Mus musculus

0 known processes

Hic2

hypermethylated in cancer 2

(Aliases: AA409108,HRG22,mKIAA1020)

Hic2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
male gamete generationGO:00482322850.114
regionalizationGO:00030023370.104
muscle tissue developmentGO:00605373080.102
telencephalon developmentGO:00215371860.083
cell adhesionGO:00071553290.081
leukocyte differentiationGO:00025213420.080
regulation of neuron differentiationGO:00456642810.079
skeletal system developmentGO:00015013560.066
hematopoietic progenitor cell differentiationGO:00022441430.065
spermatogenesisGO:00072832840.065
central nervous system neuron differentiationGO:00219531620.062
striated muscle tissue developmentGO:00147062930.060
forebrain developmentGO:00309003020.056
regulation of cellular amino acid metabolic processGO:000652150.054
positive regulation of nervous system developmentGO:00519622210.053
histone modificationGO:00165701590.053
muscle cell differentiationGO:00426922610.053
pallium developmentGO:00215431200.052
embryonic organ morphogenesisGO:00485622760.052
chromatin organizationGO:00063252060.052
morphogenesis of embryonic epitheliumGO:00163311590.051
negative regulation of cellular amino acid metabolic processGO:004576300.051
gland developmentGO:00487323300.050
positive regulation of neuron differentiationGO:00456661410.049
chromatin modificationGO:00165681870.048
morphogenesis of a branching structureGO:00017632030.048
regulation of cellular amine metabolic processGO:0033238200.048
placenta developmentGO:00018901400.048
neural tube developmentGO:00219151600.047
neural tube closureGO:0001843900.046
amine metabolic processGO:0009308450.046
primary neural tube formationGO:0014020950.045
skeletal system morphogenesisGO:00487052030.044
regulation of organ morphogenesisGO:20000271440.044
dendrite developmentGO:00163581150.043
axonogenesisGO:00074092740.042
cellular amino acid metabolic processGO:00065201030.042
negative regulation of molecular functionGO:00440922580.041
renal system developmentGO:00720012250.041
blood vessel morphogenesisGO:00485142850.041
neural precursor cell proliferationGO:00613511210.041
ameboidal type cell migrationGO:00016671280.041
stem cell differentiationGO:00488632680.041
blastocyst developmentGO:0001824800.040
tube formationGO:00351481400.040
negative regulation of cellular protein metabolic processGO:00322692470.040
epithelial tube formationGO:00721751300.040
cell fate commitmentGO:00451652100.040
tube closureGO:0060606910.038
connective tissue developmentGO:00614481790.038
stem cell proliferationGO:00720891170.037
oxidation reduction processGO:00551143420.037
response to organonitrogen compoundGO:00102432460.036
stem cell maintenanceGO:00198271300.036
developmental growth involved in morphogenesisGO:00605601380.036
cellular ketone metabolic processGO:0042180840.036
response to acid chemicalGO:00011011110.035
camera type eye developmentGO:00430102660.035
ras protein signal transductionGO:0007265770.034
carbohydrate metabolic processGO:00059752300.034
embryonic epithelial tube formationGO:00018381300.034
digestive tract developmentGO:00485651900.033
positive regulation of cell developmentGO:00107202370.033
neural tube formationGO:00018411080.032
mapk cascadeGO:00001652810.032
myeloid leukocyte differentiationGO:00025731190.032
lymphocyte differentiationGO:00300982420.032
cerebral cortex developmentGO:0021987860.032
dna metabolic processGO:00062593030.032
negative regulation of nervous system developmentGO:00519611560.032
protein ubiquitinationGO:00165671710.032
cell maturationGO:00484691270.031
regulation of organelle organizationGO:00330432890.031
regulation of mapk cascadeGO:00434082480.031
inner ear morphogenesisGO:00424721010.031
regulation of cell morphogenesis involved in differentiationGO:00107691510.030
regulation of cellular ketone metabolic processGO:0010565660.030
cellular macromolecule catabolic processGO:00442652060.030
myeloid cell differentiationGO:00300992330.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
covalent chromatin modificationGO:00165691630.029
skin developmentGO:00435882200.029
