Mus musculus

34 known processes

Adam15

a disintegrin and metallopeptidase domain 15 (metargidin)

(Aliases: metargidin,MDC15)

Adam15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of membrane protein ectodomain proteolysisGO:005104430.891
Mouse
prevention of polyspermyGO:006046840.880
Mouse
fibronectin dependent thymocyte migrationGO:007268110.845
Mouse
extracellular matrix dependent thymocyte migrationGO:007268010.771
Mouse
thymocyte migrationGO:007267920.675
Mouse
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.670
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.667
regulation of fibronectin dependent thymocyte migrationGO:200041310.615
Mouse
regulation of thymocyte migrationGO:200041020.609
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.492
Mouse
positive regulation of eosinophil migrationGO:200041820.484
Mouse
regulation of membrane protein ectodomain proteolysisGO:005104330.469
Mouse
regulation of cell motilityGO:20001452360.427
Human Mouse
regulation of t cell activationGO:00508631700.415
Mouse
positive regulation of mapk cascadeGO:00434101700.410
Mouse
myeloid cell homeostasisGO:00022621140.353
Mouse
response to organic cyclic compoundGO:00140701980.342
Mouse
positive regulation of protein kinase activityGO:00458601440.318
Mouse
locomotory behaviorGO:00076261950.308
Mouse
lymphocyte differentiationGO:00300982420.303
Mouse
mapk cascadeGO:00001652810.290
Mouse
cation transportGO:00068123990.286
learning or memoryGO:00076111480.284
Mouse
t cell activationGO:00421102890.271
Mouse
germinal center formationGO:0002467160.263
Mouse
regulation of t cell differentiationGO:0045580830.260
Mouse
regulation of eosinophil migrationGO:200041620.259
Mouse
striated muscle tissue developmentGO:00147062930.254
eosinophil migrationGO:007267730.250
Mouse
t cell differentiationGO:00302171740.248
Mouse
positive regulation of kinase activityGO:00336741550.247
Mouse
nucleoside phosphate metabolic processGO:00067533380.247
muscle tissue developmentGO:00605373080.243
angiogenesisGO:00015252010.234
Mouse
cellular amino acid metabolic processGO:00065201030.233
membrane protein proteolysisGO:0033619100.223
Mouse
regulation of lymphocyte differentiationGO:00456191070.223
Mouse
transmembrane transportGO:00550854120.222
transmission of nerve impulseGO:0019226760.219
Mouse
glycoprotein biosynthetic processGO:0009101890.207
ion transmembrane transportGO:00342203610.207
b cell activationGO:00421131610.204
Mouse
cellular response to growth factor stimulusGO:00713631970.203
Mouse
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.198
Mouse
positive regulation of homeostatic processGO:0032846640.189
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.189
Mouse
cognitionGO:00508901490.186
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.185
Mouse
leukocyte migrationGO:00509001240.182
Mouse
response to light stimulusGO:00094161350.180
Mouse
regulation of cell migrationGO:00303342190.179
Human Mouse
myelination in peripheral nervous systemGO:0022011190.178
Mouse
ribose phosphate metabolic processGO:00196932910.178
schwann cell developmentGO:0014044220.178
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.175
Mouse
positive regulation of protein modification processGO:00314012990.172
Mouse
protein localization to membraneGO:00726571080.172
pma inducible membrane protein ectodomain proteolysisGO:005108810.170
Mouse
stem cell differentiationGO:00488632680.167
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.163
Mouse
regulation of protein catabolic processGO:00421761080.162
Mouse
regulation of leukocyte differentiationGO:19021051590.162
Mouse
cation transmembrane transportGO:00986552660.161
macromolecule glycosylationGO:0043413550.157
leukocyte differentiationGO:00025213420.154
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560880.151
