Mus musculus

111 known processes

Adam17

a disintegrin and metallopeptidase domain 17

(Aliases: CD156b,Tace)

Adam17 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of mapk activity involved in innate immune responseGO:003541920.998
Mouse
neuron projection guidanceGO:00974851410.990
cell adhesionGO:00071553290.966
Human Mouse
cellular lipid metabolic processGO:00442553230.947
axon guidanceGO:00074111410.946
renal system developmentGO:00720012250.945
regulation of cellular amino acid metabolic processGO:000652150.940
cellular amino acid metabolic processGO:00065201030.927
extrinsic apoptotic signaling pathwayGO:00971911260.919
chemotaxisGO:00069352470.919
Human Mouse
heart processGO:0003015940.901
aminoglycan metabolic processGO:0006022340.884
rac protein signal transductionGO:0016601130.881
regulation of cellular amine metabolic processGO:0033238200.875
glial cell differentiationGO:00100011310.874
Mouse
mesonephric tubule developmentGO:0072164940.871
epithelial tube morphogenesisGO:00605623030.856
regulation of protein serine threonine kinase activityGO:00719001570.851
Human Mouse
stem cell differentiationGO:00488632680.846
Mouse
urogenital system developmentGO:00016552610.846
cell fate commitmentGO:00451652100.842
epidermis developmentGO:00085441870.841
kidney developmentGO:00018222130.840
leukocyte differentiationGO:00025213420.836
purine ribonucleotide metabolic processGO:00091502900.835
stem cell developmentGO:00488642190.834
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.830
Mouse
nucleoside triphosphate metabolic processGO:00091412300.829
circulatory system processGO:00030131970.822
purine nucleotide metabolic processGO:00061633020.810
regulation of t cell proliferationGO:0042129920.808
ribonucleotide metabolic processGO:00092592910.796
nucleoside phosphate metabolic processGO:00067533380.796
cellular ketone metabolic processGO:0042180840.793
ion transmembrane transportGO:00342203610.787
branching morphogenesis of an epithelial tubeGO:00487541590.785
positive regulation of nervous system developmentGO:00519622210.783
negative regulation of cell proliferationGO:00082852960.777
wnt signaling pathwayGO:00160551880.771
amine metabolic processGO:0009308450.768
regulation of mapk cascadeGO:00434082480.768
Mouse
carbon catabolite activation of transcriptionGO:004599140.763
regulation of kinase activityGO:00435492490.761
Human Mouse
mapk cascadeGO:00001652810.760
Mouse
blood circulationGO:00080151950.759
interleukin 11 mediated signaling pathwayGO:003815420.752
myeloid cell differentiationGO:00300992330.741
positive regulation of cell developmentGO:00107202370.735
organonitrogen compound biosynthetic processGO:19015661920.724
positive regulation of cellular amino acid metabolic processGO:004576430.714
positive regulation of mapk cascadeGO:00434101700.714
Mouse
peptidyl amino acid modificationGO:00181933360.710
Human
regulation of canonical wnt signaling pathwayGO:0060828820.695
respiratory system developmentGO:00605411900.683
cellular response to growth factor stimulusGO:00713631970.652
regulation of leukocyte proliferationGO:00706631210.650
regulation of myeloid cell differentiationGO:0045637960.648
organonitrogen compound catabolic processGO:19015652640.640
morphogenesis of a branching structureGO:00017632030.632
positive regulation of hydrolase activityGO:00513451480.621
ureteric bud developmentGO:0001657940.620
regulation of cell activationGO:00508652890.618
Mouse
glycosyl compound catabolic processGO:19016582060.617
cation transportGO:00068123990.613
leukocyte homeostasisGO:0001776790.610
carbohydrate metabolic processGO:00059752300.605
multicellular organism growthGO:00352641610.604
positive regulation of cell migrationGO:00303351090.603
Human Mouse
myeloid cell homeostasisGO:00022621140.602
regulation of t cell activationGO:00508631700.602
Mouse
protein localization to nucleusGO:00345041210.599
gliogenesisGO:00420631410.599
Mouse
lymphocyte homeostasisGO:0002260640.596
positive regulation of cell adhesionGO:0045785800.589
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.588
nucleoside phosphate catabolic processGO:19012922220.588
ribose phosphate metabolic processGO:00196932910.587
cellular modified amino acid metabolic processGO:0006575630.582
regulation of cell migrationGO:00303342190.577
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.573
Human
synaptic transmissionGO:00072683290.572
axonogenesisGO:00074092740.571
response to light stimulusGO:00094161350.570