sensory organ morphogenesisGO:00905962420.029
macromolecule methylationGO:00434141200.028
neuron deathGO:00709971540.028
cellular response to acid chemicalGO:0071229680.028
retina development in camera type eyeGO:00600411190.027
digestive system developmentGO:00551232000.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
neural crest cell migrationGO:0001755320.027
posttranscriptional regulation of gene expressionGO:00106081550.027
positive regulation of cellular amine metabolic processGO:003324050.027
peptidyl amino acid modificationGO:00181933360.027
positive regulation of protein modification processGO:00314012990.027
diencephalon developmentGO:0021536630.027
urogenital system developmentGO:00016552610.026
visceral motor neuron differentiationGO:002152430.026
protein modification by small protein conjugation or removalGO:00706472070.026
lateral inhibitionGO:004633110.026
negative regulation of cellular amine metabolic processGO:003323910.026
hexose metabolic processGO:0019318980.026
small gtpase mediated signal transductionGO:0007264970.026
angiogenesisGO:00015252010.026
nitrogen compound transportGO:00717052710.026
neuron apoptotic processGO:00514021420.026
glial cell differentiationGO:00100011310.026
neuron projection guidanceGO:00974851410.025
regulation of cell adhesionGO:00301551540.025
epithelial tube morphogenesisGO:00605623030.025
protein modification by small protein conjugationGO:00324461870.024
regulation of cellular catabolic processGO:00313292420.024
regulation of body fluid levelsGO:00508781620.024
embryonic placenta developmentGO:0001892980.024
cell type specific apoptotic processGO:00972852680.024
asymmetric stem cell divisionGO:009872230.024
ectoderm formationGO:000170530.024
glycerolipid metabolic processGO:00464861220.024
organonitrogen compound biosynthetic processGO:19015661920.023
methylationGO:00322591340.023
positive regulation of apoptotic processGO:00430652170.023
carbohydrate homeostasisGO:00335001280.022
cellular carbohydrate metabolic processGO:00442621190.022
stem cell developmentGO:00488642190.022
peptide transportGO:00158331330.022
cardiac muscle tissue developmentGO:00487381300.022
neuron migrationGO:00017641220.022
regulation of neuron apoptotic processGO:00435231220.022
negative regulation of cell differentiation involved in embryonic placenta developmentGO:006080610.022
dna methylation involved in gamete generationGO:0043046150.022
purine containing compound metabolic processGO:00725213110.022
glucose homeostasisGO:00425931280.022
nucleobase containing small molecule metabolic processGO:00550863520.022
gliogenesisGO:00420631410.021
cerebral cortex radially oriented cell migrationGO:0021799310.021
cellular response to lipidGO:00713961450.021
nucleotide metabolic processGO:00091173320.021
compound eye developmentGO:004874910.021
morphogenesis of a branching epitheliumGO:00611381930.021
positive regulation of programmed cell deathGO:00430682180.021
cardiocyte differentiationGO:0035051870.021
heart morphogenesisGO:00030071780.021
macromolecule catabolic processGO:00090572810.021
regulation of protein kinase activityGO:00458592320.021
inflammatory responseGO:00069542440.021
developmental cell growthGO:0048588840.021
negative regulation of cellular component organizationGO:00511291940.020
negative regulation of phosphate metabolic processGO:00459361840.020
regulation of vasculature developmentGO:1901342880.020
negative regulation of intracellular signal transductionGO:19025321670.020
signal transduction by p53 class mediatorGO:0072331510.020
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
blastocyst formationGO:0001825330.020
synapse organizationGO:00508081250.020
regulation of chromosome organizationGO:0033044830.020
negative regulation of cell developmentGO:00107211690.020
notch signaling pathwayGO:0007219710.020
reactive oxygen species metabolic processGO:0072593840.020
negative regulation of phosphorylationGO:00423261660.020
cellular response to organonitrogen compoundGO:00714171450.020
cation transmembrane transportGO:00986552660.020
dephosphorylationGO:00163111290.020