Mouse
inflammatory responseGO:00069542440.151
Mouse
granulocyte migrationGO:0097530430.148
Mouse
regulation of cellular amine metabolic processGO:0033238200.147
positive regulation of bone resorptionGO:0045780130.145
Mouse
purine containing compound metabolic processGO:00725213110.144
regulation of transferase activityGO:00513382630.142
Mouse
inorganic cation transmembrane transportGO:00986622070.142
cardiac muscle tissue developmentGO:00487381300.141
positive regulation of bone remodelingGO:0046852130.141
Mouse
anion transportGO:00068201770.140
response to growth factorGO:00708481980.137
Mouse
glycoprotein metabolic processGO:00091001160.137
positive regulation of t cell differentiationGO:0045582520.132
Mouse
protein kinase b signalingGO:0043491740.130
Mouse
regulation of cell activationGO:00508652890.129
Mouse
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.129
Mouse
regulation of lymphocyte activationGO:00512492400.128
Mouse
multicellular organismal signalingGO:0035637910.125
Mouse
establishment of vesicle localizationGO:0051650810.124
anatomical structure homeostasisGO:00602491450.124
Mouse
spleen developmentGO:0048536390.121
Mouse
visual behaviorGO:0007632450.121
Mouse
response to radiationGO:00093141650.120
Mouse
regulation of protein kinase activityGO:00458592320.120
Mouse
positive regulation of nf kappab transcription factor activityGO:0051092300.119
Mouse
divalent inorganic cation transportGO:00725111780.119
positive regulation of lymphocyte activationGO:00512511400.118
Mouse
calcium ion transportGO:00068161590.117
response to peptideGO:19016521360.117
t cell differentiation in thymusGO:0033077770.116
Mouse
positive regulation of t cell activationGO:00508701010.115
Mouse
regulation of kinase activityGO:00435492490.112
Mouse
divalent metal ion transportGO:00708381720.109
neuronal action potentialGO:0019228540.108
Mouse
positive regulation of cell migrationGO:00303351090.108
Mouse
regulation of multi organism processGO:00439001110.107
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.107
membrane organizationGO:00610242450.105
cellular amine metabolic processGO:0044106440.102
regulation of ion transportGO:00432692150.101
chemotaxisGO:00069352470.101
Mouse
skeletal system morphogenesisGO:00487052030.100
neuron apoptotic processGO:00514021420.100
Mouse
positive regulation of inflammatory responseGO:0050729470.099
Mouse
activation of mapk activityGO:0000187590.099
Mouse
positive regulation of cell motilityGO:20001471160.098
Mouse
multicellular organismal homeostasisGO:00488711640.097
Mouse
myeloid cell apoptotic processGO:0033028220.096
Mouse
positive regulation of tissue remodelingGO:0034105190.095
Mouse
regulation of intracellular transportGO:00323861590.093
activation of innate immune responseGO:0002218560.093
Mouse
positive regulation of cell deathGO:00109422240.093
Mouse
regulation of myotube differentiationGO:0010830620.092
cellular chemical homeostasisGO:00550822150.092
establishment of protein localization to membraneGO:0090150540.091
small gtpase mediated signal transductionGO:0007264970.090
regulation of membrane potentialGO:00423911920.090
Mouse
myelinationGO:0042552740.089
Mouse
positive regulation of apoptotic processGO:00430652170.087
Mouse
cell adhesionGO:00071553290.086
Human Mouse
nucleotide metabolic processGO:00091173320.086
binding of sperm to zona pellucidaGO:0007339340.086
Mouse
inorganic ion transmembrane transportGO:00986602340.086
regulation of neuron apoptotic processGO:00435231220.084
Mouse
synaptic vesicle transportGO:0048489570.083
glial cell developmentGO:0021782540.083
Mouse
positive regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030910.083
Mouse
visual learningGO:0008542440.083
Mouse
cellular carbohydrate metabolic processGO:00442621190.083
immune response activating signal transductionGO:00027571160.082