Mouse
regulation of ion transportGO:00432692150.568
regulation of transferase activityGO:00513382630.564
Human Mouse
cytokine productionGO:00018163190.557
Human Mouse
response to radiationGO:00093141650.555
Mouse
germ cell developmentGO:00072811850.547
purine nucleoside metabolic processGO:00422782410.546
carbon catabolite regulation of transcriptionGO:004599040.544
blood vessel morphogenesisGO:00485142850.543
Mouse
regulation of tissue remodelingGO:0034103380.541
Mouse
mechanoreceptor differentiationGO:0042490670.535
positive regulation of protein modification processGO:00314012990.535
Human Mouse
regulation of hydrolase activityGO:00513362460.529
kidney epithelium developmentGO:00720731210.527
immune response regulating signaling pathwayGO:00027641250.525
Mouse
regulation of purine nucleotide metabolic processGO:19005421690.525
cell type specific apoptotic processGO:00972852680.524
proteoglycan biosynthetic processGO:0030166200.521
epithelial cell proliferationGO:00506731740.520
cellular amine metabolic processGO:0044106440.519
regulation of leukocyte differentiationGO:19021051590.518
Mouse
positive regulation of glial cell proliferationGO:006025240.516
b cell homeostasisGO:0001782340.514
regulation of protein kinase activityGO:00458592320.513
Human Mouse
tissue remodelingGO:00487711020.510
Mouse
cell chemotaxisGO:0060326810.509
Human Mouse
small gtpase mediated signal transductionGO:0007264970.508
skin developmentGO:00435882200.494
regulation of cell projection organizationGO:00313442060.493
extracellular structure organizationGO:00430621480.491
positive regulation of defense responseGO:00313491240.489
Mouse
regulation of peptidyl tyrosine phosphorylationGO:0050730930.487
Human
ribonucleoside catabolic processGO:00424542060.483
apoptotic signaling pathwayGO:00971903060.482
b cell activationGO:00421131610.481
neuron apoptotic processGO:00514021420.477
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.476
angiogenesisGO:00015252010.474
Mouse
regulation of nucleotide metabolic processGO:00061401690.471
nucleoside catabolic processGO:00091642060.470
lymphocyte proliferationGO:00466511640.467
nephron developmentGO:00720061090.466
positive regulation of programmed cell deathGO:00430682180.464
Mouse
single organismal cell cell adhesionGO:00163371310.462
Mouse
morphogenesis of a branching epitheliumGO:00611381930.461
positive regulation of cytokine productionGO:00018191740.461
Human Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.459
inflammatory responseGO:00069542440.456
Mouse
bone remodelingGO:0046849530.454
Mouse
camera type eye developmentGO:00430102660.454
positive regulation of cell deathGO:00109422240.452
Mouse
negative regulation of intracellular signal transductionGO:19025321670.451
extracellular matrix organizationGO:00301981470.445
leukocyte proliferationGO:00706611720.441
ribonucleotide catabolic processGO:00092612080.437
positive regulation of protein kinase b signalingGO:0051897320.434
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.429
regulation of map kinase activityGO:00434051200.425
Mouse
homeostasis of number of cellsGO:00488722100.424
regulation of osteoblast differentiationGO:0045667670.419
ventricular septum morphogenesisGO:0060412270.418
nucleotide metabolic processGO:00091173320.417
regulation of cellular component biogenesisGO:00440871810.414
transmembrane transportGO:00550854120.412
regulation of myeloid leukocyte differentiationGO:0002761580.412
actin filament organizationGO:00070151130.410
regulation of cell cycleGO:00517262810.410
Human
membrane organizationGO:00610242450.410
nephron tubule developmentGO:0072080840.409
regulation of proteolysisGO:00301621640.406
Mouse
regulation of neuron deathGO:19012141340.405
Mouse
regulation of lymphocyte proliferationGO:00506701170.401
alpha amino acid metabolic processGO:1901605590.400
purine containing compound metabolic processGO:00725213110.398
phospholipid metabolic processGO:0006644870.397
peptidyl tyrosine phosphorylationGO:00181081430.393
Human
regulation of cellular catabolic processGO:00313292420.392
Mouse
positive regulation of growthGO:00459271040.380
Human
organophosphate catabolic processGO:00464342320.377
purine nucleoside catabolic processGO:00061522050.372
formation of radial glial scaffoldsGO:002194340.372
lung developmentGO:00303241640.371
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.370
response to growth factorGO:00708481980.369
release of cytochrome c from mitochondriaGO:0001836230.367
