Mus musculus

16 known processes

Adam1a

a disintegrin and metallopeptidase domain 1a

(Aliases: Ftna,Adam1)

Adam1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308450.098
t helper 2 cell cytokine productionGO:003574540.087
natural killer cell activation involved in immune responseGO:0002323100.084
interleukin 5 secretionGO:007260320.083
transmembrane transportGO:00550854120.072
ion transmembrane transportGO:00342203610.071
regulation of membrane potentialGO:00423911920.070
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.069
divalent inorganic cation homeostasisGO:00725071380.061
cellular ketone metabolic processGO:0042180840.061
positive regulation of protein phosphorylationGO:00019342420.059
Mouse
cellular amino acid metabolic processGO:00065201030.058
g protein coupled receptor signaling pathwayGO:00071862430.057
regulation of cellular catabolic processGO:00313292420.056
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.056
cation transportGO:00068123990.051
action potentialGO:0001508780.050
Mouse
multicellular organism growthGO:00352641610.050
endocytosisGO:00068971680.047
regulation of cellular amine metabolic processGO:0033238200.046
circulatory system processGO:00030131970.044
regulation of cellular amino acid metabolic processGO:000652150.043
synaptic transmissionGO:00072683290.042
transmission of nerve impulseGO:0019226760.041
Mouse
sensory perceptionGO:00076002450.040
response to radiationGO:00093141650.039
Mouse
negative regulation of t cell cytokine productionGO:000272510.039
gliogenesisGO:00420631410.038
Mouse
purine ribonucleotide metabolic processGO:00091502900.037
regulation of ion transmembrane transportGO:00347651190.037
cellular calcium ion homeostasisGO:00068741190.037
regulation of lymphocyte mediated immunityGO:0002706840.037
positive regulation of apoptotic signaling pathwayGO:2001235950.035
calcium ion homeostasisGO:00550741270.035
cd4 positive alpha beta t cell cytokine productionGO:003574340.035
cation transmembrane transportGO:00986552660.034
carbohydrate derivative biosynthetic processGO:19011371830.034
nucleoside metabolic processGO:00091162460.033
adult behaviorGO:00305341350.033
Mouse
rhodopsin mediated signaling pathwayGO:001605640.033
cellular homeostasisGO:00197252400.032
negative regulation of protein metabolic processGO:00512482820.032
cellular chemical homeostasisGO:00550822150.031
positive regulation of protein modification processGO:00314012990.031
Mouse
regulation of cellular ketone metabolic processGO:0010565660.031
cellular divalent inorganic cation homeostasisGO:00725031270.030
nucleobase containing small molecule metabolic processGO:00550863520.030
positive regulation of apoptotic processGO:00430652170.030
Mouse
regulation of protein kinase activityGO:00458592320.029
Mouse
regulation of interleukin 13 secretionGO:200066520.028
regulation of purine nucleotide metabolic processGO:19005421690.028
cellular ion homeostasisGO:00068731650.028
positive regulation of cellular amine metabolic processGO:003324050.028
sequestering of calcium ionGO:0051208180.028
developmental maturationGO:00217001930.028
nucleoside phosphate metabolic processGO:00067533380.027
purine nucleotide metabolic processGO:00061633020.027
glycosyl compound metabolic processGO:19016572460.027
cytosolic calcium ion homeostasisGO:0051480700.027
b cell activationGO:00421131610.027
Mouse
monocarboxylic acid metabolic processGO:00327871910.027
blood vessel morphogenesisGO:00485142850.027
Mouse
regulation of neuron deathGO:19012141340.026
Mouse
secondary alcohol metabolic processGO:190265230.026
purine nucleoside metabolic processGO:00422782410.025
positive regulation of transferase activityGO:00513471670.025
Mouse
regulation of organelle organizationGO:00330432890.024
cellular metal ion homeostasisGO:00068751510.024
positive regulation of kinase activityGO:00336741550.024
Mouse
negative regulation of immune system processGO:00026832090.024
regulation of t helper 2 cell cytokine productionGO:200055130.024
ribonucleotide metabolic processGO:00092592910.024
activation of nf kappab inducing kinase activityGO:000725040.024
fatty acid metabolic processGO:00066311210.024
cellular amine metabolic processGO:0044106440.023
regulation of leukocyte mediated immunityGO:00027031040.022
reactive oxygen species metabolic processGO:0072593840.022
positive regulation of secretionGO:00510471300.022
nucleotide metabolic processGO:00091173320.022
response to organonitrogen compoundGO:00102432460.021
fertilizationGO:00095661270.021
regulation of neurotransmitter transportGO:0051588350.021
glucose homeostasisGO:00425931280.021
protein localization to organelleGO:00333651850.021
response to painGO:0048265260.021
regulation of neuron apoptotic processGO:00435231220.021
Mouse
leukocyte differentiationGO:00025213420.020
Mouse
renal system developmentGO:00720012250.020
cytokine productionGO:00018163190.020
Mouse
blood circulationGO:00080151950.020
regulation of kinase activityGO:00435492490.019
Mouse
positive regulation of protein serine threonine kinase activityGO:00719021060.019
Mouse
cellular response to cytokine stimulusGO:00713451890.019
regulation of complement activation classical pathwayGO:003045010.019