Mouse
cell cell recognitionGO:0009988440.081
Mouse
actin cytoskeleton organizationGO:00300362200.081
organic anion transportGO:00157111370.080
sodium ion transportGO:0006814730.080
aromatic compound catabolic processGO:00194392860.079
organophosphate biosynthetic processGO:00904071220.079
activation of immune responseGO:00022531380.078
Mouse
macromolecule catabolic processGO:00090572810.077
Mouse
carbohydrate biosynthetic processGO:0016051740.077
response to peptide hormoneGO:00434341270.077
positive regulation of cell adhesionGO:0045785800.076
Mouse
regulation of cellular amino acid metabolic processGO:000652150.076
guanosine containing compound metabolic processGO:19010681440.076
carbohydrate metabolic processGO:00059752300.076
cellular metal ion homeostasisGO:00068751510.076
blood circulationGO:00080151950.075
single fertilizationGO:0007338820.075
Mouse
cell junction organizationGO:0034330770.074
action potentialGO:0001508780.074
Mouse
regulation of response to woundingGO:19030341890.074
Mouse
positive regulation of leukocyte differentiationGO:1902107860.074
Mouse
positive regulation of cellular catabolic processGO:00313311480.074
Mouse
positive regulation of lymphocyte differentiationGO:0045621610.072
Mouse
bone developmentGO:00603481200.072
schwann cell differentiationGO:0014037260.071
Mouse
leukocyte chemotaxisGO:0030595690.071
Mouse
transforming growth factor beta receptor signaling pathwayGO:0007179710.071
Mouse
cellular ion homeostasisGO:00068731650.070
regulation of ion transmembrane transporter activityGO:0032412540.070
mucopolysaccharide metabolic processGO:1903510250.070
regulation of protein serine threonine kinase activityGO:00719001570.070
Mouse
skeletal system developmentGO:00015013560.069
adult locomotory behaviorGO:0008344910.068
Mouse
oxidation reduction processGO:00551143420.067
positive regulation of intracellular transportGO:0032388700.067
regulation of protein localizationGO:00328802310.067
associative learningGO:0008306610.066
Mouse
regulation of mapk cascadeGO:00434082480.066
Mouse
muscle contractionGO:00069361010.066
regulation of homeostatic processGO:00328441820.065
Mouse
negative regulation of protein metabolic processGO:00512482820.065
endomembrane system organizationGO:00102561470.065
single organism cell adhesionGO:00986021560.063
Mouse
developmental maturationGO:00217001930.063
learningGO:0007612980.063
Mouse
regulation of cellular catabolic processGO:00313292420.063
Mouse
leukocyte homeostasisGO:0001776790.063
Mouse
protein catabolic processGO:00301632210.063
Mouse
cellular response to insulin stimulusGO:0032869780.062
negative regulation of leukocyte differentiationGO:1902106510.062
myeloid cell differentiationGO:00300992330.061
axonogenesisGO:00074092740.061
mesenchymal cell developmentGO:0014031930.061
blood vessel morphogenesisGO:00485142850.060
Mouse
plasma membrane organizationGO:0007009900.060
positive regulation of protein serine threonine kinase activityGO:00719021060.059
Mouse
glycosyl compound metabolic processGO:19016572460.059
cell chemotaxisGO:0060326810.059
Mouse
forebrain developmentGO:00309003020.059
organic acid transportGO:00158491010.059
regulation of secretion by cellGO:19035302490.059
leukocyte migration involved in inflammatory responseGO:000252370.058
Mouse
immune response regulating signaling pathwayGO:00027641250.058
Mouse
regulation of ion transmembrane transportGO:00347651190.058
chondrocyte differentiationGO:0002062720.058
purine ribonucleotide metabolic processGO:00091502900.058
gland developmentGO:00487323300.057
limb developmentGO:00601731660.057
adaptive immune responseGO:00022501550.057
Mouse
membrane protein ectodomain proteolysisGO:000650970.056
Mouse
regulation of tissue remodelingGO:0034103380.056
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.056
