Mus musculus

19 known processes

Pnpla6

patatin-like phospholipase domain containing 6

(Aliases: Nte,AI661849,MSws)

Pnpla6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.133
muscle cell developmentGO:00550011330.107
cellular nitrogen compound catabolic processGO:00442702800.106
transmembrane transportGO:00550854120.106
intracellular protein transportGO:00068862040.101
sa node cell action potentialGO:008601540.100
purine nucleotide catabolic processGO:00061952110.089
ras protein signal transductionGO:0007265770.085
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.084
muscle cell differentiationGO:00426922610.081
purine nucleotide metabolic processGO:00061633020.081
nucleotide catabolic processGO:00091662170.080
embryonic epithelial tube formationGO:00018381300.079
ventricular cardiac muscle cell action potentialGO:008600540.075
cation transmembrane transportGO:00986552660.075
glycosyl compound catabolic processGO:19016582060.075
regulation of cellular response to stressGO:00801351590.074
neural tube developmentGO:00219151600.073
neural tube formationGO:00018411080.071
ribose phosphate metabolic processGO:00196932910.071
epithelial tube formationGO:00721751300.071
nucleoside phosphate metabolic processGO:00067533380.071
tube formationGO:00351481400.069
organic cyclic compound catabolic processGO:19013612950.069
heterocycle catabolic processGO:00467002800.069
purine nucleoside triphosphate catabolic processGO:00091462030.069
amine metabolic processGO:0009308450.066
Fly
inorganic cation transmembrane transportGO:00986622070.066
morphogenesis of embryonic epitheliumGO:00163311590.066
glycosyl compound metabolic processGO:19016572460.066
nucleoside metabolic processGO:00091162460.065
small gtpase mediated signal transductionGO:0007264970.065
nucleoside triphosphate catabolic processGO:00091432050.063
posttranscriptional regulation of gene expressionGO:00106081550.063
regulation of membrane potentialGO:00423911920.061
divalent inorganic cation transportGO:00725111780.060
purine ribonucleoside catabolic processGO:00461302050.060
metal ion homeostasisGO:00550651890.058
nucleotide metabolic processGO:00091173320.058
ribonucleoside metabolic processGO:00091192450.057
cell type specific apoptotic processGO:00972852680.057
Fly
purine ribonucleoside metabolic processGO:00461282410.056
skin developmentGO:00435882200.056
inorganic ion transmembrane transportGO:00986602340.055
purine nucleoside triphosphate metabolic processGO:00091442260.055
sa node cell to atrial cardiac muscle cell signallingGO:008601840.054
nucleobase containing small molecule metabolic processGO:00550863520.053
membrane organizationGO:00610242450.053
Fly
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.051
purine nucleoside metabolic processGO:00422782410.051
ribonucleoside triphosphate catabolic processGO:00092031990.051
action potentialGO:0001508780.050
cellular chemical homeostasisGO:00550822150.050
positive regulation of jnk cascadeGO:0046330460.050
sequestering of calcium ionGO:0051208180.050
actin cytoskeleton organizationGO:00300362200.049
purine ribonucleoside triphosphate catabolic processGO:00092071990.048
nucleoside phosphate catabolic processGO:19012922220.048
nucleoside catabolic processGO:00091642060.048
ribonucleotide metabolic processGO:00092592910.048
ribonucleotide catabolic processGO:00092612080.047
purine ribonucleotide catabolic processGO:00091542080.047
negative regulation of organ growthGO:0046621170.047
placenta developmentGO:00018901400.046
sequestering of metal ionGO:0051238190.046
regulation of transmembrane transportGO:00347621280.045
purine ribonucleoside triphosphate metabolic processGO:00092052200.045
morphogenesis of a branching epitheliumGO:00611381930.044
iron ion homeostasisGO:0055072360.044
positive regulation of mapk cascadeGO:00434101700.043
ribonucleoside catabolic processGO:00424542060.043
cytoplasmic transportGO:00164822340.043
purine containing compound catabolic processGO:00725232130.043
jnk cascadeGO:0007254720.043
divalent metal ion transportGO:00708381720.043
cellular homeostasisGO:00197252400.043
regulation of stress activated mapk cascadeGO:0032872690.042
purine nucleoside catabolic processGO:00061522050.042
organonitrogen compound biosynthetic processGO:19015661920.042
regulation of mapk cascadeGO:00434082480.042
positive regulation of stress activated mapk cascadeGO:0032874480.042
endomembrane system organizationGO:00102561470.041
ribonucleoside triphosphate metabolic processGO:00091992200.041
negative regulation of growthGO:0045926990.041
nucleoside triphosphate metabolic processGO:00091412300.041
negative regulation of cell proliferationGO:00082852960.040