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.367
Human
mesonephros developmentGO:0001823970.366
embryonic placenta developmentGO:0001892980.365
negative regulation of homeostatic processGO:0032845710.365
tissue homeostasisGO:00018941150.365
Mouse
protein catabolic processGO:00301632210.363
Mouse
oxidation reduction processGO:00551143420.362
regulation of neuron differentiationGO:00456642810.362
digestive tract developmentGO:00485651900.357
regulation of cell cycle processGO:00105641600.350
gtp catabolic processGO:00061841430.350
ossificationGO:00015032160.349
positive regulation of neuron projection regenerationGO:007057220.347
negative regulation of cellular protein metabolic processGO:00322692470.347
positive regulation of glial cell differentiationGO:0045687210.346
membrane protein ectodomain proteolysisGO:000650970.345
sensory organ morphogenesisGO:00905962420.345
clara cell differentiationGO:006048640.344
wound healing involved in inflammatory responseGO:000224640.344
wound healingGO:00420601570.343
Human
skeletal system morphogenesisGO:00487052030.343
mitochondrion organizationGO:00070051340.340
organic hydroxy compound metabolic processGO:19016152030.339
mesenchyme developmentGO:00604851520.339
Mouse
cellular response to carbohydrate stimulusGO:0071322500.335
cellular response to glucocorticoid stimulusGO:0071385130.335
cellular homeostasisGO:00197252400.331
positive regulation of cellular amine metabolic processGO:003324050.327
myeloid leukocyte differentiationGO:00025731190.326
regulation of cellular ketone metabolic processGO:0010565660.326
protein kinase b signalingGO:0043491740.325
Mouse
carbohydrate derivative catabolic processGO:19011362310.324
mesenchymal cell developmentGO:0014031930.323
Mouse
dendritic spine developmentGO:0060996300.322
cellular response to peptideGO:1901653920.321
oocyte constructionGO:000730820.321
regulation of mitotic cell cycleGO:00073461260.320
regulation of blood pressureGO:0008217930.319
regulation of cysteine type endopeptidase activityGO:2000116650.318
epithelial cell developmentGO:00020641590.316
embryonic organ morphogenesisGO:00485622760.314
cellular response to peptide hormone stimulusGO:0071375920.312
aromatic compound catabolic processGO:00194392860.311
divalent metal ion transportGO:00708381720.311
hormone biosynthetic processGO:0042446160.310
negative regulation of erk1 and erk2 cascadeGO:0070373210.305
positive regulation of innate immune responseGO:0045089800.305
Mouse
signal transduction in absence of ligandGO:0038034550.302
negative regulation of molecular functionGO:00440922580.300
negative regulation of phosphorylationGO:00423261660.299
multicellular organismal homeostasisGO:00488711640.298
Mouse
prostate gland morphogenesisGO:0060512320.298
bone resorptionGO:0045453380.297
Mouse
regulation of bone remodelingGO:0046850280.296
Mouse
glial cell developmentGO:0021782540.294
Mouse
cellular response to cytokine stimulusGO:00713451890.291
response to fibroblast growth factorGO:0071774470.290
chromatin organizationGO:00063252060.289
locomotory behaviorGO:00076261950.289
Mouse
cellular amide metabolic processGO:0043603580.289
t cell differentiation in thymusGO:0033077770.289
tyrosine phosphorylation of stat1 proteinGO:004250830.289
nucleotide catabolic processGO:00091662170.288
respiratory tube developmentGO:00303231670.287
carbohydrate derivative biosynthetic processGO:19011371830.287
regulation of cell migration involved in sprouting angiogenesisGO:009004940.287
regulation of erk1 and erk2 cascadeGO:0070372710.286
negative regulation of cellular amino acid metabolic processGO:004576300.285
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.285
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.282
glomerulus developmentGO:0032835400.281
nucleobase containing small molecule metabolic processGO:00550863520.281
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.280
neural precursor cell proliferationGO:00613511210.279
intracellular receptor signaling pathwayGO:0030522740.279
regulation of mitotic cell cycle phase transitionGO:1901990730.277
lymphocyte differentiationGO:00300982420.276
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.275
wnt signaling pathway involved in kidney developmentGO:006128920.272
negative regulation of protein metabolic processGO:00512482820.271
embryonic epithelial tube formationGO:00018381300.271
negative regulation of lymphocyte apoptotic processGO:0070229240.269
