Mus musculus

0 known processes

Adam18

a disintegrin and metallopeptidase domain 18

(Aliases: Adam27,Tmdc3,tMDCIII,Dtgn3)

Adam18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatogenesisGO:00072832840.111
male gamete generationGO:00482322850.083
response to organonitrogen compoundGO:00102432460.066
locomotory behaviorGO:00076261950.066
carbohydrate metabolic processGO:00059752300.064
regulation of defense responseGO:00313472330.062
cellular ketone metabolic processGO:0042180840.061
asymmetric stem cell divisionGO:009872230.052
cellular amine metabolic processGO:0044106440.050
gland developmentGO:00487323300.049
amine metabolic processGO:0009308450.049
epithelial cell developmentGO:00020641590.047
cellular response to hormone stimulusGO:00328701500.047
cation transmembrane transportGO:00986552660.046
sensory perceptionGO:00076002450.046
peptidyl amino acid modificationGO:00181933360.046
single fertilizationGO:0007338820.043
regulation of cellular amino acid metabolic processGO:000652150.043
cell divisionGO:00513011200.042
cell type specific apoptotic processGO:00972852680.042
forebrain developmentGO:00309003020.042
leukocyte differentiationGO:00025213420.041
regulation of cellular ketone metabolic processGO:0010565660.041
positive regulation of cellular amine metabolic processGO:003324050.041
organic hydroxy compound metabolic processGO:19016152030.038
carbohydrate derivative biosynthetic processGO:19011371830.038
epidermis developmentGO:00085441870.037
regulation of cellular amine metabolic processGO:0033238200.037
homeostasis of number of cellsGO:00488722100.037
t cell activationGO:00421102890.036
cellular amino acid metabolic processGO:00065201030.036
response to light stimulusGO:00094161350.036
rhythmic processGO:00485111740.035
proteoglycan metabolic processGO:0006029380.034
ion transmembrane transportGO:00342203610.034
protein localization to organelleGO:00333651850.034
learningGO:0007612980.034
negative regulation of growthGO:0045926990.034
immune effector processGO:00022523210.034
stem cell differentiationGO:00488632680.034
cytokine productionGO:00018163190.033
cell adhesionGO:00071553290.033
multi multicellular organism processGO:00447061090.033
response to steroid hormoneGO:0048545560.033
lymphocyte differentiationGO:00300982420.032
synaptic transmissionGO:00072683290.032
proteoglycan biosynthetic processGO:0030166200.032
response to organic cyclic compoundGO:00140701980.032
negative regulation of cell cycleGO:00457861230.031
cation homeostasisGO:00550802120.031
nitrogen compound transportGO:00717052710.031
response to peptideGO:19016521360.031
regulation of cardiac muscle tissue growthGO:0055021260.031
cardiocyte differentiationGO:0035051870.031
generation of precursor metabolites and energyGO:00060911030.030
embryonic organ morphogenesisGO:00485622760.030
protein kinase b signalingGO:0043491740.030
actin cytoskeleton organizationGO:00300362200.030
oxidation reduction processGO:00551143420.030
monocarboxylic acid metabolic processGO:00327871910.029
negative regulation of cellular component organizationGO:00511291940.029
blood circulationGO:00080151950.029
exocytosisGO:00068871210.029
mapk cascadeGO:00001652810.029
endomembrane system organizationGO:00102561470.029
kidney developmentGO:00018222130.029
regulation of secretion by cellGO:19035302490.029
fertilizationGO:00095661270.028
positive regulation of protein phosphorylationGO:00019342420.028
regulation of apoptotic signaling pathwayGO:20012331970.028
regulation of circadian sleep wake cycle sleepGO:004518730.028
negative regulation of phosphorus metabolic processGO:00105631840.028
camera type eye developmentGO:00430102660.027
intracellular protein transportGO:00068862040.027
response to peptide hormoneGO:00434341270.027
small gtpase mediated signal transductionGO:0007264970.027
regulation of cellular component biogenesisGO:00440871810.027
transmembrane transportGO:00550854120.027
regulation of lymphocyte activationGO:00512492400.027
transmission of nerve impulseGO:0019226760.027
negative regulation of cellular protein metabolic processGO:00322692470.027
regulation of membrane potentialGO:00423911920.027
action potentialGO:0001508780.027
nucleotide metabolic processGO:00091173320.026
physiological cardiac muscle hypertrophyGO:000330130.026
response to radiationGO:00093141650.026
metal ion homeostasisGO:00550651890.026
muscle cell differentiationGO:00426922610.026
circadian rhythmGO:00076231140.025
regulation of protein transportGO:00512231630.025
urogenital system developmentGO:00016552610.025
protein modification by small protein conjugation or removalGO:00706472070.025
cell growthGO:00160491300.025
microtubule based processGO:00070172360.025