positive regulation of programmed cell deathGO:00430682180.040
keratinocyte differentiationGO:0030216480.040
morphogenesis of a branching structureGO:00017632030.040
axonogenesisGO:00074092740.040
organonitrogen compound catabolic processGO:19015652640.040
purine ribonucleotide metabolic processGO:00091502900.039
guanosine containing compound catabolic processGO:19010691440.039
regulation of purine nucleotide catabolic processGO:00331211220.039
guanosine containing compound metabolic processGO:19010681440.039
canonical wnt signaling pathwayGO:00600701300.038
neuronal action potentialGO:0019228540.038
purine containing compound metabolic processGO:00725213110.038
wnt signaling pathwayGO:00160551880.038
regulation of ion transmembrane transportGO:00347651190.038
carbohydrate derivative catabolic processGO:19011362310.037
maintenance of locationGO:0051235890.037
extrinsic apoptotic signaling pathwayGO:00971911260.037
gtp catabolic processGO:00061841430.037
actin filament based movementGO:0030048230.036
regulation of cellular catabolic processGO:00313292420.036
negative regulation of wnt signaling pathwayGO:0030178730.036
cardiac muscle cell contractionGO:008600370.036
cofactor metabolic processGO:0051186800.036
regulation of protein kinase activityGO:00458592320.036
regulation of cellular amine metabolic processGO:0033238200.036
cofactor biosynthetic processGO:0051188410.036
potassium ion transmembrane transportGO:0071805430.036
regulation of ion transportGO:00432692150.036
apoptotic signaling pathwayGO:00971903060.035
regulation of jnk cascadeGO:0046328620.035
cellular ion homeostasisGO:00068731650.035
calcium ion transmembrane transportGO:0070588850.035
epithelial tube morphogenesisGO:00605623030.034
aromatic compound catabolic processGO:00194392860.034
cation homeostasisGO:00550802120.034
transition metal ion homeostasisGO:0055076540.034
positive regulation of bindingGO:0051099490.034
regulation of protein stabilityGO:0031647520.034
positive regulation of gtpase activityGO:0043547850.033
cellular amino acid metabolic processGO:00065201030.033
positive regulation of apoptotic signaling pathwayGO:2001235950.033
regulation of nucleoside metabolic processGO:00091181300.033
fat cell differentiationGO:00454441600.033
actin mediated cell contractionGO:0070252150.033
regulation of purine nucleotide metabolic processGO:19005421690.033
protein localization to organelleGO:00333651850.033
regulation of bindingGO:00510981110.032
cellular potassium ion transportGO:0071804430.032
branching morphogenesis of an epithelial tubeGO:00487541590.032
embryonic placenta developmentGO:0001892980.032
transmission of nerve impulseGO:0019226760.031
epidermis developmentGO:00085441870.031
calcium ion transportGO:00068161590.031
positive regulation of apoptotic processGO:00430652170.031
mapk cascadeGO:00001652810.030
camera type eye developmentGO:00430102660.030
regulation of nucleotide catabolic processGO:00308111220.030
divalent inorganic cation homeostasisGO:00725071380.029
gtp metabolic processGO:00460391440.029
rho protein signal transductionGO:0007266320.029
regulation of homeostatic processGO:00328441820.029
regulation of ras protein signal transductionGO:00465781140.029
positive regulation of protein modification processGO:00314012990.028
cellular amine metabolic processGO:0044106440.028
Fly
chemotaxisGO:00069352470.028
regulation of cellular amino acid metabolic processGO:000652150.028
regulation of protein kinase b signalingGO:0051896560.028
regulation of protein bindingGO:0043393600.028
organophosphate catabolic processGO:00464342320.028
hepatocyte apoptotic processGO:0097284110.028
response to organonitrogen compoundGO:00102432460.028
synapse organizationGO:00508081250.028
endocytosisGO:00068971680.028
regulation of apoptotic signaling pathwayGO:20012331970.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
calcium ion homeostasisGO:00550741270.027
stress activated mapk cascadeGO:0051403800.027
regulation of cell cycleGO:00517262810.027
multicellular organismal signalingGO:0035637910.027
regulation of cellular ketone metabolic processGO:0010565660.027
cellular ketone metabolic processGO:0042180840.027
stress activated protein kinase signaling cascadeGO:0031098810.026
second messenger mediated signalingGO:0019932730.026
regulation of transporter activityGO:0032409570.026
positive regulation of hydrolase activityGO:00513451480.026
regulation of hydrolase activityGO:00513362460.026
blood vessel morphogenesisGO:00485142850.025
protein autophosphorylationGO:0046777610.025
regionalizationGO:00030023370.025
regulation of cell motilityGO:20001452360.025