Mouse
positive regulation of protein phosphorylationGO:00019342420.055
Mouse
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.055
response to lipopolysaccharideGO:00324961280.055
regulation of transmembrane transportGO:00347621280.054
protein glycosylationGO:0006486550.053
positive regulation of response to woundingGO:1903036660.053
Mouse
cell substrate adhesionGO:00315891300.052
Human
cytosolic calcium ion transportGO:0060401480.052
acute inflammatory responseGO:0002526410.052
Mouse
embryonic organ morphogenesisGO:00485622760.052
carboxylic acid transportGO:00469421000.052
lung developmentGO:00303241640.051
peptidyl amino acid modificationGO:00181933360.051
positive regulation of nervous system developmentGO:00519622210.051
egg activationGO:000734370.051
Mouse
negative regulation of neuron apoptotic processGO:0043524920.051
Mouse
response to drugGO:0042493750.051
Mouse
neuron deathGO:00709971540.050
Mouse
regulation of bone remodelingGO:0046850280.050
Mouse
regulation of cytokine productionGO:00018172660.050
Mouse
regulation of transporter activityGO:0032409570.049
innate immune responseGO:00450871570.049
Human Mouse
axon ensheathmentGO:0008366760.049
Mouse
positive regulation of cellular amine metabolic processGO:003324050.049
positive regulation of secretionGO:00510471300.048
single organismal cell cell adhesionGO:00163371310.048
Mouse
homeostasis of number of cellsGO:00488722100.048
Mouse
innate immune response activating signal transductionGO:0002758500.047
Mouse
amine metabolic processGO:0009308450.047
leukocyte apoptotic processGO:0071887710.047
Mouse
positive regulation of proteolysisGO:0045862850.047
Mouse
positive regulation of secretion by cellGO:19035321140.046
male gamete generationGO:00482322850.046
synaptic transmissionGO:00072683290.046
gtp catabolic processGO:00061841430.046
purine nucleotide metabolic processGO:00061633020.045
regulation of mast cell apoptotic processGO:003302550.045
Mouse
calcium ion transmembrane transportGO:0070588850.045
acylglycerol metabolic processGO:0006639550.045
regulation of t cell differentiation in thymusGO:0033081240.045
Mouse
response to extracellular stimulusGO:00099911270.044
cardiocyte differentiationGO:0035051870.044
maintenance of locationGO:0051235890.044
cellular extravasationGO:0045123170.044
Mouse
cellular ketone metabolic processGO:0042180840.044
renal system developmentGO:00720012250.044
regulation of map kinase activityGO:00434051200.043
Mouse
striated muscle contractionGO:0006941450.043
b cell differentiationGO:0030183780.043
Mouse
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.043
Mouse
ensheathment of neuronsGO:0007272760.043
Mouse
negative regulation of cellular amine metabolic processGO:003323910.043
cd4 positive alpha beta t cell activationGO:0035710450.043
positive regulation of transferase activityGO:00513471670.043
Mouse
sensory perceptionGO:00076002450.043
glycosylationGO:0070085620.042
positive regulation of protein kinase b signalingGO:0051897320.042
Mouse
circulatory system processGO:00030131970.042
peptide transportGO:00158331330.042
regulation of protein kinase b signalingGO:0051896560.042
Mouse
response to inorganic substanceGO:0010035960.042
regulation of cytoskeleton organizationGO:00514931220.041
lipid transportGO:0006869980.041
peptidyl serine modificationGO:0018209830.041
sensory perception of chemical stimulusGO:0007606510.040
inner ear receptor cell developmentGO:0060119390.040
regulation of apoptotic signaling pathwayGO:20012331970.040
positive regulation of protein catabolic processGO:0045732600.040
Mouse
urogenital system developmentGO:00016552610.040
male gonad developmentGO:0008584880.039
positive regulation of programmed cell deathGO:00430682180.039
Mouse
peptidyl serine phosphorylationGO:0018105740.039
cellular lipid metabolic processGO:00442553230.039