negative regulation of phosphorus metabolic processGO:00105631840.020
cell proliferation in hindbrainGO:0021534100.020
mitochondrion distributionGO:004831140.020
alpha beta t cell differentiationGO:0046632690.020
regulation of nucleotide metabolic processGO:00061401690.019
negative regulation of neuron differentiationGO:00456651010.019
regulation of intracellular protein transportGO:0033157820.019
regulation of neuron projection developmentGO:00109751690.019
hindbrain developmentGO:00309021280.019
negative regulation of immune system processGO:00026832090.019
protein methylationGO:0006479810.019
apoptotic signaling pathwayGO:00971903060.019
Mouse
regulation of cell projection organizationGO:00313442060.019
regulation of ossificationGO:00302781120.019
ribonucleotide metabolic processGO:00092592910.019
regulation of leukocyte differentiationGO:19021051590.019
cell growthGO:00160491300.019
sensory system developmentGO:004888030.019
regulation of neuron deathGO:19012141340.019
mesoderm developmentGO:00074981000.019
transmission of nerve impulseGO:0019226760.019
nerve developmentGO:0021675670.019
monosaccharide metabolic processGO:00059961060.019
regulation of intracellular transportGO:00323861590.019
regulation of peptide transportGO:0090087910.019
histone lysine methylationGO:0034968500.019
regulation of secretion by cellGO:19035302490.018
kidney developmentGO:00018222130.018
histone methylationGO:0016571710.018
b cell activationGO:00421131610.018
alpha beta t cell activationGO:0046631910.018
organelle fissionGO:00482851700.018
germ cell developmentGO:00072811850.018
regulation of hormone levelsGO:00108172110.018
regulation of tongue muscle cell differentiationGO:200103520.018
protein targetingGO:00066051430.018
neural crest cell differentiationGO:0014033540.018
gastrulationGO:00073691160.018
regulation of apoptotic signaling pathwayGO:20012331970.018
pharynx developmentGO:006046510.018
odontogenesisGO:0042476780.018
ear morphogenesisGO:00424711180.018
exocytosisGO:00068871210.018
brain segmentationGO:003528430.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
alcohol metabolic processGO:00060661160.018
positive regulation of organelle organizationGO:00106381280.018
regulation of carbohydrate metabolic processGO:0006109750.018
endocrine system developmentGO:0035270980.017
carbohydrate biosynthetic processGO:0016051740.017
forebrain cell migrationGO:0021885580.017
regulation of hydrolase activityGO:00513362460.017
regulation of cell motilityGO:20001452360.017
negative regulation of cell proliferationGO:00082852960.017
response to growth factorGO:00708481980.017
t cell activationGO:00421102890.017
membrane organizationGO:00610242450.017
regulation of cell activationGO:00508652890.017
positive regulation of cell deathGO:00109422240.017
mammary placode formationGO:006059640.017
mesodermal cell migrationGO:000807840.017
bmp signaling pathwayGO:0030509930.017
regulation of wnt signaling pathwayGO:00301111230.017
tendon formationGO:003599240.017
chemotaxisGO:00069352470.017
adaptive immune responseGO:00022501550.017
cytoplasmic transportGO:00164822340.017
neuromuscular processGO:0050905990.017
cation transportGO:00068123990.017
mitral valve morphogenesisGO:000318340.017
synaptic transmissionGO:00072683290.017
modification dependent macromolecule catabolic processGO:00436321330.017
homeostasis of number of cellsGO:00488722100.017
g protein coupled receptor signaling pathwayGO:00071862430.017
cell recognitionGO:0008037830.017
phospholipid metabolic processGO:0006644870.016
cerebral cortex cell migrationGO:0021795440.016
regulation of lymphocyte activationGO:00512492400.016
mesenchymal cell differentiationGO:00487621070.016
negative regulation of protein metabolic processGO:00512482820.016
skeletal muscle organ developmentGO:00605381630.016
organophosphate biosynthetic processGO:00904071220.016
regulation of cardiac chamber morphogenesisGO:190121920.016
exocrine system developmentGO:0035272450.016
fat cell differentiationGO:00454441600.016
developmental maturationGO:00217001930.016
regulation of transcription from rna polymerase iii promoterGO:000635920.016