negative regulation of phosphate metabolic processGO:00459361840.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.025
cellular protein complex assemblyGO:00436231160.025
regulation of mapk cascadeGO:00434082480.025
inorganic cation transmembrane transportGO:00986622070.025
muscle system processGO:00030121410.025
glycoprotein biosynthetic processGO:0009101890.025
activation of immune responseGO:00022531380.025
nerve developmentGO:0021675670.024
telencephalon developmentGO:00215371860.024
cell fate commitmentGO:00451652100.024
positive regulation of protein modification processGO:00314012990.024
inorganic ion transmembrane transportGO:00986602340.024
macromolecule catabolic processGO:00090572810.024
regulation of organelle organizationGO:00330432890.024
lymphocyte mediated immunityGO:00024491390.023
respiratory tube developmentGO:00303231670.023
negative regulation of protein metabolic processGO:00512482820.023
regulation of cell cycle processGO:00105641600.023
cellular homeostasisGO:00197252400.023
regulation of cell activationGO:00508652890.023
meiotic nuclear divisionGO:00071261150.023
apoptotic signaling pathwayGO:00971903060.022
regulation of circadian sleep wake cycleGO:004274930.022
regulation of heart growthGO:0060420310.022
insulin receptor signaling pathwayGO:0008286490.022
protein catabolic processGO:00301632210.022
respiratory system developmentGO:00605411900.022
leukocyte mediated immunityGO:00024431740.022
response to testosteroneGO:003357430.022
organ growthGO:00352651170.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
positive regulation of lymphocyte activationGO:00512511400.022
cardiac muscle cell developmentGO:0055013390.022
immune response activating signal transductionGO:00027571160.022
positive regulation of cell developmentGO:00107202370.022
skin developmentGO:00435882200.022
single organism nuclear importGO:1902593950.021
regulation of organ growthGO:0046620610.021
negative regulation of molecular functionGO:00440922580.021
connective tissue developmentGO:00614481790.021
cellular response to organonitrogen compoundGO:00714171450.021
positive regulation of protein transportGO:0051222930.021
regulation of anatomical structure sizeGO:00900661780.021
germ cell developmentGO:00072811850.021
regulation of cytokine productionGO:00018172660.021
regulation of secretionGO:00510462740.021
cellular response to peptideGO:1901653920.021
regulation of carbohydrate metabolic processGO:0006109750.020
dna metabolic processGO:00062593030.020
sulfur compound metabolic processGO:00067901000.020
glial cell developmentGO:0021782540.020
protein ubiquitinationGO:00165671710.020
multicellular organism growthGO:00352641610.020
regulation of epithelial cell proliferationGO:00506781410.020
lymphocyte proliferationGO:00466511640.020
nucleobase containing small molecule metabolic processGO:00550863520.020
regulation of response to woundingGO:19030341890.020
nucleoside triphosphate metabolic processGO:00091412300.020
muscle cell developmentGO:00550011330.020
glial cell differentiationGO:00100011310.020
heart growthGO:0060419450.020
sodium ion transmembrane transportGO:0035725490.020
hematopoietic progenitor cell differentiationGO:00022441430.020
photoreceptor cell differentiationGO:0046530520.020
protein localization to nucleusGO:00345041210.020
cellular carbohydrate metabolic processGO:00442621190.019
b cell differentiationGO:0030183780.019
regulation of mitotic cell cycleGO:00073461260.019
leukocyte homeostasisGO:0001776790.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
endocytosisGO:00068971680.019
mitochondrion organizationGO:00070051340.019
nucleocytoplasmic transportGO:00069131390.019
cell maturationGO:00484691270.019
microtubule based movementGO:0007018840.019
neural precursor cell proliferationGO:00613511210.019
leukocyte proliferationGO:00706611720.019
ribose phosphate metabolic processGO:00196932910.019
purine ribonucleotide metabolic processGO:00091502900.019
cellular response to insulin stimulusGO:0032869780.019
modification dependent macromolecule catabolic processGO:00436321330.019
negative regulation of intracellular signal transductionGO:19025321670.019
regulation of cell cycleGO:00517262810.019
regulation of protein maturationGO:1903317960.019
positive regulation of kinase activityGO:00336741550.019
positive regulation of innate immune responseGO:0045089800.019
negative regulation of response to woundingGO:1903035770.019
regulation of cell migrationGO:00303342190.019
regulation of cell growthGO:0001558910.018
positive regulation of transferase activityGO:00513471670.018
neuron apoptotic processGO:00514021420.018
regionalizationGO:00030023370.018
asymmetric neuroblast divisionGO:005505910.018