organic anion transportGO:00157111370.019
entry into other organism involved in symbiotic interactionGO:0051828150.019
response to acid chemicalGO:00011011110.019
membrane organizationGO:00610242450.019
negative regulation of complement activationGO:004591630.019
maintenance of locationGO:0051235890.019
neuron apoptotic processGO:00514021420.019
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.019
Mouse
regulation of hydrolase activityGO:00513362460.018
apoptotic signaling pathwayGO:00971903060.018
inorganic ion transmembrane transportGO:00986602340.018
peptide transportGO:00158331330.018
regulation of protein localizationGO:00328802310.018
b cell differentiationGO:0030183780.018
Mouse
lung developmentGO:00303241640.018
spermatid differentiationGO:00485151150.018
viral processGO:0016032410.018
regulation of transferase activityGO:00513382630.018
Mouse
camera type eye developmentGO:00430102660.018
positive regulation of cell deathGO:00109422240.017
Mouse
negative regulation of interleukin 5 productionGO:003271440.017
regulation of nucleotide metabolic processGO:00061401690.017
purine containing compound catabolic processGO:00725232130.017
response to light stimulusGO:00094161350.017
Mouse
organonitrogen compound catabolic processGO:19015652640.017
lymphocyte mediated immunityGO:00024491390.017
neuronal action potentialGO:0019228540.017
Mouse
cellular lipid metabolic processGO:00442553230.017
regulation of secretion by cellGO:19035302490.016
cation homeostasisGO:00550802120.016
forebrain developmentGO:00309003020.016
multicellular organismal signalingGO:0035637910.016
Mouse
anion transportGO:00068201770.016
sequestering of metal ionGO:0051238190.016
regulation of monocyte extravasationGO:200043720.016
muscle cell differentiationGO:00426922610.016
neuron deathGO:00709971540.016
Mouse
natural killer cell activationGO:0030101440.016
urogenital system developmentGO:00016552610.016
divalent inorganic cation transportGO:00725111780.016
fat cell differentiationGO:00454441600.016
negative regulation of immune effector processGO:0002698550.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
production of molecular mediator of immune responseGO:00024401030.016
nucleoside phosphate catabolic processGO:19012922220.015
positive regulation of mapk cascadeGO:00434101700.015
Mouse
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.015
lymphocyte activation involved in immune responseGO:0002285930.015
positive regulation of cell developmentGO:00107202370.015
establishment of protein localization to organelleGO:00725941180.015
negative regulation of interleukin 13 productionGO:003269620.015
regulation of cellular response to stressGO:00801351590.015
metal ion homeostasisGO:00550651890.015
regulation of hormone levelsGO:00108172110.015
ribonucleoside metabolic processGO:00091192450.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
male gamete generationGO:00482322850.015
heterocycle catabolic processGO:00467002800.015
cell activation involved in immune responseGO:00022631260.015
organic cyclic compound catabolic processGO:19013612950.014
multicellular organismal response to stressGO:0033555620.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
organonitrogen compound biosynthetic processGO:19015661920.014
regulation of neurotransmitter secretionGO:0046928290.014
regulation of postsynaptic membrane potentialGO:0060078480.014
cellular nitrogen compound catabolic processGO:00442702800.014
regulation of apoptotic signaling pathwayGO:20012331970.014
response to drugGO:0042493750.014
Mouse
cellular response to dna damage stimulusGO:00069742070.014
respiratory tube developmentGO:00303231670.014
negative regulation of inclusion body assemblyGO:009008410.014
lymphocyte differentiationGO:00300982420.014
Mouse
aromatic compound catabolic processGO:00194392860.014
regulation of response to woundingGO:19030341890.014
Mouse
retina homeostasisGO:0001895230.014
regulation of saliva secretionGO:004687720.014
glycoprotein metabolic processGO:00091001160.014
receptor mediated endocytosisGO:0006898510.014
dna metabolic processGO:00062593030.014
cell type specific apoptotic processGO:00972852680.014
Mouse
negative regulation of protein activation cascadeGO:200025830.014
detection of chemical stimulus involved in sensory perception of smellGO:005091140.014
digestive system developmentGO:00551232000.014
ribose phosphate metabolic processGO:00196932910.014
purine nucleoside catabolic processGO:00061522050.014
interleukin 13 secretionGO:007261120.014
carbohydrate metabolic processGO:00059752300.013
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of reproductive processGO:2000241660.013
Mouse
entry into hostGO:0044409150.013
mrna metabolic processGO:0016071840.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
purine containing compound metabolic processGO:00725213110.013
dna repairGO:00062811070.013
prevention of polyspermyGO:006046840.013
Mouse
engulfment of apoptotic cellGO:004365230.013
glycoprotein biosynthetic processGO:0009101890.013
regulation of proteolysisGO:00301621640.013
Mouse
regulation of interleukin 5 secretionGO:200066220.013