purine ribonucleoside triphosphate metabolic processGO:00092052200.268
regulation of cellular response to growth factor stimulusGO:0090287820.267
ovulation cycleGO:0042698590.267
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.266
regulation of rho protein signal transductionGO:0035023710.263
peptide metabolic processGO:0006518460.263
negative regulation of mapk cascadeGO:0043409650.262
nucleoside metabolic processGO:00091162460.260
hypoxia inducible factor 1alpha signaling pathwayGO:009741120.258
negative regulation of cellular component organizationGO:00511291940.256
regulation of homeostatic processGO:00328441820.255
organic cyclic compound catabolic processGO:19013612950.252
lung epithelium developmentGO:0060428370.251
ras protein signal transductionGO:0007265770.249
inflammatory response to woundingGO:009059440.249
ear developmentGO:00435832000.248
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiationGO:200072120.247
cellular divalent inorganic cation homeostasisGO:00725031270.246
regulation of cytokine productionGO:00018172660.246
Human Mouse
granulocyte migrationGO:0097530430.245
Mouse
negative regulation of immune system processGO:00026832090.245
regulation of cell adhesionGO:00301551540.245
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.243
purine ribonucleotide catabolic processGO:00091542080.242
keratinocyte migrationGO:005154630.242
cytokine mediated signaling pathwayGO:00192211150.241
hair follicle developmentGO:0001942850.240
striated muscle tissue developmentGO:00147062930.238
lens development in camera type eyeGO:0002088620.238
cellular response to dna damage stimulusGO:00069742070.237
ribonucleoside metabolic processGO:00091192450.237
mesenchymal cell differentiationGO:00487621070.236
Mouse
cell differentiation involved in kidney developmentGO:0061005330.236
stem cell maintenanceGO:00198271300.236
regulation of actin filament based processGO:0032970990.234
heart morphogenesisGO:00030071780.229
Mouse
positive regulation of dendrite developmentGO:1900006210.228
cellular response to hormone stimulusGO:00328701500.228
positive regulation of cell migration involved in sprouting angiogenesisGO:009005030.227
epithelial cell differentiation involved in mammary gland alveolus developmentGO:006103040.227
positive regulation of apoptotic processGO:00430652170.226
Mouse
ovarian follicle developmentGO:0001541400.226
lipid biosynthetic processGO:00086101790.226
regulation of glial cell differentiationGO:0045685410.225
mesonephric tubule morphogenesisGO:0072171630.225
t cell differentiationGO:00302171740.222
positive regulation of cell cycle processGO:0090068610.220
heterocycle catabolic processGO:00467002800.219
activation of mapkk activityGO:0000186150.218
response to organonitrogen compoundGO:00102432460.218
lymphocyte apoptotic processGO:0070227540.216
Mouse
cell cell signaling involved in metanephros developmentGO:007220420.216
dendritic spine organizationGO:0097061260.216
glycosyl compound metabolic processGO:19016572460.215
regulation of protein catabolic processGO:00421761080.215
Mouse
positive regulation of nucleotide biosynthetic processGO:0030810260.215
regulation of osteoblast proliferationGO:0033688150.214
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.213
regulation of fat cell differentiationGO:0045598810.212
positive regulation of map kinase activityGO:0043406840.212
Mouse
response to drugGO:0042493750.212
purine nucleoside triphosphate catabolic processGO:00091462030.212
leukocyte apoptotic processGO:0071887710.211
regulation of neural precursor cell proliferationGO:2000177700.210
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.208
negative regulation of t cell proliferationGO:0042130380.208
negative regulation of wnt signaling pathwayGO:0030178730.207
purine nucleotide catabolic processGO:00061952110.207
nephron epithelium developmentGO:0072009920.206
positive regulation of neuron differentiationGO:00456661410.206
innate immune responseGO:00450871570.206
Mouse
negative regulation of intracellular transportGO:0032387380.205
central nervous system morphogenesisGO:002155120.205
ureteric bud morphogenesisGO:0060675620.204
regulation of gliogenesisGO:0014013500.203
positive regulation of nucleotide metabolic processGO:00459811140.202
positive regulation of homeostatic processGO:0032846640.202
Mouse
regulation of notch signaling pathwayGO:0008593350.202
epidermal growth factor receptor signaling pathwayGO:0007173280.201
Human