regulation of blood circulationGO:1903522930.018
negative regulation of cell developmentGO:00107211690.018
multicellular organismal signalingGO:0035637910.018
cardiac muscle cell differentiationGO:0055007690.018
response to growth factorGO:00708481980.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
regulation of cardiac muscle tissue developmentGO:0055024310.018
negative regulation of cellular amine metabolic processGO:003323910.018
regulation of cellular carbohydrate metabolic processGO:0010675750.018
regulation of multi organism processGO:00439001110.018
regulation of cell projection organizationGO:00313442060.018
regulation of purine nucleotide metabolic processGO:19005421690.018
nucleoside phosphate metabolic processGO:00067533380.018
monosaccharide metabolic processGO:00059961060.018
glycoprotein metabolic processGO:00091001160.018
lung developmentGO:00303241640.017
b cell activationGO:00421131610.017
learning or memoryGO:00076111480.017
pallium developmentGO:00215431200.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
regulation of hormone levelsGO:00108172110.017
sodium ion transportGO:0006814730.017
cation transportGO:00068123990.017
male meiosisGO:0007140370.017
b cell mediated immunityGO:0019724710.017
protein maturationGO:00516041760.017
cellular response to extracellular stimulusGO:0031668810.017
olfactory learningGO:000835520.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
cellular ion homeostasisGO:00068731650.017
alcohol metabolic processGO:00060661160.017
establishment of blood nerve barrierGO:000806530.017
nuclear transportGO:00511691390.017
single organism cell adhesionGO:00986021560.017
microtubule cytoskeleton organizationGO:00002261570.017
regulation of systemic arterial blood pressureGO:0003073610.017
innate immune responseGO:00450871570.017
physiological muscle hypertrophyGO:000329830.017
skeletal system developmentGO:00015013560.017
cytoplasmic transportGO:00164822340.017
conditioned taste aversionGO:000166140.016
protein modification by small protein conjugationGO:00324461870.016
sensory perception of soundGO:0007605970.016
neuron neuron synaptic transmissionGO:0007270690.016
maintenance of locationGO:0051235890.016
peptide secretionGO:00027901140.016
cell growth involved in cardiac muscle cell developmentGO:006104930.016
regulation of innate immune responseGO:0045088910.016
multicellular organismal homeostasisGO:00488711640.016
renal system developmentGO:00720012250.016
meiotic cell cycle processGO:1903046770.016
regulation of protein kinase b signalingGO:0051896560.016
negative regulation of neuron deathGO:1901215980.016
purine nucleotide metabolic processGO:00061633020.016
lateral inhibitionGO:004633110.016
bmp signaling pathwayGO:0030509930.016
response to extracellular stimulusGO:00099911270.016
negative regulation of nervous system developmentGO:00519611560.016
cellular metal ion homeostasisGO:00068751510.016
negative regulation of organelle organizationGO:0010639900.016
oocyte constructionGO:000730820.016
oocyte axis specificationGO:000730920.016
negative regulation of cell proliferationGO:00082852960.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
t cell differentiationGO:00302171740.016
regulation of protein processingGO:0070613960.016
transforming growth factor beta receptor signaling pathwayGO:0007179710.016
cognitionGO:00508901490.015
purine nucleotide catabolic processGO:00061952110.015
regulation of ion transportGO:00432692150.015
ribonucleotide metabolic processGO:00092592910.015
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.015
regulation of cellular catabolic processGO:00313292420.015
establishment of protein localization to organelleGO:00725941180.015
cell cycle switchingGO:006018410.015
carbohydrate derivative catabolic processGO:19011362310.015
tube closureGO:0060606910.015
cellular lipid metabolic processGO:00442553230.015
ras protein signal transductionGO:0007265770.015
mitotic cell cycleGO:00002781950.015
cellular response to peptide hormone stimulusGO:0071375920.015
primary neural tube formationGO:0014020950.015
cardiac cell developmentGO:0055006410.015
membrane organizationGO:00610242450.015
sperm egg recognitionGO:0035036370.015
regulation of homeostatic processGO:00328441820.015
positive regulation of protein kinase b signalingGO:0051897320.015
cellular response to growth factor stimulusGO:00713631970.015
negative regulation of phosphorylationGO:00423261660.015
stem cell developmentGO:00488642190.015
immune response regulating signaling pathwayGO:00027641250.015
gliogenesisGO:00420631410.015
neuromuscular processGO:0050905990.015
visual behaviorGO:0007632450.014
mucopolysaccharide metabolic processGO:1903510250.014
regulation of proteolysisGO:00301621640.014