response to peptideGO:19016521360.016
cranial nerve developmentGO:0021545410.016
gonad developmentGO:00084061410.016
trophectodermal cell differentiationGO:0001829210.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
purine containing compound catabolic processGO:00725232130.015
nuclear divisionGO:00002801580.015
epithelial cell proliferationGO:00506731740.015
actin cytoskeleton organizationGO:00300362200.015
regulation of asymmetric cell divisionGO:000978640.015
pigmentationGO:0043473710.015
regulation of protein localizationGO:00328802310.015
transdifferentiationGO:006029010.015
positive regulation of cell activationGO:00508671580.015
cellular protein catabolic processGO:00442571550.015
positive regulation of lymphocyte activationGO:00512511400.015
regulation of striated muscle cell differentiationGO:0051153810.015
bone developmentGO:00603481200.015
oocyte axis specificationGO:000730920.015
peptide secretionGO:00027901140.015
multicellular organismal signalingGO:0035637910.015
palate developmentGO:0060021760.015
cardiac muscle tissue morphogenesisGO:0055008440.015
embryonic appendage morphogenesisGO:00351131260.015
positive regulation of actin nucleationGO:005112730.015
response to nutrient levelsGO:00316671090.015
forebrain generation of neuronsGO:0021872630.015
multicellular organismal homeostasisGO:00488711640.015
rna processingGO:00063961050.015
protein alkylationGO:0008213810.014
regulation of embryonic developmentGO:0045995710.014
cellular lipid metabolic processGO:00442553230.014
regulation of actin nucleationGO:005112540.014
male gonad developmentGO:0008584880.014
axon guidanceGO:00074111410.014
cellular response to growth factor stimulusGO:00713631970.014
cardiac chamber developmentGO:00032051080.014
cellular response to dna damage stimulusGO:00069742070.014
Mouse
bone morphogenesisGO:0060349780.014
blood circulationGO:00080151950.014
positive regulation of mesoderm developmentGO:200038220.014
regulation of transferase activityGO:00513382630.014
positive regulation of transferase activityGO:00513471670.014
purine ribonucleotide metabolic processGO:00091502900.014
maintenance of locationGO:0051235890.014
modification dependent protein catabolic processGO:00199411330.014
intracellular receptor signaling pathwayGO:0030522740.014
nephron developmentGO:00720061090.014
cerebellum developmentGO:0021549770.014
response to insulinGO:00328681000.014
regulation of glucose metabolic processGO:0010906600.014
lipid localizationGO:00108761260.014
telencephalon cell migrationGO:0022029550.014
bundle of his developmentGO:000316640.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
erythrocyte differentiationGO:0030218880.014
forebrain radial glial cell differentiationGO:002186140.014
limb morphogenesisGO:00351081490.014
megakaryocyte differentiationGO:0030219260.014
regulation of t cell activationGO:00508631700.013
specification of organ positionGO:001015930.013
negative regulation of myeloid cell differentiationGO:0045638380.013
regulation of multi organism processGO:00439001110.013
response to oxygen levelsGO:0070482620.013
mitochondrion organizationGO:00070051340.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
Mouse
somatotropin secreting cell developmentGO:006013320.013
t cell differentiationGO:00302171740.013
cellular nitrogen compound catabolic processGO:00442702800.013
metencephalon developmentGO:0022037890.013
ventricular cardiac muscle tissue developmentGO:0003229380.013
segmentationGO:0035282930.013
motor neuron migrationGO:009747540.013
nucleotide catabolic processGO:00091662170.013
ossificationGO:00015032160.013
regulation of ras protein signal transductionGO:00465781140.013
epidermis developmentGO:00085441870.013
wnt signaling pathwayGO:00160551880.013
immune effector processGO:00022523210.013
small molecule catabolic processGO:0044282710.013
regulation of actin cytoskeleton organizationGO:0032956840.013
neuronal action potentialGO:0019228540.013
nucleoside phosphate metabolic processGO:00067533380.013
regulation of fat cell differentiationGO:0045598810.013