nucleoside phosphate biosynthetic processGO:1901293790.038
limb morphogenesisGO:00351081490.038
bone morphogenesisGO:0060349780.038
regulation of feeding behaviorGO:006025930.038
tumor necrosis factor ligand superfamily member 11 productionGO:007253510.038
Mouse
nephron developmentGO:00720061090.037
organonitrogen compound biosynthetic processGO:19015661920.037
regulation of actin filament based processGO:0032970990.037
intracellular protein transportGO:00068862040.037
regulation of cellular response to stressGO:00801351590.037
cation homeostasisGO:00550802120.037
cell cell junction organizationGO:0045216720.037
purine ribonucleoside triphosphate metabolic processGO:00092052200.037
regulation of muscle system processGO:0090257800.036
regulation of cell projection organizationGO:00313442060.036
cellular response to hormone stimulusGO:00328701500.036
camp metabolic processGO:0046058400.036
endocytosisGO:00068971680.036
regulation of proteolysisGO:00301621640.036
Mouse
regulation of cellular ketone metabolic processGO:0010565660.036
polysaccharide biosynthetic processGO:0000271200.036
response to transforming growth factor betaGO:0071559880.035
Mouse
carbohydrate derivative catabolic processGO:19011362310.035
neutral lipid metabolic processGO:0006638570.035
skeletal muscle organ developmentGO:00605381630.035
regulation of system processGO:00440572000.035
lipid localizationGO:00108761260.035
glycerolipid metabolic processGO:00464861220.035
sensory perception of smellGO:0007608260.035
negative regulation of intracellular signal transductionGO:19025321670.034
regulation of ossificationGO:00302781120.034
negative regulation of molecular functionGO:00440922580.034
Human
regulation of leukocyte apoptotic processGO:2000106560.034
Mouse
ribonucleoside metabolic processGO:00091192450.033
bone resorptionGO:0045453380.033
Mouse
establishment of synaptic vesicle localizationGO:0097480570.033
negative regulation of phosphorus metabolic processGO:00105631840.032
regulation of secretionGO:00510462740.032
male sex differentiationGO:00466611090.032
nucleoside catabolic processGO:00091642060.032
cellular component assembly involved in morphogenesisGO:00109271390.032
circadian temperature homeostasisGO:006008620.032
t cell apoptotic processGO:0070231390.032
Mouse
positive regulation of thymocyte apoptotic processGO:007024550.032
Mouse
sperm egg recognitionGO:0035036370.031
Mouse
aminoglycan metabolic processGO:0006022340.031
ear developmentGO:00435832000.031
cellular response to cytokine stimulusGO:00713451890.031
myotube differentiationGO:00149021050.031
purine nucleotide biosynthetic processGO:0006164650.031
regulation of defense responseGO:00313472330.031
Mouse
regulation of organelle organizationGO:00330432890.031
sphingolipid metabolic processGO:0006665450.031
filopodium assemblyGO:0046847190.030
epithelial cell developmentGO:00020641590.030
nucleoside metabolic processGO:00091162460.030
neutrophil migrationGO:1990266370.029
nitrogen compound transportGO:00717052710.029
protein localization to plasma membraneGO:0072659570.029
sulfur compound biosynthetic processGO:0044272370.029
ras protein signal transductionGO:0007265770.029
organophosphate catabolic processGO:00464342320.029
positive regulation of acute inflammatory responseGO:0002675160.029
Mouse
positive regulation of defense responseGO:00313491240.029
Mouse
stem cell maintenanceGO:00198271300.028
regulation of vesicle mediated transportGO:00606271390.028
ribonucleotide catabolic processGO:00092612080.028
purine nucleoside metabolic processGO:00422782410.028
positive regulation of cell developmentGO:00107202370.028
ribonucleoside triphosphate metabolic processGO:00091992200.028
carboxylic acid catabolic processGO:0046395510.028
regulation of intracellular protein transportGO:0033157820.028