regulation of microtubule based processGO:0032886520.014
regulation of feeding behaviorGO:006025930.014
divalent inorganic cation homeostasisGO:00725071380.014
regulation of vesicle mediated transportGO:00606271390.014
androgen biosynthetic processGO:000670240.014
spermatid differentiationGO:00485151150.014
sensory organ morphogenesisGO:00905962420.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of leukocyte differentiationGO:19021051590.014
organonitrogen compound biosynthetic processGO:19015661920.014
extracellular structure organizationGO:00430621480.014
organelle localizationGO:00516401790.014
response to transforming growth factor betaGO:0071559880.014
adult behaviorGO:00305341350.014
organelle fissionGO:00482851700.014
inflammatory responseGO:00069542440.014
cellular chemical homeostasisGO:00550822150.014
hexose metabolic processGO:0019318980.014
nuclear divisionGO:00002801580.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
muscle tissue developmentGO:00605373080.014
spermatid developmentGO:00072861080.014
mesodermal cell migrationGO:000807840.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
circulatory system processGO:00030131970.014
regulation of protein localizationGO:00328802310.014
regulation of protein kinase activityGO:00458592320.013
smoothened signaling pathwayGO:00072241050.013
cellular response to lipidGO:00713961450.013
cellular component assembly involved in morphogenesisGO:00109271390.013
regulation of muscle tissue developmentGO:1901861970.013
protein targetingGO:00066051430.013
wnt signaling pathwayGO:00160551880.013
regulation of metal ion transportGO:00109591060.013
regulation of protein catabolic processGO:00421761080.013
pancreas developmentGO:0031016570.013
regulation of lymphocyte proliferationGO:00506701170.013
regulation of heart contractionGO:0008016770.013
sulfur compound biosynthetic processGO:0044272370.013
lipid biosynthetic processGO:00086101790.013
gonad developmentGO:00084061410.013
small molecule biosynthetic processGO:00442831320.013
mesonephric epithelium developmentGO:0072163940.013
ubiquitin dependent protein catabolic processGO:00065111290.013
myeloid leukocyte differentiationGO:00025731190.013
male sex differentiationGO:00466611090.013
posttranscriptional regulation of gene expressionGO:00106081550.013
cardiac chamber developmentGO:00032051080.013
carbohydrate biosynthetic processGO:0016051740.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
erk1 and erk2 cascadeGO:0070371770.013
muscle contractionGO:00069361010.013
protein oligomerizationGO:0051259670.013
ear developmentGO:00435832000.013
heterocycle catabolic processGO:00467002800.013
regulation of cell divisionGO:0051302760.013
regulation of muscle system processGO:0090257800.013
calcium ion homeostasisGO:00550741270.013
epithelial tube morphogenesisGO:00605623030.013
developmental cell growthGO:0048588840.013
modification dependent protein catabolic processGO:00199411330.012
his purkinje system developmentGO:000316440.012
adaptive immune responseGO:00022501550.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
protein importGO:00170381010.012
myeloid cell differentiationGO:00300992330.012
compound eye developmentGO:004874910.012
regulation of organ morphogenesisGO:20000271440.012
meiotic cell cycleGO:00513211220.012
fat cell differentiationGO:00454441600.012
regulation of establishment of protein localizationGO:00702011810.012
protein secretionGO:00093061110.012
steroid metabolic processGO:00082021190.012
ribonucleoside metabolic processGO:00091192450.012
regulation of ketone biosynthetic processGO:001056620.012
heart contractionGO:0060047930.012
glycerolipid metabolic processGO:00464861220.012
purine nucleoside catabolic processGO:00061522050.012
purine ribonucleoside metabolic processGO:00461282410.012
negative regulation of neuron apoptotic processGO:0043524920.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
heart morphogenesisGO:00030071780.012
regulation of cellular response to stressGO:00801351590.012
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.012
cellular protein catabolic processGO:00442571550.012
peptidyl serine phosphorylationGO:0018105740.012
hindbrain developmentGO:00309021280.012
digestive system developmentGO:00551232000.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
regulation of transferase activityGO:00513382630.012
cellular response to testosterone stimulusGO:007139410.012
development of primary sexual characteristicsGO:00451371430.012
immunoglobulin mediated immune responseGO:0016064690.012
striated muscle tissue developmentGO:00147062930.012
regulation of muscle contractionGO:0006937490.012
skeletal system morphogenesisGO:00487052030.012