cellular response to amino acid stimulusGO:0071230290.013
myeloid cell homeostasisGO:00022621140.013
intestinal epithelial structure maintenanceGO:006072940.013
central nervous system segmentationGO:003528330.013
peptide hormone secretionGO:00300721090.013
nucleocytoplasmic transportGO:00069131390.013
nuclear transportGO:00511691390.013
digestive tract morphogenesisGO:00485461470.013
mechanoreceptor differentiationGO:0042490670.013
respiratory system developmentGO:00605411900.013
regulation of secretionGO:00510462740.013
cardiac chamber morphogenesisGO:0003206930.013
regulation of skeletal muscle fiber differentiationGO:190280930.013
gene silencingGO:0016458380.013
mesoderm formationGO:0001707620.013
lipid transportGO:0006869980.013
multicellular organism growthGO:00352641610.013
regulation of chromatin organizationGO:1902275570.012
ribose phosphate metabolic processGO:00196932910.012
oocyte constructionGO:000730820.012
cell differentiation in spinal cordGO:0021515530.012
determination of left right symmetryGO:0007368800.012
regulation of neural retina developmentGO:006107430.012
mesoderm morphogenesisGO:0048332640.012
response to oxidative stressGO:00069791230.012
morphogenesis of a polarized epitheliumGO:0001738370.012
rho protein signal transductionGO:0007266320.012
thick ascending limb developmentGO:007202320.012
autonomic nervous system developmentGO:0048483430.012
mitotic cell cycleGO:00002781950.012
positive regulation of skeletal muscle cell differentiationGO:200101640.012
negative regulation of protein phosphorylationGO:00019331260.012
appendage developmentGO:00487361660.012
neural crest cell developmentGO:0014032480.012
sensory perception of soundGO:0007605970.012
asymmetric neuroblast divisionGO:005505910.012
regulation of auditory receptor cell differentiationGO:004560740.012
organelle localizationGO:00516401790.012
spinal cord developmentGO:0021510810.012
neural retina developmentGO:0003407410.012
regulation of cytokine productionGO:00018172660.012
intracellular protein transportGO:00068862040.012
negative regulation of neuron deathGO:1901215980.012
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.012
regulation of angiogenesisGO:0045765810.012
regulation of kinase activityGO:00435492490.012
muscle cell developmentGO:00550011330.012
tongue muscle cell differentiationGO:003598120.012
endodermal cell fate specificationGO:000171440.012
regulation of cellular component biogenesisGO:00440871810.012
regulation of myotube differentiationGO:0010830620.012
negative regulation of transferase activityGO:0051348850.012
anatomical structure homeostasisGO:00602491450.012
transmembrane transportGO:00550854120.012
histone h3 k4 methylationGO:0051568230.012
blastocyst growthGO:0001832230.012
negative regulation of kinase activityGO:0033673810.012
amide transportGO:00428861380.012
cytokine productionGO:00018163190.012
meiotic nuclear divisionGO:00071261150.012
purine nucleotide metabolic processGO:00061633020.012
establishment of protein localization to organelleGO:00725941180.012
regulation of lymphocyte differentiationGO:00456191070.012
sensory perception of mechanical stimulusGO:00509541070.012
glucose metabolic processGO:0006006920.012
positive regulation of cell motilityGO:20001471160.012
regulation of cellular response to stressGO:00801351590.011
Mouse
blood vessel remodelingGO:0001974330.011
response to extracellular stimulusGO:00099911270.011
leukocyte migrationGO:00509001240.011
apoptotic mitochondrial changesGO:0008637480.011
actin polymerization or depolymerizationGO:0008154540.011
cerebellar granule cell precursor proliferationGO:0021930100.011
carbohydrate derivative biosynthetic processGO:19011371830.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
regulation of defense responseGO:00313472330.011
positive regulation of leukocyte differentiationGO:1902107860.011
cellular response to peptide hormone stimulusGO:0071375920.011
negative regulation of cardiac chamber morphogenesisGO:190122020.011
cellular amine metabolic processGO:0044106440.011
organic hydroxy compound biosynthetic processGO:1901617770.011