glycosaminoglycan biosynthetic processGO:0006024150.027
monocarboxylic acid transportGO:0015718440.027
regulation of metal ion transportGO:00109591060.027
lymphocyte apoptotic processGO:0070227540.027
Mouse
regulation of lymphocyte apoptotic processGO:0070228410.027
Mouse
nucleotide biosynthetic processGO:0009165780.027
establishment of organelle localizationGO:00516561220.027
female sex differentiationGO:0046660840.027
receptor mediated endocytosisGO:0006898510.027
sulfur compound metabolic processGO:00067901000.027
regulation of muscle tissue developmentGO:1901861970.027
endochondral bone morphogenesisGO:0060350500.027
regulation of neuron deathGO:19012141340.027
Mouse
small molecule catabolic processGO:0044282710.027
sequestering of calcium ionGO:0051208180.027
cytokine mediated signaling pathwayGO:00192211150.027
regulation of cell shapeGO:0008360390.026
ossificationGO:00015032160.026
heart processGO:0003015940.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
cell fate commitmentGO:00451652100.026
positive regulation of calcium ion transportGO:0051928270.026
tumor necrosis factor superfamily cytokine productionGO:0071706510.026
Mouse
regulation of bone resorptionGO:0045124240.026
Mouse
cellular lipid catabolic processGO:0044242520.026
cellular homeostasisGO:00197252400.026
regulation of myeloid cell apoptotic processGO:0033032190.026
Mouse
negative regulation of cell developmentGO:00107211690.026
extracellular matrix organizationGO:00301981470.026
muscle system processGO:00030121410.026
purine ribonucleotide catabolic processGO:00091542080.026
response to organonitrogen compoundGO:00102432460.025
immune effector processGO:00022523210.025
negative regulation of carbohydrate metabolic processGO:0045912190.025
negative regulation of cell fate specificationGO:000999640.025
chondrocyte developmentGO:0002063240.025
positive regulation of glucose transportGO:0010828160.025
basement membrane organizationGO:007171180.025
respiratory tube developmentGO:00303231670.025
development of primary male sexual characteristicsGO:0046546880.025
tissue homeostasisGO:00018941150.025
Mouse
positive regulation of cytokine productionGO:00018191740.025
Mouse
organelle assemblyGO:00709251770.025
camp biosynthetic processGO:0006171310.025
regulation of thymocyte apoptotic processGO:0070243140.025
Mouse
appendage morphogenesisGO:00351071490.025
mitochondrion organizationGO:00070051340.025
regulation of acute inflammatory responseGO:0002673270.025
Mouse
positive regulation of ion transportGO:0043270650.025
regulation of inflammatory responseGO:00507271470.024
Mouse
cellular response to organonitrogen compoundGO:00714171450.024
fertilizationGO:00095661270.024
Mouse
regulation of skeletal muscle fiber developmentGO:0048742360.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
establishment of protein localization to organelleGO:00725941180.024
negative regulation of cellular component organizationGO:00511291940.024
organic acid catabolic processGO:0016054510.024
regulation of calcium ion transportGO:0051924690.024
negative regulation of phosphate metabolic processGO:00459361840.024
purine ribonucleoside metabolic processGO:00461282410.024
vesicle localizationGO:0051648860.023
development of primary female sexual characteristicsGO:0046545730.023
organelle localizationGO:00516401790.023
rhythmic processGO:00485111740.023
protein maturationGO:00516041760.023
development of primary sexual characteristicsGO:00451371430.023
polysaccharide metabolic processGO:0005976390.023
synaptic vesicle localizationGO:0097479590.023
purine containing compound biosynthetic processGO:0072522700.023
tissue remodelingGO:00487711020.023
Mouse
regulation of calcium ion transmembrane transportGO:1903169200.023
purine nucleoside catabolic processGO:00061522050.023