positive regulation of purine nucleotide catabolic processGO:0033123880.025
organelle localizationGO:00516401790.025
striated muscle cell developmentGO:00550021250.025
positive regulation of protein phosphorylationGO:00019342420.025
protein kinase b signalingGO:0043491740.024
positive regulation of protein kinase b signalingGO:0051897320.024
response to growth factorGO:00708481980.024
regulation of wnt signaling pathwayGO:00301111230.024
regulation of ion transmembrane transporter activityGO:0032412540.023
plasma membrane organizationGO:0007009900.023
muscle fiber developmentGO:0048747760.023
protein localization to nucleusGO:00345041210.023
regulation of fat cell differentiationGO:0045598810.023
positive regulation of cell deathGO:00109422240.023
protein targetingGO:00066051430.023
positive regulation of potassium ion transportGO:004326830.023
protein localization to membraneGO:00726571080.023
porphyrin containing compound metabolic processGO:0006778220.023
microtubule based processGO:00070172360.023
regulation of ras gtpase activityGO:0032318880.023
release of sequestered calcium ion into cytosolGO:0051209420.022
synaptic transmissionGO:00072683290.022
positive regulation of nucleotide metabolic processGO:00459811140.022
anion transportGO:00068201770.022
positive regulation of nucleotide catabolic processGO:0030813880.022
positive regulation of protein bindingGO:0032092290.022
alcohol metabolic processGO:00060661160.022
Fly
regulation of calcium ion transport into cytosolGO:0010522310.022
positive regulation of nucleoside metabolic processGO:0045979910.022
regulation of nucleotide metabolic processGO:00061401690.022
cation transportGO:00068123990.022
g protein coupled receptor signaling pathwayGO:00071862430.022
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.021
negative regulation of molecular functionGO:00440922580.021
cellular metal ion homeostasisGO:00068751510.021
regulation of actin filament based processGO:0032970990.021
cellular divalent inorganic cation homeostasisGO:00725031270.021
muscle contractionGO:00069361010.021
regulation of canonical wnt signaling pathwayGO:0060828820.020
regulation of cell migrationGO:00303342190.020
cellular macromolecule catabolic processGO:00442652060.020
regulation of gtp catabolic processGO:00331241130.019
regulation of calcium ion transportGO:0051924690.019
cardiac septum developmentGO:0003279590.019
carbohydrate derivative biosynthetic processGO:19011371830.019
protein catabolic processGO:00301632210.019
positive regulation of gtp catabolic processGO:0033126850.019
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.019
organ growthGO:00352651170.019
regulation of neuron differentiationGO:00456642810.019
regulation of cell projection organizationGO:00313442060.019
myeloid cell differentiationGO:00300992330.019
tetrapyrrole metabolic processGO:0033013220.019
microtubule cytoskeleton organizationGO:00002261570.018
mitotic cell cycleGO:00002781950.018
protein modification by small protein conjugationGO:00324461870.018
positive regulation of cellular amine metabolic processGO:003324050.018
homeostasis of number of cellsGO:00488722100.018
regulation of reactive oxygen species biosynthetic processGO:190342620.018
multicellular organismal homeostasisGO:00488711640.018
positive regulation of cellular catabolic processGO:00313311480.018
peptidyl serine phosphorylationGO:0018105740.018
limb developmentGO:00601731660.018
positive regulation of kinase activityGO:00336741550.018
calcium ion transport into cytosolGO:0060402480.017
lateral inhibitionGO:004633110.017
regulation of system processGO:00440572000.017
reactive oxygen species biosynthetic processGO:190340980.017
circulatory system processGO:00030131970.017
retrograde transport endosome to golgiGO:004214720.017
positive regulation of ion transportGO:0043270650.017
negative regulation of canonical wnt signaling pathwayGO:0090090510.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
regulation of organ growthGO:0046620610.017
protein ubiquitinationGO:00165671710.017
reactive oxygen species metabolic processGO:0072593840.017
protein localization to plasma membraneGO:0072659570.017
immune effector processGO:00022523210.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
establishment or maintenance of cytoskeleton polarityGO:003095220.017
macromolecule catabolic processGO:00090572810.016
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.016
nitrogen compound transportGO:00717052710.016
regulation of transferase activityGO:00513382630.016
peptidyl amino acid modificationGO:00181933360.016
regulation of protein localizationGO:00328802310.016
cardiac muscle contractionGO:0060048320.016
