661270.021
autophagyGO:0006914450.021
Fly
cytokine productionGO:00018163190.021
cargo loading into vesicleGO:003545930.020
single organism cell adhesionGO:00986021560.020
mitotic cytokinesisGO:000028140.020
regulation of autophagic vacuole assemblyGO:200078540.020
stem cell differentiationGO:00488632680.020
positive regulation of dna templated transcription elongationGO:003278620.020
organic anion transportGO:00157111370.020
calcium ion transmembrane transportGO:0070588850.020
regulation of hormone levelsGO:00108172110.020
regulation of peptidase activityGO:0052547960.020
regulation of metal ion transportGO:00109591060.020
chromatin modificationGO:00165681870.020
cell recognitionGO:0008037830.020
response to inorganic substanceGO:0010035960.020
wnt signaling pathwayGO:00160551880.020
cation homeostasisGO:00550802120.020
multicellular organismal homeostasisGO:00488711640.020
nucleocytoplasmic transportGO:00069131390.019
establishment of synaptic vesicle localizationGO:0097480570.019
regulation of mapk cascadeGO:00434082480.019
establishment of protein localization to organelleGO:00725941180.019
gene silencingGO:0016458380.019
negative regulation of phosphate metabolic processGO:00459361840.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
organelle fissionGO:00482851700.019
peptidyl tyrosine modificationGO:00182121450.019
regulation of transporter activityGO:0032409570.019
heart processGO:0003015940.019
response to organic cyclic compoundGO:00140701980.019
protein localization to plasma membraneGO:0072659570.018
regulation of hydrolase activityGO:00513362460.018
regulation of protein transportGO:00512231630.018
nucleus localizationGO:0051647200.018
calcium ion homeostasisGO:00550741270.018
meiotic cell cycle processGO:1903046770.018
cellular response to extracellular stimulusGO:0031668810.018
divalent inorganic cation homeostasisGO:00725071380.018
lipid localizationGO:00108761260.018
golgi vesicle transportGO:0048193300.018
protein import into nucleusGO:0006606950.018
regulation of cell activationGO:00508652890.018
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.018
negative regulation of synaptic vesicle exocytosisGO:200030130.018
vesicle organizationGO:0016050600.018
cellular metal ion homeostasisGO:00068751510.018
regulation of cell shapeGO:0008360390.018
defense response to bacteriumGO:00427421190.018
negative regulation of molecular functionGO:00440922580.017
regulation of autophagyGO:0010506300.017
Fly
positive regulation of cellular catabolic processGO:00313311480.017
protein importGO:00170381010.017
response to radiationGO:00093141650.017
Fly
protein localization to nucleusGO:00345041210.017
positive regulation of secretion by cellGO:19035321140.017
striated muscle cell developmentGO:00550021250.017
regulation of neurotransmitter levelsGO:0001505870.017
single fertilizationGO:0007338820.017
cell divisionGO:00513011200.017
protein acylationGO:0043543640.017
protein maturationGO:00516041760.017
maintenance of locationGO:0051235890.017
oxidation reduction processGO:00551143420.017
covalent chromatin modificationGO:00165691630.017
positive regulation of secretionGO:00510471300.017
ras protein signal transductionGO:0007265770.016
sensory perceptionGO:00076002450.016
negative regulation of protein transportGO:0051224460.016
carbohydrate metabolic processGO:00059752300.016
Fly
cellular response to dna damage stimulusGO:00069742070.016
positive regulation of smooth muscle cell migrationGO:001491140.016
regulation of lymphocyte activationGO:00512492400.016
circulatory system processGO:00030131970.016
establishment of protein localization to vacuoleGO:007266640.016
forebrain developmentGO:00309003020.016
protein localization to membraneGO:00726571080.016
negative regulation of protein modification processGO:00314001630.016
toxin transportGO:1901998380.016
endocytosisGO:00068971680.016
regulation of protein maturationGO:1903317960.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
response to extracellular stimulusGO:00099911270.016
Fly
stem cell developmentGO:00488642190.015
cellular pigmentationGO:0033059200.015
vesicle transport along microtubuleGO:004749690.015
regulation of cellular component sizeGO:00325351210.015