positive regulation of programmed cell deathGO:00430682180.013
Mouse
positive regulation of neuron deathGO:1901216280.013
jnk cascadeGO:0007254720.013
ras protein signal transductionGO:0007265770.013
digestive tract developmentGO:00485651900.013
negative regulation of protein phosphorylationGO:00019331260.013
entry into cell of other organism involved in symbiotic interactionGO:0051806150.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
positive regulation of thymocyte migrationGO:200041220.013
Mouse
striated muscle tissue developmentGO:00147062930.013
peptide hormone secretionGO:00300721090.012
respiratory gaseous exchangeGO:0007585430.012
positive regulation of homeostatic processGO:0032846640.012
Mouse
response to cholesterolGO:007072340.012
circadian regulation of gene expressionGO:0032922480.012
second messenger mediated signalingGO:0019932730.012
regulation of mapk cascadeGO:00434082480.012
Mouse
actin cytoskeleton organizationGO:00300362200.012
acetate ester transportGO:190137420.012
rho protein signal transductionGO:0007266320.012
regulation of neurotransmitter levelsGO:0001505870.012
intracellular protein transportGO:00068862040.012
regulation of blood pressureGO:0008217930.012
directional locomotionGO:003305830.012
glycosyl compound catabolic processGO:19016582060.012
purine ribonucleoside metabolic processGO:00461282410.012
hematopoietic progenitor cell differentiationGO:00022441430.012
nucleocytoplasmic transportGO:00069131390.012
carbohydrate homeostasisGO:00335001280.012
inorganic cation transmembrane transportGO:00986622070.012
negative regulation of cell motilityGO:2000146610.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
t cell activation involved in immune responseGO:0002286430.012
protein modification by small protein conjugation or removalGO:00706472070.012
stress activated protein kinase signaling cascadeGO:0031098810.012
positive regulation of protein kinase activityGO:00458601440.012
Mouse
protein catabolic processGO:00301632210.012
Mouse
glial cell differentiationGO:00100011310.012
Mouse
proteolysis involved in cellular protein catabolic processGO:00516031470.012
small gtpase mediated signal transductionGO:0007264970.012
protein maturationGO:00516041760.012
protein targetingGO:00066051430.011
regulation of fertilizationGO:008015440.011
cognitionGO:00508901490.011
Mouse
homeostasis of number of cellsGO:00488722100.011
Mouse
interspecies interaction between organismsGO:0044419830.011
regulation of leukocyte differentiationGO:19021051590.011
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.011
cytoplasmic transportGO:00164822340.011
neuromuscular processGO:0050905990.011
regulation of t cell activationGO:00508631700.011
Mouse
positive regulation of secretion by cellGO:19035321140.011
renin angiotensin regulation of aldosterone productionGO:000201830.011
photoreceptor cell differentiationGO:0046530520.011
entry into host cellGO:0030260150.011
viral life cycleGO:0019058360.011
cofactor metabolic processGO:0051186800.011
spermatid developmentGO:00072861080.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
cellular response to light stimulusGO:0071482190.011
developmental growth involved in morphogenesisGO:00605601380.011
activation of immune responseGO:00022531380.011
Mouse
macromolecule catabolic processGO:00090572810.011
Mouse
apoptotic mitochondrial changesGO:0008637480.011
carboxylic acid transportGO:00469421000.011
positive regulation of nucleoside metabolic processGO:0045979910.011
peptidyl amino acid modificationGO:00181933360.011
nucleotide catabolic processGO:00091662170.011
pma inducible membrane protein ectodomain proteolysisGO:005108810.011
Mouse
sulfur compound metabolic processGO:00067901000.011
multicellular organismal homeostasisGO:00488711640.011
Mouse
drug metabolic processGO:001714440.010
aldosterone metabolic processGO:003234120.010
calcium ion transportGO:00068161590.010
regulation of secretionGO:00510462740.010
positive regulation of cytosolic calcium ion concentrationGO:0007204650.010
nucleoside triphosphate metabolic processGO:00091412300.010
organophosphate catabolic processGO:00464342320.010
regulation of cell migrationGO:00303342190.010
Mouse
rhythmic processGO:00485111740.010
hexose transportGO:0008645560.010
stem cell developmentGO:00488642190.010
Mouse
photoreceptor cell developmentGO:0042461400.010
nucleoside catabolic processGO:00091642060.010
regulation of nucleotide catabolic processGO:00308111220.010
regulation of production of molecular mediator of immune responseGO:0002700650.010
regulation of feeding behaviorGO:006025930.010

Adam1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.105
retinal diseaseDOID:567900.105
eye and adnexa diseaseDOID:149200.105
nervous system diseaseDOID:86300.105
eye diseaseDOID:561400.105
disease of anatomical entityDOID:700.105
central nervous system diseaseDOID:33100.039
retinal degenerationDOID:846600.034
retinitis pigmentosaDOID:1058400.025
neurodegenerative diseaseDOID:128900.021
electroclinical syndromeDOID:005070100.014
epilepsy syndromeDOID:182600.014
brain diseaseDOID:93600.014
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012
disease by infectious agentDOID:005011700.012