regulation of metal ion transportGO:00109591060.016
peptidyl serine modificationGO:0018209830.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
organic acid transportGO:00158491010.016
spermatogenesisGO:00072832840.016
learning or memoryGO:00076111480.016
regulation of cell adhesionGO:00301551540.016
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.016
sensory perceptionGO:00076002450.016
Fly
small molecule biosynthetic processGO:00442831320.016
positive regulation of ras gtpase activityGO:0032320650.016
regulation of endocytosisGO:0030100690.016
rab protein signal transductionGO:003248210.016
engulfment of apoptotic cellGO:004365230.016
oocyte axis specificationGO:000730920.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
negative regulation of cellular component organizationGO:00511291940.015
dna metabolic processGO:00062593030.015
cytosolic calcium ion transportGO:0060401480.015
oocyte constructionGO:000730820.015
cytokine productionGO:00018163190.015
positive regulation of protein kinase activityGO:00458601440.015
chromatin organizationGO:00063252060.015
positive regulation of potassium ion transmembrane transportGO:190138130.015
negative regulation of homeostatic processGO:0032845710.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
positive regulation of organelle organizationGO:00106381280.015
regulation of intracellular transportGO:00323861590.015
axon guidanceGO:00074111410.015
regulation of organelle organizationGO:00330432890.014
skeletal system developmentGO:00015013560.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of neuron projection developmentGO:00109751690.014
regulation of secretion by cellGO:19035302490.014
regulation of vesicle mediated transportGO:00606271390.014
heart processGO:0003015940.014
porphyrin containing compound biosynthetic processGO:0006779160.014
respiratory system developmentGO:00605411900.014
actin filament organizationGO:00070151130.014
stem cell differentiationGO:00488632680.014
cell divisionGO:00513011200.014
regulation of kinase activityGO:00435492490.014
response to inorganic substanceGO:0010035960.014
carboxylic acid transportGO:00469421000.014
locomotory behaviorGO:00076261950.014
sensory system developmentGO:004888030.014
neuron migrationGO:00017641220.014
glycerolipid metabolic processGO:00464861220.014
Fly
muscle tissue developmentGO:00605373080.013
positive regulation of ion transmembrane transportGO:0034767240.013
cognitionGO:00508901490.013
stem cell proliferationGO:00720891170.013
oxidation reduction processGO:00551143420.013
negative regulation of phosphorus metabolic processGO:00105631840.013
striated muscle contractionGO:0006941450.013
reactive nitrogen species metabolic processGO:200105700.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
anatomical structure homeostasisGO:00602491450.013
regulation of translationGO:0006417710.013
single organism nuclear importGO:1902593950.013
glycoprotein metabolic processGO:00091001160.013
cellular lipid metabolic processGO:00442553230.013
Fly
organic hydroxy compound metabolic processGO:19016152030.013
Fly
cellular calcium ion homeostasisGO:00068741190.013
regulation of cellular component sizeGO:00325351210.013
cardiac chamber developmentGO:00032051080.013
protein importGO:00170381010.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
negative regulation of cell cycleGO:00457861230.013
calcium ion transport from endoplasmic reticulum to cytosolGO:1903514120.013
nucleoside monophosphate catabolic processGO:0009125590.013
response to acid chemicalGO:00011011110.013
establishment of organelle localizationGO:00516561220.013
nucleocytoplasmic transportGO:00069131390.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
positive regulation of rho gtpase activityGO:0032321410.013
gonad developmentGO:00084061410.013
hippo signalingGO:0035329110.012
positive regulation of potassium ion transmembrane transporter activityGO:190101810.012
lipid localizationGO:00108761260.012
cellular response to hormone stimulusGO:00328701500.012
negative regulation of cellular amine metabolic processGO:003323910.012
modification dependent protein catabolic processGO:00199411330.012
cellularizationGO:000734910.012
regulation of protein serine threonine kinase activityGO:00719001570.012
regulation of cytoplasmic transportGO:19036491120.012
regulation of muscle system processGO:0090257800.012
gland developmentGO:00487323300.012
development of primary sexual characteristicsGO:00451371430.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
calcium mediated signalingGO:0019722460.012
protein stabilizationGO:0050821250.012