Fly
peptide secretionGO:00027901140.015
anatomical structure homeostasisGO:00602491450.015
cellular calcium ion homeostasisGO:00068741190.015
exocytosisGO:00068871210.015
negative regulation of cytoplasmic transportGO:1903650290.015
lipid biosynthetic processGO:00086101790.015
epithelial tube morphogenesisGO:00605623030.015
regulation of mitotic cell cycleGO:00073461260.015
cell substrate adhesionGO:00315891300.015
microtubule based processGO:00070172360.015
glycerophospholipid metabolic processGO:0006650710.015
actin filament organizationGO:00070151130.015
atp metabolic processGO:0046034750.015
microtubule cytoskeleton organizationGO:00002261570.015
small molecule biosynthetic processGO:00442831320.015
regulation of protein processingGO:0070613960.015
gonad developmentGO:00084061410.015
regulation of cell cycle processGO:00105641600.015
negative regulation of cellular component organizationGO:00511291940.014
regulation of cell growthGO:0001558910.014
glycerolipid metabolic processGO:00464861220.014
phospholipid metabolic processGO:0006644870.014
establishment of protein localization to membraneGO:0090150540.014
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.014
centrosome separationGO:005129940.014
microtubule based movementGO:0007018840.014
synapse organizationGO:00508081250.014
Fly
negative regulation of protein maturationGO:1903318790.014
lymphocyte proliferationGO:00466511640.014
dna recombinationGO:0006310920.014
positive regulation of insulin secretionGO:0032024260.014
nucleobase containing compound transportGO:0015931270.014
peptidyl lysine modificationGO:0018205770.014
carboxylic acid transportGO:00469421000.014
germ cell developmentGO:00072811850.014
epithelial cell developmentGO:00020641590.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
sequestering of calcium ionGO:0051208180.014
regulation of neurotransmitter transportGO:0051588350.014
protein secretionGO:00093061110.014
mitotic cell cycle processGO:19030471590.014
Fly
regulation of protein targetingGO:1903533610.014
skeletal muscle cell differentiationGO:0035914660.014
regulation of actin filament based processGO:0032970990.014
carbohydrate derivative biosynthetic processGO:19011371830.014
cytokinesisGO:0000910170.014
b cell activationGO:00421131610.014
development of primary sexual characteristicsGO:00451371430.014
positive regulation of transferase activityGO:00513471670.013
positive regulation of nucleotide metabolic processGO:00459811140.013
mapk cascadeGO:00001652810.013
male gamete generationGO:00482322850.013
regulation of intracellular protein transportGO:0033157820.013
nuclear importGO:0051170950.013
immune response in mucosal associated lymphoid tissueGO:000238620.013
telencephalon developmentGO:00215371860.013
cytosolic calcium ion homeostasisGO:0051480700.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
axonogenesisGO:00074092740.013
Fly
lymphocyte differentiationGO:00300982420.013
golgi to endosome transportGO:000689530.013
respiratory system developmentGO:00605411900.013
regulation of cell adhesionGO:00301551540.013
positive regulation of mapk cascadeGO:00434101700.013
negative regulation of cell developmentGO:00107211690.013
learning or memoryGO:00076111480.013
leukocyte proliferationGO:00706611720.013
gland developmentGO:00487323300.013
hormone secretionGO:00468791280.013
macromolecule methylationGO:00434141200.013
rap protein signal transductionGO:003248630.013
morphogenesis of embryonic epitheliumGO:00163311590.013
regulation of cell sizeGO:0008361720.012
Fly
regulation of ras gtpase activityGO:0032318880.012
ribonucleoprotein complex disassemblyGO:003298830.012
response to metal ionGO:0010038470.012
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
cellular response to cytokine stimulusGO:00713451890.012
regulation of vasculature developmentGO:1901342880.012
carboxylic acid biosynthetic processGO:0046394860.012
response to molecule of bacterial originGO:00022371430.012
single organism nuclear importGO:1902593950.012
regulation of homeostatic processGO:00328441820.012
neurotransmitter secretionGO:0007269620.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
pigmentationGO:0043473710.012
regulation of t cell activationGO:00508631700.012