negative regulation of mitotic cell cycleGO:0045930580.012
protein polymerizationGO:0051258570.012
regulation of blood pressureGO:0008217930.012
multi organism behaviorGO:0051705620.011
central nervous system neuron differentiationGO:00219531620.011
response to insulinGO:00328681000.011
striated muscle cell developmentGO:00550021250.011
response to decreased oxygen levelsGO:0036293590.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
regulation of protein serine threonine kinase activityGO:00719001570.011
regulation of bindingGO:00510981110.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
columnar cuboidal epithelial cell developmentGO:0002066290.011
epithelial tube formationGO:00721751300.011
nucleotide catabolic processGO:00091662170.011
myeloid cell homeostasisGO:00022621140.011
axonogenesisGO:00074092740.011
regulation of hydrolase activityGO:00513362460.011
germ line stem cell divisionGO:004207820.011
purine nucleoside metabolic processGO:00422782410.011
ossificationGO:00015032160.011
tumor necrosis factor ligand superfamily member 11 productionGO:007253510.011
mesonephros developmentGO:0001823970.011
cardiac muscle tissue developmentGO:00487381300.011
regulation of inflammatory responseGO:00507271470.011
epithelial cell proliferationGO:00506731740.011
testosterone biosynthetic processGO:006137020.011
reactive oxygen species metabolic processGO:0072593840.011
regulation of cardioblast differentiationGO:005189030.011
regulation of protein complex assemblyGO:0043254830.011
endocrine system developmentGO:0035270980.011
regulation of leukocyte proliferationGO:00706631210.011
regulation of neuron apoptotic processGO:00435231220.011
bundle of his developmentGO:000316640.011
stem cell proliferationGO:00720891170.011
regulation of cellular component sizeGO:00325351210.011
mitotic cell cycle processGO:19030471590.011
negative regulation of immune system processGO:00026832090.011
multicellular organismal response to stressGO:0033555620.011
actin mediated cell contractionGO:0070252150.011
positive regulation of cell activationGO:00508671580.011
tube formationGO:00351481400.011
meiosis iGO:0007127600.011
protein localization to membraneGO:00726571080.011
female gamete generationGO:0007292740.011
chromosome organization involved in meiosisGO:0070192390.011
regulation of intracellular transportGO:00323861590.011
inner ear receptor cell differentiationGO:0060113610.011
male genitalia morphogenesisGO:004880840.011
nucleoside metabolic processGO:00091162460.011
ribonucleotide catabolic processGO:00092612080.011
morphogenesis of embryonic epitheliumGO:00163311590.011
purine containing compound metabolic processGO:00725213110.011
spinal cord oligodendrocyte cell differentiationGO:002152930.011
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.011
canonical wnt signaling pathwayGO:00600701300.011
pole plasm assemblyGO:000731520.011
negative regulation of defense responseGO:0031348770.011
regulation of neurotransmitter levelsGO:0001505870.011
establishment or maintenance of cell polarityGO:0007163860.010
protein import into nucleusGO:0006606950.010
response to monosaccharideGO:0034284670.010
activation of mapk activity involved in innate immune responseGO:003541920.010
oocyte anterior posterior axis specificationGO:000731420.010
ribonucleoside triphosphate catabolic processGO:00092031990.010
dna recombinationGO:0006310920.010
regulation of t cell activationGO:00508631700.010
adult locomotory behaviorGO:0008344910.010
female sex differentiationGO:0046660840.010
positive regulation of nervous system developmentGO:00519622210.010
visual learningGO:0008542440.010
regulation of neuron differentiationGO:00456642810.010
response to lipopolysaccharideGO:00324961280.010
neuroblast fate commitmentGO:001401710.010
mesoderm developmentGO:00074981000.010
regulation of sodium ion transportGO:0002028290.010
neuron deathGO:00709971540.010
cardiac muscle tissue growthGO:0055017370.010
regulation of ion transmembrane transportGO:00347651190.010
regulation of b cell activationGO:0050864810.010
proteolysis involved in cellular protein catabolic processGO:00516031470.010
aromatic compound catabolic processGO:00194392860.010
response to fibroblast growth factorGO:0071774470.010
activation of innate immune responseGO:0002218560.010
regulation of neuron deathGO:19012141340.010
mesenchyme developmentGO:00604851520.010
muscle cell proliferationGO:0033002520.010
regulation of cytoplasmic transportGO:19036491120.010
schwann cell developmentGO:0014044220.010

Adam18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
musculoskeletal system diseaseDOID:1700.013
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.013
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012