purine containing compound catabolic processGO:00725232130.201
negative regulation of neuron apoptotic processGO:0043524920.200
Mouse
negative regulation of dendritic spine developmentGO:006100030.200
regulation of secretion by cellGO:19035302490.200
regulation of neuron apoptotic processGO:00435231220.199
Mouse
ensheathment of neuronsGO:0007272760.198
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.197
positive regulation of cell motilityGO:20001471160.196
Human Mouse
regulation of thymocyte apoptotic processGO:0070243140.195
Mouse
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.194
regulation of rac protein signal transductionGO:0035020190.194
calcium ion transportGO:00068161590.193
response to peptideGO:19016521360.193
regulation of smad protein import into nucleusGO:006039030.192
guanosine containing compound catabolic processGO:19010691440.192
hormone metabolic processGO:0042445860.192
regulation of cell morphogenesis involved in differentiationGO:00107691510.192
regulation of peptidase activityGO:0052547960.191
type i pneumocyte differentiationGO:006050970.189
prostate gland stromal morphogenesisGO:006074120.189
epithelial to mesenchymal transitionGO:0001837470.189
Mouse
cellular ion homeostasisGO:00068731650.187
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.186
pyramidal neuron migrationGO:002185210.184
gonad developmentGO:00084061410.184
sulfur compound metabolic processGO:00067901000.183
ribonucleotide biosynthetic processGO:0009260590.183
fat cell differentiationGO:00454441600.183
oocyte axis specificationGO:000730920.182
fibronectin dependent thymocyte migrationGO:007268110.181
Mouse
anatomical structure homeostasisGO:00602491450.181
Mouse
regulation of intracellular transportGO:00323861590.180
negative regulation of phosphorus metabolic processGO:00105631840.180
negative regulation of cellular amine metabolic processGO:003323910.179
cellular response to organonitrogen compoundGO:00714171450.179
purine ribonucleoside metabolic processGO:00461282410.178
4 hydroxyproline metabolic processGO:001947150.177
regulation of response to woundingGO:19030341890.177
Mouse
cellular response to oxidative stressGO:0034599760.176
organophosphate ester transportGO:0015748280.176
extracellular matrix dependent thymocyte migrationGO:007268010.176
Mouse
positive regulation of kinase activityGO:00336741550.175
Human Mouse
positive regulation of epithelial cell proliferationGO:0050679680.174
regulation of innate immune responseGO:0045088910.173
Mouse
muscle cell proliferationGO:0033002520.173
embryonic skeletal system developmentGO:00487061200.172
positive regulation of peptidase activityGO:0010952490.172
prevention of polyspermyGO:006046840.171
Mouse
notch signaling pathwayGO:0007219710.170
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.170
Mouse
male gamete generationGO:00482322850.169
adaptive immune responseGO:00022501550.169
regulation of carbohydrate metabolic processGO:0006109750.168
erythrocyte differentiationGO:0030218880.167
regulation of purine nucleotide biosynthetic processGO:1900371340.165
calcium ion homeostasisGO:00550741270.164
renal tubule morphogenesisGO:0061333720.163
cellular carbohydrate metabolic processGO:00442621190.162
positive regulation of purine nucleotide metabolic processGO:19005441140.161
negative regulation of cell developmentGO:00107211690.161
cytoplasmic transportGO:00164822340.160
negative regulation of cytokine productionGO:0001818840.160
Human
regulation of protein localizationGO:00328802310.159
rhythmic processGO:00485111740.159
cellular metal ion homeostasisGO:00068751510.159
cellular nitrogen compound catabolic processGO:00442702800.158
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.158
chromatin modificationGO:00165681870.158
regulation of secretionGO:00510462740.158
regulation of transmembrane transportGO:00347621280.157
response to metal ionGO:0010038470.157
regulation of heart contractionGO:0008016770.157
response to nutrient levelsGO:00316671090.157
cell proliferation in hindbrainGO:0021534100.156
regulation of cardiac muscle tissue developmentGO:0055024310.155
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.155
response to ionizing radiationGO:0010212420.154
response to oxidative stressGO:00069791230.154
dna metabolic processGO:00062593030.154
lytic vacuole organizationGO:0080171210.153
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.153
cellular response to organic cyclic compoundGO:0071407870.152