peripheral nervous system neuron axonogenesisGO:004893630.011
response to amino acidGO:0043200370.011
cellular homeostasisGO:00197252400.011
positive regulation of protein phosphorylationGO:00019342420.011
organic cyclic compound catabolic processGO:19013612950.011
internal peptidyl lysine acetylationGO:0018393420.011
lipid modificationGO:0030258650.011
zygotic determination of anterior posterior axis embryoGO:000735430.011
regulation of vesicle mediated transportGO:00606271390.011
cell activation involved in immune responseGO:00022631260.011
columnar cuboidal epithelial cell differentiationGO:0002065820.011
circadian rhythmGO:00076231140.011
positive regulation of stem cell proliferationGO:2000648590.011
steroid metabolic processGO:00082021190.011
cell divisionGO:00513011200.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
fertilizationGO:00095661270.011
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.011
positive regulation of skeletal muscle fiber differentiationGO:190281120.011
negative regulation of ossificationGO:0030279490.011
extracellular structure organizationGO:00430621480.011
intracellular mrna localizationGO:000829840.011
protein localization to nucleusGO:00345041210.011
positive regulation of t cell activationGO:00508701010.011
organic acid catabolic processGO:0016054510.011
carbon catabolite activation of transcriptionGO:004599140.011
muscle tissue morphogenesisGO:0060415530.011
ubiquitin dependent protein catabolic processGO:00065111290.011
leukocyte activation involved in immune responseGO:00023661260.011
rna splicingGO:0008380540.011
cardiac muscle cell differentiationGO:0055007690.011
limbic system developmentGO:0021761720.011
heterocycle catabolic processGO:00467002800.011
regulation of histone modificationGO:0031056560.011
regulation of establishment of protein localizationGO:00702011810.011
rac protein signal transductionGO:0016601130.011
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082910.011
regulation of protein transportGO:00512231630.011
glycogen metabolic processGO:0005977320.011
limb developmentGO:00601731660.011
response to starvationGO:0042594650.011
regulation of bindingGO:00510981110.011
regulation of cellular carbohydrate metabolic processGO:0010675750.011
cellular response to abiotic stimulusGO:0071214560.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
single organism cell adhesionGO:00986021560.011
canonical wnt signaling pathwayGO:00600701300.010
positive regulation of immune effector processGO:00026991070.010
regulation of system processGO:00440572000.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
ventral spinal cord developmentGO:0021517480.010
ectodermal cell differentiationGO:001066830.010
carboxylic acid catabolic processGO:0046395510.010
regulation of protein complex assemblyGO:0043254830.010
regulation of purine nucleotide metabolic processGO:19005421690.010
response to inorganic substanceGO:0010035960.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
regulation of mesenchymal cell proliferation involved in ureter developmentGO:007219930.010
embryonic skeletal system developmentGO:00487061200.010
cellular response to oxidative stressGO:0034599760.010
regulation of peptide secretionGO:0002791770.010
positive regulation of keratinocyte proliferationGO:001083840.010
skeletal muscle cell differentiationGO:0035914660.010
nucleoside triphosphate metabolic processGO:00091412300.010
smad protein complex assemblyGO:000718310.010
meiosis iGO:0007127600.010
pituitary gland developmentGO:0021983380.010
embryonic limb morphogenesisGO:00303261260.010
somitogenesisGO:0001756690.010
ear developmentGO:00435832000.010
regulation of nucleoside metabolic processGO:00091181300.010
formation of organ boundaryGO:001016010.010

Hic2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
disease of cellular proliferationDOID:1456600.016
eye diseaseDOID:561400.012
retinal degenerationDOID:846600.012
eye and adnexa diseaseDOID:149200.012
retinal diseaseDOID:567900.012
sensory system diseaseDOID:005015500.012
disease of metabolismDOID:001466700.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012