ubiquitin dependent protein catabolic processGO:00065111290.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
response to organic cyclic compoundGO:00140701980.012
lipoprotein metabolic processGO:0042157430.012
positive regulation of transferase activityGO:00513471670.012
adult behaviorGO:00305341350.012
regulation of cytokine productionGO:00018172660.012
tetrapyrrole biosynthetic processGO:0033014160.012
organic anion transportGO:00157111370.012
t cell activationGO:00421102890.012
regulation of striated muscle contractionGO:0006942250.012
positive regulation of ion transmembrane transporter activityGO:0032414150.012
establishment of protein localization to membraneGO:0090150540.012
negative regulation of nervous system developmentGO:00519611560.012
male gamete generationGO:00482322850.012
organelle fissionGO:00482851700.012
forebrain developmentGO:00309003020.012
methylationGO:00322591340.012
synaptic vesicle localizationGO:0097479590.012
ameboidal type cell migrationGO:00016671280.012
primary neural tube formationGO:0014020950.012
proteasomal protein catabolic processGO:0010498980.012
cell activation involved in immune responseGO:00022631260.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
translationGO:0006412930.011
carbohydrate homeostasisGO:00335001280.011
negative regulation of synapse assemblyGO:005196430.011
single organismal cell cell adhesionGO:00163371310.011
atp metabolic processGO:0046034750.011
negative regulation of cell developmentGO:00107211690.011
amino acid transportGO:0006865610.011
cytosolic calcium ion homeostasisGO:0051480700.011
macromolecule methylationGO:00434141200.011
regulation of cardiac muscle contraction by calcium ion signalingGO:001088290.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
amide transportGO:00428861380.011
carbohydrate metabolic processGO:00059752300.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
exocytosisGO:00068871210.011
golgi to endosome transportGO:000689530.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
single organism cell adhesionGO:00986021560.011
dna repairGO:00062811070.011
nucleoside monophosphate metabolic processGO:0009123850.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
establishment of protein localization to plasma membraneGO:0090002340.011
positive regulation of calcium ion transportGO:0051928270.011
neurotransmitter transportGO:0006836760.011
digestive system developmentGO:00551232000.011
nuclear divisionGO:00002801580.011
regulation of cell cycle processGO:00105641600.011
blood circulationGO:00080151950.011
leukocyte migrationGO:00509001240.011
regulation of anatomical structure sizeGO:00900661780.011
cell differentiation involved in embryonic placenta developmentGO:0060706260.011
gliogenesisGO:00420631410.011
cytokinetic processGO:003250620.011
positive regulation of fat cell differentiationGO:0045600320.011
vesicle localizationGO:0051648860.011
regulation of cell activationGO:00508652890.011
embryonic organ morphogenesisGO:00485622760.011
regulation of cytoskeleton organizationGO:00514931220.010
cell fate commitmentGO:00451652100.010
tissue homeostasisGO:00018941150.010
steroid metabolic processGO:00082021190.010
lateral line system developmentGO:004892510.010
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:0010880100.010
learningGO:0007612980.010
positive regulation of cell motilityGO:20001471160.010
nuclear importGO:0051170950.010
b cell activationGO:00421131610.010
lipid biosynthetic processGO:00086101790.010
renal system developmentGO:00720012250.010
nuclear transportGO:00511691390.010
positive regulation of transmembrane transportGO:0034764290.010
peptide transportGO:00158331330.010
negative regulation of protein metabolic processGO:00512482820.010
l amino acid transportGO:0015807320.010
fertilizationGO:00095661270.010
angiogenesisGO:00015252010.010
acetylcholine transportGO:001587020.010
positive regulation of cellular component biogenesisGO:0044089940.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
cellular protein complex assemblyGO:00436231160.010
glucose homeostasisGO:00425931280.010
defecationGO:003042110.010
ribonucleoside monophosphate catabolic processGO:0009158570.010
ear developmentGO:00435832000.010
regulation of actin cytoskeleton organizationGO:0032956840.010
positive regulation of cell developmentGO:00107202370.010
atp catabolic processGO:0006200550.010

Pnpla6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
Human
nervous system diseaseDOID:86300.021
Human
immune system diseaseDOID:291400.019
disease of metabolismDOID:001466700.015
hematopoietic system diseaseDOID:7400.012
inherited metabolic disorderDOID:65500.011
central nervous system diseaseDOID:33100.011
Human