regulation of steroid hormone biosynthetic processGO:009003040.152
negative regulation of nervous system developmentGO:00519611560.151
inner ear receptor cell differentiationGO:0060113610.151
positive regulation of neuron projection developmentGO:0010976790.151
stress activated protein kinase signaling cascadeGO:0031098810.151
macromolecule catabolic processGO:00090572810.151
Mouse
activation of adenylate cyclase activityGO:000719040.150
regulation of cellular response to stressGO:00801351590.150
mitotic cell cycleGO:00002781950.150
Human
learning or memoryGO:00076111480.148
Mouse
regulation of wnt signaling pathwayGO:00301111230.148
cardiac muscle tissue developmentGO:00487381300.147
nitrogen compound transportGO:00717052710.146
lysosome organizationGO:0007040210.146
astrocyte differentiationGO:0048708430.145
stem cell proliferationGO:00720891170.145
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.145
granulocyte chemotaxisGO:0071621390.143
immune effector processGO:00022523210.143
leukocyte cell cell adhesionGO:0007159140.143
cell adhesion mediated by integrinGO:0033627180.142
Human
kidney morphogenesisGO:0060993830.142
negative regulation of dendritic spine morphogenesisGO:006100230.142
regulation of defense responseGO:00313472330.142
Mouse
skeletal muscle organ developmentGO:00605381630.142
cognitionGO:00508901490.141
Mouse
inner ear receptor cell developmentGO:0060119390.141
cardiac muscle tissue growthGO:0055017370.141
cell divisionGO:00513011200.141
bone developmentGO:00603481200.140
collagen metabolic processGO:0032963170.140
branching involved in ureteric bud morphogenesisGO:0001658560.140
cell differentiation involved in embryonic placenta developmentGO:0060706260.139
regulation of hormone levelsGO:00108172110.139
regulation of neurotransmitter levelsGO:0001505870.139
negative regulation of ras protein signal transductionGO:0046580180.138
ribonucleoside triphosphate catabolic processGO:00092031990.138
regulation of cell adhesion mediated by integrinGO:0033628130.138
negative regulation of type 2 immune responseGO:000282980.138
response to extracellular stimulusGO:00099911270.137
cation transmembrane transportGO:00986552660.137
skeletal muscle cell differentiationGO:0035914660.137
myeloid leukocyte migrationGO:0097529570.136
Mouse
neural fold elevation formationGO:002150210.136
retina morphogenesis in camera type eyeGO:0060042450.136
embryonic hemopoiesisGO:0035162230.136
positive regulation of stem cell proliferationGO:2000648590.136
regulation of epithelial cell proliferationGO:00506781410.135
regulation of nucleocytoplasmic transportGO:0046822730.135
i kappab kinase nf kappab signalingGO:0007249850.135
nuclear transportGO:00511691390.135
nephron morphogenesisGO:0072028690.135
cell maturationGO:00484691270.134
female gamete generationGO:0007292740.134
cardioblast migration to the midline involved in heart field formationGO:006097510.134
associative learningGO:0008306610.133
Mouse
glycoprotein metabolic processGO:00091001160.133
cellular response to fibroblast growth factor stimulusGO:0044344470.133
female sex differentiationGO:0046660840.133
canonical wnt signaling pathwayGO:00600701300.133
positive regulation of gtp catabolic processGO:0033126850.132
er nucleus signaling pathwayGO:0006984270.132
cell junction organizationGO:0034330770.132
cellular response to biotic stimulusGO:0071216920.130
regulation of nucleoside metabolic processGO:00091181300.130
developmental maturationGO:00217001930.130
positive regulation of cardioblast differentiationGO:005189130.129
regulation of protein kinase b signalingGO:0051896560.129
Mouse
regulation of cytoplasmic transportGO:19036491120.129
molting cycleGO:0042303900.129
g protein coupled receptor signaling pathwayGO:00071862430.127
Human
leukocyte chemotaxisGO:0030595690.127
Human Mouse
positive regulation of nf kappab transcription factor activityGO:0051092300.127
Mouse
regulation of neurotransmitter transportGO:0051588350.126
canonical wnt signaling pathway involved in heart developmentGO:006131630.125
positive regulation of protein phosphorylationGO:00019342420.125
Human Mouse
mesonephric epithelium developmentGO:0072163940.125
response to estrogenGO:0043627240.125

Adam17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.316
disease of cellular proliferationDOID:1456600.316
sensory system diseaseDOID:005015500.298
disease of anatomical entityDOID:700.298
eye and adnexa diseaseDOID:149200.298
nervous system diseaseDOID:86300.298
noonan syndromeDOID:349000.133