regulation of nucleocytoplasmic transportGO:0046822730.023
regulation of cell cycleGO:00517262810.022
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.022
Mouse
sequestering of metal ionGO:0051238190.022
skin developmentGO:00435882200.022
neuron projection extensionGO:1990138640.022
energy derivation by oxidation of organic compoundsGO:0015980770.022
monosaccharide metabolic processGO:00059961060.022
regulation of carbohydrate metabolic processGO:0006109750.022
positive regulation of cell activationGO:00508671580.022
Mouse
skeletal muscle fiber developmentGO:0048741580.022
negative regulation of cellular amino acid metabolic processGO:004576300.022
positive regulation of thymocyte migrationGO:200041220.022
Mouse
cyclic nucleotide metabolic processGO:0009187590.022
germ cell developmentGO:00072811850.022
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189300.022
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.022
Mouse
positive regulation of lymphocyte apoptotic processGO:0070230130.021
Mouse
cartilage developmentGO:00512161400.021
regulation of alpha beta t cell activationGO:0046634530.021
response to nutrient levelsGO:00316671090.021
response to molecule of bacterial originGO:00022371430.021
lens development in camera type eyeGO:0002088620.021
cellular response to peptideGO:1901653920.021
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.021
Mouse
positive regulation of growthGO:00459271040.021
appendage developmentGO:00487361660.021
epidermis developmentGO:00085441870.021
adult behaviorGO:00305341350.021
Mouse
response to corticosteroidGO:0031960200.021
Mouse
purine ribonucleoside monophosphate metabolic processGO:0009167800.021
cellular phosphate ion homeostasisGO:003064320.021
regulation of cell substrate adhesionGO:0010810730.021
Human
negative regulation of neuron projection developmentGO:0010977500.021
epithelial cell migrationGO:0010631630.021
alpha beta t cell differentiationGO:0046632690.020
rac protein signal transductionGO:0016601130.020
regulation of myeloid cell differentiationGO:0045637960.020
extracellular structure organizationGO:00430621480.020
amide transportGO:00428861380.020
spermatid differentiationGO:00485151150.020
regulation of rho gtpase activityGO:0032319580.020
anion transmembrane transportGO:0098656710.020
monocarboxylic acid metabolic processGO:00327871910.020
negative regulation of cytokine productionGO:0001818840.020
positive regulation of leukocyte apoptotic processGO:2000108210.020
Mouse
digestive system developmentGO:00551232000.020
nucleoside triphosphate metabolic processGO:00091412300.020
negative regulation of cell motilityGO:2000146610.020
Human
granulocyte chemotaxisGO:0071621390.020
leukocyte activation involved in immune responseGO:00023661260.020
regulation of osteoclast differentiationGO:0045670360.019
regulation of cell growthGO:0001558910.019
Human
mast cell apoptotic processGO:003302450.019
Mouse
cell type specific apoptotic processGO:00972852680.019
Mouse
negative regulation of fertilizationGO:006046750.019
Mouse
mesenchymal cell differentiationGO:00487621070.019
camera type eye developmentGO:00430102660.019
fatty acid transmembrane transportGO:190200110.019
gtp metabolic processGO:00460391440.019
lipid catabolic processGO:0016042690.019
satellite cell activation involved in skeletal muscle regenerationGO:001490130.019

Adam15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.126
disease of anatomical entityDOID:700.126
muscular diseaseDOID:008000000.126
nervous system diseaseDOID:86300.086
disease of metabolismDOID:001466700.029
cardiovascular system diseaseDOID:128700.022
central nervous system diseaseDOID:33100.021
eye and adnexa diseaseDOID:149200.019
retinal diseaseDOID:567900.019
sensory system diseaseDOID:005015500.019
retinal degenerationDOID:846600.019
eye diseaseDOID:561400.019