regulation of peptide transportGO:0090087910.012
cellular response to hormone stimulusGO:00328701500.012
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.012
rho protein signal transductionGO:0007266320.012
ossificationGO:00015032160.012
cellular response to starvationGO:0009267570.012
translationGO:0006412930.012
Fly
meiotic nuclear divisionGO:00071261150.012
glucose homeostasisGO:00425931280.012
protein complex disassemblyGO:0043241400.012
negative regulation of cell motilityGO:2000146610.012
epithelial cell proliferationGO:00506731740.012
regulation of hormone secretionGO:0046883880.012
amide transportGO:00428861380.012
plasma membrane organizationGO:0007009900.012
wound healingGO:00420601570.011
posttranscriptional regulation of gene expressionGO:00106081550.011
Fly
positive regulation of cell activationGO:00508671580.011
organic acid biosynthetic processGO:0016053860.011
rna interferenceGO:001624620.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
inflammatory responseGO:00069542440.011
regulation of adaptive immune responseGO:0002819900.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
positive regulation of phospholipase activityGO:001051830.011
heart contractionGO:0060047930.011
regulation of bindingGO:00510981110.011
protein localization to vacuoleGO:007266540.011
cartilage developmentGO:00512161400.011
virion assemblyGO:001906810.011
adult behaviorGO:00305341350.011
positive regulation of neuron projection developmentGO:0010976790.011
mitochondrial transportGO:0006839360.011
positive regulation of cell motilityGO:20001471160.011
metaphase plate congressionGO:005131020.011
negative regulation of nervous system developmentGO:00519611560.011
epidermis developmentGO:00085441870.011
sequestering of metal ionGO:0051238190.011
positive regulation of protein kinase activityGO:00458601440.011
angiogenesisGO:00015252010.011
carbohydrate biosynthetic processGO:0016051740.011
regulation of transcription factor import into nucleusGO:0042990240.011
regulation of defense responseGO:00313472330.011
negative regulation of protein phosphorylationGO:00019331260.011
regulation of embryonic developmentGO:0045995710.011
mitotic cell cycleGO:00002781950.011
Fly
negative regulation of kinase activityGO:0033673810.011
negative regulation of protein localization to nucleusGO:1900181230.011
positive regulation of protein autophosphorylationGO:003195440.011
mitochondrion organizationGO:00070051340.011
regulation of cellular protein catabolic processGO:1903362610.011
muscle contractionGO:00069361010.011
leukocyte mediated immunityGO:00024431740.011
substantia nigra developmentGO:002176220.011
negative regulation of intracellular signal transductionGO:19025321670.011
regulation of heart contractionGO:0008016770.011
hematopoietic progenitor cell differentiationGO:00022441430.011
negative regulation of intracellular transportGO:0032387380.011
oocyte constructionGO:000730820.010
myosin filament organizationGO:003103330.010
regulation of peptidyl tyrosine phosphorylationGO:0050730930.010
canonical wnt signaling pathwayGO:00600701300.010
monocarboxylic acid metabolic processGO:00327871910.010
positive regulation of kinase activityGO:00336741550.010
endoplasmic reticulum organizationGO:0007029100.010
actomyosin structure organizationGO:0031032560.010
negative regulation of protein processingGO:0010955790.010
positive regulation of ion transportGO:0043270650.010
signal transduction in absence of ligandGO:0038034550.010
striated muscle myosin thick filament assemblyGO:007168810.010
membrane fusionGO:0061025380.010
organic hydroxy compound metabolic processGO:19016152030.010
response to peptideGO:19016521360.010
innate immune responseGO:00450871570.010
branching morphogenesis of an epithelial tubeGO:00487541590.010
cellular carbohydrate metabolic processGO:00442621190.010
locomotory behaviorGO:00076261950.010
regulation of lipid metabolic processGO:00192161180.010

Rheb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
eye diseaseDOID:561400.017
sensory system diseaseDOID:005015500.017
retinal diseaseDOID:567900.017
eye and adnexa diseaseDOID:149200.017
retinal degenerationDOID:846600.017
immune system diseaseDOID:291400.013